CN105534734A - Beauty composition as well as preparation method and application thereof - Google Patents
Beauty composition as well as preparation method and application thereof Download PDFInfo
- Publication number
- CN105534734A CN105534734A CN201511009946.5A CN201511009946A CN105534734A CN 105534734 A CN105534734 A CN 105534734A CN 201511009946 A CN201511009946 A CN 201511009946A CN 105534734 A CN105534734 A CN 105534734A
- Authority
- CN
- China
- Prior art keywords
- cosmetic composition
- lactoferrin
- vitamin
- content
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention belongs to the field of medical beauty and in particular relates to a beauty composition as well as a preparation method and application thereof. In parts by weight, the beauty composition provided by the invention comprises: 0.2-10 parts of lactoferrin, 5-50 parts of vitamin C and 0.05-0.5 part of a basic fibroblast growth factor. The beauty composition is simple in formula and has obvious effects in the aspects of resisting ageing and removing scars and acne marks. Experimental results show that after the beauty composition provided by the invention is continuously smeared for 28 days, arithmetic average roughness change rate of skin is less than -20%, and elasticity relative change rate is more than 25%.
Description
Technical field
The invention belongs to medical cosmetology field, particularly relate to a kind of cosmetic composition and its preparation method and application.
Background technology
Skin is the vitals being covered in human body surface, is made up of the accessory organ of epidermis, corium, subcutaneous tissue and skin, is the natural cover for defense together between external environment and body.Along with the free life of people constantly improves, people always like challenging some highly difficult free lifes, and in the process of activity, always keep away more unavoidable unnecessary reeling, therefore cause leaving some cicatrixes on skin, affect the overall image of people, also have some teenager due to hebetic reason, always unavoidably there is some comedo in skin, the thing of acne and so on, affects teen-age overall image, causes the head of a family and teenager to be very vexed for it.
In addition, the skin of people just entered natural aging state from 20 ~ 25 years old.On the one hand, along with the increase at age, sebum secretion amount reduces, and horn cell interstitial also reduces, and thus water retaining capacity reduces, and the moisture content barrier function of skin progressively fails, and starts to occur xerosis cutis problem; On the other hand, epidermis cell differentiation capability reduces, and epidermis regeneration rate slows down, keratinization deterioration, stratum corneum gets thinner, and atrophy of epidermis produces fine wrinkle.
At present, have the cosmetics and skincare product much for skin aging and cicatrix pox print on the market, but these cosmetics and skincare product formula are complicated, and at defying age with go the effect in cicatrix pox India side face not remarkable.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of cosmetic composition and its preparation method and application, cosmetic composition provided by the invention has significant defying age and goes cicatrix pox to print effect.
The invention provides a kind of cosmetic composition, with weight parts, comprising:
Lactoferrin 0.2 ~ 10 part;
Vitamin C 5 ~ 50 parts;
Basic fibroblast growth factor 0.05 ~ 0.5 part.
Preferably, described cosmetic composition also comprises solvent.
Preferably, described solvent is water.
Preferably, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 10mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 50mg/mL; The content of described cosmetic composition bFGF is 50 ~ 500 μ g/mL.
Preferably, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 1mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 15mg/mL; The content of described cosmetic composition bFGF is 50 ~ 150 μ g/mL.
The invention provides a kind of preparation method of cosmetic composition, comprise the following steps:
A), by the basic fibroblast growth factor mixing of the vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions and 0.05 ~ 0.5 weight portion, cosmetic composition is obtained.
Preferably, described step a) is:
The vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions, the basic fibroblast growth factor of 0.05 ~ 0.5 weight portion and solvent are mixed, obtains cosmetic composition.
Preferably, described solvent is water.
The invention provides the application of cosmetic composition in skin protection that the cosmetic composition described in a kind of technique scheme or the method described in technique scheme obtain.
Compared with prior art, the invention provides a kind of cosmetic composition and its preparation method and application.With weight parts, cosmetic composition provided by the invention comprises: lactoferrin 0.2 ~ 10 part; Vitamin C 5 ~ 50 parts; Basic fibroblast growth factor 0.05 ~ 0.5 part.This cosmetic composition composition formula is simple, and at defying age, goes to cicatrix pox India side face to have significant effect.Experimental result shows: smearing cosmetic composition provided by the invention continuously after 28 days, the arithmetic mean roughness rate of change <-20% of skin, elasticity relative change rate > 25%.
