CN105496595A - Multifunctional experimental mouse operating device and operating method thereof - Google Patents

Multifunctional experimental mouse operating device and operating method thereof Download PDF

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Publication number
CN105496595A
CN105496595A CN201610001432.3A CN201610001432A CN105496595A CN 105496595 A CN105496595 A CN 105496595A CN 201610001432 A CN201610001432 A CN 201610001432A CN 105496595 A CN105496595 A CN 105496595A
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China
Prior art keywords
box
experimental mouse
top cover
operating means
multifunction
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201610001432.3A
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Chinese (zh)
Inventor
王政力
余加林
李禄全
杨亭
向青青
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Childrens Hospital of Chongqing Medical University
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Childrens Hospital of Chongqing Medical University
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Priority to CN201610001432.3A priority Critical patent/CN105496595A/en
Publication of CN105496595A publication Critical patent/CN105496595A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/006Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Husbandry (AREA)
  • Instructional Devices (AREA)

Abstract

The invention discloses a multifunctional experimental mouse operating device, comprising a cuboid-shaped box and a top cover, wherein one end surface of the cuboid-shaped box is an opening surface, and the other end surface is a blind end and is provided with a round tube communicating the inside and outside of the box; the bottom surface of the box, near the opening surface, is provided with a notch; the top surface of the box is semi-closed; and the top cover is movably connected with the box and can open or close the box. According to a multifunctional experimental mouse operating method disclosed by the invention, the multifunctional experimental mouse operating device is used, intraperitoneal injection, intraperitoneal anesthesia, atomizing operation, caudal vein blood sampling and tail fixation of an experimental mouse can be finished in the box in a closed state, the fixation and trachea medication of the experimental mouse can be finished in the box in an open state, and every operation can be finished by one person, so that the operation is simple, the experimental process is greatly simplified, and manpower is saved.

