CN105248439B

CN105248439B - Plant disease control composition and the method for control for applying its plant disease

Info

Publication number: CN105248439B
Application number: CN201510821356.6A
Authority: CN
Inventors: 玉川靖; 石本洋; 高木麻由美; 小原敏明; 田中治; 田中治一
Original assignee: Sankyo Agro Co Ltd
Current assignee: Mitsui Chemical Plant Protection Co ltd
Priority date: 2009-12-22
Filing date: 2009-12-22
Publication date: 2017-11-14
Anticipated expiration: 2029-12-22
Also published as: CN105248439A; CN105265437A; CN105325423A; CN105409967A; CN105409967B; CN105325435B; CN105475283A; CN105325423B; CN105325435A; CN105265437B

Abstract

The present invention relates to the method for control of its plant disease of plant disease control composition and administration, the plant disease control composition has multiple diseases spectrum to various plants pathogen, shows the excellent preventive effect (preventive effect of collaboration) that can not be expected by separate constituent.The plant disease control composition of the present invention is characterised by, containing selected from (a-14) 3- (5- fluoro- 3, 3, 4, 4- tetramethyls -3, 4- dihydro-isoquinoline -1- bases) quinoline, (a-18) 3- (4, 4- bis- fluoro- 3, 3- dimethyl -3, 4- dihydro-isoquinoline -1- bases) quinoline, and (a-20) 3- (4, 4, 5- tri- fluoro- 3, 3- dimethyl -3, 4- dihydro-isoquinoline -1- bases) at least one of quinoline quinoline compound or its salt (group a), and bactericidal properties compound (b-15-2) thiophanate methyl is as active ingredient.

Description

Plant disease control composition and the method for control for applying its plant disease

The application is the applying date, and on December 22nd, 2009, Application No. 200980163141.2, (international application no is PCT/JP2009/071287), entitled " plant disease control composition and the method for control for applying its plant disease " Application divisional application.

Technical field

The present invention relates to plant disease control composition and the method for control for the plant disease for applying said composition, the plant Thing disease is prevented and kill off composition and is characterised by, at least one kind of quinoline compound represented containing logical formula (I) or its salt (group a) and choosing More than a kind of bactericidal properties compound in the group of 1 (b-1)~28 (b-28) (group b) composition is freely organized as active ingredient.

Background technology

All the time, substantial amounts of chemicals is used for plant disease control.But due to the same work with similar skeleton It is frequently used or overdose etc. with the chemicals for being to prevent and kill off disease of the same race, and causes phytopathogen to chemical drugs The patience problem of thing is more and more significant.

On the other hand, recent consumer is to subtracting the demand of agricultural chemicals crop and to mitigating the carrying capacity of environment as caused by chemical pesticide Social demand more and more higher.

In addition, in the agriculture garden as medicine field of employment, (tank mixing) method is mixed with tank and uses two or more medicine with When being handled, for the combination between the medicine of poor compatibility, the effect that each medicine more be present is reduced or made The danger of poisoning occurs for plant.

In these cases, expect even for the resistant bacterium to existing medicine also have efficiently, active ingredient amount it is relatively low and The high plant disease control composition of effect.Also, in order to prevent the patience of phytopathogen, it is also desirable to develop by with The good plant disease control composition of compatibility that different composition (compound) basic framework, that functionality is different is formed and Method for controlling plant disease.

The quinoline compound that known logical formula (I) represents is applied as bactericide using seed disinfection, cauline leaf distribution processing etc. Method is to the rice blast (Pyricularia oryzae) of rice and the gray mold (Botrytis of tomato, cucumber and Kidney bean The display preventive effect (patent document 1~4) such as cinerea).

But the quinoline compound represented for leading to formula (I) mix with other bactericide caused by preventive effect, still belong to It is unknown.

Patent document 1：No. 2005/070917 specification of International Publication (WO)

Patent document 2：Japanese Unexamined Patent Publication 2007-1944 publications

Patent document 3：No. 2007/011022 specification of International Publication (WO)

Patent document 4：Japanese Unexamined Patent Publication 2007-217353 publications

The content of the invention

The combination of quinoline compound and other microbiocidal compositions that the mutual-through types such as the present inventor (I) represent is studied, As a result find, by the way that the quinoline compound that logical formula (I) represents is combined with specific bactericidal properties compound, to various plants cause of disease The available preventive effect (synergy) can not being expected by separate constituent, excellent of bacterium, also, even if to existing resistant bacterium Stable preventive effect is shown, and does not find the generation of poisoning, so as to complete the present invention.

Composition is prevented and kill off it is an object of the invention to provide novel plant disease and applies the plant disease of said composition The method of control, the plant disease control composition has multiple diseases spectrum to various phytopathogens, even for existing The resistant bacterium of medicine displays that high plant disease control effect, low even if the active ingredient amount given to pathogen habitat High activity is shown, and does not find to produce poisoning to plant.

The present invention relates to a kind of plant disease control composition, it is characterised in that leads at least the 1 of formula (I) expression containing (a) Be selected from the group (organizing b) be made up of following groups (1)~(28) more than a kind of kind of quinoline compound or its salt (group a) and (b) kills Bacterium property compound as active ingredient,

[in formula, R¹And R²It can be the same or different, represent

C₁~C₆Alkyl, free halogen, C can be chosen₁~C₆Alkoxy, C₁~C₆In the group of alkylthio group and phenoxy group composition The substitution of identical or different 1~3 substituent；

Aryl, free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl, C₁ ~C₆Alkoxy, can be by 1~2 identical or different C₁~C₆Alkyl or amino, nitro, cyano group, hydroxyl, the mercapto of acyl group substitution Base and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkylthio group composition；

Heteroaryl, free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkoxy composition；Or

Aralkyl, free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl, C₁~C₆Alkoxy, can be by 1~2 identical or different C₁~C₆Alkyl or acyl group substitution amino, nitro, cyano group, hydroxyl, Sulfydryl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkylthio group composition；Or

R¹And R²C is formed together with the carbon atom being bonded with them₃~C₁₀Cycloalkyl ring, the C₃~C₁₀Cycloalkyl ring can Selected free halogen, C₁~C₆Alkyl, C₁~C₆Identical or different 1~3 in the group of alkoxy and phenoxy group composition takes Substitute for base；

R³And R⁴It can be the same or different, represent

Hydrogen atom；

Halogen atom；

C₁~C₆Alkoxy；Or

Hydroxyl；Or

R³And R⁴C is formed together₁~C₆Alkylidene or oxo (oxo) base, or

C is formed together with the carbon atom being bonded with them₃~C₁₀Cycloalkyl ring, the C₃~C₁₀Cycloalkyl ring can by selected from By halogen atom, C₁~C₆Alkyl, C₁~C₆Identical or different 1~3 substituent in the group of alkoxy and phenoxy group composition takes Generation；

When n is 2~4, X can be the same or different, and represent

Halogen atom；

C₁~C₆Alkyl, free halogen, C can be chosen₁~C₆Alkoxy, hydroxyl, C₂~C₇Alkoxy carbonyl and phenoxy group Identical or different 1~3 substituent substitution in the group of composition；

C₂~C₆Alkenyl, free halogen, C can be chosen₁~C₆Alkoxy, C₂~C₇Alkoxy carbonyl and phenoxy group composition Group in the substitution of identical or different 1~3 substituent；

C₂~C₆Alkynyl, free halogen, C can be chosen₁~C₆It is identical or different in the group of alkoxy and phenoxy group composition 1~3 substituent substitution；

Heteroaryl, free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkoxy composition；

C₁~C₆Alkoxy；

Amino, can be by 1~2 identical or different C₁~C₆Alkyl or acyl group substitution；

Acyl group；

Cyano group；Or

N- hydroxyls C₁~C₆Alkane imino group, wherein, the hydrogen atom of hydroxyl can be chosen free C₁~C₆Alkyl, C₂~C₆Chain Alkenyl, C₂~C₆Substituent substitution in the group that alkynyl, aralkyl, aryl and heteroaryl form；

When m is 2~6, Y can be the same or different, and represent

Halogen atom；C₁~C₆Alkyl；C₁~C₆Alkoxy；Or hydroxyl；

N is represented, 0~4 integer,

M represents 0~6 integer]

Group (1)：

Selected from (b-1-1) nitrile Fluoxastrobin (Azoxystrobin),

(b-1-2) imines bacterium (Kresoxim-methyl),

(b-1-3) pyraclostrobin (Pyraclostrobin),

(b-1-4) ZEN 90160 (Picoxystrobin),

(b-1-5) fluoxastrobin (Fluoxastrobin),

(b-1-6) dimoxystrobin (Dimoxystrobin),

(b-1-7) orysastrobin (Orysastrobin),

(b-1-8) pitch phenalgin acid amides (Metominostrobin) and

(b-1-9) trifloxystrobin (Trifloxystrobin)

In methoxy acrylic ester compounds；

Group (2)：

Selected from (b-2-1) simeconazoles (Simeconazole),

(b-2-2) Tebuconazole (Tebuconazole),

(b-2-3) RH-7592 (Fenbuconazole),

(b-2-4) hexaconazole (Hexaconazole),

(b-2-5) acid amides azoles (Imibenconazole),

(b-2-6) triazolone (Triadimefon),

(b-2-7) fluorine ether azoles (Tetraconazole),

(b-2-8) prothioconazoles (Prothioconazole),

(b-2-9) triticonazole (Triticonazole),

(b-2-10) oxole bacterium (Epoxiconazole),

(b-2-11) cycltebuconazole (Ipconazole),

(b-2-12) the azoles bacterium (Metconazole) of ring penta,

(b-2-13) propiconazole (Propiconazole),

(b-2-14) cyproconazole (Cyproconazole),

(b-2-15) Difenoconazoles (Difenoconazole),

(b-2-16) olefin conversion (Diniconazole),

(b-2-17) Fluquinconazole (Fluquinconazole),

(b-2-18) Flusilazole (Flusilazole),

(b-2-19) penconazole (Penconazole),

(b-2-20) bromuconazole (Bromuconazole),

(b-2-21) triadimenol (Triadimenol),

(b-2-22) Flutriafol (Flutriafol),

(b-2-23) nitrile bacterium azoles (Myclobutanil),

(b-2-24) etaconazole (Etaconazole) and

(b-2-25) Bitertanol (Bitertanol)

In triazole class compounds；

Group (3)：

Selected from (b-3-1) Evil oxpoconazole fumarates (Oxpoconazole fumarate),

(b-3-2) fluorine bacterium azoles (Triflumizole),

(b-3-3) IMAZALIL (Imazalil),

(b-3-4) IMAZALIL-S (Imazalil-S),

(b-3-5) Prochloraz (Prochloraz),

(b-3-6) pefurazoate (Pefurazoate) and

(b-3-7) azoles bacterium piperazine (Triazoxide)

In glyoxaline compound；

Group (4)：

Selected from (b-4-1) pyrrole metsulfovax (Penthiopyrad),

(b-4-2) flutolanil (Flutolanil),

(b-4-3) furan pyrazoles clever (Furametpyr),

(b-4-4) Boscalid (Boscalid),

(b-4-5) fenhexamid (Fenhexamid),

(b-4-6) cyflufenamid (Cyflufenamid),

(b-4-7) tecloftalam (Tecloftalam),

(b-4-8) mandipropamid (Mandipropamid),

(b-4-9) Bixafen,

(b-4-10) carboxin (Carboxin),

(b-4-11) oxycarboxin (Oxycarboxin),

(b-4-12) the third oxygen mebenil (Mepronil),

(b-4-13) Silthiopham (Silthiofam),

(b-4-14) thifluzamide (Thifluzamide),

(b-4-15) fluorine biphenyl bacterium (Flumetover),

(b-4-16) Guardian (Ethaboxam),

(b-4-17) zoxamide (Zoxamide),

(b-4-18) tiadinil (Tiadinil),

(b-4-19) isotianil (Isotianil),

(b-4-20) double chlorine zarilamid (Diclocymet),

(b-4-21) zarilamid (Fenoxanil),

(b-4-22) fluopicolide (Fluopicolide),

(b-4-23) fluopyram (Fluopyram),

(b-4-24) carpropamide (Carpropamid),

(b-4-25) Tolfenpyrad (Tolfenpyrad),

(b-4-26) N- [2- (1,3- dimethylbutyl) phenyl] fluoro- 1, the 3- dimethyl -1H- pyrroles of -5- Azoles -4- formamides,

(b-4-27) N- { 2- [1,1 '-bis- (cyclopropyl) -2- bases] phenyl } -3- (difluoromethyl) -1- first Base -1H- pyrazole-4-carboxamides,

(b-4-28) 3- (difluoromethyl)-N- (9- isopropyls -1,2,3,4- tetrahydrochysenes-Isosorbide-5-Nitrae-methanonaphthalene - 5- yls) -1- methyl isophthalic acid H- pyrazole-4-carboxamides,

(b-4-29) 3- (difluoromethyl)-N- [4 '-(3,3- dimethyl butine -1- bases) biphenyl -2- Base] -1- methyl isophthalic acid H- pyrazole-4-carboxamides,

(b-4-30) [4 '-(3- methoxyl group -3- methyl butyne -1- bases) joins 3- (difluoromethyl)-N- Benzene -2- bases] -1- methyl isophthalic acid H- pyrazole-4-carboxamides and

(b-4-31) 3- (difluoromethyl) -1- methyl-N- [1,2,3,4- tetrahydrochysene -9- (1- methyl second Base)-Isosorbide-5-Nitrae-methanonaphthalene -5- bases] -1H- pyrazole-4-carboxamides

In Carbox amide；

Group (5)：

Selected from (b-5-1) metalaxyl (Metalaxyl),

(b-5-2) metalaxyl-M (Metalaxyl-M),

(b-5-3) M 9834 (Benalaxyl),

(b-5-4) M 9834-M (Benalaxyl-M：Kiralaxyl) and

(b-5-5) furalaxyl-M (Furalaxyl-M)

In acylalaninies (acylalanine) class compound；

Group (6)：

Selected from (b-6-1) benzene metsulfovax (Benthiavalicarb-isopropyl) and

(b-6-2) iprovalicarb (Iprovalicarb)

In valyl aminated compounds；

Group (7)：

Selected from (b-7-1) cyazofamid (Cyazofamid),

(b-7-2) amisulbrom (Amisulbrom) and

(b-7-3) flusulfamide (Flusulfamide)

In sulfamide compound；

Group (8)：

Selected from (b-8-1) tolyfluanid (Tolylfluanid) and

(b-8-2) Euparen (Dichlofluanid)

In sulfinylamines compound；

Group (9)：

Selected from (b-9-1) hundred tie up clever (Propamocarb),

(b-9-2) the hundred clever hydrochlorides (Propamocarb hydrochloride) of dimension,

(b-9-3) diethofencarb (Diethofencarb) and

(b-9-4) Bi Li benzene card cloth (Pyribencarb)

In carbamate compound；

Group (10)：

Selected from (b-10-1) Mancozeb (Mancozeb) (Mancozeb),

(b-10-2) maneb (Maneb),

(b-10-3) propineb (Propineb),

(b-10-4) zineb (Zineb),

(b-10-5) Carbatene (Metiram),

(b-10-6) ziram (Ziram),

(b-10-7) thiuram (Thiuram) and

(b-10-8) polycarbamate (Polycarbamate)

In dithio amino formate compounds；

Group (11)：

Selected from (b-11-1) isopropyl fixed (Iprodione),

(b-11-2) procymidone (Procymidone),

(b-11-3) captan (Captan),

(b-11-4) vinclozolin (Vinclozolin),

(b-11-5) chlozolinate (Chlozolinate) and

(b-11-6) folpet (Folpet)

In dicarboximide class compound；

Group (12)：

Selected from the octyl benzene sulfonate (Iminoctadine-trialbesilate) of (b-12-1) biguanides three,

(b-12-2) iminoctadine triacetate (Iminoctadine-triacetate),

(b-12-3) Guanoctine (Guazatine) and

(b-12-4) dodine (Dodine)

In guanidine compound；

Group (13)：

Selected from (b-13-1) mepanipyrim (Mepanipyrim),

(b-13-2) fenarimol (Fenarimol),

(b-13-3) ferimzone (Ferimzone),

(b-13-4) cyprodinil (Cyprodinil),

(b-13-5) dimethyl mepanipyrim (Pyrimethanil),

(b-13-6) nuarimol (Nuarimol),

(b-13-7) Milcurb (Dimethirimol),

(b-13-8) the phonetic bacterium of sulphur clever (Bupirimate) and

(b-13-9) fluorine mepanipyrim (Diflumetorim)

