CN105021634A - Rapid microwave moisture measurement method for fluid extract and extract - Google Patents
Rapid microwave moisture measurement method for fluid extract and extract Download PDFInfo
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Abstract
The invention relates to a rapid microwave moisture measurement method for a fluid extract and an extract. The method comprises the following steps: 1, taking two pieces of glass fiber papers, putting the glass fiber papers on a balance of a microwave moisture measurement apparatus and weighing in a peeling manner, taking an extract sample and putting the extract sample on one piece of glass fiber paper, covering with the other piece of glass fiber paper and flattening, then putting the papers back to the balance, covering with a detection pool, beginning to detect and recording a measurement value; 2, substituting the measurement value of the microwave moisture measurement apparatus into a data model, and calculating the moisture value according to the formula that the moisture value of the extract is equal to X * the measurement value of the microwave moisture measurement apparatus + Y, wherein X and Y are relationship parameters of moisture measurement by microwaves and moisture measurement by a drying method.
Description
Technical field:
The present invention relates to a kind of determination of moisture method in Chinese medical concrete, particularly a kind of rapid microwave determination of moisture method of liquid extract and extract.
Background technology:
Form of Chinese drug roughly divides three classes at present: i.e. extract, medicinal extract+crude drug powder agent and crude drug powder preparation.The full medicinal extract preparation of Chinese medicine is the principal mode of modern Chinese herbal medicine preparation, and this preparation both can guarantee effective constituent all in decoction, met again the requirement of solid preparation of traditional Chinese medicine, therefore is a kind of common formulations.And through the full medicinal extract solid pharmaceutical preparation of Chinese medicine that extraction and isolation is made, all there is moisture absorption in various degree, deliquescing after causing the Chinese medicine preparation moisture absorption, appearance color deepen, lump, mobility reduces, even goes mouldy, thus affect quality and the curative effect of medicine, bring difficulty to production and storage.
Another problem of the full medicinal extract preparation of Chinese medicine is the moisture control of medicinal extract before feeding intake, if medicinal extract water cut is too high, wetting agent will produce stronger viscosity a little, makes pelletization very difficult.Range of control required for different medicinal extract is different, will determine according to the actual conditions of preparation.Medicinal extract is divided into liquid extract and dry extract, Chinese medical extract is concentrated to certain concentration, moisture is not all removed, the medicinal extract still with liquid substance sample mobility is called liquid extract, and Chinese medical extract moisture major part is removed, the medicinal extract with solid features is called dry extract, actually no matter be or that liquid extract dry extract moisture is wherein how many, also need further mensuration, traditional determination of moisture method is as chemical reagent titrimetry, heating, drying weight method, the laboratory technique such as conductance method and capacitance method not only sampling routine is consuming time loaded down with trivial details, and do not reach contactless, the requirement of the online water content detection of industry.
Microwave water content detection method is widely used, novel detection method at present.Microwave aquametry is that hydrone produces various polarization phenomena and dielectric relaxation phenomenon under the effect of microwave, and macro manifestations is the change of the related physical quantity of the specific inductive capacity such as resonance frequency, power, phase place of microwave signal.Microwave moisture detecting method utilizes the method measuring material specific inductive capacity to carry out indirect detection material moisture based on above-mentioned mechanism.Microwave moisture detecting method not only has the advantage of electro-detection, also has the following advantages: one, and detection efficiency is high, be convenient to real-time processing controls and detection of dynamic; Two, highly sensitive, less to the susceptibility of environment; Three, low to the susceptibility of temperature, color, salinity material and grain size.The moisture that the method detects is full water, i.e. surface water and internal water.Near infrared spectroscopy can only detect certain thickness material to be measured, belongs to surface measurements technology, is difficult to the volume moisture reflecting whole material, and in addition, test substance impurities also has the impact such as scattering and absorption to infrared ray.Therefore, microwave moisture content assay method is more more accurate than surface detection technique such as near infrared spectroscopies, belongs to depth detection technology.This technology utilizes microwave energy, can not heating volatile composition (as: oil, fat, essence and flavoring agent etc.), only act on dipole molecule (hydrone and some organic solvents CCl4 etc.), radiation-permeable sample heats in sample interior, microwave frequency between 2.4 ~ 2.5GHZ only works to hydrone, and determination of moisture is accurate.