Description

A kind of Multifunction experimental mouse operating means and operational approach thereof
Technical field
The present invention relates to a kind of animal experiment device capable, particularly relate to a kind of Multifunction experimental mouse operating means.The invention still further relates to the operational approach of this device.
Background technology
Experimental mouse is laboratory animal the most frequently used in scientific experiments, needs experimental mouse to be fixed, anaesthetize before experimental implementation, then carries out the operations such as airway administration, atomization test, lumbar injection and tail vein blood.Because experimental mouse is agile, have sharp tooth, when implementing experiment, not only not easy to operate, part operation is difficult to single completing, and easily damages experimenter.At present, most experimental mouse operating means function singleness, complicated operation, is not easy to singlely complete experimental implementation.As publication number a kind of experimental rat holder disclosed in the patent of CN103815981A, publication number is experimental mouse lumbar injection holder disclosed in the patent of CN204274708U, all there is operation inconvenience, the single problem being difficult to related experiment, experimenter also faces the danger of being bitten by experimental mouse simultaneously, and can not complete the operations such as atomization, airway administration; Publication number is that a kind of experimental mouse that patent discloses of CN204192787U fills with lung fixed mount, and be an open fixed mount easily, function singleness, adopt rope to fix experimental mouse extremity, in practical operation, the used time is longer, and can not complete the operations such as atomization and lumbar injection.
Summary of the invention
The object of the present invention is to provide a kind of convenient operation and there is multi-functional experimental mouse operating means.
Second object of the present invention is the operational approach providing said apparatus.
The object of the present invention is achieved like this, a kind of Multifunction experimental mouse operating means, comprise cuboid box and top cover, one end face of cuboid box is opening surface, other end is cecum face and is provided with the pipe be communicated with inside and outside box, the bottom surface of box is provided with notch near opening surface place, and the end face of box is semiclosed, and top cover is flexibly connected with box and can opens or blind boxes.Box one end face opening of the present invention and end face is semiclosed, experimental mouse can be convenient to and initiatively creep into box or people for putting into, the other end is closed cecum face and is provided with the pipe connected inside and outside box, there is ventilatory function, and under box closed condition, nebulization catheter can be accessed, complete nebulisation operation, the notch arranged by bottom surface can complete lumbar injection to mouse and intraperitoneal anesthesia.
The enclosure portion of above-mentioned end face comprises " U " profile, and the tilting and low order end of " U " profile is positioned at above pipe and with the cecum face of box and is connected." U " profile is connected with box end face, makes cassette interior form the space diminished gradually, is convenient to the head of mouse to fix.
The position of above-mentioned notch corresponds to experimental mouse abdominal part, and centre is provided with tabula, spills to prevent experimental mouse limbs.
Above-mentioned top cover comprises main lid and two side covers, and two side covers are connected by keeper with main lid respectively and may be folded in main covering, and one end of main lid is flexibly connected with box by keeper, and the other end is provided with end cap and can the opening surface of blind boxes.
In order to allow to not malleable shape when holding device launches, above-mentioned all keepers are the tensioned keeper of band.
Above-mentioned end cap leaves an opening, the afterbody for experimental mouse stretches out, and is beneficial to carry out afterbody experimental implementation (as venous blood collection, experimental mouse are fixed).
It is 90 ° of angles that top cover is opened with box, two side covers are made to launch completely and keep shape by keeper, the area of top cover is double and shape is relatively fixing, tooth in experimental mouse is entangled by fine rule, hung on the suspension member of end cap, under self gravitation, make experimental mouse become vertical distraction state, contribute to airway open, four tablettings are utilized to be fixed experimental mouse extremity, experimenter is by the aid traction experimental mouse root of the tongue, can open airway completely, experimental implementation person can complete alone the operation of experimental mouse airway administration.
Second object of the present invention is achieved in that the operational approach of above-mentioned Multifunction experimental mouse operating means, comprises,
1) opening top cover, making experimental mouse initiatively creep into box or people for putting into by open end;
2) top closure box is put down;
3) by the pipe access nebulization catheter of box end face, nebulisation operation is completed;
4) experimental mouse lumbar injection or intraperitoneal anesthesia is completed by the notch of box bottom surface;
5) pass experimental mouse tail by the opening that box top cover is reserved, be beneficial to carry out tail vein
Blood sampling and afterbody are fixed.
6) open top cover, make top cover and box be 90 ° of angles, launch completely by making two side covers with tensioned keeper;
7) entangle tooth in experimental mouse by fine rule, hung on the suspension member of end cap.
8) with four tablettings, experimental mouse extremity are fixed;
9) operation of experimental mouse airway administration is completed.
The present invention has following beneficial effect:
1, the box one end face opening of Multifunction experimental mouse operating means of the present invention and end face is semiclosed, transparent materials is adopted to form dark situation, be conducive to experimental mouse and initiatively creep into box or people for putting into, the other end is closed cecum face and is provided with the pipe connected inside and outside box, there is ventilatory function, and under box closed condition, nebulization catheter can be accessed, complete nebulisation operation, the notch arranged by bottom surface can complete lumbar injection to mouse and intraperitoneal anesthesia, safe and reliable, overcome the problem of function singleness operator and experimental mouse is easily bitten that prior art exists.
2, the top cover of Multifunction experimental mouse operating means of the present invention is opened, top cover and box are 90 ° of angles, by with tensioned 4 keepers, two side covers are launched completely, the area of top cover is double and shape is relatively fixing, fine rule is placed on tooth in experimental mouse, by fine rule, mouse is hung on the suspension member of end cap, under self gravitation, make experimental mouse become vertical distraction state, air flue is opened, utilize four tablettings to be fixed experimental mouse extremity, experimenter, by the aid traction experimental mouse root of the tongue, can complete alone the operation of experimental mouse airway administration.
3, Multifunction experimental mouse operational approach of the present invention utilizes Multifunction experimental mouse operating means, can complete under box closed state and the lumbar injection of experimental mouse and intraperitoneal anesthesia, nebulisation operation, tail vein blood and afterbody are fixed, can complete the fixing of experimental mouse and airway administration in the on-state, and operations all can be completed by single, simple to operate, significantly simplify experimentation, and save manpower.
Accompanying drawing explanation
Fig. 1 is that schematic diagram opened by Multifunction experimental mouse operating means of the present invention;
Fig. 2 is the half-open schematic diagram of Multifunction experimental mouse operating means of the present invention;
Fig. 3 is that schematic diagram closed by Multifunction experimental mouse operating means of the present invention;
In figure, 1. box, 2. top cover, 2-1. side cover, 2-2. keeper, 2-3. end cap, 2-4. tabletting, 2-5. suspension member, the main lid of 2-6., 2-7. opening, 3. pipe, 4. notch, 5. end face, 6. " U " profile.
Detailed description of the invention
Embodiment, a kind of Multifunction experimental mouse operating means, comprise cuboid box 1 and top cover 2, one end face of cuboid box 1 is opening surface, other end is cecum face and is provided with the pipe 3 be communicated with inside and outside box 1, the bottom surface of box 1 is provided with notch 4 near opening surface place, and the end face 5 of box 1 is semiclosed, and top cover 2 and box 1 are flexibly connected by keeper 2-2 and can open or blind boxes 1.End face 5 enclosure portion comprises " U " profile 6, and the tilting and low order end of " U " profile 6 is positioned at above pipe 3 and with the cecum face of box 1 and is connected.The position of notch 4 corresponds to experimental mouse abdominal part, is provided with tabula in the middle of notch 4.Top cover 2 comprises a main lid 2-6 and two side cover 2-1, and two side cover 2-1 are connected by keeper 2-2 with the main 2-6 of lid respectively and may be folded in and mainly cover on 2-6, and one end of main lid 2-6 is provided with end cap 2-3 and can the opening surface of blind boxes 1, and end cap 2-3 is provided with opening 2-7.Two side cover 2-1 are respectively equipped with two tabletting 2-4, end cap 2-3 is provided with suspension member 2-5.Box 1 three side adopts light tight material, forms dark situation.Keeper 2-2 is with certain tension force, and side cover 2-1 can be kept to launch completely as shape during Fig. 1.
The operational approach of Multifunction experimental mouse operating means, comprises the steps:
1) opening top cover 2, making experimental mouse initiatively creep into box 1 or people for putting into box 1 by open end;
2) top cover 2 blind boxes 1 is put down;
3) access nebulization catheter by the pipe 3 of box 1 end face, complete nebulisation operation;
4) complete lumbar injection by the notch 4 of box 1 bottom surface, carry out lumbar injection or intraperitoneal anesthesia;
5) by the reserved opening 2-7 of end cap 2-3 through experimental mouse tail so that carry out tail vein blood and afterbody is fixed;
6) opening top cover 2, making top cover 2 and box 1 in 90 ° of angles, by making two side cover 2-6 launch completely with tensioned 4 keeper 2-2;
7) with fine rule, mouse is hung on the suspension member 2-5 of end cap 2-3;
8) with four tabletting 2-4, experimental mouse extremity are fixed;
9) experimenter's left hand is by the auxiliary appliance traction experimental mouse root of the tongue, and the right hand completes the operation of experimental mouse airway administration.
Multifunction experimental mouse operational approach of the present invention utilizes Multifunction experimental mouse operating means, can complete under box closed state and the lumbar injection of experimental mouse and intraperitoneal anesthesia, nebulisation operation, tail vein blood, afterbody are fixed, can complete the fixing of experimental mouse and airway administration in the on-state, and operations all can be completed by single, simple to operate, significantly simplify experimentation, and save manpower.