In pyrimidines；

Group (14)：

Selected from (b-14-1) dimethomorph (Dimethomorph),

(b-14-2) butadiene morpholine (Fenpropimorph),

(b-14-3) tridemorph (Tridemorph),

(b-14-4) dodemorfe (Dodemorph) and

(b-14-5) flumorph (Flumorph)

In morpholine kind compound；

Group (15)：

Selected from (b-15-1) thiophanate (Thiophanate),

(b-15-2) thiophanate methyl (Thiophanate-methyl),

(b-15-3) benomyl (Benomyl),

(b-15-4) carbendazim (Carbendazim),

(b-15-5) Apl-Luster (Thiabendazole) and

(b-15-6) furidazol (Fuberidazole)

In benzimidazoles compound；

Group (16)：

Selected from (b-16-1) Fu Evil bacterium (Fludioxonil),

(b-16-2) fluoromide (Fluoroimide) and

(b-16-3) fenpiclonil (Fenpiclonil)

In azoles；

Group (17)：

Selected from (b-17-1) fosetyl (Fosetyl-alminium),

(b-17-2) Hinosan (Edifenphos：EDDP)、

(b-17-3) tolelofos-methyl (Tolclofos-methyl),

(b-17-4) different rice blast net (Iprobenfos：IBP) and

(b-17-5) Ppyrazophos (Pyrazophos)

In organophosphorus compound；

Group (18)：

Selected from (b-18-1) Kocide SD (Copper hydroxide),

(b-18-2) copper (Copper),

(b-18-3) basic copper chloride (Copper oxychloride),

(b-18-4) basic copper sulfate (Copper sulfate (tribasic)),

(b-18-5) copper 8-hydroxyquinolinate (Oxine-copper),

(b-18-6) cupric sulfate pentahydrate (Copper sulfate pentahydrate),

(b-18-7) anhydrous cupric sulfate (Copper sulfate),

(b-18-8) nonyl benzene copper phenolsulfonate (Copper nonylphenolsulfonate) and

(b-18-9) DBSA bis ethylene diamine copper complex salt (Copper dodecylbenzene sulfate·bis(ethylenediamine)complex：DBEDC)

In copper class compound；

Group (19)：

Selected from (b-19-1) kasugarnycin (Kasugamycin hydrochloride hydrate),

(b-19-2) valida (Validamycin),

(b-19-3) polyoxin A~N (Polyoxins A~N),

(b-19-4) blasticidin-S S benzylaminos benzene sulfonate (Blastcidin-S benzylaminobenzenesulfonate salt)、

(b-19-5) streptomysin (Streptomycin),

(b-19-6) natamycin (Natamycin),

(b-19-7) midolthromycin (Mildiomycin) and

(b-19-8) terramycin (Oxytetracycline)

In antibiotic；

Group (20)：

Selected from (b-20-1) Bravo (Chlorothalonil：TPN)、

(b-20-2) phthalide (Phthalide) and

(b-20-3) pentachloronitrobenzene (Quintozene)

In organochlorine class compound；

Group (21)：

Selected from the chloro- 7- of (b-21-1) 5- (4- methyl piperidine -1- bases) -6- (2,4,6- trifluorophenyl) [1, 2,4] triazol [1,5-a] pyrimidine,

(b-21-2) the chloro- N- of 5- [(1S) -2,2,2- tri- fluoro- 1- Methylethyls] -6- (2,4,6- trifluoros Phenyl) [1,2,4] triazol [1,5-a] pyrimidine,

(b-21-3) the chloro- N- of 5- [(1R) -1,2- dimethyl propyls] -6- (2,4,6- trifluorophenyl) [1, 2,4] triazol [1,5-a] pyrimidine,

(b-21-4) 5- (methoxy) -6- octyl groups [1,2,4] triazol [1,5-a] pyrimidine -7- amine and

(b-21-5) 5- ethyls -6- octyl groups [1,2,4] triazol [1,5-a] pyrimidine -7- amine

In triazolopyrimidines；

Group (22)：

Selected from (b-22-1) table metrafenone (Metrafenone) and

(b-22-2) 3- (2,3,4- trimethoxy -6- methyl benzoyls) chloro- 2- methoxyl groups of -5- - 4- picolines

In benzoyl compound；

Group (23)：

Selected from (b-23-1) isopropyl ((1S) -2- methyl isophthalic acids-{ [(4- methyl benzoyls) amino] methyl } Propyl group) carbamate,

(b-23-2) isopropyl ((1S) -2,2- dimethyl -1- { [(4- methyl benzoyls) amino] methyl } Propyl group) carbamate,

(b-23-3) isopropyl ((1S) -1- { [(1- benzofuran -2- bases carbonyl) amino] methyl } -2- first Base propyl group) carbamate,

(b-23-4) 2,2,2- trifluoroethyls ((1S) -2- methyl isophthalic acids-{ [(4- methyl benzoyls) amino] Methyl } propyl group) carbamate,

(b-23-5) 2,2,2- trifluoroethyls ((1S) -2,2- dimethyl -1- { [(4- methyl benzoyls) ammonia Base] methyl } propyl group) carbamate,

(b-23-6) 2,2,2- trifluoroethyls ((1S) -1- { [(1- benzofuran -2- bases carbonyl) amino] first Base } -2- methyl-propyls) carbamate,

(b-23-7) 2,2,2- trifluoroethyls { (1S) -1- methyl -2- [(4- methyl benzoyls) amino] second Base } carbamate,

(b-23-8) benzyl ((1S) -2- methyl isophthalic acids-{ [(4- methyl benzoyls) amino] methyl } propyl group) ammonia Carbamate and

(b-23-9) isopropyl ((1R) -2,2,2- tri- fluoro- 1- { [(4- methyl benzoyls) amino] methyl } Ethyl) carbamate

In ethylenediamines compound；

Group (24)：

Selected from (b-24-1) 3- [5- (4- chlorphenyls) -2,3- dimethyl isoxazole alkane -3- bases] pyridine,

(b-24-2) 3- [2,3- dimethyl -5- (4- aminomethyl phenyl) isoxazole alkyl -3- bases] pyridine and

(b-24-3) 3- [2- isopropyl -3- methyl -5- (4- chlorphenyl) isoxazole alkyl -3- bases] pyridine

In isoxazole alkyl compound；

Group (25)：

Selected from (b-25-1) quinoxyfen (Quinoxyfen),

(b-25-2) [fluoro- 2, the 3- dimethyl quinolines -4- bases of 6- (1,1- dimethyl ethyl) -8-] acetic acid Ester and

(b-25-3) [fluoro- 2, the 3- dimethyl quinolines -4- bases of 6- (1,1- dimethyl ethyl) -8-] methoxyl group Acetic acid esters

In quinolines；

Group (26)：

Selected from (b-26-1) (2Z)-{ [2- fluoro- 5- (trifluoromethyl) phenyl] sulphur } [3- (2- methoxybenzenes Base) -1,3-thiazoles alkane -2- subunits] acetonitrile and

(b-26-2) (2Z)-{ [2- fluoro- 5- (trifluoromethyl) phenyl] sulphur } [3- (2- aminomethyl phenyls) -1, 3- thiazolidin-2-ylidenes] acetonitrile

In thiazolidine compounds；

Group (27)：

Selected from (b-27-1) 1- [(2- acrylic sulfenyl) carbonyl] -2- (1- Methylethyls) -4- (2- methyl Phenyl) -5- amino -1H- pyrazoles -3- ketone,

(b-27-2) 1- [(ethylsulfanyl) carbonyl] -2- (1- Methylethyls) -4- (2- aminomethyl phenyls) - 5- amino -1H- pyrazoles -3- ketone and

(b-27-3) 1- [(ethylsulfanyl) carbonyl] -2- (1- Methylethyls) -4- (2,6- dichlorophenyl) - 5- amino -1H- pyrazoles -3- ketone

In pyrazoline ketone compounds；And

Group (28)：

Selected from (b-28-1) hydroxyisoxazole (Hydroxyisoxazol：Hymexazol)、

(b-28-2) fluazinam (Fluazinam),

(b-28-3) diclomezine (Diclomezine),

(b-28-4) tricyclazole (Tricyclazole),

(b-28-5) cymoxanil (Cymoxanil),

(b-28-6) azolactones bacterium (Famoxadone),

(b-28-7) Fenamidone (Fenamidone),

(b-28-8) chloropicrin (Chloropicrin),

(b-28-9) thiadiazine (Thiadiazine：Milneb)、

(b-28-10) the third oxygen quinoline (Proquinazid),

(b-28-11) Loazolamines (Spiroxamine),

(b-28-12) fenpropidin (Fenpropidin),

(b-28-13) Delan (Dithianon),

(b-28-14) Pencycuron (Pencycuron),

(b-28-15) Isoprothiolane (Isoprothiolane),

(b-28-16) probenazole (Probenazole),

(b-28-17) resveratrol (Resveratrol),

(b-28-18) triforine (Triforine),

(b-28-19) thiadiazoles element-S- methyl (Acibenzolar-S-methyl),

(b-28-20) pyroquilon (Pyroquilon),

(b-28-21) dinocap (Dinocap),

(b-28-22) dimethylamino aminodithioformic acid nickel (Nickel bis (dimethyldithiocarbamate))、

(b-28-23) kobam (Echlomezol：Etridiazole)、

(b-28-24) Evil frosts clever (Oxadixyl),

(b-28-25) ambam (Amobam),

(b-28-26) pyrifenox (Pyrifenox),

(b-28-27) oxolinic acide (Oxolinic acid),

(b-28-28) phosphorous acid (Phosphorous acid),

(b-28-29) dazomet (Dazomet),

(b-28-30) methyl-isorhodanate (Methyl-isothiocyanate),

(b-28-31) methasulfocarb (Methasulfocarb),

(b-28-32) 1,3- dichloropropylenes,

(b-28-33) Carbam NCS (Carbam：Metam)、

(b-28-34) iodomethane (Iodomethane),

(b-28-35) sulphur (Sulfur),

(b-28-36) lime sulfur (Calcium polysulfide),

(b-28-37) fentin (Fentin),

(b-28-38) hypochlorous acid sodium salt (Sodium hypochlorite),

(b-28-39) chinomethionat (Chinomethionat),

(b-28-40) chloroneb (Chloroneb),

(b-28-41) anilazine (Anilazine),

(b-28-42) isopropyl disappear (Nitrothal-isopropyl),

(b-28-43) plant clothing ester (Fenitropan),

(b-28-44) botran (Dicloran) and

(b-28-45) benthiozole (benthiazole) (2- (thiocyanatomethylthio) benzothiazole：TCMTB)

In other sterilization fungicidal agents.

It should be noted that in compound (I), when m is 0, Ym represents hydrogen atom, and when n is 0, Xn represents hydrogen atom.

The plant disease control composition of the present invention is to the various plants pathogen including drug-resistant bacterium (for example, rice Rice blast (Pyricularia oryzae), tomato, the gray mold (Botrytis cinerea) etc. of cucumber and Kidney bean) have Multiple diseases are composed, and show the excellent preventive effect (preventive effect of collaboration) that can not be expected by separate constituent.In addition, even if For also showing that the resistant bacterium of existing medicine high plant disease control effect, and do not find to produce poisoning to plant.

Embodiment

Each term used in compound (I) in claims hereof and specification, as long as no being particularly limited to, Then according to definition usually used in chemical field and WO2005/070917 publications, Japanese Unexamined Patent Publication 2007-1944 public affairs Definition described in report, WO2007/011022 publications and Japanese Unexamined Patent Publication 2007-217353 publications.

In the compound (I) of the present invention, " C₁~C₆Alkyl " or " C₁~C₆The C of alkane imino group "₁~C₆Moieties example Such as can be methyl, ethyl, propyl group, isopropyl, butyl, isobutyl group, sec-butyl, the tert-butyl group, amyl group, isopentyl, 2- methyl fourths Base, neopentyl, 1- ethyl propyls, hexyl, 4- methyl amyls, 3- methyl amyls, 2- methyl amyls, 1- methyl amyls, 3, 3- dimethylbutyls, 2,2- dimethylbutyls, 1,1- dimethylbutyls, 1,2- dimethylbutyls, 1,3- dimethyl butyrates The straight or branched alkyl of the carbon numbers 1 to 6 such as base, 2,3- dimethylbutyls, 2- ethyl-butyls, preferably carbon number Straight or branched alkyl (the C of 1 to 5₁~C₅Alkyl), the more preferably straight or branched alkyl (C for carbon number 1 to 4₁~ C₄Alkyl), the more preferably straight or branched alkyl (C of carbon number 1 to 3₁~C₃Alkyl), particularly preferably methyl, Ethyl or propyl group, most preferably methyl or ethyl.

In the compound (I) of the present invention, " C₂~C₆Alkenyl " can be any in straight or branched, can contain more than 1 Any number double bond, such as can be vinyl, 1- propylene -1- bases, pi-allyl, isopropenyl, 1- butene-1s - Base, 2- butene-1s-base, 3- butene-1s-base, 2- methyl -2- propylene -1- bases, 1- methyl -2- propylene - 1- bases, 1- amylene -1- bases, 2- amylene -1- bases, 3- amylene -1- bases, 4- amylene -1- bases, 3- methyl - 2- butene-1s-base, 3- methyl -3- butene-1s-base, 1- hexene -1- bases, 2- hexene -1- bases, 3- oneself Alkene -1- bases, 4- hexene -1- bases, 5- hexene -1- bases or 4- methyl -3- amylene -1- bases, preferably ethene Base, pi-allyl, isopropenyl or 1- butene-1s-base, it is more preferably pi-allyl or isopropenyl.

In the compound (I) of the present invention, " C₂~C₆Alkynyl " can be any in straight or branched, contain more than 1 Three keys of any number, for example, can be acetenyl, 1- propine -1- bases, 2- propine -1- bases, 1- butine -1- bases, 3- butine -1- bases, 1- methyl -2- propine -1- bases, 1- pentyne -1- bases, 4- pentyne -1- bases, 1- oneself Alkynes -1- bases or 5- hexin -1- bases, preferably acetenyl or 1- propine -1- bases.

In the compound (I) of the present invention, " aryl " for example can be phenyl, 1- naphthyls, 2- naphthyls, anthryl, phenanthryl, acenaphthene The C such as base₆~C₁₆The aromatic hydrocarbyl of (carbon number 6~16), preferably phenyl, 1- naphthyls or 2- naphthyls, more preferably for Phenyl.

In the compound (I) of the present invention, " heteroaryl " is any in being mononuclear type or being how ring-like, can contain 1 or 2 It is identical or different into ring hetero atom more than individual, the heteroatomic species is not particularly limited, such as can be nitrogen-atoms, Oxygen atom or sulphur atom.Heteroaryl for example can be furyl, thienyl, pyrrole radicals, oxazolyl, isoxazolyls, Er Qing Yi Evil Oxazolyl, thiazolyl, isothiazolyl, imidazole radicals, pyrazolyl, oxadiazolyls, thiadiazolyl group, triazolyl, tetrazole radical, pyridine radicals, nitrogen It is miscellaneousBase (azepinyl group), oxygen azepineThe monocyclic heteroaryl of 5 to 7 yuan of base etc., in addition, forming the more of heteroaryl Ring-like heteroaryl can be benzofuranyl, isobenzofuran-base, benzothienyl, indyl, isoindolyl, indazolyl, benzene And oxazolyl, benzoisoxazole base, benzothiazolyl, benzisothia oxazolyl, Ben Bing oxadiazolyl, diazosulfide base, benzo Triazolyl, quinolyl, isoquinolyl, cinnolines base, quinazolyl, quinoxalinyl, phthalazinyl, naphthyridines base, purine Base, pteridyl (Pteridinyl), carbazyl, carboline base, acridinyl, 2- acridinyls, 3- acridinyls, 4- acridinyls, 9- The how ring-like heteroaryl of 8 to 14 yuan of acridinyl, phenoxazine group, phenothiazinyl, phenazinyl etc., preferably furyl, thienyl, Evil Oxazolyl, pyridine radicals, benzofuranyl or isobenzofuran-base are more preferably furyl, thienyl, oxazolyls or pyridine radicals, special You Xuanwei not furyl or thienyl.

