CN105213062A - A kind of Mus caudal vertebra pressue device - Google Patents
A kind of Mus caudal vertebra pressue device Download PDFInfo
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- CN105213062A CN105213062A CN201510560998.5A CN201510560998A CN105213062A CN 105213062 A CN105213062 A CN 105213062A CN 201510560998 A CN201510560998 A CN 201510560998A CN 105213062 A CN105213062 A CN 105213062A
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- stud
- groove
- bulging
- alveolus
- bar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
Abstract
The invention discloses a kind of Mus caudal vertebra pressue device, by fixture, bulging is configured to outward, fixture has two and structure is identical end to end, form by left and right two parts, left part body layer walks crosswise district up and down respectively a groove, alveolus in it and the alveolus phase hasp on right part block tongue sheet, thus make the rubber layer and the Mus tail close contact that are positioned at body layer inner surface, by pressing down the lock that links closely on block tongue sheet, it is made to enter hole of linking closely, the interalveolar hasp of further increase, thus whole fixture contacts tightr with Mus tail, bulging outrigger can insert in the bulging groove of fixture side, by the distance between adjusting head side foot-stand upper stud groove bar and nest shape connecting rod, exerting pressure to one-sided or whole intervertebral disc and cartilage endplate can be realized, present invention achieves and multi-faceted modeling is carried out to Mus caudal vertebra, modeling is made to have higher comparability, and it is simple to operate, better can be applied to the zooscopy of this area.
Description
Technical field
The present invention relates to a kind of Mus caudal vertebra pressue device.
Background technology
Intervertebral disc degeneration is the main cause of the spinal column such as cervical spondylosis, prolapse of lumbar intervertebral disc degenerative disease, can cause the symptoms such as neck shoulder, lumbago and skelalgia, need operative treatment time serious.Cause the cause of disease of intervertebral disc degeneration complicated, relate to the many aspects such as aging, inflammation, dysimmunity, mechanics factor, but definite mechanism it be unclear that, in order to seek effective treatment measure and definite Etiologic Mechanism, zoopery is very important process.
Zoopery is the various main path delaying, suppress, reverse the Therapeutic Method of intervertebral disc degeneration of research, contributes to the effectiveness and reliability of method of proof.At present, rodent intervertebral disc degeneration model is suggested, wherein with the model that rat disc repairing research is ideal, not only its intervertebral disc composition and the mankind similar, and its cost is low, be convenient to look after, the position of tail intervertebral disc of rat is easy to operation simultaneously, and the mode at present usually through acupuncture tail intervertebral disc induces intervertebral disc degeneration.But while the intervertebral disc degeneration that this kind of mode is induced comprises vertebral pulp, fibrous ring and cartilage endplate three more or regression in succession, and easily cause spinal disc interior structural damage, for the regression of a certain intervertebral disc structure of research, this kind of mode still has some deficits.
For the regression of cartilage endplate, especially corresponding Modic changes, think that it is the micro-fracture due to cartilage endplate at first at present, under the External Force Acting continued, there is inflammatory cell hypertrophy in fracture, and edema is oozed out in local, then blood vessel hyperplasia, granulation is formed, lipidosis, the serial pathophysiological process such as New bone formation.Therefore, how a kind of modeling device is provided, can comparatively simply and constantly improve in intervertebral disc and the pressure of cartilage endplate, simultaneously again can in one-sided raising intervertebral disc and the pressure of cartilage endplate, thus form tail intervertebral disc of rat cartilage endplate regression model, making experiment have higher comparability, is those skilled in the art's technical issues that need to address.
Summary of the invention
In order to improve simply and constantly in intervertebral disc and the pressure of cartilage endplate, simultaneously again can in one-sided raising intervertebral disc and the pressure of cartilage endplate, therefore we devise this Mus caudal vertebra pressue device.
The present invention is achieved by the following technical solutions:
1, the present invention relates to a kind of Mus caudal vertebra pressue device, be configured to by outside fixture, bulging, described fixture has two end to end, and the same side of two described fixtures has a bulging groove respectively, described bulging groove respectively with the foot rest phase sleeve of the both sides end to end of described bulging outrigger.
2, described fixture, two structures are identical end to end for it, and by left and right sides two parts composition, both are connected by the mutual hasp of inside and outside alveolus.
