CN105056859A - Rotary biochemical reaction box - Google Patents

Rotary biochemical reaction box Download PDF

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Publication number
CN105056859A
CN105056859A CN201510465501.1A CN201510465501A CN105056859A CN 105056859 A CN105056859 A CN 105056859A CN 201510465501 A CN201510465501 A CN 201510465501A CN 105056859 A CN105056859 A CN 105056859A
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China
Prior art keywords
casing
biochemical reaction
rotary
rotating shaft
sample
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CN201510465501.1A
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CN105056859B (en
Inventor
李强
季更生
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Zhangjiagang Industrial Technology Research Institute of Jiangsu University of Science and Technology
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Zhangjiagang Industrial Technology Research Institute of Jiangsu University of Science and Technology
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Publication of CN105056859A publication Critical patent/CN105056859A/en
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Abstract

The present invention relates to a rotary biochemical reaction box, which comprises: a box body, wherein the box body is provided with a box door; a rotating assembly, wherein the rotating assembly comprises a rotating drive device and a rotating shaft, and the rotating shaft is arranged inside the box body and rotates under the driving effect of the rotating drive device; a sample fixation assembly, wherein the sample fixation assembly is arranged on the rotating shaft, can rotate along with the rotating shaft, and is used for fixing a sample; and a light irradiating assembly, wherein the light irradiating assembly is arranged inside the box body and is used for providing light irradiating. According to the present invention, the rotating assembly is arranged to drive the sample to rotate, such that the sample internal substances in the reaction tube are mixed and stirrer so as to prevent the sample from layering, and the reactant positioned inside can move to the reaction tube surface layer during the rotating to completely receive the light irradiation so as to uniformly carry out the biochemical reaction and improve the experiment result; and the equipment has characteristics of simple and convenient operation, concurrent treatment of multiple groups of samples, and high treatment capacity.

Description

A kind of rotary biochemical reaction case
Technical field
The present invention relates to a kind of rotary biochemical reaction case, belong to biochemical industry consersion unit field.
Background technology
Under lab, in order to accurately control biochemical reaction, usually biochemical reactant is needed to insert in the reaction chamber of constant temperature and pressure, as Chinese patent literature CN104338501A discloses a kind of photochemical reaction case of tunable optical, comprise: casing, specimen holder and control system, described casing comprises base plate, cover plate, left plate, right plate, front side board and back side panel; The inner surface of described left plate and right plate is provided with light source; Described front side board and back side panel are provided with fan; Described specimen holder is fixed on described base plate, and parallels with described left plate; Described specimen holder is provided with temperature sensor; Described control system comprises temperature control module, control module and time block, and the input of described temperature control module is connected with described temperature sensor and fan respectively with output; Described control module is connected with light source respectively with time block.The intensity of the control module adjustable light sources in this photochemical reaction case, temperature sensor and temperature control module can regulate the temperature inside the box, time block be used for reach arrange time, open or close light source.But be fixed on base plate owing to placing the specimen holder of sample, when sample is liquid, gravitate sample interior there will be the phenomenon of layering, if also have solid in liquid reactants, then lamination can be even more serious, this causes sample interior species distribution unbalanced, and then makes biochemical reaction uneven, affects experiment effect.If when sample is solid, so light penetration is limited in one's ability, light can only be irradiated to sample surfaces, and sample interior cannot be subject to illumination effect, and biochemical reaction is also uneven.
Summary of the invention
For this reason, the invention reside in and solve the biochemical reaction cabinet mesophytization of prior art and react uneven problem, thus propose a kind ofly sample can be made fully to be subject to light irradiate and biochemical reaction cabinet mesophytization reacted evenly and then improves the biochemical reaction cabinet of experiment effect.
For solving the problems of the technologies described above, the present invention proposes a kind of rotary biochemical reaction case, comprises
Casing, described casing is provided with openable chamber door;
Light radiation module, described smooth radiation module is arranged in described casing, for providing light irradiation;
Described rotary biochemical reaction cabinet also comprises rotary components,
Described rotary components comprises rotating driving device and rotating shaft, and described rotating shaft is arranged on described box house and rotates under the driving effect of described rotating driving device;
Sample fixation kit, described sample fixation kit is arranged in described rotating shaft can with described axis of rotation, for fixed sample.
