CN105028948A - Anti-aflatoxin mould inhibitor for aquatic feeds - Google Patents
Anti-aflatoxin mould inhibitor for aquatic feeds Download PDFInfo
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- CN105028948A CN105028948A CN201510369147.2A CN201510369147A CN105028948A CN 105028948 A CN105028948 A CN 105028948A CN 201510369147 A CN201510369147 A CN 201510369147A CN 105028948 A CN105028948 A CN 105028948A
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Abstract
The invention belongs to the technical field of feed mould prevention and particularly relates to an anti-aflatoxin mould inhibitor for aquatic feeds. The anti-aflatoxin mould inhibitor for the aquatic feeds is prepared from the components of 10ml/kg of fennel extracting solution, 10ml/kg of Chinese prickly ash extracting solution, 12ml/kg of pepper extracting solution, 10ml/kg of cleistocalyx operculatus bark extracting solution, 5ml/kg of origanum essential oil and 940g/kg of zeolite powder, wherein the zeolite powder serves as a carrier. The anti-aflatoxin mould inhibitor for the aquatic feed effectively solves the problem of pollution to the aquatic feeds by aflatoxin, and inhibits the growth of the aflatoxin in the aquatic feeds and injury to aquatic livestock.
Description
Technical field
The invention belongs to feedstuff mildew technical field, be specifically related to the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin.
Background technology
Mycotoxin was once described as " pestilence of the mankind ", recorded it and just existed since ancient times, but still have problems unresolved so far in Old Testament.Aflatoxin is mould contamination food, feedstuff, and toxic metabolic products main after other animal derived products.Many raw material of aquatic product feed stuff, as cottonseed, peanut, corn, soybean, paddy rice, dry fishes and shrimps, fish meal etc. and often can be infected by mycotoxin.At present, in aquaculture, the ratio of vegetality feedstuff is increasing, and this just exacerbates feed by the risk of mycotoxin contamination, and has the trend expanded further.Wherein, in most cases, in aquatic feeds, the pollution of aflatoxin is the most general, and particularly particularly serious under moist hot climatic environment condition, this climatic environment has caused the quick growth of mould.In addition, irrational Feedstock treating and storing mode are also important factors.Epidemiology survey shows, aflatoxin has potential harm to terrestrial animal and aquatic animal, has the residual of aflatoxin in the tissue of animal, or its metabolite, and this increases the threat to human health.Self-discovery aflatoxin is to since the harm of aquatic livestock, aflatoxicosis disease is more in the research of freshwater fish, be mainly concerned with rainbow trout (Oncorhynchusmykiss), America catfish (Ictaruluspunctatus), Tilapia mossambica (Oreochromisniloticus), India carp (Labeorohita), mosquito fish (Gambusiaaffinis), guppy fish (Lebistesreticulatus), and other invertebrate, as Penaeus monodon (Penaeusmonodon), very popular actor or actress prawn (Penaeusstylirostris), Penaeus Vannmei (Penaeusvannamei), fairy shrimp (Artemiasalina) and oar foot animal (Cyclopsfuscus) etc.Some summaries are had to aflatoxin before, class fungi produced aflatoxin (AF) four, classification position all belongs to Aspergillus belong to, but primarily of wherein 2 strains, namely Aspergillusflavus and Aspergillusparasiticus produces, and seldom originates from Aspergillusnomius and Aspergillusniger.Probably be separated 20 kinds of aflatoxin, and the wherein biological characteristics etc. of 4 kinds has been studied in detail.Wherein, A.parasiticus produces these whole 4 kinds, i.e. AFB1, AFB2, AFG1 and AFG24 kind aflatoxin, and A.flavus produces 2 kinds, i.e. AFB1 and AFB2.