3, described fixture left part, be made up of body layer and rubber layer, overall in one " C " shape structure, described body layer is made up of hard material, the outer surface central authorities that upper and lower walks crosswise district have the groove that links closely respectively, link closely hole in described groove inside of linking closely, described upper and lower walks crosswise district's center of inside a groove respectively, opening is towards right side, the groove in district is walked crosswise in described top, lower surface in it is distributed with interior alveolus, oblique left side, described upper interior alveolus and the upper outside alveolus phase hasp on the top block tongue sheet of described fixture right part, the groove in district is walked crosswise in described below, upper surface in it is distributed with lower interior alveolus, oblique left side, described lower interior alveolus and the lower outside alveolus phase hasp on the below block tongue sheet of described fixture right part, on the left of described body layer, there are a bulging groove in central authorities of stringer district, be seamless sleeve with the foot rest of described bulging outrigger, described rubber layer is fixed on the inner surface of described body layer, on the right side of it, central authorities are a semicircular structure.
4, described fixture right part, be made up of body layer and rubber layer, overall in an inverted " C " shape structure, described body layer is made up of hard material, upper and lower walks crosswise the block tongue sheet that central authorities of district respectively have to stretch to the left, described block tongue sheet is made up of bendable material, the first half area distribution of the lower surface of described top block tongue sheet has upper outside alveolus, oblique right side, described upper outside alveolus and described upper interior alveolus phase hasp, the upper surface front center of described top block tongue sheet has a brood of shape structure, itself and the top chondritic of locking lower end that links closely is that ball-and-socket is connected, the first half area distribution of the upper surface of described below block tongue sheet has lower outside alveolus, oblique right side, described lower outside alveolus and described lower interior alveolus phase hasp, the lower surface front center of described below block tongue sheet has a brood of shape structure, itself and the below chondritic of locking lower end that links closely is that ball-and-socket is connected.
5, the described lock that links closely, there is upper and lower two, and structure is identical, by shank of the key, lock core forms, both are structure as a whole, described lock core lower end is chondritic, it is that ball-and-socket is connected with described nest shape structure, both are inseparable, and the described lock that links closely can rotate freely being parallel on described block tongue plate plane, described lock core there is a bar-shaped snap close, itself and the described mutual snap close in hole of linking closely, the length of described bar-shaped snap close is greater than the width of the described groove that links closely, and be less than the width in described hole of linking closely, described shank of the key is a club shaped structure, its central authorities are fixed on described lock core.
6, described bulging outrigger, by the foot rest of both sides and the bulging bar of central authorities form end to end, both are structure as a whole, described head side foot-stand, by casing string, stud groove bar, spherical stud, nest shape connecting rod, locking rod forms, described casing string and described stud groove bar are threaded, described stud groove bar and described spherical stud are threaded, described spherical stud is that ball-and-socket is connected with described nest shape connecting rod, described locking rod and described spherical stud and described nest shape connecting rod phase sleeve, described casing string, its one end is for entering groove post, be seamless sleeve with described bulging groove, the other end is interior swivel nut pipe, be threaded with the stud end of described stud groove bar, described stud groove bar, its one end is stud end, be threaded with swivel nut pipe in described casing string, there are a groove in other end central authorities, female thread structure is distributed with in it, the stud end of described female thread structure and described spherical stud is threaded, described spherical stud, its one end is stud end, be threaded with described female thread structure, the stud end of described spherical stud has a chromonema, it is for being partly colored the line of screw thread, and with stud longer axis parallel, described chromonemal extended line is by the pore space structure on described spherical stud, the other end of described spherical stud is porose chondritic, be that ball-and-socket is connected with the porose nest shape structure of described nest shape connecting rod, described porose chondritic there is a pore space structure, itself and described locking rod phase sleeve, described nest shape connecting rod, one end is porose nest shape structure, it is that ball-and-socket is connected with described porose chondritic, it there is a pore space structure, with described locking rod phase sleeve, described porose nest shape structure there is an indicatrix, its extended line is by the pore space structure of described porose nest shape structure, the other end of described nest shape connecting rod is connected with the head end of described bulging bar, both are structure as a whole.
7, described bulging bar, it is connected with the foot rest end to end described in both sides at two ends end to end, both are structure as a whole, middle body is stud sleeve structure, described stud sleeve structure by interior swivel nut pipe and end to end two studs form, the hand of spiral of two described studs is contrary end to end, pitch and diameter identical, and be threaded with interior swivel nut pipe respectively, described interior swivel nut pipe, the hand of spiral at its inner surface two ends is end to end contrary, pitch and diameter identical, and to be threaded with the stud of homonymy respectively.
