CN105193517A - Toothbrush containing narrow spectral LED (Light-Emitting Diode) red light - Google Patents

Toothbrush containing narrow spectral LED (Light-Emitting Diode) red light Download PDF

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Publication number
CN105193517A
CN105193517A CN201510579818.8A CN201510579818A CN105193517A CN 105193517 A CN105193517 A CN 105193517A CN 201510579818 A CN201510579818 A CN 201510579818A CN 105193517 A CN105193517 A CN 105193517A
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CN
China
Prior art keywords
emitting diode
led
circuit module
light emitting
toothbrush containing
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Pending
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CN201510579818.8A
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Chinese (zh)
Inventor
张�林
王宏
王永兰
李长义
邓嘉胤
高平
徐津
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STOMATOLOGICAL HOSPITAL TIANJIN MEDICAL UNIVERSITY
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STOMATOLOGICAL HOSPITAL TIANJIN MEDICAL UNIVERSITY
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Priority to CN201510579818.8A priority Critical patent/CN105193517A/en
Publication of CN105193517A publication Critical patent/CN105193517A/en
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Abstract

The invention discloses a toothbrush containing narrow spectral LED (Light-Emitting Diode) red light. The toothbrush comprises a handle, wherein a brush rod with a built-in circuit module is connected to the handle; a control switch electrically connected with the circuit module is arranged on the outer surface of the brush rod; a brush head with a built-in LED is connected to the upper end of the brush rod; the LED is electrically connected with the circuit module; a light hole is formed in a position, corresponding to the LED, in the middle of the brush head; circular bristles connected with a control device are arranged along the periphery of the light hole. According to the toothbrush, the activity of white blood cells and the release of growth factors can be increased, the microcirculation of periodontal lesion tissues is improved, the gingival index in periodontitis is remarkably reduced, and the effect of effective anti-inflammatory can be achieved.

