CN105310894A - Microcapsule type anti-wrinkle eye cream - Google Patents

Microcapsule type anti-wrinkle eye cream Download PDF

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Publication number
CN105310894A
CN105310894A CN201510721801.1A CN201510721801A CN105310894A CN 105310894 A CN105310894 A CN 105310894A CN 201510721801 A CN201510721801 A CN 201510721801A CN 105310894 A CN105310894 A CN 105310894A
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parts
microcapsule
eye cream
porous starch
ethanol extract
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CN201510721801.1A
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Chinese (zh)
Inventor
袁彦洁
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CHONGQING XIAOWAN TRADE Co Ltd
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CHONGQING XIAOWAN TRADE Co Ltd
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Priority to CN201510721801.1A priority Critical patent/CN105310894A/en
Publication of CN105310894A publication Critical patent/CN105310894A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a microcapsule type anti-wrinkle eye cream, which is a microcapsule of a core-shell structure. A capsule wall material consists of sodium alginate, carboxymethyl cellulose sodium and hyaluronic acid; and a capsule core material consists of mink oil, squalene, lecithin, jojoba wax, glycerol, serine, corn porous starch, a pomegranate seed alcohol extract, a lucid ganoderma alcohol extract, a chamomile alcohol extract, coenzyme Q10 and a surfactant. By adsorbing grease ingredients and active ingredients in the capsule core material by virtue of the corn porous starch, the microcapsule type anti-wrinkle eye cream disclosed by the invention, when used, can promote the slow and uniform release of the active ingredients and the grease adsorbed in the corn porous starch and can avoid excessive nutrients and grease on skin due to massive release within a short time, so as to avoid the generation of fat granules; and the eye cream disclosed by the invention also has the characteristic of being good in permeability.

