CN105168343A - Compound wax special for resisting scars and preparation method thereof - Google Patents
Compound wax special for resisting scars and preparation method thereof Download PDFInfo
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- CN105168343A CN105168343A CN201510709676.2A CN201510709676A CN105168343A CN 105168343 A CN105168343 A CN 105168343A CN 201510709676 A CN201510709676 A CN 201510709676A CN 105168343 A CN105168343 A CN 105168343A
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Abstract
The invention belongs to the technical field of unguent for resisting scars, and particularly relates to compound wax special for resisting the scars and a preparation method thereof. The compound wax special for resisting the scars is prepared from gallnuts, sesame oil, large blister beetle, trogopterus dung, periostracum serpentis, periostracum serpentis, scorpions, lavender, angelica sinensis and musk. The special wax can effectively remove the scars, and proliferation of newly born skins is facilitated.
Description
Technical field
The invention belongs to the technical field of anti-scar ointment, be specifically related to a kind of Compound Resisting scar Wax special and preparation method thereof.
Background technology
Cicatrix is the inevitable outcome of tissue repair after wound.Scar hyperplasia with after wound healing first 3 ~ 6 months the most obvious, show as that cicatrix color is red, matter hard, sufferings symptom is obvious, outstanding skin surface growth, generally continues to flatten soft gradually in 1 ~ 2 year.Scar tissue is a kind of poor circulation on pathological tissue, textural anomaly, and the tissue of nerve, vascularity entanglement, most tissues cell is in a kind of anaerobic condition, and main manifestations is excessive synthesis and the deposition of collagen.Therefore regulate and control the synthesis of collagen and how to guide collagen ordered arrangement to be the emphasis preventing and treating cicatrix.Affect cicatrization, development and Ripening and Softening factor a lot, cicatrization mechanism is not yet illustrated.Cicatrix is the necessary process that tissue injury repairs, but excessively scar hyperplasia not only causes suffering to patient, returns curative activity and brings very large burden.
Due to primary disease genesis mechanism more complicated, there is no normalized Therapeutic Method at present.Though thus instruct clinical treatment means to have certain curative effect, all there is its limitation.The method of traditional treatment cicatrix is that excision coordinates long-acting hormone local injection, X-ray therapy etc., can be suppressed to fibrocyte proliferation and collage synthesis, but have certain detrimental effect to body, and also the difficult cicatrix that controls recurs.Clinical conventional pressure therapy has certain curative effect to the hyper-proliferative preventing and treating cicatrix, also the shortcoming such as pressure needed for treatment, joint motion are limited, the inconvenient pressurization of neck surface and being restricted because being difficult to reach.
Summary of the invention
The object of the invention is to the defect for above-mentioned existence and provide a kind of Compound Resisting scar Wax special and preparation method thereof, this Wax special effectively can remove cicatrix, promotes the hypertrophy of newborn skin.
