CN105168786A - External painkiller for cancers - Google Patents

External painkiller for cancers Download PDF

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Publication number
CN105168786A
CN105168786A CN201510666429.9A CN201510666429A CN105168786A CN 105168786 A CN105168786 A CN 105168786A CN 201510666429 A CN201510666429 A CN 201510666429A CN 105168786 A CN105168786 A CN 105168786A
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China
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parts
radix
pain
externally
radix euphorbiae
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CN201510666429.9A
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Chinese (zh)
Inventor
谢祥波
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Chongiqng Yixintang Trade Co Ltd
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Chongiqng Yixintang Trade Co Ltd
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Priority to CN201510666429.9A priority Critical patent/CN105168786A/en
Publication of CN105168786A publication Critical patent/CN105168786A/en
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Abstract

The invention discloses an external painkiller for cancers. The external painkiller is characterized by consisting of the following components in parts by weight: 30-86 parts of rhizoma chuanxiong, 15-35 parts of ground beetles, 5-78 parts of raw radix aconite, 20-89 parts of gamboges, 15-98 parts of raw radix aconiti agrestis, 13-68 parts of gecko, 21-78 parts of dioscorea bulbifera l, 15-76 parts of centipede, 15-98 parts of semen strychni, 13-98 parts of leech, 23-88 parts of tulipa edulis, 18-78 parts of olibanum, 15-98 parts of raw radix euphorbiae lantu, 13-68 parts of myrrh, 17-89 parts of arisaema saxatile, 18-78 parts of gallnuts, 15-79 parts of Euphorbia pekinensis Rupr., 12-78 parts of realgar, 12-78 parts of sangusis draconis and 8-65 parts of borneol. The external painkiller for cancers is a compound traditional Chinese medicine composition which has an effect of relieving the pain caused by afternoon malignant tumours; 20 types of traditional Chinese medicines are selected, so that the external painkiller has the effects of softening hardness to dissipate stagnation, clearing away toxicity, stopping pain, stimulating the menstrual flow and dissolving stasis, can avoid addiction and dependency, is obvious and long-lasting in pain relieving effect, and does not have a side effect.

Description

Cancer externally-used pain-relieving medicine
Technical field
The present invention relates to a kind of cancer externally-used pain-relieving medicine, belong to field of Chinese herbal.
Background technology
Tumour patient, often along with pain, can bring the torment of pain at middle and advanced stage to patient.The analgesic of current use, as codeine, dolantin, morphine, Pethidine, fentanyl etc., although have analgesic effect, its side effect is comparatively strong, can produce stronger according to patience, not easily long-term taking.So be subject to strict control in administration condition and dosage, let alone the possibility of long-term prescription.Use the ratio for the treatment of by Chinese herbs pain increasing, but be many with Chinese medicine for oral administration or Chinese patent medicine, clinical efficacy is not satisfactory, and relapse rate is high.Find and a kind ofly can keep curative effect for a long time and the pain management method do not rebounded and medicine, become the urgent needs of patient and the highest priority of doctor.
Summary of the invention
For existing problem, the object of the present invention is to provide a kind of cancer externally-used pain-relieving medicine.
To achieve these goals, technical scheme of the present invention is such: a kind of cancer externally-used pain-relieving medicine, is characterized in that: the following component comprising parts by weight:
Rhizoma Chuanxiong 30-86 part, Eupolyphaga Seu Steleophaga 15-35 part, Radix Aconiti 5-78 part, Resina garciniae 20-89 part, Radix Aconiti Kusnezoffii 15-98 part, Gekko Swinhonis 13-68 part, Rhizoma Dioscoreae Bulbiferae 21-78 part, Scolopendra 15-76 part, Semen Strychni 15-98 part, Hirudo 13-98 part, Bulbus Tulipae 23-88 part, Olibanum 18-78 part, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 15-98 part, Myrrha 13-68 part, Rhizoma Arisaematis 17-89 part, Galla Chinensis 18-78 part, Radix Euphorbiae Pekinensis 15-79 part, Realgar 12-78 part, Sanguis Draxonis 12-78 part, Borneolum Syntheticum 8-65 part.
