CN105310803A - Minimally invasive embedded shape memory interbody fusion cage - Google Patents
Minimally invasive embedded shape memory interbody fusion cage Download PDFInfo
- Publication number
- CN105310803A CN105310803A CN201410358699.9A CN201410358699A CN105310803A CN 105310803 A CN105310803 A CN 105310803A CN 201410358699 A CN201410358699 A CN 201410358699A CN 105310803 A CN105310803 A CN 105310803A
- Authority
- CN
- China
- Prior art keywords
- memory
- curb girder
- ridge purlin
- axle
- shape memory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention relates to a minimally invasive embedded shape memory interbody fusion cage used for spine surgery. The minimally invasive embedded shape memory interbody fusion cage is of a frame-type hollow structure and is composed of multiple stand column shafts, front beams, side beams, memory deformation side beams, memory deformation front beams, multiple shaft peripheral rings and an open window. The front beams, the side beams, the memory deformation side beams and the memory deformation front beams are connected with the shaft peripheral rings through clamping groove structures and raised head structures, and the shaft peripheral rings of different layers are arranged on the corresponding stand column shafts in a sleeving mode, wherein the memory deformation side beams and the memory deformation front beams are made of medical titanium-nickel memory alloy with a shape memory function. The minimally invasive embedded shape memory interbody fusion cage can enter an intervertebral space through an existing tiny channel and has the advantages of being small in wound, less in pain, rapid in recovery, few in complication and the like; after the minimally invasive embedded shape memory interbody fusion cage is spread, the contact area of the interbody fusion cage and an upper end plate and a lower end plate of a vertebral body can be increased, more sclerotin can be implanted, and the fusion rate is increased.
Description
Technical field
The present invention relates to a kind of Wicresoft for medical domain, spinal surgery and insert shape memory Invasive lumbar fusion device.
Background technology
The diseases such as the prolapse of cervical intervertebral disc that spinal column degeneration causes, stenosis, cervical vertebral segment shakiness, protrusion of thoracic intervertebral disk, prolapse of lumbar intervertebral disc, lumbar spinal stenosis, Lumbar segmental instability, lumbar spondyloiisthesis are very common clinically.Lumbar intervertebral fusion determined curative effect, existing century-old applicating history is the Main Means of this type of disease for the treatment of, is also one of modus operandi of being most widely used of spinal surgery.
Interbody fusion comprises anterior intervertebral fusion art, way of escape interbody fusion, transforaminal approach lumbar intervertebral fusion, lumbar vertebra side approach interbody fusion etc.
Anterior intervertebral fusion art enters intervertebral space from front, can more effectively strut and recover disc height, simultaneously anterior lateral cervical approach can remove the intervertebral disc of degeneration more up hill and dale, and ALIF need not tractive dural sac and nerve root, thus avoids the damage of nerve root and dural sac.In addition, ALIF also protects the complete of the lumbar vertebra such as vertebral plate, Minor articulus rear structure.The front road of cervical operation is common, but lumbar surgery anterior lateral cervical approach easy damaged trunk and sympathetic plexus, cause the complication such as retrograde ejaculation and urine obstacle
Way of escape interbody fusion completes intervertebral fusion through way of escape canalis spinalis, to obtain the stable of center pillar before lumbar vertebra, transforaminal approach lumbar intervertebral fusion enters interspace of lumbar vertebrae from one-sided transforaminal, complete a series of processes such as discectomy, bone grafting, Invasive lumbar fusion device implantation, before lumbar vertebra bilateral also can be provided, center pillar support, and additional rear outside bone grafting and strong internal fixtion, the surrounding that also can obtain lumbar vertebra merges.Lumbar vertebra side approach interbody fusion reaches lumbar vertebra side by side separating muscle, carries out the operation of merging of reducing pressure.
