CN105259199A - Multi-dimensional nuclear magnetic resonance fringe magnetic field imaging experimental device - Google Patents
Multi-dimensional nuclear magnetic resonance fringe magnetic field imaging experimental device Download PDFInfo
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- CN105259199A CN105259199A CN201510631230.2A CN201510631230A CN105259199A CN 105259199 A CN105259199 A CN 105259199A CN 201510631230 A CN201510631230 A CN 201510631230A CN 105259199 A CN105259199 A CN 105259199A
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Abstract
Relating to nuclear magnetic resonance imaging, the invention provides a multi-dimensional nuclear magnetic resonance fringe magnetic field imaging experimental device. The experimental device is equipped with a host computer, a PMAC controller, a spectrometer, an AC servo motor driver, four DC servo motor drivers, an AC servo motor, four DC servo motors, a fringe magnetic field imaging plane lifting platform, an imaging probe, two sample chamber Y axis motion system power transmission lines, five sample chamber rotation motion system power transmission lines, seven sample chamber up-and-down motion system power transmission lines, four sample chamber X axis motion system power transmission lines, a probe coil, and a sample chamber up-and-down motion system worm. The experimental device can realize arbitrary angle adjustment of the sample chamber, stable mechanical discontinuous rotation and relative motion of the sample chamber and the probe coil. Through combination of positioning algorithm and a precise mechanical structure, the experimental device realizes movement of the sample chamber relative to the coil, and solves the problem that existing multi-dimensional fringe magnetic field imaging probe experimental devices in the world cannot realize large size sample imaging under an ultrastrong gradient field.
Description
Technical field
The present invention relates to Magnetic resonance imaging, especially relate to a kind of multi-dimensional nmr fringe magnetic field imaging experiment device.
Background technology
Nuclear magnetic resonance fringe magnetic field imaging technique comes from phase late 1980s, compared with traditional nmr imaging technique, its outstanding feature utilizes the superpower gradient fields in superconducting magnet edge to come imaging of samples, the gradient fields that can produce due to the gradient coil that traditional core magnetic resonance fringe magnetic field equipment is used generally can only reach about 1.5T/m, much smaller than 50 ~ 60T/m of fringe magnetic field, again because the resolution of Magnetic resonance imaging and gradient strength directly related, therefore in the resolution of image, fringe magnetic field imaging technique is compared traditional core mr imaging technique tool and is improved a lot.In Magnetic resonance imaging field, solid sample due to molecule can not free movement, and there is stronger spin coupling effect, spectrum width is very wide, resolution is very poor, common way solid sample is mixed with solution measure again, and gradient fields superpower in the imaging technique of fringe magnetic field can overcome a series of insoluble problem of solid sample on conventional magnetic resonance imaging technique, realizes high-resolution solid state image.
What utilize due to fringe magnetic field imaging technique is the natural superpower gradient fields in edge of superconducting magnet, and do not need gradient coil, this is one of feature of fringe magnetic field imaging technique.Exactly because but also this feature, in current fringe magnetic field imaging technique, occupy main flow or the formation method of one dimension fringe magnetic field.The principle of multi-dimensional edge magnetic field imaging technique utilizes sample rotation in space, originally the superpower gradient fields in superconducting magnet edge in a direction will be only present in, the simulation being realized coordinate axis by the suitable rotation of sample is rotated, and realizes the sample message collection of the superpower gradient fields of three-dimensional.When surveyed sample size is larger, the aspect that excites of radio-frequency pulse cannot cover whole sample completely, and now sample just becomes very necessary relative to moving up and down of coil.In the outer disclosed patent of Present Domestic or pertinent literature, US Patent No. 005424644 describes a kind of mechanism that may be used for the imaging of multi-dimensional edge magnetic field, this mechanism achieves the pose adjustment of sample in coil, but it is when adjusting up and down sample, and the relative movement of unrealized probe and sample, but the movement of entirety, under the fringe magnetic field environment of superconducting magnet, because gradient fields is extremely strong, the significantly mobile acute variation often causing magnetic field residing for self of probe, and due to the change in magnetic field too large, uncertain factor increases, the resolution of imaging and signal to noise ratio (S/N ratio) also will be affected, also the artifact of image is easily caused.Patent WO20008833A2 and paper " Multi-dimensionalmagneticresonanceimaginginastraymagneti cfield " then describe and MAS and fringe magnetic field imaging are combined, directly sample cavity is tilted to magic angle angle, rotary sample is made in pneumatic mode, this mode reaches the effect of three-dimensional imaging, but and the movement of unrealized sample relative probe, when sample is larger, the overlay area of radio-frequency pulse does not cover the size of sample, therefore the imaging experiment of small sample can only be done, and the stability adopting pneumatic mode also to make sample cavity rotate can not be guaranteed, affect the precision of experimental result.Also has paper " ContrastSTRAFI – MASimaging ", the author of " Two-andThree-DimensionalMultinuclearStray-FieldImagingof RotatingSampleswithMagic-AngleSpinning (STRAFI-MAS) FromBiotoInorganicMaterials " also attempts ready-made Magic angle spinning commercialization probe to be applied directly in the imaging