CN105056132A - Traditional Chinese medicine composition for treating peyronie's disease - Google Patents
Traditional Chinese medicine composition for treating peyronie's disease Download PDFInfo
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- CN105056132A CN105056132A CN201510511918.7A CN201510511918A CN105056132A CN 105056132 A CN105056132 A CN 105056132A CN 201510511918 A CN201510511918 A CN 201510511918A CN 105056132 A CN105056132 A CN 105056132A
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Abstract
The invention belongs to the technical field of medicines and particularly relates to a traditional Chinese medicine composition for treating peyronie's disease. The traditional Chinese medicine composition for treating peyronie's disease is composed of the following crude drugs in parts by weight: 8-16 parts of curcuma zedoaria, 5-13 parts of alga, 5-13 parts of kelp, 16-24 parts of salvia miltiorrhiza, 8-16 parts of Chinese thorowax root, 5-13 parts of red peony root, 16-24 parts of cistanche deserticola, 16-24 parts of epimedium herb, 6-14 parts of cyperus rotundus, 16-24 parts of turmeric root-tuber, 8-16 parts of pericarpium citri reticulatae viride, 6-14 parts of beautiful sweetgum fruit, 16-24 parts of caulis spatholobi, 25-35 parts of fructus trichosanthis, 6-14 parts of cowherb seed, 11-19 parts of hawthorn and 6-14 parts of radix glycyrrhizae preparata. After the traditional Chinese medicine composition provided by the invention is used for treating 108 patients with peyronie's disease, the cure rate is 78.70% and the total effective ratio is 94.4% in three treatment courses.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine composition for the treatment of induration of penis.
Background technology
Induration of penis is also known as fibrous cavernositis of penis, nodositas spongiositis, spongy body fibrosis, the Peyronie's disease t cause of disease may be relevant with factors such as injury of penis, inflammation, diabetes, arteriosclerosis, gout, vitamin E deficiencies, be in the penis sea body between albuginea of cavernous body of penis and deep fascia every fibrosis lesion.Clinical manifestation is that the single or multiple scleroma sample of cavernous body of penis changes; pathological changes in early days under the microscope visible connective tissue layer blood vessel, have lymphocyte and plasmocyte infiltrating, then penis dorsal part spongy body every near formation be main speckle like collagen fiber; slow gradually after pathological changes primary growth is very fast; course of disease elder; localized calcific or ossified, do not cause ulcer, without cancerating tendency.But bending when often occurring erecing, pain, positive painful abdominal mass, scleroma appear at urethra side and also occur the symptoms such as dysuria, bring pain on the living conditions to patient.On clinical treatment, effective method is little, to take the way of excision habitually in the past.But the danger of operative treatment is comparatively large, and patient does not also take like a shot.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine composition and application thereof for the treatment of induration of penis.
The present invention is realized by following technical scheme:
Treat a Chinese medicine composition for induration of penis, be made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 8-16 part, Sargassum 5-13 part, Thallus Laminariae (Thallus Eckloniae) 5-13 part, Radix Salviae Miltiorrhizae 16-24 part, Radix Bupleuri 8-16 part, Radix Paeoniae Rubra 5-13 part, Herba Cistanches 16-24 part, Herba Epimedii 16-24 part, Rhizoma Cyperi 6-14 part, Radix Curcumae 16-24 part, Pericarpium Citri Reticulatae Viride 8-16 part, Fructus Liquidambaris 6-14 part, Caulis Spatholobi 16-24 part, Fructus Trichosanthis 25-35 part, Semen Vaccariae 6-14 part, Fructus Crataegi 11-19 part, Radix Glycyrrhizae Preparata 6-14 part.
Preferably, the Chinese medicine composition of above-mentioned treatment induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 10-14 part, Sargassum 7-11 part, Thallus Laminariae (Thallus Eckloniae) 7-11 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Bupleuri 10-14 part, Radix Paeoniae Rubra 7-11 part, Herba Cistanches 18-22 part, Herba Epimedii 18-22 part, Rhizoma Cyperi 8-12 part, Radix Curcumae 18-22 part, Pericarpium Citri Reticulatae Viride 10-14 part, Fructus Liquidambaris 8-12 part, Caulis Spatholobi 18-22 part, Fructus Trichosanthis 28-32 part, Semen Vaccariae 8-12 part, Fructus Crataegi 13-17 part, Radix Glycyrrhizae Preparata 8-12 part.