Description

A kind of anti-wrinkle eye cream of microcapsule-type
Technical field
The invention belongs to microcapsule technology field, be specifically related to a kind of anti-wrinkle eye cream of microcapsule-type.
Background technology
Eye skin is the thinnest skin of human body, is again activity position the most frequently simultaneously, but also is pull the maximum place of skin number of times in making up, and is very easy to grow wrinkle.The FAQs of eye has following several: black eye, eye pouch, edema, microgroove, dry stricture of vagina, crows-feet, fat granule, eyes lack expression etc., and these eye problems, once occur, are easy to make people seem aged without god.Eye cream is one of skin type product, and it can moisten eye part skin, alleviates the generation of wrinkle, microgroove, effectively prevents the generation of black eye, eye pouch problem, totally plays the effect alleviating eye part skin aging.Based on above-mentioned effect of eye cream, the personage that more and more likes to be beautiful using eye cream as one of daily indispensable skin care item.
If but the eye cream used is improper, also can bring certain harmful effect to eye skin.As most higher containing lubricant component in existing eye cream, contained neutraceutical active ingredients discharges too fast and is not easily absorbed, these oils and fatss or nutritional labeling are deposited on eye part skin, be easy to the generation causing fat granule for a long time in the past, fat granule, once produce elimination in the very difficult short time, can not be despised on the impact that eye part skin causes; If but the eye cream using quality comparatively frivolous, the moist degree of eye cream can be made again to decline, do not reach good maintenance effect.Moreover; the active substance adopted in existing eye cream is most not through certain protection, and directly contacts with external environment, along with the prolongation of time; these active substances be easy to be oxidized by the external world, photodissociation and lose the activity that should possess, and then cause product failure.
Summary of the invention
For prior art above shortcomings, technical problem to be solved by this invention is: the anti-wrinkle eye cream how providing a kind of microcapsule-type, neutraceutical active ingredients in this product evenly can be discharged in use and is easy to absorb, have nourish effective, can not cause that fat granule produces, active substance is not easily by feature that external environment is destroyed.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme: a kind of anti-wrinkle eye cream of microcapsule-type, and be a kind of microcapsule of nucleocapsid structure, cyst material comprises sodium alginate, Carboxymethyl cellulose sodium and hyaluronic acid; Core materials comprises mink oil, squalane, lecithin, Jojoba wax, glycerol, serine, corn porous starch, Semen Granati ethanol extract, ganoderol extract, Flos Matricariae chamomillae ethanol extract, coenzyme Q10 and surfactant.
Compared to existing technology, the present invention has following beneficial effect:
1, the present invention adopts corn porous starch, lubricant component in core materials and active component are adsorbed, and then the anti-wrinkle eye cream making microcapsule-type of the present invention in use, can make to be adsorbed on active component in corn porous starch and oils and fats slowly evenly discharges, and can not discharge in a large number the short time and bring too much nutrition and oil content to skin, and then the generation of fat granule can not be caused.
2, in order to strengthen the anti-wrinkle eye cream permeability of microcapsule-type of the present invention, the present invention is special by a large amount of experimental studies, choose mink oil, squalane, Jojoba wax is as core materials, and the collaborative compatibility relationship that further study between three, final discovery is when using " 15 ~ 20 parts of mink oils, 8 ~ 12 parts of squalanes and 4 ~ 10 parts of Jojoba waxes " time, the moist degree of this product can either be ensured, again can not be too greasy, and what is more important is when three plays collaborative compatibility effect with this ratio, the permeability of this product can be strengthened, and then enable skin fully absorb nutritional labeling, import respond well.
3, the present invention adopts microcapsule technology, neutraceutical active ingredients embedding is got up, makes this product in use, can not the impact that in external environment, light, heat, oxygen etc. are too much be subject to, effectively ensure that the activity of active substance is not destroyed, the effect extending product keeps the phase.
4, the present invention adopts active skull cap components as nutrient, and is undertaken composite by this several natural materials, and make them farthest play collaborative compatibility effect, the anti-wrinkle eye cream of giving microcapsule-type of the present invention combines effect with crease-resistant, moisturizing, antioxidative.
5, cyst wall hydrogel material of the present invention brings certain water moisture feeling to this product, and hyaluronic interpolation further increases the performance of keeping humidity of product, make this product in use, it is easier that eye part skin is pushed open, only need massage gently with finger and get final product uniform application, use convenient, the overnutrition at this position will be made to cause fat granule because product is deposited in a certain position of eye part skin.
