CN105535110A - Traditional Chinese medicine composition for treating senile hypertension - Google Patents
Traditional Chinese medicine composition for treating senile hypertension Download PDFInfo
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- CN105535110A CN105535110A CN201511035474.0A CN201511035474A CN105535110A CN 105535110 A CN105535110 A CN 105535110A CN 201511035474 A CN201511035474 A CN 201511035474A CN 105535110 A CN105535110 A CN 105535110A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
The invention discloses a traditional Chinese medicine composition for treating senile hypertension, and belongs to the technical field of traditional Chinese medicines. Traditional Chinese medicines including all grass of Oxalis acetosella L., all grass of Pleurospermum hookeri C. B. Clarke, stems of Chonemorpha megacalyx Pierre, roots of David currant, branches, stems and leaves of Tirpitzia ovoidea Chun et How, Celastrus gemmatus Loes, stems and leaves of Ficus erecta Thumb.var.beecheyana (Hook.et Arn.)King[F.beecheyana Hook.et Arn.] and branches and fruit of Vaccinium laetum Diels[V.mandarinorum Dielsvar.laetum(Diels)Metc which have the functions of tonifying kidneys, benefiting qi and promoting blood circulation to remove blood stasis are selected for causes of senile hypertension according to the syndrome differentiation depending treatment theory and decocted into decoction, and it is proved through clinical tests that the total effective rate reaches 93.4%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of pneumonia in aged.
Background technology
Hypertension is the one of clinical syndrome, and its main manifestations is that systemic arterial pressure raises in various degree.Modern medicine thinks that senile hypertension causes Cerebral cortex excitement and process of inhibition to be lacked of proper care by pessimal stimulations such as long-term psychentonia to cause the tiny arteriospasm of whole body, peripheral vascular resistance increases, and blood pressure raises the infringement easily causing the vitals such as the serious heart, brain, kidney.Pneumonia in aged then refers to that the age is not less than 60 years old, patients' blood is worth on the same day non-or continues to be not less than 3 persons, systolic pressure >=18.6kPa (140mmHg), diastolic pressure >=12.0kPa (90mmHg) its characteristics of incidence is that fluctuation of blood pressure is large, systolic pressure raises obviously, easily causes postural hypotension; Pneumonia in aged has higher incidence probability, clinical application is main mainly with oral drugs, comprise beta-Blocking agent, angiotensin ii receptor antagonist (ARB), calcium ion antagonist (CCB), diuretic and angiotensin converting enzyme inhibitor (ACEI) etc., said medicine antihypertensive effect is remarkable, but long-term taking can produce drug resistance and side effect, body water-electrolyte metabolism is had an impact, and cannot effectively improve complication situation.Chinese medicine is becoming the Main Means preventing and treating pneumonia in aged in recent years.A large amount of clinical practice confirms, Chinese traditional treatment hypertension not only can steadily blood pressure lowering, is conducive to the treatment of other complication simultaneously, is conducive to the raising of minimal invasive treatment's level.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of pneumonia in aged.Pneumonia in aged due to patient age comparatively large, the course of disease is longer, and delay is difficult, and prolonged illness is suffered from a deficiency of the kidney, and void then QI-blood circulation is smooth, and blood stasis stays and not all right, thus forms blood stasis due to renal deficiency card.Kidney asthenia as the principal aspect, blood stasis is mark, and cause the stasis of blood by void, therefore clinical treatment is to tonify Qi of the kidney, and blood circulation promoting and blood stasis dispelling is auxiliary.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment pneumonia in aged is made up of the Chinese medicine of following weight portion: remote mountains Herba Oxalidis Corniculatae 2-6 part, purple stem rib celery 2-6 part, Caulis Chonemorphae Megacalycis 4-7 part, Radix Ribis davidii 6-12 part, spend bavin 6-8 part, Celastrus gemmatus Loes. 2-7 part, Caulis et Folium Fici beecheyanae 15-30 part, Herba Vaccinii Bracteati 1-3 part in vain.