Preferred as such scheme: the following component comprising parts by weight:
Rhizoma Chuanxiong 45-60 part, Eupolyphaga Seu Steleophaga 25-30 part, Radix Aconiti 15-50 part, Resina garciniae 35-60 part, Radix Aconiti Kusnezoffii 35-65 part, Gekko Swinhonis 20-45 part, Rhizoma Dioscoreae Bulbiferae 40-55 part, Scolopendra 30-40 part, Semen Strychni 30-60 part, Hirudo 28-55 part, Bulbus Tulipae 35-50 part, Olibanum 35-50 part, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 28-45 part, Myrrha 25-48 part, Rhizoma Arisaematis 28-42 part, Galla Chinensis 28-40 part, Radix Euphorbiae Pekinensis 29-35 part, Realgar 20-38 part, Sanguis Draxonis 15-32 part, Borneolum Syntheticum 15-29 part.
Preferred as such scheme: the following component comprising parts by weight: Rhizoma Chuanxiong 48 parts, Eupolyphaga Seu Steleophaga 28 parts, Radix Aconiti 30 parts, Resina garciniae 45 parts, Radix Aconiti Kusnezoffii 48 parts, Gekko Swinhonis 29 parts, Rhizoma Dioscoreae Bulbiferae 48 parts, Scolopendra 39 parts, Semen Strychni 42 parts, Hirudo 43 parts, Bulbus Tulipae 38 parts, Olibanum 41 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 33 parts, Myrrha 29 parts, Rhizoma Arisaematis 35 parts, Galla Chinensis 36 parts, 32 parts, Radix Euphorbiae Pekinensis, Realgar 29 parts, Sanguis Draxonis 18 parts, Borneolum Syntheticum 17 parts.
Pharmacology analysis:
The compound traditional Chinese medicine composite composition and effectiveness that this advanced malignant tumor has analgesic effect is as follows:
Rhizoma Chuanxiong: the pungent loose temperature of this product is led to, the pain relieving of energy dispelling wind and removing obstruction in the collateral, again can dispelling the wind and dampness pathogens arthralgia pain.
Eupolyphaga Seu Steleophaga: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Radix Aconiti: expelling wind and removing dampness, antalgic.
Resina garciniae: control swollen ulcer drug, stubborn dermatitis malignant boil, bleeding due to trauma, ulcerative gingivitis decayed tooth, burn.
Radix Aconiti Kusnezoffii: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Gekko Swinhonis: dispel the wind, active, eliminating stagnation.Osteomyelitis, tuberculous lymphadenitis, tumor.Arresting convulsion, removing toxic substances.Control paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil.
Rhizoma Dioscoreae Bulbiferae: removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, cooling blood for hemostasis.For thyromegaly, tuberculous lymphadenitis, laryngopharynx swelling and pain, spits blood, spitting of blood, pertussis, cancerous protuberance; Furuncle is controlled in external.
Scolopendra: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.
Semen Strychni: removing obstruction in the collateral to relieve pain:, dispersing swelling and dissipating binds: with controlling wound pain caused by ecchymoma and ulcer sore pain.In recent years plant cancerous protuberance with Zhiduo County, have certain curative effect.Treatment poliomyelitis sequela, prolapse of lumbar intervertebral disc, trigeminal neuralgia, rheumatoid arthritis, traumatic injury, pain due to blood stasis, anemofrigid-damp arthralgia, general joint contracture, numbness, cancerous protuberance etc.
Hirudo: to have a pain for menstruation apolipsis, lump in the abdomen stomachache, blood-retention, traumatic blood stasis, the disease such as carbuncle erysipelas.
Bulbus Tulipae, is Pseudobulbus cremastrae seu pleiones again, is the bulb of liliaceous plant Tulipa edulis and T.iliensis.Pseudobulbus cremastrae seu pleiones sweet in the mouth, micro-pungent, cold in nature, slightly poisonous, return liver, stomach, spleen channel, the hard matter weight of body, power is high fall loose.There is heat-clearing and toxic substances removing, effect of eliminating carbuncle eliminating stagnation; Cure mainly carbuncle should carbuncle on the back, furuncle to swell the diseases such as malignant boil, scrofula tuberculosis, carcinoma, sore throat, worm venom.For oral administration, external.