6, shape of product of the present invention is regular, cyst wall has uniform thickness, and has uniform intensity, can retain the perfect shape of microcapsule and not be destroyed, the problem that capsule-core is revealed can not be caused, can not be damaged during effectively ensureing product stock, transport, shelf life.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, in the present embodiment if no special instructions, raw materials used be commercially available.
Described Semen Granati ethanol extract, ganoderol extract, Flos Matricariae chamomillae ethanol extract are after the ethanol water of employing 75% carries out alcohol extraction to Semen Granati, Ganoderma and Flos Matricariae chamomillae respectively, successively the extract that obtains of decompression recycling ethanol, lyophilization.
In following embodiment, the anti-wrinkle eye cream of microcapsule-type is adopted and is prepared with the following method:
(1) take sodium alginate, Carboxymethyl cellulose sodium and hyaluronic acid, add deionized water heating for dissolving 5 ~ 10min at 70 ~ 80 DEG C, obtain capsule wall solution A; Wherein, the deionized water volume added is 30 ~ 40 times of sodium alginate, Carboxymethyl cellulose sodium and hyaluronic acid gross mass;
(2) mink oil, squalane, lecithin, Jojoba wax, glycerol, serine, corn porous starch, Semen Granati ethanol extract, ganoderol extract, Flos Matricariae chamomillae ethanol extract, coenzyme Q10 and surfactant is taken, mix homogeneously, under 70 ~ 80 DEG C of water bath condition, stir 0.5 ~ 1h, obtain capsule-core mixture B; The mixing speed of wherein said stirring is 120 ~ 160r/min;
(3) mixed by capsule wall solution A and capsule-core mixture B, after blender dispersion 20 ~ 30min, homogenizing 5 ~ 10min, obtains homogenizing fluid C; Wherein, the rotating speed of described blender is 300 ~ 350r/min, and the homogenization pressure of described homogenizing is 35 ~ 50MPa;
(4) homogenizing fluid C is heated to 70 ~ 80 DEG C, using glue head dropper homogenizing fluid C to be slowly added dropwise to mass concentration is in the calcium chloride solution of 5 ~ 7%;
(5) calcium chloride solution after step (4) instillation homogenizing fluid C is filtered, discard filtrate, collect oversize;
(6) the oversize deionized water wash collected step (5) 2 ~ 3 times, obtains the anti-wrinkle eye cream of described microcapsule-type.
Embodiment 1:
An anti-wrinkle eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 40 parts of sodium alginates, 10 parts of Carboxymethyl cellulose sodium and 6 parts of hyaluronic acids; Core materials is: 15 parts of mink oils, 8 parts of squalanes, 6 parts of lecithin, 4 parts of Jojoba waxes, 6 parts of glycerol, 3 parts of serines, 6 parts of corn porous starch, 2 parts of Semen Granati ethanol extract, 1 part of ganoderol extract, 2 parts of Flos Matricariae chamomillae ethanol extract, 1 part of coenzyme Q10 and 4 parts of span 20s.
Embodiment 2:
An anti-wrinkle eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 50 parts of sodium alginates, 15 parts of Carboxymethyl cellulose sodium and 8 parts of hyaluronic acids; Core materials is: 20 parts of mink oils, 12 parts of squalanes, 9 parts of lecithin, 10 parts of Jojoba waxes, 8 parts of glycerol, 6 parts of serines, 8 parts of corn porous starch, 3 parts of Semen Granati ethanol extract, 3 parts of ganoderol extracts, 3 parts of Flos Matricariae chamomillae ethanol extract, 2 parts of coenzyme Q10s and 7 parts of span 20s.
Embodiment 3:
An anti-wrinkle eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 42 parts of sodium alginates, 12 parts of Carboxymethyl cellulose sodium and 8 parts of hyaluronic acids; Core materials is: 18 parts of mink oils, 10 parts of squalanes, 8 parts of lecithin, 6 parts of Jojoba waxes, 8 parts of glycerol, 5 parts of serines, 6 parts of corn porous starch, 2 parts of Semen Granati ethanol extract, 1 part of ganoderol extract, 2 parts of Flos Matricariae chamomillae ethanol extract, 2 parts of coenzyme Q10s and 6 parts of span 20s.
The present invention adopts corn porous starch, lubricant component in core materials and active component are adsorbed, and then the anti-wrinkle eye cream making microcapsule-type of the present invention in use, can make to be adsorbed on active component in corn porous starch and oils and fats slowly evenly discharges, and can not discharge in a large number the short time and bring too much nutrition and oil content to skin, and then the generation of fat granule can not be caused.
In order to strengthen the anti-wrinkle eye cream permeability of microcapsule-type of the present invention, the present invention is special by a large amount of experimental studies, choose mink oil, squalane, Jojoba wax is as core materials, and the collaborative compatibility relationship that further study between three, final discovery is when using " 15 ~ 20 parts of mink oils, 8 ~ 12 parts of squalanes and 4 ~ 10 parts of Jojoba waxes " time, the moist degree of this product can either be ensured, again can not be too greasy, and what is more important is when three plays collaborative compatibility effect with this ratio, the permeability of this product can be strengthened, and then enable skin fully absorb nutritional labeling, import respond well.
What finally illustrate is, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although applicant's reference preferred embodiment is to invention has been detailed description, those of ordinary skill in the art is to be understood that, technical scheme of the present invention is modified or equivalent replacement, and do not depart from the aim of technical solution of the present invention and scope, all should be encompassed in the middle of right of the present invention.

