CN105520758A - Closure apparatus for patent foramen ovale or small atrial septal defect - Google Patents

Closure apparatus for patent foramen ovale or small atrial septal defect Download PDF

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Publication number
CN105520758A
CN105520758A CN201610035276.2A CN201610035276A CN105520758A CN 105520758 A CN105520758 A CN 105520758A CN 201610035276 A CN201610035276 A CN 201610035276A CN 105520758 A CN105520758 A CN 105520758A
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CN
China
Prior art keywords
septal defect
atrial septal
foramen ovale
patent foramen
closer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610035276.2A
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Chinese (zh)
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CN105520758B (en
Inventor
高伟
于存涛
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Fuwai Hospital of CAMS and PUMC
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Individual
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Priority to CN201610035276.2A priority Critical patent/CN105520758B/en
Publication of CN105520758A publication Critical patent/CN105520758A/en
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Publication of CN105520758B publication Critical patent/CN105520758B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00601Implements entirely comprised between the two sides of the opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623Introducing or retrieving devices therefor

Abstract

The invention belongs to the field of medical equipment implanted to human bodies, and specifically to closure apparatus for patent foramen ovale or small atrial septal defect, and a novel conveying apparatus for the closure apparatus for patent foramen ovale or small atrial septal defect; the closure apparatus for patent foramen ovale or small atrial septal defect comprises a closure unit, wherein the closure unit comprises two closure devices that are arranged in opposite; an embedded part is arranged at the end part of each closure device; the embedded part is crimped and can be embedded in the circumferential side of patent foramen ovale or atrial septal defect; the conveying apparatus comprises a pushing sheathing canal and a closure device accommodating apparatus; the closure device accommodating apparatus is arranged in the pushing sheathing canal; and the first closure device and the second closure device are arranged in the closure device accommodating apparatus. The closure apparatus has the beneficial effects that the closure apparatus is small in implantation apparatus, easy to position, and capable of being released repeatedly and recycled so as to further block atrium level shunt on the basis of accurately placing the closure devices.