In the compound (I) of the present invention, " aralkyl " refers to above-mentioned " C₁~C₆The hydrogen atom of more than 1 or 2 of alkyl " The group that (be preferably 1~3 hydrogen atom, more preferably 1~2 hydrogen atom) is substituted by above-mentioned " aryl ", for example, can be benzyl, 1- naphthyl methyls, 2- naphthyl methyls, anthrylmethyl, phenanthryl methyl, acenaphthenyl methyl, diphenyl methyl, 1- phenethyls, 2- benzene Ethyl, 1- (1- naphthyls) ethyl, 1- (2- naphthyls) ethyl, 2- (1- naphthyls) ethyl, 2- (2- naphthyls) ethyl, 3- Phenyl propyl, 3- (1- naphthyls) propyl group, 3- (2- naphthyls) propyl group, 4- phenyl butyls, 4- (1- naphthyls) butyl, 4- (2- naphthyls) butyl, 5- phenylpentyls, 5- (1- naphthyls) amyl group, 5- (2- naphthyls) amyl group, 6- Phenylhexyls, 6- (1- naphthyls) hexyl or 6- (2- naphthyls) hexyl, preferably benzyl, diphenyl methyl, 1- phenethyls or 2- phenethyls, compared with Preferably benzyl.

In the compound (I) of the present invention, " C₃~C₁₀Cycloalkyl ring " is, for example, that ethylidene, three are bonded on 1 carbon atom 2~9 alkylidenes of the carbon numbers such as methylene, tetramethylene, pentamethylene, hexa-methylene, heptamethylene, eight methylene and shape Into cyclic hydrocarbon group, be preferably bonded trimethylene, tetramethylene or pentamethylene and formed cyclic hydrocarbon group (cyclobutyl ring, Cyclopenta ring or cyclohexyl ring), the cyclic hydrocarbon group (cyclohexyl ring) more preferably formed for bonding pentamethylene.

In the compound (I) of the present invention, " halogen atom " is fluorine atom, chlorine atom, bromine atoms or iodine atom, and preferably fluorine is former Son, chlorine atom or bromine atoms, are more preferably fluorine atom or chlorine atom, most preferably fluorine atom.

In the compound (I) of the present invention, " C₁~C₆Alkoxy " be, for example, methoxyl group, ethyoxyl, propoxyl group, isopropoxy, Butoxy, isobutoxy, sec-butoxy, tert-butoxy, amoxy, isoamoxy, 2- methylbutoxy groups, neopentyl oxygen, 1- Ethylpropoxy, hexyloxy, (4- methyl amyls) epoxide, (3- methyl amyls) epoxide, (2- methyl amyls) epoxide, (1- Methyl amyl) epoxide, 3,3- dimethyl butyrates epoxide, 2,2- dimethyl butyrates epoxide, 1,1- dimethyl butyrates epoxide, 1,2- diformazans The carbon numbers such as base butoxy, 1,3- dimethyl butyrates epoxide, 2,3- dimethyl butyrates epoxide, 2- ethyl-butoxies 1 to 6 are straight Straight or branched alkoxyl (the C of chain or branched alkoxy, preferably carbon number 1 to 4₁~C₄Alkoxy), it is more preferably first Epoxide, ethyoxyl or isopropoxy, more preferably methoxy or ethoxy, most preferably methoxyl group.

In the compound (I) of the present invention, " C₁~C₆Alkylthio group " be, for example, methyl mercapto, ethylmercapto group, rosickyite base, isopropyisulfanyl, The carbon numbers 1 to 6 such as butylthio, isopentylthio, new penta sulfenyl, 3,3- dimethylbutyls sulfenyl, 2- ethyl-butyl sulfenyls Straight or branched alkylthio group, preferably carbon number 1 to 4 straight or branched alkylthio group, be more preferably methyl mercapto.

In the compound (I) of the present invention, " acyl group " can be for example formoxyl, be bonded with above-mentioned " C₁~C₆The carbonyl of alkyl " Base (C₂~C₇Alkyl-carbonyl), be bonded with above-mentioned " C₂~C₆Carbonyl (the C of alkenyl "₃~C₇Alkenyl carbonyl), be bonded with it is above-mentioned The carbonyl (" aryl carbonyl ") of " aryl ", it is bonded with above-mentioned " C₁~C₆Carbonyl (the C of alkoxy "₂~C₇Alkoxy carbonyl) or key Conjunction has above-mentioned " C₁~C₆Carbonyl (the C of alkylthio group "₂~C₇Alkyl sulfenyl carbonyl), preferably formoxyl, C₂~C₅Alkyl-carbonyl, C₃ ~C₅Alkenyl carbonyl, benzoyl, naphthoyl, C₂~C₅Alkoxy carbonyl or C₂~C₅Alkyl sulfenyl carbonyl, more preferably for Formoxyl, C₂~C₅Alkyl-carbonyl, benzoyl or C₂~C₅Alkoxy carbonyl, particularly preferably acetyl group, methoxycarbonyl, Ethoxy carbonyl or benzoyl, most preferably acetyl group.

In the compound (I) of the present invention, " C₂~C₇Alkoxy carbonyl " for example can be methoxycarbonyl, ethoxy carbonyl, The alkoxy carbonyl of the carbon numbers such as propoxycarbonyl 2 to 7, its alkoxy portion can be straight or branched, preferably carbon The alkoxy carbonyl of atomicity 2 to 4, it is more preferably methoxycarbonyl.

In the compound (I) of the present invention, " the C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkyl ", remove Above-mentioned " C₁~C₆Outside alkyl ", such as trifluoromethyl, trichloromethyl, difluoromethyl, dichloromethyl, dibromo first can also be Base, methyl fluoride, chloromethyl, bromomethyl, iodomethyl, 2,2,2- trichloroethyls, 2,2,2- trifluoroethyls, 2- bromoethyls, 2- Chloroethyl, 2- fluoro ethyls, 3- chloropropyls, 3,3,3- trifluoro propyls, 4- fluorine butyl, the fluoro- 2- methyl-propyls of 3-, 3,3, The fluoro- 2- methyl-propyls of 3- tri-, 6,6,6- trichlorine hexyls etc. are substituted by identical or different 1~3 above-mentioned " halogen atom " Above-mentioned " C₁~C₆Alkyl ", the above-mentioned " C that can be preferably substituted by identical or different 1~3 above-mentioned " halogen atom "₁~C₄Alkane Base ", the more preferably above-mentioned " C for that can be substituted by identical or different 1~3 " fluorine atom or chlorine atom "₁~C₃Alkyl ", enter one Step is preferably methyl, ethyl, propyl group, chloromethyl or trifluoromethyl, particularly preferably methyl, ethyl or trifluoromethyl.

In the compound (I) of the present invention, " N- hydroxyls C₁~C₆Alkane imino group, the N- hydroxyls C₁~C₆Alkane imido The hydrogen atom of hydroxyl can be chosen free C in base₁~C₆Alkyl, C₂~C₆Alkenyl, C₂~C₆Alkynyl, aralkyl, aryl and heteroaryl Substituent substitution in the group of base composition ", such as can be oxyimino methyl, N- hydroxyl ethanes imino group, N- hydroxyls The N- hydroxyl alkane imino groups of the carbon numbers 1~6 such as propane imino group, N- hydroxybutane imino groups, in addition, may be used also To be the hydroxyl by above-mentioned " C₁~C₆Alkyl ", above-mentioned " C₂~C₆Alkenyl ", above-mentioned " C₂~C₆Alkynyl ", above-mentioned " aralkyl ", The group of above-mentioned " aryl " or above-mentioned " heteroaryl " substitution, such as can be methoxyimino methyl, N- Ethyl Methyl Ethers Asia Amino, N- Ethoxyethanes imino group, N- butoxy ethane imino group, N- allyloxy ethane imino group, N- propynyloxies Base ethane imino group, N- benzyloxy ethane imino group, N- phenoxy group ethane imino group, N- pyridine radicals epoxide ethane imino group, The hydrogen of N- methoxy propanes imino group, N- methyl butyl ethers imino group or N- methoxyhexane imino groups, preferably hydroxyl is former Son can be chosen free C₁~C₆Substituent substitution, carbon number 1~4 N- hydroxyl alkane in the group of alkyl and phenyl composition Hydrocarbon imino, it is more preferably oxyimino methyl, N- hydroxyl ethanes imino group, methoxyimino methyl, N- methoxyl groups Ethane imino group or N- Ethoxyethane imino groups, particularly preferably methoxyimino methyl or N- Ethyl Methyl Ether imido Base.

In the compound (I) of the present invention, R¹Deng " free halogen, C can be chosen₁~C₆Alkoxy, C₁~C₆Alkylthio group and The C of identical or different 1~3 substituent substitution in the group of phenoxy group composition₁~C₆Alkyl ", except it is above-mentioned " can be identical Or the C of different 1~3 halogen atom substitutions₁~C₆Outside alkyl ", such as methoxy, ethoxyl methyl, second can also be Epoxide ethyl, propoxy methyl etc. are by 1~3 identical or different above-mentioned " C₁~C₆Above-mentioned " the C of alkoxy " substitution₁~C₆Alkane Base ", methylsulfanylmethyl, ethylsulfanyl methyl, ethylsulfanyl ethyl etc. are by 1~3 identical or different above-mentioned " C₁~C₆Alkane Above-mentioned " the C of sulfenyl " substitution₁~C₆Above-mentioned " the C that alkyl " or phenoxymethyl, Phenoxyethyl etc. are substituted by phenoxy group₁~C₆ Alkyl ", and then, in addition to 2- methoxyl group -1- chloroethyls, the bromo- 2- methoxy-propyls of 3- phenoxy groups -2-, 3- benzene oxygen Bromo- 2- methylsulfanies propyl group of base -2- etc., selected freely above-mentioned halogen atom, above-mentioned C₁~C₆Alkoxy, above-mentioned C₁~C₆Alkane Above-mentioned " the C of 2~3 kinds of substituents substitution in the group of sulfenyl and phenoxy group composition₁~C₆Alkyl ", preferably methyl, ethyl, third Base, methoxy, ethoxyl methyl, phenoxymethyl or methylsulfanylmethyl, it is more preferably methyl or ethyl.

In the compound (I) of the present invention, X's etc. " can be chosen free halogen, C₁~C₆Alkoxy, hydroxyl, C₂~C₇Alkane The C of identical or different 1~3 substituent substitution in Epoxide carbonyl and the group of phenoxy group composition₁~C₆Alkyl ", except above-mentioned " the C that can be substituted by 1~3 identical or different halogen atom₁~C₆Outside alkyl ", such as methoxy, ethoxy can also be Ylmethyl, ethoxyethyl group, propoxy methyl etc. are by 1~3 identical or different above-mentioned " C₁~C₆Alkoxy " substitutes above-mentioned “C₁~C₆Above-mentioned " the C that alkyl ", hydroxymethyl, 2- hydroxyethyls, 3- hydroxypropyls etc. are substituted by 1~3 hydroxyl₁~C₆Alkane Base ", Methoxycarbonylmethyl, ethoxy carbonyl methyl, 2- (methoxycarbonyl) ethyl etc. are by identical or different 1~3 State " C₂~C₇Above-mentioned " the C of alkoxy carbonyl " substitution₁~C₆Alkyl " or phenoxymethyl, Phenoxyethyl etc. are taken by phenoxy group Above-mentioned " the C in generation₁~C₆Alkyl ", and then, in addition to 2- methoxyl group -1- chloroethyls, 2- hydroxyl -1- chloroethyls, 3- benzene Bromo- 2- methoxycarbonylpropyls of epoxide -2- etc., selected freely above-mentioned halogen atom, above-mentioned C₁~C₆It is alkoxy, hydroxyl, above-mentioned C₂~C₇Above-mentioned " the C of 2~3 kinds of substituents substitution in the group of alkoxy carbonyl and phenoxy group composition₁~C₆Alkyl ", it is preferably Methyl, ethyl, propyl group, methoxy, ethoxyl methyl, phenoxymethyl, methylsulfanylmethyl, Methoxycarbonylmethyl or Ethoxy carbonyl methyl, it is more preferably methyl or ethyl.

In the compound (I) of the present invention, X's etc. " can be chosen free halogen, C₁~C₆Alkoxy, C₂~C₇Alkoxy carbonyl The C of identical or different 1~3 substituent substitution in the group of base and phenoxy group composition₂~C₆Alkenyl ", except above-mentioned " C₂ ~C₆Outside alkenyl ", it can also be such as 3- chlorallyls, the bromo- 2- cyclobutenyls of 4- by identical or different 1~3 Above-mentioned " the C of individual halogen atom substitution₂~C₆The quilts such as alkenyl ", 3- methoxyl group -2- acrylic, 4- ethyoxyl -3- cyclobutenyls 1~3 identical or different above-mentioned " C₁~C₆Above-mentioned " the C of alkoxy " substitution₂~C₆Alkenyl ", Methoxycarbonylvinyl, 3- (ethoxy carbonyl) -2- acrylic, 4- (methoxycarbonyl) -2- cyclobutenyls etc. are by identical or different 1~3 State " C₂~C₇Above-mentioned " the C of alkoxy carbonyl " substitution₂~C₆Alkenyl " or 3- phenoxy group -2- cyclobutenyls etc. are taken by phenoxy group Above-mentioned " the C in generation₂~C₆Alkenyl ", and then, in addition to the chloro- 2- cyclobutenyls of 4- methoxyl groups -3-, 4- methoxycarbonyls - The chloro- 2- cyclobutenyls of 3-, the chloro- 2- cyclobutenyls of 4- phenoxy groups -3- etc., selected freely above-mentioned halogen atom, above-mentioned C₁~C₆Alkane Epoxide, above-mentioned C₂~C₇Above-mentioned " the C of 2~3 kinds of substituents substitution in the group of alkoxy carbonyl and phenoxy group composition₂~C₆Alkene Base ", preferably vinyl, pi-allyl, isopropenyl, 1- butene-1s-base, 3- chlorallyls, the bromo- 2- cyclobutenyls of 4-, Methoxycarbonylvinyl or 4- methoxycarbonyl cyclobutenyls, it is more preferably pi-allyl or isopropenyl.

In the compound (I) of the present invention, X's etc. " can be chosen free halogen, C₁~C₆What alkoxy and phenoxy group formed The C of identical or different 1~3 substituent substitution in group₂~C₆Alkynyl ", except above-mentioned " C₂~C₆Outside alkynyl ", may be used also Be substituted such as the chloro- 2-propynyls of 3-, the bromo- 2- butynyls of 4- by 1~3 identical or different halogen atom it is upper State " C₂~C₆Alkynyl ", 3- methoxyl groups -2-propynyl, 4- ethyoxyl -3- butynyls etc. are by identical or different 1~3 Above-mentioned " C₁~C₆Above-mentioned " the C of alkoxy " substitution₂~C₆What alkynyl " or 3- phenoxy group -2- butynyls etc. were substituted by phenoxy group Above-mentioned " C₂~C₆Alkynyl ", and then, in addition to the chloro- 2- butynyls of 4- methoxyl groups -4-, the chloro- 2- of 4- phenoxy groups -4- Butynyl etc., selected freely above-mentioned halogen atom, above-mentioned C₁~C₆2~3 kinds of substituents in the group of alkoxy and phenoxy group composition take Above-mentioned " the C in generation₂~C₆Alkynyl " is preferably acetenyl, 1- propine -1- bases, the chloro- 2-propynyls of 3-, 3- methoxies The chloro- 2- butynyls of base -2-propynyl, 4- methoxyl groups -4- or the chloro- 2- butynyls of 4- phenoxy groups -4-, it is preferably Acetenyl or 1- propine -1- bases.

In the compound (I) of the present invention, X's etc. " can be by 1~2 identical or different C₁~C₆What alkyl or acyl group substituted Amino ", in addition to amino, also there is 1~2 identical or different above-mentioned " C for substitution₁~C₆Alkyl " or identical or different 1 The amino of~2 above-mentioned " acyl group ", preferably substitution have 1~2 identical or different above-mentioned " C₁~C₄Alkyl " is identical or not With 1~2 above-mentioned " acyl group " amino, be more preferably dimethylamino, diethylamino or acetylamino.

In the compound (I) of the present invention, R³And R⁴" the C formed together₁~C₆Alkylidene ", for example, being methylene (methene Base), ethylidene, propylidene, 1 to 6 straight or branched alkylidene of carbon number, preferably carbon number 1 to 4 such as isopropylidene Individual straight or branched alkylidene, particularly preferably methylene (methene base).