Rotary biochemical reaction cabinet of the present invention, described sample fixation kit comprises installed part and installing plate, and described installed part to be arranged in described rotating shaft and vertical with described shaft axis; Described installing plate to be fixed on described installed part and to have at least one through hole for fixed sample.
Rotary biochemical reaction cabinet of the present invention, the plate face of described installing plate and the axis of described rotating shaft are 20 ° of-70 ° of angles.
Rotary biochemical reaction cabinet of the present invention, described installing plate is fixed on described installed part by angle adjusting mechanism, the angle that described angle adjusting mechanism can regulate the plate face of described installing plate and the axis of rotating shaft to be formed.
Rotary biochemical reaction cabinet of the present invention, described biochemical reaction cabinet also comprises temperature-controlling component, described temperature-controlling component comprises the ventilation unit for making described casing inner air and outer air circulate be arranged on described box body wall, and/or for the heating combined equipment that improves temperature in described casing and/or the refrigerating plant for reducing temperature in described casing.
Rotary biochemical reaction cabinet of the present invention, also comprise Control Component and temperature sensor, described temperature sensor is for measuring the temperature in described casing, and the temperature value recorded is passed to described Control Component, described Control Component controls described ventilation unit or heating combined equipment or refrigerating plant according to temperature value and closes or start.
Rotary biochemical reaction cabinet of the present invention, described refrigerating plant is arranged through the rear wall of casing, described refrigerating plant comprises the aerofoil fan being positioned at box inside, be arranged on the second radiator on described aerofoil fan, be positioned at the first radiator outside casing, semiconductor refrigerating part is provided with between described second radiator and described first radiator, described aerofoil fan makes air in described casing flow through described second radiator, heat in air gives described semiconductor refrigerating part through described second heat sink, described semiconductor refrigerating part again by heat by described first heat sink radiates to outside described casing.
Rotary biochemical reaction cabinet of the present invention, described Control Component is also connected with described rotating driving device and/or described smooth radiation module, for described control rotating driving device start/stop and control its rotating speed, and control On/Off and the intensity of illumination of described smooth radiation module.
Rotary biochemical reaction cabinet of the present invention, described biochemical reaction cabinet comprises and is arranged in described casing top inner wall and caves inward to form the space of installing described smooth radiation module, fluorescent lamp and/or ultraviolet lamp is provided with in described installing space, and described installing space opening part is provided with lampshade, so that described installing space is sealed.
Rotary biochemical reaction cabinet of the present invention, described cabinet wall has the specular layer for reflection ray.
Technique scheme of the present invention has the following advantages compared to existing technology:
First, rotary biochemical reaction cabinet of the present invention drives sample to rotate by arranging rotary components, the material of sample interior is made fully mixing to occur and stir, prevent sample generation layering, and the material being positioned at inside can move to top layer and fully receive light irradiation when rotating, make biochemical reaction carry out more even, improve experiment effect.
Secondly, rotary biochemical reaction cabinet of the present invention has certain angle due to the plate face of installing plate and rotating shaft, so the test tube that sample is housed is when being installed on installing plate, also forms an angle with the axis shape of rotating shaft.When the spindle is rotated, invisible spectro sample is not only around axis of rotation, and test tube also can turned upside down, invisible spectro sample is obtained and stirs fully, improve the uniformity of biochemical reaction further.
In addition, in rotary biochemical reaction cabinet of the present invention, semiconductor refrigerating part volume is little, mechanical running part, noiselessness in work, and aneroid, gas working media are free from environmental pollution, and cooling parameters is not by direction in space and gravity effect; By regulating the size of operating current, conveniently adjusted cooling rate, refrigerating speed is fast, long service life, and is easy to control.And arrange semiconductor refrigerating part to make only heat exchange to occur outward with casing in casing, material (gas) does not occur and exchanges, ensure that the sealing in casing.Thus strictly can control the condition such as temperature, pressure in casing, make the carrying out of biochemical reaction not be subject to the impact of external environment condition.
Accompanying drawing explanation
In order to make content of the present invention be more likely to be clearly understood, below according to a particular embodiment of the invention and by reference to the accompanying drawings, the present invention is further detailed explanation, wherein
Fig. 1 is the front sectional view of the embodiment of the present invention;
Fig. 2 is that sectional view is looked on the right side of the embodiment of the present invention;
Fig. 3 is the rearview of the embodiment of the present invention;
Fig. 4 is the top view of the embodiment of the present invention;
Fig. 5 is the right view of the embodiment of the present invention.
In figure, Reference numeral is expressed as: 1-casing; 2-chamber door; 3-control panel; 6-installing plate; 7-rotating driving device; 8-rotating shaft; Plate after 11-; 12-deflector; 13-specular layer; 14-sealing strip; 15-bearing; 16-side plate; 17-switch; 18-footing; 20-installed part; 21-first radiator; 22-fluorescent lamp; 23-thermal insulation board; 24-ultraviolet lamp; 25-aerofoil fan; 26-lampshade; 27-second radiator; 28-semiconductor chilling plate; 29-conducting strip; 71-shaft coupling; 72-sealing ring; 73-seal cover; 81-installation cavity; 91-binding post; 92-hinge.
Detailed description of the invention
Below in conjunction with accompanying drawing, technical scheme of the present invention is described in detail.
Embodiment 1
The present embodiment provides a kind of rotary biochemical reaction case, as Fig. 1-5, comprises casing 1, the chamber door 2 that described casing 1 is provided with;
Light radiation module, described smooth radiation module is arranged in described casing 1, for providing light;
Also comprise rotary components, described rotary components comprises rotating driving device 7 and rotating shaft 8, and described rotating shaft 8 is arranged on described casing 1 inside and rotates under the driving effect of described rotating driving device 7;
Sample fixation kit, described sample fixation kit is arranged in described rotating shaft 8 and can rotates, for fixed sample with described rotating shaft 8.
Sample is driven to rotate by arranging rotary components, the material of sample is made mixing to occur and stir, prevent reaction tube inner sample generation layering, and the material being positioned at reaction tube inside can move to top layer and fully receive light irradiation when rotating, make biochemical reaction carry out more even, improve experiment effect.
Rotating shaft 8 one end is fixed on a sidewall of casing 1 by bearing 15, and the other end is connected with rotating driving device 7 by shaft coupling 71, and rotating driving device 7 is arranged in the installation cavity 81 outside casing 1.In order to enable the driving shaft of drive unit 7 be connected with the shaft coupling 71 in casing 1, casing 1 sidewall is provided with opening, and the seal cover 73 that opening part is provided with sealing ring 72 and fixes sealing ring 72 is to seal between the driving shaft of drive unit 7 and casing 1 sidewall.In order to ensure sealing, the contact surface between chamber door 2 and casing 1 is provided with sealing strip 14, with the gap between sealed container door 2 and casing 1.
The rotary biochemical reaction cabinet of the present embodiment, described sample fixation kit, comprise, be arranged in described rotating shaft 8 with the installed part 20 of described rotating shaft 8 axes normal and installing plate 6, installing plate 6 to be fixed on installed part 20 and to have at least one through hole for fixed sample.
In the rotary biochemical reaction cabinet of the present embodiment, the plate face of described installing plate 6 and the axis of rotating shaft 8 form the angle of arbitrary number of degrees in 20 °-70 °, are preferably formed the angle of 45 °.Because the plate face of described installing plate 6 and rotating shaft 8 have certain angle, so the test tube that sample is housed is when being installed on installing plate 6, also form an angle with the axis shape of rotating shaft 8.When rotating shaft 8 is rotated, invisible spectro sample is not only rotate around rotating shaft 8, and test tube also can turned upside down, invisible spectro sample is obtained and stirs fully, improve the uniformity of biochemical reaction further.
As a kind of embodiment of improvement, described installing plate 6 is fixed on described installed part 20 by angle adjusting mechanism, the angle that described angle adjusting mechanism can regulate the plate face of described installing plate 6 and the axis of rotating shaft 8 to be formed.