Description

The closing device of a kind of patent foramen ovale or Small Atrial Septal Defect
Technical field
The invention belongs to the medical instruments field of implant into body, be specifically related to a kind of novel patent foramen ovale or Small Atrial Septal Defect closing device.
Background technology
Oval foramen (Patentforamenoval, PFO) is the normal channel of the blood of fetal period, is an one-way cock structure, its role is to fetal period and makes room blood flow to left atrium by oval foramen from right atrium, to ensure normal fetal circulation.After breathing appears in fetal birth, along with pulmonary vascular resistance reduces, oval foramen one-way cock is closed, and room horizontal traffic disappears.But in normal adult crowd, about there is the Adult Groups oval foramen of 1/3 not close, still retain a little room horizontal flow (be less than 5mm, be greater than 5mm and be namely called atrial septal defect).Generally, this type of crowd due to oval foramen shunt volume few, both asymptomatic, also without long term complication.But evidence show at present, in this part crowd, there is the risk of cerebral infarction higher than normal population in generation infective endocarditis and person in middle and old age's phase.
Atrial septal defect (Atrialseptaldefect, ASD) is a kind of common congenital heart disease, is that interatrial septum occurs abnormal in embryo development procedure, causes between left and right atrium and leave over hole.Atrial septal defect can occur separately, also can deposit with the cardiovascular malformation of other types.Most atrial septal defect diameter is greater than 5mm, the larger atrial septal defect being at present greater than 5mm for diameter is applicable to by surgical operation or Wicresoft's transcatheter operative treatment, but surgery operating wound is large, operation risk is high, post-operative recovery time is long, and transcatheter operation then needs to place in vivo a larger metal atrial septal defect plugging device.Because internal cardiac structures is complicated, get involved postoperative short-term and all may increase the occurrence risk of complication long term, and larger stopper is placed in heart, a lot of patient not easily accepts, and transcatheter is difficult to accomplish repeatedly to discharge recovery in addition.
Summary of the invention
For the deficiency existed in background technology, the object of the present invention is to provide a kind of novel patent foramen ovale or Small Atrial Septal Defect closing device, be used for the treatment of patent foramen ovale or the atrial septal defect of 1-5mm.
Technical scheme of the present invention is as follows: a kind of novel patent foramen ovale or Small Atrial Septal Defect closing device, described patent foramen ovale or Small Atrial Septal Defect closing device comprise a closed cell, described closed cell end is Embedded Division, described Embedded Division is curling shape, can embed patent foramen ovale or week side, Small Atrial Septal Defect place.
Further, described closed cell comprises two closers, and described two closers are oppositely arranged;
Described closer comprises an extension and an Embedded Division, described two closers are connected by extension, and the junction of two extensions connects a delivery guidewire jointly, described Embedded Division embeds patent foramen ovale or week side, Small Atrial Septal Defect place, and the position embedded by described two Embedded Divisions is relative.
Further, described extension is elastic metallic material; Described Embedded Division is memory metal material.
Further, described elastic metallic material is beryllium-bronze or spring steel; Described memory metal material is Ni-Ti alloy.
The conveyer device of a kind of novel patent foramen ovale or Small Atrial Septal Defect closing device, for carrying above-mentioned novel patent foramen ovale or Small Atrial Septal Defect closing device, described conveyer device comprises pushing sheath tube and a closer storing apparatus, described closer storing apparatus is placed in described pushing sheath tube, and described closed cell is contained in described closer storing apparatus.
Further, described pushing sheath tube front end is through hole, and a closer release portion is extended in described through hole front end, and described closer release portion is cylindric, and in described closer release portion cylindrical shape, diameter of section is identical with described through-hole diameter size;
Described pushing sheath tube front end outer side is provided with spacing block set;
Described closer release portion outside is provided with the guide portion of surface smoothing.
Further, described through hole is provided with closer storing apparatus slideway, for closer storing apparatus is guided to through hole in contrast to the side of closer release portion.
Further, have a spatial accommodation in described closer storing apparatus, described spatial accommodation is cylindric, and the interior diameter of described spatial accommodation is less than the diameter of through hole, and the overall diameter of storing apparatus is greater than the diameter of through hole.
Further, the first closer and the second closer are placed in both sides relative in closer spatial accommodation.
The method of closing at patent foramen ovale or Small Atrial Septal Defect place, apply above-mentioned novel patent foramen ovale or the conveyer device of Small Atrial Septal Defect closing device, described method is:
A) application guides seal wire, through upper limb/veins of lower extremity, to right atrium, arrives oval foramen or atrial septal defect place, and protrudes out through oval foramen or atrial septal defect place;
B) along guiding seal wire, the pushing sheath tube of closing device is delivered to oval foramen or atrial septal defect place, after portion to be guided enters defect, extracts out and guide seal wire, push delivery guidewire, make extension and Embedded Division enter side, left room;
C) push delivery guidewire further again, described extension is launched, described Embedded Division is conflicted in patent foramen ovale or week side, atrial septal defect place;
D) in 6-10 minute, radiography observes the conflict position of Embedded Division, adjust conflict position and tractive delivery guidewire, Embedded Division is made to be embedded in defect week side, after 10-15 minute, memory metal completes curling, the curling embedding patent foramen ovale of described Embedded Division or week side, atrial septal defect place, complete closed, release closing device.
Beneficial effect of the present invention: by technical scheme of the present invention, can realize carrying out Wicresoft to the patent foramen ovale or atrial septal defect that are less than 5mm and close, embedded device is little, easy location, repeatedly can discharge recovery, and then realize guaranteeing to arrange closer on position accurately, and resistance flowing effect is strong.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention;