technique of fringe magnetic field and makes 3-D view, but because the Magic angle spinning probe of commercialization is mainly used for solid magnetic resonance spectrum, and non-expert is developed for fringe magnetic field imaging technique, therefore there is many deficiencies, such as can not Quality control rotating speed well, conventional Magic angle spinning probe rotational stabilization image serious distortion that is poor and that cause in the evolution phase spatial position change of gradient encode, and for example current Magic angle spinning multi-dimensional edge magnetic field imaging probe, all can not realize the relative movement of sample and coil, just there is restriction to the sample size size of imaging thus, the multi-dimensional edge magnetic field imaging of large scale sample under superpower gradient fields cannot be carried out, also arbitrarily cannot carry out the adjustment of multi-angle attitude to sample.Generally speaking, the three-dimensional edges magnetic field imaging experiment device of present stage can't realize mechanical discontinuous formula stable rotation and under carrying out superpower gradient fields during the imaging of large scale solid sample sample cavity relative to the movement of probe coil.
Summary of the invention
The object of the present invention is to provide a kind of multi-dimensional nmr fringe magnetic field imaging experiment device.
The present invention is provided with host computer, PMAC controller, spectrometer, an AC servo machinery driving device, four DC servo motor drivers, an AC servo motor, four DC servo motor, fringe magnetic field imaging plane lifting table, High Resolution Solid State rate imaging probe, sample cavity Y-axis kinematic system power transmission circuit one, sample cavity rotary motion system dynamic transmits circuit one, sample cavity move up and down system dynamic transmit circuit one, sample cavity X-axis kinematic system power transmission circuit one, sample cavity move up and down system dynamic transmit circuit two, sample cavity X-axis kinematic system power transmission circuit two, sample cavity Y-axis kinematic system power transmission circuit two, sample cavity move up and down system dynamic transmit circuit seven, sample cavity X-axis kinematic system power transmission circuit three, probe coil, sample cavity X-axis kinematic system power transmission circuit four, sample cavity X-axis kinematic system power transmission circuit five, sample cavity, sample cavity move up and down system dynamic transmit circuit five, sample cavity rotary motion system dynamic transmits circuit four, sample cavity rotary motion system dynamic transmits circuit five, sample cavity move up and down system dynamic transmit circuit six, sample cavity move up and down system dynamic transmit circuit four, sample cavity rotary motion system dynamic transmits circuit three, sample cavity rotary motion system dynamic transmits circuit two, sample cavity move up and down system dynamic transmit circuit three, sample cavity moves up and down system worm screw,
Described host computer is connected with spectrometer, PMAC motion controller respectively by cable, spectrometer to be popped one's head in high resolving power solid state image by cable and is connected, PMAC motion controller is connected with four DC servo motor drivers with an AC servo machinery driving device respectively by cable, an AC servo machinery driving device is connected with an AC servo motor by cable, it is peripheral that AC servo motor is positioned over fringe magnetic field imaging plane lifting table, and AC servo motor connects power source by gear train; Four DC servo motor drivers are connected with four DC servo motor respectively by cable, and four DC servo motor are placed on the imaging plane lifting table of fringe magnetic field and to be positioned at High Resolution Solid State rate imaging probe inner;
Described High Resolution Solid State rate imaging probe is fixed on the imaging plane lifting table of fringe magnetic field, described sample cavity is placed in probe coil, owing to placing four DC servo motor bottom High Resolution Solid State rate imaging probe, so can be moved up and down system by Poewr transmission mechanism Quality control chamber X-axis kinematic system, sample cavity Y-axis kinematic system, sample cavity rotary motion system and sample cavity;
Wherein sample cavity X-axis kinematic system forms a complete power transmission circuit by sample cavity X-axis kinematic system power transmission circuit one, sample cavity X-axis kinematic system power transmission circuit two, sample cavity X-axis kinematic system power transmission circuit three, sample cavity X-axis kinematic system power transmission circuit four and sample cavity X-axis kinematic system power transmission circuit five successively; Sample cavity Y-axis kinematic system forms a complete power transmission circuit by sample cavity Y-axis kinematic system power transmission circuit one and sample cavity Y-axis kinematic system power transmission circuit two successively; The sample cavity system that moves up and down is transmitted circuit one, sample cavity to be moved up and down that system dynamic transmits circuit two, sample cavity moves up and down system dynamic transmits circuit three, sample cavity moves up and down system dynamic transmits circuit four, sample cavity moves up and down system dynamic transmits circuit five, sample cavity moves up and down system dynamic transmits circuit six, sample cavity moves up and down system dynamic transmits circuit seven forms a complete power transmission circuit by the sample cavity system dynamic that moves up and down successively; Sample cavity rotary motion system transmits circuit one by sample cavity rotary motion system dynamic successively, sample cavity rotary motion system dynamic transmits circuit two, sample cavity rotary motion system dynamic transmits circuit three, sample cavity rotary motion system dynamic transmits circuit four and sample cavity rotary motion system dynamic and transmits circuit five and form a complete power transmission circuit.
