CN105078443B - Flush type nerve signal recording device and its application method - Google Patents
Flush type nerve signal recording device and its application method Download PDFInfo
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- CN105078443B CN105078443B CN201510399740.1A CN201510399740A CN105078443B CN 105078443 B CN105078443 B CN 105078443B CN 201510399740 A CN201510399740 A CN 201510399740A CN 105078443 B CN105078443 B CN 105078443B
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- electrode
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- protective case
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Abstract
It is a kind of flush type nerve signal recording device and its application method the present invention relates to nerve signal recording device technical field；The flush type nerve signal recording device, including interconnecting piece, neural insulation protective case, horizontal direction first electrode and second electrode；Neural insulation protective case is fixedly mounted on the right part of interconnecting piece, the top of neural insulation protective case it is axially disposed have be open in the front-back direction, the subcutaneous fixation hole of vertical direction is provided in interconnecting piece.The invention avoids nerve cords to contact shakiness with first electrode and second electrode, cause artifact to increase, while considerably reducing the labor intensity of experimenter, nerve cord is avoided passively to elongate, cause violence injuring nerve dry, make nerve cord exposure for a long time in air, leading to nerve cord, dry and temperature reduces rapidly, and neural activity reduction is caused to even result in neural death, cause the failure of an experiment, have the characteristics that safe and reliable, facilitates operation, improve success rate.
Description
Technical field
The present invention relates to nerve signal recording device technical field, it is a kind of flush type nerve signal recording device and its makes
Use method.
Background technique
Currently, after nerve cord signal record needs experimenter to separate nerve cord in zoopery, hand pen type nerve signal electricity
Nerve cord is chosen in pole records nerve signal outside animal body.There are three types of drawbacks for this device: 1. experimenter's hand pen type nerves letter
Number electrode, this results in causing tracer signal artifact to increase due to electrode and nerve signal poor contact, and interference increases；2. due to
Hand nerve probe electrode need to exposure be external for a long time by nerve cord, leads to dry and temperature reduction rapidly in nerve cord exposure air,
Neural activity reduction is caused to even result in neural death, the failure of an experiment；3. causing since passive exposure is external for a long time for nerve cord
Neural stem structure passively elongates, and nerve cord structure violence is caused to damage；4. due to needing experimenter's hand pen type neural recording electrode,
Therefore limited experimenter's physical strength, increase experimenter's labor intensity.
Summary of the invention
The present invention provides a kind of flush type nerve signal recording device and its application methods, overcome the above-mentioned prior art
Deficiency, big, large labor intensity that there are signal artifacts when can effectively solve existing nerve cord signal record, neural stem structure are easy
The problem of violence damage even results in neural death.
Technical solution of the present invention first is that being realized by following measures: a kind of flush type nerve signal record dress
Set, including interconnecting piece, neural insulation protective case, horizontal direction first electrode and second electrode；Neural insulation protective case is fixed
Be mounted on the right part of interconnecting piece, the top of neural insulation protective case it is axially disposed have be open in the front-back direction, in interconnecting piece
It is inside provided with the subcutaneous fixation hole of vertical direction, is respectively separated in the middle part of interconnecting piece and is fixedly installed with first electrode and the second electricity
The right end of pole, first electrode and second electrode is located in neural insulation protective case.
Here is further optimization or/and improvement of one of the above technical solutions of the invention:
The above-mentioned right part in interconnecting piece is provided with opening towards right arc groove, and the left part of neural insulation protective case is fixedly mounted
In the arc groove of interconnecting piece.
Above-mentioned neural insulation protective case is microcellular rubber set.
Above-mentioned to have nerve signal recorder on the outside of interconnecting piece, first electrode and second electrode are remembered with nerve signal respectively
The signal input part of record instrument is electrically connected.
The height of above-mentioned first electrode and second electrode is equal.
Above-mentioned first electrode and second electrode are silver wire electrode.
