CN105395640A - Traditional Chinese medicine preparation for preventing and treating stroke - Google Patents

Traditional Chinese medicine preparation for preventing and treating stroke Download PDF

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Publication number
CN105395640A
CN105395640A CN201511006762.3A CN201511006762A CN105395640A CN 105395640 A CN105395640 A CN 105395640A CN 201511006762 A CN201511006762 A CN 201511006762A CN 105395640 A CN105395640 A CN 105395640A
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parts
chinese medicine
medicine preparation
traditional chinese
preventing
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Qingdao Changanda Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a traditional Chinese medicine preparation for preventing and treating a stroke. The traditional Chinese medicine preparation is prepared from, by weight, 46-63 parts of quisqualis, 40-55 parts of herba desmodii styracifolii, 35-48 parts of pomegranate rind, 31-42 parts of semen armeniacae amarum, 25-34 parts of herb of fimbriate orostachys, 18-27 parts of thymifolious euphorbia herb, 13-20 parts of cortex meliae and 9-14 parts of flos carthami. The traditional Chinese medicine preparation for preventing and treating the stroke is scientific in formula, simple in preparation method, convenient to use and significant in effect.

Description

Anti-antapoplectic Chinese medicine preparation
Technical field
The present invention relates to a kind of anti-antapoplectic Chinese medicine preparation.
Background technology
Apoplexy, names of disease of tcm, have exogenous wind and endogenous wind point, exogenous wind, because of caused by being invaded by exogenous pathogen (ailment said due to cold or exposure), says apoplexy (also known as syndrome of decoction GUI ZHI (Ramulus cinnamomi)) in treatise on Febrile Diseases name; Endogenous wind belongs to diseases caused by internal damage, also known as apoplexy, and apoplexy etc.Modern times generally claim apoplexy, refer to the syndrome similar to wind disease of diseases caused by internal damage more, how because QI and blood is inverse disorderly, the resistance of brain BI-syndrome involved the blood vessels or blood oozing from the body openings or subcuta neous tissue be caused by the brain.With unexpected dusk servant, hemiplegia, numb limbs and tense tendons, stiffness of the tongue in silence, crooked mouth and tongue, hemianesthesia etc. are the brain god disease of main manifestations.And there is onset urgency, change soon, as the disease of the feature of ailment said due to cold or exposure benefaction number change.Because primary disease sickness rate is high, mortality rate is high, disability rate is high, relapse rate is high and complication is many, so medical circle is listed as one of three large diseases threatening human health its same coronary heart disease, cancer.The primary disease cause of disease is more, and from clinical, with endogenous cause of ill, occasioner is in the majority.The generation of apoplexy, is summed up not outer void, fire, wind, expectorant, gas, blood six end.1. feelings will is disgruntled: overaction of the five emotions, heart-fire cruelly very, can priming endogenous wind and send out apoplexy.Clinical is many with rage impairing the liver, and because of rage then extreme hyperactivity of the liver-yang in no time, gas fire is all floating, and forcing blood gushes, and its time must be sent out.Probably sad as troubled thoughts, the nervous inducement being primary disease.2. eating and drinking without temperance: surfeit delicious food pure wine, dysfunction of the spleen in transportation, accumulatively wet raise phlegm, stagnation of phlegm converting into heat, priming liver-wind, folder expectorant is disturbed, can cause a disease and send out, especially bring out the strongest with excessive drinking.3. overwork: " Plain Questions vital QI of the body connecting with natural QI opinion " is said: " yang-energy person, bothers, and opens ", namely refers to personal yang-energy, if disturbance too, then excitedly not hold back.Primary disease also can because managing excessively, and body and the spirit is lost and supported, so that cloudy blood secretly consumes, and empty positive wind-transformation disturbance is for suffering from.Moreover indulge in sensual pleasures wound essence, be also water lose under, hyperactivity of fire in upper, morbidity because of.4. climate change: primary disease all can occur throughout the year, but change relevant with seasonal