CN105125847A - Sleep improvement medicine and preparation method thereof - Google Patents
Sleep improvement medicine and preparation method thereof Download PDFInfo
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- CN105125847A CN105125847A CN201510565715.6A CN201510565715A CN105125847A CN 105125847 A CN105125847 A CN 105125847A CN 201510565715 A CN201510565715 A CN 201510565715A CN 105125847 A CN105125847 A CN 105125847A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and discloses a sleep improvement medicine and a preparation method thereof. The sleep improvement medicine is composed of, by weight, 10-20 parts of rhodiola rosea, 10-20 parts of fructus schisandrae chinensis, 5-15 parts of radix polygoni multiflori, 5-15 parts of fructus hippophae, 10-20 parts of semen nelumbinis, 3-9 parts of radix ophiopogonis, 4-16 parts of ganoderma lucidum, 3-9 parts of radix glycyrrhizae, 5-15 parts of tuber fleeceflower stem, 1-5 parts of radix scrophulariae and 1-5 parts of salvia miltiorrhiza. The sleep improvement medicine has an excellent sleep improvement function with no adverse effect, and safety in use, simplicity of the preparation method, high production degree, stability and reliability in quality of products and suitableness for large-scale production are realized.
Description
Technical field
The present invention relates to medicine of a kind of improving water flood and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Sleep is the necessary process of life, and being that body restores, integrates and the important step of consolidating memory, is healthy indispensable important component part.Along with the continuous propelling of modernization, social competition is day by day fierce, and the work of people and rhythm of life are accelerated, and remains difficult and constantly rises for the sickness rate of the insomnia of feature, more and more become a kind of commonly encountered diseases, the frequently-occurring disease of modern society to fall asleep and sleep.Chronic insomnia can bring huge infringement to the physical and mental health of people.Do not have enough sleep and body immunity not only can be made to decline, the ability of rehabilitation disease also can be made to reduce, bring out the outbreak of original disease.
According to World Health Organization's investigation, the whole world has the people of 27% to have sleeping problems, has the sleep disorder of 45% various degrees in Chinese.The whole world sleep that international mental health tissue is sponsored and health plan have been initiated one in calendar year 2001 global activity---by annual March 21, namely the first day in spring have been decided to be " World Sleep Day ", visible, sleep and receive worldwide concern already.
At present, all kinds of improving water flood products that market is popular, mostly go to seek formula in poor aspect from calmness, hypnosis and adjustment round the clock.Be that the health promoting product of primary raw material is only adapted to graveyard shift workers with melatonin, needs get jet lag, person in middle and old age's (because melatonin secretion reduces), if crowd's medicine daytime is residual comparatively large, has dizzy and walk and unstablely wait side effect, may give older, health comparatively weak person bring danger.But, cause sleep disorder to have from many-sided factor, such as ailing, brain continuous print is overexcited or fatigue, stress, emotion setback, fear, neurasthenia, spiritual irriate etc.And in most cases, poor rule is upset just sleep disorder round the clock, in nascent a kind of form of expression, is not the cause of disease.The sleep disorder that causes of poor rule confusion, after all not at majority, and recovers poor rule round the clock and can not solve the basic reason of sleep disorder round the clock still more.Therefore, the long-term favor of consumer can not be obtained.Therefore, in conjunction with Chinese medical theory, develop fundamentally solve sleep disorder, improving water flood Chinese medicine imperative.
Summary of the invention
The object of the invention is to make up the deficiencies in the prior art, medicine of a kind of improving water flood and preparation method thereof is provided.The medicine of improving water flood of the present invention, its raw material all has the function of definite relieving insomnia symptom, improving water flood quality, adjustment sleep rhythm, has the effect of good improving water flood.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of medicine of improving water flood, comprises the raw material of following parts by weight: Radix Rhodiolae 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Radix Polygoni Multiflori 5 ~ 15 parts, Fructus Hippophae 5 ~ 15 parts, 10 ~ 20 parts, Semen Nelumbinis, Radix Ophiopogonis 3 ~ 9 parts, Ganoderma 4 ~ 16 parts, 3 ~ 9 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 5 ~ 15 parts, Radix Scrophulariae 1 ~ 5 part and Radix Salviae Miltiorrhizae 1 ~ 5 part.