Various modus operandi is open surgery, and wound is comparatively large, and complication is more; Along with developing rapidly of the high-precision technology of medical operation device, digital imaging techniques and Computerized intelligent technology etc., the theory of minimally invasive surgery is constantly by surgeon recognition and acceptance, and the Minimally Invasive Surgery mode with multiple advantages such as wound is little, painful gently, recovery is fast, few intercurrent diseases is constantly explored by surgery.
As minimal incision * assists descending anterior intervertebral fusion art, side approach interbody fusion in conjunction with special scope drag hook or video image dendoscope, way of escape scope assists descending way of escape Spine interbody fusion, transforaminal lumbar interbody fusion.
External Grob etc. utilize two pieces of oblique screws to be greater than 25% disc height patient's row lumbar spinal fusion (Directpediculo-bodyfixation) of being less than 75% simultaneously to the reach of upper vertebral body, this technology is thought that non-slippage patient is also the indication of this operation by Birkenmaier etc., under navigation, carry out this operation simultaneously, called after: oblique lumbar intervertebral fusion (GuidedObliqueLumbarInterbodyFusion, GO-LIF) of navigating.
These invasive surgery formulas all have the multiple advantages such as wound is little, painful gently, recovery is fast, few intercurrent disease above.
But traditional Invasive lumbar fusion device because otch diminish, cannot be suitable for, need novel small-sized Invasive lumbar fusion device, if but Invasive lumbar fusion device volume too small can causing again diminish with the contact area of upper and lower soleplate, the intervertebral fusion that cannot realize ideal, causes operative failure.
Along with the improvement of Invasive lumbar fusion device, currently reported expansiveness Invasive lumbar fusion device (as: B-twin product, Disc-O-techMedicalTechnologies, Ltd.Israel), the mode of percutaneous can be adopted to implant, expand after implanting, reach the object of intervertebral fusion.But it adopts mechanical rotary compression mode, middle bone grafting area is little, only scatters in alabastrum shape.
Current memorial alloy technology can reach small implantation, the effect strutted in vivo, publication (publication number CN1449725A before, the patent No.: 03113393.2) describe a kind of Microwound vertebral body fusion device made of shape memory alloy strutted by round as a ball formula technology, this technology make use of the function of memory metal shape memory, but after strutting, goes out and contact outside upper and lower soleplate up and down, unobstructed fence around, sclerotin easily seepage towards periphery.But marmem is a large advantage material of minimally Invasive lumbar fusion device.
Summary of the invention
Insert Invasive lumbar fusion device under how reaching Wicresoft's passage, make it strut in vivo, can well bone-graft fusion be carried out simultaneously.We devise this Wicresoft and insert shape memory Invasive lumbar fusion device.
The present invention is achieved by the following technical solutions:
1, shape memory Invasive lumbar fusion device is inserted by this Wicresoft is frame-type hollow structure, and by some root post axles, ridge purlin, curb girder, curb girder is out of shape in memory, memory distortion ridge purlin, several axle chow rings and an open window form.
2, ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends are equipped with a kind of structure in notch or plush copper structure, periphery 360 degree of scopes of axle chow ring are also provided with a kind of structure in notch or plush copper structure, if notch is established at ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends, then periphery 360 degree of scopes of axle chow ring establish plush copper structure; If plush copper structure is established at ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends, then periphery 360 degree of scopes of axle chow ring establish notch, namely ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends are connected to each other by notch and plush copper structure and axle chow ring, make ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin can be in rotary moving around the periphery of axle chow ring.
3, ridge purlin two ends are all connected on an axle chow ring be connected with one end of curb girder.
4, one end of curb girder is connected on an axle chow ring be connected with one end of ridge purlin, and the other end is connected to one and is out of shape on axle chow ring that ridge purlin is connected with remembering with memory distortion curb girder.
5, memory distortion curb girder is connected on an axle chow ring be connected with one end of curb girder with the two ends of memory distortion ridge purlin
6, the axle chow ring of different aspects in correspondence with each other be enclosed within column axle, can rotate around column axle, constitute solid space structure of the present invention.