In feed (raw material), part filamentous fungi or mould can produce poisonous compound, can produce murder by poisoning consequence after being eaten by mistake by human and animal.Most fungi can produce fungi (mould) toxin, becomes and produces malicious mould, and as Aspergillus, Penicillium, and Fusarium belongs to.The growth of mould and the generation of mycotoxin are two distinct life stages, need specific and strict condition.After terminating the growth period that substrate made by nutritious base; under suitable conditions; produce malicious mould and can produce secondary metabolite; this is without the need to exercising the analytic metabolism function of mould; mostly is one " weapon " as fungi autoprotection; these metabolites may be collected at spore, vegetative hyphae or be directly secreted into also do not gather in the crops or the storage life plant substrates in.Mould generally can form secondary metabolite in sporogenesis before entering next stage, and its generation is more harsher than the condition required for plant growth.The ability of different trichoderma strain generation mycotoxin compound is in quality and quantitatively all can have very big-difference.Even if mould of the same race, belong to different and produce strain system, metabolic capability may be consistent with the speed of growth, but mycotoxin secernment property, secondary metabolite value volume and range of product all can have difference.The biosynthetic diversity of mycotoxin, adds extremely general existence, adds the risk of its mycotoxin contamination.But and the mould of not all produces mycotoxin, only have the special genus of some kinds or strain can secrete relevant toxin, and mould does not mean that on suitable substrate it will produce mycotoxin.Mycotoxin can produce in case not having mould to deposit, i.e. mould dead, but active metabolite also exists.Therefore, and the Aspergillus flavus of not all (Aspergillusflavus) can produce aflatoxin, and only has those strains of carrying aflatoxin gene to produce.If cereal or animal feed are produced malicious mycotic infection, then in this kind of raw material, mycotoxin can become the standard of other mould (fungi) toxin existence.In the feedstuff of the various animal of mycotoxin ubiquity.Most mycotoxin can be present in certain raw material and product always, and because of them, its chemical constitution is all highly stable in process of production.Find at present to produce malicious mould and at least 300 kinds of mycotoxins more than 100 kinds in the feed and food of mycotoxin contamination.And feed (raw material) in mould secretion aflatoxin be study the most sufficient.
The demand of the mankind to aquatic products increases year by year.In addition, cultivated animals is to fish meal, and the consumption of other vegetable raw materials also increases fast.Therefore, feeding quality has become the restraining factors of aquaculture fast development, and the kind of main cultivation is numerous at present, but main still fresh water kind is herbvore and ominivore-fish is main, as grass carp, crucian, carp, Tilapia mossambica etc.Fish meal required for these breed varieties is the byproduct of long tail anchovy (Engraulisencrasicolus), anchovy (Mallotusvillosus) and Manhattan fish (Brevoortiatyrannus), catfish (Clupeaharengus) and sardine fish meal etc. mainly.Even but fish by-product, the method also needing science is reclaimed in its processing, otherwise just may have potential harm, as possibility secondary introducing pathogen or mycotoxin enter in food.AF is considered to the mainly vegetable raw material such as corn and produces between growth and storage life, and fish meal and byproduct thereof are pulverized at it and to be processed or also may be infected in storage process.Because fish meal prices is high, vegetable raw material is trend of the times to the alternative of fish meal.But in aquatic feeds, a large amount of vegetable raw material that uses may make AF infect equivalent risk increase, as can be seen here, selects the vegetable raw material of high-quality to seem most important.Use the feed that infected by AF, by greatly increase the risk of illness outbreak, particularly intensive culture pattern under, the effect of natural bait is almost ignored.The pollution that National crop products probably has 25% to be subject to mycotoxin.FAO investigates display, and the vegetable food raw material of south east asia is very serious by mycotoxin.Asia and African Territories, due to the pollution of mycotoxin, cause great economic loss to the plant husbandry of corn and peanut.The Indian country nutrition committee (ICMR) investigation finds that the situation that the food of India and raw-food material pollute by AFB1 is very severe, and wherein the fish meal sample of 69% is found AFB1 and exceeded standard.Owing to employing some contaminated scrap feed material or irrational pulverizing and storing mode, mycotoxin is caused to grow in intensity in the pollution of aquatic feeds.