Angle adjusting mechanism can be such as the regular polygon spliced eye being arranged on installed part 20, installing plate 6 is provided with the regular polygon socket coordinated with polygon spliced eye, insert in regular polygon spliced eye by regular polygon socket with different angles, to realize the adjustment to the angle that the plate face of described installing plate 6 and the axis of rotating shaft 8 are formed, angle adjusting mechanism also can be other form.The angle regulating the plate face of installing plate 6 and the axis of rotating shaft 8 to be formed by arranging angle adjusting mechanism can obtain different mixed effects, to improve the adaptive faculty of biochemical reaction cabinet for different sample.
The rotary biochemical reaction cabinet of the present embodiment, also comprise temperature-controlling component, described temperature-controlling component comprises, for improving the heating combined equipment of temperature in casing 1, for reducing the refrigerating plant of temperature in casing 1.
The rotary biochemical reaction cabinet of the present embodiment, also comprise Control Component 3, and temperature sensor, described temperature sensor is for measuring temperature in casing 1, and the temperature value recorded is passed to Control Component 3, Control Component 3 controls heating combined equipment according to temperature value or refrigerating plant cuts out or starts.
As a rule, can produce heat when light radiation module is luminous and when biochemical reaction carries out, this heat can cause temperature in casing 1 to raise, and only has when the temperature of experiment condition is higher, just can consider to increase extra heating combined equipment.Heating combined equipment can be the heating resistor etc. being positioned at casing 1.The temperature sensor arranged can obtain the temperature value in casing 1 in real time, then this temperature value is sent to Control Component 3, Control Component 3 is by contrasting with desired temperature, when actual temperature value is higher than setting value, control refrigerating plant runs, when actual temperature value is lower than setting value, controls heating combined equipment and run, to make temperature constant.
The rotary biochemical reaction cabinet of the present embodiment, described refrigerating plant is arranged through the rear wall of casing 1, described refrigerating plant comprises, be positioned at the aerofoil fan 25 inside casing 1, be arranged on the second radiator 27 on described aerofoil fan 25, be positioned at the first radiator 21 outside casing 1, semiconductor refrigerating part 28 is provided with between described second radiator 27 and described first radiator 21, described aerofoil fan 25 makes air in casing 1 flow through the second radiator 27, heat in air passes to described semiconductor refrigerating part 28 through the second radiator 27, heat is dispersed into outside casing 1 by the first radiator 21 by described semiconductor refrigerating part 28 again.Between described aerofoil fan 25 and described first radiator 21, thermal insulation board 23 is set, described thermal insulation board 23 intermediary form has through hole, described semiconductor refrigerating part 28 is positioned at this through hole, described thermal insulation board 23 plays the effect of fixing described semiconductor refrigerating part 28, ensures that heat passes through perpendicular to direction, semiconductor refrigerating part 28 plate face.In order to improve heat-conducting effect further, be also provided with conducting strip 29 in the both sides, plate face of semiconductor refrigerating part 28 or side, conducting strip 29 makes semiconductor refrigerating part 28 contact respectively with the second radiator 27 with the first radiator 21.
Semiconductor refrigerating part 28 volume is little, mechanical running part, noiselessness in work, aneroid, gas working media, free from environmental pollution, and cooling parameters is not by direction in space and gravity effect; By regulating the size of operating current, conveniently adjusted cooling rate, refrigerating speed is fast, long service life, and is easy to control.And arrange semiconductor refrigerating part 28 to make only heat exchange to occur in casing 1 with outside casing 1, material (gas) does not occur and exchanges, ensure that the sealing in casing 1.Thus strictly can control the condition such as temperature, pressure in casing 1, make the carrying out of biochemical reaction not be subject to the impact of external environment condition.Time not high to sealing requirements, the ventilation unit for the such as fan making casing 1 inner air and outer air circulate also can be set on casing 1 wall, realize temperature by the circulation of air and control.
In addition, casing 1 inwall is also provided with the deflector 12 covering aerofoil fan 25 air flow inlet, deflector 12 is provided with some through holes, to make air dispersion.
