CN105053410A - Medicinal compound chrysanthemum tea and preparation method thereof - Google Patents

Medicinal compound chrysanthemum tea and preparation method thereof Download PDF

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CN105053410A
CN105053410A CN201510528647.6A CN201510528647A CN105053410A CN 105053410 A CN105053410 A CN 105053410A CN 201510528647 A CN201510528647 A CN 201510528647A CN 105053410 A CN105053410 A CN 105053410A
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fruit
chrysanthemum
glossy privet
medicinal compound
chrysanthemum tea
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蒋传中
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Abstract

The present invention discloses a medicinal compound chrysanthemum tea and a preparation method thereof, and relates to the field of medical care. In view of shortcomings of the prior western medicine treatment for diabetes combined with eye disease and hyperlipidemia, the provided medicinal compound chrysanthemum tea is harmless to the human body, and can effectively treat patients with diabetes combined with eye disease and hyperlipidemia for long-term use. The medicinal compound chrysanthemum tea consists of Chinese wolfberry fruits 10-18 grams, fructus corni 8-12 grams, yellow rice wine simmered fructus ligustri lucidi 8-12 grams and chrysanthemum 8-12 grams. The formulation uses treatment principles of comprehensively conditioning body, addressing both symptoms and root causes, and strengthening body resistance and eliminating pathogenic factors, and can lower blood viscosity, regulate microcirculation, regulate organ function and regulate yin and Yang balance to realize effects in nourishing liver and kidney, promoting saliva secretion and improving eyesight, and lowering blood sugar and blood lipid. The medicinal compound chrysanthemum tea is suitable for patients with diabetes combined with eye disease and hyperlipidemia, and also has treatment effects for dizziness and blurred vision, soreness and weakness of waist and knees, visual deterioration, dry eyes and unclear vision at the same time.

Description

A kind of medicinal compound chrysanthemum tea and preparation method thereof
Technical field
The present invention relates to field of food, particularly relate to a kind of chrysanthemum tea.
Background technology
Diabetes are a kind of common endocrine system diseases, and the traditional Chinese medical science is referred to as diabete, and it can cause many chronic complicating diseases, and Eye disease is one of modal chronic complicating diseases of diabetes.
Nearly all illness in eye all may occur in it diabetic, and as optical fundus blood vessel knurl, fundus hemorrhage, glaucoma, cataract etc., and diabetic the probability of these illness in eye occurs apparently higher than non-diabetic people.
Current treatment diabetes merge illness in eye and mainly adopt western medicine, and conventional Western medicine has pancreatic kallikrein, Methycobal and calcium dobesilate etc.But Western medicine lacks Overall View, cure the symptoms, not the disease.Meanwhile, because the hyperglycaemia that diabetic eye patient is long-term causes the impaired organ such as the heart, liver kidney, and Western medicine more can increase the weight of infringement, causes cardio cerebrovascular affection, kidney failure etc.
Diabetes are organism metabolic disorder inherently, except abnormal carbohydrate metabolism, also with fat, protein, water, electrolytical metabolic disorder, often has free fatty to dissociate out from fat depot, triglyceride and FFA concentrations in blood are increased.When the insufficient insulin of diabetic, in body, lipid metabolism enzyme also can reduce, and therefore causes blood fat to raise.Diabetes insulin shortage can cause high fat of blood, and contrary high fat of blood also can increase the weight of the state of an illness of diabetes.Diabetic is in hyperglycemia state for a long time in addition, easily cause hyperlipidemia, and hyperlipidemia directly can cause the disease of some serious harm healths, as atherosclerotic, coronary heart disease, pancreatitis etc., the medicine of current treatment hyperlipidemia has Statins and resinae based on what reduce serum total cholesterol and LDL-C, the special class of shellfish and nicotinic acid class is had based on the medicine reducing serum triacylglycerol, the shortcoming that same existence is cured the symptoms, not the disease, and Western medicine long-term taking easily causes other to affect on human body, is detrimental to health.
Summary of the invention
The object of the invention is the shortcoming existed for above-mentioned Western medicine, provide a kind of Long-Time Service harmless, effectively can treat diabetes patient and produce Eye disease and hyperlipidemia, there is medicinal compound chrysanthemum tea of the effect for the treatment of both principal and secondary aspect of disease and preparation method thereof.
The invention provides a kind of medicinal compound chrysanthemum tea, be made up of the fruit of Chinese wolfberry 10 ~ 18g, Fructus Corni 8 ~ 12g, the wine fruit of glossy privet 8 ~ 12g, chrysanthemum 8 ~ 12g;
The described wine fruit of glossy privet be get the fruit of glossy privet and its mass fraction be 20% yellow rice wine stir and be placed in closed container, logical steamed exhausts completely to yellow rice wine, dries, obtains the wine fruit of glossy privet.
Preferably, this medicinal compound chrysanthemum tea is made up of fruit of Chinese wolfberry 15g, Fructus Corni 10g, wine fruit of glossy privet 10g, chrysanthemum 10g.
The present invention also provides above-mentioned medicinal compound chrysanthemum tea preparation method, get the fruit of Chinese wolfberry, Fructus Corni, the wine fruit of glossy privet clean, add water 1500ml, and the boiled rear little fire of big fire boils 15min, then add chrysanthemum and boil 5min, pour out decocting liquid, decoct residue and add 800ml water, boil 10min again after boiled, obtain secondary decocting liquid, get twice decocting liquid mixing, obtain chrysanthemum tea.
Take at twice when this medicinal compound chrysanthemum tea is taken, every day potion, day takes twice, and one week is a course for the treatment of, and January takes effect.
The pharmacological effect of each composition of the present invention is:
Traditional Chinese medical science foundation:
1, fruit of Chinese wolfberry taste is sweet, property flat, returns liver, kidney channel.Effect is nourishing liver and kidney, benefiting shrewd head, and for the deficiency of liver-yin and kidney-yin, consumptive disease essence is lost, soreness of waist and knee joint, dizzy tinnitus, impotence and seminal emission, and interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is not clear waits disease.
2, Fructus Corni taste is sour, puckery, slightly warm in nature.Return liver, kidney channel.Have and tonify the liver and kidney, effect that puckery essence takes off admittedly.Under being used for the treatment of dizzy tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, uterine bleeding band, profuse sweating collapse, interior heat quenches one's thirst.
3, fruit of glossy privet bitter but sweet flavor is put down, and returns liver, kidney channel.Function: filling liver kidney, strong waist knee, the cloudy order of heat-clearing.Cure mainly: yin asthenia generating intrinsic heat, dizziness, order flower, tinnitus, soreness and weakness of waist and knees, poliosis.
4, chrysanthemum taste is sweet, bitter, cold nature.Return lung, Liver Channel.Effect: loose wind heat-clearing, flat liver improving eyesight.For anemopyretic cold, have a headache dizzy, red eye, swell pain, eyes is dim-sighted.
Modern pharmacology foundation:
1, the fruit of Chinese wolfberry
The fruit of Chinese wolfberry contains sweet benzene alkali, LBP-X, Liang Mu booth, free amino acid, vitamin and various trace elements.Main pharmacological has:
(1) hypoglycemic.The fruit of Chinese wolfberry has hypoglycemic activity significantly, can repair the regeneration of impaired B cell.Fructus lycii P.E can reduce rat blood sugar, increase sugar tolerance, and this is relevant with the derivative contained in the fruit of Chinese wolfberry.LBP-X can reduce intact animal blood sugar, has obvious prevention effect to the animal diabetes that alloxan causes.In addition, LBP-X has alpha-glucosaccharase and has stronger non-competitive inhibition.
(2) reducing blood lipid.The fruit of Chinese wolfberry obviously reduces the effect of serum TC, TG, LDL-C and hepatic tissue TC, TG.The blood lipid level of LBP-X functions for the treatment of hyperlipidemia mouse.
2, Fructus Corni
Fructus Corni main component has cornin, morroniside, loganin, river deer tooth Zhu glycosides, the new glycosides of Fructus Corni, also has tannin, ursolic acid, gallic acid, malic acid, oleanolic acid, tartaric acid and vitamin A.Main pharmacological:
(1) resisting stress, anti-oxidant, reducing blood lipid.Fructus Corni can strengthen the anti-stress ability of body, improves mouse resist oxygen lack, anti-fatigue ability, strengthens memory.SOD in red blood cell can be improved active, to anti peroxidation of lipid.Its alcohol extract also has the effect of reducing blood lipid, can reduce the content of serum triglyceride, cholesterol, has anti arteriosclerosis effect.
(2) hypoglycemic and anti-diabetic vascular lesion.Fructus Corni hypoglycemic activity is obvious, has obvious hypoglycemic activity to alloxan, the sick rat of epinephrine glycosuria.Ingredient ursolic acid and oleanolic acid cause the sick rat of syrup to Streptozotocin also has therapeutic action.Cornusol extract also obviously affects rat blood sugar, but can obviously reduce its level of postprandial blood sugar.What be separated from Fructus Corni has good α-glucosidase inhibitory active with tannin.Cornel iridoid glycoside has protective effect to the pathology damage such as rat chest aorta blood vessel endothelium, retinal vessel, heart, kidney caused by Streptozotocin, and its formula composition (iridoid glycoside, triterpenic acid and polysaccharide) effect is more obvious.Its mechanism of action with anti-oxidant, CKIs matter non-enzymatic glycation is relevant.Hypoglycemic, the Antiaggregating activity on platelet of Fructus Corni energy, reduces blood viscosity, resists peroxide injury, alleviates the Cardiovascular Damage of diabetic.
3, the fruit of glossy privet
The fruit of glossy privet contains oleanolic acid, acetyloleanolic acid, ursolic acid, sweet mellow wine, glucose, palmitic acid, stearic acid, oleic acid, linoleic acid.Main pharmacological has:
(1) function of blood sugar reduction, with fruit of glossy privet water decoction 15.30g/kg to mouse stomach 10d, can reduce the blood sugar of normal mouse, have prophylactic treatment effect to the diabetes that alloxan causes.And the blood sugar that can cause antiadrenergic drug or glucose raises, in fruit of glossy privet pericarp, content of oleanolic acid is up to 14%, and oleanolic acid has obvious hypoglycemic activity, therefore infers, oleanolic acid is the hypoglycemic important component of the fruit of glossy privet.
(2) immunity function is strengthened.With tetramethyl azo mouth raw salt (MTT) colorimetric analysis, carry out immunocompetence inside and outside Mice Body to Fructus Ligustri Lucidi polysaccharide composition to observe, found that, Fructus Ligustri Lucidi polysaccharide has significant facilitation to lymphocyte under the spleen of the deficiency of Yin mouse of normal mouse and cortex hormone of aadrenaline moulding.
Application 3H-TdR incorporation methods detects Fructus Ligustri Lucidi polysaccharide (LLS) the external impact on mouse immune cell proliferation.The Fructus Ligustri Lucidi polysaccharide of experimental result display 156-1250ug/ml, to normal mouse spleen lymphocyte (B cell) and the splenocyte (T cell) by nylon hair post, all has the effect of directly stimulating proliferation.Dose-effect relationship is obvious, and macrophage plays certain auxiliary use in splenic lymphocytes.
Above mouse immune organ, the Congo red amount of cleaning up, lymphocyte transformation rate, serum hemolysis cellulose content are index, the immunization comparing the different processed product of the fruit of glossy privet is strong and weak, experimental result shows, it is strong that the wine of the fruit of glossy privet steams product to the comparatively steamed product of mouse immune system regulating action, raw product.
(3) hypolipemic function.Every day gavages the lard containing cholesterol to rabbit, makes blood fat maintain about 540mg/100ml after 45d, then feeding fruit of glossy privet meal, every 20g/d.After treatment, 30g serum cholesterol amount is obviously reduced to 417mg/100ml, and serum triglyceride content is significantly reduced.Consumption is formed to the formation of experimental sustainer Lipid Plaque and Atherosclerotic Vessels: Changes Observed during Coronary.
Only, administration every day 2 times after rabbit Experimental Hyperlipemia moulding 46d, result shows fruit of glossy privet meal 30g/, and the fruit of glossy privet has reduction filling to raise cholesterol, the formation of Aorta atheromatous plague, reduces coronary artery disease parameter and lesion degree.Serum total cholesterol, triglycerides can be obviously reduced, increasing serum HDL to hyperlipidemia patient.
4, chrysanthemum
Chrysanthemum is mainly containing volatile oil (camphor, borneol, Bronyl acetate etc.), and (this rhinoceros grass is plain for flavones ingredient, luteolin-7-glucoside, perverse Chinese scholartree element etc.), stachydrine, choline, adenine, vitamin B1 vitamin A, amino acid, its main pharmacological has:
(1) resisting pathogenic microbes.In chrysanthemum body, outer all have good pressing down for effect.Volatile oil has stronger inhibitory action to staphylococcus aureus, Escherichia coli, shigella flexneri etc.Chrysanthemum has antivirus action, and chrysanthemum high concentration water decocting liquid has resisiting influenza virus effect in body, the strongest with cyanidenon effect.
(2) can heat, antiinflammatory action.Chrysanthemum concrete gavage, have refrigeration function to artificial fever rabbit, the mechanism of action is relevant with Central nervous depressant; Anti-inflammatory main matter basis is triterpene compound.
(3) to Cardiovascular.Chrysanthemum preparation energy coronary artery dilating, alleviates myocardial ischemia.
(4) reducing blood lipid.To feed high lipid food to SD rat, by chrysanthemum water extract gavage, can suppress the rising of serum cholesterol and three oily sweet esters, for normal basal feed rat, chrysanthemum can keep serum total cholesterol substantially constant, improves the HDL concentration having protective effect.Reduce harmful LDL concentration, under high fat rises food situation, there is the effect suppressing cholesterolemia and triglycerides to raise.
The present invention has following beneficial effect:
The present invention adopts overall conditioning, strengthening vital QI to eliminate pathogenic factors, the principle of reatment for the treatment of both principal and secondary aspect of disease, reduces blood viscosity, regulates microcirculation, regulate organ function, regulate equilibrium between yin and yang, reach nourishing liver and kidney, improving eyesight of promoting the production of body fluid, effect of hypoglycemic, reducing blood lipid, merging illness in eye, hyperlipidemia to being applicable to diabetes, having that treatment is had a dizzy spell simultaneously concurrently, soreness and weakness of waist and knees, hypopsia, two dry and astringent, blurring of vision effect.
Detailed description of the invention
The present invention side of formula solution:
1, in side, the monarch drug in a prescription fruit of Chinese wolfberry is sweet flat moist, enters liver kidney channel.For nourishing liver and kidney, nourish blood and mend the good medicine of essence, improving eyesight, kind control the having a dizzy spell of kidney deficiency and liver, soreness and weakness of waist and knees, hypopsia and the card such as to quench one's thirst.The fruit of Chinese wolfberry contains abundant polysaccharide by improving Pancreatic beta cells function, increases insulin sensitivity, increases the deposit of hepatic glycogen, reduces blood sugar level.In addition, also significantly serum cholesterol can be reduced, the content of serum triglyceride.
2, the sour and astringent and tepor of Fructus Corni, enters liver kidney channel, can moisten the moon of nourishing liver and kidney, again can warming and invigorating kidney Yang, and be the key medicine of flat tonifying yin sun, this product and nourishing Yin and promoting production of body fluid fruit of Chinese wolfberry compatibility, can control diabete.Hypoglycemic, the Antiaggregating activity on platelet of energy, reduces blood viscosity, resists peroxide injury, alleviates the Cardiovascular Damage of diabetic; Its alcohol extract also has the effect of reducing blood lipid, can reduce the content of serum triglyceride, cholesterol, has anti arteriosclerosis effect.
3, fruit of glossy privet sweetness and bitterness is cool, enters liver, kidney channel.There is tonifying liver kidney yin and crow palpus, improving eyesight, the effect of bringing down a fever.With the order the controlling the deficiency of liver-yin and kidney-yin secretly card such as not clear, poliosis and fever due to yin deficiency.This product Aqueous extracts, Fructus Ligustri Lucidi polysaccharide and oleanolic acid have the effect strengthening immunologic function.Oleanolic acid also has protecting liver, lowering enzymes, antiatherosclerosis, reducing blood lipid, hypoglycemic activity.
4, chrysanthemum.Acrid-sweet flavor hardship, cold nature, return lung, Liver Channel.There is the effect of evacuating wind, heat, the clear sharp head, suppressing liver-YANG, cure mainly wind-heat illness that has not attacked the vital organs of the human body, head Zhu Ji, sore, ear nose are unfavorable, clinical efficacy is mainly reflected in " dispelling wind heat ", " refresh oneself ", aspect, the chrysanthemum such as " eye-candy blood " and " removing toxic substances expels the heat-evil " " can remove screen film, improving eyesight ", again can " foster order blood ", " tonifying yin ", for " order section key medicine ", clinical normal reasonable compatibility treatment actual situation order disease.Flavone compound in chrysanthemum, has the effect of Antiaggregating activity on platelet, can also reduce T-CHOL, triglycerides, low-density lipoprotein, has certain Regulation serum lipids to hyperlipidemia, can also suppress the formation of external thrombus in addition.
Below in conjunction with specific embodiment, the present invention will be further described.
In following embodiment, wine fruit of glossy privet preparation method is that the yellow rice wine getting the fruit of glossy privet and its mass fraction 20% stirs and is placed in closed container, and logical steamed exhausts completely to yellow rice wine, dries, when fruit of glossy privet outward appearance black profit, obtains the wine fruit of glossy privet.
Embodiment 1
Get fruit of Chinese wolfberry 10g, Fructus Corni 8g, wine fruit of glossy privet 8g, chrysanthemum 8g.
By the 1500ml that adds water after the fruit of Chinese wolfberry, Fructus Corni, the cleaning of the wine fruit of glossy privet, the boiled rear little fire of big fire boils 15min, boils 5min again, pour out decocting liquid after adding chrysanthemum, add 800ml water again, boil 10min again after boiled, get twice decocting liquid mixing, take at twice, every day potion, day takes twice, and one week is a course for the treatment of, and January takes effect.
Embodiment 2
Get fruit of Chinese wolfberry 18g, Fructus Corni 12g, wine fruit of glossy privet 12g, chrysanthemum 12g.
By the 1500ml that adds water after the fruit of Chinese wolfberry, Fructus Corni, the cleaning of the wine fruit of glossy privet, the boiled rear little fire of big fire boils 15min, boils 5min again, pour out decocting liquid after adding chrysanthemum, add 800ml water again, boil 10min again after boiled, get twice decocting liquid mixing, take at twice, every day potion, day takes twice, and one week is a course for the treatment of, and January takes effect.
Embodiment 3
Get fruit of Chinese wolfberry 15g, Fructus Corni 10g, wine fruit of glossy privet 10g, chrysanthemum 10g.
By the 1500ml that adds water after the fruit of Chinese wolfberry, Fructus Corni, the cleaning of the wine fruit of glossy privet, the boiled rear little fire of big fire boils 15min, boils 5min again, pour out decocting liquid after adding chrysanthemum, add 800ml water again, boil 10min again after boiled, get twice decocting liquid mixing, take at twice, every day potion, day takes twice, and one week is a course for the treatment of, and January takes effect.
Above content is the further description done the present invention in conjunction with concrete embodiment, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made, all should be considered as belonging to protection scope of the present invention.

Claims (3)

1. a medicinal compound chrysanthemum tea, is characterized in that: be made up of the fruit of Chinese wolfberry 10 ~ 18g, Fructus Corni 8 ~ 12g, the wine fruit of glossy privet 8 ~ 12g, chrysanthemum 8 ~ 12g;
The described wine fruit of glossy privet be get the fruit of glossy privet and its mass fraction be 20% yellow rice wine stir and be placed in closed container, logical steamed exhausts completely to yellow rice wine, dries, obtains the wine fruit of glossy privet.
2. medicinal compound chrysanthemum tea as claimed in claim 1, is characterized in that: be made up of fruit of Chinese wolfberry 15g, Fructus Corni 10g, wine fruit of glossy privet 10g, chrysanthemum 10g.
3. a medicinal compound chrysanthemum tea preparation method as claimed in claim 1 or 2, it is characterized in that: get the fruit of Chinese wolfberry, Fructus Corni, the wine fruit of glossy privet clean, add water 1500ml, and the boiled rear little fire of big fire boils 15min, then add chrysanthemum and boil 5min, pour out decocting liquid, decoct residue and add 800ml water, boil 10min again after boiled, obtain secondary decocting liquid, get twice decocting liquid mixing, obtain chrysanthemum tea.
CN201510528647.6A 2015-08-26 2015-08-26 Medicinal compound chrysanthemum tea and preparation method thereof Pending CN105053410A (en)

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* Cited by examiner, † Cited by third party
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CN105379911A (en) * 2015-11-30 2016-03-09 全椒县周杨农业有限公司 Preparation method of nourishing chrysanthemum tea
CN108477342A (en) * 2018-03-30 2018-09-04 安徽丰穗农业开发有限公司 A kind of fat reducing decompression chrysanthemum tea and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105379911A (en) * 2015-11-30 2016-03-09 全椒县周杨农业有限公司 Preparation method of nourishing chrysanthemum tea
CN108477342A (en) * 2018-03-30 2018-09-04 安徽丰穗农业开发有限公司 A kind of fat reducing decompression chrysanthemum tea and preparation method thereof

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Application publication date: 20151118