The function of several raw material of the present invention is respectively: Radix Rhodiolae, sweet in the mouth, hardship, and property is put down, and returns lung, heart channel, has benefiting QI for activating blood circulation, effect of relievining asthma of promoting blood circulation; Fructus Schisandrae Chinensis, sour in the mouth, sweet, warm in nature, return lung, the heart, kidney channel, astringe the lung, nourishing kidney, promote the production of body fluid, receive antiperspirant, arresting seminal emission to effect; Radix Polygoni Multiflori, bitter in the mouth, sweet, puckery, slightly warm in nature, returns liver, kidney channel, has nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels the wind, detoxifies to effect; Fructus Hippophae, sweet in the mouth, acid, warm in nature, return spleen, stomach, lung, heart channel, have effect of strengthening the spleen to promote digestion, eliminating phlegm and stopping cough, blood circulation promoting and blood stasis dispelling; Semen Nelumbinis, sweet in the mouth, puckery, property is put down, and has spleen reinforcing antidiarrheal, leukorrhagia stopping, kidney tonifying arresting seminal emission, effect of tranquilizing by nourishing the heart; Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, GUIXIN, lung, stomach warp, have YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire; Ganoderma, sweet in the mouth, property is put down, and returns lung, the heart, spleen, kidney channel, has the effect strengthening body immunity, regulate blood glucose, control blood pressure; Radix Glycyrrhizae, sweet in the mouth, property is put down, and returns spleen, stomach, lung meridian, has effect of QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription; Caulis Polygoni Multiflori, sweet in the mouth, micro-hardship, property is put down, GUIXIN, spleen, kidney, Liver Channel, has nourishing heart, calms the nerves, dredging collateral, the effect of dispeling the wind; Radix Scrophulariae, sweet in the mouth, hardship, salty, cold nature, returns lung, stomach, kidney channel, has effect of clearing away heat and cooling blood, removing toxic substances, eliminating stagnation sore-throat relieving, YIN nourishing; Radix Salviae Miltiorrhizae, bitter in the mouth, cold nature, GUIXIN, Liver Channel, have effect of the detumescence of promoting blood circulation to remove obstruction in the collateral, removing heat from blood, the relieving restlessness that clears away heart-fire.
On the basis of technique scheme, the present invention can also do following improvement.
Further, the raw material of following parts by weight is comprised: Radix Rhodiolae 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Polygoni Multiflori 10 parts, Fructus Hippophae 10 parts, 15 parts, Semen Nelumbinis, Radix Ophiopogonis 6 parts, Ganoderma 10 parts, 6 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 10 parts, Radix Scrophulariae 3 parts and Radix Salviae Miltiorrhizae 3 parts.
A preparation method for the medicine of improving water flood, comprises the steps:
(1) raw material of following parts by weight is taken: Radix Rhodiolae 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Radix Polygoni Multiflori 5 ~ 15 parts, Fructus Hippophae 5 ~ 15 parts, 10 ~ 20 parts, Semen Nelumbinis, Radix Ophiopogonis 3 ~ 9 parts, Ganoderma 4 ~ 16 parts, 3 ~ 9 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 5 ~ 15 parts, Radix Scrophulariae 1 ~ 5 part and Radix Salviae Miltiorrhizae 1 ~ 5 part;
(2) raw material mixing step (1) taken, add the water of 6 ~ 8 times amount, after ultrasonic extraction, filter, filtrate is concentrated into the thick paste that relative density is 1.1 ~ 1.2, spraying dry is 3 ~ 5% to moisture content, obtains the active component of the medicine of described improving water flood, add pharmaceutically acceptable adjuvant, obtain the medicine of described improving water flood.
On the basis of technique scheme, the present invention can also do following improvement.
Further, the parts by weight of step (1) described raw material are: Radix Rhodiolae 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Polygoni Multiflori 10 parts, Fructus Hippophae 10 parts, 15 parts, Semen Nelumbinis, Radix Ophiopogonis 6 parts, Ganoderma 10 parts, 6 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 10 parts, Radix Scrophulariae 3 parts and Radix Salviae Miltiorrhizae 3 parts.
Further, the temperature of step (2) described ultrasonic extraction is 50 ~ 70 DEG C, and power is 200 ~ 600W, and the number of times of extraction is 2 ~ 3 times, and each extraction time is 50 ~ 70min.
Further, the dosage form of step (2) described medicine is oral liquid, tablet or capsule.
The invention has the beneficial effects as follows:
(1) medicine of improving water flood of the present invention, its raw material all has the function of definite relieving insomnia symptom, improving water flood quality, adjustment sleep rhythm, has the effect of good improving water flood.
(2) medicine of improving water flood of the present invention, use safety, occurs without any untoward reaction.
(3) preparation method of the present invention is simple, and production degree is high, constant product quality, reliable, is applicable to large-scale production.
