CN105232082A - Contrast imaging method, contrast imaging device and ultrasonic equipment - Google Patents

Contrast imaging method, contrast imaging device and ultrasonic equipment Download PDF

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Publication number
CN105232082A
CN105232082A CN201510670482.6A CN201510670482A CN105232082A CN 105232082 A CN105232082 A CN 105232082A CN 201510670482 A CN201510670482 A CN 201510670482A CN 105232082 A CN105232082 A CN 105232082A
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time
real
characteristic
contrastographic picture
contrast imaging
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CN201510670482.6A
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Chinese (zh)
Inventor
朱建武
冯乃章
周文平
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Sonoscape Medical Corp
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Sonoscape Medical Corp
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Priority to CN201510670482.6A priority Critical patent/CN105232082A/en
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Abstract

The invention provides a contrast imaging method. The contrast imaging method includes: presetting contrast imaging characteristics and a corresponding pathological diagnosis and analysis database; under a contrast imaging mode, when contrast agents are infused, acquiring real-time contrast images and acquiring real-time contrast image characteristics by analyzing the real-time contrast images in real time; indexing the database and acquiring corresponding pathological diagnosis and analysis of the real-time contrast image characteristics prestored in the database, so that pathological diagnosis and analysis of the real-time contrast images are acquired in real time. The invention further provides a contrast imaging device and ultrasonic equipment. The contrast imaging method, the contrast imaging device and the ultrasonic equipment in the technical scheme are used for solving the problem that diagnosis and analysis results cannot be obtained in real time while contrast imaging is performed in the prior art.