Technical solution of the present invention second is that being realized by following measures: a kind of flush type nerve signal recording device
Application method, carry out in the steps below: the first step, anaesthesia experiment animal after art area preserved skin, cut skin, and separation is intended to record
Neural dry doubling exposure；Second step opens the opening on neural insulation protective case, the nerve cord of separator well is passed through neural insulation
Opening sleeve on protective case enters in neural insulating protective sleeve, is tightly attached to first electrode and second electrode on nerve cord；Third step,
Single line is penetrated in the subcutaneous fixation hole of interconnecting piece, the both ends of line are bypassed into interconnecting piece and neural insulation protective case respectively and is beaten
Knot is closed the opening on neural insulation protective case；4th step, sews up a wound, and makes first electrode and second electrode after sewing up a wound
The other end expose wound outside, then by expose wound outside first electrode and second electrode the other end respectively with nerve signal
The signal input part of recorder is electrically connected, start recording nerve cord signal.
Here is further optimization or/and improvement of the technical scheme ii of the invention:
Above-mentioned line is to admire silk thread.
It is above-mentioned that flush type nerve signal recording device is soaked in SHENJING YINGYANG YE or in physiological saline before surgery.
Above-mentioned experimental animal can pig or dog or rabbit.
The invention avoids nerve cords to contact shakiness with first electrode and second electrode, causes artifact to increase, while substantially
Degree reduces the labor intensity of experimenter, and nerve cord is avoided passively to elongate, and causes violence injuring nerve dry, makes nerve cord for a long time
In air, leading to nerve cord, dry and temperature reduces rapidly for exposure, causes neural activity reduction to even result in neural death, makes
At the failure of an experiment, have the characteristics that safe and reliable, facilitates operation, improve success rate.
Detailed description of the invention
Attached drawing 1 is schematic perspective view of the present invention without nerve signal recorder.
Coding in attached drawing is respectively as follows: 1 for interconnecting piece, and 2 be neural insulation protective case, and 3 be first electrode, and 4 be the second electricity
Pole, 5 be opening, and 6 be subcutaneous fixation hole.
Specific embodiment
The present invention is not limited by the following examples, can determine according to the technique and scheme of the present invention with actual conditions specific
Embodiment.
In the present invention, for ease of description, the description of the relative positional relationship of each component is according to Figure of description 1
Butut mode be described, such as: front, rear, top, and bottom, left and right positional relationship be the cloth according to Figure of description 1
Figure direction determines.
Below with reference to examples and drawings, the invention will be further described:
Embodiment 1, as shown in Fig. 1, the flush type nerve signal recording device include interconnecting piece 1, neural insulation protection
The first electrode 3 and second electrode 4 of set 2, horizontal direction；Neural insulation protective case 2 is fixedly mounted on the right part of interconnecting piece 1,
The top of neural insulation protective case 2 is axially disposed to be had and is open 5 in the front-back direction, is provided with vertical direction in interconnecting piece 1
Subcutaneous fixation hole 6, is respectively separated at the middle part of interconnecting piece 1 and is fixedly installed with first electrode 3 and second electrode 4,3 He of first electrode
The right end of second electrode 4 is located in neural insulation protective case 2.In this way, after neural insulation protective case 2 is convenient for being inserted in nerve cord
It can be very good to form nerve cord and surrounding tissue and insulate, realize and effectively avoid doing after relatively closed space, embedment are subcutaneous
It disturbs.
Above-described embodiment 1 can be made further optimization and/or improvements according to actual needs:
As shown in Fig. 1, opening 5 is provided with towards right arc groove in the right part of interconnecting piece 1, neural insulation protective case 2
Left part is fixedly mounted in the arc groove of interconnecting piece 1.In this way, arc groove is convenient for the installation of neural insulation protective case 2.
As needed, neural insulation protective case 2 is microcellular rubber set.In this way, convenient for well by nerve cord and surrounding group
It knits to form insulation.
