CN105496939A - Daily antiallergic protective liquid for baby wet tissue and preparation method of daily antiallergic protective liquid - Google Patents
Daily antiallergic protective liquid for baby wet tissue and preparation method of daily antiallergic protective liquid Download PDFInfo
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The invention provides daily antiallergic protective liquid for a baby wet tissue and a preparation method of the daily antiallergic protective liquid. The preparation method specifically comprises the following steps of (1) dissolving 1 part of konjac flour into 50 to 80 parts of weakly acidic solution in terms of parts by volume, standing for 2 to 3 h, performing filtering separation treatment after sufficient swelling, taking supernatant liquor to concentrate, and obtaining an aqueous solution containing the konjac flour through high-temperature sterilization; (2) removing surface impurities from radix ophiopogonis, crushing the treated radix ophiopogonis into powdery radix ophiopogonis, putting 1 part by weight of powdery radix ophiopogonis into 80 to 100 parts of water, boiling, performing reflux extraction treatment, and obtaining an aqueous solution containing ophiopogonpolysaccharide after concentrating; (3) mixing the aqueous solution containing the konjac flour with the aqueous solution containing the ophiopogonpolysaccharide, heating and stirring, filtering to remove impurities, sterilizing and cooling to room temperature, sequentially adding probiotics, vitamin C, fish oil, amino acid and deionized water, adjusting the PH value of the solution to be 6 to 6.5 by utilization of lemongrass, continuously stirring till the solution is uniform, and obtaining the daily antiallergic protective liquid for the baby wet tissue.
Description
Technical field:
The invention belongs to hygienic article technical field, daily antiallergic protective liquid being specifically related to a kind of baby wipes and preparation method thereof.
Background technology:
Anaphylaxis is the tissue injury caused by the immunne response of endogenous or the made cell of exogenous antigen or humoral, namely the reaction of the tissue injury that immunifacient body occurs when again accepting same antigen and stimulating or dysfunction is referred to, feature be outbreak rapidly, strong reaction, disappear very fast, generally can not disorganize cell, also can not cause tissue injury.Anaphylaxis source comprises some food, animal skin, pollen, chemical substance etc., if these materials and skin come in contact, then there will be the symptom such as redness, urticaria.
Nearest recent decades, there is the trend increased in the incidence rate of child's anaphylactic disease, and serious dermatitis more easily occurs less baby, but anaphylactic disease can be prevented in getting up early, and prevention is exactly best treatment.Prevent the preventive measure of infantile allergy, can set about from aspects such as the diet of baby, environment, clothing, custom and toys, reach natural, environmental protection, safety, the requirement such as health.
Baby wipes is baby's routine use the articles for daily use comparatively frequently, and the formula of baby wipes all requires nontoxic non-stimulated usually, can not cause the skin allergy that baby is tender and lovely.The disclosed babywipe of Chinese patent CN104473800A (publication date 2015.4.1), comprise solution and carrier, containing green tea extract, camomile extract, Flos Lonicerae extract, olive oil, eucalyptus oil and deionized water in solution, obtain that there is cleaning function, more soft and moist to infant skin, antiinflammatory, antiinflammatory, antipruritic function, redness and allergy can not be caused, non-stimulated to infant skin.Have above-mentioned technology known, current baby wipes can reach and baby can not be caused red and swollen and irritated, but little to the effect of the prevention and therapy of allergy, and when skin allergy appears in baby, the baby wipes with antianaphylaxis will be very convenient.
Cause the reason of irritated effect complicated in human body, relate to number of ways and gene, the active function factor much natural at present all comes from animals and plants, and they have good anti-allergic effects, and its anti-allergic effects does the synergistic result of kind of composition.Simultaneously, the exploitation of the antianaphylaxis function of probiotic bacteria also becomes new study hotspot gradually, the disclosed non-viable material for the probiotic derived of prevention and therapy allergy of Chinese patent CN102575224A (publication date 2012.7.11), from culture fluid supernatant, unvital probiotic composition is obtained by exponential phase after LGG continuous culture methods, match for diet food with the compositions of other effective doses, reach effect of prevention and therapy allergy.