Fig. 2 is the closing device installation procedure figure that the embodiment of the present invention proposes.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is explained in further detail.Should be appreciated that specific embodiment described herein only for explaining the present invention, being not intended to limit the present invention.
On the contrary, the present invention is contained any by the substituting of making on marrow of the present invention and scope of defining of claim, amendment, equivalent method and scheme.Further, in order to make the public have a better understanding to the present invention, in hereafter details of the present invention being described, detailedly describe some specific detail sections.
As shown in Figure 1, for the structural representation of one embodiment of the invention, this structural representation illustrates the overall structure of described a kind of novel patent foramen ovale or atrial septal defect closing device, and described patent foramen ovale or Small Atrial Septal Defect closing device are arranged on defect place.
Described novel patent foramen ovale or atrial septal defect are closed comprises the first closer 1 and the second closer 2, and atrial septal defect place hooks and closes by described first closer 1 and described second closer 2 jointly, described first closer 1 and the second closer 2 structure identical.
Described first closer 1 comprises the first extension 11 and the first Embedded Division 12, described first extension 11 is connected with described first Embedded Division 12, described second closer 2 comprises the second extension 21 and the second Embedded Division 22, described second extension 21 is connected with described second Embedded Division 22, and described first extension 11 is connected by central connection point 3 with the second extension 21, and this central connection point 3 described connects delivery guidewire 6, by delivery guidewire 6, can realize controlling while first, second closer 1,2.
Described first extension 11 and the second extension 21 are connected in delivery guidewire 6 by screw joining manner.
Described first Embedded Division 12 and the second Embedded Division 22 are the curling shape extended inside central connection point 3, under the state that the first closer 1 and the second closer 2 are thoroughly opened, described first Embedded Division 12 and the second Embedded Division 22 embed described patent foramen ovale or week side, atrial septal defect place, being specially the first Embedded Division 12 with the place embedded by the second Embedded Division 22 is position relative on all sides in patent foramen ovale or atrial septal defect place, and is closed by complete for atrial septal defect place hook in conjunction with the first extension 11 and the second extension 21.
Wherein said first extension 11 and the second extension 21 are elastic metallic material, specifically can be in prior art, have elastic metal material, such as beryllium-bronze, spring steel etc.; Described first Embedded Division 12 and the second Embedded Division 22 are memory metal material, specifically can be the Ni-Ti alloys such as ambrose alloy, titanium ferronickel, titanium nickel chromium triangle of admiring.
The present invention also provides one for the conveyer device of novel patent foramen ovale or atrial septal defect closing device, described conveyer device comprises pushing sheath tube 4 and a closer storing apparatus 5, described closer storing apparatus 5 is placed in described pushing sheath tube 4, described pushing sheath tube 4 front end is through hole 41, a closer release portion 42 is extended in all sides, described through hole 41 front end, described closer release portion 42 is cylindric, and described cylindrical inner is smooth, in cylindric, diameter of section is identical with described through hole 41 diameter, described closer release portion 42 weeks sides are provided with the guide portion 45 of surface smoothing, described guide portion 45 entirety is smooth surface, after arrival patent foramen ovale or atrial septal defect place, closer release portion 42 is made to be placed in patent foramen ovale or centre, atrial septal defect place by the guiding of smooth surface, described through hole 41 is provided with closer storing apparatus slideway 43 in contrast to the side of closer release portion 42, for closer storing apparatus 5 is guided to through hole 41 place, also may arrange restraint device 44 outside described pushing sheath tube 4, described restraint device 44 is projection, for being stuck in outside atrial septal defect place, avoids closer release portion 42 to protrude out too much.
In described closer storing apparatus 5, there is a spatial accommodation, described first closer 1 and the second closer 2 are all placed in this spatial accommodation, and described spatial accommodation is cylindric, the interior diameter of described spatial accommodation is slightly less than the diameter of through hole 41, and the overall diameter of storing apparatus 5 is slightly larger than the diameter of through hole 51.
When the first closer 1 and the second closer 2 are for drawing close state, the first closer 1 and the second closer 2 are placed in relative both sides.
As shown in Figure 2, the present invention also provides a kind of application above-mentioned conveyer device, and to the operational approach of the placement of patent foramen ovale or atrial septal defect closing device, the operational approach of described placement specifically comprises the steps:
A) application guides seal wire, through upper limb/veins of lower extremity, to right atrium, arrives oval foramen or atrial septal defect place, and protrudes out through oval foramen or atrial septal defect place;
B) along guiding seal wire, the pushing sheath tube of closing device is delivered to oval foramen or atrial septal defect place, after portion to be guided enters defect, extracts out and guide seal wire, push delivery guidewire, make extension and Embedded Division enter side, left room;
C) push delivery guidewire further again, described extension is launched, described Embedded Division is conflicted in patent foramen ovale or week side, atrial septal defect place;
D) in 6-10 minute, radiography observes the conflict position of Embedded Division, adjust conflict position and tractive delivery guidewire, Embedded Division is made to be embedded in defect week side, after 10-15 minute, memory metal completes curling, the curling embedding patent foramen ovale of described Embedded Division or week side, atrial septal defect place, complete closed, release closing device; Realize hooking completely closing patent foramen ovale or atrial septal defect, complete placement, if when placing inaccurate, by tractive seal wire in effective time before memory metal distortion, draw, under the position limitation effect of storing apparatus front end, first closer and the second closer are recovered in closer storing apparatus, again adjust position, release closer, until accurately install.