Olibanum: have more significant analgesic activity.
Unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae: removing toxic substances, heat clearing away, detumescence..
Myrrha: loose blood blood stasis removing, subduing swelling and relieving pain.
Rhizoma Arisaematis: drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.
Galla Chinensis: astringe the lung; Hidroschesis; Astringing intestine to stop diarrhea; Controlling nocturnal emission with astringent drugs; Hemostasis; Removing toxic substances.Cure mainly: chronic cough of deficiency lung; Spontaneous sweating; Chronic dysentery chronic diarrhea; Proctoptosis; Seminal emission; Nebulousurine; Various hemorrhage; Carbuncle furuncle.
Radix Euphorbiae Pekinensis: the function having removing fluid-retention by purgation, dispersing swelling and dissipating binds.
Realgar: removing toxic substances parasite killing, removing dampness and eliminating phlegm, relieves internal heat anticancer
Sanguis Draxonis: dissipating blood stasis analgesic therapy; Hemostasis; Promoting tissue regeneration and ulcer healing
Borneolum Syntheticum: logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.
In such scheme, by the dosage form of externally-used pain-relieving medicine as patch.Preferred: the dosage form of this externally-used pain-relieving medicine is hydrogel patch.Hydrogel patch good absorbing, not irritated, hydrogel itself also can reducing swelling and alleviating pain, and this patch can ensure medicine uninterruptedly release in 24 hours.
This patch is affixed on the corresponding position of patient (acupuncture point), specifically in table one
In such scheme: the dosage form of this externally-used pain-relieving medicine is unguentum.If be unguentum, can apply according to the acupuncture point in table one.After coating or stick medicine of the present invention, pain alleviates or pain is alleviated.When pain symptom occurs again, change dressings.
The invention has the beneficial effects as follows: the present invention is a kind of compound traditional Chinese medicine composite advanced malignant tumor to analgesic effect, selected two Ten Herbs to there is hard masses softening and resolving, removing toxic substances, promoting blood circulation and stopping pain, stimulating the menstrual flow reaches the effect of network, blood stasis dispelling eliminating mass.Without additive, no dependence, analgesic effect obviously lasting, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described:
Embodiment 1
Be made up of the following medicine of parts by weight:
Rhizoma Chuanxiong 30 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Aconiti 5 parts, Resina garciniae 20 parts, Radix Aconiti Kusnezoffii 15 parts, Gekko Swinhonis 13 parts, Rhizoma Dioscoreae Bulbiferae 21 parts, Scolopendra 15 parts, Semen Strychni 15 parts, Hirudo 13 parts, Bulbus Tulipae 23 parts, Olibanum 18 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 15 parts, Myrrha 13 parts, Rhizoma Arisaematis 17 parts, Galla Chinensis 18 parts, 15 parts, Radix Euphorbiae Pekinensis, Realgar 12 parts, Sanguis Draxonis 12 parts, Borneolum Syntheticum 8 parts.Said medicine is broken into ultramicro powder.External use plaster is made with hydrogel techniques.
Embodiment 2
Be made up of the following medicine of parts by weight:
Rhizoma Chuanxiong 86 parts, Eupolyphaga Seu Steleophaga 35 parts, Radix Aconiti 78 parts, Resina garciniae 89 parts, Radix Aconiti Kusnezoffii 98 parts, Gekko Swinhonis 68 parts, Rhizoma Dioscoreae Bulbiferae 78 parts, Scolopendra 76 parts, Semen Strychni 98 parts, Hirudo 98 parts, Bulbus Tulipae 88 parts, Olibanum 78 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 98 parts, Myrrha 68 parts, Rhizoma Arisaematis 89 parts, Galla Chinensis 78 parts, 79 parts, Radix Euphorbiae Pekinensis, Realgar 78 parts, Sanguis Draxonis 78 parts, Borneolum Syntheticum 65 parts.Said medicine is broken into ultramicro powder.External use plaster is made with hydrogel techniques.