Liquid extract and extract take oven drying method carry out water content detection or measure loss on drying, detect length consuming time---and do not comprise the time of constant weight measuring cup, namely sample drying needs more than 8hr to constant weight.
The present invention on the basis of existing technology, introduce near infrared, in the modeling theory of the detection technique such as infrared, by multiple batches of sample determination of moisture, set up the model of microwave moisture content determination method and traditional oven drying method, then, accumulation production data, carries out external certificate to data model.Set up a kind of rapid microwave determination of moisture method of liquid extract and extract.
Summary of the invention:
The invention provides a kind of rapid microwave determination of moisture method of extract, said method comprising the steps of:
Step 1, gets medicinal extract microwave moisture meter and detects moisture, record measured value;
Step 2, substitutes into the actual water score value in following data model calculating medicinal extract: the measured value+Y of medicinal extract moisture value=X × microwave moisture meter by the measured value of microwave moisture meter.
Wherein, X, Y are the Relation Parameters of microwave determination of moisture and moisture analysis.
Preferred method of the present invention, comprises the following steps:
Step 1, gets two all-glass papers, the balance being placed in microwave moisture meter is removed the peel and weighs, get medicinal extract sample, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, starts to detect, record measured value.
Step 2, substitutes into following data model and calculates moisture value: the measured value+Y of medicinal extract moisture value=X × microwave moisture meter by the measured value of microwave moisture meter.
Wherein, X, Y are the Relation Parameters of microwave determination of moisture and moisture analysis, and for the medicinal extract of separate sources, its numerical value is different, as following parameter:
Blood-nourishing and brain-refreshing the water extracted immersing paste moisture value=0.4884* microwave moisture measured value+15.465
Blood-nourishing and brain-refreshing alcohol-extracted extract moisture value=0.488* actual microwave moisture measured value+15.367
Root of herbaceous peony medicinal extract moisture value=0.6926* actual microwave moisture measured value+10.23
The preparation method of parameter X, Y is as follows:
Chinese medical concrete microwave moisture measured value and oven drying method (existing) determination of moisture value are strong positive correlation, according to related datas such as slopes, obtain
x, Ycorrelation values, and then obtain following formula: the measured value+Y of medicinal extract moisture value=X × microwave moisture meter.
Wherein preferably the assay method of microwave moisture meter is as follows:
Setting microwave moisture meter parameter
After setting parameter, get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, record measured value.
Wherein oven drying method determination of moisture method can be adopted with the following method:
Get test sample 2 ~ 5g, be laid in and be dried in the flat measuring cup of weight, thickness is no more than 5mm, accurately weighed, open bottle cap 100 ~ 105 DEG C of dryings 5 hours, bottle cap is built, in dislocation exsiccator, cool 30 minutes, accurately weighed, then said temperature drying 1 hour, cooling, weigh, to double difference of weighing is no more than 5mg.According to the weight of less loss, calculate water cut (%) in test sample.
Relational language is explained
Dielectric relaxation: dipole moment is the potential energy of the polar molecule of μ in homogeneous mass system E.When adding external electric field, dipole moment will turn to the direction of field parallel to reduce potential energy, and thermal motion makes the balanced orientation of molecule obey Bridgman distribution.When cancelling external electric field, medium molecule will return to the disorderly state of orientation that average dipole moment is zero, and this process needs certain hour just can complete due to the inertia of molecule itself and the glutinousness of medium, is called dielectric relaxation.
Specific inductive capacity: medium can produce induced charge when extra electric field and weaken electric field, former extra electric field (in vacuum) is relative dielectric constant (permittivity), also known as permitivity, with frequency dependence with the ratio of electric field in medium.Specific inductive capacity is absolute dielectric constant product in relative dielectric constant and vacuum.
Quan Shui: surface water and internal water sum.Surface water, the moisture lost when reaching balance under certain condition with ambient air humidity; Internal water, the moisture kept when reaching balance under certain condition with ambient air humidity.