In the compound (I) of the present invention, R¹Deng " free halogen can be chosen, can be by 1~3 identical or different halogen The C of atom substitution₁~C₆Alkyl, C₁~C₆Alkoxy, can be by 1~2 identical or different C₁~C₆What alkyl or acyl group substituted Amino, nitro, cyano group, hydroxyl, sulfydryl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkylthio group composition Aryl ", in addition to above-mentioned " aryl ", can also be substituted by 1~6 identical or different above-mentioned halogen atom it is above-mentioned " aryl ", by 1~6 identical or different above-mentioned " C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkyl " Above-mentioned " aryl " of substitution, by 1~6 identical or different above-mentioned " C₁~C₆It is above-mentioned " aryl " of alkoxy " substitution, identical Or it is different 1~6 it is above-mentioned " can be by 1~2 identical or different C₁~C₆Alkyl, the amino of acyl group substitution " substitutes above-mentioned " aryl ", by above-mentioned " aryl " that 1~6 nitro substitutes, above-mentioned " aryl " that is substituted by 1~6 cyano group or by 1~6 hydroxyl Above-mentioned " aryl " of base substitution, above-mentioned " aryl " that is substituted by 1~6 sulfydryl or by 1~6 identical or different above-mentioned " C₁ ~C₆Above-mentioned " aryl " of alkylthio group " substitution, and then, include the above-mentioned halogen atom of selected freedom, it is above-mentioned " can be identical or different 1~3 halogen atom substitution C₁~C₆Alkyl ", above-mentioned " C₁~C₆Alkoxy ", it is above-mentioned " can be by identical or different 1~2 C₁~C₆Alkyl or the amino of acyl group substitution ", nitro, cyano group, hydroxyl, sulfydryl and above-mentioned " C₁~C₆In the group of alkylthio group " composition The substitution of 2~6 kinds of substituents above-mentioned " aryl ", preferably phenyl, 1- naphthyls, 2- naphthyls, 4- fluorophenyls, 4- chlorobenzenes Base, 3- methoxyphenyls, 3- cyano-phenyls, 2- methylsulfanylphenyls or 2- trifluoromethyls are more preferably phenyl, 4- fluorophenyls or 4- chlorphenyls.

In the compound (I) of the present invention, R¹Deng " free halogen can be chosen, can be by 1~3 identical or different halogen The C of atom substitution₁~C₆Alkyl and C₁~C₆Identical or different 1~6 substituent in the group of alkoxy composition substitutes miscellaneous Aryl ", in addition to above-mentioned " heteroaryl ", can also be for example substituted by 1~6 identical or different halogen atom it is above-mentioned " heteroaryl ", by 1~6 identical or different above-mentioned " C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkane Above-mentioned " heteroaryl " of base " substitution or by 1~6 identical or different above-mentioned " C₁~C₆Above-mentioned " the heteroaryl of alkoxy " substitution Base ", and then, in addition to selected freely above-mentioned halogen atom, above-mentioned " C₁~C₆Alkyl " and above-mentioned " C₁~C₆The group of alkoxy " composition In the substitution of 2~6 kinds of substituents above-mentioned " heteroaryl ", preferably furyl, thienyl, oxazolyls, pyridine radicals, benzofuran Base, isobenzofuran-base, 5- bromines furyl, 6- chloropyridines base, 4- trifluoromethyl pyridines base, 3- fluorine thienyl or 3- first Epoxide thienyl, it is more preferably furyl or thienyl.

In the compound (I) of the present invention, R¹Deng " free halogen can be chosen, can be by 1~3 identical or different halogen The C of atom substitution₁~C₆Alkyl, C₁~C₆Alkoxy, can be by 1~2 identical or different C₁~C₆What alkyl or acyl group substituted Amino, nitro, cyano group, hydroxyl, sulfydryl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkylthio group composition Aralkyl ", in addition to above-mentioned " aralkyl ", can also be substituted by 1~6 identical or different halogen atom it is above-mentioned " aralkyl ", by 1~6 identical or different above-mentioned " C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkane Above-mentioned " aralkyl " of base " substitution, by 1~6 identical or different above-mentioned " C₁~C₆Above-mentioned " the aralkyl of alkoxy " substitution Base ", by identical or different 1~6 is above-mentioned " can be by 1~2 identical or different C₁~C₆Alkyl or the amino of acyl group substitution " Above-mentioned " aralkyl " of substitution, by above-mentioned " aralkyl " that 1~6 nitro substitutes, the above-mentioned " aralkyl substituted by 1~6 cyano group Base ", by above-mentioned " aralkyl " that 1~6 hydroxyl substitutes, above-mentioned " aralkyl " that is substituted by 1~6 sulfydryl or by identical or not 1~6 same above-mentioned " C₁~C₆Above-mentioned " aralkyl " of alkylthio group " substitution, and then, in addition to selected freely above-mentioned halogen atom, Above-mentioned " the C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkyl ", above-mentioned " C₁~C₆Alkoxy ", it is above-mentioned " can By 1~2 identical or different C₁~C₆Alkyl or the amino of acyl group substitution ", nitro, cyano group, hydroxyl, sulfydryl and above-mentioned " C₁~ C₆Above-mentioned " aralkyl " of substituent of more than two kinds substitution in the group of alkylthio group " composition, when aralkyl has substituent, The substituent can form aralkyl aryl rings on or alkyl on either one or both substituted, preferably benzyl, Diphenyl methyl, 1- phenethyls, 2- phenethyls, 4- chlorobenzyls, 3- cyanobenzyls or 4- methylsulfany -2- phenethyls, More preferably it is benzyl.

In the compound (I) of the present invention, R¹And R²Deng " it is being formed together with the carbon atom being bonded with them, can by selected from By halogen atom, C₁~C₆Alkyl, C₁~C₆Identical or different 1~3 substituent in the group of alkoxy and phenoxy group composition takes The C in generation₃~C₁₀Cycloalkyl ring ", except above-mentioned " C₃~C₁₀Outside cycloalkyl ring ", it can also be for example by identical or different 1 Above-mentioned " the C of~3 halogen atom substitutions₃~C₁₀Cycloalkyl ring ", by 1~3 identical or different above-mentioned " C₁~C₆Alkyl " substitutes Above-mentioned " C₃~C₁₀Cycloalkyl ring ", by 1~3 identical or different above-mentioned " C₁~C₆Above-mentioned " the C of alkoxy " substitution₃~C₁₀ Cycloalkyl ring " or the above-mentioned " C substituted by 1~3 identical or different phenoxy group₃~C₁₀Cycloalkyl ring ", and then, in addition to quilt Selected from by above-mentioned halogen atom, above-mentioned " C₁~C₆Alkyl ", above-mentioned " C₁~C₆2~3 kinds in the group of alkoxy " and phenoxy group composition Above-mentioned " the C of substituent substitution₃~C₁₀Cycloalkyl ring ", preferably cyclobutyl ring, cyclopenta ring, cyclohexyl ring, 2- chlorine cyclopenta Ring, 4- methyl cyclohexanes basic ring, 3- methoxycyclohexyls basic ring or 3- phenoxy group cyclohexyl rings, are more preferably cyclohexyl ring.

In the compound (I) of the present invention, X can substitute 1~4 on the commutable optional position on isoquinolin ring, When X has 2~4 (when n is more than 2), they can be with identical or different.

In the compound (I) of the present invention, Y can substitute 1~6 on the commutable optional position on quinoline ring, work as Y In the presence of (when m is more than 2), they can be with identical or different at 2~6.

The compound (I) of the present invention can be made into the inorganic acid salt such as hydrochloride, sulfate, nitrate：Phosphate；First sulphur The sulfonate such as hydrochlorate, esilate, benzene sulfonate, tosilate；Or acetate, benzoate, oxalates, fumaric acid The salt of the organic carboxylates such as salt, salicylate etc (is preferably hydrochloride, sulfate, nitrate, mesylate, oxalates, richness Horse hydrochlorate or salicylate).

The compound (I) and its salt of the present invention can be made into solvate, and these solvates are also included in the present invention.On It is preferably hydrate to state solvate.

In the compound (I) of the present invention, also including has chiral carbon compound, in this case, the present application Also a kind of mixture of the arbitrary proportion comprising optically active body and several optically active bodies.

In the compound (I) of the present invention,

R¹And R²For：

(1a) is preferably the C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkyl can be identical or different 1~5 halogen atom substitution phenyl,

(1b) is more preferably methyl, ethyl, propyl group, trifluoromethyl, trifluoroethyl, phenyl, fluorophenyl or chlorphenyl,

R³And R⁴For：

(2a) is preferably hydrogen atom, halogen atom or C₁~C₄Alkyl,

(2b) is more preferably hydrogen atom, fluorine atom, chlorine atom, methyl or ethyl,

(2c) is more preferably hydrogen atom, fluorine atom or methyl,

Xn is：

(3a) preferably X is halogen atom；C₁~C₆Alkyl；C₂~C₆Alkynyl；Free halogen can be chosen, can be by identical or not The C of same 1~3 halogen atom substitution₁~C₆Alkyl and C₁~C₆Identical or different 1~6 in the group of alkoxy composition takes For the aryl of base substitution；Free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl and C₁~C₆The heteroaryl of identical or different 1~6 substituent substitution in the group of alkoxy composition；Cyano group；Or N- hydroxyls- C₁~C₆Alkane imino group, the N- hydroxyls-C₁~C₆The hydrogen atom of hydroxyl can be chosen free C in alkane imino group₁~C₆Alkane Substituent substitution in the group of base and phenyl composition；N is 0~2 integer,

(3b) more preferably X is halogen atom；C₁~C₄Alkyl；C₂~C₃Alkynyl；Can be chosen free fluorine atom, chlorine atom, can quilt The C of 1~3 fluorine atom substitution₁~C₂Alkyl and C₁~C₂Identical or different 1~2 substituent in the group of alkoxy composition Substituted phenyl；Furyl, thienyl, oxazolyls or pyridine radicals, the furyl, thienyl, oxazolyls or pyridine radicals can quilts Selected from by fluorine atom, chlorine atom, the C that can be substituted by 1~3 fluorine atom₁~C₂Alkyl and C₁~C₂In the group of alkoxy composition Identical or different 1~3 substituent substitution；Cyano group；Or N- hydroxyls-C₁~C₂Alkane imino group, the N- hydroxyls-C₁ ~C₂The hydrogen atom of hydroxyl can be chosen free C in alkane imino group₁~C₂Substituent substitution in the group of alkyl and phenyl composition；n For 0~2 integer,

(3c) further preferably X be fluorine atom, chlorine atom, bromine atoms, methyl, acetenyl, furyl, thienyl, cyano group, Ethyl Methyl Ether imino group, Ethoxyethane imino group or phenoxy group ethane imino group, n are 0 or 1,

Ym is：

(4a) preferably Y is fluorine atom, chlorine atom, bromine atoms or C₁~C₃Alkyl, m are 0~2,

(4b) more preferably Y is fluorine atom, chlorine atom or methyl, and m is 0 or 1,

(4c) further preferably Y is fluorine atom or methyl, and m is 0 or 1.

It is also preferable to the selection R from (1a)~(1b)¹And R², from (2a)~(2c) selection R³And R⁴, from (3a)~ Selection Xn in (3c), selection Ym and compound obtained from they are combined from (4a)~(4c), can enumerate such as followingization Compound：

Compound (A1), wherein, R¹And R²For the C that can be substituted by 1~3 identical or different halogen atom₁~C₆Alkyl or The phenyl that can be substituted by 1~5 identical or different halogen atom,

R³And R⁴For hydrogen atom, halogen atom or C₁~C₄Alkyl,

X is halogen atom；C₁~C₆Alkyl；C₂~C₆Alkynyl；Free halogen can be chosen, can be by identical or different 1~3 The C of individual halogen atom substitution₁~C₆Alkyl and C₁~C₆Identical or different 1~6 substituent substitution in the group of alkoxy composition Aryl；Free halogen, the C that can be substituted by 1~3 identical or different halogen atom can be chosen₁~C₆Alkyl and C₁~C₆Alkane The heteroaryl of identical or different 1~6 substituent substitution in the group of epoxide composition；Cyano group；Or N- hydroxyls-C₁~C₆Alkane Hydrocarbon imino, the N- hydroxyls-C₁~C₆The hydrogen atom of hydroxyl can be chosen free C in alkane imino group₁~C₆Alkyl and phenyl Substituent substitution in the group of composition, n are 0~2 integer,

Y is fluorine atom, chlorine atom, bromine atoms or C₁~C₃Alkyl, m are 0~2；

Compound (A2), wherein, R¹And R²For methyl, ethyl, propyl group, trifluoromethyl, trifluoroethyl, phenyl, fluorophenyl or Chlorphenyl,

R³And R⁴For hydrogen atom, fluorine atom, chlorine atom, methyl or ethyl,

X is halogen atom；C₁~C₄Alkyl；C₂~C₃Alkynyl；Can be chosen free fluorine atom, chlorine atom, can be by 1~3 fluorine original The C of son substitution₁~C₂Alkyl and C₁~C₂The benzene of identical or different 1~2 substituent substitution in the group of alkoxy composition Base；Furyl, thienyl, oxazolyls or pyridine radicals, the furyl, thienyl, oxazolyls or pyridine radicals can be chosen free fluorine Atom, chlorine atom, the C that can be substituted by 1~3 fluorine atom₁~C₂Alkyl and C₁~C₂It is identical or not in the group of alkoxy composition Same 1~3 substituent substitution；Cyano group；Or N- hydroxyls-C₁~C₂Alkane imino group, the N- hydroxyls-C₁~C₂Alkane The hydrogen atom of hydroxyl can be chosen free C in imino group₁~C₂Substituent substitution in the group of alkyl and phenyl composition, n is 0~2 Integer,

Y is fluorine atom, chlorine atom or methyl, and m is 0 or 1；Or

Compound (A3), wherein, R¹And R²For methyl, ethyl, propyl group, trifluoromethyl, trifluoroethyl, phenyl, fluorophenyl or Chlorphenyl,

R³And R⁴For hydrogen atom, fluorine atom or methyl,

X is fluorine atom, chlorine atom, bromine atoms, methyl, acetenyl, furyl, thienyl, cyano group, Ethyl Methyl Ether imido Base, Ethoxyethane imino group or phenoxy group ethane imino group, n are 0 or 1,

Y is fluorine atom or methyl, and m is 0 or 1.

And then preferable compound (I) is：

(a-1) 3- (fluoro- 3,3- dimethyl -3, the 4- dihydro-isoquinoline -1- bases of 5-) quinoline,

(a-2) 3- (chloro- 3,3- dimethyl -3, the 4- dihydro-isoquinoline -1- bases of 5-) quinoline,

(a-3) 3- (bromo- 3,3- dimethyl -3, the 4- dihydro-isoquinoline -1- bases of 5-) quinoline,

(a-4) 3- (5- acetenyl -3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(a-5) 3- (5,6- bis- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(a-6) 3- (fluoro- 3- propyl group -3, the 4- dihydro-isoquinoline -1- bases of 3- ethyls -5-) quinoline,

(a-7) 3- (fluoro- 3- methyl -3- propyl group -3, the 4- dihydro-isoquinoline -1- bases of 5-) quinoline,

(a-8) 3- (3- methyl -3- trifluoromethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(a-9) 3- [3- methyl -3- (2,2,2- trifluoroethyl) -3,4- dihydro-isoquinoline -1- bases] quinoline,

(a-10) 3- [3- methyl -3- phenyl -3,4- dihydro-isoquinoline -1- bases] quinoline,

(a-11) 3- [3- methyl -3- (4- fluorophenyls) -3,4- dihydro-isoquinoline -1- bases] quinoline,

(a-12) 3- [3- methyl -3- (4- chlorphenyls) -3,4- dihydro-isoquinoline -1- bases] quinoline,

(a-13) 3- (3,3,4,4- tetramethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(a-14) 3- (tetramethyl -3, the 4- dihydro-isoquinoline -1- bases of 5- fluoro- 3,3,4,4-) quinoline,

(a-15) 3- (tetramethyl -3, the 4- dihydro-isoquinoline -1- bases of 5- fluoro- 3,3,4,4-) -6- fluorine quinolines Quinoline,

(a-16) 3- (tetramethyl -3, the 4- dihydro-isoquinoline -1- bases of 5- fluoro- 3,3,4,4-) -8- fluorine quinolines Quinoline,

(a-17) 3- (tetramethyl -3, the 4- dihydro-isoquinoline -1- bases of 5- fluoro- 3,3,4,4-) -8- methyl quinolines Quinoline,

(a-18) 3- (4,4- bis- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(a-19) 3- (4,5- bis- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline or

(a-20) 3- (4,4,5- tri- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline.

Compound (the I of the present invention：Group a compound) it is known compound, can be for example, by International Publication (WO) the Method or these described methods manufacture described in No. 2005/070917 specification.