Description

A kind of contrast imaging method, device and ultrasonic device thereof
Technical field
The application relates to contrast imaging technical field, more particularly, relates to a kind of contrast imaging method, device and ultrasonic device thereof.
Background technology
Angiographic function is in the past all carry out under off-line data, contrast imaging time-activity curve and relevant perfusion parameters cannot be shown under real-time scanning, the quantitative information obtaining focus that cannot be real-time, simultaneously after completing contrast imaging, needs manual to fill in diagnosing patient report.
Summary of the invention
In view of this, the application provides a kind of contrast imaging method, device and ultrasonic device thereof, for solving in prior art, can not obtain the problem of diagnostic analysis result while contrast imaging in real time.
To achieve these goals, the existing scheme proposed is as follows:
The invention provides a kind of contrast imaging method, described method comprises the steps:
Set up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis in advance;
Under contrast imaging pattern, while perfusion contrast agent, obtain real-time contrastographic picture, and by the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
The present invention also provides a kind of contrast imaging method, and described method comprises the steps:
Set up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis data in advance;
Under contrast imaging pattern, startup analysis unit while perfusion contrast agent;
Obtain real-time contrastographic picture, and by the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
The present invention also provides a kind of contrast imaging device, and described device comprises: memory element, the first control unit, analytic unit, the second control unit;
Described memory element, for storing the data base of characteristic and the corresponding Pathologic Diagnosis setting up contrast imaging in advance;
Described first control unit, for obtaining the real-time contrastographic picture in contrast agent perfusion process;
Described analytic unit, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Described second control unit, for data base described in index, obtain the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
The present invention also provides a kind of contrast imaging device, and described device comprises: memory element, analysis start unit, the first control unit, analytic unit, the second control unit;
Described memory element, for storing the data base of characteristic and the corresponding Pathologic Diagnosis data setting up contrast imaging in advance;
Described analysis start unit, for starting described analytic unit.
Described first control unit, for obtaining the real-time contrastographic picture in contrast agent perfusion process.
Described analytic unit, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Described second control unit, for data base described in index, obtain the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
The present invention also provides a kind of ultrasonic device, and described equipment has any one device as above.
Technical scheme tool of the present invention is adopted to have the following advantages:
1, the present invention is by setting up the characteristic of contrastographic picture and the data base of corresponding analysis in advance, by the real-time characteristic real-time contrastographic picture analysis being drawn to contrastographic picture, and the contrastographic picture characteristic of having preserved in this characteristic and data base matched, thus automatically can obtain the Pathologic Diagnosis corresponding with this characteristic in real time simultaneously.
2, the method for the present embodiment is when carrying out real-time analysis to the real-time contrastographic picture obtained, and after needing startup analysis unit, just can carry out real-time analysis.Therefore the right selected with doctor is given, when doctor needs to analyze contrastographic picture in real time, then select startup analysis unit while perfusion, if and do not need to start the function of real-time analysis, then not startup analysis unit while perfusion, then system conventionally, only carries out contrast imaging and do not provide analysis.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only embodiments of the invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to the accompanying drawing provided.
The schematic flow sheet of the contrast imaging method that Fig. 1 provides for a kind of embodiment of the application;
Fig. 2 for the schematic flow sheet of contrast imaging method that provides of the another kind of embodiment of application;
The contrast imaging apparatus structure schematic diagram that Fig. 3 provides for a kind of embodiment of the application;
The contrast imaging apparatus structure schematic diagram that Fig. 4 provides for the another kind of embodiment of the application.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment one,
As shown in Figure 1, for solving the problem, the present embodiment proposes a kind of contrast imaging method, at contrast imaging simultaneously, can provide real-time contrast imaging analytic function.Described method comprises the steps:
S101, sets up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis data in advance.
Analyze according to the case after the multiple contrast imagings obtained in advance, obtain the characteristic of contrast perfusion imaging corresponding to different classes of case, thus set up the contrast imaging characteristic contrast perfusion pathological data storehouse corresponding with between case, data base is preserved in the memory unit.
It should be noted that, in some cases, contrast perfusion imaging characteristic can an only corresponding pathological analysis; And in some cases one cause Perfusion Imaging characteristic also can simultaneously corresponding multiple alternative analysis, select for doctor.
S102, under contrast imaging pattern, while perfusion contrast agent, obtains real-time contrastographic picture, and by the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture.
Under contrast imaging pattern, choose focal area, concrete available closed ROI mark; Start to inject contrast agent toward patient, while the real-time contrast perfusion ultrasonoscopy of acquisition, by the analysis of parser module to described real-time contrast perfusion ultrasonoscopy, obtain the characteristic of real-time contrast perfusion ultrasonoscopy.
S103, data base described in index, obtains and prestores the Pathologic Diagnosis corresponding to characteristic matched with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
After the characteristic obtaining real-time contrastographic picture in real time, at once index data base, search the characteristic of the contrastographic picture matched with the characteristic of this real-time contrastographic picture in data base, once find the characteristic of corresponding contrastographic picture, the analysis of at least one case corresponding of the characteristic due to each contrastographic picture in data base, therefore can at once obtain corresponding Pathologic Diagnosis, these Pathologic Diagnosis data are the real-time contrastographic picture analysis of real-time contrastographic picture.
The present invention is by setting up the characteristic of contrastographic picture and the data base of corresponding Pathologic Diagnosis in advance, by the real-time characteristic real-time contrastographic picture analysis being drawn to contrastographic picture, and the contrastographic picture characteristic of having preserved in this characteristic and data base matched, thus automatically can obtain the Pathologic Diagnosis corresponding with this characteristic in real time simultaneously.
In certain embodiments, in described step S102, the step of the characteristic of the real-time contrastographic picture of described acquisition being carried out to display in real time can also be comprised after the characteristic obtaining described real-time contrastographic picture.
In certain embodiments, described contrast perfusion imaging characteristic can comprise; Time-activity curve, perfusion parameters (such as: contrast agent time of advent, time to peak, peak strength etc.).
Described characteristic can comprise time-activity curve, perfusion parameters or both combine.
Time-activity curve computational methods have a variety of, a kind of the most frequently used method is image intensity value in each frame contrastographic picture of statistics ROI frame, the relative time that the intensity curve value obtained and contrast agent inject human body is mapped, just obtain time-activity curve, described method belongs to prior art, does not repeat them here.
Contrast imaging perfusion parameters is calculated by corresponding computational methods after obtaining time-activity curve, only has after first having calculated time-activity curve, just can calculate these parameters.The application is the contrast imaging analysis in real-time scanning situation, namely calculating strength curve under real-time scanning state, when needs calculate parameter, first must stop the state of real-time calculated curve, first obtain a curve calculated, just can carry out parameter calculating.
