CN105055795A

CN105055795A - Drug for treating toxic heat type mumps

Info

Publication number: CN105055795A
Application number: CN201510505609.9A
Authority: CN
Inventors: 邢春红; 刘宁
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-08-11
Filing date: 2015-08-11
Publication date: 2015-11-18

Abstract

The invention relates to the field of pharmaceutical formulation, in particular to a drug for treating toxic heat type mumps. The drug is characterized by being prepared from the following raw medicinal materials in parts by weight: 5-9 parts of radix semiaquilegiae, 4-7 parts of honeysuckle stem, 4-8 parts of peucedanum, 4-7 parts of cyrtomium fortunei, 4-8 parts of natural indigo, 5-8 parts of herba schizonepetae, 6-9 parts of selaginella doederleinii hieron, 6-9 parts of uncaria rhynchophylla, 7-9 parts of dayflower, 6-9 parts of gentian, 2-5 parts of akebiaquinata, 6-9 parts of terminalia chebula, 2-5 parts of manyleaf paris rhizome, 4-6 parts of rubus idaeus, 2-4 parts of spreading hedyotis herb, 4-6 parts of asarum sieboldii, 2-4 parts of scutellaria baicalensis and 7-9 parts of radix aconiti kusnezoffii. The preparation method includes the following steps: soaking the raw medicinal materials in water, decocting and then removing the slag to obtain the filtrate.

Description

The parotitic medicine for the treatment of heat-toxin type

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically one is used for the treatment of the parotitic medicine of heat-toxin type.

Background technology

As everyone knows, heat-toxin type parotitis is because experiencing the evil poison of pathogenic wind-warm, stops up that resistance shaoyang channel arteries and veins causes, and to generate heat, under ear, cheek overflows swollen pain is the epidemic disease disease of main manifestations, and modern medicine is called mumps.Its main manifestations is heating, enlargement under the ear-lobe of one or both sides, and the parotid gland of enlargement is often in hemispherical, blur margin centered by ear-lobe, surface heat has angle pain, and when dehiscing or chew, pain is felt in local, has minority complication to be meningitis, orchitis and oophoritis.Study carefully its pathogenic factor, Chinese medicine thinks that the evil poison of pathogenic wind-warm is from muzzle invasion, inside attacks few sun, fights mutually with QI and blood, cheek under the ear that stagnates, and becomes this sick eventually.

Summary of the invention

Object of the present invention is exactly to overcome existing technical deficiency, provides a kind of evident in efficacy, with low cost, parotitic medicine for the treatment of heat-toxin type of having no side effect.

The technical scheme that the present invention solves the problems of the technologies described above employing is: one treats the parotitic medicine of heat-toxin type, it is characterized in that being made up of the crude drug of following weight portion: Radix Semiaquilegiae 5 ~ 9, Caulis Lonicerae 4 ~ 7, Radix Peucedani 4 ~ 8, Rhizoma Osmundae 4 ~ 7, Indigo Naturalis 4 ~ 8, Herba Schizonepetae 5 ~ 8, Herba Selaginellae Doederleinii 6 ~ 9, Ramulus Uncariae Cum Uncis 6 ~ 9, Herba Commelinae 7 ~ 9, Radix Gentianae 6 ~ 9, Caulis Akebiae 2 ~ 5, Fructus Chebulae 6 ~ 9, Rhizoma Paridis 2 ~ 5, Fructus Rubi 4 ~ 6, Herba Hedyotidis Diffusae 2 ~ 4, Herba Asari 4 ~ 6, Radix Scutellariae 2 ~ 4, Radix Aconiti Kusnezoffii 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, filtrate of removing slag after decocting to obtain.

The invention has the beneficial effects as follows, evident in efficacy, with low cost, have no side effect.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Radix Semiaquilegiae, Caulis Lonicerae, Radix Peucedani, Rhizoma Osmundae, Indigo Naturalis, Herba Schizonepetae, Herba Selaginellae Doederleinii, Ramulus Uncariae Cum Uncis, Herba Commelinae, Radix Gentianae, Caulis Akebiae, Fructus Chebulae, Rhizoma Paridis, Fructus Rubi, Herba Hedyotidis Diffusae, Herba Asari, Radix Scutellariae, Radix Aconiti Kusnezoffii is adopted to be that raw material is prepared from.The every pair of its component (weight portion) is Radix Semiaquilegiae 7, Caulis Lonicerae 6, Radix Peucedani 6, Rhizoma Osmundae 5, Indigo Naturalis 6, Herba Schizonepetae 6, Herba Selaginellae Doederleinii 7, Ramulus Uncariae Cum Uncis 7, Herba Commelinae 8, Radix Gentianae 7, Caulis Akebiae 4, Fructus Chebulae 8, Rhizoma Paridis 3, Fructus Rubi 5, Herba Hedyotidis Diffusae 3, Herba Asari 5, Radix Scutellariae 3, Radix Aconiti Kusnezoffii 8.Get above-mentioned 18 taste raw materials, gross weight is 176 grams, add water 800 ~ 900 milliliters and at room temperature soak 5 ~ 6 hours, slow fire decocted to 60 ~ 80 minutes, filtrate about 150 milliliters of removing slag to obtain, and medicinal residues add water 200 ~ 300ml again, decoct 20 ~ 30 minutes, to remove slag to obtain filtrate 50 ~ 70 milliliters, altogether the medicine juice of about 200 ~ 220 milliliters, i.e. obtained decoction of the present invention.Load in sterile glass vials, seal bottle cap is for subsequent use, and every day 1 dose point 2 times is oral, sooner or later respectively once, and each (medicine) being taken before meal 100 ~ 110 milliliters.

Radix Semiaquilegiae of the present invention has heat-clearing and toxic substances removing, effect of dispersing swelling and dissipating binds; Caulis Lonicerae has heat-clearing and toxic substances removing, the curative effect of dispelling wind dredging collateral.Can be used for epidemic febrile disease heating, sore and toxic, toxic-heat and blood stasis, beriberoid pyretic arthralgia; Radix Peucedani falls apart wind heat clearing away, lowering the adverse-rising QI to resolve phlegm.Sticky for affection due to external wind and heat, lung-heat phlegm stagnancy, cough with asthma abundant expectoration, expectorant Huang; Rhizoma Osmundae is used for anemopyretic cold, hot skin eruption, spits blood, hemoptysis; The effects such as Indigo Naturalis has heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, pathogenic fire purging arresting convulsion; Herba Schizonepetae be used for flu, headache, measles, rubella, skin infection from the beginning of; Herba Selaginellae Doederleinii has heat-clearing and toxic substances removing, anticancer, effect of hemostasis.Be usually used in laryngopharynx swelling and pain, conjunctival congestion and swelling pain, cough due to lung-heat; Ramulus Uncariae Cum Uncis has the function of calmness, blood pressure lowering, heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion, dizzy for having a headache, and dysphoric cold, infantile convulsion are twitched, pre-eclampsia, the diseases such as hypertension; The heat clearing away of Herba Commelinae energy, removing toxic substances, diuresis.For the good medicine of swelling diuretic, heat-clearing and toxic substances removing; Radix Gentianae controls sudden onset of precordial pain, and worm is made a psychological attack bitterly, limbs pain; Caulis Akebiae is used for stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, and amenorrhea breast is few, damp and hot arthralgia pain; Fructus Chebulae has relieving diarrhea with astringents, astringing lung-QI and relieving cough, effect of pathogenic fire reducing sore-throat relieving; Rhizoma Paridis heat-clearing and toxic substances removing, antiasthmatic-antitussive, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, detumescence hemostasis; Fructus Rubi has supplementing the kidney to control the nocturnal reducing urination, effect of nourishing the liver to improve visual acuity; Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness; Herba Asari induces sweat cold expelling, and wind-expelling pain-stopping is sensible, warming the lung to resolve fluid-retention; Radix Scutellariae has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat; Radix Aconiti Kusnezoffii has expelling wind and removing dampness, dispelling cold by warming the meridian, effect of reducing swelling and alleviating pain.

The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize.Its processing technique is identical with embodiment 1.

The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:

1, physical data

In 53 routine patients, in age 10-23 year, the course of disease is many at 2-5 days, 16 years old mean age.

2, diagnostic criteria

" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:

Can have heating during 2.1 onset, 1 ~ 2 day visible unrestrained swollen centered by ear-lobe afterwards, and blur margin, color of the leather is not red, and having of pressure is keenly felt and elastic sensation, usually first sees side, then sees opposite side.

2.2 orifice of parotid duct or red and swollen as seen.Swelling of parotid gland about continues to start to disappear for 4 ~ 5 days, the whole course of disease about 1 ~ 2 week.

Parotitis contact history is had before 2.3 diseases.

2.4 blood leukocytes sums can be normal, or slightly increase and reduce, and lymphocyte can increase relatively.

2.5 incidence of meningitis or encephalitis persons, cerebrospinal pressure increases, and cell number increases, and based on lymphocyte, chloride, sugar are normal, and albumen slightly increases.

2.6 urine and blood amylase can increase.

Heat-toxin type parotitis symptom: fever and headache, unconsciousness and delirium, under bilateral ear, cheek swells, and dehisces unfavorable, and xerostomia is for drink, and vomiting right after eating, urine is urinated red, red tongue with yellowish and greasy fur, forceful pulse and counting.

3, Therapeutic Method

Take embodiment one decoction, every day 1 dose point 2 times is oral, and sooner or later each once each (medicine) being taken before meal 100 ~ 110 milliliters 3 days was 1 course for the treatment of, treated 3 courses for the treatment of altogether.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Cure: body temperature is normal, and mumps disappears completely, without complication.

Take a turn for the better: mumps and all diseases alleviate.

Do not heal: mumps has no improvement, or occur deteriorated case.

4.2 results: in 53 routine patients, cure 41 examples (77.4%), 12 examples that take a turn for the better (22.6%), and do not heal 0 example, and total effective rate is 100%.

5, model case

Grandson, female, 13 years old.High heat 2 days, body temperature 38.5 DEG C-39.5 DEG C, headache, swallows red, and orifice of parotid duct is red and swollen, overflows swollen 2 days under bilateral ear-lobe, and pain of dehiscing is indigestion and loss of appetite, constipation, and yellow urine, cardiopulmonary check without exception, and red tongue, yellow fur, stringy pulse is really done one's bit inside.Be diagnosed as heat-toxin type parotitis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, recovery from illness.

Often certain, male, 12 years old.Body temperature 39.2 DEG C, bilateral parotid fills the air enlargement, hard, tenderness, tenderness, ripple disable, and pharyngitis chews dysphagia, companion's flushed face, thirsty agitation, anorexia, lethargy, yellowish urine constipation, red tongue, yellow and thin fur, forceful pulse and counting.Be diagnosed as heat-toxin type parotitis.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, recovery from illness.

Hu, female, 17 years old, swollen hard pain under the ear of left side, mild pain under the ear of right side, not firmly, and fever, slight aversion to cold, tired, vomiting, dysphagia, liquid of only taking food.Inspection is shown in that in cheek, orifice of parotid duct is red and swollen, thirsty constipation, red tongue, yellow fur, rapid pulse.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, symptom is clearly better, and continues to take 1 course for the treatment of, recovery from illness.

Claims

1. the parotitic medicine for the treatment of heat-toxin type, it is characterized in that being made up of the crude drug of following weight portion: Radix Semiaquilegiae 5 ~ 9, Caulis Lonicerae 4 ~ 7, Radix Peucedani 4 ~ 8, Rhizoma Osmundae 4 ~ 7, Indigo Naturalis 4 ~ 8, Herba Schizonepetae 5 ~ 8, Herba Selaginellae Doederleinii 6 ~ 9, Ramulus Uncariae Cum Uncis 6 ~ 9, Herba Commelinae 7 ~ 9, Radix Gentianae 6 ~ 9, Caulis Akebiae 2 ~ 5, Fructus Chebulae 6 ~ 9, Rhizoma Paridis 2 ~ 5, Fructus Rubi 4 ~ 6, Herba Hedyotidis Diffusae 2 ~ 4, Herba Asari 4 ~ 6, Radix Scutellariae 2 ~ 4, Radix Aconiti Kusnezoffii 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, filtrate of removing slag after decocting to obtain.