As needed, have a nerve signal recorder in the outside of interconnecting piece 1, first electrode 3 and second electrode 4 respectively with mind
Signal input part through signal recorder is electrically connected.In this way, convenient for record nerve cord signal in real time.
As shown in Fig. 1, first electrode 3 is equal with the height of second electrode 4.In this way, being convenient for first electrode 3 and second
Electrode 4 can be tightly attached on nerve cord, avoid nerve cord and first electrode 3 and second electrode 4 contacts shakiness, artifact is caused to increase
Greatly, while the labor intensity of experimenter is considerably reduced.
As needed, first electrode 3 and second electrode 4 are silver wire electrode.
Embodiment 2, as shown in Fig. 1, the application method of the flush type nerve signal recording device, in the steps below into
Row: the first step, anaesthesia experiment animal after art area preserved skin, cut skin, separate the neural dry doubling to be recorded exposure；Second step is beaten
The opening 5 on neural insulation protective case 2 is opened, the nerve cord of separator well is superb by 5 sets of opening on neural insulation protective case 2
Through being tightly attached to first electrode 3 and second electrode 4 on nerve cord；Third step, in the subcutaneous solid of interconnecting piece 1
Determine to penetrate single line in hole 6, the both ends of line, which are bypassed interconnecting piece 1 and neural insulation protective case 2 respectively and knotted, makes neural insulation
Opening 5 on protective case 2 is closed；4th step, sews up a wound, and the other end of first electrode 3 and second electrode 4 is made after sewing up a wound
Expose wound outside, then by expose wound outside first electrode 3 and second electrode 4 the other end respectively with nerve signal recorder
Signal input part be electrically connected, start recording nerve cord signal.In this way, being recorded using flush type nerve signal of the present invention
Existing pen type nerve signal electrode can be replaced after device completely, when avoiding existing pen type nerve signal electrode is hand-held from recording nerve signal
It causes nerve to contact shakiness with electrode, causes artifact to increase, while considerably reducing the labor intensity of experimenter, avoid nerve
It is dry passive to elongate, cause violence injuring nerve dry, make nerve cord exposure for a long time in air, cause nerve cord dry rapidly and
Temperature reduces, and causes neural activity reduction to even result in neural death, causes the failure of an experiment, has the characteristics that safe and reliable, side
Operation, improve success rate.In third step, when using line by 5 closure of opening, it can not be closed tension, prevent from causing nerve
Do repressive damage.
Above-described embodiment 2 can be made further optimization and/or improvements according to actual needs:
As needed, line is to admire silk thread.As needed, flush type nerve signal recording device is soaked in mind before surgery
Through in nutrient solution or in physiological saline.In this way, can keep nerve dry active when use.
As needed, experimental animal can be pig or dog or rabbit.
The above technical features constitute embodiments of the present invention, can basis with stronger adaptability and implementation result
Actual needs increases and decreases non-essential technical characteristic, to meet the needs of different situations.