When carrying out the imaging of one dimension fringe magnetic field, instruction is sent by host computer, control an AC servo motor job via the PMAC motion controller be attached thereto, an AC servo machinery driving device, and then drive the fringe magnetic field imaging plane lifting table being equipped with high-resolution solid state image probe to move to the imaging plane of specifying.Now, experimenter starts the horizontal adjustment of carrying out sample, due to the scrambling of superconducting magnet fringe magnetic field, the appointment imaging plane that fringe magnetic field imaging plane lifting table arrives not is proper level, often there is the deviation in some angles, if now do not adjusted the attitude of sample, have great impact to the resolution of imaging, and then affect the image quality of sample, be therefore necessary to this step of sample level-off.Experimenter from host computer according to described fringe magnetic field imaging plane contour map, send command adapted thereto to PMAC motion controller, signal is passed to wherein two motors of Quality control chamber X-axis kinematic system and sample cavity Y-axis kinematic system in four direct current generators by PMAC motion controller, the motor power transfer route of Quality control chamber X-axis kinematic system is by sample cavity X-axis kinematic system power transmission circuit one in figure, sample cavity X-axis kinematic system power transmission circuit two, sample cavity X-axis kinematic system power transmission circuit three, sample cavity X-axis kinematic system power transmission circuit four and sample cavity X-axis kinematic system power transmission circuit five complete, drive sample cavity in the motion of X-axis, the motor power transfer route of Quality control chamber Y-axis kinematic system is completed by sample cavity Y-axis kinematic system power transmission circuit one in figure and sample cavity Y-axis kinematic system power transmission circuit two, drive sample cavity in the motion of Y-axis, the horizontal level that such two-axle interlocking realizes sample regulates.Then experimenter sends command adapted thereto to PMAC motion controller by host computer, signal is passed to Quality control chamber in four direct current generators and to be moved up and down the motor of system by PMAC motion controller, Quality control chamber move up and down system motor power transfer route by sample cavity in figure move up and down system dynamic transmit circuit one, sample cavity move up and down system dynamic transmit circuit two, sample cavity move up and down system dynamic transmit circuit three, sample cavity move up and down system dynamic transmit circuit four, sample cavity move up and down system dynamic transmit circuit five, sample cavity move up and down system dynamic transmit circuit six, sample cavity move up and down system dynamic transmit circuit seven complete, wherein the final tache of power transmission drives moving up and down of sample cavity by the cooperation of turbine and worm, by sample cavity to appointment starting point.Now, experimenter sends the special pulse sequence program of high resolving power solid state image to spectrometer by host computer, spectrometer sends signal to probe coil by cable again, the slow upward/downward movement of sample cavity, the mobile intensity difference that will make echoed signal under sample cavity, according to the difference of echo signal intensity, again through the data processing in later stage, then can obtain one dimension fringe magnetic field image, if the signal gathered is not ideal enough, then by the sample cavity system that moves up and down, sample cavity can be return reference point, Resurvey signal.