7, memory distortion curb girder and memory distortion ridge purlin are made by the medical titanium with shape memory function-nickel memorial alloy, its shape changes because temperature is different, thus after reaching implant into body, straighten at 37 degrees centigrade, make overall change large, the contact area of increase and the upper and lower soleplate of vertebral body, more implants sclerotin, improves fusion rate.
8, the face of the ridge purlin composition of some different aspects is provided with open window, and artificial bone or autologous bone can insert inside of the present invention by open window.
9, a part of ridge purlin in ridge purlin of the present invention and curb girder and curb girder are made up of the material of X-ray opaque line, can provide position judgment effect for operation.
The beneficial effect that the present invention can reach
This Wicresoft inserts the non-deforming precursor of shape memory Invasive lumbar fusion device and amasss small, intervertebral space can be entered by passage small at present, when entering after in body, when temperature reaches 37 degrees centigrade, memory distortion curb girder straightens with memory distortion ridge purlin, makes overall change greatly, thus achieves the goal, the present invention combines current diversified Wicresoft interbody fusion, can meet the requirement that its passage aisle is implanted.
Therefore, the present invention is in conjunction with less invasive techniques, and not only have the advantages such as wound is little, painful gently, recovery is fast, few intercurrent disease, it can increase the contact area of the upper and lower soleplate with vertebral body after strutting, more implant sclerotin, improves fusion rate.
Accompanying drawing explanation
Accompanying drawing: Fig. 1: the structural representation before the present invention is not out of shape.
Fig. 2: the structural representation after the present invention's distortion.
Fig. 3: the present invention is not out of shape front top view.
Fig. 4: the present invention is out of shape rear top view.
Fig. 5: the schematic cross-section of notch of the present invention or plush copper structure
In figure: 1. curb girder; 2. axle chow ring; 3. column axle; 4. memory distortion curb girder; 5. memory distortion ridge purlin; 6. ridge purlin; 7. open window; 8. plush copper structure; 9. notch.
Detailed description of the invention
Embodiment 1:
Anterior spinal fusion art, under Wicresoft's condition or under open condition, reach spinal column front, confirm disease vertebra, again intervertebral disc, worn sclerotin, fully reduces pressure.That gets suitable size is not out of shape the present invention one, inserts in intervertebral space, now, memory distortion curb girder 4 and memory distortion ridge purlin 5 slowly straighten in vivo, become apperance in Fig. 2, confirm under C arm X-ray machine position can after, by special supporting funnel, implantable artificial bone or autologous bone.
Embodiment 2:
Pedicle is through intervertebral disc oblique screw internal fixation associating Invasive lumbar fusion device implantation, under scope or under open traditional operation condition, by rear operative approach or by intervertebral spinal fusion operative approach, removal of disc, worn upper and lower soleplate, after decompression fully, that gets suitable size is not out of shape the present invention one, insert in intervertebral space, now, memory distortion curb girder 4 and memory distortion ridge purlin 5 slowly straighten in vivo, become apperance in Fig. 2, confirm under C arm X-ray machine position can after, by special supporting funnel, implantable artificial bone or autologous bone.
Embodiment 3
Via Posterior Spinal Approach decompression four nail two rod internal fixation associating Invasive lumbar fusion device implantation, under scope or under open traditional operation condition, by rear operative approach or by intervertebral spinal fusion operative approach, removal of disc, worn upper and lower soleplate, after decompression fully, that gets suitable size is not out of shape the present invention one, insert in intervertebral space, now, memory distortion curb girder 4 and memory distortion ridge purlin 5 slowly straighten in vivo, become apperance in Fig. 2, confirm under C arm X-ray machine position can after, by special supporting funnel, implantable artificial bone or autologous bone.