8, described tail side foot-stand, its one end and described bulging groove are seamless sleeve, and the other end is connected with the tail end of described bulging bar, and both are structure as a whole.
Accompanying drawing explanation
Fig. 1 Mus caudal vertebra pressue device side isometric view.
Fig. 2 fixture left part side isometric view.
Fig. 3 fixture right part side isometric view.
Fig. 4 head side foot-stand profile.
Walk crosswise side, district above Fig. 5 to see.
In figure: 1. body layer; 2. rubber layer; 3. link closely groove; 4. block tongue sheet above; 5. alveolus in going up; 6. upper outside alveolus; 7. bulging groove; 8. link closely lock; 9. semicircular structure; 10. block tongue sheet below; Alveolus in 11. times; 12. lower outside alveolus; 13. casing strings; 14. stud groove bars; 15. locking rods; 16. spherical studs; 17. tail side foot-stands; 18. bulging bars; 19. pore space structures; 20. nest shape connecting rods; 21. chromonema; 22. indicatrixs; 23. shank of the keys; 24. bar-shaped snap closes; 25. chondritics; 26. nest shape structures; 27. link closely hole; 28. grooves.
Detailed description of the invention 1
Get experimental mouse one, after being anaesthetized, lie on the back and be fixed on operating board, and its tail is fixed, choose the caudal vertebra sections of plan operation, the fixture of both sides is end to end individually fixed on corresponding caudal vertebra sections, alveolus 5 and the upper outside alveolus 6 on top block tongue sheet 4 hasp mutually in now going up, alveolus 11 and the lower outside alveolus 12 on below block tongue sheet 10 hasp mutually in lower, the lock 8 that links closely is positioned at the groove 3 that links closely, and the longer axis parallel of the major axis of bar-shaped snap close 24 and the groove 3 that links closely, the body layer 1 of the left and right sides is drawn close mutually, the rubber layer 2 of the left and right sides is drawn close and the semicircular structure 9 of both sides and Mus tail close contact mutually, then the shank of the key 23 linked closely on lock 8 that each fixture is upper and lower is pressed successively, along with chondritic 25 is with shape structure 26 of starting moving to press down, make upper and lower block tongue sheet lower curved in groove 28, until bar-shaped snap close 24 arrives hole 27 plane that links closely, then rotate the lock 8 that links closely and reach 90 °, bar-shaped snap close 24 is made to be positioned at hole 27 of linking closely, thus make whole fixture more firmly be fixed on Mus tail, before bulging outrigger is installed to fixture, in advance stud groove bar 14 and nest shape connecting rod 20 are maintained a certain distance, the operation of this process is first alignd with indicatrix 22 by chromonema 21, pore space structure 19 now on spherical stud 16 and the pore space structure 19 on nest shape connecting rod 20 are point-blank, then locking rod 15 is inserted in pore space structure 19, now rotate stud groove bar 14, until make stud groove bar 14 and nest shape connecting rod 20 reach target range, after this process terminates, the foot rest sleeve of the both sides end to end of bulging outrigger is entered in bulging groove 7, pressurize as needed offside intervertebral disc, then rotary sleeve tubing string 13, the length of a side foot-stand is made to be greater than tail side foot-stand 17, then Mus tail far-end is to lateral bend, now rotate the interior swivel nut pipe on bulging bar 18, bulging bar 18 is lengthened, thus increase the pressure of offside intervertebral disc and cartilage endplate further.