Preferred, the Chinese medicine composition of above-mentioned treatment induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 12 parts, Sargassum 9 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Bupleuri 12 parts, Radix Paeoniae Rubra 9 parts, Herba Cistanches 20 parts, Herba Epimedii 20 parts, Rhizoma Cyperi 10 parts, Radix Curcumae 20 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 10 parts, Caulis Spatholobi 20 parts, Fructus Trichosanthis 30 parts, Semen Vaccariae 10 parts, Fructus Crataegi 15 parts, Radix Glycyrrhizae Preparata 10 parts.
Or preferred, the Chinese medicine composition of above-mentioned treatment induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 10 parts, Sargassum 7 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Radix Salviae Miltiorrhizae 18 parts, Radix Bupleuri 10 parts, Radix Paeoniae Rubra 7 parts, Herba Cistanches 18 parts, Herba Epimedii 18 parts, Rhizoma Cyperi 8 parts, Radix Curcumae 18 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 8 parts, Caulis Spatholobi 18 parts, Fructus Trichosanthis 28 parts, Semen Vaccariae 8 parts, Fructus Crataegi 13 parts, Radix Glycyrrhizae Preparata 8 parts.
Or preferred, the Chinese medicine composition of above-mentioned treatment induration of penis, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 14 parts, Sargassum 11 parts, Thallus Laminariae (Thallus Eckloniae) 11 parts, Radix Salviae Miltiorrhizae 22 parts, Radix Bupleuri 14 parts, Radix Paeoniae Rubra 11 parts, Herba Cistanches 22 parts, Herba Epimedii 22 parts, Rhizoma Cyperi 12 parts, Radix Curcumae 22 parts, 14 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 12 parts, Caulis Spatholobi 22 parts, Fructus Trichosanthis 32 parts, Semen Vaccariae 12 parts, Fructus Crataegi 17 parts, Radix Glycyrrhizae Preparata 12 parts.
The application of Chinese medicine composition in preparation treatment penile induration disease drug of above-mentioned treatment induration of penis.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
Chinese medicine composition of the present invention has liver and kidney tonifying, depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, and effect of activating collaterals and eliminating stagnation, for induration of penis.
In the Chinese medicine composition for the treatment of induration of penis of the present invention, each crude drug is Chinese Pharmacopoeia 2010 editions 1 kinds recorded.
The induration of penis traditional Chinese medical science belongs to " carbuncle of yin nature " sick category.If depression of liver-QI, can not harmonizing the functional activities of vital QI, as " Plain Questions lifts pain opinion " say " all diseases being caused by disorder of QI also ", cause depression and stagnation of QI, normally can not follow row, eventually to stagnation of phlegm stasis by body fluid in push body.Vital essence in kidney is that gas is basic all over the body, if deficiency of kidney-QI, then the gas of body all declines, and must agitate unable, makes whole body QI-blood circulation not smooth, eventually to the stagnation of QI expectorant stasis of blood, sends out as carbuncle of yin nature.Meanwhile, the stagnation of QI, expectorant knot, also can reciprocal causation between stasis blocking, influences each other, final become the gesture of knot mutually, the state of an illness is increased the weight of gradually.Therefore, controlling of carbuncle of yin nature, based on Liver and kidney two warp, this, for controlling originally, must use the product of blood-activating and qi-promoting, expectorant blood stasis dispelling, to eliminate the mark of the stagnation of QI expectorant stasis of blood simultaneously.