Medicinal extract: refer to the suitable solvent extraction of medicine materical crude slice, boil off part or all of solvent, be adjusted to normal concentration and form.
Blood-nourishing and brain-refreshing the water extracted immersing paste: prepared rhizome of rehmannia, reticulate millettia, selfheal, yncaria stem with hooks, the root of Chinese wild ginger, mother-of-pearl extracting in water, concentrated, alcohol precipitation, is separated clear liquid, reclaims ethanol, continues to be concentrated into thick paste.
Blood-nourishing and brain-refreshing alcohol-extracted extract: Radix Angelicae Sinensis, Ligusticum wallichii, cassia seed, corydalis tuber add rare alcohol reflux and extract, and extract reclaims ethanol, continues to be concentrated into thick paste.
Root of herbaceous peony medicinal extract: the root of herbaceous peony adds rare alcohol reflux and extracts, and extract reclaims ethanol, continues to be concentrated into thick paste.
Be below the method for building up of determination of moisture method of the present invention:
1) microwave method and the sample of traditional furnace drying method to the multiple batches of preparation of a certain Chinese medical concrete is adopted to carry out determination of moisture respectively, following mathematical model is set up: medicinal extract moisture value=X × microwave moisture measured value+Y according to the correlativity of the two, the foundation of model is through multiple batches of data, at least 10 batches, external certificate, calibration are carried out to data model, obtains final mathematical formulae
2) Method validation
A) precision is investigated
Same sample continuous detecting 6 times, the method precision should well (RAD1.0%≤2%).
B) durability is investigated
Appoint get 1 batch of blood-nourishing and brain-refreshing the water extracted immersing paste respectively at 0 time, within 1 day, 2 days, 3 days, 4 days, carry out rapid microwave determination of moisture, detect with a collection of medicinal extract different time, moisture value answers no significant difference (RAD1.1%≤2%).
C) adaptability is investigated
Get multiple batches of medicinal extract and carry out the investigation of rapid microwave determination of moisture method applicability, medicinal extract baking oven, rapid microwave two kinds of determination of moisture methods measure moisture values and answer no significant difference (RAD≤2.0%).
3) wherein microwave moisture assay method can be adopted with the following method:
1, microwave moisture meter trace routine (mode of operation of embodiment) is set
2, sample determination: get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, record measured value.
4) wherein oven drying method determination of moisture method can be adopted with the following method:
Get test sample 2 ~ 5g, be laid in and be dried in the flat measuring cup of weight, thickness is no more than 5mm, accurately weighed, open bottle cap 100 ~ 105 DEG C of dryings 5 hours, bottle cap is built, in dislocation exsiccator, cool 30 minutes, accurately weighed, then said temperature drying 1 hour, cooling, weigh, to double difference of weighing is no more than 5mg.According to the weight of less loss, calculate water cut (%) in test sample.
5) microwave moisture measured value is substituted into data model: medicinal extract moisture value=X × microwave moisture measured value+Y, calculate moisture value
Three mathematical models detect to the 3 kinds of medicinal extract obtained in blood-nourishing and brain-refreshing granules preparation process the 3 kinds of mathematical models obtained below, and method for building up is shown in embodiment 1-3.
Blood-nourishing and brain-refreshing the water extracted immersing paste moisture value=X × microwave moisture measured value+Y
Wherein X=0.4884, Y=15.465
Blood-nourishing and brain-refreshing alcohol-extracted extract moisture value=X × microwave moisture measured value+Y
Wherein X=0.488, Y=15.367
Root of herbaceous peony medicinal extract moisture value=X × actual microwave moisture measured value+Y
Wherein X=0.6926, Y=10.23
Beneficial effect of the present invention
The alternative oven drying method of rapid microwave determination of moisture method is used for determination of moisture, and because microwave frequency only works to hydrone between 2.4 ~ 2.5GHZ, measured value is more accurate, and can solve Problems existing in oven drying method mensuration medicinal extract moisture process, as:
1, the evaporating dish constant weight time longer (more than 6hr).