The rotary biochemical reaction cabinet of the present embodiment, described Control Component 3 is also connected with described rotating driving device 7 and/or described smooth radiation module, for described control rotating driving device 7 start/stop and control its rotating speed, and control On/Off and the intensity of illumination of described smooth radiation module.
The antetheca arranged outside of installation cavity 81 has control panel 3.Control panel 3 there is control button, presses corresponding control button and just can control the start/stop of rotating driving device 7 and control rotating speed, control On/Off and the luminous intensity of light radiation module.
The rotary biochemical reaction cabinet of the present embodiment, described biochemical reaction cabinet comprises and is arranged in described casing 1 top inner wall and caves inward to form the space of installing described smooth radiation module, fluorescent lamp 22 and/or ultraviolet lamp 24 is provided with in described installing space, and described installing space opening part is provided with lampshade 26, so that described installing space is sealed.Certainly, when unnecessary, one of them of fluorescent lamp 22 and ultraviolet lamp 24 can be only set.
Light radiation module installing space seals by lampshade 26; make fluorescent lamp 22 and ultraviolet lamp 24 isolated with other space in casing 1; prevent experimenter from touching fluorescent lamp 22 and ultraviolet lamp 24, the safety of protection fluorescent lamp 22 and/or ultraviolet lamp 24 and experimenter.
The biochemical reaction cabinet of the present embodiment, casing 1 inwall has the specular layer 13 for reflection ray.
Specular layer 13 is for having the corrosion resistant plate of smooth finish surface.Specular layer 13 can the light that sends of reverberation radiation module, enables the distribution of light in casing 1 more even.
In the present embodiment, chamber door 2 is that " L shape " mounts cover on the upper wall and antetheca of casing 1, and chamber door 2 is fixed by hinge 92 and upper wall outer surface.The rear wall of casing 1 is provided with binding post 91 for being connected with power supply, and is mounted cover by rear plate 11.Casing 1 sidewall on be provided with side plate 16, opening after side plate 16 can opening installation chamber 81, is provided with switch 17, for controlling the on/off of the power supply of biochemical reaction cabinet entirety in installation cavity 81.The bottom of casing 1 is provided with footing 18.
Obviously, above-described embodiment is only for clearly example being described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of extending out or variation be still among the protection domain of the invention.

Claims (10)

1. a rotary biochemical reaction case, comprises
Casing (1), described casing (1) is provided with openable chamber door (2);
Light radiation module, described smooth radiation module is arranged in described casing (1), for providing light irradiation;
It is characterized in that,
Described rotary biochemical reaction cabinet also comprises rotary components,
Described rotary components comprises rotating driving device (7) and rotating shaft (8), and described rotating shaft (8) is arranged on described casing (1) inside and rotates under the driving effect of described rotating driving device (7);
Sample fixation kit, described sample fixation kit is arranged in described rotating shaft (8) and can rotates, for fixed sample with described rotating shaft (8).
2. rotary biochemical reaction case according to claim 1, is characterized in that,
Described sample fixation kit comprises installed part (20) and installing plate (6), described installed part (20) be arranged on described rotating shaft (8) upper and with described rotating shaft (8) axes normal; Described installing plate (6) is fixed on described installed part (20) and goes up and have at least one through hole for fixed sample.
3. rotary biochemical reaction case according to claim 2, is characterized in that, the plate face of described installing plate (6) and the axis of described rotating shaft (8) are 20 ° of-70 ° of angles.
4. rotary biochemical reaction case according to claim 2, is characterized in that,
Described installing plate (6) is fixed on described installed part (20) by angle adjusting mechanism, the angle that described angle adjusting mechanism can regulate the axis of the plate face of described installing plate (6) and rotating shaft (8) to be formed.
5. the rotary biochemical reaction case according to any one of claim 1-4, is characterized in that,
Described biochemical reaction cabinet also comprises temperature-controlling component, described temperature-controlling component comprises the ventilation unit for making described casing (1) inner air and outer air circulate be arranged on described casing (1) wall, and/or for the heating combined equipment that improves described casing (1) interior temperature and/or the refrigerating plant for reducing described casing (1) interior temperature.