For the compound of the group b in the present invention,

(B-1) compound preferably in following groups：

Group (1)：

Selected from (b-1-1) nitrile Fluoxastrobin,

(b-1-2) imines bacterium,

(b-1-3) pyraclostrobin,

(b-1-4) ZEN 90160,

(b-1-5) fluoxastrobin,

(b-1-6) dimoxystrobin,

(b-1-7) orysastrobin,

(b-1-8) pitch phenalgin acid amides and

(b-1-9) trifloxystrobin

In methoxy acrylic ester compounds；

Group (2)：

Selected from (b-2-1) simeconazoles,

(b-2-2) Tebuconazole,

(b-2-3) RH-7592,

(b-2-4) hexaconazole,

(b-2-5) acid amides azoles,

(b-2-6) triazolone,

(b-2-7) fluorine ether azoles,

(b-2-8) prothioconazoles,

(b-2-9) triticonazole,

(b-2-10) oxole bacterium,

(b-2-11) cycltebuconazole,

(b-2-12) the azoles bacterium of ring penta,

(b-2-13) propiconazole,

(b-2-14) cyproconazole,

(b-2-15) Difenoconazoles,

(b-2-16) olefin conversion,

(b-2-17) Fluquinconazole,

(b-2-18) Flusilazole,

(b-2-19) penconazole,

(b-2-20) bromuconazole,

(b-2-21) triadimenol,

(b-2-22) Flutriafol,

(b-2-23) nitrile bacterium azoles,

(b-2-24) etaconazole and

(b-2-25) Bitertanol

In triazole class compounds；

Group (3)：

Selected from (b-3-1) Evil oxpoconazole fumarates,

(b-3-2) fluorine bacterium azoles,

(b-3-3) IMAZALIL,

(b-3-4) IMAZALIL-S,

(b-3-5) Prochloraz,

(b-3-6) pefurazoate and

(b-3-7) azoles bacterium piperazine

In glyoxaline compound,

Group (4)：

Selected from (b-4-1) pyrrole metsulfovax,

(b-4-2) flutolanil,

(b-4-3) furan pyrazoles spirit,

(b-4-4) Boscalid,

(b-4-5) fenhexamid,

(b-4-6) cyflufenamid,

(b-4-7) tecloftalam,

(b-4-8) mandipropamid,

(b-4-9) Bixafen,

(b-4-10) carboxin,

(b-4-11) oxycarboxin,

(b-4-12) the third oxygen mebenil,

(b-4-13) Silthiopham,

(b-4-14) thifluzamide,

(b-4-15) fluorine biphenyl bacterium,

(b-4-16) Guardian,

(b-4-17) zoxamide,

(b-4-18) tiadinil,

(b-4-19) isotianil,

(b-4-20) double chlorine zarilamid,

(b-4-21) zarilamid,

(b-4-22) fluopicolide,

(b-4-23) fluopyram,

(b-4-24) carpropamide,

(b-4-25) Tolfenpyrad,

In Carbox amide；

Group (5)：

Selected from (b-5-1) metalaxyl,

(b-5-2) metalaxyl-M,

(b-5-3) M 9834,

(b-5-4) M 9834-M and

(b-5-5) furalaxyl-M

In acylalaninies class compound；

Group (6)：

Valyl aminated compounds in (b-6-1) benzene metsulfovax and (b-6-2) iprovalicarb；

Group (7)：

Selected from (b-7-1) cyazofamid,

(b-7-2) amisulbrom and

(b-7-3) flusulfamide

In sulfamide compound；

Group (8)：

Sulfinylamines compound in (b-8-1) tolyfluanid and (b-8-2) Euparen；

Group (9)：

Selected from (b-9-1) hundred dimension spirit,

(b-9-2) the hundred clever hydrochlorides of dimension,

(b-9-3) diethofencarb and

(b-9-4) Bi Li benzene card cloths

In carbamate compound；

Group (10)：

Selected from (b-10-1) Mancozeb (Mancozeb),

(b-10-2) maneb,

(b-10-3) propineb,

(b-10-4) zineb,

(b-10-5) Carbatene,

(b-10-6) ziram,

(b-10-7) thiuram and

(b-10-8) polycarbamate

In dithio amino formate compounds；

Group (11)：

Selected from (b-11-1) isopropyl it is fixed,

(b-11-2) procymidone,

(b-11-3) captan,

(b-11-4) vinclozolin,

(b-11-5) chlozolinate and

(b-11-6) folpet

In dicarboximide class compound；

Group (12)

Selected from the octyl benzene sulfonate of (b-12-1) biguanides three,

(b-12-2) iminoctadine triacetate,

(b-12-3) Guanoctine and

(b-12-4) dodine

In guanidine compound；

Group (13)：

Selected from (b-13-1) mepanipyrim,

(b-13-2) fenarimol,

(b-13-3) ferimzone,

(b-13-4) cyprodinil,

(b-13-5) dimethyl mepanipyrim,

(b-13-6) nuarimol,

(b-13-7) Milcurb,

(b-13-8) spirit of sulphur phonetic bacterium and

(b-13-9) fluorine mepanipyrim

In pyrimidines；

Group (14)：

Selected from (b-14-1) dimethomorph,

(b-14-2) butadiene morpholine,

(b-14-3) tridemorph,

(b-14-4) dodemorfe and

(b-14-5) flumorph

In morpholine kind compound；

Group (15)：

Selected from (b-15-1) thiophanate,

(b-15-2) thiophanate methyl,

(b-15-3) benomyl,

(b-15-4) carbendazim,

(b-15-5) Apl-Luster and

(b-15-6) furidazol

In benzimidazoles compound；

Group (16)：

Selected from (b-16-1) Fu Evil bacterium,

(b-16-2) fluoromide and

(b-16-3) fenpiclonil

In azoles；

Group (17)：

Selected from (b-17-1) fosetyl,

(b-17-2) Hinosan,

(b-17-3) tolelofos-methyl,

(b-17-4) different rice blast net and

(b-17-5) Ppyrazophos

In organophosphorus compound；

Group (18)：

Selected from (b-18-1) Kocide SD,

(b-18-2) copper,

(b-18-3) basic copper chloride,

(b-18-4) basic copper sulfate,

(b-18-5) copper 8-hydroxyquinolinate,

(b-18-6) cupric sulfate pentahydrate,

(b-18-7) anhydrous cupric sulfate,

(b-18-8) nonyl benzene copper phenolsulfonate and

(b-18-9) DBSA bis ethylene diamine copper complex salt

In copper class compound；

Group (19)：

Selected from (b-19-1) kasugarnycin,

(b-19-2) valida,

(b-19-3) polyoxin A~N,

(b-19-4) blasticidin-S S benzylaminos benzene sulfonate,

(b-19-5) streptomysin,

(b-19-6) natamycin,

(b-19-7) midolthromycin and

(b-19-8) terramycin

In antibiotic；

Group (20)：

Selected from (b-20-1) Bravo,

(b-20-2) phthalide and

(b-20-3) pentachloronitrobenzene

In organochlorine class compound；

Group (21)：

In triazolopyrimidines；

Group (22)：

Selected from (b-22-1) table metrafenone and (b-22-2) 3- (2,3,4- trimethoxy -6- toluyls Base) benzoyl compound in the chloro- 2- methoxyl groups -4- picolines of -5-；

Group (23)

In ethylenediamines compound；

Group (24)：

In isoxazole alkyl compound；

Group (25)：

Selected from (b-25-1) quinoxyfen,

In quinolines；

Group (26)：

In thiazolidine compounds；

Group (27)：

In pyrazoline ketone compounds；And

Group (28)：

Selected from (b-28-1) hydroxyisoxazole,

(b-28-2) fluazinam,

(b-28-3) diclomezine,

(b-28-4) tricyclazole,

(b-28-5) cymoxanil,

(b-28-6) azolactones bacterium,

(b-28-7) Fenamidone,

(b-28-8) chloropicrin,

(b-28-9) thiadiazine,

(b-28-10) the third oxygen quinoline,

(b-28-11) Loazolamines,

(b-28-12) fenpropidin,

(b-28-13) Delan,

(b-28-14) Pencycuron,

(b-28-15) Isoprothiolane,

(b-28-16) probenazole,

(b-28-17) resveratrol,

(b-28-18) triforine,

(b-28-19) thiadiazoles element-S- methyl,

(b-28-20) pyroquilon,

(b-28-21) dinocap,

(b-28-22) dimethylamino aminodithioformic acid nickel,

(b-28-23) kobam,

(b-28-24) Evil frost spirit,

(b-28-25) ambam,

(b-28-26) pyrifenox,

(b-28-27) oxolinic acide and

(b-28-28) phosphorous acid

In other sterilization fungicidal agents；

(B-2) and then, the compound in preferably following groups：

Group (1)：

Selected from (b-1-1) nitrile Fluoxastrobin,

(b-1-2) imines bacterium,

(b-1-3) pyraclostrobin,

(b-1-4) ZEN 90160,

(b-1-5) fluoxastrobin,

(b-1-6) dimoxystrobin,

(b-1-7) orysastrobin,

(b-1-8) pitch phenalgin acid amides and

(b-1-9) trifloxystrobin

In methoxy acrylic ester compounds；

Group (2)：

Selected from (b-2-1) simeconazoles,

(b-2-2) Tebuconazole,

(b-2-3) RH-7592,

(b-2-4) hexaconazole,

(b-2-5) acid amides azoles,

(b-2-6) triazolone,

(b-2-7) fluorine ether azoles,

(b-2-8) prothioconazoles,

(b-2-9) triticonazole,

(b-2-10) oxole bacterium,

(b-2-11) cycltebuconazole,

(b-2-12) the azoles bacterium of ring penta,

(b-2-13) propiconazole,

(b-2-14) cyproconazole,

(b-2-15) Difenoconazoles,

(b-2-16) olefin conversion,

(b-2-17) Fluquinconazole and

(b-2-18) Flusilazole

In triazole class compounds；

Group (3)：

Selected from (b-3-1) Evil oxpoconazole fumarates,

(b-3-2) fluorine bacterium azoles,

(b-3-3) IMAZALIL,

(b-3-4) IMAZALIL-S and

(b-3-5) Prochloraz

In glyoxaline compound；

Group (4)：

Selected from (b-4-1) pyrrole metsulfovax,

(b-4-2) flutolanil,

(b-4-3) furan pyrazoles spirit,

(b-4-4) Boscalid,

(b-4-5) fenhexamid,

(b-4-6) cyflufenamid,

(b-4-7) tecloftalam,

(b-4-8) mandipropamid,

(b-4-9) Bixafen,

(b-4-10) carboxin,

(b-4-11) oxycarboxin,

(b-4-12) the third oxygen mebenil,

(b-4-13) Silthiopham,

(b-4-14) thifluzamide,

(b-4-15) fluorine biphenyl bacterium,

(b-4-16) Guardian,

(b-4-17) zoxamide,

(b-4-18) tiadinil,

(b-4-19) isotianil,

(b-4-20) double chlorine zarilamid,

(b-4-21) zarilamid,

(b-4-22) fluopicolide,

(b-4-23) fluopyram,

(b-4-24) carpropamide,

(b-4-25) Tolfenpyrad,

(b-4-29) 3- (difluoromethyl)-N- [4 '-(3,3- dimethyl butine -1- bases) biphenyl -2- Base] -1- methyl isophthalic acid H- pyrazole-4-carboxamides and

(b-4-30) [4 '-(3- methoxyl group -3- methyl butyne -1- bases) joins 3- (difluoromethyl)-N- Benzene -2- bases] -1- methyl isophthalic acid H- pyrazole-4-carboxamides

In Carbox amide；

Group (5)：

Selected from (b-5-1) metalaxyl,

(b-5-2) metalaxyl-M,

(b-5-3) M 9834 and

(b-5-4) M 9834-M

In acylalaninies class compound；

Group (6)：

Group (7)：

Selected from (b-7-1) cyazofamid,

(b-7-2) amisulbrom and

(b-7-3) flusulfamide

In sulfamide compound；

Group (8)：

Sulfinylamines compound in (b-8-1) tolyfluanid and (b-8-2) Euparen；

Group (9)：

Selected from (b-9-1) hundred dimension spirit,

(b-9-2) the hundred clever hydrochlorides of dimension,

(b-9-3) diethofencarb and

(b-9-4) Bi Li benzene card cloths

In carbamate compound；

Group (10)：

Selected from (b-10-1) Mancozeb (Mancozeb),

(b-10-2) maneb,

(b-10-3) propineb,

(b-10-4) zineb,

(b-10-5) Carbatene,

(b-10-6) ziram,

(b-10-7) thiuram and

(b-10-8) polycarbamate

In dithio amino formate compounds；

Group (11)

Selected from (b-11-1) isopropyl it is fixed,

(b-11-2) procymidone,

(b-11-3) captan,

(b-11-4) vinclozolin,

(b-11-5) chlozolinate and

(b-11-6) folpet

In dicarboximide class compound；

Group (12)：

Selected from the octyl benzene sulfonate of (b-12-1) biguanides three,

(b-12-2) iminoctadine triacetate,

(b-12-3) Guanoctine and

(b-12-4) dodine

In guanidine compound；

Group (13)：

Selected from (b-13-1) mepanipyrim,

(b-13-2) fenarimol,

(b-13-3) ferimzone,

(b-13-4) cyprodinil and

(b-13-5) dimethyl mepanipyrim

In pyrimidines；

Group (14)：

Selected from (b-14-1) dimethomorph,

(b-14-2) butadiene morpholine,

(b-14-3) tridemorph,

(b-14-4) dodemorfe and

(b-14-5) flumorph

In morpholine kind compound；

Group (15)：

Selected from (b-15-1) thiophanate,

(b-15-2) thiophanate methyl,

(b-15-3) benomyl,

(b-15-4) carbendazim,

(b-15-5) Apl-Luster and

(b-15-6) furidazol

In benzimidazoles compound；

Group (16)：

Selected from (b-16-1) Fu Evil bacterium,

(b-16-2) fluoromide and

(b-16-3) fenpiclonil

In azoles；

Group (17)：

Selected from (b-17-1) fosetyl,

(b-17-2) Hinosan and

(b-17-3) tolelofos-methyl

In organophosphorus compound；

Group (18)：

Selected from (b-18-1) Kocide SD,

(b-18-2) copper,

(b-18-3) basic copper chloride,

(b-18-4) basic copper sulfate,

(b-18-5) copper 8-hydroxyquinolinate,

(b-18-6) cupric sulfate pentahydrate and

(b-18-7) anhydrous cupric sulfate

In copper class compound；

Group (19)：

Selected from (b-19-1) kasugarnycin,

(b-19-2) valida,

(b-19-3) Polyoxin AL and D

(b-19-4) blasticidin-S S benzylaminos benzene sulfonate and

(b-19-5) streptomysin

In antibiotic；

Group (20)：

Selected from (b-20-1) Bravo,

(b-20-2) phthalide and

(b-20-3) pentachloronitrobenzene

In organochlorine class compound；

Group (21)：

In triazolopyrimidines；

Group (22)：

Selected from (b-22-1) table metrafenone and

In benzoyl compound；

Group (23)：

In ethylenediamines compound；

Group (24)：

For (b-24-1) 3- [5- (4- chlorphenyls) -2,3- dimethyl isoxazole alkane -3- bases] pyridine Yi Evil Azoles alkyl compound；

Group (25)：

Selected from (b-25-1) quinoxyfen and

(b-25-2) [fluoro- 2, the 3- dimethyl quinolines -4- bases of 6- (1,1- dimethyl ethyl) -8-] acetic acid esters

In quinolines；

Group (26)：

For (b-26-1) (2Z)-{ [2- fluoro- 5- (trifluoromethyl) phenyl] sulphur } [3- (2- methoxyphenyls)- 1,3-thiazoles alkane -2- subunits] acetonitrile thiazolidine compounds；

Group (27)：

For (b-27-1) 1- [(2- acrylic sulfenyl) carbonyl] -2- (1- Methylethyls) -4- (2- methylbenzenes Base) -5- amino -1H- pyrazoles -3- ketone pyrazoline ketone compounds；And

Group (28)：

Selected from (b-28-1) hydroxyisoxazole,

(b-28-2) fluazinam,

(b-28-3) diclomezine,

(b-28-4) tricyclazole,

(b-28-5) cymoxanil,

(b-28-6) azolactones bacterium,

(b-28-7) Fenamidone,

(b-28-8) chloropicrin,

(b-28-9) thiadiazine,

(b-28-10) the third oxygen quinoline,

(b-28-11) Loazolamines,

(b-28-12) fenpropidin,

(b-28-13) Delan,

(b-28-14) Pencycuron,

(b-28-15) Isoprothiolane,

(b-28-16) probenazole,

(b-28-17) resveratrol,

(b-28-18) triforine,

(b-28-19) thiadiazoles element-S- methyl,

(b-28-20) pyroquilon,

(b-28-21) dinocap,

(b-28-27) oxolinic acide and

(b-28-28) phosphorous acid

In other sterilization fungicidal agents；

(B-3) further preferably by the compound in the following groups of groups formed：