2, sample oven dry, weight are to double drying difference within 5mg, and required time long (more than 6hr), takies instrument, human resources.
Even if 3, during sampling, uniform application is on evaporating dish, after placing a few minutes, sample also has and assembles agglomerating situation, has a strong impact on the dry constant weight time.
Rapid microwave determination of moisture method finding speed fast (about 2min), precision good (RAD≤2%), good tolerance (RAD≤2%), and with existing (baking oven) method measured value no significant difference (RAD≤3%).Alternative traditional oven drying method is used for determination of moisture.
Rapid microwave determination of moisture method finding speed is fast, precision is good, good tolerance, and with existing (baking oven) method measured value no significant difference.
Accompanying drawing illustrates:
Fig. 1 blood-nourishing and brain-refreshing the water extracted immersing paste two kinds of determination of moisture method correlation analysiss
Fig. 2 blood-nourishing and brain-refreshing alcohol-extracted extract two kinds of determination of moisture method correlation analysiss
The relationship analysis of Fig. 3 root of herbaceous peony medicinal extract two kinds of determination of moisture method measured values
Embodiment:
Further illustrate the present invention by the following examples.
Test example 1: blood-nourishing and brain-refreshing the water extracted immersing paste rapid microwave determination of moisture method is investigated.1, modeling: set up microwave moisture measured value and baking oven measures moisture value relational model
Analyze
blood-nourishing and brain-refreshing the water extracted immersing paste microwave moisture measured value and oven drying method (existing) determination of moisture value are strong positive correlation.
the mathematical formulae obtained is as follows: blood-nourishing and brain-refreshing the water extracted immersing paste Microwave Water score value=0.4884* microwave moisture measured value+15.465.
2, precision is investigated
Appoint and get 1 batch of blood-nourishing and brain-refreshing the water extracted immersing paste and repeat 6 water content detection, investigate the method precision.
Analyze:
same sample continuous detecting 6 times, the method precision good (RAD1.0%≤2%).
3, durability
Appoint get 1 batch of blood-nourishing and brain-refreshing the water extracted immersing paste respectively at 0 time, within 1 day, 2 days, 3 days, 4 days, carry out rapid microwave determination of moisture, investigate the method durability.
Analyze:
detect with a collection of medicinal extract different time, moisture no significant difference (RAD1.1%≤2%).
4, adaptability is investigated
Get 12 batches of blood-nourishing and brain-refreshing the water extracted immersing pastes and carry out the investigation of rapid microwave determination of moisture method applicability
| Sample number into spectrum | Moisture %(baking oven) | Moisture %(microwave) | RAD% |
| 1 | 26 | 27 | 1.9% |
| 2 | 28 | 27 | 1.8% |
| 3 | 27 | 27 | 0.0% |
| 4 | 27 | 28 | 1.8% |
| 5 | 28 | 27 | 1.8% |
| 6 | 30 | 29 | 1.7% |
| 7 | 28 | 28 | 0.0% |
| 8 | 28 | 27 | 1.8% |
| 9 | 29 | 29 | 0.0% |
| 10 | 28 | 29 | 1.8% |
| 11 | 26 | 26 | 0.0% |
| 12 | 27 | 27 | 0.0% |
Analyze:
blood-nourishing and brain-refreshing the water extracted immersing paste baking oven, rapid microwave two kinds of determination of moisture methods measure moisture value
No significant difference (RAD≤2.0%).
Test example 2: blood-nourishing and brain-refreshing alcohol-extracted extract microwave moisture mensuration methodology is investigated
1, modeling: set up microwave moisture measured value and baking oven measures moisture value relational model
Analyze
blood-nourishing and brain-refreshing alcohol-extracted extract microwave moisture measured value and oven drying method (existing) determination of moisture value are strong positive correlation;
the mathematical formulae obtained is as follows: blood-nourishing and brain-refreshing alcohol-extracted extract Microwave Water score value=0.488* is actual
microwave moisture measured value+15.367.
