CN105055047A - Vascular stent for treating cerebral artery bifurcation aneurysms and its application - Google Patents

Vascular stent for treating cerebral artery bifurcation aneurysms and its application Download PDF

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Publication number
CN105055047A
CN105055047A CN201510436364.9A CN201510436364A CN105055047A CN 105055047 A CN105055047 A CN 105055047A CN 201510436364 A CN201510436364 A CN 201510436364A CN 105055047 A CN105055047 A CN 105055047A
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rack body
far
closing structure
described rack
aneurysm
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CN201510436364.9A
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Chinese (zh)
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高不郎
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Individual
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Individual
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Abstract

The invention relates to a vascular stent for treating cerebral artery bifurcation aneurysms, comprising a stent body of a mesh structure. A proximal end of the stent body is open, and a distal end thereof is closed; the distal end has a certain inclination. The stent body is tubular, with the distal end expanding out in a flared form. The invention further provides application of the vascular stent. The vascular stent is convenient to use to treat bifurcation aneurysms different in angle and form, allows the aneurysms to be better closed and ensures simplified therapeutic operations and improved therapy safety.

Description

For the aneurysmal intravascular stent of cerebral arteries crotch and application thereof
Technical field
The invention belongs to medical instruments field, be specifically related to the treatment aneurysmal intravascular stent of cerebral arteries crotch and application thereof.
Background technology
Aneurysm is a kind of permanent expansion disease occurred due to ductus arteriosus wall local weak.Cerebral aneurysm belongs to peripheral arterial aneurysm, refers to the tumor sample projection that the expansion of cerebral arteries tube wall limitation produces, the aneurysm tumor wall of projection thinning gradually and final Rupture haemorrhag under the continuous impact of blood flow.Ruptured intracranial aneurysm morbidity urgency, severe symptoms, without obvious tendency, there is very high mortality rate and disability rate.The treatment of a cerebral aneurysm mainly point surgical clamp is closed and is treated with endovascular intervention.But surgical clamp is closed, and wound is large, complication is many, operation and recovery time all very long, not by the welcome of doctor and patient.Along with the progress of the intravascular Interventional Treatment technology of invasive, increasing cerebral aneurysms accepts intravascular Interventional Treatment technology, and endovascular intervention technology also becomes the dominant technology of cerebral aneurysm treatment gradually.
The Endovascular Embolization of cerebral aneurysm, mainly use detachable coil is implanted in aneurysm by microtubular and is carried out thromboembolism, makes form thrombosis in aneurysm cavity and close and reach dissection healing.For being positioned at the wide neck aneurysm at aortic bifurcation place, simple turn is not easy thromboembolism, often needs support to assist thromboembolism (as Fig. 1); At this moment, need to insert respectively in two Main Branches of two support intravasations, just can carry out Coil embolization treatment.Have three steps: the first step, insert first support (label 7 in Fig. 1); Second step, intersects and inserts second support (label 8 in Fig. 1); 3rd step, puts into aneurysm by microtubular by two supports that intersection is inserted and carries out turn (label 9 of Fig. 1) thromboembolism.Such step operation is more loaded down with trivial details, and support is also wide to the coverage of blood vessel, may cause unnecessary branch vessel tube wall hypertrophy, narrow even obturation; When inserting operation, complicated operation also may cause thrombosis, causes unnecessary embolic complications.In addition, if only implant a support, aneurysm oral area can not be closed well again, carry out safe treatment.This support and operational approach are both dangerous, also inconvenient above, a kind ofly use simple, easy to operate support to be used for the treatment of cerebral arteries crotch aneurysm in the urgent need to developing.
Summary of the invention
Technical problem to be solved by this invention is to provide one and is used for the treatment of the aneurysmal intravascular stent of cerebral arteries crotch, is convenient to place and treatment crotch aneurysm, improves the safety for the treatment of, and simplifies therapeutic progresses.