Preferably, remote mountains Herba Oxalidis Corniculatae 4 parts, purple stem rib celery 4 parts, Caulis Chonemorphae Megacalycis 6 parts, Radix Ribis davidii 9 parts, spend bavin 7 parts, Celastrus gemmatus Loes. 5 parts, Caulis et Folium Fici beecheyanae 23 parts, Herba Vaccinii Bracteati 2 parts in vain.
Preparation method by above-mentioned all medicinal appropriate warm water soaking 30min, 30min to 100 DEG C at a simmer.
Fang Zhong: remote mountains Herba Oxalidis Corniculatae blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing; Purple stem rib celery vital energy regualting and blood circulation-promoting, pain relieving; Caulis Chonemorphae Megacalycis is invigorated blood circulation, active; Radix Ribis davidii blood circulation promoting competent silt, thin muscle are regulated the flow of vital energy; Spend bavin blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral in vain; Celastrus gemmatus Loes. dissipating blood stasis, relax through invigorating blood circulation; Caulis et Folium Fici beecheyanae invigorating the spleen and replenishing QI; Herba Vaccinii Bracteati QI invigorating.
Clinical data
1, physical data object of study is from the hyperpietic of age more than 60 years old that 1 year January in 2012, January, my institute went to a doctor.Adopt SAS software to produce random table to divide into groups, MethodsThe cases enrolled 120 example, is divided into two groups: treatment by Chinese herbs group (observation group) 60 example, wherein female 27 example, man 33 example, and the mean age is 67 ± 3.25 years old, course of disease 5-21; Western medicine group (matched group) 60 example, wherein female 29 example, man 31 example, the mean age is 66 ± 4.12 years old, course of disease 6-22.Two groups of patients in sex, age, the course of disease, through statistical procedures, P > 0.05, not statistically significant.
2, all patients of including in of diagnostic criteria all meet the Diagnosing Hypertension standard that " Chinese hypertension guideline of prevention and treatment " works out.
Exclusion standard: age < 60 years old secondary hypertension disease, critical hypertension merges severe cardiac, brain, liver, Patients with Renal Damage.
3, Therapeutic Method matched group: according to kind and consumption or the two kind drug combinations independent with calcium antagonist, angiotensin converting enzyme inhibitor, beta-blocker, FUFANG JIANGYA PIAN etc. respectively of the depressor taken before patient assessment.Observation group: on the basis of matched group, take remote mountains Herba Oxalidis Corniculatae 4g, purple stem rib celery 4g, Caulis Chonemorphae Megacalycis 6g, Radix Ribis davidii 9g, spend bavin 7g, Celastrus gemmatus Loes. 5g, Caulis et Folium Fici beecheyanae 23g, Herba Vaccinii Bracteati 2g in vain, with appropriate warm water soaking 30min, make decoction oral for 30min to 100 DEG C at a simmer.Two groups equal 1 month is a course for the treatment of.
4, criterion of therapeutical effect clinical efficacy standard reports with reference to national cardiovascular diseases's epidemic diseases and crowd prevention and treatment the hypertension efficacy assessment standard that symposium formulates.Effective: diastolic pressure decline >=1.33kPa, and reach normal range; Though diastolic pressure is not down to normally, decline >=2.66kPa; Effective: diastolic pressure decline < 2.66kPa, but reach normal range, diastolic pressure comparatively treats front decline 1.33-2.66kPa, but does not reach normal range; Systolic pressure comparatively treats front decline >=3.99kPa; Invalid: not reach above standard.
5, observe the curative effect after the course for the treatment of of therapeutic outcome patient treatment, the routine patient of observation group 60 is effective 25 examples (41.7%) wherein, effective 31 examples (51.7%), invalid 4 examples (6.6%), total effective rate 93.4%.Matched group 60 patient is effective 20 examples (33.3%) wherein, effective 25 examples (41.7%), invalid 15 examples (25%), total effective rate 75%.Two groups are compared, and observation group's cure rate, total effective rate are obviously better than matched group, have comparability (P < 0.05).