Description

A kind of toothbrush containing narrow spectrum LED HONGGUANG
Technical field
The present invention relates to a kind of oral care device, especially relate to a kind of toothbrush containing narrow spectrum LED HONGGUANG.
Background technology
Periodontal disease (periodontaldisease, PD) be that the mankind are modal one of to catch, the sickness rate of 10-60% is had in adult, along with China's aged tendency of population, the recall rate of periodontal disease is in ascendant trend year by year, with the growth at age, prevalence and the order of severity increase all gradually, have had a strong impact on people ' s health.
The reason of periodontal disease is the inflammatory reaction that the interphase interaction of the immunoreation of periodontal pathogen and host produces.Inflammation is the primary reaction of periodontal tissue's infringement, and the common trait of chronic inflammatory disease is monocytic gathering.Mononuclear cell is the important component part of host defense system.A key player is played between host and the balance infecting periodontal tissue antibacterial.Migrating of these cells is a complicated process, and wherein chemotactic factor is key factor.Chemotactic factor produces chemotaxis to leukocyte, activated leukocyte, by the different types of leukocyte of chemotactic, produces various immunoreation and plays a significant role in periodontitis.
CCL2 (MCP 1 also can represent with MCP-1) is mainly through having significant chemotactic and activation with its receptor CCR2 effect to monocyte/macrophage.In chronic periodontitis, the endotheliocyte in gingiva tissue, fibroblast, mononuclear phagocyte produces CCL2.LPS intense stimulus CCL2 high expressed.The CCL2 of high expressed is by the monocyte chemotactic in blood circulation in periodontal tissue, and then mononuclear cell maturation under various stimulation is macrophage.Macrophage quantity increases, and kills pathogen, and release proinflammatory medium and cytokine, as IL-1, TNF-a, bring out the absorption of osseous tissue.The cytokines such as IL-1b, TNF-a can make the expression of CCL2 in gingiva tissue increase further, and result inflammatory cell more assembles the further destruction of causing periodontal tissue.In the gingiva tissue infected, CCL2 express cell quantity is associated with degree of inflammation.In chronic periodontitis and aggressive periodontitis level in gingival sulcus fluid, CCL2 expresses and significantly raises, and is proportionate with clinical depth of probe and attachment loss.Therefore, the development of CCL2 to periodontitis plays a significant role.
Periodontal disease is again the latent dangerous factor affecting many systemic diseases.Patients with periodontitis whole body system inflammation can increase, as in blood, inflammation biology mark can increase.The increase of whole body system inflammation can to cardiovascular disease, and premature labor, diabetes, respiratory system disease has an impact.Cardiovascular disease and periodontitis are related, and the CCL2 expression in blood can as the inflammation biology mark of periodontal disease.During periodontitis, in blood, CCL2 high expressed may increase the generation of the diseases such as atherosclerosis.In lupus erythematosus, diabetes, obstructive pulmonary fibrosis, tumor, rheumatoid arthritis, osteoarthritis, has the high expressed of CCL2 in delayed hypersensitivity blood.Use CCL2 antagonist can the development of chronic arthritis in strong inhibition MRL-lpr Mus, lower arthritic symptom and pathological change.Experiment in vitro display changes CCL2 gene can suppress monocytic chemotactic, suppresses the inflammation of cardiovascular disease to change.CCL2 is the therapeutic goal of the inflammation diseases such as periodontitis.After periodontitis treatment, the clinical indication of periodontitis can be improved, also can reduce CCL2 at blood, level in gingival sulcus fluid, the expression in saliva.Level in gingival sulcus fluid, in saliva, CCL2 expresses to lower and expresses reduction with CCL2 in blood and be associated.Therefore, improve periodontal symptom by Clinical intervention, not only can affect the inflammatory markers in microenvironment, equally, systemic disease is also significantly improved.So reduced the expression of CCL2 by treatment periodontitis, significant to partner treatment above-mentioned whole body system disease.
Periodontal disease (PD) and rheumatoid arthritis (rheumatoidarthritis, RA) have similar immunity and pathological characters, the chronic inflammatory reaction destroyed as caused hard and soft tissue; There are common super inflammation gene expression and functional immunity interference, have similar inflammatory markers and inflammation mechanism, as matrix metalloproteinase and the rising of C reactive protein expression and the loss of local bone, have therebetween and contact closely.The method of many treatment RA also may be used for treating PD, and people wait in expectation equally and study the effective therapy equipment for above-mentioned periodontal disease (PD) that makes new advances, and receive significant therapeutic effect.
Summary of the invention
The object of the invention is to fill up deficiency of the prior art, a kind of application by narrow wave band light source is provided, effectively the toothbrush containing narrow spectrum LED HONGGUANG for the treatment of periodontitis.
The present invention is achieved by following technical proposals: a kind of toothbrush containing narrow spectrum LED HONGGUANG, comprise handle, the brush holder support of circuit module is established in described handle is connected with, the outer surface of described brush holder support is provided with the gauge tap be electrically connected with circuit module, the brush of LED light emitting diode is established in the upper end of described brush holder support is connected with, described LED light emitting diode is electrically connected with circuit module, the position that the middle part of described brush is corresponding with LED light emitting diode is provided with loophole, and the periphery along described loophole is provided with the ring-type bristle be connected with control device.
The battery be connected in parallel with circuit module and control device is provided with in described handle.
Described circuit module comprises, the positive pole of battery is connected in parallel to light emitting diode and motor, the other end of described light emitting diode, connect capacitor, resistor and manostat respectively, described capacitor is connected with manostat with the other end of resistor, and described manostat is connected with the negative pole of battery with motor parallel.
Described control device comprises, motor axostylus axostyle is connected with gear, described gear mesh has tooth sector, described tooth sector is connected with connecting rod by real core rotary shaft, described connecting rod is connected with swing connecting bar, described swing connecting bar is connected with the collar be arranged on hollow rotary shaft bar, the front end of described hollow rotary shaft bar is laterally fixedly connected with the rotary-tray being provided with ring-type bristle, the rear end of described hollow rotary shaft bar is connected with base, and described base is fixedly connected with real core rotating shaft by support bar.
Described LED light emitting diode is the low-yield HONGGUANG that can produce 650 ± 10nm.
Light-passing board is provided with in described loophole.
The invention has the beneficial effects as follows:
One, the present invention arranges LED light emitting diode in toothbrush head, described LED light emitting diode is electrically connected with circuit module, the position that the middle part of described brush is corresponding with LED light emitting diode is provided with loophole, and the periphery along described loophole is provided with the ring-type bristle be connected with control device.Work as starting switch, LED light emitting diode can produce the low-yield HONGGUANG of 650 ± 10nm, irradiates tooth, in known prior art, low-energy laser irradiation (low-levellaserirradiation, LLLI) has the curative effect of antiinflammatory in local and whole body system.Can increase complement, interferon, wait the protection factor of other no special, the pathologic increasing macrophage engulfs activity, strengthens the defencive function of immune protein interferon, and active protection mechanism effect strengthens.And the present invention have employed the principle of low-energy laser irradiation just, by brushing teeth, host cell can be directly acted on and reach reduction gingivitis, promote wound healing; Lower depth of pocket; Increase the early stage hyaline degeneration of tissue of pathological changes.In addition, low-energy laser irradiation can produce the reaction of a series of Photobiology, also good effect is had to the treatment of periodontal disease, low-energy laser can increase the generation of fibroblastic metabolism and collagen, affect the generation of cytokine, increase the release of leukocytic activity and somatomedin, improve the microcirculation of periodontal lesion tissue, gingival index in remarkable reduction periodontitis, the therapeutic effect retention time is also longer.
Two, the control device that toothbrush of the present invention is arranged comprises the gear that motor axostylus axostyle connects, described gear mesh has tooth sector, described tooth sector is connected with connecting rod by real core rotating shaft, described connecting rod is connected with swing connecting bar, described swing connecting bar is connected with the collar be arranged on hollow rotary shaft bar, the front end of described hollow rotary shaft bar is laterally fixedly connected with the rotary-tray being provided with ring-type bristle, the rear end of described hollow rotary shaft bar is connected with base, and described base is fixedly connected with real core rotating shaft by support bar.The bristle of ring-type is formed to swing under the effect of control device, and when brushing teeth, in oral cavity, bristle can carry out back and forth movement up and down along tooth, makes tooth more easy cleaning, and does not destroy gingiva, effectively avoids the drawback that existing people laterally brush teeth.
Three, during the work of its control device of the present invention, independently can work with LED illumination light source, be independent of each other.
Accompanying drawing explanation
Fig. 1 is the Tooth-brush structure schematic diagram that the present invention contains narrow spectrum LED HONGGUANG.
Fig. 2 is the side-looking structural representation of Fig. 1.
Fig. 3 is electrical block diagram of the present invention.
Fig. 4 is brush control device structural representation of the present invention.
Reference numeral: 1 handle 2 brush holder support 3 switch 4LED light emitting diode 5 brush
6 loophole 7 battery 8 ring-type bristle W motor C capacitor R resistors
The real core rotating shaft of LM337 manostat 9 motor axostylus axostyle 10 gear 11 tooth sector 12
13 connecting rod 14 swing connecting bar 15 hollow rotary shaft bar 16 collar 17 rotary-trays
18 base 19 support bars
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is further illustrated:
As Figure 1-4, a kind of toothbrush containing narrow spectrum LED HONGGUANG, LED light emitting diode of the present invention is the low-yield HONGGUANG that can produce 650 ± 10nm, comprise handle 1, the battery 7 be connected in parallel with circuit module and control device is provided with in described handle 1, described handle 1 is connected with brush holder support 2, the outer surface of described brush holder support 2 is provided with the gauge tap 3 be electrically connected with circuit module, the brush 5 of LED light emitting diode 4 is established in the upper end of described brush holder support 2 is connected with, described LED light emitting diode 4 is electrically connected with circuit module, the position that the middle part of described brush 5 is corresponding with LED light emitting diode 4 is provided with loophole 6, light-passing board is provided with in described loophole 6, along the periphery of described loophole 6, be provided with the ring-type bristle 8 be connected with control device.
Circuit module of the present invention comprises, the positive pole of battery 7 is connected in parallel to light emitting diode 4 and motor W, the other end of described light emitting diode 4, connect capacitor C, resistor R and one of them node of manostat LM337 respectively, the other end of described capacitor C is connected with two other node of manostat respectively with the other end of resistor R, and described manostat LM337 is connected with the negative pole of battery 7 with after motor W parallel connection.
Control device of the present invention comprises, motor axostylus axostyle 9 is connected with gear 10, described gear 10 is meshing tooth sector 11, described tooth sector 11 is connected with connecting rod 13 by real core rotating shaft 12, described connecting rod 13 is connected with swing connecting bar 14, described swing connecting bar 14 is connected with the collar 16 be arranged on hollow rotary shaft bar 15, the front end of described hollow rotary shaft bar 15 is laterally fixedly connected with the rotary-tray 17 being provided with ring-type bristle 8, the rear end of described hollow rotary shaft bar 15 is connected with base 18, described base 18 is fixedly connected with real core rotating shaft 12 by support bar 19.
Have experimental data to show, CCL2 and periodontal disease have and contact closely, and there is comparatively significant dependency between periodontitis and RA, RA patient more easily suffers from periodontitis than normal population.Periodontitis treatment has positive role in the sign alleviating RA patient.The treatment of rat experiment display YUNNAN BAIYAO suppresses the development of arthritis, reduces osteoclasosteoclast activating factor (RANKL) in alveolar bone and expresses.Low-energy laser irradiation can promote that people's periodontal ligament cell is bred, and improves the secretion of Cellular alkaline phosphatase activity and fibronectin; Promote osteoblastic proliferation, differentiation, promote the bone formation of animal model, be conducive to the regeneration of periodontal tissue.The improvement effect of auxiliary 2 laser therapies of periodental non-surgical treatment (scalingandrootplanning, SRP) to chronic periodontitis depth of pocket and attachment loss is all obviously better than independent SRP and uses.
Use lightemittingdiode (LED) irradiation in rats rheumatoid arthritis (RA) model can reduce CCL2, the expression of MMP3 gene in rat knee joints synovial tissue.Without under the condition of photosensitizer, lightemittingdiode (LED) irradiation in rats periodontitis experimental model can produce the effect of effective antiinflammatory week pathogen.This is also that can to activate endogenous photosensitizers porphyrin with LED relevant.The clinical patients with periodontitis of LED illumination is pointed out in research, can improve clinical symptoms.Therefore the present invention is used can to reach the effect of effective antiinflammatory with a kind of alternative diode laser light source of LED of noninvasive laser therapy as lightemittingdiode has a narrow wavelength band of non-laser.