Technical scheme of the present invention is: a kind of Compound Resisting scar Wax special, comprises following raw material: Galla Chinensis, Oleum sesami, Mylabris, Oletum Trogopterori, Periostracum Serpentis, Scolopendra, Scorpio, lavandula angustifolia, Radix Angelicae Sinensis, Moschus.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 10-25 part, Scolopendra 35-42 part, Mylabris 20-35 part, Oletum Trogopterori 30-39 part, Periostracum Serpentis 12-27 part, Oleum sesami 21-29 part, Scorpio 35-42 part, lavandula angustifolia 10-25 part, Radix Angelicae Sinensis 20-35 part, Moschus 0.04-0.11 part.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 15-22 part, Scolopendra 38-41 part, Mylabris 22-31 part, Oletum Trogopterori 32-37 part, Periostracum Serpentis 15-24 part, Oleum sesami 22-28 part, Scorpio 37-40 part, lavandula angustifolia 13-21 part, Radix Angelicae Sinensis 21-32 part, Moschus 0.05-0.10 part.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 20 parts, Scolopendra 39 parts, Mylabris 28 parts, Oletum Trogopterori 35 parts, Periostracum Serpentis 22 parts, Oleum sesami 25 parts, Scorpio 38 parts, lavandula angustifolia 19 parts, Radix Angelicae Sinensis 29 parts, 0.09 part, Moschus.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 10 parts, Scolopendra 35 parts, Mylabris 20 parts, Oletum Trogopterori 30 parts, Periostracum Serpentis 12 parts, Oleum sesami 21 parts, Scorpio 35 parts, lavandula angustifolia 10 parts, Radix Angelicae Sinensis 20 parts, 0.04 part, Moschus.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 25 parts, Scolopendra 42 parts, Mylabris 35 parts, Oletum Trogopterori 39 parts, Periostracum Serpentis 27 parts, Oleum sesami 29 parts, Scorpio 42 parts, lavandula angustifolia 25 parts, Radix Angelicae Sinensis 35 parts, 0.11 part, Moschus.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 15 parts, Scolopendra 38 parts, Mylabris 22 parts, Oletum Trogopterori 32 parts, Periostracum Serpentis 15 parts, Oleum sesami 22 parts, Scorpio 37 parts, lavandula angustifolia 13 parts, Radix Angelicae Sinensis 21 parts, 0.05 part, Moschus.
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 22 parts, Scolopendra 41 parts, Mylabris 31 parts, Oletum Trogopterori 37 parts, Periostracum Serpentis 24 parts, Oleum sesami 28 parts, Scorpio 40 parts, lavandula angustifolia 21 parts, Radix Angelicae Sinensis 32 parts, 0.10 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Beneficial effect of the present invention is: Compound Resisting scar Wax special of the present invention, comprises following raw material: Galla Chinensis, Oleum sesami, Mylabris, Oletum Trogopterori, Periostracum Serpentis, Scolopendra, Scorpio, lavandula angustifolia, Radix Angelicae Sinensis, Moschus.Described Compound Resisting scar Wax special is suppressed to fibroblast proliferation by protein precipitation, impels thin vessels to shrink, and reduces cicatrix blood supply, reaches and suppresses cicatrix growth object.Have obvious inhibitory action to the fibroblasts from hypertrophic scars of In vitro culture, energy blood vessel dilating, improves microcirculation, carries out clinical experiment as follows below stronger to the suppression of collagen protein synthesis to described Compound Resisting scar Wax special.
1 data and method
1.1 physical data: select hypertrophic cicatrix patient 160 example, wherein man 52 example, female 108 example; 14 ~ 58 years old age, average out to 32.8 years old.Traumatogenic reason: burn 65 example, traffic accident wound 46 example, 26 examples of scratching, 23 examples chopped wound by cutter; Cicatrix position: face 116 example, shirtfront 30 example, the back of the hand 14 example; Post burn: be less than 1 month 28 example, 1 ~ 3 month 94 example, 3 ~ 6 months 38 example.Random point two groups, often organize 80 examples, grouping is not by consultation time successively restriction, and the conditions such as age, sex, cicatrix classification, generation time length, the course for the treatment of of often organizing all have comparability.
1.2 Therapeutic Method: treatment group: first clean affected part with warm water, then get Compound Resisting scar Wax special and are applied to cicatrix place in right amount.Matched group: adopt traditional anti-cicatrix ointment.
1.3 curative effect determinate standards: substantially cure: cicatrix sufferings disappear, from hard to soft, color transfers pale red to by cerise or close to normal skin tone to quality, hardness and color perfecting > 90%; Effective: cicatrix sufferings alleviate, from hard to soft, color transfers pale red to by cerise to quality, hardness and color perfecting > 60%; Take a turn for the better: cicatrix sufferings have and to a certain degree alleviate, hardness and color perfecting > 30%; Invalid: the unchanged even hypertrophy of cicatrix increases the weight of.
1.4 effect assessments: observe time that cicatrix softens or disappear, degree, whether recur, safety and patient satisfaction.The capable Mann-WhitneyU non parametric tests of related data, with P < 0.05 for there being significant difference.
