CN105327133A - Traditional Chinese medicine preparation for treating qi stagnation and blood stasis type tubal obstruction infertility - Google Patents
Traditional Chinese medicine preparation for treating qi stagnation and blood stasis type tubal obstruction infertility Download PDFInfo
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- CN105327133A CN105327133A CN201510835070.3A CN201510835070A CN105327133A CN 105327133 A CN105327133 A CN 105327133A CN 201510835070 A CN201510835070 A CN 201510835070A CN 105327133 A CN105327133 A CN 105327133A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating qi stagnation and blood stasis type tubal obstruction infertility, which belongs to the technical field of traditional Chinese medicine. Aiming at the etiology of the qi stagnation and blood stasis type tubal obstruction infertility, according to the theory of modern traditional Chinese medicine, the traditional Chinese medicines including purple senecio, smilax riparia, platycarya fruit, rhodiola dumulosa, miscanthus gall, celandine roots, polygonum viviparum, lupuline bugle, calanthe discolor lindl, stellaria media, betel pepper and ophiorrhiza japonica which have the effects of promoting blood circulation, dispersing blood stasis, romoting qi circulation and dredging collaterals are selected to be decocted with water, so as to form decoction, and through a clinical experiment, the total effective rate reaches 87.5%.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation for the treatment of qi stagnation and blood stasis type Infertility caused by fallopian tube obstruction.
Background technology
Salpingemphraxis is the key factor causing female acyesis.It is reported, Infertility caused by fallopian tube obstruction accounts for infertile patient more than 30%, how because inflammation causes the adhesion of fallopian tube tube chamber or the complete obturation by the traction of surrounding scar tissue, makes caused by ovum can not converge with sperm.In recent years, along with the rising of sexually transmitted disease (STD) sickness rate, and pelvic inflammation, the increasing of uteroventral operation number of times, the sickness rate of primary disease is on the rise.Western medical treatment primary disease is based on hydrotubation, but curative effect is unstable, and effect is imprecise, and operative treatment pregnancy rate is low, and In vitro fertilization-embryo transplantation fails to popularize by technical limitations.Chinese traditional treatment primary disease method is various, has obtained certain curative effect at present, and salpingemphraxis is many to be caused by inflammation, clinical manifestation based on " stasis of blood ", so treat the product of first-selected blood circulation promoting and blood stasis dispelling.Modern pharmacological research proves, blood-activating and stasis-removing can improve microcirculation and the histotrophic nutrition of pelvic cavity local, regulate anabolism, absorb inflammatory lesions, be conducive to loosening of fallopian tube adhesion, promote reparation and the regeneration of tube chamber mucous epithelium, improve the function that fallopian tube transports ovum and sperm, and fertilization environment can be improved, increase uterus to the endometrial receptivity of cytula, thus improve pregnancy rate.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of qi stagnation and blood stasis type Infertility caused by fallopian tube obstruction.Be attributable to " breaks ", " lower abdominal pain ", " loss of fecundity ", " leukorrhagia ", " menoxenia ", “ mass in the abdomen of the traditional Chinese medical science according to the clinical manifestation of Infertility caused by fallopian tube obstruction " etc. category; salpingemphraxis is obstructed; the thing that blood stasis, phlegm-damp etc. must be had tangible resistance is in the inner; cause collaterals of the uterus retardance obstructed, cannot become pregnant by consolidating semen.Chinese traditional treatment should blood circulation promoting and blood stasis dispelling, promoting of the circulation of QI and removing the obstruction in the collaterals.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment qi stagnation and blood stasis type Infertility caused by fallopian tube obstruction is made up of the Chinese medicine of following weight portion: Herba Senecionis nudicaulis 12-18 part, Radix et Rhizoma Smilacis Ripariae 12-20 part, Fructus Platycaryae strobilaceac 15-25 part, Radix Rhodiolae Dumulosae 10-16 part, Caulis Miscanthis floriduli 20-30 part, Radix Chelidonii 5-11 part, Rhizoma Polygoni suffulti 12-16 part, Herba Ajugae Lupulinae 12-18 part, Herba seu Radix Calanthes 12-18 part, Herba malachii aquatici 10-18 Fen, Spica piperis betlis 3-7 part, Herba ophiorrhizae japonicae 20-30 part.
Preferred: Herba Senecionis nudicaulis 15 parts, Radix et Rhizoma Smilacis Ripariae 16 parts, Fructus Platycaryae strobilaceac 20 parts, Radix Rhodiolae Dumulosae 13 parts, Caulis Miscanthis floriduli 25 parts, Radix Chelidonii 8 parts, Rhizoma Polygoni suffulti 14 parts, Herba Ajugae Lupulinae 15 parts, Herba seu Radix Calanthes 15 parts, Herba malachii aquatici 14 parts, 5 parts, medicine beans, Herba ophiorrhizae japonicae 25 parts.