Embodiment 4: row spinal column side approach interbody fusion, under scope or under open traditional operation condition, by side waist muscle or spatium intermusculare approach, removal of disc, worn upper and lower soleplate, after decompression fully, that gets suitable size is not out of shape the present invention one, insert in intervertebral space, now, memory distortion curb girder 4 and memory distortion ridge purlin 5 slowly straighten in vivo, become apperance in Fig. 2, confirm under C arm X-ray machine position can after, by special supporting funnel, implantable artificial bone or autologous bone.
Claims (9)
1. a shape memory Invasive lumbar fusion device is inserted by Wicresoft, it is characterized in that: be frame-type hollow structure, and by some root post axles, ridge purlin, curb girder, curb girder is out of shape in memory, memory distortion ridge purlin, several axle chow rings and an open window form.
2. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends are equipped with a kind of structure in notch or plush copper structure, periphery 360 degree of scopes of axle chow ring are also provided with a kind of structure in notch or plush copper structure: if ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends establish notch, then periphery 360 degree of scopes of axle chow ring establish plush copper structure; If plush copper structure is established at ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends, then periphery 360 degree of scopes of axle chow ring establish notch, and namely ridge purlin, curb girder, memory distortion curb girder, memory distortion ridge purlin two ends are connected to each other by notch and plush copper structure and axle chow ring.
3. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: ridge purlin two ends are all connected on an axle chow ring be connected with one end of curb girder.
4. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: one end of curb girder is connected on an axle chow ring be connected with one end of ridge purlin, the other end is connected to one and is out of shape on axle chow ring that ridge purlin is connected with remembering with memory distortion curb girder.
5. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: memory distortion curb girder is connected on an axle chow ring be connected with one end of curb girder with the two ends of memory distortion ridge purlin.
6. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: the axle chow ring of different aspects in correspondence with each other be enclosed within column axle, can rotate around column axle, constitute solid space structure of the present invention.
7. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: memory distortion curb girder and memory distortion ridge purlin are made by the medical titanium with shape memory function-nickel memorial alloy.
8. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: the face of the ridge purlin composition of some different aspects is provided with open window.
9. shape memory Invasive lumbar fusion device is inserted by Wicresoft according to claim 1, it is characterized in that: a part of ridge purlin in ridge purlin and curb girder and curb girder are made up of the material of X-ray opaque line.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410358699.9A CN105310803B (en) | 2014-07-27 | 2014-07-27 | A kind of embedded with minimal invasion shape memory Invasive lumbar fusion device |
| CN201811176168.2A CN109157311B (en) | 2014-07-27 | 2014-07-27 | Minimally invasive implantation shape memory interbody fusion cage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410358699.9A CN105310803B (en) | 2014-07-27 | 2014-07-27 | A kind of embedded with minimal invasion shape memory Invasive lumbar fusion device |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811176168.2A Division CN109157311B (en) | 2014-07-27 | 2014-07-27 | Minimally invasive implantation shape memory interbody fusion cage |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105310803A true CN105310803A (en) | 2016-02-10 |