When carrying out the experiment of two-dimensional/three-dimensional fringe magnetic field imaging Magic angle spinning, instruction is sent by host computer, control an AC servo motor job via the PMAC motion controller be attached thereto, an AC servo machinery driving device, and then drive the fringe magnetic field imaging plane lifting table being equipped with high-resolution solid state image probe to move to the imaging plane of specifying.Then experimenter from host computer according to described fringe magnetic field imaging plane contour map, because the fringe magnetic field of superconducting magnet is irregular, the direction of static magnetic field is not be strictly perpendicular to surface level, so the good image of imaging effect will be obtained, it is not accurate enough for being only adjusted to vertical direction angle 54.7 ° by sample cavity, and should be the magic angular direction of 54.7 ° with the angular separation of static magnetic field.Experimenter sends command adapted thereto to PMAC motion controller by host computer, signal is passed to wherein two motors of Quality control chamber X-axis kinematic system and sample cavity Y-axis kinematic system in four direct current generators by PMAC motion controller, the motor power transfer route of Quality control chamber X-axis kinematic system is by sample cavity X-axis kinematic system power transmission circuit one in figure, sample cavity X-axis kinematic system power transmission circuit two, sample cavity X-axis kinematic system power transmission circuit three, sample cavity X-axis kinematic system power transmission circuit four and sample cavity X-axis kinematic system power transmission circuit five complete, drive sample cavity in the motion of X-axis, the motor power transfer route of Quality control chamber Y-axis kinematic system is completed by sample cavity Y-axis kinematic system power transmission circuit one in figure and sample cavity Y-axis kinematic system power transmission circuit two, drive sample cavity in the motion of Y-axis, the magic Angle Position that such two-axle interlocking realizes sample regulates.Then experimenter sends command adapted thereto to PMAC motion controller by host computer, signal is passed to the motor of rotary motion system in Quality control chamber in four direct current generators by PMAC motion controller, the motor power transfer route of Quality control chamber rotary motion system transmits circuit one by sample cavity rotary motion system dynamic in figure, sample cavity rotary motion system dynamic transmits circuit two, sample cavity rotary motion system dynamic transmits circuit three, sample cavity rotary motion system dynamic transmits circuit four and sample cavity rotary motion system dynamic transmission circuit five completes, sample cavity is made to complete the action of rotation.Now, experimenter sends the special pulse sequence program of high resolving power solid state image to spectrometer by host computer, spectrometer sends signal to probe coil by cable again, sample cavity now still keeps rotary motion constant, according to the echo information of pulse train, advanced image reconstruction algorithm again through being integrated in host computer, generates two-dimensional/three-dimensional image information.When due to the rotating speed of sample cavity is too fast or other factors cause data acquisition results undesirable time, advanced rotating speed control algolithm integrated in host computer, the mode that rotation can be made to realize mechanical discontinuous formula is moved, even can realize reversion to gather the information needed for supplementary two-dimensional/three-dimensional image, this is also of the present invention one large feature.When carrying out the two-dimensional/three-dimensional imaging experiment of large-size sample under superpower gradient fields, the bandwidth that radio-frequency pulse produces is not sufficient to cover whole sample, now just need while sample cavity rotates, slow movement relative to probe coil is carried out to sample cavity, experimenter sends command adapted thereto to PMAC motion controller by host computer, signal is passed to Quality control chamber in four direct current generators and to be moved up and down the motor of system by PMAC motion controller, Quality control chamber move up and down system motor power transfer route by sample cavity in figure move up and down system dynamic transmit circuit one, sample cavity move up and down system dynamic transmit circuit two, sample cavity move up and down system dynamic transmit circuit three, sample cavity move up and down system dynamic transmit circuit four, sample cavity move up and down system dynamic transmit circuit five, sample cavity move up and down system dynamic transmit circuit six, sample cavity move up and down system dynamic transmit circuit seven complete, above-mentioned sample cavity rotary motion is coordinated to realize the two-dimensional/three-dimensional fringe magnetic field imaging of large scale sample under superpower gradient fields.
Experimental provision of the present invention can realize the arbitrarily angled adjustment of sample cavity, the discontinuous formula of stable machinery rotates and the relative motion of sample cavity and probe coil.
Described host computer is integrated with advanced High Resolution Solid State rate imaging pulse sequence and the positional control algorithm of multiple advanced person, is connected with described spectrometer system, described PMAC motion control card respectively by cable.
Described PMAC motion control card is connected with described motor servo driver by cable, and described motor servo driver is connected with servomotor by cable again.
Described High Resolution Solid State rate imaging probe is fixed on the imaging plane lifting table of described fringe magnetic field, described sample cavity is placed in High Resolution Solid State rate imaging probe, place described servomotor bottom High Resolution Solid State rate imaging probe, servomotor controls described sample cavity X-axis kinematic system, described sample cavity Y-axis kinematic system, described sample cavity rotary motion system and described sample cavity by Poewr transmission mechanism again and to move up and down system.
The present invention is except control system, and the parts within nmr magnet gaussian line all adopt non-magnetic material to make, and to avoid the impact on magnetic field, causes the inaccurate of experimental result.Sample cavity X-axis kinematic system of the present invention, sample cavity Y-axis kinematic system, sample cavity rotary motion system, the sample cavity system that moves up and down all have oneself a set of power resources, do not interfere with each other.
