CN105433930B - Optical fiber pressure measuring device for venous blood pressure measurement - Google Patents
Optical fiber pressure measuring device for venous blood pressure measurement Download PDFInfo
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- CN105433930B CN105433930B CN201511033006.XA CN201511033006A CN105433930B CN 105433930 B CN105433930 B CN 105433930B CN 201511033006 A CN201511033006 A CN 201511033006A CN 105433930 B CN105433930 B CN 105433930B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
- A61B5/02152—Measuring pressure in heart or blood vessels by means inserted into the body specially adapted for venous pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
- A61B5/02154—Measuring pressure in heart or blood vessels by means inserted into the body by optical transmission
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4244—Evaluating particular parts, e.g. particular organs liver
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0252—Load cells
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Abstract
The invention discloses an optical fiber pressure measuring device for measuring venous blood pressure, which comprises a pressure measuring probe and a detection catheter; the pressure measuring probe comprises a probe barrel, a membrane sleeve, a sealing ring, a sealing membrane and a conducting medium, wherein the membrane sleeve is of a barrel-shaped structure with one open end, the open end of the membrane sleeve is sleeved on the probe barrel, a section of hollow part is arranged on the side surface of the membrane sleeve and the sealing membrane is arranged to seal the membrane sleeve, the sealing ring is arranged in the probe barrel, and the probe barrel, the membrane sleeve and the sealing ring form a closed space and are filled with the conducting medium; the detection conduit comprises a connecting cylinder, a conduction sleeve, a lining and an optical fiber, wherein the conduction sleeve is assembled at the front end of the connecting cylinder, the lining is assembled at the rear end of the connecting cylinder, the optical fiber sequentially penetrates through the lining, the connecting cylinder and the conduction sleeve, the extending part of the optical fiber is used as a sensor, the detection conduit is inserted into a pressure measuring probe, and part of the optical fiber used as the sensor extends into a closed space where a conduction medium is located. The invention has the advantages of improving the detection precision of the measuring probe in clinical application and preventing cross infection caused by the repeated use of the measuring probe.
Description
Technical Field
The invention relates to a pressure measuring device, in particular to an optical fiber pressure measuring device for measuring venous blood pressure.
Background
In clinical medicine, the accurate measurement of the blood pressure of the internal circulation vein has great significance for the diagnosis and treatment of diseases and the pathological research.
Modern medicine considers that cirrhosis is a major complication of hepatitis virus infected persons and liver disease patients, and the consequences of cirrhosis are necessarily abnormal increase of portal blood pressure, thereby causing esophageal varices and sudden high-risk bleeding. The esophageal venous blood pressure and the portal venous blood pressure and the hepatic venous pressure gradient value are in a straight line correlation rule, and measuring the esophageal venous blood pressure is an effective means for monitoring and judging bleeding precursors of patients clinically. Clinically, the method becomes an important means for auxiliary diagnosis and treatment monitoring by detecting esophageal venous pressure.
At present, venous manometry generally needs to be completed by means of an endoscope, and as the content of in vivo exploration subjects, the clinical application mainly comprises two forms of intravenous manometry and intravenous manometry, wherein the former measures blood pressure by puncturing varicose veins through a fine needle, and the latter measures esophageal varicose vein blood pressure by touch. Puncture measurements are prone to bleeding and infection and have been used very rarely in the clinic; there are several methods for touch measurement, and a catheter communication detection method and a balloon observation detection method are commonly used.
The optical fiber pressure sensing detection is a novel non-invasive venous blood pressure measuring method, and is currently in clinical medical application, wherein a vein pressure measuring instrument for realizing detection by adopting a photoelectric measurement principle and an application of adopting an optical fiber sensor as a measuring probe are new technologies.
In the patent technology which the inventor has applied, the invention patent of venous blood pressure measuring probe for medical clinical application, ZL 201220232221; the invention patent of an intravenous blood pressure measuring probe and an installation method and a use method thereof, 2012101605500, has already fully explained the design of the related intravenous pressure measuring instrument. However, the measuring probe used for measuring and collecting pressure signals is a weak link of the whole application system, is limited by the composition material structure and process conditions, has short service life, low measuring precision, difficult post-maintenance and the like, and restricts the large-scale manufacturing process.