Claims (4)

1. an anti-wrinkle eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, it is characterized in that, cyst material comprises sodium alginate, Carboxymethyl cellulose sodium and hyaluronic acid; Core materials comprises mink oil, squalane, lecithin, Jojoba wax, glycerol, serine, corn porous starch, Semen Granati ethanol extract, ganoderol extract, Flos Matricariae chamomillae ethanol extract, coenzyme Q10 and surfactant.
2. the anti-wrinkle eye cream of microcapsule-type according to claim 1, it is characterized in that, described surfactant is span 20.
3. the anti-wrinkle eye cream of microcapsule-type according to claim 2, it is characterized in that, the parts by weight of described cyst material are: 40 ~ 50 parts of sodium alginates, 10 ~ 15 parts of Carboxymethyl cellulose sodium and 6 ~ 8 parts of hyaluronic acids; The parts by weight of described core materials are: 15 ~ 20 parts of mink oils, 8 ~ 12 parts of squalanes, 6 ~ 9 parts of lecithin, 4 ~ 10 parts of Jojoba waxes, 6 ~ 8 parts of glycerol, 3 ~ 6 parts of serines, 6 ~ 8 parts of corn porous starch, 2 ~ 3 parts of Semen Granati ethanol extract, 1 ~ 3 part of ganoderol extract, 2 ~ 3 parts of Flos Matricariae chamomillae ethanol extract, 1 ~ 2 part of coenzyme Q10 and 4 ~ 7 parts of span 20s.
4. the anti-wrinkle eye cream of microcapsule-type according to claim 2, it is characterized in that, the parts by weight of described cyst material are: 42 parts of sodium alginates, 12 parts of Carboxymethyl cellulose sodium and 8 parts of hyaluronic acids; The parts by weight of described core materials are: 18 parts of mink oils, 10 parts of squalanes, 8 parts of lecithin, 6 parts of Jojoba waxes, 8 parts of glycerol, 5 parts of serines, 6 parts of corn porous starch, 2 parts of Semen Granati ethanol extract, 1 part of ganoderol extract, 2 parts of Flos Matricariae chamomillae ethanol extract, 2 parts of coenzyme Q10s and 6 parts of span 20s.
CN201510721801.1A 2015-10-30 2015-10-30 Microcapsule type anti-wrinkle eye cream Pending CN105310894A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106087540A (en) * 2016-06-12 2016-11-09 福建希源纸业有限公司 Starch spray drying prepares the method for capsule-type papermaking filler
CN107095814A (en) * 2017-05-03 2017-08-29 周晓浩 The crease-resistant nutrient solution of pomegranate seed
CN109288714A (en) * 2018-11-21 2019-02-01 广州若双化妆品有限公司 A kind of eye cream of blue ray radiation preventing and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391288B1 (en) * 1999-07-27 2002-05-21 Shiseido Co., Ltd. Microcapsule and method of making the same
CN103202469A (en) * 2013-03-28 2013-07-17 吉林大学 Egg yolk lecithin microcapsules and preparation method thereof
CN104398392A (en) * 2014-12-01 2015-03-11 重庆小丸科贸有限公司 Hydrogel microcapsule and application thereof in anti-ageing cosmetic

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391288B1 (en) * 1999-07-27 2002-05-21 Shiseido Co., Ltd. Microcapsule and method of making the same
CN103202469A (en) * 2013-03-28 2013-07-17 吉林大学 Egg yolk lecithin microcapsules and preparation method thereof
CN104398392A (en) * 2014-12-01 2015-03-11 重庆小丸科贸有限公司 Hydrogel microcapsule and application thereof in anti-ageing cosmetic

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吴克刚等: "《食品微胶囊技术》", 31 July 2006, 中国轻工业出版社 *
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106087540A (en) * 2016-06-12 2016-11-09 福建希源纸业有限公司 Starch spray drying prepares the method for capsule-type papermaking filler
CN107095814A (en) * 2017-05-03 2017-08-29 周晓浩 The crease-resistant nutrient solution of pomegranate seed
CN109288714A (en) * 2018-11-21 2019-02-01 广州若双化妆品有限公司 A kind of eye cream of blue ray radiation preventing and preparation method thereof

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Application publication date: 20160210