| CN105310803B CN105310803B (en) | 2018-11-23 |
Family
ID=55239787
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811176168.2A Active CN109157311B (en) | 2014-07-27 | 2014-07-27 | Minimally invasive implantation shape memory interbody fusion cage |
| CN201410358699.9A Active CN105310803B (en) | 2014-07-27 | 2014-07-27 | A kind of embedded with minimal invasion shape memory Invasive lumbar fusion device |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811176168.2A Active CN109157311B (en) | 2014-07-27 | 2014-07-27 | Minimally invasive implantation shape memory interbody fusion cage |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN109157311B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106510906A (en) * | 2017-01-01 | 2017-03-22 | 常州华森医疗器械有限公司 | Supporting structure portion of porous titanium interbody fusion cage |
| CN106667626A (en) * | 2017-01-01 | 2017-05-17 | 常州华森医疗器械有限公司 | Porous titanium interbody fusion cage and method for preparing same |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112674916B (en) * | 2020-12-17 | 2022-12-27 | 湖南华翔医疗科技有限公司 | Intervertebral fusion cage |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017207A1 (en) * | 1996-10-21 | 1998-04-30 | Synthes Ag Chur | Surgical prosthetic device |
| CN1449725A (en) * | 2003-05-01 | 2003-10-22 | 东南大学 | Microwound vertebral body fusion device made of shape memory alloy |
| CN2910134Y (en) * | 2005-11-24 | 2007-06-13 | 袁文 | Self-opening Ni-Ti memory alloy interspinous fusion device for cervical vertebrae |
| US20090062916A1 (en) * | 2007-08-27 | 2009-03-05 | Biomedical Enterprises, Inc. | Method and apparatus for an osteotomy fixation or arthrodesis cage |
| CN201551419U (en) * | 2009-11-19 | 2010-08-18 | 甘肃国脉生物科技有限责任公司 | Memory alloy vertebral body bracket |
| CN201558198U (en) * | 2009-11-24 | 2010-08-25 | 孙正义 | Memory alloy anterior lumbar interbody fusion device |
| CN101999951A (en) * | 2010-12-04 | 2011-04-06 | 兰州西脉记忆合金股份有限公司 | Memory alloy artificial cervical intervertebral disc |
| CN102462562A (en) * | 2010-10-28 | 2012-05-23 | 朴庆佑 | Intervertebral cage having flexibility |
| KR101371418B1 (en) * | 2013-03-06 | 2014-03-25 | (주)강앤박메디컬 | Intervertebral fusion device |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5701200A (en) * | 1999-07-02 | 2001-01-22 | Petrus Besselink | Reinforced expandable cage |
| US6991653B2 (en) * | 2002-03-21 | 2006-01-31 | Sdgi Holdings, Inc. | Vertebral body and disc space replacement devices |
| US20040010315A1 (en) * | 2002-03-29 | 2004-01-15 | Song John K. | Self-expanding intervertebral device |
| CN2579357Y (en) * | 2002-11-29 | 2003-10-15 | 王建华 | Lumber vertebrae anastomat |
| US7344564B2 (en) * | 2004-06-08 | 2008-03-18 | Spinal Generations, Llc | Expandable spinal stabilization device |
| US20070233255A1 (en) * | 2006-03-06 | 2007-10-04 | Vermillion Technologies, Llc | Intervertebral disc replacement prosthesis |
| EP2624790B1 (en) * | 2010-10-05 | 2020-02-26 | EIT Emerging Implant Technologies GmbH | Intervertebral device |
| WO2012135764A1 (en) * | 2011-03-30 | 2012-10-04 | Trinity Ortopedics, Llc | Articulating interbody cage and methods thereof |
| EP2606860B1 (en) * | 2011-12-22 | 2016-07-20 | Biedermann Technologies GmbH & Co. KG | Expandable intervertebral implant |
-
2014
- 2014-07-27 CN CN201811176168.2A patent/CN109157311B/en active Active
- 2014-07-27 CN CN201410358699.9A patent/CN105310803B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998017207A1 (en) * | 1996-10-21 | 1998-04-30 | Synthes Ag Chur | Surgical prosthetic device |
| CN1449725A (en) * | 2003-05-01 | 2003-10-22 | 东南大学 | Microwound vertebral body fusion device made of shape memory alloy |
| CN2910134Y (en) * | 2005-11-24 | 2007-06-13 | 袁文 | Self-opening Ni-Ti memory alloy interspinous fusion device for cervical vertebrae |
| US20090062916A1 (en) * | 2007-08-27 | 2009-03-05 | Biomedical Enterprises, Inc. | Method and apparatus for an osteotomy fixation or arthrodesis cage |