The present invention treats in the Chinese medicine of induration of penis, Rhizoma Cyperi, Radix Curcumae, Radix Bupleuri, Pericarpium Citri Reticulatae Viride is soothing the liver promoting of the circulation of QI and removing the obstruction in the collaterals; Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Crataegi, Caulis Spatholobi, Rhizoma Curcumae blood circulation promoting and blood stasis dispelling: Semen Vaccariae can be invigorated blood circulation by pain, as Compendium of Material Medica speech " Semen Vaccariae can walk blood system, is the medicine that positive bright punching is appointed ... its property row and incessantly also "; Fructus Trichosanthis, Sargassum, Thallus Laminariae (Thallus Eckloniae), Fructus Liquidambaris eleminating phlegm and freeing channels eliminating stagnation; Herba Cistanches, Herba Epimedii the kidney invigorating gas; Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription.Full side's giving consideration to both the incidental and fundamental, makes that kidney qi must be mended, irritability must be dredged, mechanism of qi is happy, expectorant stagnation resolvation falls apart.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a Chinese medicine composition for induration of penis, each crude drug weight proportion is as follows:
Rhizoma Curcumae 12g, Sargassum 9g, Thallus Laminariae (Thallus Eckloniae) 9g, Radix Salviae Miltiorrhizae 20g, Radix Bupleuri 12g, Radix Paeoniae Rubra 9g, Herba Cistanches 20g, Herba Epimedii 20g, Rhizoma Cyperi 10g, Radix Curcumae 20g, Pericarpium Citri Reticulatae Viride 12g, Fructus Liquidambaris 10g, Caulis Spatholobi 20g, Fructus Trichosanthis 30g, Semen Vaccariae 10g, Fructus Crataegi 15g, Radix Glycyrrhizae Preparata 10g.
Embodiment 2
Treat a Chinese medicine composition for induration of penis, each crude drug weight proportion is as follows:
Rhizoma Curcumae 10g, Sargassum 7g, Thallus Laminariae (Thallus Eckloniae) 7g, Radix Salviae Miltiorrhizae 18g, Radix Bupleuri 10g, Radix Paeoniae Rubra 7g, Herba Cistanches 18g, Herba Epimedii 18g, Rhizoma Cyperi 8g, Radix Curcumae 18g, Pericarpium Citri Reticulatae Viride 10g, Fructus Liquidambaris 8g, Caulis Spatholobi 18g, Fructus Trichosanthis 28g, Semen Vaccariae 8g, Fructus Crataegi 13g, Radix Glycyrrhizae Preparata 8g.
Embodiment 3
Treat a Chinese medicine composition for induration of penis, each crude drug weight proportion is as follows:
Rhizoma Curcumae 14g, Sargassum 11g, Thallus Laminariae (Thallus Eckloniae) 11g, Radix Salviae Miltiorrhizae 22g, Radix Bupleuri 14g, Radix Paeoniae Rubra 11g, Herba Cistanches 22g, Herba Epimedii 22g, Rhizoma Cyperi 12g, Radix Curcumae 22g, Pericarpium Citri Reticulatae Viride 14g, Fructus Liquidambaris 12g, Caulis Spatholobi 22g, Fructus Trichosanthis 32g, Semen Vaccariae 12g, Fructus Crataegi 17g, Radix Glycyrrhizae Preparata 12g.
Embodiment 4
Treat a Chinese medicine composition for induration of penis, each crude drug weight proportion is as follows:
Rhizoma Curcumae 8g, Sargassum 5g, Thallus Laminariae (Thallus Eckloniae) 5g, Radix Salviae Miltiorrhizae 16g, Radix Bupleuri 8g, Radix Paeoniae Rubra 5g, Herba Cistanches 16g, Herba Epimedii 16g, Rhizoma Cyperi 6g, Radix Curcumae 16g, Pericarpium Citri Reticulatae Viride 8g, Fructus Liquidambaris 6g, Caulis Spatholobi 16g, Fructus Trichosanthis 25g, Semen Vaccariae 6g, Fructus Crataegi 11g, Radix Glycyrrhizae Preparata 6g.