Antiallergic activity composition konjacmannan, flavone compound and probiotic bacteria are joined the formula of baby wipes by the present invention, and obtain by the auxiliary of other auxiliary agents such as vitamin C, fish oil the baby wipes that can be used for the protection of daily antiallergic.
Summary of the invention:
The technical problem to be solved in the present invention daily antiallergic protective liquid being to provide a kind of baby wipes and preparation method thereof, adopt novel konjacmannan, Radix Ophiopogonis polysaccharide and probiotic bacteria natural antibacterial active component as functional agent, and wetting agent, emollient and vitamin etc. that ilities is excellent, obtain antiallergic protection gentle, the protective liquid that baby can use for a long time, safe and effective, secure.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of baby wipes of daily antiallergic protection, it is characterized in that, the baby wipes of described daily antiallergic protection comprises non-woven fabrics and antiallergic solution, described antiallergic solution comprises konjacmannan, Radix Ophiopogonis polysaccharide, probiotic bacteria, vitamin C, fish oil, aminoacid, lemon grass (Cymbopogon citratus) and deionized water, the component of described antiallergic solution, by weight, comprising:
Konjacmannan 3-12 part, Radix Ophiopogonis polysaccharide 5-10 part,
Probiotic bacteria 10-20 part, vitamin C 8-16 part,
Fish oil 10-20 part, amino acid/11 2-25 part,
Lemon grass (Cymbopogon citratus) 15-20 part, deionized water 50-80 part.
The present invention also provides a kind of preparation method of baby wipes of daily antiallergic protection, it is characterized in that: comprise the following steps:
(1) by volume part is counted, and is dissolved in by the konjacmannan of 1 part in the weakly acidic solution of 50-80 part, and leave standstill 2-3h, carry out isolated by filtration after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution of konjac mannan;
(2) by Radix Ophiopogonis root surface impurity remove after, pulverizing and make powdery Radix Ophiopogonis, the water that the powdery of 1 weight portion is placed in 80-100 part Radix Ophiopogonis is boiled, reflux extraction, after concentrated, obtaining the aqueous solution containing selling winter polysaccharide;
(3) aqueous solution of the konjac mannan prepared by step (1) and step (2) prepare containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add probiotic bacteria, vitamin C, fish oil, aminoacid and deionized water successively, and regulate the pH value of solution to 6-6.5 with lemon grass (Cymbopogon citratus), continue to be stirred to evenly, obtain antiallergic solution.
Preferred as technique scheme, in described step (1), weakly acidic solution is acetum.
Preferred as technique scheme, in described step (1), isolated by filtration is that ultrafiltration membrance filter is separated.
Preferred as technique scheme, in described step (1), the solid content of the aqueous solution of konjac mannan is 43-52%.
Preferred as technique scheme, in described step (2), the particle diameter of powdery Radix Ophiopogonis is 5-10 μm.
Preferred as technique scheme, in described step (2), the time of boiling is 30-50min.
Preferred as technique scheme, in described step (2), the solid content containing the aqueous solution selling winter polysaccharide is 35-45%.
Preferred as technique scheme, in described step (3), the solid content of antiallergic solution is 30-45%.
Compared with prior art, the present invention has following beneficial effect:
(1) functional component in the antiallergic solution in the present invention is konjacmannan, Radix Ophiopogonis polysaccharide and probiotic bacteria, by the aqueous solution of konjacmannan through high temperature sterilize, prevent from mutually suppressing with probiotic bacteria, the mutual cooperation of three, anti-allergic effects is gentle, the surface with infant skin can be acted on for a long time, puzzlement is not caused to its skin.
(2) IgE antibody has crucial effect in I type anaphylaxis, IgE antibody is suppressed, and irritated symptom will alleviate, and konjacmannan can suppress the generation of IgE antibody, and the generation of IgA antibody and IgG antibody can be promoted, alleviate irritated symptom.Radix Ophiopogonis polysaccharide has antiinflammatory, antianaphylactic effect more, can treat the symptom such as inflammation, allergy that pathogenic microorganism causes.The antiallergic activity of probiotic bacteria is large, can improve the panimmunity power function of baby, improve its daily resistance for virus, and helps the various allergic symptom for the treatment of.