When carrying out multi-dimensional edge magnetic field imaging experiment, described host computer sends instruction to described PMAC motion control card, PMAC card sends instruction to described motor servo driver, motor servo driver sends signal and makes described servomotor work, servomotor makes described fringe magnetic field imaging plane lifting table reach assigned address by a series of physical construction, now, instruction is sent to motor servo driver by the PMAC motion control card of PC control, control the servomotor motion bottom described High Resolution Solid State rate imaging probe, servomotor drives described sample cavity X-axis control system, sample cavity Y-axis kinematic system works, adjustment sample cavity is to required angle, sample cavity X-axis and sample cavity Y-axis two-axle interlocking can be made by described PMAC motion controller time necessary, to reaching best imaging effect.
After the angle of described sample cavity is determined, visual exam situation, instruction is sent to described PMAC motion control card by described host computer, PMAC motion control card sends instruction to described motor servo driver, motor servo driver controls the servomotor work bottom described High Resolution Solid State rate imaging probe, servomotor can drive described sample cavity rotary motion system or sample cavity to move up and down system works, sample cavity is rotated or moving up and down relative to described High Resolution Solid State rate imaging probe, two-axle interlocking can be realized if desired by described PMAC motion controller, the rotary motion of sample cavity is carried out with relative moving up and down simultaneously, with satisfied experiment demand.
When sample cavity moves, described host computer sends High Resolution Solid State rate imaging pulse sequence by described spectrometer to described High Resolution Solid State rate imaging probe.
Main innovate point of the present invention is: combined by the location algorithm of advanced person and accurate machine construction, achieve the movement of sample cavity relative to coil, solve the problem that current existing multi-dimensional edge magnetic field in the world imaging probe experimental provision cannot realize large scale sample imaging under superpower gradient fields; The control algolithm that utilization is advanced and accurate machine construction combine and achieve any rotating speed control of sample cavity rotation, and the mode of the discontinuous rotation of this machinery effectively prevent conventional Magic angle spinning probe rotational stabilization image serious distortion that is poor and that cause in the evolution phase spatial position change of gradient encode; By the combination of advanced sample cavity attitude-simulating algorithm and PMAC motion control card, achieve the Dual-spindle linked of experiment described sample cavity X-axis kinematic system in early stage, sample cavity Y-axis kinematic system, coordinate the described sample cavity rotary motion system of Dual-spindle linked again, sample cavity moves up and down system, the present invention is made to have versatility, namely the one dimension fringe magnetic field imaging experiment of current main flow can be realized, also can realize two-dimensional/three-dimensional fringe magnetic field imaging experiment, overcome current multi-dimensional edge magnetic field imaging device and use the deficiency that means are comparatively single.
Accompanying drawing explanation
Fig. 1 is embodiment of the present invention overall framework schematic diagram.
Fig. 2 is the invention process High Resolution Solid State rate imaging probe inner detailed maps, i.e. solid box I part in Fig. 1.
Fig. 3 is embodiment of the present invention High Resolution Solid State rate imaging probe the first half detailed maps, i.e. solid box II part in Fig. 2.
Embodiment
Below with reference to accompanying drawing, the present invention is described in detail.
As shown in Figures 1 to 3, the embodiment of the present invention is provided with host computer 1, PMAC controller 2, spectrometer 3, an AC servo machinery driving device 4, four DC servo motor drivers 5, an AC servo motor 6, four DC servo motor 7, fringe magnetic field imaging plane lifting table 8, High Resolution Solid State rate imaging probe 9, sample cavity Y-axis kinematic system power transmission circuit 1, sample cavity rotary motion system dynamic transmits circuit 1, sample cavity move up and down system dynamic transmit circuit 1, sample cavity X-axis kinematic system power transmission circuit 1, sample cavity move up and down system dynamic transmit circuit 2 14, sample cavity X-axis kinematic system power transmission circuit 2 15, sample cavity Y-axis kinematic system power transmission circuit 2 16, sample cavity move up and down system dynamic transmit circuit 7 17, sample cavity X-axis kinematic system power transmission circuit 3 18, probe coil 19, sample cavity X-axis kinematic system power transmission circuit 4 20, sample cavity X-axis kinematic system power transmission circuit 5 21, sample cavity 22, sample cavity move up and down system dynamic transmit circuit 5 23, sample cavity rotary motion system dynamic transmits circuit 4 24, sample cavity rotary motion system dynamic transmits circuit 5 25, sample cavity move up and down system dynamic transmit circuit 6 26, sample cavity move up and down system dynamic transmit circuit 4 27, sample cavity rotary motion system dynamic transmits circuit 3 28, sample cavity rotary motion system dynamic transmits circuit 2 29, sample cavity move up and down system dynamic transmit circuit 3 30, sample cavity moves up and down system worm screw 31,
Described host computer 1 is connected with spectrometer 3, PMAC motion controller 2 respectively by cable, spectrometer 3 is popped one's head in by cable and high resolving power solid state image and 9 to be connected, PMAC motion controller 2 is connected with four DC servo motor drivers 5 with an AC servo machinery driving device 4 respectively by cable, an AC servo machinery driving device 4 is connected with an AC servo motor 6 by cable, it is peripheral that AC servo motor 6 is positioned over fringe magnetic field imaging plane lifting table 8, and AC servo motor 6 connects power source by gear train; Four DC servo motor drivers 5 are connected with four DC servo motor 7 respectively by cable, and four DC servo motor 7 are placed on fringe magnetic field imaging plane lifting table 8 and to be positioned at High Resolution Solid State rate imaging probe 9 inner;