2 results
The 160 routine patients selected all observe and follow up a case by regular visits to 3 ~ 6 months, to external used medicine all without obvious side reaction.Two groups of comparitive study are in table 1, and the capable Mann-WhitneyU non parametric tests of related data, during treatment group two weeks, major part is softening for treatment group cicatrix.During 1 month treatment time, treatment group cures 43 examples substantially, effective 35 examples, and take a turn for the better 1 example, invalid 1 example; Matched group cures 0 example substantially, effective 5 examples, and take a turn for the better 39 examples, invalid 36 examples.During 2 months treatment times, treatment group cures 78 examples substantially, effective 2 examples; Matched group cures 5 examples substantially, effective 25 examples, and take a turn for the better 42 examples, invalid 8 examples.
Detailed description of the invention
Below by embodiment, the present invention is described in detail.
Embodiment 1
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 20 parts, Scolopendra 39 parts, Mylabris 28 parts, Oletum Trogopterori 35 parts, Periostracum Serpentis 22 parts, Oleum sesami 25 parts, Scorpio 38 parts, lavandula angustifolia 19 parts, Radix Angelicae Sinensis 29 parts, 0.09 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Embodiment 2
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 10 parts, Scolopendra 35 parts, Mylabris 20 parts, Oletum Trogopterori 30 parts, Periostracum Serpentis 12 parts, Oleum sesami 21 parts, Scorpio 35 parts, lavandula angustifolia 10 parts, Radix Angelicae Sinensis 20 parts, 0.04 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Embodiment 3
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 25 parts, Scolopendra 42 parts, Mylabris 35 parts, Oletum Trogopterori 39 parts, Periostracum Serpentis 27 parts, Oleum sesami 29 parts, Scorpio 42 parts, lavandula angustifolia 25 parts, Radix Angelicae Sinensis 35 parts, 0.11 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Embodiment 4
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 15 parts, Scolopendra 38 parts, Mylabris 22 parts, Oletum Trogopterori 32 parts, Periostracum Serpentis 15 parts, Oleum sesami 22 parts, Scorpio 37 parts, lavandula angustifolia 13 parts, Radix Angelicae Sinensis 21 parts, 0.05 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, it is characterized in that, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Embodiment 5
Described Compound Resisting scar Wax special, comprises the raw material of following weight portion: Galla Chinensis 22 parts, Scolopendra 41 parts, Mylabris 31 parts, Oletum Trogopterori 37 parts, Periostracum Serpentis 24 parts, Oleum sesami 28 parts, Scorpio 40 parts, lavandula angustifolia 21 parts, Radix Angelicae Sinensis 32 parts, 0.10 part, Moschus.
The preparation method of described Compound Resisting scar Wax special, comprises pulverizing, soak extraction and preparation, it is characterized in that, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Claims (9)
1. a Compound Resisting scar Wax special, is characterized in that, comprises following raw material: Galla Chinensis, Oleum sesami, Mylabris, Oletum Trogopterori, Periostracum Serpentis, Scolopendra, Scorpio, lavandula angustifolia, Radix Angelicae Sinensis, Moschus.
2. want Compound Resisting scar Wax special described in 1 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 10-25 part, Scolopendra 35-42 part, Mylabris 20-35 part, Oletum Trogopterori 30-39 part, Periostracum Serpentis 12-27 part, Oleum sesami 21-29 part, Scorpio 35-42 part, lavandula angustifolia 10-25 part, Radix Angelicae Sinensis 20-35 part, Moschus 0.04-0.11 part.
3. want Compound Resisting scar Wax special described in 2 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 15-22 part, Scolopendra 38-41 part, Mylabris 22-31 part, Oletum Trogopterori 32-37 part, Periostracum Serpentis 15-24 part, Oleum sesami 22-28 part, Scorpio 37-40 part, lavandula angustifolia 13-21 part, Radix Angelicae Sinensis 21-32 part, Moschus 0.05-0.10 part.