Preparation method: traditionally make decoction.
Herba Senecionis nudicaulis promoting blood circulation by removing blood stasis, regulating menstruation; Radix et Rhizoma Smilacis Ripariae inrigorating qi and promoting blood circulation, channels sootheing and network vessel quickening, anti-inflammatory analgesic; Fructus Platycaryae strobilaceac regulating qi and dispelling wind, reducing swelling and alleviating pain, removing dampness and killing parasites; Radix Rhodiolae Dumulosae the kidney invigorating, tranquilizing by nourishing the heart, regulating menstruation and activating blood; Caulis Miscanthis floriduli is pleasant to be delivered, except the stasis of blood; The detumescence of Radix Chelidonii removing blood stasis with potent drugs, hemostasis and pain-relieving; Rhizoma Polygoni suffulti falls apart, and blood stops blooding, circulation of qi promoting regulating menstruation; Herba Ajugae Lupulinae heat-clearing and toxic substances removing, promoting blood circulation and detumescence; Herba seu Radix Calanthes powder detoxifcation, relaxing muscles and tendons to promote blood circulation; Herba malachii aquatici heat-clearing and toxic substances removing, promoting blood circulation and detumescence; Spica piperis betlis warming the middle warmer and descending qi, eliminating stagnation expectorant; Herba ophiorrhizae japonicae promoting blood circulation to remove blood stasis.
Clinical data
1, physical data: all cases is all routine from I Out-patient Department patient 80 in June ,-2013 in January, 2011, is divided into treatment group and matched group at random, treatment group 40 example, 22 ~ 45 years old age, primary infertility 18 example, secondary infertility 22 example, one-sided salpingemphraxis 21 example, bilateral salpingo blocks 19 examples.Matched group 40 example, 20 ~ 42 years old age, primary infertility 18 example, secondary infertility 22 example, one-sided salpingemphraxis 20 example, bilateral salpingo blocks 20 examples, two groups of patient's physical data there was no significant differences (P > 0.05), have comparability.
2, Western medicine diagnose standard is with reference to " infertility therapy of combining Chinese and Western medicine " and the 7th edition " obstetrics and gynecology " teaching material of People's Health Publisher's publication; Tcm diagnosis standard drafts salpingitic infecundity qi stagnation and blood stasis type standard with reference to " new Chinese medicine guideline of clinical investigations " and " clinical disease diagnosis is according to curing improvement standard (the 2nd edition) ".
3, inclusive criteria meets Western medicine diagnose standard and tcm syndrome syndrome differential diagnosis standard person; 21 ~ 35 years old age; Menstrual cycle is 28 ~ 30d person; Signature Informed Consent Form person.
4, exclusion standard interstitial tubal, isthmus, ampulla obstructor; Other reasons such as congenital physiological defect or deformity, immunity, heredity, endocrine cause infertile person; Be associated with on inspection and confirm endometriosis, adenomyosis, hysteromyoma person; Turn out to be cervical lesions on inspection or have genital tuberculosis person; Bridegroom's or husband's side reproductive function exception person; Be associated with severe primary disease and the psychiatric patients such as cardiovascular, liver, kidney and hemopoietic system.
5, Therapeutic Method treatment group takes Chinese medicine preparation of the present invention, take Herba Senecionis nudicaulis 15g, Radix et Rhizoma Smilacis Ripariae 16g, Fructus Platycaryae strobilaceac 20g, Radix Rhodiolae Dumulosae 13g, Caulis Miscanthis floriduli 25g, Radix Chelidonii 8g, Rhizoma Polygoni suffulti 14g, Herba Ajugae Lupulinae 15g, Herba seu Radix Calanthes 15g, Herba malachii aquatici 14g, medicine beans 5g, Herba ophiorrhizae japonicae 25g, decocting becomes decoction, take medicine after clean period, every day 1 dose, menstrual period stop using, and within 1 month, are a course for the treatment of, treat three courses for the treatment of continuously; Matched group: western medical treatment routinely.
6, criterion of therapeutical effect combines originally study and define with reference to " new Chinese medicine guideline of clinical investigations ": 1. cure: treat the person of becoming pregnant after 3 courses for the treatment of; 2. effective: after treating 3 courses for the treatment of, though the one-sided unobstructed person of fallopian tube of not becoming pregnant; 3. invalid: through treating continuously, do not become pregnant and all obstructed person of bilateral.