Detailed description of the invention
Be described principle of the present invention and feature below in conjunction with specific embodiment, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1:
A medicine for improving water flood, comprises the raw material of following weight: Radix Rhodiolae 10kg, Fructus Schisandrae Chinensis 20kg, Radix Polygoni Multiflori 5kg, Fructus Hippophae 15kg, Semen Nelumbinis 10kg, Radix Ophiopogonis 9kg, Ganoderma 4kg, Radix Glycyrrhizae 9kg, Caulis Polygoni Multiflori 5kg, Radix Scrophulariae 5kg and Radix Salviae Miltiorrhizae 1kg.
A preparation method for the medicine of improving water flood, comprises the steps:
(1) take the raw material of following weight: Radix Rhodiolae 10kg, Fructus Schisandrae Chinensis 20kg, Radix Polygoni Multiflori 5kg, Fructus Hippophae 15kg, Semen Nelumbinis 10kg, Radix Ophiopogonis 9kg, Ganoderma 4kg, Radix Glycyrrhizae 9kg, Caulis Polygoni Multiflori 5kg, Radix Scrophulariae 5kg and Radix Salviae Miltiorrhizae 1kg;
(2) raw material mixing step (1) taken, adds the water of 6 ~ 8 times amount, ultrasonic extraction, the temperature extracted is 50 DEG C, and power is 200W, and the number of times of extraction is 2 times, each extraction time is 70min, filter, filtrate is concentrated into the thick paste that relative density is 1.1 ~ 1.2, spraying dry to moisture content is 3%, obtain the active component of the medicine of described improving water flood, add pharmaceutically acceptable adjuvant, make oral liquid, obtain the medicine of described improving water flood.
Embodiment 2:
A medicine for improving water flood, comprises the raw material of following weight: Radix Rhodiolae 15kg, Fructus Schisandrae Chinensis 15kg, Radix Polygoni Multiflori 10kg, Fructus Hippophae 10kg, Semen Nelumbinis 15kg, Radix Ophiopogonis 6kg, Ganoderma 10kg, Radix Glycyrrhizae 6kg, Caulis Polygoni Multiflori 10kg, Radix Scrophulariae 3kg and Radix Salviae Miltiorrhizae 3kg.
A preparation method for the medicine of improving water flood, comprises the steps:
(1) take the raw material of following weight: Radix Rhodiolae 15kg, Fructus Schisandrae Chinensis 15kg, Radix Polygoni Multiflori 10kg, Fructus Hippophae 10kg, Semen Nelumbinis 15kg, Radix Ophiopogonis 6kg, Ganoderma 10kg, Radix Glycyrrhizae 6kg, Caulis Polygoni Multiflori 10kg, Radix Scrophulariae 3kg and Radix Salviae Miltiorrhizae 3kg;
(2) raw material mixing step (1) taken, adds the water of 6 ~ 8 times amount, ultrasonic extraction, the temperature extracted is 70 DEG C, and power is 400W, and the number of times of extraction is 2 times, each extraction time is 60min, filter, filtrate is concentrated into the thick paste that relative density is 1.1 ~ 1.2, spraying dry to moisture content is 4%, obtain the active component of the medicine of described improving water flood, add pharmaceutically acceptable adjuvant, make tablet, obtain the medicine of described improving water flood.
Embodiment 3:
A medicine for improving water flood, comprises the raw material of following weight: Radix Rhodiolae 20kg, Fructus Schisandrae Chinensis 10kg, Radix Polygoni Multiflori 15kg, Fructus Hippophae 5kg, Semen Nelumbinis 20kg, Radix Ophiopogonis 3kg, Ganoderma 16kg, Radix Glycyrrhizae 3kg, Caulis Polygoni Multiflori 15kg, Radix Scrophulariae 1kg and Radix Salviae Miltiorrhizae 5kg.
A preparation method for the medicine of improving water flood, comprises the steps:
(1) take the raw material of following weight: Radix Rhodiolae 20kg, Fructus Schisandrae Chinensis 10kg, Radix Polygoni Multiflori 15kg, Fructus Hippophae 5kg, Semen Nelumbinis 20kg, Radix Ophiopogonis 3kg, Ganoderma 16kg, Radix Glycyrrhizae 3kg, Caulis Polygoni Multiflori 15kg, Radix Scrophulariae 1kg and Radix Salviae Miltiorrhizae 5kg;
(2) raw material mixing step (1) taken, adds the water of 6 ~ 8 times amount, ultrasonic extraction, the temperature extracted is 50 DEG C, and power is 600W, and the number of times of extraction is 3 times, each extraction time is 50min, filter, filtrate is concentrated into the thick paste that relative density is 1.1 ~ 1.2, spraying dry to moisture content is 5%, obtain the active component of the medicine of described improving water flood, add pharmaceutically acceptable adjuvant, make capsule, obtain the medicine of described improving water flood.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. the medicine of an improving water flood, it is characterized in that, comprise the raw material of following parts by weight: Radix Rhodiolae 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Radix Polygoni Multiflori 5 ~ 15 parts, Fructus Hippophae 5 ~ 15 parts, 10 ~ 20 parts, Semen Nelumbinis, Radix Ophiopogonis 3 ~ 9 parts, Ganoderma 4 ~ 16 parts, 3 ~ 9 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 5 ~ 15 parts, Radix Scrophulariae 1 ~ 5 part and Radix Salviae Miltiorrhizae 1 ~ 5 part.