Claims (10)

1. a novel patent foramen ovale or Small Atrial Septal Defect closing device, it is characterized in that, described patent foramen ovale or Small Atrial Septal Defect closing device comprise a closed cell, described closed cell end is Embedded Division, described Embedded Division is curling shape, can embed patent foramen ovale or week side, Small Atrial Septal Defect place.
2. the novel patent foramen ovale of one according to claim 1 or Small Atrial Septal Defect closing device, is characterized in that, described closed cell comprises two closers, and described two closers are oppositely arranged;
Described closer comprises an extension and an Embedded Division, described two closers are connected by extension, and the junction of two extensions connects a delivery guidewire jointly, described Embedded Division embeds patent foramen ovale or week side, Small Atrial Septal Defect place, and the position embedded by described two Embedded Divisions is relative.
3. the novel patent foramen ovale of one according to claim 2 or Small Atrial Septal Defect closing device, is characterized in that, described extension is elastic metallic material; Described Embedded Division is memory metal material.
4. the novel patent foramen ovale of one according to claim 3 or Small Atrial Septal Defect closing device, is characterized in that, described elastic metallic material is beryllium-bronze or spring steel; Described memory metal material is Ni-Ti alloy.
5. the conveyer device of a novel patent foramen ovale or Small Atrial Septal Defect closing device, for the novel patent foramen ovale of carrying one of the claims 1-4 described or Small Atrial Septal Defect closing device, it is characterized in that, described conveyer device comprises pushing sheath tube and a closer storing apparatus, described closer storing apparatus is placed in described pushing sheath tube, and described closed cell is contained in described closer storing apparatus.
6. the conveyer device of a kind of novel patent foramen ovale according to claim 5 or Small Atrial Septal Defect closing device, it is characterized in that, described pushing sheath tube front end is through hole, a closer release portion is extended in described through hole front end, described closer release portion is cylindric, and in described closer release portion cylindrical shape, diameter of section is identical with described through-hole diameter size;
Described pushing sheath tube front end outer side is provided with spacing block set;
Described closer release portion outside is provided with the guide portion of surface smoothing.
7. the conveyer device of a kind of novel patent foramen ovale according to claim 6 or Small Atrial Septal Defect closing device, it is characterized in that, described through hole is provided with closer storing apparatus slideway, for closer storing apparatus is guided to through hole in contrast to the side of closer release portion.
8. the conveyer device of a kind of novel patent foramen ovale according to claim 6 or Small Atrial Septal Defect closing device, it is characterized in that, in described closer storing apparatus, there is a spatial accommodation, described spatial accommodation is cylindric, the interior diameter of described spatial accommodation is less than the diameter of through hole, and the overall diameter of storing apparatus is greater than the diameter of through hole.
9. the conveyer device of a kind of novel patent foramen ovale according to claim 8 or Small Atrial Septal Defect closing device, is characterized in that, the first closer and the second closer are placed in both sides relative in closer spatial accommodation.
10. the method for closing at patent foramen ovale or Small Atrial Septal Defect place, the conveyer device of the described novel patent foramen ovale of one of application the claims 5-9 or Small Atrial Septal Defect closing device, it is characterized in that, described method is:
A) application guides seal wire, through upper limb/veins of lower extremity, to right atrium, arrives oval foramen or atrial septal defect place, and protrudes out through oval foramen or atrial septal defect place;
B) along guiding seal wire, the pushing sheath tube of closing device is delivered to oval foramen or atrial septal defect place, after portion to be guided enters defect, extracts out and guide seal wire, push delivery guidewire, make extension and Embedded Division enter side, left room;
C) push delivery guidewire further again, described extension is launched, described Embedded Division is conflicted in patent foramen ovale or week side, atrial septal defect place;
D) in 6-10 minute, radiography observes the conflict position of Embedded Division, adjust conflict position and tractive delivery guidewire, Embedded Division is made to be embedded in defect week side, after 10-15 minute, memory metal completes curling, the curling embedding patent foramen ovale of described Embedded Division or week side, atrial septal defect place, complete closed, release closing device.
CN201610035276.2A 2016-01-19 2016-01-19 A kind of closing device of acleistocardia or Small Atrial Septal Defect Active CN105520758B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610035276.2A CN105520758B (en) 2016-01-19 2016-01-19 A kind of closing device of acleistocardia or Small Atrial Septal Defect

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Application Number Priority Date Filing Date Title
CN201610035276.2A CN105520758B (en) 2016-01-19 2016-01-19 A kind of closing device of acleistocardia or Small Atrial Septal Defect

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183787A1 (en) * 2001-06-01 2002-12-05 Velocimed, L.L.C. Closure devices, related delivery methods and tools, and related methods of use
WO2006110147A2 (en) * 2005-04-08 2006-10-19 Proximare, Inc. Patent foramen ovale closure devices, delivery apparatus and related methods and systems
US20070198057A1 (en) * 2006-02-21 2007-08-23 Daniel Gelbart Method and device for closing holes in tissue
US20080039804A1 (en) * 2006-08-09 2008-02-14 Coherex Medical, Inc. Systems and devices for reducing the size of an internal tissue opening
CN101234042A (en) * 2008-01-31 2008-08-06 上海交通大学 Method for knitting degradable heart atrial septal defect plugging device
US20100198254A1 (en) * 2009-01-30 2010-08-05 Cook Incorporated Vascular closure device
CN103118602A (en) * 2010-06-11 2013-05-22 随行医疗技术公司 System and method for transapical access and closure
CN105163671A (en) * 2013-03-14 2015-12-16 心肺医疗股份有限公司 Tissue and vascular closure devices and methods of use thereof
CN205458820U (en) * 2016-01-19 2016-08-17 高伟 Acleistocardia or little atrial septal defect's closing device and conveyor thereof

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183787A1 (en) * 2001-06-01 2002-12-05 Velocimed, L.L.C. Closure devices, related delivery methods and tools, and related methods of use
WO2006110147A2 (en) * 2005-04-08 2006-10-19 Proximare, Inc. Patent foramen ovale closure devices, delivery apparatus and related methods and systems
US20070198057A1 (en) * 2006-02-21 2007-08-23 Daniel Gelbart Method and device for closing holes in tissue
US20080039804A1 (en) * 2006-08-09 2008-02-14 Coherex Medical, Inc. Systems and devices for reducing the size of an internal tissue opening
CN101234042A (en) * 2008-01-31 2008-08-06 上海交通大学 Method for knitting degradable heart atrial septal defect plugging device
US20100198254A1 (en) * 2009-01-30 2010-08-05 Cook Incorporated Vascular closure device
CN103118602A (en) * 2010-06-11 2013-05-22 随行医疗技术公司 System and method for transapical access and closure
CN105163671A (en) * 2013-03-14 2015-12-16 心肺医疗股份有限公司 Tissue and vascular closure devices and methods of use thereof
CN205458820U (en) * 2016-01-19 2016-08-17 高伟 Acleistocardia or little atrial septal defect's closing device and conveyor thereof

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