7, after therapeutic outcome two groups treats 3 courses for the treatment of, comparitive study sees the following form.
| Group | n | Cure | Effectively | Invalid | Total effective rate |
| Treatment group | 40 | 25 | 10 | 5 | 87.5％ |
| Matched group | 40 | 18 | 8 | 14 | 65.0％ |
Detailed description of the invention
Embodiment one: take Herba Senecionis nudicaulis 12g, Radix et Rhizoma Smilacis Ripariae 12g, Fructus Platycaryae strobilaceac 15g, Radix Rhodiolae Dumulosae 10g, Caulis Miscanthis floriduli 20g, Radix Chelidonii 5g, Rhizoma Polygoni suffulti 12g, Herba Ajugae Lupulinae 12g, Herba seu Radix Calanthes 12g, Herba malachii aquatici 10g, medicine beans 3g, Herba ophiorrhizae japonicae 20g, traditionally make decoction.
Embodiment two: take Herba Senecionis nudicaulis 15g, Radix et Rhizoma Smilacis Ripariae 16g, Fructus Platycaryae strobilaceac 20g, Radix Rhodiolae Dumulosae 13g, Caulis Miscanthis floriduli 25g, Radix Chelidonii 8g, Rhizoma Polygoni suffulti 14g, Herba Ajugae Lupulinae 15g, Herba seu Radix Calanthes 15g, Herba malachii aquatici 14g, medicine beans 5g, Herba ophiorrhizae japonicae 25g, traditionally make decoction
Embodiment three: take Herba Senecionis nudicaulis 18g, Radix et Rhizoma Smilacis Ripariae 20g, Fructus Platycaryae strobilaceac 25g, Radix Rhodiolae Dumulosae 16g, Caulis Miscanthis floriduli 30g, Radix Chelidonii 11g, Rhizoma Polygoni suffulti 16g, Herba Ajugae Lupulinae 18g, Herba seu Radix Calanthes 18g, Herba malachii aquatici 18g, medicine beans 7g, Herba ophiorrhizae japonicae 30g, traditionally make decoction.
Claims (2)
1. treat a Chinese medicine preparation for qi stagnation and blood stasis type Infertility caused by fallopian tube obstruction, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Senecionis nudicaulis 12-18 part, Radix et Rhizoma Smilacis Ripariae 12-20 part, Fructus Platycaryae strobilaceac 15-25 part, Radix Rhodiolae Dumulosae 10-16 part, Caulis Miscanthis floriduli 20-30 part, Radix Chelidonii 5-11 part, Rhizoma Polygoni suffulti 12-16 part, Herba Ajugae Lupulinae 12-18 part, Herba seu Radix Calanthes 12-18 part, Herba malachii aquatici 10-18 part, Spica piperis betlis 3-7 part, Herba ophiorrhizae japonicae 20-30 part.
2. a kind of Chinese medicine preparation for the treatment of qi stagnation and blood stasis type Infertility caused by fallopian tube obstruction as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Senecionis nudicaulis 15 parts, Radix et Rhizoma Smilacis Ripariae 16 parts, Fructus Platycaryae strobilaceac 20 parts, Radix Rhodiolae Dumulosae 13 parts, Caulis Miscanthis floriduli 25 parts, Radix Chelidonii 8 parts, Rhizoma Polygoni suffulti 14 parts, Herba Ajugae Lupulinae 15 parts, Herba seu Radix Calanthes 15 parts, Herba malachii aquatici 14 Fen, Spica piperis betlis 5 parts, Herba ophiorrhizae japonicae 25 parts.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877474A (en) * | 2014-03-26 | 2014-06-25 | 李承功 | Traditional Chinese medicine composition for treating salpinx obstructive infertility caused by qi-stagnation and blood stasis |
| CN103893336A (en) * | 2014-03-26 | 2014-07-02 | 孙忠云 | Traditional Chinese medicine enema for treating salpinx obstructive infertility caused by qi stagnation and blood stasis and nursing method using same |
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- 2015-11-19 CN CN201510835070.3A patent/CN105327133A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877474A (en) * | 2014-03-26 | 2014-06-25 | 李承功 | Traditional Chinese medicine composition for treating salpinx obstructive infertility caused by qi-stagnation and blood stasis |
| CN103893336A (en) * | 2014-03-26 | 2014-07-02 | 孙忠云 | Traditional Chinese medicine enema for treating salpinx obstructive infertility caused by qi stagnation and blood stasis and nursing method using same |
Non-Patent Citations (3)
| Title |
|---|
| 叶根英: "插管通液加中药口服治疗输卵管性不孕症", 《浙江中西医结合杂志》 * |
| 殷岫绮: "宫腔镜下输卵管通液结合中药通管汤治疗输卵管性不孕症临床疗效分析", 《生殖与避孕》 * |
| 许瑞青等: "化瘀通络种子汤治疗输卵管阻塞性不孕症的临床观察", 《吉林中医药》 * |
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Application publication date: 20160217 |