Detailed description of the invention
Be clearly and completely described the technical scheme in the embodiment of the present invention below, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
The invention provides a kind of cosmetic composition, with weight parts, comprising:
Lactoferrin 0.2 ~ 10 part;
Vitamin C 5 ~ 50 parts;
Basic fibroblast growth factor 0.05 ~ 0.5 part.
Cosmetic composition provided by the invention comprises lactoferrin, vitamin C and basic fibroblast growth factor.Wherein, described lactoferrin is that a kind of non-heme class ferrum in transferrins family is in conjunction with glycoprotein, in the body fluid being extensively present in organism and juice, be the immune important component part of mammal oneself, be mainly used in during food adds at present.In the present invention, the content of described lactoferrin in cosmetic composition is 0.2 ~ 10 weight portion; In an embodiment provided by the invention, the content of described lactoferrin in cosmetic composition is 0.2 ~ 1 weight portion.In the present invention, the Main Function of described lactoferrin be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The source of the present invention to described lactoferrin is not particularly limited, and adopts commercial goods.
In the present invention, described vitamin C formal name used at school L-AA, belong to human body and maintain one of healthy necessary vitamin, vitamin C is conducive to human body maintenance self immune system and normally runs, and participate in the synthesis of the collagen of body, carnitine and neurotransmitter, be necessary auxiliary compounds in the process of human metabolism.In the present invention, the content of described vitamin C in cosmetic composition is 5 ~ 50 weight portions; In an embodiment provided by the invention, the content of described lactoferrin in cosmetic composition is 5 ~ 15 weight portions.In the present invention, described ascorbic Main Function be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The present invention is not particularly limited described ascorbic source, adopts commercial goods.
In the present invention, described basic fibroblast growth factor is the one in fibroblast growth factor, is called for short bFGF.In the present invention, the content of described basic fibroblast growth factor in cosmetic composition is 0.05 ~ 0.5 weight portion; In an embodiment provided by the invention, the content of described basic fibroblast growth factor in cosmetic composition is 0.05 ~ 0.15 weight portion.In the present invention, the Main Function of described basic fibroblast growth factor be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The source of the present invention to described basic fibroblast growth factor is not particularly limited, and adopts commercial goods.
In an embodiment provided by the invention, described cosmetic composition also comprises solvent.In an embodiment provided by the invention, described solvent is water, is preferably distilled water.In an embodiment provided by the invention, the amount ratio of described solvent and lactoferrin is 0.1 ~ 10 (mL): 0.2 ~ 10 (mg); In another embodiment provided by the invention, the amount ratio of described solvent and lactoferrin is 1 (mL): 0.2 ~ 10 (mg).
In an embodiment provided by the invention, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 10mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 50mg/mL; The content of described cosmetic composition bFGF is 50 ~ 500 μ g/mL.
In another embodiment provided by the invention, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 1mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 15mg/mL; The content of described cosmetic composition bFGF is 50 ~ 150 μ g/mL.
Cosmetic composition provided by the invention contains lactoferrin, vitamin C and basic fibroblast growth factor, and this cosmetic composition composition formula is simple, and at defying age, goes to cicatrix pox India side face to have significant effect.Experimental result shows: smearing cosmetic composition provided by the invention continuously after 28 days, the arithmetic mean roughness rate of change <-20% of skin, elasticity relative change rate > 25%.
The invention provides a kind of preparation method of cosmetic composition, comprise the following steps:
A), by the basic fibroblast growth factor mixing of the vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions and 0.05 ~ 0.5 weight portion, cosmetic composition is obtained.
In method provided by the invention, directly by the vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions and the basic fibroblast growth factor mix homogeneously of 0.05 ~ 0.5 weight portion, cosmetic composition can be obtained.