Group (1)：

Methoxy acrylic ester compounds in (b-1-1) nitrile Fluoxastrobin and (b-1-2) imines bacterium；

Group (2)：

Selected from (b-2-1) simeconazoles,

(b-2-2) Tebuconazole,

(b-2-3) RH-7592,

(b-2-4) hexaconazole,

(b-2-5) acid amides azoles and

(b-2-6) triazolone

In triazole class compounds；

Group (3)：

Selected from (the glyoxaline compound in b-3-1) Evil oxpoconazole fumarates and (b-3-2) fluorine bacterium azoles；

Group (4)：

Selected from (b-4-1) pyrrole metsulfovax,

(b-4-2) flutolanil,

(b-4-3) furan pyrazoles spirit,

(b-4-4) Boscalid,

(b-4-5) fenhexamid,

(b-4-6) cyflufenamid and

(b-4-7) tecloftalam

In Carbox amide；

Group (5)：

Selected from (b-5-1) metalaxyl,

(b-5-2) metalaxyl-M,

(b-5-3) M 9834 and

(b-5-4) M 9834-M

In acylalaninies class compound；

Group (6)：

For the valyl aminated compounds of (b-6-1) benzene metsulfovax；

Group (7)：

For the sulfamide compound of (b-7-1) cyazofamid；

Group (9)：

The carbamate compound in clever hydrochloride and (b-9-2) diethofencarb is tieed up selected from (b-9-1) hundred；

Group (10)：

Aminodithioformic acid in (b-10-1) Mancozeb (Mancozeb) and (b-10-2) maneb Ester type compound；

Group (11)：

Selected from (b-11-1) isopropyl it is fixed,

(b-11-2) procymidone and

(b-11-3) captan

In dicarboximide class compound；

Group (12)：

For the guanidine compound of the octyl benzene sulfonate of (b-12-1) biguanides three；

Group (13)：

Selected from (b-13-1) mepanipyrim,

(b-13-2) fenarimol and

(b-13-3) ferimzone

In pyrimidines；

Group (14)：

For the morpholine kind compound of (b-14-1) dimethomorph；

Group (15)：

For the benzimidazoles compound of (b-15-1) thiophanate methyl；

Group (16)：

For (the azoles of b-16-1) Fu Evil bacterium；

Group (18)：

For the copper class compound of (b-18-1) Kocide SD；

Group (19)：

Selected from (b-19-1) kasugarnycin,

(b-19-2) valida and

(b-19-3) Polyoxin AL and D

In antibiotic；

Group (20)：

Organochlorine class compound in (b-20-1) Bravo and (b-20-2) phthalide；

Group (23)：

In ethylenediamines compound；And

Group (28)：

Selected from (b-28-2) fluazinam,

(b-28-3) diclomezine,

(b-28-4) tricyclazole

(b-28-5) cymoxanil and

(b-28-6) azolactones bacterium

In other sterilization fungicidal agents.

The compound of group b in the present invention is known compound, can according to for example " The Pesticide Manual, 14 editions, British Crop Protection Council Pubn., 2006 ", International Publication (WO) the 1997/15552nd Specification, No. 2003/070705 specification of International Publication (WO), AGROW No.243 (1995), International Publication (WO) No. 1999/024413 specification, No. 2004/016088 specification of International Publication (WO), International Publication (WO) the 2003/th No. 010149 specification, No. 2003/74491 specification of International Publication (WO), International Publication (WO) the 2004/35589th are said Bright book, No. 2004/58723 specification of International Publication (WO), No. 1999/21851 specification of International Publication (WO), international public affairs Open (WO) No. 2001/10825 specification, International Publication (WO) No. 1998/46607 specification, Japanese Unexamined Patent Publication 2000- No. 2006/87325 No. 119275 publications, No. 2002/38565 specification of International Publication (WO), International Publication (WO) explanation Book, No. 2005/87773 specification of International Publication (WO), International Publication (WO) No. 2002/02527 specification, International Publication (WO) No. 2003/008372 specification, No. 2005/042474 specification of International Publication (WO), International Publication (WO) No. 2007/111024 specification, Japanese Unexamined Patent Publication 2006-282508 publications, Japanese Unexamined Patent Publication 2000-281678 public affairs Report, No. 2001/92231 specification of International Publication (WO), Japanese Unexamined Patent Publication 2000-319270 publications and Japanese Unexamined Patent Publication Method or these described methods described in 2000-226374 publications are manufactured.

Compared with the situation of each active ingredient is used alone, plant disease control composition of the invention can be assisted Same preventive effect.

Plant disease control composition in the present invention, direct use, but be generally used in mixed way with carrier, according to need Will, the preparation adjuvant such as surfactant, wetting agent, adhesive, thickener, preservative, colouring agent, stabilizer can be added, Using commonly known method, the preparations such as wettable powder, suspending agent, water dispersion granule, pulvis, emulsion, which are in time made, to be made With.Quinoline compound (the I as active ingredient in above-mentioned preparation：Group a compound) content, with weight ratio meter, generally For 0.005~99% scope, preferably 0.01~90% scope, more preferably 0.1~85% scope.It is in addition, above-mentioned The content of the bactericidal properties compound of the group b as active ingredient in preparation, with weight ratio meter, usually 0.005~99% Scope, preferably 0.1~90% scope, as quinoline compound (I：Group a compound) bactericidal properties compound with group b Total amount, with the scope of weight ratio meter, usually 0.005~99%, preferably 0.01~90% scope, more preferably 0.1~ 85% scope.Quinoline compound (I：Group a compound) with group b bactericidal properties compound mixing ratio, using weight ratio meter as Following ratios：Under normal circumstances, it is 0.01~1000 relative to the bactericidal properties compound of quinoline compound 1, group b, preferably relatively In quinoline compound 1, organize b bactericidal properties compound be 0.1~100.

In the plant disease control composition of the present invention, quinoline compound (I：Group a compound) with group b bactericidal properties Total active constituent content of compound, it is different and different with dosage form, but be generally as follows：It is 0.01~30 in pulvis Weight %, it is 0.1~80 weight % in wettable powder, is 0.5~20 weight % in granule, is 2 in emulsion ~50 weight %, it is 1~50 weight % in suspending agent, is 1~80 weight % in dry suspending agent.It is preferably as follows：In powder It is 0.05~10 weight % in agent, is 5~60 weight % in wettable powder, is 5~20 weight % in emulsion, It is 5~50 weight % in suspending agent, is 5~50 weight % in dry suspending agent.In addition, the content of adjuvant is 0~80 weight % is measured, the content of carrier is that amount obtained from active ingredient compound and the content of adjuvant is subtracted from 100 weight %.

The carrier used in above-mentioned composition refers to, in order to help active ingredient arrival to answer treatment site and make effectively The synthesis or natural inorganic or organic substance that storage, transport, the processing of component cpd are easily carried out and coordinated, as long as being logical The material used in normal agricultural or horticultural use medicine, can be used any of solid or liquid, there is no particular restriction.Solid carries Body for example can be bentonite, montmorillonite, kaolinite, diatomite, clay, talcum powder, clay, vermiculite, gypsum, calcium carbonate, nothing The inorganic substances such as amorphous silicon dioxide, ammonium sulfate；The plants such as soy meal, wood powder, sawdust, wheat flour, lactose, sucrose, glucose Property organic substance；Or urea etc..Liquid-carrier is aromatic hydrocarbon such as can be toluene, dimethylbenzene, cumene and cycloalkanes Class；Normal paraffin hydrocarbons (n-paraffin), isoparaffin (iso-paraffin), atoleine, kerosene, mineral oil, polybutene etc. Paraffin class hydro carbons；The ketones such as acetone, methyl ethyl ketone；The ethers such as dioxane, diethylene glycol dimethyl ether；Ethanol, propyl alcohol, The alcohols such as ethylene glycol；The carbonates such as ethylene carbonate, propylene carbonate, butylene carbonate；Dimethylformamide, dimethyl are sub- The non-protonic solvents such as sulfone；Or water etc..

And then in order to strengthen the effect of the compound in the composition of the present invention, it is contemplated that formulation, the processing method of preparation Deng individually or adjuvant can also be applied in combination according to purpose.As above-mentioned adjuvant, generally, in order to by pesticidal preparations Emulsification, scattered, extension and/or wetting etc. and the surfactant used, such as can be sorbitan fatty acid ester, polyoxy Ethene sorbitan fatty acid ester, fatty acid cane sugar ester, polyoxyethylene fatty acid ester, polyoxyethylene resin acid ester, polyoxy second Alkene fatty acid diesters, Emulsifier EL-60, polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene dialkyl group Phenyl ether, the formaldehyde condensation products of polyoxyethylene alkyl phenyl ether, polyoxyethylene polyoxypropylene block polymer, alkyl polyoxyethylene Polyoxypropylene block polymer ether, alkyl phenyl polyethylene oxides polyoxypropylene block polymer ether, polyoxyethylene alkyl amine, polyoxy It is the double phenyl ether of ethene fatty acid amide, polyoxyethylene, polyoxyalkylene benzyl phenyl ether, polyoxyalkylene styrylphenyl ether, advanced The polyoxyalkylene addition product and APEO and the non-ionic surfactant such as ester type organosilicon and fluorine class surfactant of alcohol Agent；Alkyl sulfate, polyoxyethylene alkyl ether sulfuric ester, polyoxyethylene alkyl phenyl ether sulfuric ester, polyoxyethylene benzyl phenyl Ether sulfuric ester, polyoxyethylene styryl phenyl ether sulfuric ester, polyoxyethylene polyoxypropylene block polymer sulfuric ester, paraffin hydrocarbon Sulfonate, alkylsulfonate, AOS, dialkyl sulfosuccinate, alkylbenzenesulfonate, naphthalene sulfonate, dialkyl napthalene sulfonic acids Salt, the formaldehyde condensation products of naphthalene sulfonate, alkyl diphenyl base ether disulfonate, lignosulphonates, polyoxyethylene alkyl phenyl ether sulphur Hydrochlorate, polyoxyethylene alkyl ether sulfosuccinic acid semiester, soap, N- methyl-fatty acid sarcosinates, resinate, Ether phosphates, polyoxyethylene phenyl ether phosphate, polyoxyethylene dialkyl phenyl organic ether phosphate, polyoxyethylene The Benzylation phenyl ether phosphate of Benzylation phenyl ether phosphate, polyoxyethylene, polyoxyethylene styrene base phenyl ether phosphorus Hydrochlorate, polyoxyethylene styrene base phenyl ether phosphate, polyoxyethylene polyoxypropylene block polymer phosphate, phosphatide The anionic surfactant such as phatidylcholine, phosphatidyl ethanol imines, alkylphosphonate, sodium tripolyphosphate；By acrylic acid and third Polyanionic high molecular surfactant, alkyl trimethyl ammonium chloride, methyl derived from alkene nitrile, acrylamido methylpropane sulfonic acid Polyxyethylated ammonium chloride, alkyl N-methyl pyridinium bromide, monomethylation ammonium chloride, dialkyl methyl ammonium chloride, alkyl The cationic surface active agents such as pentamethyl propylene dichloride amine, alkyl dimethyl benzalkonium chloride, benzethonium chloride；Or dialkyl group two Amphoteric surfactantes such as amino-ethyl glycine betaine, alkyldimethylbenzylammonium glycine betaine etc..Used as above-mentioned adjuvant viscous Mixture, such as can be mosanom, polyvinyl alcohol, Arabic gum, CMC sodium or bentonite etc., disintegrant for example can be CMC sodium Or Ac-Di-Sol, stabilizer for example can be that hindered phenol anti-oxidants or benzotriazole, hindered amines are purple Ultraviolet absorbers etc..PH adjusting agent for example can be phosphoric acid, acetic acid or sodium hydroxide, and fungi-proofing mould inhibitor for example can be 1,2- The industrial bactericide such as benzisothiazole-3-ketone, fungi-proofing mould inhibitor etc..Thickener for example can be xanthans, guar gum, CMC sodium, Arabic gum, polyvinyl alcohol or montmorillonite etc..Defoamer for example can be organosilicon compound, and antifreezing agent for example may be used To be propane diols or ethylene glycol etc..But these adjuvants are not limited to above-mentioned substance.

The application process of the present composition, such as can be cauline leaf distribution processing to plant individual, seedling box processing, right The distribution processing of soil surface, the soil mixing after soil surface distribution processing, the injection into soil are handled, in soil The soil after soil mixing, soil-perfusion processing, soil-perfusion processing after injection processing mixes, to the place that sows grass seeds by duster of vegetable seeds Manage, to smearing processing, the impregnation to vegetable seeds or Cotton seeds to vegetable seeds of vegetable seeds etc., using ability Any application process that field technique personnel generally utilize can play sufficient effect.

In addition, the method for preventing and kill off plant disease in the present invention, including apply the compound (I) containing group a and group b Plant disease control composition of the bactericidal properties compound as active ingredient, or the compound (I) containing group a is administered simultaneously and makees Plant disease control composition for active ingredient and the bactericidal properties compound for containing group b are prevented as the plant disease of active ingredient Except composition, or the compound (I) containing group a is being applied as the plant disease control composition of active ingredient or is containing a group b Bactericidal properties compound as after either one in the plant disease control composition of active ingredient, spread above-mentioned group of the opposing party The method of compound, the compound (I) containing group a is being applied as the plant disease control composition of active ingredient or is containing a group b Bactericidal properties compound as after either one in the plant disease control composition of active ingredient, until spreading the upper of the opposing party The time (period) of composition, for example, 1 minute~2 weeks after either one is applied are stated, preferably using 5 points after either one Clock~1 week, more preferably using 10 minutes after either one~3 days.

And then plant disease control composition of the invention can prepare and contain quinoline compound (I) with high concentration and organize b's The composition of bactericidal properties compound.Above-mentioned high concentration composition dilutable water, which is made, spreads liquid use.In addition, the plant of the present invention Thing disease prevents and kill off composition can also contain by the composition for containing quinoline compound (I) with high concentration and with high concentration when in use The composition for having group b bactericidal properties compound mixes, and prepares resulting mixture.Above-mentioned high concentration composition dilutable water is made scattered Cloth liquid uses (tank mixes method).

Prevent for the quinoline compound (I) for containing group a and the bactericidal properties compound for organizing b as the plant disease of active ingredient For composition, amount of application and application concentration are with object crop, the agent of object disease, the occurrence degree of disease, compound The difference of type, application process and various environmental conditions etc. and changes, in distribution, as active ingredient amount, usually per hectare 50~10,000g, preferably per hectare 100~5,000g.In addition, enter wettable powder, suspending agent or emulsion is diluted with water When row is spread, its extension rate is usually 5~50,000 times, and preferably 10~20,000 times, more preferably 15~10,000 times. In addition, in seed disinfection, the usage amount of fungicide mixture be usually per 1kg 0.001~50g of seed, preferably 0.01~ 10g.When the processing of the cauline leaf distribution to plant individual, the distribution processing to soil surface are carried out to the present composition, to soil In injection processing, soil-perfusion processing when, also can be after the medicine used be diluted into appropriate concentration with appropriate carrier Handled.When making the present composition be contacted with vegetable seeds, directly vegetable seeds can be immersed in medicine.In addition, Also vegetable seeds can be impregnated, be coated, sprayed after the medicine used is diluted into appropriate concentration in appropriate carrier Broadcast, smearing processing.The preparation usage amount sowed grass seeds by duster when smearing processing is coated, usually dried plant seed weight 0.05~50% or so, preferably 0.1~30%, but above-mentioned usage amount is not limited to above range, can be with dosage form or work Change for the vegetable seeds species difference of process object.The liquid of appropriate carrier organic solvent such as can be water or ethanol Body carrier；Bentonite, montmorillonite, kaolinite, diatomite, clay, talcum powder, clay, vermiculite, gypsum, calcium carbonate, amorphous two The vegetalitas such as the inorganic substances such as silica, ammonium sulfate, soy meal, wood powder, sawdust, wheat flour, lactose, sucrose, glucose are organic The solid carrier such as material or urea, but it is not limited to this.

Plant individual in this specification is the material for carrying out photosynthesis and living with not moving, specifically, such as Can be rice, wheat, barley, corn, grape, apple, pears, peach, cherry, persimmon, citrus, soybean, Kidney bean, strawberry, potato, Cabbage, lettuce, tomato, cucumber, eggplant, watermelon, beet, spinach, pea, pumpkin, sugarcane, tobacco, green pepper, sweet potato, taro, Amorphophalus rivieri, beet, cotton, sunflower, tulip, chrysanthemum or turfgrass etc., but it is not limited to this.