(3) the present invention also adopts the auxiliary agents such as vitamin C, fish oil, aminoacid, vitamin C can reduce the permeability of capillary tube, and possess slight anti-allergic effects, can prevent and auxiliary treatment dermatitis, fish oil can pin the moisture of the skin of baby, improve the immunity of skin, aminoacid can be moistened the skin of baby, the elasticity of maintenance baby skin.The auxiliary agent of function admirable that what the present invention selected is all, well can protect the skin of baby, and have certain auxiliary drug effect, uses the puzzlement that can not cause infant skin for a long time.
(4) the daily antiallergic protective liquid of baby wipes that prepared by the present invention adopts novel natural antibacterial active component as functional agent, and wetting agent, emollient and vitamin etc. that ilities is excellent, obtain antiallergic protection gentle, the protective liquid that baby can use for a long time, safe and effective, secure.
Detailed description of the invention:
Describe the present invention in detail below in conjunction with specific embodiment, be used for explaining the present invention in this illustrative examples of the present invention and explanation, but not as a limitation of the invention.
Embodiment 1:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 50 parts, leaves standstill 3h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 43%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 80 parts Radix Ophiopogonis is boiled 50min, reflux extraction, obtain after concentrated solid content be 35% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 6 parts and 12 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 10 parts, the vitamin C of 8 parts, the fish oil of 10 parts, the aminoacid of 12 parts and 40 parts successively, and regulate the pH value to 6.5 of solution with the lemon grass (Cymbopogon citratus) of 15 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 30%.
Embodiment 2:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 80 parts, leaves standstill 3h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 52%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 100 parts Radix Ophiopogonis is boiled 50min, reflux extraction, obtain after concentrated solid content be 45% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 25 parts and 27 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 20 parts, the vitamin C of 16 parts, the fish oil of 20 parts, the aminoacid of 25 parts and 60 parts successively, and regulate the pH value to 6 of solution with the lemon grass (Cymbopogon citratus) of 20 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 45%.
Embodiment 3:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 60 parts, leaves standstill 2.5h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 47%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 90 parts Radix Ophiopogonis is boiled 40min, reflux extraction, obtain after concentrated solid content be 38% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 12 parts and 15 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 12 parts, the vitamin C of 10 parts, the fish oil of 13 parts, the aminoacid of 15 parts and 50 parts successively, and regulate the pH value to 6.2 of solution with the lemon grass (Cymbopogon citratus) of 17 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 37%.
Embodiment 4:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 75 parts, leaves standstill 2.2h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 49%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 95 parts Radix Ophiopogonis is boiled 45min, reflux extraction, obtain after concentrated solid content be 30% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 20 parts and 20 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 15 parts, the vitamin C of 13 parts, the fish oil of 15 parts, the aminoacid of 20 parts and 55 parts successively, and regulate the pH value to 6.4 of solution with the lemon grass (Cymbopogon citratus) of 15 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 41%.
Embodiment 5:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 65 parts, leaves standstill 3h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 50%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 100 parts Radix Ophiopogonis is boiled 50min, reflux extraction, obtain after concentrated solid content be 42% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 18 parts and 20 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 15 parts, the vitamin C of 13 parts, the fish oil of 17 parts, the aminoacid of 19 parts and 55 parts successively, and regulate the pH value to 6.2 of solution with the lemon grass (Cymbopogon citratus) of 18 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 35%.
Embodiment 6:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 65 parts, leaves standstill 3h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 49%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 95 parts Radix Ophiopogonis is boiled 35min, reflux extraction, obtain after concentrated solid content be 40% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 19 parts and 20 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 18 parts, the vitamin C of 14 parts, the fish oil of 18 parts, the aminoacid of 19 parts and 50 parts successively, and regulate the pH value to 6.1 of solution with the lemon grass (Cymbopogon citratus) of 19 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 44%.
Embodiment 7:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 55 parts, leaves standstill 2h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 50%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 95 parts Radix Ophiopogonis is boiled 40min, reflux extraction, obtain after concentrated solid content be 40% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 12 parts and 17 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 17 parts, the vitamin C of 10 parts, the fish oil of 13 parts, the aminoacid of 18 parts and 50 parts successively, and regulate the pH value to 6.3 of solution with the lemon grass (Cymbopogon citratus) of 18 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 37%.