Often kind of pathological analysis has corresponding time-activity curve or perfusion parameters, corresponding time-activity curve or perfusion parameters are first stored into data base, then the real-time time intensity curve obtained or perfusion parameters are mated with the time-activity curve stored in system or perfusion parameters, then will mate the curve that obtains or Pathologic Diagnosis data corresponding to parameter recall from storage device.
Further, when described characteristic comprises described time-activity curve, the similarity of the time-activity curve preserved in real-time time intensity curve and data base can be obtained by algorithm.Described algorithm can comprise: be first normalized by Real-time intensity curve, then according to the time span of current collection real time data, calculate the time-activity curve data length of corresponding time span in data base, the similarity degree that correlation coefficient determines curve is calculated by the method for variance or Pearson's correlation coefficient (PearsonCorrelationCoefficient), described method belongs to prior art, does not repeat them here.
Set up contrast perfusion pathological analysis data base in advance, by analyzing the contrast perfusion characteristic obtained, the corresponding diagnostic result of automatic selection, when the perfusion situation that there is multiple pathological characters is consistent, provides plurality of optional result, select for doctor, doctor also can select the pattern of the case of oneself editing, and doctor generates diagnosis report after completing corresponding selection or report editor automatically, improve the diagnosis efficiency of doctor, provide doctor the case template oneself defined to be saved in system simultaneously.
In certain embodiments, also comprise after described S103: described analysis be directly sent to display unit display or export.
Directly be sent on display by this analysis result and show, or directly printed by printer or output to external network or external connection display equipment.
In certain embodiments, also comprise after described S103: described analysis is edited, generate patient diagnosis report.
Described editor comprises two kinds of situations, and when the contrast characteristics situation that there is multiple pathological characters is consistent, can get multiple alternative analysis result and select for doctor, doctor can select as the case may be; Doctor also can select the pattern of the case of oneself editing, and after completing corresponding selection or report editor, automatically generates diagnosis report, improves the diagnosis efficiency of doctor, provide doctor the case template oneself defined to be remained in system simultaneously.
Embodiment two,
As shown in Figure 2, in another kind of embodiment of the present invention, provide another kind of contrast imaging method, described method comprises the steps:
S201, sets up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis in advance.
S202, under contrast imaging pattern, startup analysis unit while perfusion contrast agent.
While injection contrast agent, start real-time analysis unit, namely the hand-held probe of operator can obtain the real-time analysis of contrastographic picture in real time in ultrasonic scan process.
Described startup, can be realized by button or touch control operation.
S203, obtains real-time contrastographic picture, and by the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
S204, data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the analysis of real-time contrastographic picture described in Real-time Obtaining.
The method of the present embodiment, when carrying out real-time analysis to the real-time contrastographic picture obtained, after needing startup analysis unit, just can carry out real-time analysis.Therefore the right selected with doctor is given, when doctor needs to analyze contrastographic picture in real time, then select startup analysis unit while perfusion, if and do not need to start the function of real-time analysis, then not startup analysis unit while perfusion, then system conventionally, only carries out contrast imaging and do not provide analysis.Other parts step method in the present embodiment and detailed content identical with the detailed description in embodiment one, specifically see specific embodiment one, can not repeat them here.
Embodiment three,
As shown in Figure 3, another kind of embodiment of the present invention also provides a kind of contrast imaging device 300, and described device comprises: memory element 301, first control unit 302, analytic unit 303, second control unit 304;
Described memory element 301, for storing the data base of characteristic and the corresponding Pathologic Diagnosis setting up contrast imaging in advance;
Described first control unit 302, for obtaining the real-time contrastographic picture in contrast agent perfusion process;
Described analytic unit 303, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Described second control unit 304, for data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the analysis of real-time contrastographic picture described in Real-time Obtaining.
The work process of described device, see specific embodiment one, does not repeat them here.
In certain embodiments, described device also comprises: display unit 305, and the characteristic for the real-time contrastographic picture to described acquisition shows in real time or shows the analysis of the described real-time contrastographic picture of described acquisition.
In certain embodiments, described device also comprises: the 3rd control unit 306, for editing the analysis of described real-time contrastographic picture, to generate patient diagnosis report.
Embodiment four,
As described in Figure 4, also provide a kind of contrast imaging device in another kind of embodiment of the present invention, described device comprises: memory element 401, startup analysis unit 402, first control unit 403, analytic unit 404, second control unit 405;
Described memory element 401, for storing the data base of characteristic and the corresponding Pathologic Diagnosis setting up contrast imaging in advance.
Described startup analysis unit 402, for starting described analytic unit.Described startup analysis unit can be a timer, by clicking the button on control panel or the touching control on touch screen, triggered timer, thus starts described analytic unit.
Described first control unit 403, for obtaining the real-time contrastographic picture in contrast agent perfusion process.
Described analytic unit 404, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture.
Described second control unit 405, for data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the analysis of real-time contrastographic picture described in Real-time Obtaining.
In certain embodiments, described device also comprises: display unit 406, and the characteristic for the real-time contrastographic picture to described acquisition shows in real time or shows the analysis of the described real-time contrastographic picture of described acquisition.
In certain embodiments, described device also comprises: the 3rd control unit 407, for editing the analysis of described real-time contrastographic picture, to generate patient diagnosis report.
The work process of described device, see specific embodiment one, two, does not repeat them here.
Embodiment five,
The another kind of embodiment of the present invention also provides a kind of ultrasonic device, and described equipment comprises the device described in any embodiment three, four.
It should be noted that, for aforesaid each embodiment of the method, in order to simple description, therefore it is all expressed as the combination of a series of actions, but those skilled in the art should know, the present invention is not by the restriction of the order of described action, because according to the present invention, some step can adopt other order or carry out simultaneously.Secondly, those skilled in the art also should know, the embodiment described in description all belongs to preferred embodiment, and involved action and module might not be that the present invention is necessary.
Finally, also it should be noted that, the all or part of step that it will be appreciated by those skilled in the art that in the various methods of above-described embodiment can carry out by program the hardware that instruction is correlated with to have come, and this program can be stored in a computer-readable memory element.Memory element described in all embodiments of the present invention comprises: read only memory, random access memory, disk or etc.
In this article, such as term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thus make to comprise the process of a series of key element, method, article or equipment and not only comprise those key elements, but also comprise other key elements clearly do not listed, or also comprise by the intrinsic key element of this process, method, article or equipment.When not more restrictions, the key element limited by statement " comprising ... ", and be not precluded within process, method, article or the equipment comprising described key element and also there is other identical element.
In this description, each embodiment adopts the mode of going forward one by one to describe, and what each embodiment stressed is the difference with other embodiments, between each embodiment identical similar portion mutually see.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.