Vegetable seeds in this specification is the nutritional ingredient needed for storage plantling germination, is agriculturally being used for what is bred Material, specifically, such as can be corn and soybean, cotton, rice, preserved carrot, wheat, barley, sunflower, tomato, cucumber, eggplant The seed of son, spinach, pea, pumpkin, sugarcane, tobacco, green pepper and cabbage type rape etc.；Taro, potato, sweet potato, Amorphophalus rivieris etc. Potato seed；Bulb of the napiform root of edible lily, tulip etc. or Chinese onion etc. etc.；It is and caused to the progress manual operation such as gene Plant, the plant is such as can be soybean that nature is not present originally, imparting herbicide tolerance, corn, cotton；Adapt to The rice of cold region, tobacco etc.；Inverted seeds such as the corn of insect killing substance production capacity, cotton, potato etc. are imparted, But it is not limited to this.

Certainly, composition of the invention also can be with other insecticides, acaricide, nematicide, herbicide and plant growth The agricultural chemicals such as conditioning agent, soil conditioner or fertilizer efficiency material mixing use, and also mix preparation can be made with above-mentioned substance.Insecticide example Such as can be Folithion, basudin, pyridaphethione, chlopyrifos, marathon, phenthoate dimephenthoate cidial, Rogor, thimet (methylthiometon), the Phosphorus insecticide such as Toyodan, DDVP, orthene, salithion, EPN；NAC、MTMC、 The carbamate insecticides such as BPMC, Aphox, carbosulfan, methomyl；Ethofenprox, deinsectization silicon ether, Permethrin, killing The pyrethroid insecticideses such as chrysanthemum ester；MTI-446, clothianidin, nitenpyram, Diacloden, imidacloprid, thiacloprid, acetamiprid etc. Anabasine insecticide, Frontline and ethiprole etc., but it is not limited to this.

The composition and the method for control of the present invention is for example effective to the plant disease of following species.Hereinafter, exemplified as this The specific disease of the control object of invention and its pathogen.

Can be rice blast (Pyricularia oryzae), the banded sclerotial blight (Thanatephorus of rice Cucumeris), water rice brown spot (Cochliobolus miyabeanus), bakanae disease (Gibberella Fujikuroi), seedling blight (Pythium spp., Fusarium spp., Trichoderma spp., Rhizopus Spp., Rhizoctonia solani etc.), false smut (Claviceps virens), smut (Tilletia barelayana)；Powdery mildew (the Erysiphe graminis f.sp.hordei of wheat class；F.sp.tritici), rust (Puccinia striiformis；Puccinia graminis、Puccinia recondita、Puccinia hordei)、 Stripe disease (Pyrenophora graminea), net blotch (Pyrenophora teres), head blight (Fusarium Graminearum, Fusarium culmorum, Fusarium avenaceum, Microdochium nivale), snow mold (Typhula incarnata, Typhula ishikariensis, Micronectriella nivalis), smut (Ustilago nuda, Ustilago tritici, Ustilago nigra, Ustilago avenae), bunt (Tilletia caries, Tilletia pancicii), eye spot (Pseudocercosporella Herpotrichoides), banded sclerotial blight (Rhizoctonia cerealis), moire disease (Rhynchosporium secalis), Leaf blight (Septoria tritici), glume blight (Leptosphaeria nodorum), seedling blight (Fusarium Spp., Pythium spp., Rhizoctonia spp., Septoria nodorum, Pyrenophora spp.), damping-off (Gaeumannomyces graminis), anthracnose (Colletotrichum gramaminicola), ergot (Claviceps purpurea), spot disease (Cochliobolus sativus)；Head blight (the Fusarium of corn Graminearum etc.), seedling blight (Fusarium avenaceum, Penicillium spp, Pythium spp., Rhizoctonia spp), rust (Puccinia sorghi), flax leaf blight (Cochliobolus Heterostrophus), smut (Ustilago maydis), anthracnose (Colletotrichum gramaminicola), Helminthosporium carbonum (Cochliobolus carbonum)；

The downy mildew (Plasmopora viticola) of grape, rust (Phakopsora ampelopsidis), white powder It is sick (Uncinula necator), anthrachose of grape (Elsinoe ampelina), late blight (Glomerella cingulata), black Maize ear rot (Guignardia bidwellii), dead arm (Phomopsis viticola), coal point disease (Zygophiala Jamaicensis), gray mold (Botrytis cinerea), bud blight (Diaporthe medusaea), purple root rot (Helicobasidium mompa) (Helicobasidium mompa), white root rot (Rosellinia necatrix)；Powdery mildew (the Podosphaera of apple Leucotricha), scab (Venturia inaequalis), spot defoliation (Alternaria alternata (Apple pathotype)), rust (Gymnosporangium yamadae), blossom rot (Monillia mali), rot Sick (Valsa ceratosperma), ring spot (Botryosphaeria berengeriana), anthracnose (Colletotrichum acutatum), coal point disease (Zygophiala jamaicensis), coal spot disease (Gloeodes Pomigena), diplostomiasis (Mycosphaerella pomi), purple root rot (Helicobasidium mompa) (Helicobasidium mompa), white root rot (Rosellinia necatrix), stem wilt (Phomopsis mali, Diaporthe tanakae), brown spot (Diplocarpon mali)；The black spot (Alternaria alternata (Japanese pear pathotype)) of pears, Scab (Venturia nashicola), rust (Gymnosporangium haraeanum), ring spot (Physalospora piricola), stem wilt (Diaporthe medusaea, Diaporthe eres)；The epidemic disease of European pear Sick (Phytophthora cactorum)；The scab (Cladosporium carpophilum) of peach, Fungi point mold (Phomopsis sp.), epidemic disease (Phytophthora sp.), anthracnose (Gloeosporium laeticolor)；Cherry Anthracnose (Glomerella cingulata), young fruit sclerotiniose (Monilinia kusanoi), grey scab (Monilinia fructicola)；The anthracnose (Gloeosporium kaki) of persimmon, defoliation (Cercospora kaki； Mycosphaerella nawae), powdery mildew (Phyllactinia kakikora)；Diplostomiasis (the Diaporthe of citrus Citri), green mould (Penicilliumdigitatum), penicilliosis (Penicillium italicum), shot hole (Elsinoe fawcettii)；

Gray mold (the Botrytis of tomato, cucumber, beans, strawberry, potato, cabbage, eggplant, lettuce etc. cinerea)；The sclerotiniose of tomato, cucumber, beans, strawberry, potato, vegetable seed, cabbage, eggplant, lettuce etc. (Sclerotinia sclerotiorum)；Tomato, cucumber, beans, radish, watermelon, eggplant, vegetable seed, green pepper, spinach, beet etc. Seedling blight (Rhizoctonia spp., Pythium spp., Fusarium spp., the Phythophthora of various vegetables Spp., Sclerotinia sclerotiorum etc.)；It is melon downy mildew (Pseudoperonospora cubensis), white Powder disease (Sphaerotheca fuliginea), anthracnose (Colletotrichum lagenarium), blight dis-ease (Mycosphaerella melonis), dead arm (Fusarium oxysporum), epidemic disease (Phytophthora parasitica、Phytophthora melonis、Phytophthora nicotianae、Phytophthora Drechsleri, Phytophthora capsici etc.)；The ring spot (Alternaria solani) of tomato, leaf mold (Cladosporium fulvam), epidemic disease (Phytophthora infestans), droop (Fusarium Oxysporum), root rot (Pythium myriotylum, Pythium dissotocum), anthracnose (Colletotrichum phomoides)；Powdery mildew (Sphaerotheca fuliginea etc.), the sooty mould of eggplant (Mycovellosiella nattrassii), epidemic disease (Phytophthora infestans), brown rot (Phytophthora capsici)；Alternaria stem rot of colza (Alternaria brassicae)；The black spot of brassicaceous vegetable (Alternaria brassicae etc.), Leucoplakia (Cercosporella brassicae), Root―rot disease (Leptospheria Maculans), clubroot (Plasmodiophora brassicae), downy mildew (Peronospora brassicae)；Roll up the heart Banded sclerotial blight (Rhizoctonia solani), the chlorosis (Fusarium oxysporum) of dish；The buttocks maize ear rot of Chinese cabbage (Rhizoctonia solani), yellows (Verticillium dahlie)；It is the rust (Puccinia allii) of green onion, black Pinta (Alternaria porri), southern blight (Sclerotium rolfsii.Sclerotium rolfsii), white epidemic disease (Phytophthora porri)；The purple spot (Cercospora kikuchii) of soybean, anthrachose of grape (Elsinoe Glycinnes), diplostomiasis (Diaporthe phaseololum), rhizoctonia root rot (Rhizoctonia solani), stem Epidemic disease (Phytophthora megasperma), downy mildew (Peronospora manshurica), rust (Phakopsora Pachyrhizi), anthracnose (Colletotrichum truncatum)；Anthracnose (the Colletotrichum of Kidney bean lindemuthianum)；The black of peanut relates to disease (Mycosphaerella personatum), brown spot (Cercospora arachidicola)；Powdery mildew (Erysiphe pisi), the downy mildew (Peronospora pisi) of pea；The downy mildew of broad bean Sick (Peronospora viciae), epidemic disease (Phytophthora nicotianae)；The summer epidemic disease of potato (Alternaria solani), Rhizoctonia Disease (Rhizoctonia solani), epidemic disease (Phytophthora Infestans), silver-colored maize ear rot (Spondylocladium atrovirens), dry rot (Fusarium oxysporum, Fusarium solani), powdery scab (Spongospora subterranea)；Brown spot (the Cercospora of beet Beticola), downy mildew (Peronospora schachtii), black root (Aphanomyces cochioides), snake eye disease (Phoma batae)；The black leaf blight (Alternaria dauci) of carrot；Powdery mildew (the Sphaerotheca of strawberry Humuli), epidemic disease (Phytophthora nicotianae), anthracnose (Gromerella cingulata), breakdown of fruit disease (Pythium ultimum Trow var.ultimum)；

The net cake of tea sick (Exobasidium reticulatum), white star (Elsinoe leucospila), anthracnose (Colletotrichum theaesinensis), ring spot (Pestalotiopsis longiseta)；The rust of tobacco (Alternaria alternata (Tobacco pathotype)), powdery mildew (Erysiphe cichoracearum), anthrax Sick (Colletotrichum tabacum), epidemic disease (Phytophthora parasitica)；Damping-off (the Fusarium of cotton oxysporum)；

The sclerotiniose (Sclerotinia sclerotiorum) of sunflower；Scab (the Diplocarpon of rose Rosae), powdery mildew (Sphaerotheca pannosa), epidemic disease (Phytophthora megasperma), downy mildew (Peronospora sparsa)；Brown spot (Septoria chrysanthemi-indici), the white blister of chrysanthemum (Puccinia horiana), epidemic disease (Phytophthora cactorum)；Or

It is the brown spot (Rhizoctonia solani) of turfgrass, coin pinta (Sclerotinia homoeocarpa), curved Spore leaf blight (Curvularia geniculata), rust (Puccinia zoysiae), Helminthosporium leaf blight (Cochliobolus sp.), moire disease (Rhynchosporium secalis), damping-off (Gaeumannomyces Graminis), anthracnose (Colletotrichum graminicola), the rotten brown sclerotium oryzicola (Typhula of snow Incarnata rotten black small grain sclerotiniose (Typhula ishikariensis), snow big grain sclerotinia rot), are avenged (Sclerotinia borealis), collarium (Marasmius oreades etc.), rotten mildew (Pythium Aphanidermatum etc.), rice blast (Pyricularia oryzae), but be not limited to this.

[embodiment]

Hereinafter, enumerate preparation example and test example further specifically describes the present invention.But the present invention is not limited to preparation example And test example.It should be noted that all parts by weight of cooperation number of each composition described in following preparation example.

Compound (the I used in following preparation example and test example：Compound A (a-14), B (a-18) in organizing a) And C (a-20) is respectively compound number 1-866,1-929 in WO2005/070917 and 1-930 compound, respectively It is recorded in embodiment 114,177 and 178.Table 1 shows their chemical constitution.

[table 1]

Compound

R¹

R²

R³

R⁴

Xn

Ym

A(a-14)

Me

5-F

H

B(a-18)

Me

F

H

C(a-20)

Me

F

5-F

H

In addition, compound 2001 in the group b used in following preparation example and test example bactericidal properties compound~ 2009 compounds represented for logical formula (II),

R¹⁶~R¹⁹It is as shown in table 2 respectively.

[table 2]

The wettable powder of preparation example 1 (a1-1)

Will as any compound (10 parts) in composition I (group a) compound A, B and C, as composition II's (group b) Any compound (addition) of following records, Neogen powder (0.5 part), Carplex (0.5 part), Gohsenol (0.2 Part), sodalite (0.8 part) and H micro mists (making total amount be 100 parts, surplus is the material) be pulverized and mixed to obtain wettable powder (a1-1).

As composition II (group b) compound (addition) for maneb (88 parts of), Evil oxpoconazole fumarates (5 parts), gram Bacterium pellet (66 parts), Boscalid (25 parts), diethofencarb (6 parts), procymidone (25 portions of), Fu Evil bacterium (10 parts), thiophanate methyls (35 Part), fenhexamid (25 parts), fluazinam (10 parts), the octyl benzene sulfonate of biguanides three (20 parts), polyoxin compound (10 Part), isopropyl fixed (25 parts), pyrrole metsulfovax (5 parts), simeconazoles (5 parts), nitrile Fluoxastrobin (4 parts), the hydrochloride (1 of kasugarnycin one Part), valida (5 parts), tricyclazole (5 parts), ferimzone (5 parts), phthalide (5 parts), diclomezine (10 parts), flutolanil (12 Part), furan pyrazoles clever (5 parts), hexaconazole (1 part), RH-7592 (2.2 parts), Tebuconazole (10 parts), imines bacterium (10 parts), triazolone (5 parts), mepanipyrim (10 parts), acid amides azoles (7.5 parts), cyflufenamid (0.8 part), fenarimol (2 parts), fluorine bacterium azoles (3 parts), algae Bacterium phosphorus (80 parts), cymoxanil (10 parts), Kocide SD (27.6 parts), TPN (20 parts), the clever hydrochloride (80 parts) of hundred dimensions, cyazofamid (4.7 parts), metalaxyl (5 parts), Guardian (5 parts), Mancozeb (3.7 parts of), azolactones bacterium (5 parts), benzene metsulfovax (5 Part), metalaxyl M (5 parts), dimethomorph (10 parts) or compound 2001~2009 (5 parts).

The wettable powder of preparation example 2 (a2-1)

Will be as any compound (5 parts), the system as composition II (group b) in composition I (group a) compound A, B and C Any compound of the record of agent example 1, Neogen powder (0.5 part), Carplex (0.5 part), Gohsenol (0.2 part), sodium boiling Stone (0.8 part) and H micro mists (making total amount be 100 parts, surplus is the material) are pulverized and mixed to obtain wettable powder (a2-1).

The pulvis of preparation example 3 (b1-1)

Will as any compound (2 parts) in composition I (group a) compound A, B and C, as under composition II (group b) Any compound (addition) and clay (making total amount be 100 parts, surplus is the material) for stating record are equably pulverized and mixed, Obtain pulvis (b1-1).

Compound (addition) as composition II (group b) is captan (40 parts), Boscalid (25 parts), procymidone (25 parts), thiophanate methyl (35 parts), fluazinam (25 parts), the octyl benzene sulfonate of biguanides three (15 parts), polyoxin are compound Thing (25 parts), isopropyl fixed (25 parts), simeconazoles (10 parts), flutolanil (5 parts) or valida (0.3 part).

The pulvis of preparation example 4 (b2-1)

Will as any compound (10 parts) in composition I (group a) compound A, B and C, as composition II's (group b) Any compound of the record of preparation example 3, agglutinant (Driless A：0.3 part), clay (50 parts), calcium carbonate (make the total amount be 100 parts, surplus is the material) mixing, crushed with needle mill (pin mill), obtain pulvis (b2-1).

The suspending agent of preparation example 5 (c1)

Will be as any compound (5 in composition I (group a) compound A, B and C by the use of sand mill (Sand grinder) Part), any compound (addition) of following records as composition II (group b), propane diols (7 parts), sodium lignosulfonate (4 Part), dioctyl sodium sulfosuccinates sodium salt (2 parts) and water (making total amount be 100 parts, surplus is the material) case of wet attrition, obtain Suspending agent (c1).

