CN105411584A - Scalp EEG collection system with central wetting function and flexible micro-seepage electrode structure - Google Patents

Scalp EEG collection system with central wetting function and flexible micro-seepage electrode structure Download PDF

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Publication number
CN105411584A
CN105411584A CN201511020694.6A CN201511020694A CN105411584A CN 105411584 A CN105411584 A CN 105411584A CN 201511020694 A CN201511020694 A CN 201511020694A CN 105411584 A CN105411584 A CN 105411584A
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micro
electrode
flexible
flexible hose
oozes
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CN105411584B (en
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裴为华
邢潇
郭旭宏
陈弘达
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Institute of Semiconductors of CAS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/291Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • A61B5/6803Head-worn items, e.g. helmets, masks, headphones or goggles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • A61B2562/125Manufacturing methods specially adapted for producing sensors for in-vivo measurements characterised by the manufacture of electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/22Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
    • A61B2562/221Arrangements of sensors with cables or leads, e.g. cable harnesses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The invention discloses a flexible micro-seepage electrode which comprises a flexible hose (21), a micro-seepage contact head (22) and a conductive lead (23), wherein the flexible hose (21) comprises a front end and a rear end; the front end is connected with the micro-seepage contact head (22); the rear end is connected with a liquid bag for storing a conducting solution; the flexible hose (21) is fully filled with the conducting solution; the conductive lead (23) is immersed in the conducting solution. The invention further discloses a scalp EEG collection system using the electrode, the formed flexible micro-seepage electrode and the scalp EEG collection system have good impedance characteristic and comfort degree, uncomfortableness caused by a good deal of conducting solution residual is avoided, and the experimental preparation time is further greatly reduced.