| CN201551419U (en) * | 2009-11-19 | 2010-08-18 | 甘肃国脉生物科技有限责任公司 | Memory alloy vertebral body bracket |
| CN201558198U (en) * | 2009-11-24 | 2010-08-25 | 孙正义 | Memory alloy anterior lumbar interbody fusion device |
| CN102462562A (en) * | 2010-10-28 | 2012-05-23 | 朴庆佑 | Intervertebral cage having flexibility |
| CN101999951A (en) * | 2010-12-04 | 2011-04-06 | 兰州西脉记忆合金股份有限公司 | Memory alloy artificial cervical intervertebral disc |
| KR101371418B1 (en) * | 2013-03-06 | 2014-03-25 | (주)강앤박메디컬 | Intervertebral fusion device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106510906A (en) * | 2017-01-01 | 2017-03-22 | 常州华森医疗器械有限公司 | Supporting structure portion of porous titanium interbody fusion cage |
| CN106667626A (en) * | 2017-01-01 | 2017-05-17 | 常州华森医疗器械有限公司 | Porous titanium interbody fusion cage and method for preparing same |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105310803B (en) | 2018-11-23 |
| CN109157311A (en) | 2019-01-08 |
| CN109157311B (en) | 2020-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11771564B2 (en) | Articulating and expandable vertebral implant | |
| US20230255788A1 (en) | Articulating expandable intervertebral implant | |
| US11896493B2 (en) | Expandable intervertebral spacer | |
| CN109758272B (en) | Distracting fusion cage with adjustable middle bone grafting height | |
| US20170266016A1 (en) | Stabilized intervertebral spacer | |
| CN105796215B (en) | Lumbar intervertebral fusion device can be strutted | |
| CN105310803A (en) | Minimally invasive embedded shape memory interbody fusion cage | |
| CN101999951B (en) | Memory alloy artificial cervical intervertebral disc | |
| CN103610521A (en) | Interbody fusion cage | |
| CN106073876B (en) | Fusion device | |
| CN212234810U (en) | Distractable intervertebral fusion cage | |
| CN104644254B (en) | A kind of fracture-dislocation of cervical spine front road reduction fixation system | |
| CN201912273U (en) | Artificial intervertebral disc of cervical vertebra made from memory alloy | |
| CN205586120U (en) | A interior plant, intervertebral bone grafting integration ware and artifical intervertebral disc for vertebra decompression | |
| CN206261657U (en) | Fusion device | |
| CN205434004U (en) | Ware is maintain to cervical vertebra transboundary intervertebral height | |
| CN212261619U (en) | Intervertebral fusion cage with memory alloy self-adaptive opening | |
| CN204618375U (en) | A kind of fracture-dislocation of cervical spine front road reduction fixation system | |
| CN201586095U (en) | Intervertebral fusion cage | |
| CN215425324U (en) | Minimally invasive implantable fusion cage | |
| CN209499987U (en) | Invasive lumbar fusion device | |
| CN211131545U (en) | Computer aided design individualized lumbar vertebra interbody fusion cage | |
| CN112089509A (en) | Integration interbody treatment fuses ware | |
| CN203388971U (en) | U-shaped titanium net interbody fusion cage | |
| KR20210002227A (en) | Expandable vertebra cage |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wu Aimin Inventor after: Chi Yonglong Inventor after: Chen Dong Inventor after: Lin Zhongke Inventor after: Ni Wenfei Inventor after: Wang Xiangyang Inventor after: Xu Huazi Inventor before: Wu Aimin Inventor before: Chi Yonglong Inventor before: Lin Zhongke Inventor before: Ni Wenfei Inventor before: Wang Xiangyang Inventor before: Xu Huazi |
|
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180206 Address after: 325000 No. 109 College West Road, Lucheng District, Zhejiang, Wenzhou Applicant after: The Second Affiliated Hospital of Wenzhou Medical University Applicant after: Wenzhou Medical University Affiliated Yuying children's Hospital Address before: 325000 Lucheng District college, Wenzhou City, Zhejiang Province, No. 109 Xili Applicant before: Wu Aimin Applicant before: Chi Yonglong Applicant before: Lin Zhongke |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |