CN1055092C - Preparation of gluconic acid by hydrogen peroxide oxidizing process - Google Patents
Preparation of gluconic acid by hydrogen peroxide oxidizing process Download PDFInfo
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- CN1055092C CN1055092C CN98111125A CN98111125A CN1055092C CN 1055092 C CN1055092 C CN 1055092C CN 98111125 A CN98111125 A CN 98111125A CN 98111125 A CN98111125 A CN 98111125A CN 1055092 C CN1055092 C CN 1055092C
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- hydrogen peroxide
- gluconic acid
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- preparation
- glucose
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Abstract
The present invention discloses a hydrogen peroxide solution oxidizing method for preparing gluconic acid. In the technology of the present invention, dextrose is dissolved in water, is added with granular activated carbon and is stirred and heated; a hydrogen peroxide solution is added, and temperature is controlled; heat preservation reaction is continued after that materials are put in; clear liquid is filtered out; the conversion rate of dextrose is more than 95%. The present invention has the advantages of high product purity, simple technology, low production cost, simple and easy operation, no three waste and good working environment and is suitable for industrialized production; gluconic acid produced by the present invention can be widely used for industries of medicine, food, electroplation, water processing, corrosion prevention, etc.
Description
The present invention relates to a kind of production method of gluconic acid.
Gluconic acid is a kind of biochemical reagents.By gluconic acid synthetic molysite, zinc salt, calcium salt, manganese salt, mantoquita etc. is the approach that human body is mended trace element.Making complexing agent and water quality stabilizer aspect water treatment, the plating, have scale removal, corrosion inhibition.It has acidity, and sterilization, preservative activity are arranged again, is again can metabolic material, makes acidic flavoring agent, sanitas on food.
" Fine Organic Chemical product technical manual " (Science Press, first version in 1991, the first impression) a kind of production method of gluconic acid is disclosed in volume two P1070 " Gluconolactone ", this method is decomposed calglucon or the ion exchange resin decalcification by mineral acid, makes gluconic acid solution, at 70 ℃ with its concentrating under reduced pressure, making concentration is 80～85%, cooling is below 40 ℃, and crystallization makes solid phase prod gluconic acid or lactones.This method complex process, the cost height.
The objective of the invention is to provide a kind of production method of gluconic acid---preparation of gluconic acid by hydrogen peroxide oxidizing process, this method technology is simple, and production cost is low.
The object of the present invention is achieved like this: add glucose, be dissolved in water, add granulated active carbon, stir, heating adds hydrogen peroxide, and controlled temperature after feeding intake, continues insulation reaction, leaches clear liquid.
Temperature is 70～85 ℃, and in 2～4 hours reaction times, the mol ratio of glucose and hydrogen peroxide is 1: 1, and grain active carbon is 5～10% of a glucose.
The present invention makes catalyzer with granulated active carbon, uses hydrogen peroxide oxidation glucose.Inversion rate of glucose is more than 95%, the product purity height.Technology is simple, and production cost is low.Operate simple and easy, the no three wastes, production environment is good, is suitable for suitability for industrialized production.The gluconic acid of producing with the present invention can be widely used in medicine, food, plating, water treatment, industry such as anticorrosion.
Elaborate below in conjunction with embodiment.
Embodiment 1:
In the 500ml beaker, add 114 gram glucose, add the 200ml water dissolution; add 10 gram granulated active carbons, stir heating; in the time of 70 ℃, drip hydrogen peroxide 80 grams, 80 ℃ of controlled temperature; feed intake finish after; continued insulation reaction 3 hours, it is light yellow leaching clear liquid, and weighing is 129 grams; chemical examination gluconic acid content is 52.94%, and transformation efficiency reaches 95%.
Embodiment 2:
In the 800ml beaker, add 250 gram glucose, add the 500ml water dissolution; add last time exhausted granulated active carbon 10 grams and newly add 10 grams, totally 20 grams stir; heating in the time of 70 ℃, drips hydrogen peroxide 175 grams; 80 ℃ of controlled temperature, feed intake finish after, continued insulation reaction 3 hours; leach clear liquid 550 grams; for light yellow, chemical examination gluconic acid content is 47.54%, and transformation efficiency reaches 96%.
Claims (1)
1. preparation of gluconic acid by hydrogen peroxide oxidizing process is characterized in that adding glucose, is dissolved in water; add granulated active carbon, stir, heating; add hydrogen peroxide, controlled temperature is after feeding intake; continue insulation reaction; leach clear liquid, temperature is 70～85 ℃, 2～4 hours reaction times; the mol ratio of glucose and hydrogen peroxide is 1: 1, and grain active carbon is 5～10% of a glucose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98111125A CN1055092C (en) | 1998-01-20 | 1998-01-20 | Preparation of gluconic acid by hydrogen peroxide oxidizing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98111125A CN1055092C (en) | 1998-01-20 | 1998-01-20 | Preparation of gluconic acid by hydrogen peroxide oxidizing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1188114A CN1188114A (en) | 1998-07-22 |
| CN1055092C true CN1055092C (en) | 2000-08-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98111125A Expired - Fee Related CN1055092C (en) | 1998-01-20 | 1998-01-20 | Preparation of gluconic acid by hydrogen peroxide oxidizing process |
Country Status (1)
| Country | Link |
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| CN (1) | CN1055092C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103739478B (en) * | 2013-12-09 | 2016-01-20 | 西北大学 | A kind of method of producing Sunmorl N 60S |
| CN107337597A (en) * | 2016-05-03 | 2017-11-10 | 济南圣泉集团股份有限公司 | A kind of synthetic method of xylonic |
| CN108218683B (en) * | 2016-12-09 | 2021-04-09 | 中科院大连化物所盘锦产业技术研究院有限公司 | Method for preparing gluconic acid and salt by oxidizing glucose under catalysis of gold |
| US11203769B1 (en) | 2017-02-13 | 2021-12-21 | Solugen, Inc. | Hydrogen peroxide and gluconic acid production |
| CN110724211B (en) * | 2019-10-31 | 2021-09-17 | 汕尾市海洋产业研究院 | High-value comprehensive utilization method of shrimp and crab shells based on reducing sugar catalytic oxidation and application thereof |
| CN115154415B (en) * | 2022-08-04 | 2024-03-08 | 山东新华制药股份有限公司 | Preparation method of calcium gluconate injection |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1019819B (en) * | 1990-11-27 | 1992-12-30 | 凌源钢铁公司 | Production of pellet with reveert as core |
-
1998
- 1998-01-20 CN CN98111125A patent/CN1055092C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1019819B (en) * | 1990-11-27 | 1992-12-30 | 凌源钢铁公司 | Production of pellet with reveert as core |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1188114A (en) | 1998-07-22 |
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