Disclosure of Invention
The invention aims to provide an optical fiber pressure measuring device for measuring venous blood pressure, which aims to improve the detection precision of a measuring probe in clinical application and prevent cross infection caused by repeated use of the measuring probe.
The invention is realized by the following technical scheme.
An optical fiber pressure measuring device for measuring venous blood pressure comprises a pressure measuring probe and a detection catheter;
the pressure measuring probe comprises a probe barrel, a membrane sleeve, a sealing ring, a sealing membrane and a conducting medium, wherein the membrane sleeve is of a barrel-shaped structure with one open end, the open end of the membrane sleeve is sleeved on the probe barrel, a section of hollow part is arranged on the side surface of the membrane sleeve and is sealed by the sealing membrane, the sealing ring is arranged in the probe barrel, and the probe barrel, the membrane sleeve and the sealing ring form a closed space and are filled with the conducting medium;
the detection conduit comprises a connecting cylinder, a conduction sleeve, a lining and an optical fiber, wherein the conduction sleeve is assembled at the front end of the connecting cylinder, the lining is assembled at the rear end of the connecting cylinder, the optical fiber sequentially penetrates through the lining, the connecting cylinder and the conduction sleeve, the extending part serves as a sensor, the detection conduit is inserted into the pressure measuring probe, and part of the optical fiber serving as the sensor extends into a closed space where a conduction medium is located.
Wherein, above-mentioned membrane cover is the wedge to the side slope that has above-mentioned sealing membrane, above-mentioned membrane cover is by its diameter crescent of front end to the terminal of above-mentioned sealing membrane, so that when probe cylinder and examined blood vessel cylinder had the contained angle, it can still form parallel with the blood vessel cylinder and touch to survey the membrane, ensures that blood flow pressure does not have blind area conduction.
Furthermore, the probe cylinder is of a cylindrical structure with a conical front end opening and a sealed rear end, and the longer front end of the probe cylinder extends into the side face of the membrane sleeve with the sealing membrane.
Furthermore, the probing cylinder is provided with a circle of inward grooves, and the diameter of the probing cylinder limited by the inward grooves is used for limiting the sealing ring.
Furthermore, the probe cylinder is provided with an inward concave point, the connecting cylinder is provided with a circle of groove matched with the inward concave point, and the inward concave point and the groove limit the connecting cylinder together.
Further, the diameter of the conductive sleeve is smaller than that of the connecting cylinder, and the conductive sleeve is fitted into the front end of the connecting cylinder and is retained by the recess of the connecting cylinder.
Further, a socket is provided at a rear end of the connecting cylinder, and the connecting cylinder is inserted into the bushing through the socket.
Furthermore, a spiral duct is sleeved outside the socket of the connecting cylinder and the bush.
The invention has the beneficial effects that:
when in use, the measuring probe is arranged at the front end of a detection catheter of the vein pressure meter and is combined with the detection catheter to form a touch pressure meter, the measuring probe is implanted into a body through the guidance of an endoscope and is positioned on the surface of a vein needing to be detected for measurement, (for example, when the vein pressure of a patient with esophageal varices is measured, the gastroscope is firstly used for detecting and determining the position of a detected blood vessel, then the detection catheter provided with the pressure measuring probe is guided into the surface of the detected blood vessel through an endoscope biopsy hole, touch detection operation is carried out for a plurality of seconds, and the measurement operation is finished after the data or the graph reported by a display terminal of the vein pressure meter tend to be stable.)
The detection method disclosed adopts an integrated structure of a measuring probe and a detection catheter, the probe is directly encapsulated at the front end of the catheter, and the detection membrane surface of the probe is parallel to the axis of a probe cylinder. In practical use, due to the restriction of the inherent structure of the endoscope, an included angle exists between the detection membrane surface of the probe and the cylindrical surface of the blood vessel to be detected, and a touch blind area (an area where two curved surfaces are not touched) is easily generated when the two curved surfaces are touched with each other, so that the blood flow pressure in the blood vessel cannot be completely transmitted to and sensed by the detection membrane surface of the probe, and the detection precision is influenced. The invention adopts the wedge-shaped detection membrane sleeve, namely an inclined detection membrane surface is formed at an included angle formed between one side of the membrane sleeve and the axis of the membrane sleeve, so that the detection membrane can still be in parallel contact with the cylindrical surface of the blood vessel when the cylindrical surface of the probe and the cylindrical surface of the blood vessel to be detected have included angles, and the conduction of blood pressure without blind areas is ensured.