4. want Compound Resisting scar Wax special described in 3 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 20 parts, Scolopendra 39 parts, Mylabris 28 parts, Oletum Trogopterori 35 parts, Periostracum Serpentis 22 parts, Oleum sesami 25 parts, Scorpio 38 parts, lavandula angustifolia 19 parts, Radix Angelicae Sinensis 29 parts, 0.09 part, Moschus.
5. want Compound Resisting scar Wax special described in 2 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 10 parts, Scolopendra 35 parts, Mylabris 20 parts, Oletum Trogopterori 30 parts, Periostracum Serpentis 12 parts, Oleum sesami 21 parts, Scorpio 35 parts, lavandula angustifolia 10 parts, Radix Angelicae Sinensis 20 parts, 0.04 part, Moschus.
6. want Compound Resisting scar Wax special described in 2 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 25 parts, Scolopendra 42 parts, Mylabris 35 parts, Oletum Trogopterori 39 parts, Periostracum Serpentis 27 parts, Oleum sesami 29 parts, Scorpio 42 parts, lavandula angustifolia 25 parts, Radix Angelicae Sinensis 35 parts, 0.11 part, Moschus.
7. want Compound Resisting scar Wax special described in 3 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 15 parts, Scolopendra 38 parts, Mylabris 22 parts, Oletum Trogopterori 32 parts, Periostracum Serpentis 15 parts, Oleum sesami 22 parts, Scorpio 37 parts, lavandula angustifolia 13 parts, Radix Angelicae Sinensis 21 parts, 0.05 part, Moschus.
8. want Compound Resisting scar Wax special described in 3 according to right, it is characterized in that, comprise the raw material of following weight portion: Galla Chinensis 22 parts, Scolopendra 41 parts, Mylabris 31 parts, Oletum Trogopterori 37 parts, Periostracum Serpentis 24 parts, Oleum sesami 28 parts, Scorpio 40 parts, lavandula angustifolia 21 parts, Radix Angelicae Sinensis 32 parts, 0.10 part, Moschus.
9. right wants a preparation method for Compound Resisting scar Wax special described in 1, comprises pulverizing, soak extraction and preparation, it is characterized in that, soaks 6 months; Preparation adopts Cera Flava or paraffin as excipient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510709676.2A CN105168343A (en) | 2015-10-28 | 2015-10-28 | Compound wax special for resisting scars and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510709676.2A CN105168343A (en) | 2015-10-28 | 2015-10-28 | Compound wax special for resisting scars and preparation method thereof |
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| CN105168343A true CN105168343A (en) | 2015-12-23 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105944030A (en) * | 2016-06-27 | 2016-09-21 | 王青年 | Traditional Chinese medicine restoring liquid for healing scars and acne marks |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1456330A (en) * | 2003-03-28 | 2003-11-19 | 施梦月 | Scar eliminating medicine |
| CN102068489A (en) * | 2009-11-19 | 2011-05-25 | 谢菊荣 | Externally applied medicine for treating wound ulcer |
| CN102416127A (en) * | 2011-12-09 | 2012-04-18 | 崔国志 | Chinese medicinal powder for treating psoriasis |
-
2015
- 2015-10-28 CN CN201510709676.2A patent/CN105168343A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1456330A (en) * | 2003-03-28 | 2003-11-19 | 施梦月 | Scar eliminating medicine |
| CN102068489A (en) * | 2009-11-19 | 2011-05-25 | 谢菊荣 | Externally applied medicine for treating wound ulcer |
| CN102416127A (en) * | 2011-12-09 | 2012-04-18 | 崔国志 | Chinese medicinal powder for treating psoriasis |
Non-Patent Citations (1)
| Title |
|---|
| 黄泽春等: "按摩配合抗疤药膜治疗早期增生性瘢痕的疗效观察", 《中国美容医学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105944030A (en) * | 2016-06-27 | 2016-09-21 | 王青年 | Traditional Chinese medicine restoring liquid for healing scars and acne marks |
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Application publication date: 20151223 |