Compound (addition) as composition II (group b) is nitrile Fluoxastrobin (10 parts), tricyclazole (10 parts), ferimzone (10 parts), phthalide (10 parts), flutolanil (3.5 parts), hexaconazole (10 parts), RH-7592 (11 parts), Tebuconazole (10 parts), procymidone (20 parts), cyazofamid (4 parts), TPN (20 parts), the octyl benzene sulfonate of biguanides three (5 parts) or sulphur (30 parts).

The emulsion of preparation example 6 (d1-1)

Will as any compound (10 parts) in composition I (group a) compound A, B and C, as composition II's (group b) Any compound (addition) of following records, hexamethylene (10 parts), Tween20 (surfactants：20 parts), dimethylbenzene (making total amount be 100 parts, surplus is the material) uniform dissolution mixing, obtains emulsion (d1-1).

Compound (addition) as composition II (group b) is Boscalid (20 parts), procymidone (20 parts), flutolanil (3.5 parts), RH-7592 (11 parts), Tebuconazole (10 parts), fluorine bacterium azoles (15 parts), TPN (20 parts), cycltebuconazole (10 parts), polyoxy Rhzomorph compound (5 parts), fluorine ether azoles (10 parts), triforine (15 parts), triazolone (25 parts of) Huo Difenoconazoles (25 parts).

The granule of preparation example 7 (e1-1)

Will as any compound (5 parts) in composition I (group a) compound A, B and C, as under composition II (group b) State any compound (addition), wetting agent (the NEOPELEX No.6F powder of record：0.5 part), adhesive (Amicol No.1：3 parts), talcum powder (15 parts), clay (make total amount be 100 parts, surplus be the material) mix and add water after, with extrusion system Grain machine is molded.Whole grain is carried out after obtained article shaped is dried, obtains granule (e1-1).

Compound (addition) as composition II (group b) is Boscalid (25 parts), procymidone (25 parts of), Fu Evil bacterium (10 parts), fenhexamid (25 parts), the octyl benzene sulfonate of biguanides three (15 parts), pyrrole metsulfovax (10 parts), simeconazoles (10 parts), Nitrile Fluoxastrobin (10 parts), valida (2.5 parts), tricyclazole (10 parts), flutolanil (3.5 parts), furan pyrazoles clever (10 parts), penta azoles Alcohol (10 parts), metalaxyl (5 parts), Mancozeb (7 parts), double chlorine zarilamid (3 parts), fork phenalgin acid amides (10 parts), chlorine ring propionyl Amine (15 parts), probenazole (10 parts) or Isoprothiolane (5 parts).

The wettable powder of comparative formulations example 1 (a1-2)

Will as any compound (10 parts) in composition I (group a) compound A, B and C, Neogen powder (0.2 part), Carplex (0.2 part), Gohsenol (0.1 part), sodalite (1 part) and H micro mists (making total amount be 100 parts, surplus is the material) It is pulverized and mixed, obtains wettable powder (a1-2).

The wettable powder of comparative formulations example 2 (a2-2)

Will as any compound (5 parts) in composition I (group a) compound A, B and C, Neogen powder (0.2 part), Carplex (0.2 part), Gohsenol (0.1 part), sodalite (1 part) and H micro mists (making total amount be 100 parts, surplus is the material) It is pulverized and mixed, obtains wettable powder (a2-2).

The pulvis of comparative formulations example 3 (b1-2)

Will be as any compound (2 parts) in composition I (group a) compound A, B and C and clay (98 parts) equably powder Broken mixing, obtain pulvis (b1-2).

The pulvis of comparative formulations example 4 (b2-2)

Will be as any compound (10 parts), agglutinant (Driless A in composition I (group a) compound A, B and C： 0.3 part), clay (50 parts), calcium carbonate (make total amount be 100 parts, surplus be the material) mix, crushed, obtained with needle mill To pulvis (b2-2).

The suspending agent of comparative formulations example 5 (c1-1)

Will be as any compound (5 parts), propane diols (7 in composition I (group a) compound A, B and C by the use of sand mill Part), sodium lignosulfonate (4 parts), dioctyl sodium sulfosuccinates sodium salt (2 parts) and water (82 parts) case of wet attrition, obtain suspending agent (c1-1).

The emulsion of comparative formulations example 6 (d1-2)

Will be as any compound (10 parts), hexamethylene (10 parts), diformazan in composition I (group a) compound A, B and C Benzene (50 parts) and Tween20 (surfactants：It is 100 parts to make total amount, and surplus is the material) equably dissolving mixing, obtain breast Agent (d1-2).

The granule of comparative formulations example 7 (e1-2)

Any compound (5 parts), wetting agent (NEOPELEX in it will be used as composition I (group a) compound A, B and C No.6F powder：0.5 part), adhesive (Amicol No.1：3 parts), talcum powder (15 parts), clay (make total amount be 100 parts, surplus For the material) equably mix and add water after, be molded with extrusion granulator machine.Made after obtained article shaped is dried Grain, obtains granule (e1-2).

The graw mold of tomato preventing iron test of test example 1 (diethofencarb resistant bacterium)

In greenhouse, make the tomato (kind being planted in diameter 5cm plastic tub：Large-scale Fu Shou) grow to the 2nd~3 leaf Phase.The wettable powder prepared according to preparation example 1 and preparation example 2 is diluted to normal concentration with water, spread with spray gun, every 2 basin 10ml., will be by the conidium for ash arrhizus bacteria (diethofencarb resistant bacterium) preparation cultivated in advance on MY culture mediums after decoction is dry Suspension spray is inoculated with.After inoculation, basin is put into the moist chamber of artificial infection room (20~22 DEG C), by taking out two days later, examined Examine preventive effect.In investigation, according to following occurring degree indexs, determine that lesion area accounts for the ratio of the whole leaflet of tomato.Separately Outside, the valency of preventing and kill off is calculated by the average onset degree of each treatment region using following calculating formulas.It is it should be noted that as a comparison, right The wettable powder prepared according to comparative formulations example 1 and comparative formulations example 2 is also tested according to the same manner, and is investigated and prevented and kill off Effect.Spread result of the test and the theoretical value based on Colby formulas is shown in table 3.

The index of occurring degree

It should be noted that using each treatment region and the average value in untreated area as occurring degree.

Valency is prevented and kill off to be calculated by following formula.

Prevent and kill off valency=(the morbidity leaflet rate in morbidity leaflet rate/untreated area of 1- treatment regions) × 100

It should be noted that Colby formulas are X=P+Q-P × Q/100, herein, X is the theoretical value for valency of preventing and kill off, and P is independent Prevent and kill off valency when spreading certain medicine, Q be by and medicine mixing spread when prevent and kill off valency.

[table 3-1]

[table 3-2]

From the result of above-mentioned table 3, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, tomato (kind：Large-scale Fu Shou) Upper discovery symptom of chemical damage.

The rice blast prophylactic tria of test example 2

In greenhouse, make the rice (kind being planted in diameter 5cm plastic tub：Good fortune wind) grew to for 3~4 leaf phases.Press Spread according to the mode same with test example 1, after spreading 3 days, by the Pyricularia oryzae by being cultivated in advance on oat medium The conidial suspension spray inoculation of preparation.After inoculation, basin is put into the moist chamber of artificial infection room (20~23 DEG C), second Its taking-up moves to greenhouse.Inoculation investigated preventive effect after 7 days.In investigation, determined according to the identical index of test example 1 Lesion area accounts for the ratio of every 1 leaf of rice, prevents and kill off valency and the theoretical value based on Colby formulas similarly calculates.The results are shown in table 4。

[table 4-1]

[table 4-2]

From the result of above-mentioned table 4, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, rice (kind：Good fortune wind) on send out Existing symptom of chemical damage.

The rice blast therapeutic test of test example 3

In greenhouse, make the rice (kind being planted in diameter 5cm plastic tub：Good fortune wind) grew to for 3~4 leaf phases.Will The conidial suspension spray inoculation prepared by the Pyricularia oryzae cultivated in advance on oat medium.After inoculation, basin is put In the moist chamber for entering artificial infection room (20~23 DEG C), take out within second day, spread according to the identical mode of test example 1.Medicine After liquid is dry, greenhouse is moved to, after spreading 7 days, investigates preventive effect.In investigation, scab is determined according to the identical index of test example 1 Area accounts for the ratio of every 1 leaf of rice, prevents and kill off valency and the theoretical value based on Colby formulas similarly calculates.The results are shown in table 5.

[table 5]

From the result of above-mentioned table 5, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, rice (kind：Good fortune wind) on send out Existing symptom of chemical damage.

The powdery mildew of cucumber prophylactic tria of test example 4

In greenhouse, make the cucumber (kind being planted in diameter 5cm plastic tub：Phase mould half is white) grow to 3~5 leaves Phase.Spread according to the mode same with test example 1, after spreading 3 days, cucumber powdery mildew's pathogen is inoculated on blade face.Inoculation Afterwards, constant temperature greenhouse (20~25 DEG C) is moved to, is inoculated with after 7 days, investigates preventive effect.In investigation, according to identical with test example 1 Index determine that lesion area accounts for the ratio of every 1 leaf of cucumber, prevent and kill off valency and the theoretical value based on Colby formulas similarly calculate.Its As a result it is shown in table 6.

[table 6-1]

[table 6-2]

From the result of above-mentioned table 6, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, cucumber (kind：Phase mould half is white) Upper discovery symptom of chemical damage.

The powdery mildew of cucumber therapeutic test of test example 5

In greenhouse, make the cucumber (kind being planted in diameter 5cm plastic tub：Phase mould half is white) grow to 3~5 leaves Phase.Cucumber powdery mildew's pathogen is inoculated on blade face, moves it to constant temperature greenhouse (20~25 DEG C).Inoculation two days later, according to examination The same mode of example 1 is tested to be spread.After decoction is dry, constant temperature greenhouse is moved to, is inoculated with after 7 days, investigate preventive effect.Investigate In, determine that lesion area accounts for the ratio of every 1 leaf of cucumber according to the identical index of test example 1, prevent and kill off valency and based on Colby formulas Theoretical value similarly calculates.The results are shown in table 7.

[table 7-1]

[table 7-2]

From the result of above-mentioned table 7, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, cucumber (kind：Phase mould half is white) Upper discovery symptom of chemical damage.

The tomato blight prophylactic tria of test example 6

In greenhouse, make the tomato (kind being planted in diameter 5cm plastic tub：Large-scale Fu Shou) grow to the 2nd~3 leaf Phase.Spread according to the mode same with test example 1, after decoction is dry, move to greenhouse.After spreading 3 days, spray inoculation tomato epidemic disease Germ (zoospore+zoosporangium) suspension.After inoculation, basin is put into the moist chamber of artificial infection room (20~22 DEG C), Greenhouse is moved within second day, after being inoculated with 7 days, investigates preventive effect.Determine that lesion area accounts for kind according to the identical index of test example 1 The ratio of every 1 leaf of eggplant, prevents and kill off valency and the theoretical value based on Colby formulas similarly calculates.The results are shown in table 8.

[table 8-1]

[table 8-2]

From the result of above-mentioned table 8, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, tomato (kind：Large-scale Fu Shou) Upper discovery symptom of chemical damage.

The tomato blight therapeutic test of test example 7

In greenhouse, make the tomato (kind being planted in diameter 5cm plastic tub：Large-scale Fu Shou) grow to the 2nd~3 leaf Phase.Inoculating tomato epidemic disease bacterium (zoospore+zoosporangium) suspension, basin is put into the wet of artificial infection room (20~22 DEG C) Interior, take out within second day, spread according to the mode same with test example 1.After decoction is dry, greenhouse is moved to, after being inoculated with 7 days, Investigate preventive effect.Determine that lesion area accounts for the ratio of every 1 leaf of tomato according to the identical index of test example 1, prevent and kill off valency and base Similarly calculated in the theoretical value of Colby formulas.The results are shown in table 9.

[table 9-1]

[table 9-2]

From the result of above-mentioned table 9, and during with compound A, B or C and the compound of b groups, synergy is can obtain, need It is noted that even and if with compound A, B or C and the compound of b groups, also not in plant, tomato (kind：Large-scale Fu Shou) Upper discovery symptom of chemical damage.

The cucumber downy mildew prophylactic tria of test example 8

In greenhouse, make the cucumber (kind being planted in diameter 5cm plastic tub：Phase mould half is white) grow to 3~5 leaves Phase.Spread according to the mode same with test example 1, after decoction is dry, move to greenhouse.After spreading 3 days, cucumber downy mildew is inoculated with Bacterium.After inoculation, basin is put into the moist chamber of artificial infection room (20~25 DEG C), moves within second day greenhouse, after being inoculated with 7 days, investigated Preventive effect.Determine that lesion area accounts for the ratio of every 1 leaf of cucumber according to the identical index of test example 1, prevent and kill off valency and be based on The theoretical value of Colby formulas similarly calculates.The results are shown in table 10.

[table 10-1]

[table 10-2]

From the result of above-mentioned table 10, and during with compound A, B or C and the compound of b groups, synergy is can obtain, It should be noted that even and if with compound A, B or C and the compound of b groups, also not in plant, cucumber (kind：Phase mould half Symptom of chemical damage is found in vain).

The cucumber downy mildew therapeutic test of test example 9

In greenhouse, make the cucumber (kind being planted in diameter 5cm plastic tub：Phase mould half is white) grow to 3~5 leaves Phase.Be inoculated with bacterium of downy mildew of cucumber, basin is put into the moist chamber of artificial infection room (20~22 DEG C), second day take out, according to examination The same mode of example 1 is tested to be spread.After decoction is dry, greenhouse is moved to, after being inoculated with 7 days, investigates preventive effect.According to test example 1 identical index determines that lesion area accounts for the ratio of every 1 leaf of cucumber, prevents and kill off valency and the theoretical value based on Colby formulas is similarly calculated Go out.The results are shown in table 11.

[table 11-1]

[table 11-2]

From the result of above-mentioned table 11, and during with compound A, B or C and the compound of b groups, synergy is can obtain, It should be noted that even and if with compound A, B or C and the compound of b groups, also not in plant, cucumber (kind：Phase mould half Symptom of chemical damage is found in vain).

Industrial applicability

The plant disease control composition of the present invention is to the various plants pathogen including drug-resistant bacterium (for example, rice Rice blast (Pyricularia oryzae), tomato, the gray mold (Botrytis cinerea) etc. of cucumber and Kidney bean) have it is more Kind disease spectrum, the excellent preventive effect (preventive effect of collaboration) that can not be expected by separate constituent is shown, in addition, even if right In the resistant bacterium to existing medicine, high plant disease control effect is displayed that, and does not find to produce poisoning to plant, thus It can be used as excellent plant disease control agent.

Claims

A kind of 1. plant disease control composition, it is characterised in that active ingredient is used as containing following (a) and (b),

(a) following (a-14), (a-18) and at least one kind of quinoline compound or its salt (group a) in (a-20) are selected from,

(a-14) 3- (tetramethyl -3, the 4- dihydro-isoquinoline -1- bases of 5- fluoro- 3,3,4,4-) quinoline,

(a-18) 3- (4,4- bis- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline and

(a-20) 3- (4,4,5- tri- fluoro- 3,3- dimethyl -3,4- dihydro-isoquinoline -1- bases) quinoline,

(b) following bactericidal properties compounds (group b),

(b-15-2) thiophanate methyl,

The mixing ratio of described group of a quinoline compound and described group of b bactericidal properties compound, using weight ratio meter as following ratios： Relative to group a quinoline compound 1, the bactericidal properties compound for organizing b is 0.1~100, also, the mixing ratio cooperates with for display The mixing ratio of effect.
A kind of 2. the method for control for preventing and kill off plant disease, using the plant disease control composition described in claim 1.
3. a kind of method for preventing and kill off plant disease, the quinoline compound containing the group a described in claim 1 is administered simultaneously and makees Plant disease control composition for active ingredient and contain the bactericidal properties compound of group b described in claim 1 as effective The plant disease control composition of composition, or the compound for containing the group a described in claim 1 is being applied as active ingredient Plant disease control composition or contain plant of the bactericidal properties compound of group b described in claim 1 as active ingredient Disease prevent and kill off either one in composition after, using the composition of the opposing party,

The mixing ratio of described group of a quinoline compound and described group of b bactericidal properties compound, using weight ratio meter as following ratios： Relative to group a quinoline compound 1, the bactericidal properties compound for organizing b is 0.1~100, also, the mixing ratio cooperates with for display The mixing ratio of effect.