Research finds, AFB1 is the virose biologically active noxious material of a kind of tool, AFB1 has genetoxic, carcinogenicity to aquatic livestock, reproductive performance is had to impact, has impact to aquatic livestock immune system, can cause hepatotoxicity wind agitation, carcinogenicity, teratogenesis, mutagenesis and immunosuppressive effect to aquatic livestock and terrestrial animal.So the growth feed of the aquatic livestock of developing a kind of aspergillus flavus resisting toxin B1 can be looked for become the problem demanding prompt solution of those skilled in the art.
Summary of the invention
In order to overcome defect of the prior art, solving the pollution problem of aflatoxin to aquatic feeds, the invention provides the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin.
For solving the problems of the technologies described above, technical scheme provided by the invention is:
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin, its constituent comprises: fennel extract, Pericarpium Zanthoxyli extract, capsicum extract, operculate cleistocalyx bark extract, only dysentery grass essential oil and zeolite powder.
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin, the proportioning of each composition part is: fennel extract 8 ~ 15ml/kg, Pericarpium Zanthoxyli extract 8 ~ 15ml/kg, capsicum extract 10 ~ 18ml/kg, operculate cleistocalyx bark extract 8 ~ 15ml/kg and only dysentery grass essential oil 1 ~ 10ml/kg, zeolite powder 900 ~ 980g/kg.
Further, the proportioning of each composition part is: fennel extract 10ml/kg, Pericarpium Zanthoxyli extract 10ml/kg, capsicum extract 12ml/kg, operculate cleistocalyx bark extract 10ml/kg and only dysentery grass essential oil 5ml/kg, zeolite powder 940g/kg.
Further, formulation can be liquid preparation also can be powder formulation.
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin provided by the invention is used for the aspergillus flavus resisting toxin of aquatic feeds.
Beneficial effect of the present invention is: effectively solve the pollution problem of aflatoxin to aquatic feeds, inhibits the growth of aflatoxin in aquatic feeds and the injury to aquatic livestock.
Detailed description of the invention
Hereafter will describe content of the present invention in conjunction with specific embodiments in detail.It should be noted that the combination of technical characteristic or the technical characteristic described in following embodiment should not be considered to isolated, they can mutually be combined thus be reached better technique effect.
Embodiment 1:
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin, the proportioning of its constituent and composition part is: fennel extract 10ml/kg, Pericarpium Zanthoxyli extract 10ml/kg, capsicum extract 12ml/kg, operculate cleistocalyx bark extract 10ml/kg, only dysentery grass essential oil 5ml/kg and zeolite powder 940g/kg, zeolite powder is as carrier, and formulation is liquid preparation.
Embodiment 2
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin, the proportioning of its constituent and composition part is: fennel extract 8ml/kg, Pericarpium Zanthoxyli extract 8ml/kg, capsicum extract 10ml/kg, operculate cleistocalyx bark extract 8ml/kg, only dysentery grass essential oil 1ml/kg and zeolite powder 900g/kg, zeolite powder is as carrier, and formulation is powder formulation.
Embodiment 3
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin, the proportioning of its constituent and composition part is: fennel extract 15ml/kg, Pericarpium Zanthoxyli extract 15ml/kg, capsicum extract 18ml/kg, operculate cleistocalyx bark extract 15ml/kg, only dysentery grass essential oil 10ml/kg and zeolite powder 980g/kg, zeolite powder is as carrier, and formulation is liquid preparation.
In above-described embodiment 1 ~ 3, the anti-mold effect of the mould inhibitor of the aquatic feeds aspergillus flavus resisting toxin under embodiment 1 proportioning is best.
The mould inhibitor of aquatic feeds aspergillus flavus resisting toxin of the present invention is used for the aspergillus flavus resisting toxin of aquatic feeds.
The present invention effectively solves the pollution problem of aflatoxin to aquatic feeds, inhibits the growth of aflatoxin in aquatic feeds and the injury to aquatic livestock.
Although give some embodiments of the present invention, it will be understood by those of skill in the art that without departing from the spirit of the invention herein, can change embodiment herein.Above-described embodiment is exemplary, should using embodiment herein as the restriction of this interest field.
Claims (5)
1. a mould inhibitor for aquatic feeds aspergillus flavus resisting toxin, is characterized in that, its constituent comprises: fennel extract, Pericarpium Zanthoxyli extract, capsicum extract, operculate cleistocalyx bark extract, only dysentery grass essential oil and zeolite powder.
2. the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin as claimed in claim 1, it is characterized in that, the proportioning of each composition part is: fennel extract 8 ~ 15ml/kg, Pericarpium Zanthoxyli extract 8 ~ 15ml/kg, capsicum extract 10 ~ 18ml/kg, operculate cleistocalyx bark extract 8 ~ 15ml/kg and only dysentery grass essential oil 1 ~ 10ml/kg, zeolite powder 900 ~ 980g/kg.
3. the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin as claimed in claim 1, it is characterized in that, the proportioning of each composition part is: fennel extract 10ml/kg, Pericarpium Zanthoxyli extract 10ml/kg, capsicum extract 12ml/kg, operculate cleistocalyx bark extract 10ml/kg and only dysentery grass essential oil 5ml/kg, zeolite powder 940g/kg.
4. the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin as claimed in claim 1, it is characterized in that, formulation comprises: liquid preparation or powder formulation.
5. a purposes for the mould inhibitor of aquatic feeds aspergillus flavus resisting toxin as claimed in claim 1, is characterized in that, for the aspergillus flavus resisting toxin of aquatic feeds.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510369147.2A CN105028948A (en) | 2015-06-29 | 2015-06-29 | Anti-aflatoxin mould inhibitor for aquatic feeds |
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| CN201510369147.2A CN105028948A (en) | 2015-06-29 | 2015-06-29 | Anti-aflatoxin mould inhibitor for aquatic feeds |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107232478A (en) * | 2017-07-12 | 2017-10-10 | 太仓市荣德生物技术研究所 | A kind of high-performance environment-friendly antibacterial mildew inhibitor |
| CN108094680A (en) * | 2017-12-18 | 2018-06-01 | 广州美瑞泰科生物工程技术有限公司 | A kind of feed detoxifying agent and preparation method and application |
| CN108175027A (en) * | 2017-12-26 | 2018-06-19 | 广州美瑞泰科生物工程技术有限公司 | A kind of Midew preventive for feed and preparation method and application |
| CN109511683A (en) * | 2018-11-16 | 2019-03-26 | 吉林农业科技学院 | A kind of star anise extract and the purposes in prevention and treatment aflatoxin contamination |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1281642A (en) * | 1999-07-27 | 2001-01-31 | 冶金工业部长沙矿冶研究院 | Compound synergistic antioxidant mildew inhibitor for feed |
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2015
- 2015-06-29 CN CN201510369147.2A patent/CN105028948A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1281642A (en) * | 1999-07-27 | 2001-01-31 | 冶金工业部长沙矿冶研究院 | Compound synergistic antioxidant mildew inhibitor for feed |
Non-Patent Citations (1)
| Title |
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| 刘来亭: ""水产饲料中的霉菌及黄曲霉毒素中毒概述"", 《河南水产》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107232478A (en) * | 2017-07-12 | 2017-10-10 | 太仓市荣德生物技术研究所 | A kind of high-performance environment-friendly antibacterial mildew inhibitor |
| CN108094680A (en) * | 2017-12-18 | 2018-06-01 | 广州美瑞泰科生物工程技术有限公司 | A kind of feed detoxifying agent and preparation method and application |
| CN108175027A (en) * | 2017-12-26 | 2018-06-19 | 广州美瑞泰科生物工程技术有限公司 | A kind of Midew preventive for feed and preparation method and application |
| CN109511683A (en) * | 2018-11-16 | 2019-03-26 | 吉林农业科技学院 | A kind of star anise extract and the purposes in prevention and treatment aflatoxin contamination |
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