2, precision is investigated
Get 1 batch of blood-nourishing and brain-refreshing alcohol-extracted extract and repeat 6 water content detection, investigate the method precision
Analyze:
the quick determination of moisture continuous detecting of blood-nourishing and brain-refreshing alcohol-extracted extract microwave 6 times, testing result precision good (RAD≤2.0%).
3, durability
Appoint get 1 batch of blood-nourishing and brain-refreshing the water extracted immersing paste respectively at 0 time, within 1 day, 2 days, 3 days, 4 days, carry out rapid microwave determination of moisture, investigate the method durability
| Time (my god) | 0 | 1 | 2 | 3 | 4 |
| Moisture % | 26 | 27 | 26 | 26 | 26 |
| RAD% | 1.2% |
Analyze: detect with a collection of medicinal extract different time, moisture is without significant change (RAD≤2.0%).4, adaptability is investigated
Get 14 batches of blood-nourishing and brain-refreshing alcohol-extracted extracts and carry out the investigation of rapid microwave determination of moisture method applicability
| Sample number into spectrum | Moisture %(baking oven) | Moisture %(microwave) | RAD% |
| 1 | 26 | 26 | 0.0% |
| 2 | 27 | 26 | 1.9% |
| 3 | 24 | 24 | 0.0% |
| 4 | 26 | 26 | 0.0% |
| 5 | 28 | 27 | 1.8% |
| 6 | 26 | 27 | 1.9% |
| 7 | 26 | 25 | 2.0% |
| 8 | 29 | 29 | 0.0% |
| 9 | 26 | 27 | 1.9% |
| 10 | 26 | 26 | 0.0% |
| 11 | 27 | 26 | 1.9% |
| 12 | 27 | 27 | 0.0% |
| 13 | 25 | 26 | 2.0% |
| 14 | 26 | 27 | 1.9% |
Analyze:
blood-nourishing and brain-refreshing alcohol-extracted extract baking oven, rapid microwave two kinds of determination of moisture methods measure moisture value
No significant difference (RAD≤2.0%)
Test example 3: root of herbaceous peony medicinal extract rapid microwave determination of moisture method is investigated
1, modeling: set up microwave moisture measured value and baking oven measures moisture value relational model
| Numbering | Microwave method moisture % | Oven Method moisture % |
| 1 | 31 | 32 |
| 2 | 29 | 31 |
| 3 | 29 | 32 |
| 4 | 28 | 29 |
| 5 | 27 | 29 |
| 6 | 25 | 29 |
| 7 | 25 | 27 |
| 8 | 24 | 27 |
| 9 | 22 | 26 |
| 10 | 26 | 28 |
| 11 | 27 | 28 |
| 12 | 27 | 27 |
| 13 | 28 | 29 |
Analyze
root of herbaceous peony medicinal extract microwave moisture measured value and oven drying method (existing) determination of moisture value are strong positive correlation.
the mathematical formulae obtained is as follows: the actual Microwave Water of root of herbaceous peony medicinal extract Microwave Water score value=0.6926*
Divide measured value+10.23.
2, precision is investigated
Get 1 batch of root of herbaceous peony medicinal extract and repeat 6 water content detection, investigate the method precision.
Analyze:
the quick determination of moisture continuous detecting of root of herbaceous peony medicinal extract microwave 6 times, precision good (RAD≤2.0%).
3, durability:
Appoint get 1 batch of root of herbaceous peony medicinal extract respectively at 0 time, within 1 day, 2 days, 3 days, 4 days, carry out rapid microwave determination of moisture, investigate the method durability
Analyze:
detect with a collection of medicinal extract different time, moisture value no significant difference (RAD≤2.0%).
4, adaptability is investigated
Get 12 batches of root of herbaceous peony medicinal extract and carry out the investigation of rapid microwave determination of moisture method applicability
| Sample number into spectrum | Moisture %(baking oven) | Moisture %(microwave) | RAD% |
| 1 | 32 | 32 | 0.0% |
| 2 | 31 | 30 | 1.6% |
| 3 | 32 | 31 | 1.6% |
| 4 | 29 | 30 | 1.7% |
| 5 | 29 | 29 | 0.0% |
| 6 | 29 | 28 | 1.8% |
| 7 | 27 | 27 | 0.0% |
| 8 | 27 | 27 | 0.0% |
| 9 | 26 | 26 | 0.0% |
| 10 | 28 | 28 | 0.0% |
| 11 | 28 | 29 | 1.8% |
| 12 | 29 | 30 | 1.7% |
Analyze:
root of herbaceous peony medicinal extract baking oven, rapid microwave two kinds of determination of moisture methods measure moisture value no significant difference (RAD≤2.0%).