Claims (15)

1. a contrast imaging method, is characterized in that, described method comprises the steps:
Set up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis in advance;
Under contrast imaging pattern, while perfusion contrast agent, obtain real-time contrastographic picture,
By the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
2. method according to claim 1, is characterized in that, comprises and show in real time the characteristic of described real-time contrastographic picture after the characteristic of the described real-time contrastographic picture of described acquisition.
3. method according to claim 1 and 2, is characterized in that, also comprises: show described Pathologic Diagnosis after the Pathologic Diagnosis of the real-time contrastographic picture of described acquisition.
4. method according to claim 1 and 2, is characterized in that, also comprises: edit described Pathologic Diagnosis after the Pathologic Diagnosis of the real-time contrastographic picture of described acquisition, generates patient diagnosis report.
5. the method according to claim 1 or 2 or 3 or 4, it is characterized in that, described characteristic comprises: time-activity curve.
6. the method according to claim 1 or 2 or 3 or 4, it is characterized in that, described characteristic comprises: perfusion parameters.
7. a contrast imaging method, is characterized in that, described method comprises the steps:
Set up the characteristic of contrast imaging and the data base of corresponding Pathologic Diagnosis in advance;
Under contrast imaging pattern, startup analysis unit while perfusion contrast agent;
Obtain real-time contrastographic picture, and by the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Data base described in index, obtains the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
8. method according to claim 7, is characterized in that, comprises and show in real time the characteristic of described real-time contrastographic picture after the characteristic of the described real-time contrastographic picture of described acquisition.
9. the method according to claim 7 or 8, is characterized in that, also comprises: show described Pathologic Diagnosis after described acquisition Pathologic Diagnosis.
10. the method according to claim 7 or 8, is characterized in that, also comprises: edit described Pathologic Diagnosis after described acquisition Pathologic Diagnosis, generates patient diagnosis report.
11. methods according to claim 7 or 8 or 9 or 10, it is characterized in that, described characteristic comprises: time-activity curve.
12. methods according to claim 7 or 8 or 9 or 10, it is characterized in that, described characteristic comprises: perfusion parameters.
13. 1 kinds of contrast imaging devices, is characterized in that, described device comprises: memory element, the first control unit, analytic unit, the second control unit;
Described memory element, for storing the data base of characteristic and the corresponding Pathologic Diagnosis setting up contrast imaging in advance;
Described first control unit, for obtaining the real-time contrastographic picture in contrast agent perfusion process;
Described analytic unit, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Described second control unit, for data base described in index, obtain the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
14. 1 kinds of contrast imaging devices, is characterized in that, described device comprises: memory element, analysis start unit, the first control unit, analytic unit, the second control unit;
Described memory element, for storing the data base of characteristic and the corresponding Pathologic Diagnosis setting up contrast imaging in advance;
Described analysis start unit, for starting described analytic unit.
Described first control unit, for obtaining the real-time contrastographic picture in contrast agent perfusion process;
Described analytic unit, for the real-time analysis to described real-time contrastographic picture to obtain the characteristic of described real-time contrastographic picture;
Described second control unit, for data base described in index, obtain the Pathologic Diagnosis prestored corresponding to characteristic corresponding with the characteristic of described real-time contrastographic picture in the database, thus the Pathologic Diagnosis of real-time contrastographic picture described in Real-time Obtaining.
15. 1 kinds of ultrasonic devices, is characterized in that, described equipment has the device as described in claim 13-14 any one.
CN201510670482.6A 2015-10-16 2015-10-16 Contrast imaging method, contrast imaging device and ultrasonic equipment Pending CN105232082A (en)

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