Embodiment 3
Be made up of the following medicine of parts by weight:
Rhizoma Chuanxiong 45 parts, Eupolyphaga Seu Steleophaga 25 parts, Radix Aconiti 15 parts, Resina garciniae 35 parts, Radix Aconiti Kusnezoffii 35 parts, Gekko Swinhonis 20 parts, Rhizoma Dioscoreae Bulbiferae 40 parts, Scolopendra 30 parts, Semen Strychni 30 parts, Hirudo 28 parts, Bulbus Tulipae 35 parts, Olibanum 35 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 28 parts, Myrrha 25 parts, Rhizoma Arisaematis 28 parts, Galla Chinensis 28 parts, 29 parts, Radix Euphorbiae Pekinensis, Realgar 20 parts, Sanguis Draxonis 15 parts, Borneolum Syntheticum 15 parts.Said medicine is broken into ultramicro powder.External use plaster is made with vaseline and Mel.
Embodiment 4
Be made up of the following medicine of parts by weight:
Rhizoma Chuanxiong 60 parts, Eupolyphaga Seu Steleophaga 30 parts, Radix Aconiti 50 parts, Resina garciniae 60 parts, Radix Aconiti Kusnezoffii 65 parts, Gekko Swinhonis 45 parts, Rhizoma Dioscoreae Bulbiferae 55 parts, Scolopendra 40 parts, Semen Strychni 60 parts, Hirudo 55 parts, Bulbus Tulipae 50 parts, Olibanum 50 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 45 parts, Myrrha 48 parts, Rhizoma Arisaematis 42 parts, Galla Chinensis 40 parts, 35 parts, Radix Euphorbiae Pekinensis, Realgar 38 parts, Sanguis Draxonis 32 parts, Borneolum Syntheticum 29 parts.Said medicine is broken into ultramicro powder.External use plaster is made with hydrogel techniques.
Embodiment 5
Be made up of the following component of parts by weight:
Rhizoma Chuanxiong 48 parts, Eupolyphaga Seu Steleophaga 28 parts, Radix Aconiti 30 parts, Resina garciniae 45 parts, Radix Aconiti Kusnezoffii 48 parts, Gekko Swinhonis 29 parts, Rhizoma Dioscoreae Bulbiferae 48 parts, Scolopendra 39 parts, Semen Strychni 42 parts, Hirudo 43 parts, Bulbus Tulipae 38 parts, Olibanum 41 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 33 parts, Myrrha 29 parts, Rhizoma Arisaematis 35 parts, Galla Chinensis 36 parts, 32 parts, Radix Euphorbiae Pekinensis, Realgar 29 parts, Sanguis Draxonis 18 parts, Borneolum Syntheticum 17 parts.Said medicine is broken into ultramicro powder.External use plaster is made with hydrogel techniques.
Clinical trial:
Analysis of cases, clinical tumor makes a definite diagnosis patient 128 example, wherein patients with lung cancer 45 example, patient with breast cancer 23 example, gynecologic tumor 18 example, patients with bowel cancer 15 example, liver cancer patient 12 example, gastric cancer 10 example, urinary tumor patient 5 example.
According to patch of the present invention on the acupoint plaster that table is a kind of, after sticking, pain symptom disappearance 48 example, pain significantly alleviates 62 examples, and pain symptom alleviates 11 examples, and pain symptom minor responses 3 is routine, and not effective 4 examples, total effective rate is up to 96.8%.
The present invention is not limited to above-mentioned specific embodiment, should be appreciated that those of ordinary skill in the art just design according to the present invention can make many modifications and variations without the need to creative work.As the present invention is made other exterior-applied formulations such as unguentum; in a word; all technical staff in the art, all should by the determined protection domain of claims under this invention's idea on the basis of existing technology by the available technical scheme of logical analysis, reasoning, or a limited experiment.