climate.Entering the winter turns cold suddenly, and cold-evil invades, and can affect blood vessels and follow row.Say as " Plain Questions regulating menstruation opinion " " cold solely to stay, then blood clotting position, solidifying then arteries and veins is obstructed ... ".Secondly suddenly turn early spring when warming up, on the occasion of the main order of chilly wind wood of fainting, planted agent is in liver, and wind sun is dark dynamic, and primary disease also can be caused to occur.5. the blood stasis of blood is stagnant: the formation of blood stasis many because of stagnation of QI hematogenous blockage or deficiency of vital energy fortune blood unable, or to accumulate in upper because of rage blood, or stagnate because feeling cold spasm, or to hinder liquid hematozemia stagnant etc. because of the moon of heat, the pathogenesis of primary disease accumulate mainly with rage blood or blood stasis due to qi deficiency the most common.The traditional Chinese medical science thinks apoplexy often because body is first empty, and negative and positive lose balance, and QI and blood is disorderly inverse, and expectorant stasis blocking is stagnant, caused by limbs mistake is supported.The expectorant stasis of blood is the major pathogenetic factor of primary disease, the stagnant venation of expectorant stasis blocking and cause limbs can not voluntary movement, then suffering limb is skinny for a long time, apathetic.
Summary of the invention
Technical problem to be solved by this invention is: provide one to prepare simply, act on rapidly, prevent antapoplectic Chinese medicine preparation safely and effectively.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
One provided by the invention prevents antapoplectic Chinese medicine preparation, is made up of the raw material of Chinese medicine of following weight portion: Fructus Quisqualis 46-63 part, Herba Desmodii Styracifolii 40-55 part, Pericarpium Granati 35-48 part, Semen Armeniacae Amarum 31-42 part, Herba Orostachyos 25-34 part, Euphorbia hypericifolia as Nakai 18-27 part, Cortex Meliae 13-20 part, Flos Carthami 9-14 part.
Preferably, Chinese medicine provided by the invention is made up of the raw material of Chinese medicine of following weight portion: Fructus Quisqualis 63 parts, Herba Desmodii Styracifolii 55 parts, Pericarpium Granati 48 parts, Semen Armeniacae Amarum 42 parts, Herba Orostachyos 34 parts, Euphorbia hypericifolia as Nakai 27 parts, Cortex Meliae 20 parts, 14 parts, Flos Carthami.
Usage and dosage: above-mentioned raw materials, is simmered in water after boiling with high heat 30 minutes after 30 minutes with warm water soaking again, taking liquid 150 milliliters, then add water and two to decoct, filter after twice medicinal liquid mixing, take at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
Beneficial effect of the present invention:
Scientific formula of the present invention, preparation method is simple, easy to use, Be very effective.In addition, excellent results of the present invention also shows: 1, the present invention uses theory of Chinese medical science to analyze prescription composition, according to each physicochemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains the preparation method of reasonable, stable active component.2, this not only has blood circulation promoting and blood stasis dispelling, promotes the effect that congestion absorbs, can also expansion of cerebral vascular effectively, and increase cerebral blood flow, improve cerebral tissue blood supply oxygen supply, promote neurocyte functional rehabilitation, selected materials is all Chinese medicine material, without any side effects.3, medicine of the present invention develops in conjunction with latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment, and all medicines share, and has evident in efficacy, safe ready, cheap feature.
Detailed description of the invention
Embodiment 1
The one that the present embodiment provides prevents antapoplectic Chinese medicine preparation, is made up of the raw material of Chinese medicine of following weight portion: Fructus Quisqualis 63 parts, Herba Desmodii Styracifolii 55 parts, Pericarpium Granati 48 parts, Semen Armeniacae Amarum 42 parts, Herba Orostachyos 34 parts, Euphorbia hypericifolia as Nakai 27 parts, Cortex Meliae 20 parts, 14 parts, Flos Carthami.