As a pressure measuring instrument matched with an endoscope for use, the pressure measuring instrument is a system device which is repeatedly applied, and because the use process is polluted by secretion and physiological tissues in a patient body, strict cleaning and disinfection are required after each case of exploration, the operation is not only strict and complicated, but also the detection membrane surface of a probe is extremely easy to damage, so that the failure of a sensing unit is caused. The measuring probe designed by the invention is a simple disposable device, and sealed storage is realized by filling a conducting medium in advance, sterilizing and treating. When in use, the probe is tightly connected with the detection conduit through the rapid insertion operation, and the probe is rapidly combined into a touch pressure measuring instrument; after the probe is used, only the contaminated measuring probe needs to be removed, and the cleaning and disinfection process of the probe is avoided (the detection catheter part above the probe is always positioned in the biopsy hole of the endoscope in the using process, so the degree of contamination in the body is low, the corresponding cleaning and disinfection operation is relatively simple, and special maintenance measures do not need to be taken on the detection membrane surface).
Drawings
FIG. 1 is a disassembled view of the whole structure of the optical fiber pressure measuring device of the present invention;
FIG. 2 is a schematic view of the pressure probe of the present invention;
FIG. 3 is a schematic diagram of a probing catheter according to the present invention.
Detailed Description
The invention is explained in more detail below with reference to the figures and examples.
Fig. 1 is a disassembled view of the whole structure of the optical fiber pressure measuring device of the invention, fig. 2 is a structural schematic view of the pressure measuring probe of the invention, FIG. 3 is a schematic structural view of the probing catheter of the present invention, referring to FIGS. 1-3, the pressure measuring probe of the present invention comprises a probe barrel 1-1, a membrane sleeve 1-2, a sealing ring 1-3, a sealing membrane 1-4, and a conducting medium 1-5, wherein the membrane sleeve 1-2 is a cylindrical structure with an open end, the opening end of the probe tube is sleeved with the probe tube 1-1, the side surface of the membrane sleeve 1-2 is provided with a section of hollow and is sealed by arranging the sealing membrane 1-4, the sealing ring 1-3 is arranged in the probe tube 1-1, and the probe tube 1-1, the membrane sleeve 1-2 and the sealing ring 1-3 form a closed space and are filled with the conducting medium 1-5.
The detection conduit comprises a connecting cylinder 2-1, a conducting sleeve 2-2, a lining 2-3 and an optical fiber 2-4, wherein the conducting sleeve 2-2 is assembled at the front end of the connecting cylinder 2-1, the lining 2-3 is assembled at the rear end of the connecting cylinder 2-1, the optical fiber 2-4 sequentially penetrates through the lining 2-3, the connecting cylinder 2-1 and the conducting sleeve 2-2, the extending part is used as a sensor, the detection conduit is inserted into the pressure measuring probe, and part of the optical fiber used as the sensor extends into a closed space where a conducting medium is located.
The film sleeve 1-2 is wedge-shaped, and has a side surface inclined with respect to the sealing film 1-4, and the diameter of the film sleeve 1-2 is gradually increased from the front end to the end of the sealing film 1-4.
The probe 1-1 is a cylinder structure with a conical front end opening and a sealed rear end, and the longer front end of the probe 1-1 extends into the side surface of the membrane sleeve 1-2 with the sealing membrane 1-4.
The probe cylinder 1-1 is provided with a circle of inward grooves 1-11, and the diameter of the probe cylinder 1-1 limited by the inward grooves 1-11 is used for limiting the sealing ring 1-3.
The probe cylinder 1-1 is provided with an inward concave point 1-12, the connecting cylinder 2-1 is provided with a circle of groove 2-11 matched with the inward concave point 1-12, and the inward concave point 1-12 and the groove 2-11 limit the connecting cylinder 2-1 together.
The diameter of the conduction sleeve 2-2 is smaller than that of the connecting cylinder 2-1, and the conduction sleeve 2-2 is fitted into the front end of the connecting cylinder 2-1 and is limited by the groove 2-11 of the connecting cylinder 2-1.
The rear end of the connecting cylinder 2-1 is provided with a socket 2-12, and the connecting cylinder 2-1 is inserted into the bush 2-3 through the socket 2-12.
The socket 2-12 of the connecting cylinder 2-1 and the bush 2-3 are sleeved with a spiral duct 2-5.
The pressure measuring probe is a sensing component of the optical fiber pressure sensor, is mainly formed by precisely processing and packaging materials such as titanium-aluminum alloy, iron-chromium-nickel alloy, Polyurethane (Polyurethane), natural rubber, Polyamide (PA) and the like, and is a disposable consumption device in the application process of the pressure measuring instrument.
The pressure measuring probe is a micro column body, the diameter of the section of the column body is less than 2mm, and the length of the main body is less than 25 mm.
The material of the probe 1-1 is ultra-thin stainless steel, a semi-closed cylinder with one conical end is formed by cold punching, an inward groove 1-11 and an inward concave point 1-12 are respectively formed at two set positions at the middle section by rolling along the circumference, a plane notch is formed at one side of the conical end and the central axis of the cylinder by grinding, and the notch is covered by a film sleeve 1-2 to form a conductive film surface of the measuring probe.
The inward grooves 1-11 are used as positioning and fixing supports for the sealing rings 1-3 respectively; used for the termination positioning of the plugging detection conduit.
The membrane sleeve 1-2 is formed by adopting natural rubber emulsion injection molding, is sleeved at the conical end of the probe tube 1-1 during installation, is tightly combined with the elastic tension of the membrane sleeve through a slow release adhesive pre-coated between the membrane sleeve 1-2 and the joint surface of the probe tube 1-1, and forms a wedge-shaped conductive membrane surface on the notch plane of the probe tube.
The sealing ring 1-3 is made of high molecular elastic material by injection molding, is implanted into the probe through the incision of the probe 1-1 and is fixed and fixed at a set position by pre-coating adhesive (the manufacturing step must be completed before the installation of the membrane sleeve), and the function of the sealing ring is to prevent the liquid conducting medium 1-5 filled in the probe from leaking or volatilizing. The inner holes of the sealing rings 1-3 are reserved as the optical fiber sensor channel in the plugging detection guide pipe, liquid conducting medium is injected into the inner hole of the sealing ring during manufacturing, then a sealing plug made of the same material as the sealing ring is used for blocking the inner hole of the sealing ring, the conducting medium is prevented from overflowing, and the sealing plug can be pulled out until the sealing ring is used and installed.
The detection conduit is a conduction device for connecting the whole instrument and the pressure measuring probe, and the optical fiber 2 (as a part of the pressure sensor) and the optical fiber (as a conduction part) thereof are implanted by adopting the elastic spiral sleeves 2-5 and then are packaged by hot melting welding. Because the detecting conduit is frequently inserted, pulled out, twisted and stretched when in use, the detecting conduit is easy to be fatigued, has only limited service life and belongs to a matched vulnerable device.
A connector device for collecting and transmitting optical signals. The service life is designed to be 6000 times or 12 working months, and the device is a vulnerable device which needs to be maintained or replaced regularly.
And a detection component for sensing the pressure signal and converting the pressure signal into an optical signal. The material is made of titanium-aluminum alloy, iron-chromium-nickel alloy, Polyurethane (Polyurethane), Polyamide (PA) natural rubber and the like through precision machining and aseptic packaging, and belongs to disposable consumption equipment.
The above embodiments are only for illustrating the technical idea and features of the present invention, and the purpose of the present invention is to enable those skilled in the art to understand the content of the present invention and implement the present invention, and not to limit the protection scope of the present invention by this. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.
Claims (7)
1. An optical fiber pressure measuring device for measuring venous blood pressure is characterized by comprising a pressure measuring probe and a detection catheter;
the pressure measuring probe comprises a probe cylinder, a membrane sleeve, a sealing ring, a sealing membrane and a conducting medium, wherein the membrane sleeve is of a cylindrical structure with an opening at one end, the opening end of the membrane sleeve is sleeved on the probe cylinder, a section of hollow part is arranged on the side surface of the membrane sleeve and is provided with the sealing membrane for sealing the membrane sleeve, the sealing ring is arranged in the probe cylinder, and the probe cylinder, the membrane sleeve and the sealing ring form a closed space and are filled with the conducting medium;
the detection conduit comprises a connecting cylinder, a conduction sleeve, a bushing and an optical fiber, wherein the conduction sleeve is assembled at the front end of the connecting cylinder, the bushing is assembled at the rear end of the connecting cylinder, the optical fiber sequentially penetrates through the bushing, the connecting cylinder and the conduction sleeve, the extending part of the optical fiber is used as a sensor, the detection conduit is inserted into the pressure measuring probe, and part of the optical fiber used as the sensor extends into a closed space where a conduction medium is located;
the membrane cover is the wedge, and has the side slope of seal membrane, the membrane cover is by the front end extremely its diameter of end of seal membrane crescent to when making probe cylinder and examined blood vessel cylinder have the contained angle, survey the membrane and still can form parallel with the blood vessel cylinder and touch, guarantee blood flow pressure non-blind area conduction.
2. The optical fiber pressure measuring device for measuring venous blood pressure as claimed in claim 1, wherein the probe tube is a tube structure with a tapered front end opening and a sealed rear end, and the longer front end of the probe tube extends into the side surface of the membrane sleeve with the sealing membrane.
3. The optical fiber pressure measuring device for venous blood pressure measurement according to claim 1, wherein the probe barrel is provided with a circle of inward grooves, and the diameter of the probe barrel limited by the inward grooves is used for limiting the sealing ring.
4. The optical fiber pressure measuring device for venous blood pressure measurement according to claim 1, wherein the probe cylinder is provided with an inward concave point, the connecting cylinder is provided with a circle of groove matching with the inward concave point, and the inward concave point and the groove jointly limit the connecting cylinder.
5. The fiber optic pressure measurement device according to claim 4, wherein the conductive sleeve has a smaller diameter than the connector barrel, fits into the front end of the connector barrel and is retained by the recess of the connector barrel.
6. The fiber optic pressure measurement device according to claim 1, wherein the rear end of the connector barrel is provided with a socket through which the connector barrel is inserted into the bushing.
7. The optical fiber pressure measuring device for venous blood pressure measurement according to claim 1, wherein a spiral conduit is provided to the socket of the connection cylinder and the bush in a sleeved manner.
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CN102908133A (en) * | 2012-11-12 | 2013-02-06 | 合肥优尔电子科技有限公司 | Esophagus vein blood pressure measuring instrument |
CN103976722A (en) * | 2014-05-26 | 2014-08-13 | 中南大学湘雅三医院 | Non-invasive pressure measuring method for esophageal varices |
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US9241641B2 (en) * | 2012-07-20 | 2016-01-26 | Acist Medical Systems, Inc. | Fiber optic sensor assembly for sensor delivery device |
US20150173629A1 (en) * | 2013-12-19 | 2015-06-25 | Volcano Corporation | Device, system, and method for assessing intravascular pressure |
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US6485428B1 (en) * | 1998-04-21 | 2002-11-26 | Dietmar Enk | Apparatus for and method of intravasal pressure measurement and low-contamination insertion of catheters for example into blood vessels |
CN102908133A (en) * | 2012-11-12 | 2013-02-06 | 合肥优尔电子科技有限公司 | Esophagus vein blood pressure measuring instrument |
CN103976722A (en) * | 2014-05-26 | 2014-08-13 | 中南大学湘雅三医院 | Non-invasive pressure measuring method for esophageal varices |
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A pressure sensor using tapered optical fiber and curved polymer films;X.Dai et al;《Photonics North 2011》;20110908;全文 * |
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