CN105101990B - 胰岛素分泌多肽 - Google Patents

胰岛素分泌多肽 Download PDF

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Publication number
CN105101990B
CN105101990B CN201480019420.2A CN201480019420A CN105101990B CN 105101990 B CN105101990 B CN 105101990B CN 201480019420 A CN201480019420 A CN 201480019420A CN 105101990 B CN105101990 B CN 105101990B
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China
Prior art keywords
polypeptide
crrl
isp
seq
amino acid
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201480019420.2A
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English (en)
Chinese (zh)
Other versions
CN105101990A (zh
Inventor
H·H·陈
J·C·小伯内特
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Mayo Clinic in Florida
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Mayo Clinic in Florida
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Publication of CN105101990A publication Critical patent/CN105101990A/zh
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Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201480019420.2A 2013-02-15 2014-02-13 胰岛素分泌多肽 Expired - Fee Related CN105101990B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361765276P 2013-02-15 2013-02-15
US61/765,276 2013-02-15
PCT/US2014/016244 WO2014127120A1 (en) 2013-02-15 2014-02-13 Insulin secreting polypeptides

Publications (2)

Publication Number Publication Date
CN105101990A CN105101990A (zh) 2015-11-25
CN105101990B true CN105101990B (zh) 2017-12-22

Family

ID=51354543

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480019420.2A Expired - Fee Related CN105101990B (zh) 2013-02-15 2014-02-13 胰岛素分泌多肽

Country Status (6)

Country Link
US (2) US9938334B2 (enExample)
EP (1) EP2956160B1 (enExample)
JP (1) JP6480872B2 (enExample)
CN (1) CN105101990B (enExample)
DK (1) DK2956160T3 (enExample)
WO (1) WO2014127120A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2751136B1 (en) 2011-08-30 2017-10-18 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
WO2013103896A1 (en) 2012-01-06 2013-07-11 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
EP3296746A1 (en) * 2016-09-20 2018-03-21 Université de Bourgogne In vitro method for diagnosing at early stage intestinal ischemia
US12077561B2 (en) 2022-11-02 2024-09-03 Novo Nordisk A/S CNP compounds
WO2025235379A1 (en) * 2024-05-06 2025-11-13 Mayo Foundation For Medical Education And Research Polypeptides having natriuretic and insulin-secreting actions, and methods for their use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1219134A (zh) * 1997-02-05 1999-06-09 三得利株式会社 心肌肥大性心脏病治疗用药物组合物
WO2007017892A2 (en) * 2005-05-05 2007-02-15 Cadila Healthcare Limited Novel compounds as glp-i agonists
WO2010041612A1 (en) * 2008-10-06 2010-04-15 Canon Kabushiki Kaisha Communication apparatus, control method of communication apparatus, computer program, and storage medium
WO2010125079A2 (en) * 2009-05-01 2010-11-04 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757048A (en) 1985-11-05 1988-07-12 Biotechnology Research Associates J.V. Synthetic analogs of atrial natriuretic peptides
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US8076288B2 (en) * 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
EP2330124B1 (en) 2005-08-11 2015-02-25 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
US20100041612A1 (en) 2005-09-08 2010-02-18 Martin Beinborn Fragments of the Glucagon-Like Peptide-1 and Uses Thereof
CA2800389A1 (en) * 2006-04-20 2007-11-01 Amgen Inc. Glp-1 compounds
EP2080812A1 (en) * 2008-01-18 2009-07-22 Transmedi SA Compositions and methods of detecting post-stop peptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1219134A (zh) * 1997-02-05 1999-06-09 三得利株式会社 心肌肥大性心脏病治疗用药物组合物
WO2007017892A2 (en) * 2005-05-05 2007-02-15 Cadila Healthcare Limited Novel compounds as glp-i agonists
WO2010041612A1 (en) * 2008-10-06 2010-04-15 Canon Kabushiki Kaisha Communication apparatus, control method of communication apparatus, computer program, and storage medium
WO2010125079A2 (en) * 2009-05-01 2010-11-04 F. Hoffmann-La Roche Ag Insulinotropic peptide synthesis using solid and solution phase combination techniques

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor》;Christina Rye Underwood等;《THE JOURNAL OF BIOLOGICAL CHEMISTRY》;20100101;第285卷(第1期);第723–730页 *

Also Published As

Publication number Publication date
US10336803B2 (en) 2019-07-02
JP6480872B2 (ja) 2019-03-13
US20150368312A1 (en) 2015-12-24
CN105101990A (zh) 2015-11-25
US9938334B2 (en) 2018-04-10
DK2956160T3 (en) 2018-08-06
EP2956160B1 (en) 2018-04-25
JP2016508517A (ja) 2016-03-22
EP2956160A4 (en) 2016-08-03
WO2014127120A1 (en) 2014-08-21
US20180273600A1 (en) 2018-09-27
EP2956160A1 (en) 2015-12-23

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Granted publication date: 20171222

Termination date: 20210213