Detailed description of the invention
Embodiment one: take remote mountains Herba Oxalidis Corniculatae 4g, purple stem rib celery 4g, Caulis Chonemorphae Megacalycis 6g, Radix Ribis davidii 9g, spend bavin 7g, Celastrus gemmatus Loes. 5g, Caulis et Folium Fici beecheyanae 23g, Herba Vaccinii Bracteati 2g in vain.With appropriate warm water soaking 30min, make decoction oral for 30min to 100 DEG C at a simmer.
Embodiment two: take remote mountains Herba Oxalidis Corniculatae 6g, purple stem rib celery 6g, Caulis Chonemorphae Megacalycis 7g, Radix Ribis davidii 12g, spend bavin 8g, Celastrus gemmatus Loes. 7g, Caulis et Folium Fici beecheyanae 30g, Herba Vaccinii Bracteati 3g in vain.With appropriate warm water soaking 30min, make decoction oral for 30min to 100 DEG C at a simmer.
Embodiment three: take remote mountains Herba Oxalidis Corniculatae 2g, purple stem rib celery 2g, Caulis Chonemorphae Megacalycis 4g, Radix Ribis davidii 6g, spend bavin 6g, Celastrus gemmatus Loes. 2g, Caulis et Folium Fici beecheyanae 15g, Herba Vaccinii Bracteati 1g in vain.With appropriate warm water soaking 30min, make decoction oral for 30min to 100 DEG C at a simmer.
Claims (2)
1. treat a Chinese medicine composition for pneumonia in aged, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: remote mountains Herba Oxalidis Corniculatae 2-6 part, purple stem rib celery 2-6 part, Caulis Chonemorphae Megacalycis 4-7 part, Radix Ribis davidii 6-12 part, spend bavin 6-8 part, Celastrus gemmatus Loes. 2-7 part, Caulis et Folium Fici beecheyanae 15-30 part, Herba Vaccinii Bracteati 1-3 part in vain.
2. a kind of Chinese medicine composition for the treatment of pneumonia in aged according to claim 1, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: preferred, remote mountains Herba Oxalidis Corniculatae 4 parts, purple stem rib celery 4 parts, Caulis Chonemorphae Megacalycis 6 parts, Radix Ribis davidii 9 parts, spend bavin 7 parts, Celastrus gemmatus Loes. 5 parts, Caulis et Folium Fici beecheyanae 23 parts, Herba Vaccinii Bracteati 2 parts in vain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511035474.0A CN105535110A (en) | 2015-12-29 | 2015-12-29 | Traditional Chinese medicine composition for treating senile hypertension |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201511035474.0A CN105535110A (en) | 2015-12-29 | 2015-12-29 | Traditional Chinese medicine composition for treating senile hypertension |
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| CN105535110A true CN105535110A (en) | 2016-05-04 |
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| CN201511035474.0A Pending CN105535110A (en) | 2015-12-29 | 2015-12-29 | Traditional Chinese medicine composition for treating senile hypertension |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352963A (en) * | 2000-11-03 | 2002-06-12 | 胡防言 | Blood pressure stabilizing pill |
| CN102397369A (en) * | 2011-11-18 | 2012-04-04 | 大连得达科技发展有限公司 | Blood pressure reducing tea for treating hypertension, and preparation method |
| CN102698092A (en) * | 2012-06-04 | 2012-10-03 | 蒋月芳 | Traditional Chinese medicine composition for treating liver-Yang hyperactivity-type hypertension |
-
2015
- 2015-12-29 CN CN201511035474.0A patent/CN105535110A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352963A (en) * | 2000-11-03 | 2002-06-12 | 胡防言 | Blood pressure stabilizing pill |
| CN102397369A (en) * | 2011-11-18 | 2012-04-04 | 大连得达科技发展有限公司 | Blood pressure reducing tea for treating hypertension, and preparation method |
| CN102698092A (en) * | 2012-06-04 | 2012-10-03 | 蒋月芳 | Traditional Chinese medicine composition for treating liver-Yang hyperactivity-type hypertension |
Non-Patent Citations (1)
| Title |
|---|
| 郭振球: ""高血压病中医研究的进展"", 《新中医》 * |
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Application publication date: 20160504 |
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