Clinical practice: 1, data and method 1.1 physical data 2010-2015 years, screens 200 routine paralytics in 5 hospitals, the age 35-70 year, 48 years old mean age, wherein male 123 example, women 77 example; All patients are at the age, and the aspect such as the state of an illness, the course of disease is through statistical procedures, and no significant difference (P > 0.05), has comparability.1.2 diagnostic criteria primary symptoms: hemiplegia, god knows unconsciousness, and speech is not smoothgoing puckery or in silence, hemiparesthesia, crooked mouth and tongue.Secondary disease: headache, dizzy, the refreshing change of pupil, drinking-water is sent out and is choked, order not wink partially, ataxia.Acute onset, premorbid has inducement more, often has premonitory symptom.Age of onset is many more than 40 years old.Possessing more than 2 primary symptoms, or 1 primary symptom, 2 diseases, can make a definite diagnosis in conjunction with onset, inducement, premonitory symptom, age; Do not possess above-mentioned condition, also can make a definite diagnosis in conjunction with imaging examination result.The all patients of 1.3 Therapeutic Method are divided into experimental group and each 100 examples of matched group at random, and experimental group takes Chinese medicine of the present invention, and matched group takes cow-bezoar bolus for resurrection.Observe four courses for the treatment of of treatment altogether.1.4 curative effect determinate standards are cured: clinical symptoms and sign all disappear, and lab testing recovers normal substantially; Effective: symptomatology is eliminated or cardinal symptom is eliminated, and lab testing significantly improves; Effective: clinical symptoms is eliminated substantially, lab testing is improved; Invalid: clinical symptoms and sign is unchanged or comparatively treatment before increase the weight of.Total effective rate=(cure number of cases+effective number of cases+effectively number of cases) ∕ total inspection case load × 100%.The therapeutic outcome of 1.5 therapeutic outcomes, two groups of patients,
Experimental group cures 89 examples, effective 7 examples, effective 3 examples, invalid 1 example, total effective rate 99%.
Matched group cures 50 examples, effective 15 examples, effective 5 examples, invalid 30 examples, total effective rate 70%.
From result, experimental group therapeutic effect is obviously better than matched group.
model case:
Case 1: revive certain, man, 71 years old, suffers from apoplexy for many years, and the right body is numb, unable throughout the year, speaks and pronounces indistinctly.Use Drug therapy of the present invention, after treating 3 courses for the treatment of, articulation and clear of speaking, but word speed is comparatively slow, and numb hand and foot makes moderate progress.Two courses for the treatment of of continuous treatment, brothers are no longer numb, can independently be careful, articulation and clear of speaking, and word speed is normal, cure.Case 2: Wei, man, 51 years old, suffers from apoplexy for many years, dysphonia, facial hemiparalysis, right limb movable function obstacle.Through using Drug therapy of the present invention, treat 2 courses for the treatment of, numb limbs and tense tendons disappears substantially, 3 courses for the treatment of of continual cure, and numb limbs and tense tendons disappears completely, and mind is clear, articulation and clear of speaking, and word speed is normal, and mouth eye is no longer crooked, healing.

Claims (2)

1. an anti-antapoplectic Chinese medicine preparation, is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Fructus Quisqualis 46-63 part, Herba Desmodii Styracifolii 40-55 part, Pericarpium Granati 35-48 part, Semen Armeniacae Amarum 31-42 part, Herba Orostachyos 25-34 part, Euphorbia hypericifolia as Nakai 18-27 part, Cortex Meliae 13-20 part, Flos Carthami 9-14 part.
2. Chinese medicine preparation according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Fructus Quisqualis 63 parts, Herba Desmodii Styracifolii 55 parts, Pericarpium Granati 48 parts, Semen Armeniacae Amarum 42 parts, Herba Orostachyos 34 parts, Euphorbia hypericifolia as Nakai 27 parts, Cortex Meliae 20 parts, 14 parts, Flos Carthami.
CN201511006762.3A 2015-12-29 2015-12-29 Traditional Chinese medicine preparation for preventing and treating stroke Pending CN105395640A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101926892A (en) * 2010-08-01 2010-12-29 黄超权 Medicament for treating brain stroke

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101926892A (en) * 2010-08-01 2010-12-29 黄超权 Medicament for treating brain stroke

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Application publication date: 20160316