Embodiment 5
Treat a Chinese medicine composition for induration of penis, each crude drug weight proportion is as follows:
Rhizoma Curcumae 16g, Sargassum 13g, Thallus Laminariae (Thallus Eckloniae) 13g, Radix Salviae Miltiorrhizae 24g, Radix Bupleuri 16g, Radix Paeoniae Rubra 13g, Herba Cistanches 24g, Herba Epimedii 24g, Rhizoma Cyperi 14g, Radix Curcumae 24g, Pericarpium Citri Reticulatae Viride 16g, Fructus Liquidambaris 14g, Caulis Spatholobi 24g, Fructus Trichosanthis 35g, Semen Vaccariae 14g, Fructus Crataegi 19g, Radix Glycyrrhizae Preparata 14g.
Carried out clinical pharrnacokinetics test to the Chinese medicine composition of embodiments of the invention l, Details as Follows:
1. data and method
1. physical data
Patient's totally 108 examples of induration of penis.Age 26-58 year, 42 years old mean age.Wherein there is obvious trauma history 26 example.Suffered from 22 examples of spongiositis, agnogenic 60 examples.36 examples of tuberosity diameter in 1cm, diameter is in 48 examples of 1-2cm, and 16 examples of diameter in 2-3cm, diameter is in more than 3cm person 8 example.Pain when wherein having 62 examples to erect, 24 examples of ache influence sexual intercourse, positive painful abdominal mass 12 example, 4 examples that can not have sexual intercourse completely, scleroma appears at urethra side urethra, occurs dysuric 2 examples.。
2. Therapeutic Method
Give the Chinese medicine composition of the embodiment of the present invention 1, prescription: Rhizoma Curcumae 12g, Sargassum 9g, Thallus Laminariae (Thallus Eckloniae) 9g, Radix Salviae Miltiorrhizae 20g, Radix Bupleuri 12g, Radix Paeoniae Rubra 9g, Herba Cistanches 20g, Herba Epimedii 20g, Rhizoma Cyperi 10g, Radix Curcumae 20g, Pericarpium Citri Reticulatae Viride 12g, Fructus Liquidambaris 10g, Caulis Spatholobi 20g, Fructus Trichosanthis 30g, Semen Vaccariae 10g, Fructus Crataegi 15g, Radix Glycyrrhizae Preparata 10g.Be decocted in water for oral dose, 1 day 1 dose.It within 10 days, was 1 course for the treatment of.All avoid during all patient treatments and take pungent stimulation food, spirits and inebriant.
3. therapeutic outcome
After all treatments of 3.1 criterion of therapeutical effect, penile induration disappears, and the clinical symptoms such as phallocampsis, pain eliminator is clinical cure; After treatment, penile induration reduces, and the clinical symptoms such as phallocampsis, pain improver is effectively clinical; After treatment, penile induration is unchanged or increase further, and clinical symptoms is without improvement or to add severe one be invalid.
3.2
In 108 routine patients, 3 the clinical 85 example recoveries from illness course for the treatment of, 17 examples take a turn for the better, and 6 examples are invalid.3 course cure rates 78.70%, total effective rate 94.40%.
The routine patient of 3.3 untoward reaction 108 is showed no untoward reaction.
Claims (6)
1. treat a Chinese medicine composition for induration of penis, be made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 8-16 part, Sargassum 5-13 part, Thallus Laminariae (Thallus Eckloniae) 5-13 part, Radix Salviae Miltiorrhizae 16-24 part, Radix Bupleuri 8-16 part, Radix Paeoniae Rubra 5-13 part, Herba Cistanches 16-24 part, Herba Epimedii 16-24 part, Rhizoma Cyperi 6-14 part, Radix Curcumae 16-24 part, Pericarpium Citri Reticulatae Viride 8-16 part, Fructus Liquidambaris 6-14 part, Caulis Spatholobi 16-24 part, Fructus Trichosanthis 25-35 part, Semen Vaccariae 6-14 part, Fructus Crataegi 11-19 part, Radix Glycyrrhizae Preparata 6-14 part.
2. the Chinese medicine composition for the treatment of induration of penis according to claim 1, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 10-14 part, Sargassum 7-11 part, Thallus Laminariae (Thallus Eckloniae) 7-11 part, Radix Salviae Miltiorrhizae 18-22 part, Radix Bupleuri 10-14 part, Radix Paeoniae Rubra 7-11 part, Herba Cistanches 18-22 part, Herba Epimedii 18-22 part, Rhizoma Cyperi 8-12 part, Radix Curcumae 18-22 part, Pericarpium Citri Reticulatae Viride 10-14 part, Fructus Liquidambaris 8-12 part, Caulis Spatholobi 18-22 part, Fructus Trichosanthis 28-32 part, Semen Vaccariae 8-12 part, Fructus Crataegi 13-17 part, Radix Glycyrrhizae Preparata 8-12 part.
3. the Chinese medicine composition for the treatment of induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 12 parts, Sargassum 9 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Bupleuri 12 parts, Radix Paeoniae Rubra 9 parts, Herba Cistanches 20 parts, Herba Epimedii 20 parts, Rhizoma Cyperi 10 parts, Radix Curcumae 20 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 10 parts, Caulis Spatholobi 20 parts, Fructus Trichosanthis 30 parts, Semen Vaccariae 10 parts, Fructus Crataegi 15 parts, Radix Glycyrrhizae Preparata 10 parts.
4. the Chinese medicine composition for the treatment of induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 10 parts, Sargassum 7 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Radix Salviae Miltiorrhizae 18 parts, Radix Bupleuri 10 parts, Radix Paeoniae Rubra 7 parts, Herba Cistanches 18 parts, Herba Epimedii 18 parts, Rhizoma Cyperi 8 parts, Radix Curcumae 18 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 8 parts, Caulis Spatholobi 18 parts, Fructus Trichosanthis 28 parts, Semen Vaccariae 8 parts, Fructus Crataegi 13 parts, Radix Glycyrrhizae Preparata 8 parts.
5. the Chinese medicine composition for the treatment of induration of penis according to claim 2, is characterized in that, is made up of the traditional Chinese medicinal composition raw materials of following weight portion:
Rhizoma Curcumae 14 parts, Sargassum 11 parts, Thallus Laminariae (Thallus Eckloniae) 11 parts, Radix Salviae Miltiorrhizae 22 parts, Radix Bupleuri 14 parts, Radix Paeoniae Rubra 11 parts, Herba Cistanches 22 parts, Herba Epimedii 22 parts, Rhizoma Cyperi 12 parts, Radix Curcumae 22 parts, 14 parts, Pericarpium Citri Reticulatae Viride, Fructus Liquidambaris 12 parts, Caulis Spatholobi 22 parts, Fructus Trichosanthis 32 parts, Semen Vaccariae 12 parts, Fructus Crataegi 17 parts, Radix Glycyrrhizae Preparata 12 parts.
6. the application of Chinese medicine composition in preparation treatment penile induration disease drug of the treatment induration of penis described in the arbitrary claim of claim 1-5.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106390017A (en) * | 2016-09-30 | 2017-02-15 | 毛华养 | Multi-TCM (Traditional Chinese Medicine) composition for effectively treating macrodactyly |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069440A (en) * | 2014-07-15 | 2014-10-01 | 王福刚 | Traditional Chinese medicine for treating penis hardening disease |
| CN104116904A (en) * | 2014-08-09 | 2014-10-29 | 孟红琳 | Traditional Chinese medicine for treating penile induration |
| CN104288695A (en) * | 2014-10-23 | 2015-01-21 | 滨州医学院 | Medicament for treating peyronie's disease and preparation method of medicament |
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- 2015-08-20 CN CN201510511918.7A patent/CN105056132A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069440A (en) * | 2014-07-15 | 2014-10-01 | 王福刚 | Traditional Chinese medicine for treating penis hardening disease |
| CN104116904A (en) * | 2014-08-09 | 2014-10-29 | 孟红琳 | Traditional Chinese medicine for treating penile induration |
| CN104288695A (en) * | 2014-10-23 | 2015-01-21 | 滨州医学院 | Medicament for treating peyronie's disease and preparation method of medicament |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106390017A (en) * | 2016-09-30 | 2017-02-15 | 毛华养 | Multi-TCM (Traditional Chinese Medicine) composition for effectively treating macrodactyly |
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Application publication date: 20151118 |