2. the medicine of a kind of improving water flood according to claim 1, it is characterized in that, comprise the raw material of following parts by weight: Radix Rhodiolae 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Polygoni Multiflori 10 parts, Fructus Hippophae 10 parts, 15 parts, Semen Nelumbinis, Radix Ophiopogonis 6 parts, Ganoderma 10 parts, 6 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 10 parts, Radix Scrophulariae 3 parts and Radix Salviae Miltiorrhizae 3 parts.
3. a preparation method for the medicine of improving water flood, is characterized in that, comprises the steps:
(1) raw material of following parts by weight is taken: Radix Rhodiolae 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Radix Polygoni Multiflori 5 ~ 15 parts, Fructus Hippophae 5 ~ 15 parts, 10 ~ 20 parts, Semen Nelumbinis, Radix Ophiopogonis 3 ~ 9 parts, Ganoderma 4 ~ 16 parts, 3 ~ 9 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 5 ~ 15 parts, Radix Scrophulariae 1 ~ 5 part and Radix Salviae Miltiorrhizae 1 ~ 5 part;
(2) raw material mixing step (1) taken, add the water of 6 ~ 8 times amount, after ultrasonic extraction, filter, filtrate is concentrated into the thick paste that relative density is 1.1 ~ 1.2, spraying dry is 3 ~ 5% to moisture content, obtains the active component of the medicine of described improving water flood, add pharmaceutically acceptable adjuvant, obtain the medicine of described improving water flood.
4. the preparation method of the medicine of a kind of improving water flood according to claim 3, it is characterized in that, the parts by weight of step (1) described raw material are: Radix Rhodiolae 15 parts, Fructus Schisandrae Chinensis 15 parts, Radix Polygoni Multiflori 10 parts, Fructus Hippophae 10 parts, 15 parts, Semen Nelumbinis, Radix Ophiopogonis 6 parts, Ganoderma 10 parts, 6 parts, Radix Glycyrrhizae, Caulis Polygoni Multiflori 10 parts, Radix Scrophulariae 3 parts and Radix Salviae Miltiorrhizae 3 parts.
5. the preparation method of the medicine of a kind of improving water flood according to claim 3, it is characterized in that, the temperature of step (2) described ultrasonic extraction is 50 ~ 70 DEG C, and power is 200 ~ 600W, the number of times extracted is 2 ~ 3 times, and each extraction time is 50 ~ 70min.
6. the preparation method of the medicine of a kind of improving water flood according to claim 3, is characterized in that, the dosage form of step (2) described medicine is oral liquid, tablet or capsule.
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| CN201510565715.6A CN105125847A (en) | 2015-09-08 | 2015-09-08 | Sleep improvement medicine and preparation method thereof |
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| CN201510565715.6A CN105125847A (en) | 2015-09-08 | 2015-09-08 | Sleep improvement medicine and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963272A (en) * | 2016-03-16 | 2016-09-28 | 安徽珠峰生物科技有限公司 | A healthcare capsule improving sleep |
| CN106389822A (en) * | 2016-10-27 | 2017-02-15 | 何本科 | Sleep-improving medicine and preparation method thereof |
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| JPS6212719A (en) * | 1985-07-10 | 1987-01-21 | Yasahiro Morita | Production of ym reishi |
| CN104056040A (en) * | 2014-06-28 | 2014-09-24 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine preparation for treating insomnia |
-
2015
- 2015-09-08 CN CN201510565715.6A patent/CN105125847A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6212719A (en) * | 1985-07-10 | 1987-01-21 | Yasahiro Morita | Production of ym reishi |
| CN104056040A (en) * | 2014-06-28 | 2014-09-24 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine preparation for treating insomnia |
Non-Patent Citations (2)
| Title |
|---|
| 易磊等: "《中国秘方大全》", 31 May 2013, 上海科学技术出版社 * |
| 郑曙峰等: "安神助眠汤治疗失眠43例", 《实用中医内科杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963272A (en) * | 2016-03-16 | 2016-09-28 | 安徽珠峰生物科技有限公司 | A healthcare capsule improving sleep |
| CN106389822A (en) * | 2016-10-27 | 2017-02-15 | 何本科 | Sleep-improving medicine and preparation method thereof |
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