Wherein, described lactoferrin is that a kind of non-heme class ferrum in transferrins family is in conjunction with glycoprotein, in the body fluid being extensively present in organism and juice, be the immune important component part of mammal oneself, be mainly used in during food adds at present.In the present invention, the Main Function of described lactoferrin be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The source of the present invention to described lactoferrin is not particularly limited, and adopts commercial goods.
In the present invention, described vitamin C formal name used at school L-AA, belong to human body and maintain one of healthy necessary vitamin, vitamin C is conducive to human body maintenance self immune system and normally runs, and participate in the synthesis of the collagen of body, carnitine and neurotransmitter, be necessary auxiliary compounds in the process of human metabolism.In the present invention, described ascorbic Main Function be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The present invention is not particularly limited described ascorbic source, adopts commercial goods.
In the present invention, described basic fibroblast growth factor is the one in fibroblast growth factor, is called for short bFGF.In the present invention, the Main Function of described basic fibroblast growth factor be by with other component synergism in cosmetic composition, thus significantly promote the senile-resistant efficacy of this cosmetic composition and go cicatrix pox to print effect.The source of the present invention to described basic fibroblast growth factor is not particularly limited, and adopts commercial goods.
In the present invention, preferably in the preparation process of cosmetic composition, add solvent, thus prepare a kind of cosmetic composition of liquid state, this process is specially:
The vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions, the basic fibroblast growth factor of 0.05 ~ 0.5 weight portion and solvent are mixed, obtains cosmetic composition.
In the preparation method of above-mentioned cosmetic composition provided by the invention, directly by the vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions and the basic fibroblast growth factor of 0.05 ~ 0.5 weight portion and solvent mix homogeneously, cosmetic composition can be obtained.Wherein, described solvent is preferably water, is more preferably distilled water.In the present invention, lactoferrin, vitamin C and basic fibroblast growth factor preferably first mix with solvent by the mode of described lactoferrin, vitamin C, basic fibroblast growth factor and solvent mixing respectively, obtain lactoferrin solution, vitamin c solution and basic fibroblast growth factor solution; Again described lactoferrin solution, vitamin c solution and basic fibroblast growth factor solution are mixed afterwards, obtain cosmetic composition provided by the invention.
Method provided by the invention can prepare to be had significant defying age and goes cicatrix pox to print the cosmetic composition of effect.Experimental result shows: smearing the obtained cosmetic composition of employing method provided by the invention continuously after 28 days, the arithmetic mean roughness rate of change <-20% of skin, elasticity relative change rate > 25%.
The invention provides the application in skin protection of cosmetic composition that described in cosmetic composition described in a kind of technique scheme or technique scheme, scheme obtains.
In application provided by the invention, use using described cosmetic composition as skin care item.In an embodiment provided by the invention, the using method of described cosmetic composition is: get this cosmetic composition of 1 ~ 5mL or 1 ~ 5g and be coated with complete face and neck, smear 1 ~ 2 every day.
For the purpose of clearer, be described in detail below by following examples.
Embodiment 1
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, lactoferrin, vitamin C, bFGF and water are mixed, obtain cosmetic composition.
Embodiment 2
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, lactoferrin, vitamin C, bFGF and water are mixed, obtain cosmetic composition.
Embodiment 3
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, lactoferrin, vitamin C, bFGF and water are mixed, obtain cosmetic composition.
Comparative example 1
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table by lactoferrin and water mixing, obtain cosmetic composition.
Comparative example 2
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table by vitamin C and water mixing, obtain cosmetic composition.
Comparative example 3
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table by bFGF and water mixing, obtain cosmetic composition.
Comparative example 4
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, lactoferrin, vitamin C and water are mixed, obtain cosmetic composition.
Comparative example 5
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, lactoferrin, bFGF and water are mixed, obtain cosmetic composition.
Comparative example 6
Prepare cosmetic composition
Recipe design:
Prepared by preparation:
According to the content in upper table, vitamin C, bFGF and water are mixed, obtain cosmetic composition.