6. rotary biochemical reaction case according to claim 5, it is characterized in that, also comprise Control Component and temperature sensor, described temperature sensor is for measuring the temperature in described casing (1), and the temperature value recorded is passed to described Control Component, described Control Component controls described ventilation unit or heating combined equipment or refrigerating plant according to temperature value and closes or start.
7. rotary biochemical reaction case according to claim 5, it is characterized in that, described refrigerating plant is arranged through the rear wall of casing (1), described refrigerating plant comprises the aerofoil fan (25) being positioned at casing (1) inner side, be arranged on the second radiator (27) on described aerofoil fan (25), be positioned at first radiator (21) in casing (1) outside, semiconductor refrigerating part (28) is provided with between described second radiator (27) and described first radiator (21), described aerofoil fan (25) makes described casing (1) interior air flow through described second radiator (27), heat in air passes to described semiconductor refrigerating part (28) through described second radiator (27), heat is dispersed into described casing (1) outward by described first radiator (21) by described semiconductor refrigerating part (28) again.
8. the rotary biochemical reaction case according to claim 5 or 6, it is characterized in that, described Control Component (3) is also connected with described rotating driving device (7) and/or described smooth radiation module, for described control rotating driving device (7) start/stop and control its rotating speed, and control On/Off and the intensity of illumination of described smooth radiation module.
9. the rotary biochemical reaction case according to any one of claim 1-8, it is characterized in that, described biochemical reaction cabinet comprises and is arranged in described casing (1) top inner wall and caves inward to form the space of installing described smooth radiation module, fluorescent lamp (22) and/or ultraviolet lamp (24) is provided with in described installing space, and described installing space opening part is provided with lampshade (26), so that described installing space is sealed.
10. the rotary biochemical reaction case according to any one of claim 1-9, is characterized in that, described casing (1) inwall has the specular layer (13) for reflection ray.
CN201510465501.1A 2015-07-31 2015-07-31 A kind of rotary biochemical reaction case Active CN105056859B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106244451A (en) * 2016-08-04 2016-12-21 江苏科技大学 A kind of magnetic force biochemistry mixing reactor
CN108693205A (en) * 2018-03-16 2018-10-23 钢研纳克检测技术股份有限公司 Detection device for multi metallic elements fast detector in a kind of portable soil of sample spin
CN110133167A (en) * 2019-05-28 2019-08-16 中世沃克(天津)科技发展股份有限公司 Photochemical derivatization device

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US20130221245A1 (en) * 2012-02-29 2013-08-29 Phoseon Technology, Inc. Air deflectors for heat management in a lighting module
CN204101434U (en) * 2014-08-25 2015-01-14 中科科隆光电仪器设备无锡有限公司 A kind of ozone box
CN104338501A (en) * 2014-11-04 2015-02-11 中国农业科学院棉花研究所 Adjustable photochemical reaction box
CN205109618U (en) * 2015-07-31 2016-03-30 张家港江苏科技大学产业技术研究院 Rotation type biochemical reactions case

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202700508U (en) * 2011-12-16 2013-01-30 北京航空航天大学 Artificial climate box capable of simulating various complex environments
US20130221245A1 (en) * 2012-02-29 2013-08-29 Phoseon Technology, Inc. Air deflectors for heat management in a lighting module
CN204101434U (en) * 2014-08-25 2015-01-14 中科科隆光电仪器设备无锡有限公司 A kind of ozone box
CN104338501A (en) * 2014-11-04 2015-02-11 中国农业科学院棉花研究所 Adjustable photochemical reaction box
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106244451A (en) * 2016-08-04 2016-12-21 江苏科技大学 A kind of magnetic force biochemistry mixing reactor
CN108693205A (en) * 2018-03-16 2018-10-23 钢研纳克检测技术股份有限公司 Detection device for multi metallic elements fast detector in a kind of portable soil of sample spin
CN110133167A (en) * 2019-05-28 2019-08-16 中世沃克(天津)科技发展股份有限公司 Photochemical derivatization device

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