Claims (1)
1. a kind of flush type nerve signal recording device, it is characterised in that including interconnecting piece, neural insulation protective case, horizontal direction
First electrode and second electrode；Neural insulation protective case is fixedly mounted on the right part of interconnecting piece, in neural insulation protective case
Top is axially disposed to be had and is open in the front-back direction, the subcutaneous fixation hole of vertical direction is provided in interconnecting piece, in interconnecting piece
Middle part be respectively separated and be fixedly installed with first electrode and second electrode, the right end of first electrode and second electrode is located at mind
Through in insulating protective sleeve；Wherein: the right part of interconnecting piece is provided with opening towards right arc groove, and the left part of neural insulation protective case is solid
Dingan County is in the arc groove of interconnecting piece；Neural insulation protective case is microcellular rubber set；There is nerve signal note on the outside of interconnecting piece
Instrument is recorded, the signal input part of first electrode and second electrode respectively with nerve signal recorder is electrically connected；First electrode
It is equal with the height of second electrode；First electrode and second electrode are silver wire electrode.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510399740.1A CN105078443B (en) | 2015-07-09 | 2015-07-09 | Flush type nerve signal recording device and its application method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510399740.1A CN105078443B (en) | 2015-07-09 | 2015-07-09 | Flush type nerve signal recording device and its application method |
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| CN105078443A CN105078443A (en) | 2015-11-25 |
| CN105078443B true CN105078443B (en) | 2019-01-11 |
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Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4852573A (en) * | 1987-12-04 | 1989-08-01 | Kennedy Philip R | Implantable neural electrode |
| WO2008019483A1 (en) * | 2006-08-14 | 2008-02-21 | Med-El Elektro-Medizinische Geräte Gesellschaft M.B.H. | Implantable medical cuff with electrode array |
| US20080172116A1 (en) * | 2007-01-16 | 2008-07-17 | Ndi Medical, Inc. | Devices, systems, and methods employing a molded nerve cuff electrode |
| CN101306225A (en) * | 2007-09-30 | 2008-11-19 | 中国人民解放军第四军医大学 | Embedded nerve electrode for recovering eyes-closed function and control system |
| CN201333033Y (en) * | 2009-01-16 | 2009-10-28 | 中国人民解放军第四军医大学 | Implantable stimulating and guiding device for action potential of animal nerves |
| US20100168831A1 (en) * | 2008-12-30 | 2010-07-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Implantable clip-on micro-cuff electrode for functional stimulation and bio-potential recording |
| CN103638596A (en) * | 2013-12-11 | 2014-03-19 | 上海交通大学医学院附属仁济医院 | Animal vagus nerve stimulation electrode and preparation method thereof |
| CN203647859U (en) * | 2013-12-11 | 2014-06-18 | 上海交通大学医学院附属仁济医院 | Dedicated vagus nerve stimulation electrodes applied to animals |
| CN103976727A (en) * | 2014-05-22 | 2014-08-13 | 侯月梅 | Recording method for neck nerve signals |
| CN103989467A (en) * | 2014-05-22 | 2014-08-20 | 侯月梅 | Animal neck neural signal continuous recording model and recording method |
-
2015
- 2015-07-09 CN CN201510399740.1A patent/CN105078443B/en not_active Expired - Fee Related
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4852573A (en) * | 1987-12-04 | 1989-08-01 | Kennedy Philip R | Implantable neural electrode |
| WO2008019483A1 (en) * | 2006-08-14 | 2008-02-21 | Med-El Elektro-Medizinische Geräte Gesellschaft M.B.H. | Implantable medical cuff with electrode array |
| US20080172116A1 (en) * | 2007-01-16 | 2008-07-17 | Ndi Medical, Inc. | Devices, systems, and methods employing a molded nerve cuff electrode |
| CN101306225A (en) * | 2007-09-30 | 2008-11-19 | 中国人民解放军第四军医大学 | Embedded nerve electrode for recovering eyes-closed function and control system |
| US20100168831A1 (en) * | 2008-12-30 | 2010-07-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Implantable clip-on micro-cuff electrode for functional stimulation and bio-potential recording |
| CN201333033Y (en) * | 2009-01-16 | 2009-10-28 | 中国人民解放军第四军医大学 | Implantable stimulating and guiding device for action potential of animal nerves |
| CN103638596A (en) * | 2013-12-11 | 2014-03-19 | 上海交通大学医学院附属仁济医院 | Animal vagus nerve stimulation electrode and preparation method thereof |
| CN203647859U (en) * | 2013-12-11 | 2014-06-18 | 上海交通大学医学院附属仁济医院 | Dedicated vagus nerve stimulation electrodes applied to animals |
| CN103976727A (en) * | 2014-05-22 | 2014-08-13 | 侯月梅 | Recording method for neck nerve signals |
| CN103989467A (en) * | 2014-05-22 | 2014-08-20 | 侯月梅 | Animal neck neural signal continuous recording model and recording method |
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| CN105078443A (en) | 2015-11-25 |
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Granted publication date: 20190111 Termination date: 20200709 |