Detailed description of the invention 2
Get experimental mouse one, after being anaesthetized, lie on the back and be fixed on operating board, and its tail is fixed, choose the caudal vertebra sections of plan operation, the fixture of both sides is end to end individually fixed on corresponding caudal vertebra sections, alveolus 5 and the upper outside alveolus 6 on top block tongue sheet 4 hasp mutually in now going up, alveolus 11 and the lower outside alveolus 12 on below block tongue sheet 10 hasp mutually in lower, the lock 8 that links closely is positioned at the groove 3 that links closely, and the longer axis parallel of the major axis of bar-shaped snap close 24 and the groove 3 that links closely, the body layer 1 of the left and right sides is drawn close mutually, the rubber layer 2 of the left and right sides is drawn close and the semicircular structure 9 of both sides and Mus tail close contact mutually, then the shank of the key 23 linked closely on lock 8 that each fixture is upper and lower is pressed successively, along with chondritic 25 is with shape structure 26 of starting moving to press down, make upper and lower block tongue sheet lower curved in groove 28, until bar-shaped snap close 24 arrives hole 27 plane that links closely, then rotate the lock 8 that links closely and reach 90 °, bar-shaped snap close 24 is made to be positioned at hole 27 of linking closely, thus make whole fixture more firmly be fixed on Mus tail, before bulging outrigger is installed to fixture, in advance stud groove bar 14 and nest shape connecting rod 20 are contacted with each other, between the two without distance, the operation of this process is first alignd with indicatrix 22 by chromonema 21, pore space structure 19 now on spherical stud 16 and the pore space structure 19 on nest shape connecting rod 20 are point-blank, then locking rod 15 is inserted in pore space structure 19, now rotate stud groove bar 14, until make stud groove bar 14 and nest shape connecting rod 20 contact with each other to without distance, and by rotary sleeve tubing string 13, make the length of a side foot-stand equal with the length of tail side foot-stand 17, after this process terminates, the foot rest sleeve of the both sides end to end of bulging outrigger is entered in bulging groove 7, now rotate the interior swivel nut pipe on bulging bar 18, bulging bar 18 is shortened, thus increase in whole intervertebral disc and the pressure of cartilage endplate.
Claims (8)
1. a Mus caudal vertebra pressue device, it is characterized in that: be configured to by outside fixture, bulging, described fixture has two end to end, the same side of two described fixtures has a bulging groove (7) respectively, described bulging groove (7) respectively with the foot rest phase sleeve of the both sides end to end of described bulging outrigger.
2. Mus caudal vertebra pressue device according to claim 1, is characterized in that: described fixture, and two structures are identical end to end for it, and by left and right sides two parts composition, both are connected by the mutual hasp of inside and outside alveolus.
3. Mus caudal vertebra pressue device according to claim 2, it is characterized in that: described fixture left part, be made up of body layer (1) and rubber layer (2), overall in one " C " shape structure, described body layer (1) is made up of hard material, the outer surface central authorities that upper and lower walks crosswise district have a groove that links closely (3) respectively, link closely hole (27) in the described groove that links closely (3) inside, described upper and lower walks crosswise district's center of inside a groove (28) respectively, opening is towards right side, the groove (28) in district is walked crosswise in described top, lower surface in it is distributed with interior alveolus (5), oblique left side, described upper interior alveolus (5) and upper outside alveolus (6) the phase hasp on top block tongue sheet (4) of described fixture right part, the groove (28) in district is walked crosswise in described below, upper surface in it is distributed with lower interior alveolus (11), oblique left side, described lower interior alveolus (11) and lower outside alveolus (12) the phase hasp on below block tongue sheet (10) of described fixture right part, there are a bulging groove (7) in described central authorities of stringer district, body layer (2) left side, be seamless sleeve with the foot rest of described bulging outrigger, described rubber layer (2) is fixed on the inner surface of described body layer (1), on the right side of it, central authorities are a semicircular structure (9).
4. Mus caudal vertebra pressue device according to claim 2, it is characterized in that: described fixture right part, be made up of body layer (1) and rubber layer (2), overall in an inverted " C " shape structure, described body layer (1) is made up of hard material, upper and lower walks crosswise the block tongue sheet that central authorities of district respectively have to stretch to the left, described block tongue sheet is made up of bendable material, the first half area distribution of the lower surface of described top block tongue sheet (4) has upper outside alveolus (6), oblique right side, described upper outside alveolus (6) and described upper interior alveolus (11) phase hasp, the upper surface front center of described top block tongue sheet (4) has a brood of shape structure (26), itself and the top chondritic (25) of locking (8) lower end that links closely is connected in ball-and-socket, the first half area distribution of the upper surface of described below block tongue sheet (10) has lower outside alveolus (12), oblique right side, described lower outside alveolus (12) and described lower interior alveolus (11) phase hasp, the lower surface front center of described below block tongue sheet (10) has a brood of shape structure (26), itself and the below chondritic (25) of locking (8) lower end that links closely is connected in ball-and-socket.