The present invention solves the problem and adopts following technical scheme: a kind of for the aneurysmal intravascular stent of cerebral arteries crotch, comprise: rack body, described rack body is network structure, and the near-end of described rack body is open, and far-end is netted closing structure; Described rack body is circular tube shaped, and far-end expands outwardly in enlarging shape.
Preferably, each grid circumscribed circle diameter of the netted closing structure of described rack far end is 1 millimeter-3 millimeters, passes for seal wire, and namely the mesh circumscribed circle diameter of netted closing structure is 1-3mm.
Preferably, the netted closing structure of described rack body far-end is formed slopely different angles, and namely the axis of the rack body of netted closing structure place plane and circular tube shaped acutangulates, to coordinate the aneurysm of different shape and angle.
Preferably, the near-end afterbody of described rack body arranges more than one metal marker thing.
Preferably, the network structure of described rack body is hollow out cutting or filamentary material braiding.
Preferably, intravascular stent of the present invention is eject or the swollen formula of ball.
Preferably, the netted enclosed construction of described rack body far-end arranges more than one metal marker thing.
Preferably, the netted closing structure outer of described rack body far-end arranges endless metal silk, improves the stability of netted closing structure.
The rack body of intravascular stent of the present invention is composites of any one or any two compositions of titanium silk, tungsten filament, nitinol alloy wire, tantalum wire, stainless steel silk, billon silk.Or select absorbable material or medical material, and as: Merlon, polyanhydride copolymer, gel or magnesium alloy.
The present invention provides the application of this support simultaneously, and it is for cerebral arteries crotch aneurysm.
During support release of the present invention, by the grid of micro-wire by netted closing structure, be placed in the arterial branch of crotch, support delivered to the aneurysm mouth at aortic bifurcation place along seal wire, releasing bracket.
Intravascular stent of the present invention and guiding wire, carry microtubular, conveying lever, guiding catheter with the use of, be and well known to a person skilled in the art prior art.
Stent body of the present invention has contractility, under release conditions, profile is netted cylindrical shape, suitable with the cerebral artery vessel inwall at aneurysm place, shrinking under feed status is fixed in microtubular, and under the guiding of guiding wire, the aneurysm place of aortic bifurcation is delivered to through guiding catheter, release is used for the treatment of aneurysm.
The netted closing structure of described far-end has the shutoff face of shutoff aneurysm blood vessel wall opening in the released state, and in order to improve plugging effect, shutoff mask has the angle of inclination of mating with blood vessel.
Good effect of the present invention is:
(1) rack body and arteries inwall suitable, far-end to expand outwardly in enlarging shape and can increase adhesive force to blood vessel at crotch, prevent support from coming off, and the aneurysmal oral area of shutoff well.
(2) rack far end is that netted closing structure can directly be closed in aneurysm oral area, and this is better than intersecting implantation two stent in the treatment furcation cerebral aneurysms, Coil embolization is treated easier.
(3) the netted enclosed construction of rack far end is formed slopely certain angle, matches with the angle of inclination of blood vessel, may be used for the crotch aneurysm for the treatment of different angles, and can close aneurysm cavity better.
(4) near-end is open, makes blood can enter far-end branch blood vessel normal through support.
(5) the metal marker thing of near-end and far-end closing structure is convenient to placement site, location, when releasing bracket, the radiopaque metal marker thing of rack far end is allowed to be positioned at aortic bifurcation place aneurysm oral area, fixed support conveying lever, withdraw microtubular gradually, support just can be released to appropriate location.Now connect power supply, use electrolysis is de-to be freed conveying lever from support and withdraws from conveying lever.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of prior art treatment aortic bifurcation place aneurysm method;
Fig. 2 is the structural representation of the embodiment of the present invention 1;
Fig. 3 is the schematic diagram that embodiment 1 discharges rear enclosed aneurysm oral area;
Fig. 4 is the structural representation of embodiment 2;
Fig. 5 is the schematic diagram that embodiment 2 discharges rear enclosed aneurysm oral area;
Fig. 6 is the structural representation of embodiment 3;
Fig. 7 is the schematic diagram that embodiment 3 discharges rear enclosed aneurysm oral area;
Fig. 8 is the schematic diagram of the present invention's release and Coil embolization process when using;
In accompanying drawing, 1 rack body, 2 netted closing structures, 3 microtubulars, 4 conveying levers, 5 metal marker things, 6 endless metal silks, 7 first supports, 8 second supports, 9 turns, 10 aneurysms, 11 micro-wires.
Detailed description of the invention
For enabling above-mentioned purpose of the present invention, feature and advantage become apparent more, below in conjunction with the drawings and specific embodiments in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
embodiment 1
As shown in Figure 2, embodiment 1 comprises rack body 1, and described rack body 1 is network structure, and the near-end of described rack body 1 is open, and far-end is netted closing structure 2; Described rack body 1 is circular tube shaped, and far-end expands outwardly in enlarging shape.
Each grid circumscribed circle diameter of the netted closing structure 2 of described rack body 1 far-end is 1-3mm.
Netted closing structure 2 outer of described rack body 1 far-end arranges endless metal silk 6, strengthens the stability of netted closing structure 2.
Described rack body 1 near-end afterbody arranges two metal marker things 5.
Embodiment 1 support is eject or the swollen formula of ball.
The netted closing structure 2 of described rack body 1 far-end arranges two metal marker things 5.
Rack body 1 of the present invention forms for nitinol alloy wire weaves.
Top of the present invention intravascular stent and guiding wire, microtubular, conveying lever and guiding catheter with the use of, be and well known to a person skilled in the art prior art.
The rack body 1 of intravascular stent of the present invention has contractility, under release conditions, profile is netted cylindrical shape, suitable with the cerebral artery vessel inwall at aneurysm 10 place, shrink under feed status and be fixed in microtubular, and under the guiding of micro-wire, be delivered to the aneurysm place of aortic bifurcation.
As shown in Figure 3, the netted closing structure 2 of described rack body 1 far-end has the shutoff face of shutoff aneurysm 10 blood vessel wall opening in the released state.
embodiment 2
As shown in Figure 4, embodiment 2 difference from Example 1 is that the netted closing structure 2 place plane of rack far end becomes 75.58 ° of acute angles with the axis of rack body 1.
As shown in Figure 5, the netted enclosed construction of far-end 2 of rack body 1 is skewed when support is in vertical position, matches with the angle of inclination of blood vessel, can close aneurysm mouth better.When Liu Kouchu branch tremulous pulse angle is 75.58 ° (90 °-14.42 °), the angle of the axis of embodiment 2 far-end netted closing structure 2 place plane and rack body is 75.88 ° (90 °-14.12 °), improves blind end to the laminating closure of tumor mouth.
embodiment 3
As shown in Figure 6, embodiment 3 difference from Example 1 is that netted closing structure 2 place plane becomes 67.22 ° of acute angles with the axis of rack body 1.
As shown in Figure 7, netted closing structure 2 is skewed when support is in vertical position, matches with the angle of inclination of blood vessel, can close aneurysm mouth better.When Liu Kouchu branch tremulous pulse angle is 67.22 ° (90 °-22.78 °), the angle of the axis of embodiment 3 far-end netted closing structure 2 place plane and rack body is 66.48 ° (90 °-23.52 °), improves blind end to the laminating closure of tumor mouth.
support method for releasing
As shown in Figure 8, when intravascular stent release of the present invention, first micro-wire 11 is sent into a bifurcated artery at aortic bifurcation place, then along micro-wire 11, the microtubular 3 comprising support is delivered to aortic bifurcation place, withdraw from micro-wire 11.Then rack far end pushed forward is placed in crotch aneurysm mouth place, is judged that whether position is correct according to the metal marker thing 5 of rack far end; Fix conveying lever 4 again, slowly withdraw microtubular 3, support is just released to 10 mouthfuls, aneurysm place gradually, and the netted enclosed construction 2 of rack far end just withstands on aneurysm mouth.According to the position of the metal marker thing 5 of rack far end, support not completely release time slightly regulate the position of support, releasing bracket completely again after position is excellent, and support is freed in energising, withdraws from conveying lever 4 and microtubular 3.Subsequently, import micro-wire 11 to branch vessel, turn is delivered in aneurysm cavity along micro-wire and carries out Coil embolization therapeutic process.Micro-wire and microtubular are stretched into the technology of carrying out Coil embolization in aneurysm cavity after simplifying current implantation two supports by such operation again.Meanwhile, the netted enclosed construction of cantilever tip forms different angles of inclination, matches with the blood vessel angle of crotch, can the oral area of shutoff aneurysm better.Rack body far-end of the present invention expands outwardly in enlarging shape, adds the power of rack body in aortic bifurcation place attachment blood vessel wall, makes support difficult drop-off.

Claims (9)

1. for the aneurysmal intravascular stent of cerebral arteries crotch, it is characterized in that, comprising: rack body (1), described rack body (1) is network structure, and the near-end of described rack body (1) is open, and far-end arranges netted closing structure (2); Described rack body (1) is circular tube shaped, and far-end expands outwardly in enlarging shape.
2. intravascular stent according to claim 1, is characterized in that, each grid circumscribed circle diameter of the netted closing structure (2) of described rack body (1) far-end is 1-3mm.
3. top according to claim 1 overlay film frame, is characterized in that, the axis of described netted closing structure (2) place plane and rack body (1) acutangulates.
4. top according to claim 1 overlay film frame, is characterized in that, described rack body (1) near-end afterbody arranges more than one metal marker thing (5).
5. top according to claim 1 overlay film frame, is characterized in that, the network structure of described rack body (1) is hollow out cutting or filamentary material braiding.
6. top according to claim 1 overlay film frame, is characterized in that, it is eject or the swollen formula of ball.
7. top according to claim 1 overlay film frame, is characterized in that, the netted closing structure (2) of described rack body (1) far-end arranges more than one metal marker thing (6).
8. the application of the top overlay film frame described in any one of claim 1-7, is characterized in that, for cerebral arteries crotch aneurysm.
9. application according to claim 8, is characterized in that, by the grid of micro-wire by netted closing structure during support release, is placed in the arterial branch of crotch, support is directed into crotch and is discharged.
CN201510436364.9A 2015-07-23 2015-07-23 Vascular stent for treating cerebral artery bifurcation aneurysms and its application Pending CN105055047A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901794A (en) * 2017-03-03 2017-06-30 高不郎 Aneurysm clip for treating the arterial side wall with vessel branch and terminal aneurysm

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050096728A1 (en) * 2003-10-29 2005-05-05 Marc Ramer Neck covering device for an aneurysm
US20110245862A1 (en) * 2006-08-17 2011-10-06 Tsunami Innovations Llc Isolation devices for the treatment of aneurysms
CN102762156A (en) * 2009-09-04 2012-10-31 帕尔萨维斯库勒公司 Systems and methods for enclosing an anatomical opening
CN102764170A (en) * 2012-07-18 2012-11-07 吕文峰 Intravascular stent with complex functions
CN103237526A (en) * 2010-12-06 2013-08-07 科维蒂恩有限合伙公司 Vascular remodeling device
CN104736071A (en) * 2012-08-22 2015-06-24 菲诺克斯有限公司 Implant
CN204814292U (en) * 2015-07-23 2015-12-02 高不郎 A top tectorial membrane support for cerebral artery crotch aneurysm

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050096728A1 (en) * 2003-10-29 2005-05-05 Marc Ramer Neck covering device for an aneurysm
US20110245862A1 (en) * 2006-08-17 2011-10-06 Tsunami Innovations Llc Isolation devices for the treatment of aneurysms
CN102762156A (en) * 2009-09-04 2012-10-31 帕尔萨维斯库勒公司 Systems and methods for enclosing an anatomical opening
CN103237526A (en) * 2010-12-06 2013-08-07 科维蒂恩有限合伙公司 Vascular remodeling device
CN102764170A (en) * 2012-07-18 2012-11-07 吕文峰 Intravascular stent with complex functions
CN104736071A (en) * 2012-08-22 2015-06-24 菲诺克斯有限公司 Implant
CN204814292U (en) * 2015-07-23 2015-12-02 高不郎 A top tectorial membrane support for cerebral artery crotch aneurysm

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901794A (en) * 2017-03-03 2017-06-30 高不郎 Aneurysm clip for treating the arterial side wall with vessel branch and terminal aneurysm

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Application publication date: 20151118