Described High Resolution Solid State rate imaging probe 9 is fixed on fringe magnetic field imaging plane lifting table 8, described sample cavity 22 is placed in probe coil 19, owing to placing four DC servo motor 7 bottom High Resolution Solid State rate imaging probe 9, so can be moved up and down system by Poewr transmission mechanism Quality control chamber X-axis kinematic system, sample cavity Y-axis kinematic system, sample cavity rotary motion system and sample cavity;
Wherein sample cavity X-axis kinematic system forms a complete power transmission circuit by sample cavity X-axis kinematic system power transmission circuit 1, sample cavity X-axis kinematic system power transmission circuit 2 15, sample cavity X-axis kinematic system power transmission circuit 3 18, sample cavity X-axis kinematic system power transmission circuit 4 20 and sample cavity X-axis kinematic system power transmission circuit 5 21 successively, sample cavity Y-axis kinematic system forms a complete power transmission circuit by sample cavity Y-axis kinematic system power transmission circuit 1 and sample cavity Y-axis kinematic system power transmission circuit 2 16 successively, sample cavity move up and down system successively by sample cavity move up and down system dynamic transmit circuit 1, sample cavity move up and down system dynamic transmit circuit 2 14, sample cavity move up and down system dynamic transmit circuit 3 30, sample cavity move up and down system dynamic transmit circuit 4 27, sample cavity move up and down system dynamic transmit circuit 5 23, sample cavity move up and down system dynamic transmit circuit 6 26, the sample cavity system dynamic that moves up and down transmits circuit 7 17 and forms a complete power transmission circuit, sample cavity rotary motion system transmits circuit 1 by sample cavity rotary motion system dynamic successively, sample cavity rotary motion system dynamic transmits circuit 2 29, sample cavity rotary motion system dynamic transmits circuit 3 28, sample cavity rotary motion system dynamic transmits circuit 4 24 and sample cavity rotary motion system dynamic and transmits circuit 5 25 and form a complete power transmission circuit.
When carrying out the imaging of one dimension fringe magnetic field, instruction is sent by host computer 1, control an AC servo motor 6 via the PMAC motion controller be attached thereto 2, AC servo machinery driving device 4 to work, and then drive the fringe magnetic field imaging plane lifting table 8 being equipped with high-resolution solid state image probe 9 to move to the imaging plane of specifying.Now, experimenter starts the horizontal adjustment of carrying out sample, due to the scrambling of superconducting magnet fringe magnetic field, the appointment imaging plane that fringe magnetic field imaging plane lifting table 8 arrives not is proper level, often there is the deviation in some angles, if now do not adjusted the attitude of sample, have great impact to the resolution of imaging, and then affect the image quality of sample, be therefore necessary to this step of sample level-off.Experimenter from host computer 1 according to described fringe magnetic field imaging plane contour map, send command adapted thereto to PMAC motion controller 2, signal is passed to wherein two motors of Quality control chamber X-axis kinematic system and sample cavity Y-axis kinematic system in four direct current generators 4 by PMAC motion controller 2, the motor power transfer route of Quality control chamber X-axis kinematic system is by sample cavity X-axis kinematic system power transmission circuit 1 in figure, sample cavity X-axis kinematic system power transmission circuit 2 15, sample cavity X-axis kinematic system power transmission circuit 3 18, sample cavity X-axis kinematic system power transmission circuit 4 20 and sample cavity X-axis kinematic system power transmission circuit 5 21 complete, drive sample cavity in the motion of X-axis, the motor power transfer route of Quality control chamber Y-axis kinematic system is completed by sample cavity Y-axis kinematic system power transmission circuit 1 in figure and sample cavity Y-axis kinematic system power transmission circuit 2 16, drive sample cavity in the motion of Y-axis, the horizontal level that such two-axle interlocking realizes sample regulates.Then experimenter sends command adapted thereto to PMAC motion controller 2 by host computer 1, signal is passed to Quality control chamber in four direct current generators 4 and to be moved up and down the motor of system by PMAC motion controller 2, Quality control chamber move up and down system motor power transfer route by sample cavity in figure move up and down system dynamic transmit circuit 1, sample cavity move up and down system dynamic transmit circuit 2 14, sample cavity move up and down system dynamic transmit circuit 3 30, sample cavity move up and down system dynamic transmit circuit 4 27, sample cavity move up and down system dynamic transmit circuit 5 23, sample cavity move up and down system dynamic transmit circuit 6 26, sample cavity move up and down system dynamic transmit circuit 7 17 complete, wherein the final tache of power transmission drives moving up and down of sample cavity by the cooperation of turbine and worm, by sample cavity 22 to specifying starting point.Now, experimenter sends the special pulse sequence program of high resolving power solid state image to spectrometer 3 by host computer 1, spectrometer 3 sends signal to probe coil 19 by cable again, the slow upward/downward movement of sample cavity, sample cavity 22 times movements will make the intensity of echoed signal different, according to the difference of echo signal intensity, again through the data processing in later stage, then can obtain one dimension fringe magnetic field image, if the signal gathered is not ideal enough, then by the sample cavity system that moves up and down, sample cavity can be return reference point, Resurvey signal.