Claims (6)

1. a cancer externally-used pain-relieving medicine, is characterized in that: the following component comprising parts by weight:
Rhizoma Chuanxiong 30-86 part, Eupolyphaga Seu Steleophaga 15-35 part, Radix Aconiti 5-78 part, Resina garciniae 20-89 part, Radix Aconiti Kusnezoffii 15-98 part, Gekko Swinhonis 13-68 part, Rhizoma Dioscoreae Bulbiferae 21-78 part, Scolopendra 15-76 part, Semen Strychni 15-98 part, Hirudo 13-98 part, Bulbus Tulipae 23-88 part, Olibanum 18-78 part, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 15-98 part, Myrrha 13-68 part, Rhizoma Arisaematis 17-89 part, Galla Chinensis 18-78 part, Radix Euphorbiae Pekinensis 15-79 part, Realgar 12-78 part, Sanguis Draxonis 12-78 part, Borneolum Syntheticum 8-65 part.
2. cancer externally-used pain-relieving medicine according to claim 1, is characterized in that: the following component comprising parts by weight:
Rhizoma Chuanxiong 45-60 part, Eupolyphaga Seu Steleophaga 25-30 part, Radix Aconiti 15-50 part, Resina garciniae 35-60 part, Radix Aconiti Kusnezoffii 35-65 part, Gekko Swinhonis 20-45 part, Rhizoma Dioscoreae Bulbiferae 40-55 part, Scolopendra 30-40 part, Semen Strychni 30-60 part, Hirudo 28-55 part, Bulbus Tulipae 35-50 part, Olibanum 35-50 part, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 28-45 part, Myrrha 25-48 part, Rhizoma Arisaematis 28-42 part, Galla Chinensis 28-40 part, Radix Euphorbiae Pekinensis 29-35 part, Realgar 20-38 part, Sanguis Draxonis 15-32 part, Borneolum Syntheticum 15-29 part.
3. cancer externally-used pain-relieving medicine according to claim 1, is characterized in that: the following component comprising parts by weight: Rhizoma Chuanxiong 48 parts, Eupolyphaga Seu Steleophaga 28 parts, Radix Aconiti 30 parts, Resina garciniae 45 parts, Radix Aconiti Kusnezoffii 48 parts, Gekko Swinhonis 29 parts, Rhizoma Dioscoreae Bulbiferae 48 parts, Scolopendra 39 parts, Semen Strychni 42 parts, Hirudo 43 parts, Bulbus Tulipae 38 parts, Olibanum 41 parts, unprocessed radix euphorbiae fischerianae, radix euphorbiae ebracteolatae or radix stellerae 33 parts, Myrrha 29 parts, Rhizoma Arisaematis 35 parts, Galla Chinensis 36 parts, 32 parts, Radix Euphorbiae Pekinensis, Realgar 29 parts, Sanguis Draxonis 18 parts, Borneolum Syntheticum 17 parts.
4. cancer externally-used pain-relieving medicine according to any one of claim 1-3, is characterized in that: the dosage form of this externally-used pain-relieving medicine is patch.
5. cancer externally-used pain-relieving medicine according to claim 4, is characterized in that: the dosage form of this externally-used pain-relieving medicine is hydrogel patch.
6. cancer externally-used pain-relieving medicine according to any one of claim 1-3, is characterized in that: the dosage form of this externally-used pain-relieving medicine is unguentum.
CN201510666429.9A 2015-10-13 2015-10-13 External painkiller for cancers Pending CN105168786A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110058041A (en) * 2009-11-25 2011-06-01 주식회사한국신약 Health functional foods compositions for the prevention and amelioration of cancer containing the mixed extract of phellinus linteus mycelium and cultured panax ginseng cameyer as an active ingredient
CN102688317A (en) * 2012-06-25 2012-09-26 鲁邦卫 Traditional Chinese medicine for treating liver cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110058041A (en) * 2009-11-25 2011-06-01 주식회사한국신약 Health functional foods compositions for the prevention and amelioration of cancer containing the mixed extract of phellinus linteus mycelium and cultured panax ginseng cameyer as an active ingredient
CN102688317A (en) * 2012-06-25 2012-09-26 鲁邦卫 Traditional Chinese medicine for treating liver cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李佩文等: "《癌症疼痛中西医汇通》", 31 January 2002, 辽宁科学技术出版社 *
梁勇才等: "《中国外治妙方》", 31 January 2003, 科学技术文献出版社 *

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