Claims (8)

1. a Multifunction experimental mouse operating means, it is characterized in that: comprise cuboid box (1) and top cover (2), one end face of described box (1) is opening surface, other end is cecum face and is provided with the pipe (3) be communicated with inside and outside box (1), the bottom surface of described box (1) is provided with notch (4) near opening surface place, the end face 5 of described box (1) is semiclosed, and described top cover (2) is flexibly connected with box (1) and can opens or blind boxes (1).
2. Multifunction experimental mouse operating means as claimed in claim 1, it is characterized in that: the enclosure portion of described end face (5) comprises " U " profile (6), described " U " profile (6) tilting and low order end is positioned at described pipe (3) top and is connected with the cecum face of box (1).
3. Multifunction experimental mouse operating means as claimed in claim 1 or 2, is characterized in that: the position of described notch (4) corresponds to experimental mouse abdominal part, is provided with tabula in the middle of described notch (4).
4. Multifunction experimental mouse operating means as claimed in claim 1 or 2, it is characterized in that: described top cover (2) comprises main lid (2-6) and two side covers (2-1), described two side covers (2-1) are connected by keeper (2-2) with main lid (2-6) respectively and may be folded on main lid (2-6), one end of described main lid (2-6) is flexibly connected with box (1) by keeper (2-2), and the other end is provided with end cap (2-3) and can the opening surface of blind boxes (1).
5. Multifunction experimental mouse operating means as claimed in claim 4, is characterized in that: described keeper (2-2) is the tensioned keeper of band.
6. Multifunction experimental mouse operating means as claimed in claim 1 or 2, is characterized in that: described end cap (2-3) leaves an opening (2-7).
7. Multifunction experimental mouse operating means as claimed in claim 4, is characterized in that: described two side covers (2-1) are respectively equipped with two tablettings (2-4), and described end cap (2-3) is provided with suspension member (2-5).
8. the operational approach of the Multifunction experimental mouse operating means as described in any one of claim 1-7, is characterized in that: comprise,
1) opening top cover (2), making experimental mouse initiatively creep into box (1) or people for putting into box (1) by open end;
2) top cover (2) blind boxes (1) is put down;
3) by pipe (3) the access nebulization catheter of box (1) end face, under box (1) closed condition, nebulisation operation is completed;
4) by the notch (4) of box (1) bottom surface, under box (1) closed condition, lumbar injection and the intraperitoneal anesthesia of experimental mouse is completed;
5) by the reserved opening (2-7) of box top cover through experimental mouse tail, be beneficial to carry out tail vein blood and afterbody is fixed;
6) open top cover (2), make top cover (2) and box (1) in 90 ° of angles, by keeper (2-2), two side covers (2-1) are launched completely;
7) entangle tooth in experimental mouse with fine rule, hung by the suspension member (2-5) of end cap (2-3);
8) with four tablettings (2-4), experimental mouse extremity are fixed;
9) operation of experimental mouse airway administration is completed.
CN201610001432.3A 2016-01-05 2016-01-05 Multifunctional experimental mouse operating device and operating method thereof Pending CN105496595A (en)