When carrying out the experiment of two-dimensional/three-dimensional fringe magnetic field imaging Magic angle spinning, instruction is sent by host computer 1, control an AC servo motor 6 via the PMAC motion controller be attached thereto 2, AC servo machinery driving device 4 to work, and then drive the fringe magnetic field imaging plane lifting table 8 being equipped with high-resolution solid state image probe 9 to move to the imaging plane of specifying.Then experimenter from host computer 1 according to described fringe magnetic field imaging plane contour map, because the fringe magnetic field of superconducting magnet is irregular, the direction of static magnetic field is not be strictly perpendicular to surface level, so the good image of imaging effect will be obtained, it is not accurate enough for being only adjusted to vertical direction angle 54.7 ° by sample cavity, and should be the magic angular direction of 54.7 ° with the angular separation of static magnetic field.Experimenter sends command adapted thereto to PMAC motion controller 2 by host computer 1, signal is passed to wherein two motors of Quality control chamber X-axis kinematic system and sample cavity Y-axis kinematic system in four direct current generators 4 by PMAC motion controller 2, the motor power transfer route of Quality control chamber X-axis kinematic system is by sample cavity X-axis kinematic system power transmission circuit 1 in figure, sample cavity X-axis kinematic system power transmission circuit 2 15, sample cavity X-axis kinematic system power transmission circuit 3 18, sample cavity X-axis kinematic system power transmission circuit 4 20 and sample cavity X-axis kinematic system power transmission circuit 5 21 complete, drive sample cavity in the motion of X-axis, the motor power transfer route of Quality control chamber Y-axis kinematic system is completed by sample cavity Y-axis kinematic system power transmission circuit 1 in figure and sample cavity Y-axis kinematic system power transmission circuit 2 16, drive sample cavity in the motion of Y-axis, the magic Angle Position that such two-axle interlocking realizes sample regulates.Then experimenter sends command adapted thereto to PMAC motion controller 2 by host computer 1, signal is passed to the motor of rotary motion system in Quality control chamber in four direct current generators 4 by PMAC motion controller 2, the motor power transfer route of Quality control chamber rotary motion system transmits circuit 1 by sample cavity rotary motion system dynamic in figure, sample cavity rotary motion system dynamic transmits circuit 2 29, sample cavity rotary motion system dynamic transmits circuit 3 28, sample cavity rotary motion system dynamic transmits circuit 4 24 and sample cavity rotary motion system dynamic transmission circuit 5 25 completes, sample cavity is made to complete the action of rotation.Now, experimenter sends the special pulse sequence program of high resolving power solid state image to spectrometer 3 by host computer 1, spectrometer 3 sends signal to probe coil 19 by cable again, sample cavity now still keeps rotary motion constant, according to the echo information of pulse train, advanced image reconstruction algorithm again through being integrated in host computer 1, generates two-dimensional/three-dimensional image information.When due to the rotating speed of sample cavity is too fast or other factors cause data acquisition results undesirable time, advanced rotating speed control algolithm integrated in host computer 1, the mode that rotation can be made to realize mechanical discontinuous formula is moved, even can realize reversion to gather the information needed for supplementary two-dimensional/three-dimensional image, this is also of the present invention one large feature.When carrying out the two-dimensional/three-dimensional imaging experiment of large-size sample under superpower gradient fields, the bandwidth that radio-frequency pulse produces is not sufficient to cover whole sample, now just need while sample cavity rotates, slow movement relative to probe coil 19 is carried out to sample cavity, experimenter sends command adapted thereto to PMAC motion controller 2 by host computer 1, signal is passed to Quality control chamber in four direct current generators 4 and to be moved up and down the motor of system by PMAC motion controller 2, Quality control chamber move up and down system motor power transfer route by sample cavity in figure move up and down system dynamic transmit circuit 1, sample cavity move up and down system dynamic transmit circuit 2 14, sample cavity move up and down system dynamic transmit circuit 3 30, sample cavity move up and down system dynamic transmit circuit 4 27, sample cavity move up and down system dynamic transmit circuit 5 23, sample cavity move up and down system dynamic transmit circuit 6 26, sample cavity move up and down system dynamic transmit circuit 7 17 complete, above-mentioned sample cavity rotary motion is coordinated to realize the two-dimensional/three-dimensional fringe magnetic field imaging of large scale sample under superpower gradient fields.
Claims (1)
1. multi-dimensional nmr fringe magnetic field imaging experiment device, is characterized in that being provided with host computer, PMAC controller, spectrometer, an AC servo machinery driving device, four DC servo motor drivers, an AC servo motor, four DC servo motor, fringe magnetic field imaging plane lifting table, solid state image is popped one's head in, sample cavity Y-axis kinematic system power transmission circuit one, sample cavity rotary motion system dynamic transmits circuit one, sample cavity move up and down system dynamic transmit circuit one, sample cavity X-axis kinematic system power transmission circuit one, sample cavity move up and down system dynamic transmit circuit two, sample cavity X-axis kinematic system power transmission circuit two, sample cavity Y-axis kinematic system power transmission circuit two, sample cavity move up and down system dynamic transmit circuit seven, sample cavity X-axis kinematic system power transmission circuit three, probe coil, sample cavity X-axis kinematic system power transmission circuit four, sample cavity X-axis kinematic system power transmission circuit five, sample cavity, sample cavity move up and down system dynamic transmit circuit five, sample cavity rotary motion system dynamic transmits circuit four, sample cavity rotary motion system dynamic transmits circuit five, sample cavity move up and down system dynamic transmit circuit six, sample cavity move up and down system dynamic transmit circuit four, sample cavity rotary motion system dynamic transmits circuit three, sample cavity rotary motion system dynamic transmits circuit two, sample cavity move up and down system dynamic transmit circuit three, sample cavity moves up and down system worm screw,
Described host computer is connected with spectrometer, PMAC motion controller respectively by cable, spectrometer to be popped one's head in solid state image by cable and is connected, PMAC motion controller is connected with four DC servo motor drivers with an AC servo machinery driving device respectively by cable, an AC servo machinery driving device is connected with an AC servo motor by cable, it is peripheral that AC servo motor is positioned over fringe magnetic field imaging plane lifting table, and AC servo motor connects power source by gear train; Four DC servo motor drivers are connected with four DC servo motor respectively by cable, and four DC servo motor are placed on the imaging plane lifting table of fringe magnetic field and to be positioned at solid state image probe inner;
Described solid state image probe is fixed on the imaging plane lifting table of fringe magnetic field, and described sample cavity is placed in probe coil;
Sample cavity X-axis kinematic system forms a complete power transmission circuit by sample cavity X-axis kinematic system power transmission circuit one, sample cavity X-axis kinematic system power transmission circuit two, sample cavity X-axis kinematic system power transmission circuit three, sample cavity X-axis kinematic system power transmission circuit four and sample cavity X-axis kinematic system power transmission circuit five successively; Sample cavity Y-axis kinematic system forms a complete power transmission circuit by sample cavity Y-axis kinematic system power transmission circuit one and sample cavity Y-axis kinematic system power transmission circuit two successively; The sample cavity system that moves up and down is transmitted circuit one, sample cavity to be moved up and down that system dynamic transmits circuit two, sample cavity moves up and down system dynamic transmits circuit three, sample cavity moves up and down system dynamic transmits circuit four, sample cavity moves up and down system dynamic transmits circuit five, sample cavity moves up and down system dynamic transmits circuit six, sample cavity moves up and down system dynamic transmits circuit seven forms a complete power transmission circuit by the sample cavity system dynamic that moves up and down successively; Sample cavity rotary motion system transmits circuit one by sample cavity rotary motion system dynamic successively, sample cavity rotary motion system dynamic transmits circuit two, sample cavity rotary motion system dynamic transmits circuit three, sample cavity rotary motion system dynamic transmits circuit four and sample cavity rotary motion system dynamic and transmits circuit five and form a complete power transmission circuit.
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