Description

The brain electricity cap that a kind of concentrated confession is wet and flexiblely micro-ly ooze electrode structure
Technical field
The present invention relates to the correlative technology field such as micro Process manufacturing technology and electricity physiological signal collection, be specifically related to a kind of concentrated for wet electrode structure and the brain electricity cap that forms based on metal and flexible material.
Background technology
Scalp eeg collection system is commonly referred to brain electricity cap.Brain electricity cap is a kind ofly assembled with electrode for encephalograms and electrode for encephalograms firmly can be attached to the device of head and immediate vicinity.Under normal circumstances, after brain electricity cap is worn, in order to make to form well stable electrical contact between electrode and scalp, needing by hole reserved on brain electricity cap and electrode, injecting the conductive paste comprising specific ion and conductive characteristic, there is proper viscosity simultaneously one by one to base part.Overflow to surrounding to prevent conductive paste, general electrode is all designed to tubbiness or bowl-shape, the electrode cream injected is filled between scalp and electrode, plays wet skin and eliminates the electric isolution that causes of hair, for brain wave acquisition provides a lower electrode/organizational interface.Up to now, this electrode structure and cooperation conductive paste lay a kind of eeg signal acquisition device that strategy is signal quality the best always.
Although take advantage in electrical signal collection quality, mainly there are three aspects in the shortcoming of this electrode: one is use time long, and need electrode injection conductive paste one by one, a people is difficult to complete separately wearing of electrode; Second is after experimenter uses this electrode, and hair and scalp sites have serious conducting resinl and remain, and need hair washing to remove, cause very large inconvenience to user.3rd is be not suitable for long-term chronic electricity physiological signal monitoring.Along with passage of time, conductive liquid can volatilization gradually, evaporation, increase skin electrode interface impedance.Along with the expansion and deeply of brain electricity application in health supervision and brain-computer interface, the deficiency of the mode of this electrode+conductive paste more and more highlights.In these application scenarios, in order to self-health supervision or amusement, user be difficult to tolerate with this other people lay, by the operator scheme of rear hair washing.Some mechanisms have developed the dry electrode not needing conductive paste for this reason, " DryEEGElectrodes " one delivered on SENSORS periodical for 2014 as people such as M.A.Lopez-Gordo is in literary composition, to main dry electrode company and product were summarized and summed up in recent years, these dry electrode devices, no matter in comfort or in signal quality, all cannot be compared with wet electrode.In order to eliminate the obstruct of hair, dry electrode device mostly adopts pectinate texture, comb is utilized to pass hair, while having lacked conductive paste buffering, the cross section that comb is less directly contacts scalp inherently certain discomfort, simultaneously in order to make contact more stable, need to apply larger pressure on the dry electrode of pectination toward contact.In impedance and signal stabilization, owing to lacking the buffering of conductive paste, dry electrode device is often very responsive to motion artifacts, and this is very disadvantageous to having the system of dressing requirement.Find in long-term research, it is really up to the mark to there is hardness in the dry electrode overwhelming majority that metal electrode or other polymeric materials are formed, and wears the phenomenons such as uncomfortable simultaneously, when being especially for use in human brain experiment, brings pain to a certain degree to experimenter.
Summary of the invention
(1) technical problem that will solve
For existing dry, wet electrode in problems such as comfort level, Preparatory work of experiment overlong time, long term monitoring and skin electrode interface impedance are unstable.Main purpose of the present invention is to provide a kind of brain electricity cap be made up of as main body flexible material, realizes the brain wave acquisition comfortable fast namely worn namely.
(2) technical scheme
According to an aspect of the present invention, provide and a kind of flexible micro-ly ooze electrode, it comprises flexible hose, micro-ly oozes contact head and conductive lead wire, flexible hose comprises front-end and back-end, front end is connected with micro-contact head that oozes, rear end is connected with the liquid capsule storing conductive liquid, and be full of conducting liquid in flexible hose, conductive lead wire is immersed in this conducting solution.
According to a further aspect in the invention, provide the brain electricity cap that a kind of concentrated confession is wet, it comprises liquid capsule and flexibility is micro-oozes electrode, liquid capsule is arranged on brain electricity cap, store to make flexible micro-container oozing the conductive liquid of electrode moistening on brain electricity cap, flexible micro-electrode that oozes comprises flexible hose, micro-ly oozes contact head and conductive lead wire, flexible hose comprises front-end and back-end, front end is connected with micro-contact head that oozes, rear end is connected with the liquid capsule storing conductive liquid, be full of conducting liquid in flexible hose, conductive lead wire is immersed in this conducting solution.
(3) beneficial effect
As can be seen from technique scheme, what the present invention adopted is be main body by a kind of flexible material, and what formed in conjunction with conducting objects possesses the electric cap system of the brain storing quantitative conductive liquid simultaneously.The flexibility formed is micro-oozes electrode and brain electricity cap has good impedance operator and comfort level, and people can not be made to produce pain and the conductive liquid residual sense of discomfort caused in a large number of electrode compressing.Along with the optimum supply of conductive liquid, maintain the stability of impedance between skin electrode, drastically increase the quality of bio-electro-physiologic signal, be beneficial to and for a long time brain signal monitored.Show in a large amount of tests, the brain electricity cap that the concentrated confession that the present invention is formed is wet and flexible micro-electrode structure that oozes are tested respond well, can reach the collection effect similar to traditional brain electricity cap, demonstrate feasibility of the present invention.
Accompanying drawing explanation
Fig. 1 is that the present invention concentrates for wet brain electricity cap system schematic;
To be that flexibility of the present invention is micro-ooze electrode structure schematic diagram to Fig. 2.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly understand, below in conjunction with specific embodiment, and with reference to accompanying drawing, the present invention is described in more detail.
The present invention proposes the micro-brain electricity cap oozing electrode and use the concentrated confession of this electrode wet of a kind of flexibility.According to ultimate principle of the present invention, flexible micro-electrode that oozes is made up of flexible hose, flexible hole gap material and conductive lead wire.Conducting liquid is full of in flexible hose, its front end is flexible hole gap material (as fiber or flexible ceramic), rear end is connected to the liquid capsule of perfusion conductive liquid, the lead riser of conductive lead wire adopts silver/silver chloride preparation, rear end is connected with connecting line, wherein silver/silver chloride part is immersed in the liquid of flexible pipe, with hole neighbour; Connecting line passes through hose wall, is in outside flexible pipe.Conductive liquid can pass through hole, penetrates into front aperture gap material lower surface with capillarity, and when the surface tension of conductive liquid in porous material and osmotic pressure reach balance, conductive liquid reaches capacity on surface, now no longer includes conductive liquid and oozes out; When the surface of porous material is broken because of the reason consumption such as evaporation, balance, the solution in flexible pipe can continue to add to lower surface, and holding electrode and the scalp contacted thereof are in moistening and low resistive state.Be assemblied in same brain electricity cap on this electrode by hose connection to a liquid capsule.It is constant that the maximum feature of the present invention is to keep impedance stabilization for a long time, and comfort is high, disposablely pours into all electrodes simultaneously, considerably reduces electrode time, namely wear and namely use.Owing to adopting micro-mode of oozing, avoid the adhesion of conductive paste on hair.Such electrode and both there is the good advantage of wet electrode signal to noise ratio, overcome again wet electrode lay time long, wear after need to remove the inconvenience such as the conductive paste on hair.
The solution of the present invention is further described referring to Fig. 1 and Fig. 2.Fig. 1 is that the present invention concentrates for wet brain electricity cap system schematic; To be that flexibility of the present invention is micro-ooze electrode structure schematic diagram to Fig. 2.
The implication of each Reference numeral is: 1: liquid capsule; 2: flexibility is micro-oozes electrode; 21: flexible hose 22: micro-ly ooze contact head; 23: conductive lead wire; 231: lead riser; 232: connecting line.
As shown in Figure 1, concentrate and comprise liquid capsule 1 for wet brain electricity cap and flexibility is micro-oozes electrode 2 two parts.
As shown in Figure 2, flexible micro-electrode 2 that oozes includes flexible hose 21, micro-ly oozes contact head 22, conductive lead wire 23.Wherein conductive lead wire 23 includes again lead riser 231 and connecting line 232 two.
Flexible micro-electrode 2 that oozes is prepared by following steps: step 1: the PDMS host of liquid state mixed with 10:1 ratio with sclerosing agent, inject the mould of flexible hose, the mode of evacuation is utilized to make the bubble floating in mixed liquor to surface and break, about one hour is baked at the baking box putting into 120 degree, make its curing molding, form flexible hose 21.Flexible hose 21 comprises front-end and back-end, and front-end and back-end can be the same, also can be different, and preferably, the front end of flexible hose 21 is wider than rear end, overall in ampuliform.Step 2: utilize high pressure that PEDOT material is made into electrostatic spinning structure, makes it form spongiform structure, inner forms cellular gap structure, is formed micro-ly to ooze contact head 22.Step 3: the lead riser 231 laying silver/silver chloride material composition at the inwall of flexible hose 21 one end, lead riser 231 is connected with connecting line 232, and connecting line 232 wears out flexible hose inwall, causes outside, is convenient to be connected with extraneous collecting device.Step 4: utilize the mode that is heating and curing flexible hose 21 and micro-contact head 22 that oozes to be combined, makes lead riser 231 and micro-to ooze contact head 22 as far as possible close, forms a closed Unified Global.Step 5: flexible hose 21 other end that liquid capsule 1 one end formed epoxy resin and PDMS are formed carries out heat cure, and formation is tightly connected.
Concentrating for wet brain electricity cap is then according to international 10-20 electroencephalogram lead system, will mention the electrode of making, be placed in the correspondence position of silk fabrics brain electricity cap one by one, and fix in above step, is formed and concentrates for wet brain electricity cap.
Liquid capsule 1 is the container storing the conductive liquid making the moistening of brain electricity cap top electrode, by with flexible hose 21 and each Electrode connection, liquid capsule 1 can be placed in the position on the brain electricity cap crown, provides moistening electrolyte by gravitional force to individual electrode; Also other positions can be placed in, by the power drive such as compressed air or Micropump conductive liquid to electrode movement.
In use, micro-ly ooze contact head 22 and head contact, conductive liquid enters through flexible hose 21, moistening is micro-ooze contact head and contact with it send out skin.The flexible hose of the timely forward end of liquid capsule energy supplements conductive liquid, maintains the moistening of skin electrode interface, is convenient to long term monitoring.And flexible hose front end micro-oozes each collection path short circuit that contact head can effectively avoid conductive liquid rapid osmotic to cause or the conductive liquid problem such as residual in a large number.The micro-electrode structure that oozes of flexibility simultaneously, because of its elastic characteristic, can increase the comfort level of real user, effectively prevent the senses of discomfort such as pain adjoint in the use of current electrode.
Above-described specific embodiment; object of the present invention, technical scheme and beneficial effect are further described; be understood that; the foregoing is only specific embodiments of the invention; be not limited to the present invention; within the spirit and principles in the present invention all, any amendment made, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (9)

1. a flexibility is micro-oozes electrode, it comprises flexible hose (21), micro-ly oozes contact head (22) and conductive lead wire (23), flexible hose (21) comprises front-end and back-end, front end is connected with micro-contact head (22) that oozes, rear end is connected with the liquid capsule (1) storing conductive liquid, flexible hose is full of conducting liquid in (21), and conductive lead wire (23) is immersed in this conducting solution.
2. flexibility according to claim 1 is micro-oozes electrode, it is characterized in that, flexible hose (21) is prepared from by polymer.
3. flexibility according to claim 2 is micro-oozes electrode, it is characterized in that, micro-contact head (22) that oozes is prepared from by flexible hole gap material, micro-ly ooze contact head (22) and head contact, conductive liquid enters through flexible hose (21), the micro-skin oozing contact head (22) and contact with it of moistening.
4. flexibility according to claim 3 is micro-oozes electrode, it is characterized in that, conductive lead wire (23) is made up of the lead riser (231) be in flexible hose (21) and connecting line (232) two parts be positioned at outside flexible pipe, wherein lead riser (231) is prepared by electrochemical electrode material, lead riser (231) is immersed in flexible pipe, be close to or neighbour micro-ooze contact head (22) place, connecting line (232) is worn out hose wall and is guided to outside flexible pipe, be connected with brain wave acquisition equipment, part through flexible hose (21) forms good sealing, the electrical connection of stablizing low-resistance is formed between two parts inside and outside pipe.
5. concentrate for wet brain electricity cap for one kind, it comprises liquid capsule (1) and flexibility is micro-oozes electrode (2), liquid capsule (1) is arranged on brain electricity cap, store to make flexible micro-container oozing the conductive liquid of electrode (2) moistening on brain electricity cap, flexible micro-electrode that oozes comprises flexible hose (21), micro-ly ooze contact head (22) and conductive lead wire (23), flexible hose (21) comprises front-end and back-end, front end is connected with micro-contact head (22) that oozes, rear end is connected with the liquid capsule (1) storing conductive liquid, flexible hose is full of conducting liquid in (21), conductive lead wire (23) is immersed in this conducting solution.
6. the brain electricity cap that concentrated confession according to claim 5 is wet, it is characterized in that, flexible hose (21) is prepared from by polymer.
7. the brain electricity cap that concentrated confession according to claim 6 is wet, it is characterized in that, micro-contact head (22) that oozes is prepared from by flexible hole gap material, micro-ly ooze contact head (22) and head contact, conductive liquid enters through flexible hose (21), the micro-skin oozing contact head (22) and contact with it of moistening.
8. the brain electricity cap that concentrated confession according to claim 7 is wet, it is characterized in that, conductive lead wire (23) is made up of the lead riser (231) be in flexible hose (21) and connecting line (232) two parts be positioned at outside flexible pipe, wherein lead riser (231) is prepared by electrochemical electrode material, lead riser (231) is immersed in flexible pipe, be close to or neighbour micro-ooze contact head (22) place, connecting line (232) is worn out hose wall and is guided to outside flexible pipe, be connected with brain wave acquisition equipment, part through flexible hose (21) forms good sealing, the electrical connection of stablizing low-resistance is formed between two parts inside and outside pipe.
9. brain electricity cap according to claim 5, it is characterized in that, liquid capsule (1) is placed in the position on the brain electricity cap crown, moistening electrolyte is provided to each electrode by gravitional force, or be placed in other positions, by the power drive such as compressed air or Micropump conductive liquid to electrode movement.
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Cited By (7)

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CN108742604A (en) * 2018-06-19 2018-11-06 苏州修普诺斯医疗器械有限公司 Wear-type brain wave acquisition terminal and brain wave acquisition method
CN109077724A (en) * 2018-07-26 2018-12-25 北京机械设备研究所 A kind of brain wave acquisition conducting medium transportation system and method
CN110072450A (en) * 2018-02-28 2019-07-30 北京布润科技有限责任公司 A kind of bioelectricity acquisition electrode and brain wave acquisition cap
CN111281381A (en) * 2020-03-13 2020-06-16 江苏集萃脑机融合智能技术研究所有限公司 Electrode and equipment for keeping long-term wetting of contact part
WO2020147556A1 (en) * 2019-01-15 2020-07-23 浙江强脑科技有限公司 Hydrogel reservoir electroencephalogram electrode
CN112043266A (en) * 2020-09-29 2020-12-08 江苏集萃脑机融合智能技术研究所有限公司 Comb-shaped electroencephalogram dry electrode wearing device
CN113349804A (en) * 2021-06-28 2021-09-07 上海大学 Flexible extensible quick automatic conductive paste injection device

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CN110072450A (en) * 2018-02-28 2019-07-30 北京布润科技有限责任公司 A kind of bioelectricity acquisition electrode and brain wave acquisition cap
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CN108742604A (en) * 2018-06-19 2018-11-06 苏州修普诺斯医疗器械有限公司 Wear-type brain wave acquisition terminal and brain wave acquisition method
CN109077724A (en) * 2018-07-26 2018-12-25 北京机械设备研究所 A kind of brain wave acquisition conducting medium transportation system and method
CN109077724B (en) * 2018-07-26 2021-12-07 北京机械设备研究所 Conductive medium conveying system and method for electroencephalogram acquisition
WO2020147556A1 (en) * 2019-01-15 2020-07-23 浙江强脑科技有限公司 Hydrogel reservoir electroencephalogram electrode
CN111281381A (en) * 2020-03-13 2020-06-16 江苏集萃脑机融合智能技术研究所有限公司 Electrode and equipment for keeping long-term wetting of contact part
CN112043266A (en) * 2020-09-29 2020-12-08 江苏集萃脑机融合智能技术研究所有限公司 Comb-shaped electroencephalogram dry electrode wearing device
CN113349804A (en) * 2021-06-28 2021-09-07 上海大学 Flexible extensible quick automatic conductive paste injection device

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