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CN201610001432.3A CN105496595A (en) 2016-01-05 2016-01-05 Multifunctional experimental mouse operating device and operating method thereof

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Application Number Priority Date Filing Date Title
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CN105496595A true CN105496595A (en) 2016-04-20

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106725980A (en) * 2016-12-30 2017-05-31 谷翠芝 Rat Thoracicoabdominal puncture fixing device
CN107041795A (en) * 2017-04-14 2017-08-15 楚雄医药高等专科学校 A kind of laboratory mice fixing device
CN108992198A (en) * 2018-06-23 2018-12-14 西昌学院 Small white mouse tail vein injection fixator
CN110772351A (en) * 2019-11-13 2020-02-11 重庆医药高等专科学校 Mouse experimental device

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CN2035224U (en) * 1988-07-09 1989-04-05 中国人民解放军空军衡阳医院 Box for fettering baoding rat
JPH0847502A (en) * 1994-08-09 1996-02-20 Tsumura & Co Retainer
CN201008588Y (en) * 2007-02-02 2008-01-23 中南大学 Safe operation case for long tail animal experiment
CN202342228U (en) * 2011-12-12 2012-07-25 佳木斯大学 Rat fixing box
CN203943763U (en) * 2014-07-04 2014-11-19 中国人民解放军第三军医大学野战外科研究所 Rat hindlimb motion restriction means
CN204521045U (en) * 2015-04-07 2015-08-05 中国农业科学院兰州畜牧与兽药研究所 A kind of large mouse fixing for the test of tail vein
CN204618469U (en) * 2015-02-15 2015-09-09 重庆医科大学附属儿童医院 Experimental mouse injection auxiliary fixer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2035224U (en) * 1988-07-09 1989-04-05 中国人民解放军空军衡阳医院 Box for fettering baoding rat
JPH0847502A (en) * 1994-08-09 1996-02-20 Tsumura & Co Retainer
CN201008588Y (en) * 2007-02-02 2008-01-23 中南大学 Safe operation case for long tail animal experiment
CN202342228U (en) * 2011-12-12 2012-07-25 佳木斯大学 Rat fixing box
CN203943763U (en) * 2014-07-04 2014-11-19 中国人民解放军第三军医大学野战外科研究所 Rat hindlimb motion restriction means
CN204618469U (en) * 2015-02-15 2015-09-09 重庆医科大学附属儿童医院 Experimental mouse injection auxiliary fixer
CN204521045U (en) * 2015-04-07 2015-08-05 中国农业科学院兰州畜牧与兽药研究所 A kind of large mouse fixing for the test of tail vein

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106725980A (en) * 2016-12-30 2017-05-31 谷翠芝 Rat Thoracicoabdominal puncture fixing device
CN107041795A (en) * 2017-04-14 2017-08-15 楚雄医药高等专科学校 A kind of laboratory mice fixing device
CN107041795B (en) * 2017-04-14 2018-09-21 楚雄医药高等专科学校 A kind of laboratory mice fixing device
CN108992198A (en) * 2018-06-23 2018-12-14 西昌学院 Small white mouse tail vein injection fixator
CN110772351A (en) * 2019-11-13 2020-02-11 重庆医药高等专科学校 Mouse experimental device

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Application publication date: 20160420