Claims (6)

1. the toothbrush containing narrow spectrum LED HONGGUANG, comprise handle, it is characterized in that, the brush holder support of circuit module is established in described handle is connected with, the outer surface of described brush holder support is provided with the gauge tap be electrically connected with circuit module, the brush of LED light emitting diode is established in the upper end of described brush holder support is connected with, described LED light emitting diode is electrically connected with circuit module, the position that the middle part of described brush is corresponding with LED light emitting diode is provided with loophole, and the periphery along described loophole is provided with the ring-type bristle be connected with control device.
2. a kind of toothbrush containing narrow spectrum LED HONGGUANG according to claim 1, is characterized in that, be provided with the battery be connected in parallel with circuit module and control device in described handle.
3. a kind of toothbrush containing narrow spectrum LED HONGGUANG according to claim 1, it is characterized in that, described circuit module comprises, the positive pole of battery is connected in parallel to light emitting diode and motor, the other end of described light emitting diode, connect capacitor, resistor and manostat respectively, described capacitor is connected with manostat with the other end of resistor, and described manostat is connected with the negative pole of battery with motor parallel.
4. a kind of toothbrush containing narrow spectrum LED HONGGUANG according to claim 1, it is characterized in that, described control device comprises, motor axostylus axostyle is connected with gear, described gear mesh has tooth sector, described tooth sector is connected with connecting rod by real core rotary shaft, described connecting rod is connected with swing connecting bar, described swing connecting bar is connected with the collar be arranged on hollow rotary shaft bar, the front end of described hollow rotary shaft bar is laterally fixedly connected with the rotary-tray being provided with ring-type bristle, the rear end of described hollow rotary shaft bar is connected with base, described base is fixedly connected with real core rotating shaft by support bar.
5. a kind of toothbrush containing narrow spectrum LED HONGGUANG according to claim 1, it is characterized in that, described LED light emitting diode is the low-yield HONGGUANG that can produce 650 ± 10nm.
6. a kind of toothbrush containing narrow spectrum LED HONGGUANG according to claim 1, is characterized in that, be provided with light-passing board in described loophole.
CN201510579818.8A 2015-09-11 2015-09-11 Toothbrush containing narrow spectral LED (Light-Emitting Diode) red light Pending CN105193517A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111544780A (en) * 2020-05-15 2020-08-18 中国医学科学院北京协和医院 Temporomandibular joint therapeutic instrument

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1692007A (en) * 2002-09-27 2005-11-02 特里沙控股公司 Method for the production of a toothbrush comprising an electric functional component
CN2907364Y (en) * 2006-05-10 2007-06-06 张鸿斌 Luminous tooth-brush having oral sterilising and health-care function
CN200959931Y (en) * 2006-10-11 2007-10-17 陈崧 Optical wave whitening healthcare toothbrush
CN200987469Y (en) * 2006-11-24 2007-12-12 上海顺驰激光科技有限公司 Laser health care toothbrush
CN101193605A (en) * 2005-03-09 2008-06-04 宝洁公司 Sensor response electric toothbrush and using method
CN102125469A (en) * 2003-09-09 2011-07-20 宝洁公司 Toothbrush with severable electrical connections
CN204951210U (en) * 2015-09-11 2016-01-13 天津医科大学口腔医院 Toothbrush that contains narrow spectrum LED red

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1692007A (en) * 2002-09-27 2005-11-02 特里沙控股公司 Method for the production of a toothbrush comprising an electric functional component
CN102125469A (en) * 2003-09-09 2011-07-20 宝洁公司 Toothbrush with severable electrical connections
CN101193605A (en) * 2005-03-09 2008-06-04 宝洁公司 Sensor response electric toothbrush and using method
CN2907364Y (en) * 2006-05-10 2007-06-06 张鸿斌 Luminous tooth-brush having oral sterilising and health-care function
CN200959931Y (en) * 2006-10-11 2007-10-17 陈崧 Optical wave whitening healthcare toothbrush
CN200987469Y (en) * 2006-11-24 2007-12-12 上海顺驰激光科技有限公司 Laser health care toothbrush
CN204951210U (en) * 2015-09-11 2016-01-13 天津医科大学口腔医院 Toothbrush that contains narrow spectrum LED red

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111544780A (en) * 2020-05-15 2020-08-18 中国医学科学院北京协和医院 Temporomandibular joint therapeutic instrument

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Application publication date: 20151230