Embodiment 4
The result of use experiment of cosmetic composition
1) roughness and flexibility test:
Recruit 90 Chinese women experimenters, in age 18-40 year, be divided into nine groups, often organize 10 people, every experimenter is all apprised of whole research process, and signs Informed Consent Form.Nine groups of experimenters smear cosmetic composition 3mL prepared by embodiment 1 ~ 3 and comparative example 1 ~ 6 (first group of cosmetic composition smearing embodiment 1 respectively every night; second group of cosmetic composition smearing embodiment 2; by that analogy; 8th group of cosmetic composition smearing comparative example 5, the 9th group of cosmetic composition smearing comparative example 6); continuous use 28 days; period does not use other skin-protection products, normal activity.Before use and use after 28 days, skin elasticity tester and MicroSkinII Multi-functional skin mirror image analysis system is used to measure the elasticity and skin texture using position by tester.Survey 5 times, average for often.Statistics uses the skin of face situation of change after cosmetic composition, and calculates arithmetic mean roughness rate of change (referred to as A) and elasticity relative change rate (referred to as B).
Wherein, mean roughness before computational methods=(after using the front mean roughness of mean roughness-use)/use of arithmetic mean roughness rate of change (A), the result of calculation of arithmetic mean roughness rate of change (A) is as shown in table 1:
Table 1 arithmetic mean roughness rate of change (A)
As shown in Table 1, after the present invention smears cosmetic composition provided by the invention, skin smoothness promotes, and illustrates that cosmetic composition provided by the invention has effect of cicatrix pox print.Simultaneously, the successful of the cosmetic composition of the embodiment of the present invention 1 is better than comparative example 1 ~ comparative example 6 (P<0.05), thus synergism is there is between each active component proved cosmetic composition provided by the invention, effect that this cosmetic composition realizes also is not only the simple superposition of effect when each component is used alone.
The computing formula of elasticity relative change rate (B) is: elasticity relative change rate=(after using the front elasticity of elasticity-use)/use front territory elasticity, and the result of calculation of elasticity relative change rate (B) is as shown in table 2:
Table 2 elasticity relative change rate (B)
As shown in Table 2, after the present invention smears cosmetic composition provided by the invention, skin elasticity rate of change is above-mentioned, illustrates that cosmetic composition provided by the invention has antidotal effect.Simultaneously, the successful of the cosmetic composition of the embodiment of the present invention 1 is better than comparative example 1 ~ comparative example 6 (P<0.05), thus synergism is there is between each active component proved cosmetic composition provided by the invention, effect that this cosmetic composition realizes also is not only the simple superposition of effect when each component is used alone.
1) experimenter's satisfaction investigation:
Experimenter's investigation table of satisfaction degree, is given a mark by experimenter, represents that experimenter's use sense is subject to from 5 to-5.Skin quality obviously improves note 5 points, and skin quality does not change note 0 point, and skin is obviously deteriorated-5.Marking result is as shown in table 3:
Table 3 experimenter satisfaction investigation result
| Group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 | Comparative example 5 | Comparative example 6 |
| Average mark | 3.8 | 3.6 | 3.9 | 1.7 | 1.6 | 2.1 | 2.4 | 3.1 | 2.9 |
Can be found out by table 3, experimenter has higher satisfaction to cosmetic composition provided by the invention.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (9)
1. a cosmetic composition, with weight parts, comprising:
Lactoferrin 0.2 ~ 10 part;
Vitamin C 5 ~ 50 parts;
Basic fibroblast growth factor 0.05 ~ 0.5 part.
2. cosmetic composition according to claim 1, is characterized in that, also comprises solvent.
3. cosmetic composition according to claim 2, is characterized in that, described solvent is water.
4. cosmetic composition according to claim 2, is characterized in that, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 10mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 50mg/mL; The content of described cosmetic composition bFGF is 50 ~ 500 μ g/mL.
5. cosmetic composition according to claim 4, is characterized in that, in described cosmetic composition, the content of lactoferrin is 0.2 ~ 1mg/mL; In described cosmetic composition, ascorbic content is 5 ~ 15mg/mL; The content of described cosmetic composition bFGF is 50 ~ 150 μ g/mL.
6. a preparation method for cosmetic composition, comprises the following steps:
A), by the basic fibroblast growth factor mixing of the vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions and 0.05 ~ 0.5 weight portion, cosmetic composition is obtained.
