CN105025805A - Ultrasound imaging of fast-moving structures - Google Patents
Ultrasound imaging of fast-moving structures Download PDFInfo
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- CN105025805A CN105025805A CN201480011463.6A CN201480011463A CN105025805A CN 105025805 A CN105025805 A CN 105025805A CN 201480011463 A CN201480011463 A CN 201480011463A CN 105025805 A CN105025805 A CN 105025805A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/54—Control of the diagnostic device
- A61B8/543—Control of the diagnostic device involving acquisition triggered by a physiological signal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0883—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the heart
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/13—Tomography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
- A61B8/461—Displaying means of special interest
- A61B8/463—Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5207—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5284—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving retrospective matching to a physiological signal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
- G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
- G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
- G01S7/52085—Details related to the ultrasound signal acquisition, e.g. scan sequences
- G01S7/52087—Details related to the ultrasound signal acquisition, e.g. scan sequences using synchronization techniques
Abstract
An ultrasonic diagnostic imaging system is gated to acquire images at different phases of a physiological cycle such as the heartbeat. At each successive heart cycle a trigger actuates the acquisition of a continuous sequence of images, starting at a particular phase of the heart cycle and ending when the next heart cycle begins. Multiple triggers are used, each starting at a different phase of the heart cycle and each acquiring images at uniform temporal spacing. After the first trigger is used a sequence of images has been captured which are temporally evenly spaced over the heart cycle, and as successive triggers are used uniform temporal spacing is maintained as the heart cycle is filled in with additional images for replay of an image loop of phase re-ordered images at a high frame rate of display.
Description
Technical field
The present invention relates to medical diagnostic ultrasound systems, and particularly relate to for rapidly and the moving structure that the such as pulsatile heart of movement is dirty periodically carries out the ultrasonic system of imaging.
Background technology
One in the important use of diagnostic ultrasound imaging is the performance of Diagnosing Cardiac.This is due to the ultrasonic fact that Non-ionizing radiation can be utilized to observe heart beating in real time.Although ultra sonic imaging is relative to fast and can provide real-time (or " fact ") imaging of the structure to fast movement in image frame acquisitions, but usually adopt gate control method to realize image (or frame) rate even faster, to carry out visual to the structure of movement fast better.Gate is the action gathering the image relevant with the specific external physiologic event usually periodically occurred in time.For ultrasonic, this event is usually directed to breath cycle in adult, child and/or Fetal research or cardiac cycle.Usually monitor described event by the external sensor such as the ECG signal of monitoring the relative time in cardiac cycle, but also can monitor described event according to picture material.Utilize the collection of gate, each time on some periodic heart cycles and in cardiac cycle or phase place place can gather cardiac image.After picture frame is collected, according to their relative acquisition times (phase place) in periodic cycle instead of their absolute time (that is, relative to their acquired original sequence), described picture frame is resequenced.Then can with than the higher picture rate that can realize in single cardiac cycle and with reset than the higher display frame rate that can realize in acquired original in other cases through rearrangement picture frame.The example of this collection and rearrangement is illustrated in Fig. 1 of (people's such as Powers) United States Patent (USP) 5099847.This patent illustrates, the first image sequence is collected at odd number cardiac phase place, gathers the second image sequence afterwards at even number cardiac phase place.Fig. 2 of described patent shows by the rearrangement of cardiac phase to image, thus forms the sequence more than the twice reaching image during cardiac cycle.This sequence can be " annular ", that is, be played from start to end, and then from reset, thus be given in the outward appearance of heart beating when being displayed in high frame per second display sequence.Similar method can be used in forming the dirty live three dimensional image of pulsatile heart, described in the United States Patent (USP) 5993390 such as (Savord people).
There are two kinds of methods for performing gate.The method described in the patent of the people such as people and Savord such as Powers is above called as initiatively or perspective gate, in active or perspective gate, and the place's acquisition of image data of preassigned time in cardiac cycle.Such as in the patent of the people such as Powers, be the collection at even phase place before this after odd number phase place place headed by collection is previously designated.The advantage of the method is, image in periodic cycle fully and collected equably.But, the exemplary shortcomings of the method is, frame per second through rearrangement must be previously designated, thus accurately specify when should gather image relative to gated events, the persistent period of ECG signal and cardiac cycle will change and even will change between different time for same patient between different patient.Another shortcoming is, the method can take a long time to gather all required data, because substantial delay may need to be inserted in collection to guarantee that the time of all expectations in periodic cycle is sampled.
Another gate control method is called as retrospective gated.In this approach, in the pattern being commonly called real-time or " fact " pattern, (namely many continuous physiological periods gather continuously, when completing the collection of piece image, the collection of another width is started immediately) image, and do not consider the relative time in periodic cycle.But, adopting the time of Centralizing inspection relative to the collection to every width image of external event, making just to resequence to image once complete to gather.The modification being called as this technology of " STIC " (space-time image correlation) is generally used for the high frame rate image sequence collecting heart of fetus.For example, see " Spatio-temporalimage correlation (STIC): new technology for evaluation of the fetal hear " (Ultrasound Obstet.Gynecol. of the people such as G.R.Devore, 22nd volume, 380-87 page (2003)).The advantage of the method is, image is collected (that is, not postponing) between images as far as possible rapidly, and when more periodic cycle is observed, the potential frame per second through rearrangement becomes higher.But the shortcoming of the method is, do not ensure that the image through rearrangement will be sampled fully or equably to interested periodic cycle.
Summary of the invention
According to principle of the present invention, a kind of ultrasonic diagnosis imaging system is provided for and gathers the image relevant with periodic cycle, makes it possible to the real-time image sequences of the image showing non-uniform time interval.When described be captured in multiple periodic cycle continues time, the display sequence of evenly spaced image can be produced always, wherein, when gathering continuation, the interval of evenly spaced image becomes further meticulous, thus makes it possible to the image cycle of playback to the display frame rate constantly increased.This can by using different trigger collection to realize, and described different trigger collection is used to make the delay minimization between the acquisition sequence triggered in the most efficient manner.
Accompanying drawing explanation
In the accompanying drawings:
Fig. 1 illustrates the ultrasonic diagnosis imaging system according to principles of construction of the present invention in block diagram form.
Fig. 2 illustrates the acquisition sequence using the perspective gate relevant with ECG signal.
Fig. 3 illustrates the acquisition sequence using the retrospective gated relevant with ECG signal.
Fig. 4 illustrate use four trigger collection according to acquisition sequence of the present invention.
That Fig. 5 illustrates use four trigger collection and diagram is for showing the acquisition sequence of the present invention of availability of the image cycle of the time frame per second of the continuous increase of evenly spaced image.
Detailed description of the invention
First with reference to figure 1, the ultrasonic system according to principles of construction of the present invention is shown in block diagram form.Illustrated ultrasonic system is operated by two major subsystems, and described two major subsystems are front-end collection subsystem 10A and display subsystem 10B.Ultrasonic probe is coupled to acquisition subsystem to launch ultrasound wave and to receive ultrasound echo signal.Described probe can utilize linear (one dimension) row of element of transducer to carry out this point, or can use the two-dimensional matrix array 70 of element of transducer.2D matrix array and, if desired, 1D array operates by being positioned in the microbeamformer 72 had in the probe of array energy transducer.Microbeamformer comprises circuit, and the signal that described control circui is applied to the group of the element of array energy transducer 70 gathers with the echo-signal received the element by each group and carries out some process to described echo-signal.Microbeamformer in probe advantageously reduces the quantity of the conductor in the cable between probe and ultrasonic system, and be described in the United States Patent (USP) 5997479 such as (Savord people) and (Pesque's) United States Patent (USP) 6436048, and on launching and provide the electronic control of wave beam at wave beam reception period and focus on to carry out (fact) imaging in real time of high frame per second.
Probe 70,72 is coupled to the acquisition subsystem 10A of ultrasonic system.Acquisition subsystem comprises beamform controller 74, the control of described beamform controller to control panel 40 is made response and control signal is provided to microbeamformer 72, thus about to send and probe is instructed in the timing of received beam, frequency, direction and focusing.According to principle of the present invention, control signal also comprises the trigger collection for gathering image in the fixed time (phase place) relevant with physiology gate-control signal.Beamform controller is also controlled by the Wave beam forming of acquisition subsystem to the echo-signal received by its control to modulus (A/D) transducer 18 and Beam-former 20.Amplified by the preamplifier in acquisition subsystem and TGC (time gain control) circuit 16 by the echo-signal of the part Wave beam forming received of popping one's head in, then carry out digitized by A/D converter 18.By main system Beam-former 20 by be formed as handling completely through digitized echo-signal and focus on wave beam.Echo-signal is processed by image processor 22, the filtering of described image processor combine digital, B-mode and M-mode detect and doppler processing, and other signal processing can be performed, such as harmonic wave separation, speckle minimizing and other picture signal process expected.
The echo-signal produced by acquisition subsystem 10A is coupled to display subsystem 10B, and described display subsystem process echo-signal is presented on display screen 62 for the picture format expected.Echo-signal is processed by image line processor 24, described image line processor can be sampled to echo-signal, the fragment assembly of wave beam is become complete line signal and to line signal be averaged for signal to noise ratio improve or stream persistence.Image line for 2D (two dimension) image be by scan converter 26 scan conversion be expect picture format, described scan converter performs R-theta as known in the art and changes.Scan converter is therefore, it is possible to format straight line or sector image format.Then described 2D image is stored in image storage 28 together with other 2D images, and described image can be displayed on display 62 from described memorizer.Image in memorizer also with the Graphics overlay that will be shown together with image, described figure generated by graphic generator 34, described graphic generator to user control 40 make response make produce figure be associated with the image of display.Individual images or image sequence can be stored in image storage 28 for display image cycle or live sequence.Diagnostic image can be stored in the image storage 128 of networking.
For real-time volume imaging, display subsystem 10B also comprises 3D (three-dimensional) image rendering processor 32, and described 3D rendering rendering processor receives image line from image line processor 24 for drafting real time 3-D image.3D rendering can be shown as fact (in real time) 3D rendering or be coupled to for storing 3D data set for the image storage 128 checked and diagnose after a while on display 62.According to principle of the present invention, provide image rearrangement processor 30, the order that the image collected according to the present invention will be shown determined by described image rearrangement processor.Described image rearrangement processor can by having carried out this point with suitable order by the image collected storage in the image processor, described image is displayed in the sequence that described image is stored in wherein according to described order suitably, or described image rearrangement processor can complete this point by utilizing the data describing the order be shown together with image that every width image will collect with other to carry out mark to described image.
ECG subsystem is provided for and uses when the particular phases place being desirably in cardiac cycle gathers image.ECG wire 50 can be attached to patient with bonding mode and provide ECG signal to QRS processor 52, the R crest of each heart beating of described QRS processor identification.To the timing of R ripple for gathering the image of specific cardiac cycle.Can by the timing of R ripple being coupled to beamform controller 74 as the triggering signal from triggering signal maker 54 and carrying out to gather at the particular phases place of cardiac cycle the image of heart to the control of control panel 40, the described control to control panel 40 is used for the cardiac phase by selecting suitable trigger collection to select to gather at its place the expectation of the image of cardiac phase gate, as described below.
As described earlier, the problem run in physiology gate is, when use in conventional prospective gating technology or retrospective gated technology any one time, need to specify the desired frame per second (perspective gate) through rearrangement in advance, comprise large delay (perspective gate) in collection, or abundant (completely) and the uniform sampling (retrospective gated) of periodic cycle can not be guaranteed.User is undesirably made to specify frame per second through rearrangement in advance, because user can determine between Harvest time or afterwards to need the frame per second higher than original frame per second of specifying.In this case, user must perform another collection to image with new preassigned frame per second.On the contrary, expect when gather advance time make imaging system automatically with the frame per second increased gradually of evenly spaced image to gather image.In addition, delay large between Harvest time is less desirable, because longer acquisition time increases the probability of patient moving or probe movement, described patient moving or probe movement can cause acquisition sequence unavailable.In addition, the time is valuable in clinical setting, and large delay is converted into and can be spent in gathering time of other view data in other cases.Equally, in order to afterwards to image rearrangement only with between Harvest time or find afterwards to interested periodic cycle fully and the not obtained intention of uniform sampling and to gather image be unacceptable.
Can by understanding these problems more fully with reference to the perspective gate sequence of figure 2 and the retrospective gated sequence of Fig. 3 respectively.It is the ECG waveform 60 that the QRS ripple 62 periodically repeated is shown in the bottom of Fig. 2.The peak of QRS ripple is used as the time reference for each new cardiac cycle.Be the row of the round dot of six evenly spaced times of labelling on ECG waveform, be desirably in described six evenly spaced time durations and gather ultrasonoscopy.Ultrasonoscopy is gathered to generate from the echo-signal returned along every bar scanning line by the sequence sending spatially adjacent scanning line.The quantity of the scanning line needed for 2D image is 128 adjacent scanning lines normally, and described 128 adjacent scanning lines are processed to produce 2D image by scan converter 26.Usually 3D rendering is produced according to thousands of scan lines, the volumetric region of described thousands of scan lines scanning health.Each rectangle 42 on the row of round dot ... 58 instructions are sent out for the scanning line of piece image and echo received time during it.The beginning to image acquisition is taken as in this example for the time reference of every width image.The phase place collected for its image in six phase places of dimmed round dot labelling heart beating.Can see, the first round dot in row is dimmed with the collection of labelling to the first image 42.After this image is collected, there is cycle idle time, during described cycle idle time, do not have collection to carry out, until the time of the 4th round dot of the first cardiac cycle, locate in the described time, the second image 44 is collected.Then, there is another cycle idle time, until second phase place the 3rd image in cardiac cycle during the second cardiac cycle is collected.Illustrate at this phase place place image of heart beating collected at the dimmed round dot of the beginning of the second cardiac cycle, described image is the first image 42.After the 3rd image 46 is collected, there is another idle time interval, until the 4th image 48 is collected at the 5th phase place place of the second cardiac cycle.This image acquisition interval extends to the beginning of the 3rd cardiac cycle, after this, there is another idle time interval, until collected at third phase place the 5th image 56 of the 3rd cardiac cycle.After the collection to the 5th image, there is another idle time interval, until collected at the 6th phase place place the 6th image 58 of the 3rd cardiac cycle.Complete place in the collection to the 6th image 58, can see, six width images are collected at six evenly spaced phase place places of heart beating, but spent three cardiac cycle to gather all six width images.This six width image is reordered for showing with annular and being reset with cardiac phase order, and described cardiac phase order is image 42,46,56,44,48 and 58.To reset this six width image with this reiteration, thus illustrate that the pulsatile heart of movement is dirty in real time with the cardiac phase of six width time evenly spaced images order.But can see, cause a large amount of idle time, not have image collected during described idle time, thus increase the probability gathered being subject to probe movement or patient moving interference, this will require again to perform collection.
In figure 3, in extremely rapid succession, one followed by another ground acquired image frames.Cardiac cycle persistent period illustrated in utilization and the time gathered required for every width image, can see, during the first cardiac cycle, collect three width images.But described timing makes after the picture frame gathered during the second cardiac cycle tightly drops on the time of the first image set, and in this example, this second image set 48,56 and 58 falls behind in 1/18th of the cardiac cycle after the first collection.The relevant collection of this phase place proceeds the 3rd cardiac cycle, as shown in the accompanying drawings.Until perform collection in six cardiac cycle, just with the complete set of the evenly spaced incremental crawler of cardiac cycle to 18 width images.After the first cardiac cycle, other five cardiac cycle must be waited for, until collected time evenly spaced image set.
The present invention is improved these situations by the combination of the design of perspective gate and retrospective gated.Creative drainage pattern is designed such that any time place between Harvest time always exists the collection of frame, and the collection of described frame is spaced apart equably on periodic heart cycles.When more periodic cycle is observed, time migration between the frame of rearrangement is implemented as and makes to offset between all frames through resequencing is almost uniform, and be implemented as and make skew become more and more less, thus obtain the more and more higher frame per second through rearrangement for showing.This allow user with expect the same less or as many cycle period gather, and always can carry out rearrangement to frame afterwards and make periodic cycle fully and be sampled equably.Because creative method requires only little delay, so drainage pattern operates in close in real-time mode or live mode, thus allow described pattern for all real-time or live imagings, but the sequence with any collection can be re-ordered into the advantage of the higher frame per second sequence in single periodic cycle.
The basic guiding principles of drainage pattern of the present invention are as follows:
A, gather image and make locating if having time between Harvest time, cyclical signal fully (or fully) and be sampled equably.
B, collection image, make when the periodic cycle of larger quantity is sampled, the time migration between the frame through rearrangement becomes less, thus obtains the higher frame per second through rearrangement.
C, gather image in continuous print mode as far as possible, wherein, almost do not postpone between images in collection or do not postpone.
D, between Harvest time, provide the display of the potential frame per second through rearrangement of instruction to user.The example of display will be the display with the unit of time numeral (Hz) of the potential frame per second through rearrangement of instruction and/or draw (bar, line, pie chart etc.) and/or color (such as, wherein blueness is low frame per second and redness is the colour scale of high frame per second).Described display also can individually or take the frame by illustrating closest to the previous collection of the real-time time position relative to periodic cycle that the form of the frame through rearrangement is shown in real time except previously mentioned display packing.By this way, when more circulation is sampled and more frame is collected, this to show as in scheduling real-time periodic cycle period become more and more level and smooth effect by having picture material, thus provides the qualitative evaluation to the frame per second through rearrangement.
In the embodiment of structure, triggered by one group or interrupt controlling drainage pattern.The feature triggered is during each periodic cycle, occur that the regular time from time boundary mark offsets.With only use in regular time skew place relative to the R crest in ECG signal single triggering conventional gate collection compared with, multiple triggerings that this embodiment of the present invention uses its time migration to change in whole collection.Trigger instruction when can start the collection of the free-running operation of the frame of limited quantity in given periodic cycle.These triggerings are assigned with in groups, and wherein, the size of group is fixing for the length gathered.Only be reallocated after each triggering from group is by use for the time migration triggered.In any given periodic cycle, when the relative time offset place apart from periodicity time boundary mark being captured in this certain trigger of the free-running operation of frame starts, trigger and be regarded as by " use ".The time migration triggered is reallocated, and make any given time place between Harvest time, the interval of the frame collected obtained obtains the sampling adequately and uniformly in cardiac cycle.Such as in simple example, this can have been come by the center time point of the trigger offset time migration of triggering being assigned as all previous uses.
Example illustration is below using the R peak in ECG signal to this triggerings distribution under the background of the gate of ultrasound frames and is redistributing strategy.This example is the example that use four triggers, but can by expecting the triggering using less triggering or more.Although should also be noted that and employ ECG signal and R crest in this example, any cyclical signal and periodicity time boundary mark can be used in other places.
In this example, the collection for being enabled in the free-running operation during single cardiac cycle is triggered.After the triggering utilized, frame is collected continuously, until another R crest is observed.After the last picture frame from previous loops is collected, next available triggering is selected.Correspondingly, all triggerings appear at after R crest between a frame acquisition zone d
fin, wherein, be the length of the time gathering the cost of single frame between frame acquisition zone.Trigger also to be implemented as and open about equally spaced between the frame acquisition zone after R crest.In the example of Fig. 4, four illustrated triggerings are at d
fthe upper equally spaced time 0 ﹒ d opened between acquisition zone
f/ 4, d
f/ 4,2d
f/ 4 and 3d
f/ 4 places start.Equal intervals guarantees that the energy collecting of the frame collected during any given time is in the length of collection is reordered enough in the following manner: will obtain the interval adequately and uniformly in cardiac cycle.
The diagram of the distribution of this initial trigger and the frame collection subsequently in some circulations is illustrated in the diagram.In this example, employ four triggerings, described four triggerings are marked as T1, T2, T3 and T4.Described four are triggered d between frame acquisition zone
fdifferent evenly spaced phase place places start.In the diagram, d between frame acquisition zone
findicated by dotted line frame 74.These trigger four the evenly spaced phase places started at its place and appear at time t=0,1,2 and 3 by the circle mark on the right side of each ECG waveform 60.
During the first cardiac cycle, circulation 1, trigger T1 and used, trigger T1 and gather four width images immediately continuously, as indicated by the time bar 82 below circulation 1ECG waveform.The time place being captured in the R crest 62 of circulation 1 of the first picture frame is started.The end of time articles 82 illustrate by this triggering to the 4th frame be captured in the time interval of the beginning of circulation 2 during terminate.This end time is shown in the d on the right side of circulation 2 waveform
ftime t on timeline
stoparrow 92.Due to t
stoponly trigger T3 beginning before occur, so T3 be used as next trigger, thus provide trigger T1 end and trigger T3 beginning between almost do not postpone.Trigger T3 then during circulation 2 for gathering three picture frames, as shown by the time bar 84 below circulation 2 waveform.Be regarded as only occurring after the beginning of circulation 3 to the completing of collection of last picture frame of triggering T3, as by t
stopindicated by labelling 94.At t
stopnext available untapped triggering is afterwards the collection that T2, T2 are used for during circulation 3.As illustrated in time bar 86, this triggering collection four successive image frames, last in described four successive image frames completes during the part after a while in the df interval of the beginning of circulation 4, as by t
stoplabelling 96 labellings.Due to this t
stoptime only in the end occurs, so this triggering is for gathering last four evenly spaced picture frames of described acquisition sequence, as indicated by time bar 88 before untapped triggering T4.Therefore this acquisition sequence utilizes the minimum idle time between the end and next untapped triggering of the continuous acquisition of each triggering to gather 15 time evenly spaced picture frames of cardiac cycle.
Trigger be reallocated the quantity making to trigger keep identical, trigger between relative time keep the constant and new trigger offset time to divide maximum interval in time equally, as what see between any in the skew that previously used between Harvest time.This diagram is illustrated in Figure 5 for which using four situations about triggering.Because each triggering is the starting point of the collection of free-running operation, so conclude that the relative frame sequence for the frame in cardiac cycle will be spaced apart with being similar to the described triggering time started, and therefore, only at t=0 (R crest) and t=d
f(R crest+d
f) between time frame be illustrated.Illustrate that the triggering T1 in triggering group 1 line is regarded as sampling to the cardiac cycle in four evenly spaced times by the circle mark of four on the time line.Triggering T2 utilizes the other four width images at evenly spaced four some places in time between the time of T1 collection to sample to cardiac cycle, shown by the bright circle by the T2 carrying out sampling in triggering group 2.In triggering group 3a, trigger T3 and cardiac cycle is sampled, as indicated by bright circle.After these images are collected, can see, cardiac cycle is not be sampled equably in time, because there is gap between each group of three picture frames.Will stop at this some place if gathered, then T1 gathers the result that the result of (triggering group 1) or T1+T2 gather (triggering group 2) and will be used for annular display because in these both obtain in the time gathers uniformly.In triggering group 3b, trigger by utilizing the gap that T4 acquired image frames fills triggering group 3a.Again, the uniform sampling of cardiac cycle is presented, specifically with than previously higher display frame rate.At triggering group 4a, 4b and 4c place, cardiac cycle is sampled by triggering T5, T6 and T7.This increases Time Density to the sampling of cardiac cycle, but can see, after any in the collection that these trigger, it is uneven for sampling in cardiac cycle.Will stop between to any Harvest time in these groups if gathered, then the result of triggering group 3b will be used for the time and show uniformly.But when by utilizing as sampled to cardiac cycle in the collection of the triggering T8 shown in triggering group 4d, can see, time samples uniformly and is again stored, specifically with than frame per second (32 picture frames in cardiac cycle) even higher before.Can see, any time of gatherer process after first triggers can be interrupted, and still provides the image sequence of the time uniform sampling to cardiac cycle to user.
Therefore, it is possible to see, owing to employing the triggering of fixed qty, so there is the example even to the Non uniform sampling of cardiac cycle after all triggerings from group are by use during gatherer process.This is observed in triggering group 3a, 4a, 4b and 4c.But, there is the potential subset of the frame that wherein uniform sampling is observed in any given time place after first triggers.Such as, end at triggering group 3a place if gathered, then the collection of the frame collected in all triggering groups before this group is sampled uniformly.Similarly, end to organize 4a, 4b or 4c place if gathered, then from group 3b with before all triggering groups in the collection of all frames that collects be sampled uniformly.
In embodiments of the present invention, between Harvest time, the triggering be not also used in group can be there is, but the deadline of frame owing to collecting in previous loops, do not have triggering to be reached, because for all n, t
stop> t
trigger, n, wherein, t
trigger, nit is the relativity shift triggering n.These untapped triggerings are called as " can not reach ".Such as, if the t in circulation 4
stopoccurred after last triggering instead of only, then occur in this example shown in Figure 4, thus last triggering T4 is unreachable in circulation 4.There are some modes of this situation of process.First option waited for complete cardiac cycle before any other frame of collection.When doing like this, when next R crest is observed, frame collection can start in any triggering place, because do not have frame to be previously collected in current cardiac cycle period.The delay of a cardiac cycle is inserted in collection by this option, and this can prove too large delay.Another option dynamically changes the triggering still needed by using, and makes them appear at time t
trigger, n+ d
fplace.This is by d between a frame acquisition zone
fbe increased to the equivalence of current untapped triggering.When doing like this, any in available triggering should be used.Owing to not terminating just to be implemented by the triggering used after this change, their shift time is changed the shift time be previously assigned with getting back to them.The shortcoming of this flow process is, compared to original trigger offset, it causes in other cases to by for terminating just by collected the first frame of the certain trigger used " skipping ".Use the experiment of variable frame rate and the quantity of the triggering of actual patient ECG signal has been illustrated that this incidence rate is very little.Another option processing this situation takes measures to prevent it from occurring.A kind of mode reaching this point uses (according to previous loops realization) to be limited in the quantity of the frame collected in previous cardiac circulation to the estimation of cardiac cycle time and acquisition frame rate by being.If estimate that last frame will end to make all untapped triggerings inaccessiable time in next circulation locate, then the time place that the quantity of the frame collected in previous loops is controlled to will triggering be enable to reach stops acquisition frame.Again, experiment has illustrated that this incidence rate is very little.
Person of skill in the art will appreciate that, design of the present invention can be used with different variants and modifications.Such as, can allow to trigger the place of any time during residing on periodic cycle, instead of limited window place, described in previous cases.Multiple signal and/or multiple time boundary mark can be used to perform gate.The triggering of variable number can be used in collection, or variable trigger interval can be employed in collection.Stop frame collection immediately can be observed (such as, R crest) in time boundary mark after, although this obtains only partial frame collection, do not become preventing and can not reach by the triggering used.Trigger also can between Harvest time any time place instead of the triggering only in group all by use time be dynamically allocated.Those skilled in the art easily will carry out other modification.
Claims (15)
1. a ultrasonic diagnosis imaging system, it can operate for gathering ultrasonic image frame, and described ultrasonic image frame is spaced apart equably in time during periodic cycle, and described ultrasonic diagnosis imaging system comprises:
For the source of the physiology gate-control signal of periodic cycle;
Acquiring ultrasound image subsystem, it makes response to described gate-control signal, and described acquiring ultrasound image subsystem is suitable for gathering ultrasonoscopy at the predetermined phase place of described periodic cycle;
Image processor, it processes the ultrasonoscopy collected;
Image sequencer, it prepares for being presented at the image in relative phase sequence;
Display, it makes response to described image processor and described image sequencer, and described display is presented at the live sequence of the image in periodic cycle; And
Trigger source, the continuous sequence of the image it is combined to make described image acquisition subsystem be captured in periodic cycle with described gate-control signal during, described in be captured in described periodic cycle predetermined phase place start.
2. ultrasonic diagnosis imaging system according to claim 1, wherein, described trigger source also comprises: the first image acquisition triggers, and it starts image acquisition at the first phase place of described periodic cycle; And second image acquisition trigger, it starts image acquisition at the second phase place of periodic cycle.
3. ultrasonic diagnosis imaging system according to claim 2, wherein, described second image acquisition triggers and starts image acquisition at second phase place, the described second phase time is the halfway between the collection to the first image by described first image acquisition triggering and the collection to the second image.
4. ultrasonic diagnosis imaging system according to claim 3, wherein, described trigger source also comprises the 3rd image acquisition to be triggered, described 3rd image acquisition triggers and starts image acquisition at the third phase place of described periodic cycle, wherein, the described third phase time is the collection to image triggered by described first image acquisition and triggered by described second image acquisition to the halfway between the collection of image.
5. ultrasonic diagnosis imaging system according to claim 3, wherein, when triggering the finishing of image acquisition at the phase place place of cyclical signal by described first, next triggering of use is the triggering that the beginning phase place place occurred at the next one of untapped triggering starts.
6. ultrasonic diagnosis imaging system according to claim 3, wherein, the feature of described triggering is also: after the use triggered described first, can obtain the sequence of the image collected, described in the image that collects be spaced apart equably in time in periodic cycle.
7. ultrasonic diagnosis imaging system according to claim 6, wherein, the feature of described triggering is also: after the use to the triggering in succession after described first triggering, the sequence of the image collected can be obtained, described in the image that collects be spaced apart equably in time and than by described first triggering collection to the sequence of described image be spaced apart more closely in time.
8. ultrasonic diagnosis imaging system according to claim 1, wherein, triggers any other image being suitable for not gathering after the gate-control signal of next periodic cycle in succession in the described continuous sequence of described image.
9. ultrasonic diagnosis imaging system according to claim 1, wherein, described periodic cycle also comprises cardiac cycle, and wherein, the source of described gate-control signal also comprises ECG electrode.
10. ultrasonic diagnosis imaging system according to claim 1, wherein, described periodic cycle also comprises breath cycle.
11. ultrasonic diagnosis imaging systems according to claim 1, wherein, described display is also suitable for the live sequence being presented at the image in periodic cycle, and is suitable for the described live sequence of the described image of playback continuously from start to end, until stop.
12. ultrasonic diagnosis imaging systems according to claim 1, wherein, the described live sequence shown by described display also comprises the sequence of the image collected sorted by described image sequencer,
Wherein, described display also shows the frame per second of the described live sequence sorted by described image sequencer.
13. ultrasonic diagnosis imaging systems according to claim 12, wherein, described frame per second numerically, to graphically or by color shows.
14. ultrasonic diagnosis imaging systems according to claim 1, wherein, start acquisition sequence in the frame acquisition zone of all triggerings in described triggering after physiology gate-control signal.
15. ultrasonic diagnosis imaging systems according to claim 14, wherein, the evenly spaced interval place of all triggerings in described triggering between frame acquisition zone starts acquisition sequence.
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| US201361771979P | 2013-03-04 | 2013-03-04 | |
| US61/771,979 | 2013-03-04 | ||
| PCT/IB2014/058694 WO2014135996A1 (en) | 2013-03-04 | 2014-01-31 | Ultrasound imaging of fast-moving structures. |
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| GB2519745B (en) * | 2013-10-22 | 2018-04-18 | Canon Kk | Method of processing disordered frame portion data units |
| EP3200450A4 (en) * | 2014-09-26 | 2018-05-30 | Olympus Corporation | Transmission system and processing device |
| CN104546003B (en) * | 2015-01-27 | 2017-02-01 | 哈尔滨工业大学 | VFR (variable frame rate) color ultra-high speed ultrasonic imaging method based on plane wave transmission |
| KR102182489B1 (en) * | 2016-07-26 | 2020-11-24 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | Method of generating ultrasound image, ultrasound system and storage medium |
| DE112019003225T5 (en) * | 2018-06-28 | 2021-03-11 | Murakami Corporation | Heartbeat detection device, heartbeat detection method and program |
| JP7242621B2 (en) * | 2020-10-27 | 2023-03-20 | ジーイー・プレシジョン・ヘルスケア・エルエルシー | Ultrasound image display system and its control program |
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| Publication number | Publication date |
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| EP2964098B1 (en) | 2020-09-30 |
| US10736611B2 (en) | 2020-08-11 |
| JP2016508809A (en) | 2016-03-24 |
| CN105025805B (en) | 2018-04-13 |
| US20160015367A1 (en) | 2016-01-21 |
| EP2964098A1 (en) | 2016-01-13 |
| WO2014135996A1 (en) | 2014-09-12 |
| JP6486839B2 (en) | 2019-03-20 |
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