5. Mus caudal vertebra pressue device according to claim 4, it is characterized in that: the described lock (8) that links closely, there is upper and lower two, and structure is identical, by shank of the key (23), lock core forms, both are structure as a whole, described lock core lower end is chondritic (25), it is connected in ball-and-socket with described nest shape structure (26), both are inseparable, and the described lock (8) that links closely can rotate freely being parallel on described block tongue plate plane, described lock core there is a bar-shaped snap close (24), itself and described hole of linking closely (27) snap close mutually, the length of described bar-shaped snap close (24) is greater than the width of the described groove that links closely (3), and be less than the width in described hole of linking closely (27), described shank of the key (23) is a club shaped structure, its central authorities are fixed on described lock core.
6. Mus caudal vertebra pressue device according to claim 1, it is characterized in that: described bulging outrigger, by the foot rest of both sides and the bulging bar (18) of central authorities form end to end, both are structure as a whole, described head side foot-stand, by casing string (13), stud groove bar (14), spherical stud (16), nest shape connecting rod (20), locking rod (15) forms, described casing string (13) and described stud groove bar (14) are threaded, described stud groove bar (14) and described spherical stud (16) are threaded, described spherical stud (16) is connected in ball-and-socket with described nest shape connecting rod (20), described locking rod (15) and described spherical stud (16) and described nest shape connecting rod (20) phase sleeve, described casing string (13), its one end is for entering groove post, with described bulging groove (7) in seamless sleeve, the other end is interior swivel nut pipe, be threaded with the stud end of described stud groove bar (14), described stud groove bar (14), its one end is stud end, be threaded with the interior swivel nut pipe of described casing string (13), there are a groove in other end central authorities, female thread structure is distributed with in it, the stud end of described female thread structure and described spherical stud (16) is threaded, described spherical stud (16), its one end is stud end, be threaded with described female thread structure, the stud end of described spherical stud (16) has a chromonema (21), it is for being partly colored the line of screw thread, and with stud longer axis parallel, the extended line of described chromonema (21) is by the pore space structure (19) on described spherical stud (16), the other end of described spherical stud (16) is porose chondritic, be that ball-and-socket is connected with the porose nest shape structure of described nest shape connecting rod (20), described porose chondritic there is a pore space structure (19), itself and described locking rod (15) phase sleeve, described nest shape connecting rod (20), one end is porose nest shape structure, it is that ball-and-socket is connected with described porose chondritic, it there is a pore space structure (19), with described locking rod (15) phase sleeve, described porose nest shape structure there is an indicatrix (22), its extended line is by the pore space structure (19) of described porose nest shape structure, the other end of described nest shape connecting rod (20) is connected with the head end of described bulging bar (18), both are structure as a whole.
7. Mus caudal vertebra pressue device according to claim 6, it is characterized in that: described bulging bar (18), it is connected with the foot rest end to end described in both sides at two ends end to end, both are structure as a whole, middle body is stud sleeve structure, described stud sleeve structure by interior swivel nut pipe and end to end two studs form, the hand of spiral of two described studs is contrary end to end, pitch and diameter identical, and be threaded with interior swivel nut pipe respectively, described interior swivel nut pipe, the hand of spiral at its inner surface two ends is end to end contrary, pitch and diameter identical, and be threaded with the stud of homonymy respectively.
8. Mus caudal vertebra pressue device according to claim 6, it is characterized in that: described tail side foot-stand (17), its one end and described bulging groove (7) are in seamless sleeve, and the other end is connected with the tail end of described bulging bar (18), and both are structure as a whole.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510560998.5A CN105213062A (en) | 2015-09-07 | 2015-09-07 | A kind of Mus caudal vertebra pressue device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510560998.5A CN105213062A (en) | 2015-09-07 | 2015-09-07 | A kind of Mus caudal vertebra pressue device |
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| CN105213062A true CN105213062A (en) | 2016-01-06 |
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| CN201510560998.5A Pending CN105213062A (en) | 2015-09-07 | 2015-09-07 | A kind of Mus caudal vertebra pressue device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109363790A (en) * | 2018-12-18 | 2019-02-22 | 上海市东方医院 | Tail bone intervertebral disc degeneration experimental provision |
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| US4261295A (en) * | 1977-09-06 | 1981-04-14 | Humie Kanetake | Restraining device for small animals |
| US4709660A (en) * | 1985-04-05 | 1987-12-01 | Regents Of The University Of Minnesota | Instrument and method for accessing vessels and tissues within animals |
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| CN109363790B (en) * | 2018-12-18 | 2023-11-21 | 上海市东方医院 | Experimental device for degeneration of coccyx intervertebral disc |
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Application publication date: 20160106 |