Embodiment 8:
(1) by volume part is counted, the konjacmannan of 1 part is dissolved in the acetum of 80 parts, leaves standstill 3h, be separated through ultrafiltration membrance filter after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution that solid content is the konjac mannan of 52%.
(2) by after the surface impurity removal of root Radix Ophiopogonis, pulverize and make the powdery Radix Ophiopogonis that particle diameter is 5-10 μm, the water that the powdery of 1 weight portion is placed in 80 parts Radix Ophiopogonis is boiled 30min, reflux extraction, obtain after concentrated solid content be 35% containing the aqueous solution selling winter polysaccharide.
(3) by weight, by the aqueous solution of the konjac mannan of 25 parts and 12 parts containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add the deionized water of the probiotic bacteria of 10 parts, the vitamin C of 8 parts, the fish oil of 10 parts, the aminoacid of 20 parts and 60 parts successively, and regulate the pH value to 6.5 of solution with the lemon grass (Cymbopogon citratus) of 15 parts, continue to be stirred to evenly, obtain the daily antiallergic protective liquid that solid content is the baby wipes of 43%.
After testing, the antianaphylactic result of the daily antiallergic protective liquid of baby wipes prepared of embodiment 1-6 is as follows:
As seen from the above table, the antiallergic activity of the daily antiallergic protective liquid of baby wipes prepared by the present invention is moderate, the gentle antiallergic of energy is described, and timeliness is longer, non-stimulated to infant skin.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.
Claims (9)
1. the daily antiallergic protective liquid of a baby wipes, it is characterized in that, described daily antiallergic protective liquid comprises konjacmannan, Radix Ophiopogonis polysaccharide, probiotic bacteria, vitamin C, fish oil, aminoacid, lemon grass (Cymbopogon citratus) and deionized water, the component of described antiallergic solution, by weight, comprising:
Konjacmannan 3-12 part, Radix Ophiopogonis polysaccharide 5-10 part,
Probiotic bacteria 10-20 part, vitamin C 8-16 part,
Fish oil 10-20 part, amino acid/11 2-25 part,
Lemon grass (Cymbopogon citratus) 15-20 part, deionized water 50-80 part.
2. a preparation method for the daily antiallergic protective liquid of baby wipes, is characterized in that: comprise the following steps:
(1) by volume part is counted, and is dissolved in by the konjacmannan of 1 part in the weakly acidic solution of 50-80 part, and leave standstill 2-3h, carry out isolated by filtration after making it fully swelling, get supernatant concentration, high temperature sterilize obtains the aqueous solution of konjac mannan;
(2) by Radix Ophiopogonis root surface impurity remove after, pulverizing and make powdery Radix Ophiopogonis, the water that the powdery of 1 weight portion is placed in 80-100 part Radix Ophiopogonis is boiled, reflux extraction, after concentrated, obtaining the aqueous solution containing selling winter polysaccharide;
(3) aqueous solution of the konjac mannan prepared by step (1) and step (2) prepare containing the aqueous solution of selling winter polysaccharide, heated and stirred, filter and remove impurity, after room temperature is down in sterilizing, add probiotic bacteria, vitamin C, fish oil, aminoacid and deionized water successively, and regulate the pH value of solution to 6-6.5 with lemon grass (Cymbopogon citratus), continue to be stirred to evenly, obtain the daily antiallergic protective liquid of baby wipes.
3. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, it is characterized in that: in described step (1), weakly acidic solution is acetum.
4. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, is characterized in that: in described step (1), and isolated by filtration is that ultrafiltration membrance filter is separated.
5. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, is characterized in that: in described step (1), the solid content of the aqueous solution of konjac mannan is 43-52%.
6. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, is characterized in that: in described step (2), and the particle diameter of powdery Radix Ophiopogonis is 5-10 μm.
7. the preparation method of the baby wipes of a kind of daily antiallergic protection according to claim 2, it is characterized in that: in described step (2), the time of boiling is 30-50min.
8. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, it is characterized in that: in described step (2), the solid content containing the aqueous solution selling winter polysaccharide is 35-45%.
9. the preparation method of the daily antiallergic protective liquid of a kind of baby wipes according to claim 2, is characterized in that: in described step (3), the solid content of the daily antiallergic protective liquid of baby wipes is 30-45%.
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