7. preparation method according to claim 6, is characterized in that, described step a) is:
The vitamin C of the lactoferrin of 0.2 ~ 10 weight portion, 5 ~ 50 weight portions, the basic fibroblast growth factor of 0.05 ~ 0.5 weight portion and solvent are mixed, obtains cosmetic composition.
8. preparation method according to claim 7, is characterized in that, described solvent is water.
9. the application of cosmetic composition in skin protection that the cosmetic composition described in an any one of Claims 1 to 5 or the method described in any one of claim 6 ~ 8 obtain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511009946.5A CN105534734B (en) | 2015-12-25 | 2015-12-25 | A kind of cosmetic composition and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511009946.5A CN105534734B (en) | 2015-12-25 | 2015-12-25 | A kind of cosmetic composition and its preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105534734A true CN105534734A (en) | 2016-05-04 |
| CN105534734B CN105534734B (en) | 2018-06-15 |
Family
ID=55814670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201511009946.5A Active CN105534734B (en) | 2015-12-25 | 2015-12-25 | A kind of cosmetic composition and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105534734B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07196529A (en) * | 1993-12-29 | 1995-08-01 | Morinaga Milk Ind Co Ltd | Wound-curing agent, cosmetic and hair tonic |
| CN104940065A (en) * | 2015-06-19 | 2015-09-30 | 青岛克立克信息技术有限公司 | Skin whitening emulsion |
-
2015
- 2015-12-25 CN CN201511009946.5A patent/CN105534734B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07196529A (en) * | 1993-12-29 | 1995-08-01 | Morinaga Milk Ind Co Ltd | Wound-curing agent, cosmetic and hair tonic |
| CN104940065A (en) * | 2015-06-19 | 2015-09-30 | 青岛克立克信息技术有限公司 | Skin whitening emulsion |
Non-Patent Citations (2)
| Title |
|---|
| 李俊: "《美容药物学》", 31 August 2006, 科学出版社 * |
| 陈惠: "《基础生物化学》", 28 February 2014, 中国农业出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105534734B (en) | 2018-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2842582T3 (en) | Anigozanthos Flavidus extract for cosmetic use | |
| US10124030B2 (en) | Skincare preparations | |
| RU2501544C2 (en) | Composition and method of treating pathological skin conditions | |
| JP6554540B2 (en) | Composition for treating skin conditions | |
| US20230000749A1 (en) | Stem cell stimulating compositions and methods | |
| ES2856480T3 (en) | Cosmetic uses of swertiamarin | |
| CN106691923A (en) | Composition and preparation for esthetic restoration, as well as preparation method and application thereof | |
| JP2023504951A (en) | Hypoxia-induced targeted anti-aging repair method | |
| KR101895037B1 (en) | Hydrogel comprising spicule and use thereof | |
| JP2009108006A (en) | Method for producing gel sheet, gel sheet and sheet-like cosmetic | |
| JP2009242311A (en) | Scf secretion inhibitor and skin care preparation for external use for making skin pore inconspicuous | |
| CN107260574A (en) | The topical compositions of glycosaminoglycan comprising crosslinking | |
| US20160220479A1 (en) | Topical compounds containing adipose-derived hormones for the rejuvenation of skin | |
| US20220175625A1 (en) | New cosmetic use of porous spheres of metal oxide | |
| CN105534734A (en) | Beauty composition as well as preparation method and application thereof | |
| CN105496810A (en) | Beautifying composition and preparing method and application thereof | |
| US20140234433A1 (en) | Topical Composition for Stimulating Epidermis and Dermis Layers of the Skin | |
| US20230000759A1 (en) | Ppar agonist complex and methods of use | |
| CN105686967B (en) | A kind of cosmetic composition and its preparation method and application | |
| EP1790325A1 (en) | Cosmetic hydrodispersions | |
| JP2009108005A (en) | Gel sheet and sheet-like cosmetic | |
| GB2540319B (en) | Topical composition including a combination of extracts | |
| US11026876B2 (en) | Composition for improving skin condition comprising chemokines | |
| WO2017019793A1 (en) | Microdelivery triple acid | |
| US20230190587A1 (en) | Cosmetic composition comprising sucrose ester and lauroyl lysine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant |