CN105046881A - Alarm against tumble of elder - Google Patents

Alarm against tumble of elder Download PDF

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Publication number
CN105046881A
CN105046881A CN201510301128.6A CN201510301128A CN105046881A CN 105046881 A CN105046881 A CN 105046881A CN 201510301128 A CN201510301128 A CN 201510301128A CN 105046881 A CN105046881 A CN 105046881A
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CN
China
Prior art keywords
falls
old people
key
alarm
series monolithic
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Pending
Application number
CN201510301128.6A
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Chinese (zh)
Inventor
孙斌
张新财
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ZHEJIANG HELLOWIN MEDICAL TECHNOLOGY Co Ltd
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ZHEJIANG HELLOWIN MEDICAL TECHNOLOGY Co Ltd
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Priority to CN201510301128.6A priority Critical patent/CN105046881A/en
Publication of CN105046881A publication Critical patent/CN105046881A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G08SIGNALLING
    • G08BSIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
    • G08B21/00Alarms responsive to a single specified undesired or abnormal condition and not otherwise provided for
    • G08B21/02Alarms for ensuring the safety of persons
    • G08B21/04Alarms for ensuring the safety of persons responsive to non-activity, e.g. of elderly persons
    • G08B21/0407Alarms for ensuring the safety of persons responsive to non-activity, e.g. of elderly persons based on behaviour analysis
    • G08B21/043Alarms for ensuring the safety of persons responsive to non-activity, e.g. of elderly persons based on behaviour analysis detecting an emergency event, e.g. a fall
    • GPHYSICS
    • G08SIGNALLING
    • G08BSIGNALLING OR CALLING SYSTEMS; ORDER TELEGRAPHS; ALARM SYSTEMS
    • G08B25/00Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems
    • G08B25/01Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems characterised by the transmission medium
    • G08B25/08Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems characterised by the transmission medium using communication transmission lines

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  • Health & Medical Sciences (AREA)
  • Business, Economics & Management (AREA)
  • Emergency Management (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Alarm Systems (AREA)

Abstract

The invention relates to an alarm against tumble of the elder and an alarming system of the alarm. The alarming system is composed of a sensing unit, a microprocessor unit and a wireless communication module; and is characterized in that the microprocessor unit mainly comprises a single-chip microcomputer of the series of SMT32 with a peripheral data memory, peripheral equipment of the single-chip microcomputer includes an A/D converter, a high-speed SPI bus and a USART interface, the single-chip microcomputer internally includes a DMA channel, the A/D converter is connected with a tri-axis accelerometer and a dual-axis gyroscope via two external low-pass filter circuits respectively, the tri-axis accelerometer and the dual-axis gyroscope form the sensing unit, and the single-chip microcomputer is connected to a host computer which can upload processed data via the wireless communication module. The alarm is exquisite in design, diverse in functions, accurate in information and suitable for the industry of electronic products.

Description

A kind of Falls in Old People alarm
Technical field
What the present invention relates to is a kind of Falls in Old People alarm, belongs to safeguard and supervision for the aged health care technology field.
Background technology
Falling is serious threat to senior health and fitness and even life, also brings white elephant to society.In China, falling is the over-65s the elderly first place injury cause of the death.Obtain the fall kinematic data of behavior of human body by multisensor to carry out accurately identifying and timely early warning, thus the injury that reduction Falls in Old People brings is significant.
At present, mainly there is the problem of following two aspects in fall alarm accurately: (1) fall report to the police not accurate; (2) product device function singleness.
In prior art, the automatic testing method for Falls in Old People mainly contains 3 kinds: 1) detected by video; 2) audio frequency and Vibration identification; 3) by the device of body-worn, they immediately can detect and fall.3rd kind of method uses simple, cheap, is easy to combine with existing wireless communication technology, intelligent identification technology etc., thus reaches good detection/warning effect.System wherein based on three-dimensional acceleration sensing becomes the main trend studying fall detection at present both at home and abroad, and acceleration rate threshold is modal decision procedure of falling.But because human body daily behavior Comparison of Gardening Activities is complicated, there is erroneous judgement in various degree in actual applications according to the distinguished number of falling of priori threshold value, the simple information according to acceleration transducer is difficult to the accurate judgement carrying out behavior of falling.
To fall warning out of true.Show that with the recognizer of falling of 3-axis acceleration sensor, dual spindle gyroscopes, microprocessor and wireless communication module behavior of the falling real-time detecting system that is core be not very accurate, especially show the detection algorithm under roll-over state, error is larger.
Product device function singleness shows that most of fall alarm only has a warning function in the market, and this is not enough far away for being used in old man's product function.
Summary of the invention
The object of the invention is to the deficiency overcoming prior art existence, and provide a kind of structure to form rationally, easy to use and reliable, the degree of accuracy of reporting to the police can be improved, expand the Falls in Old People alarm of use subsidiary function.
The object of the invention is to have come by following technical solution, a kind of Falls in Old People alarm, it comprises in one the housing being provided with Falls in Old People warning system, and described housing upper front is provided with LED display, and a side end edge is provided with earpiece holes and power switch; Front, middle part is provided with word tag plug-in card; Front, bottom is separately installed with various function key; The reverse side of bottom is at least configured with battery cover, and inside is correspondingly provided with the battery case being provided with battery.
The limit, upper end of described housing is provided with link; Described various function keys at least comprise: the key that receives calls, emotional affection assignment key, note check key, sound adjusting key, screen intensity adjusting key and phone on-hook key, separately the side of housing are provided with Medical Devices interface and charging socket.
Falls in Old People warning system primarily of sensing unit, microprocessor unit and wireless communication module composition is installed in described housing, wherein said microprocessor unit mainly comprises the SMT32 series monolithic being furnished with data-carrier store outside, be provided with A/D converter, high speed SPI bus and USART interface outside this SMT32 series monolithic, bus on chip comprises DMA passage; Described A/D converter is connected with 3-axis acceleration sensor and dual spindle gyroscopes respectively by external two-way low-pass filter circuit, and described 3-axis acceleration sensor and the sensing unit described in dual spindle gyroscopes formation; Described SMT32 series monolithic is connected to the host computer of data upload that can will handle well by wireless communication module;
Described SMT32 series monolithic is also connected to LCD display, button, bluetooth, ACPS module, by voicefrequency circuit external loudspeaker and receiver; Described SMT32 series monolithic is connected with the charge power supply of a configuration SIM card.
Described dual spindle gyroscopes selects double-shaft MEMS gyroscope IDG-300 of InvenSense company, and its range is ± 500 °/s; Described 3-axis acceleration sensor adopts the 3 axis MEMS acceleration transducer MMA7260Q of TM, and its maximum range is ± 6gn; When ± 6gn range, sensitivity is 200mV/g.
The invention has the beneficial effects as follows: compare fall alarm precision common in the market and significantly improve, reliability reaches 87.63%.The multiple utility function newly increased, the feature of the portable easy operation required according to most of man at an advanced age is arranged; It has structure composition rationally, easy to use and reliable, can improve the degree of accuracy of reporting to the police, and expands features such as using subsidiary function.
Accompanying drawing explanation
Fig. 1 is the Facad structure schematic diagram of Falls Among Old People alarm of the present invention.
Fig. 2 is the inverse layer structure schematic diagram of Falls Among Old People alarm of the present invention.
Fig. 3 is the circuit logic schematic diagram of Falls Among Old People alarm of the present invention.
Fig. 4 is the logical diagram of Falls Among Old People recognizer of the present invention.
Embodiment
Below in conjunction with the drawings and specific embodiments, the present invention will be described in detail.Shown in Fig. 1,2, a kind of Falls in Old People alarm, it comprises in one the housing 15 being provided with Falls in Old People warning system, and described housing 15 top front face is provided with LED display 6, and limit, upper end is provided with earpiece holes 16, and a side is provided with power switch 17; Front, middle part is provided with word tag plug-in card 18; Front, bottom is separately installed with various function key; The reverse side of bottom is at least configured with battery cover 19, and inside is correspondingly provided with the battery case 21 being provided with battery 20.
Shown in figure, in the middle of the limit, upper end of described housing 15, link 22 is installed; Described various function keys at least comprise: the key 23 that receives calls, emotional affection assignment key 24, note check key 25, sound adjusting key 26, screen intensity adjusting key 27 and phone on-hook key 28, separately the side of housing are provided with Medical Devices interface 29 and charging socket 30 etc.
Shown in Fig. 3, a kind of Falls in Old People warning system of the present invention, it forms primarily of sensing unit, microprocessor unit and wireless communication module, described microprocessor unit mainly comprises the SMT32 series monolithic 1 being furnished with data-carrier store 14 outside, be provided with A/D converter 2, high speed SPI bus and USART interface outside this SMT32 series monolithic 1, bus on chip comprises DMA passage; Described A/D converter 2 is connected with 3-axis acceleration sensor 4 and dual spindle gyroscopes 5 respectively by external two-way low-pass filter circuit 3, and described 3-axis acceleration sensor 4 and dual spindle gyroscopes 5 form described sensing unit; Described SMT32 series monolithic 1 is connected to the host computer of data upload that can will handle well by wireless communication module.
Shown in figure, described SMT32 series monolithic 1 is also connected to LCD display 6, button 7, bluetooth 8, ACPS module 9, by voicefrequency circuit 10 external loudspeaker and receiver 11; Described SMT32 series monolithic 1 is connected with the charge power supply 13 of a configuration SIM card 12.
Specific embodiments of the invention are: described dual spindle gyroscopes 5 selects double-shaft MEMS gyroscope IDG-300 of InvenSense company, its range to be ± 500 °/s; Described 3-axis acceleration sensor 4 adopts the 3 axis MEMS acceleration transducer MMA7260Q of TM, and its maximum range is ± 6gn; When ± 6gn range, sensitivity is 200mV/g.
A kind of alarm method utilizing described Falls in Old People warning system to carry out, described alarm method is: based on the recognizer of falling of human motion characterisitic parameter, 3-axis acceleration sensor is utilized to monitor acceleration signature, utilize the change of dual spindle gyroscopes monitoring angle speed, receive accekeration and magnitude of angular velocity by the STM series monolithic be connected and extract characteristic quantity as basis for estimation, the magnitude of angular velocity monitored in time by angular-rate sensor is distinguished as fall sign and daily routines, and judge finally whether fall in conjunction with the posture analysis that acceleration signal obtains, and report to the police after judgement is fallen.
Described recognizer of falling is: first set up human body coordinate system, can produce larger difference in the process of falling with between standard reference system; Fall in process at human body, no matter towards which direction, the speed of vertical direction and position can change, and acceleration and the angle of depression also all can produce change in a big way, and therefore, extracting characteristic quantity with accekeration and magnitude of angular velocity can as the foundation judged;
By to the analysis of falling down data, the design of threshold value diagnostic method is adopted to fall down detection algorithm, α nfor resultant acceleration value, θ is the value of the angle of pitch, and θ is current time relative to the recruitment of the angle of pitch starting to judge the moment.Minimal value when threshold value thresholding FT1 is for falling down, gets 0.20g n; To fall down in process accekeration within a certain period of time to increase rapidly, the angle of pitch also can increase simultaneously, makes threshold value FT2 be taken as 3.90g n; Threshold value FT3 gets 4.80g n, increase at the angle of pitch and approach to 75 .time, can be judged to fall down more than the situation of FT3.As shown in Figure 4.
The present invention is the technique improvement carried out on the basis of existing technology; what the angle information of human motion judged as behavior of falling by it effectively supplements; construct with 3-axis acceleration sensor MMA7260Q; dual spindle gyroscopes IDG-300; STM32 microprocessor and wireless communication module are behavior of the falling real-time detecting system of core; and utilize the model machine of development to carry out human body daily routines and the research of behavior of falling, propose the recognizer of falling based on human body motion feature parameter.
Sensing unit selection and arrangement.Acceleration signature is an Important Parameters in human body motion feature, during human normal walking, acceleration periodically rule change, and falling the moment, acute variation can be there is in acceleration, the change of acceleration can reflect the change of human motion state, therefore, adopt 3-axis acceleration sensor monitoring acceleration signature, old man is before causing danger property is fallen, there will be a series of warning, the particularly sense of equilibrium worse and worse.The basic characteristics of the elderly's gait are that lower limb muscles convergent force declines, and heelstrike, ankle, knee flexing are slow in one's movements, stretch hip insufficient, and cause walking slowly, stride shortens, and walks discontinuous, and pin can not be lifted to a suitable height; Utilize angular-rate sensor to detect in time to fall sign and distinguish with daily routines.In the process of falling, the change of the angle of pitch is the most obvious, and in addition, the attitude after falling down to the ground is relevant with flip angle, therefore, adopt the change of dual spindle gyroscopes detection angle speed.
Partial function is added: comprise in the technical solution adopted in the present invention receive calls close phone sOS emotional affection is called out note is checked screen intensity manual adjustments sound manual adjustments function of passometer shows blue-teeth data interface.
Microprocessor unit of the present invention: the STM32 series monolithic based on Cortex-M3 kernel adopting ST company, its framework is advanced, and core frequency 72MHz, can meet the requirement of data processing.Peripheral hardware contains high performance 12 high-speed a/d converters and high speed SPI bus, the multiple bus interfaces such as USART interface.Bus on chip has DMA passage, and the data obtained from A/D converter can directly be sent to each bus interface and not need CPU to intervene.
In system acquisition pattern, in order to analyze the change of each sensor signal in the process of falling, need the raw data of sensor is stored and is sent to host computer analysis.In the process of image data, original data volume is large, may occur packet loss phenomenon, therefore, need the raw data of data storage cell record sensor in wireless module transmitting procedure.
The plug of SD card is convenient, cheap, is suitable for as portable memory apparatus, adopts SD card as storage unit at this.Be connected with STM32 single-chip microcomputer by spi bus, open DMA passage, the transformation result of A/D converter directly can be sent on spi bus, thus reduce kernel for carrying the time of data.
The present invention adds wireless communication module in systems in which, open wireless communication under proof of algorithm pattern, the real-time process sensor data of system, and the data handled well are sent to host computer by wireless module, once detect and fall, sends alerting signal immediately.Wireless module uses NF905 finished product module.
System software of the present invention, based on the STM32 standard peripherals storehouse of ST company, adopts hierarchy to write.Realize signalling channel to select to change with A/D, data processing, control wireless module data and send, SD card data store, the tasks such as duty selection.The hierarchical chart of system software as shown in Figure 2.The software interface standard of the Cortex microprocessor that (cortexmicro-controllersoftwareinterfacestandard, CMSIS) provides for ARM, provides the general-purpose interface that kernel and peripheral hardware, real-time oss are unified between middleware equipment.Provide the bus level handling function for MCU peripheral hardware in STM32 standard peripherals storehouse, write bus driver on this basis, realize initial configuration and the basic operation of each bus.By calling the driving function of bus driver function programming apparatus level, provide the operation of each module,
Realize the modularization of software.Transplant embedded Fatfs file system simultaneously, the sensing data collected directly is stored in SD card with text formatting, can direct read data files on computers.Application program utilization state machine thought realizes, and is acquisition state and low power consumpting state, and in acquisition state, divides multiple sub-state, carried out the task operating of being correlated with by the redirect of state by system divides
In actual product use procedure, first lay down bonnet from the back side of model machine, insert SIM card, then rechargeable battery and bonnet are installed.Turn on the power switch, LCD screen starts to show start picture, after picture has started, namely enters duty.SOS call number (being no more than at most 3) is first set, passometer display mode, alarm parameters of falling, AGPS automatic uplink time cycle, bluetooth joint mode etc. are set after then suitable screen intensity, sound are set again.After various optimum configurations completes, namely enter normal operating conditions.

Claims (5)

1. a Falls in Old People alarm, it comprises in one the housing being provided with Falls in Old People warning system, and it is characterized in that described housing upper front is provided with LED display, a side end edge is provided with earpiece holes and power switch; Front, middle part is provided with word tag plug-in card; Front, bottom is separately installed with various function key; The reverse side of bottom is at least configured with battery cover, and inside is correspondingly provided with the battery case being provided with battery.
2. Falls in Old People alarm according to claim 1, is characterized in that the limit, upper end of described housing is provided with link; Described various function keys at least comprise: the key that receives calls, emotional affection assignment key, note check key, sound adjusting key, screen intensity adjusting key and phone on-hook key, separately the side of housing are provided with Medical Devices interface and charging socket.
3. Falls in Old People alarm according to claim 1 and 2, it is characterized in that the Falls in Old People warning system primarily of sensing unit, microprocessor unit and wireless communication module composition is installed in described housing, wherein said microprocessor unit mainly comprises the SMT32 series monolithic being furnished with data-carrier store outside, be provided with A/D converter, high speed SPI bus and USART interface outside this SMT32 series monolithic, bus on chip comprises DMA passage; Described A/D converter is connected with 3-axis acceleration sensor and dual spindle gyroscopes respectively by external two-way low-pass filter circuit, and described 3-axis acceleration sensor and the sensing unit described in dual spindle gyroscopes formation; Described SMT32 series monolithic is connected to the host computer of data upload that can will handle well by wireless communication module.
4. Falls in Old People alarm according to claim 3, is characterized in that described SMT32 series monolithic is also connected to LCD display, button, bluetooth, ACPS module, by voicefrequency circuit external loudspeaker and receiver; Described SMT32 series monolithic is connected with the charge power supply of a configuration SIM card.
5. Falls in Old People warning system according to claim 3, it is characterized in that described dual spindle gyroscopes selects double-shaft MEMS gyroscope IDG-300 of InvenSense company, its range is ± 500 °/s; Described 3-axis acceleration sensor adopts the 3 axis MEMS acceleration transducer MMA7260Q of TM, and its maximum range is ± 6gn; When ± 6gn range, sensitivity is 200mV/g.
CN201510301128.6A 2015-06-04 2015-06-04 Alarm against tumble of elder Pending CN105046881A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106887115A (en) * 2017-01-20 2017-06-23 安徽大学 Old people falling monitoring device and falling risk assessment method
CN111912433A (en) * 2020-07-14 2020-11-10 威步智能科技(苏州)有限公司 High-precision falling real-time judgment system

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201387660Y (en) * 2009-04-28 2010-01-20 中国科学院合肥物质科学研究院 Automatic detecting and alarming system for human body falling-over
CN103646506A (en) * 2013-11-14 2014-03-19 成都博约创信科技有限责任公司 Fall-down monitoring system with voice communication function
CN102750803B (en) * 2012-07-16 2014-04-16 深圳市富晶科技有限公司 Fall alarm, fall alarm detector and fall alarm detecting method
CN204044980U (en) * 2014-08-21 2014-12-24 昆山市华正电子科技有限公司 Multi-functional human body falling detection device and human body fall alarm
US20150145662A1 (en) * 2013-11-26 2015-05-28 Hti Ip, L.L.C. Using audio signals in personal emergency response systems
BR102013005618A2 (en) * 2013-03-08 2015-06-02 Toth Desenvolvimento Tecnológico Ltda One-user monitoring sensor system and same monitoring process

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201387660Y (en) * 2009-04-28 2010-01-20 中国科学院合肥物质科学研究院 Automatic detecting and alarming system for human body falling-over
CN102750803B (en) * 2012-07-16 2014-04-16 深圳市富晶科技有限公司 Fall alarm, fall alarm detector and fall alarm detecting method
BR102013005618A2 (en) * 2013-03-08 2015-06-02 Toth Desenvolvimento Tecnológico Ltda One-user monitoring sensor system and same monitoring process
CN103646506A (en) * 2013-11-14 2014-03-19 成都博约创信科技有限责任公司 Fall-down monitoring system with voice communication function
US20150145662A1 (en) * 2013-11-26 2015-05-28 Hti Ip, L.L.C. Using audio signals in personal emergency response systems
CN204044980U (en) * 2014-08-21 2014-12-24 昆山市华正电子科技有限公司 Multi-functional human body falling detection device and human body fall alarm

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106887115A (en) * 2017-01-20 2017-06-23 安徽大学 Old people falling monitoring device and falling risk assessment method
CN106887115B (en) * 2017-01-20 2019-05-10 安徽大学 Old people falling monitoring device and falling risk assessment method
CN111912433A (en) * 2020-07-14 2020-11-10 威步智能科技(苏州)有限公司 High-precision falling real-time judgment system

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