Embodiment 1
The preparation of blood-nourishing and brain-refreshing the water extracted immersing paste
Prepared rhizome of rehmannia, reticulate millettia, yncaria stem with hooks, selfheal, the root of Chinese wild ginger, mother-of-pearl extracting in water secondary, the dregs of a decoction discard, and extract concentrates, and adds ethanol alcohol precipitation, leave standstill, and are separated clear liquid, reclaim ethanol, continue to be concentrated into thick paste, for subsequent use.
Embodiment 2
The preparation of blood-nourishing and brain-refreshing alcohol-extracted extract
Radix Angelicae Sinensis, Ligusticum wallichii, cassia seed, corydalis tuber add Diluted Alcohol, refluxing extraction 2 times, and the dregs of a decoction discard, and extract reclaims ethanol, continues to be concentrated into thick paste, for subsequent use.
Embodiment 3
The preparation of root of herbaceous peony medicinal extract
The root of herbaceous peony adds Diluted Alcohol, refluxing extraction 2 times, and the dregs of a decoction discard, and extract reclaims ethanol, continues to be concentrated into thick paste, for subsequent use.
Embodiment 4
The determination of moisture of blood-nourishing and brain-refreshing the water extracted immersing paste
Get two all-glass papers, be placed on the balance of microwave moisture meter
Weigh, get test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, measured value is 21.08%.
Microwave moisture measured value is substituted into mathematical model:
Blood-nourishing and brain-refreshing the water extracted immersing paste moisture value=X × microwave moisture measured value+Y
Wherein X=0.4884, Y=15.465
Result of calculation is: 25.76%
Embodiment 5
The determination of moisture of blood-nourishing and brain-refreshing alcohol-extracted extract
Get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, measured value is 25.02%.
Microwave moisture measured value is substituted into mathematical model:
Blood-nourishing and brain-refreshing alcohol-extracted extract moisture value=X × microwave moisture measured value+Y
Wherein X=0.488, Y=15.367
Result of calculation is: 27.58%
Embodiment 6
The determination of moisture of root of herbaceous peony medicinal extract
Get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, measured value is 19.16%.
Microwave moisture measured value is substituted into mathematical model:
Root of herbaceous peony medicinal extract moisture value=X × actual microwave moisture measured value+Y
Wherein X=0.6926, Y=10.23
Result of calculation is: 23.50%
Claims (10)
1. a rapid microwave determination of moisture method for extract, is characterized in that, said method comprising the steps of:
Step 1, gets medicinal extract microwave moisture meter and detects moisture, record measured value;
Step 2, substitutes into the actual water score value in following data model calculating medicinal extract: the measured value+Y of medicinal extract moisture value=X × microwave moisture meter by the measured value of microwave moisture meter;
Wherein, X, Y are the Relation Parameters of microwave determination of moisture and moisture analysis.
2. method according to claim 1, it is characterized in that, described step 1 method is as follows: get medicinal extract two all-glass papers, the balance being placed in microwave moisture meter is removed the peel and weighs, get medicinal extract sample, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, record measured value.
3. method according to claim 1, is characterized in that, described medicinal extract is any one Chinese medical concrete, comprising: blood-nourishing and brain-refreshing the water extracted immersing paste and blood-nourishing and brain-refreshing alcohol-extracted extract.
4. method according to claim 3, is characterized in that, described X value is: 0.488-0.6926, and described Y value is: 10.23-15.465.
5. method according to claim 1, is characterized in that, described medicinal extract is blood-nourishing and brain-refreshing the water extracted immersing paste, and data model is: blood-nourishing and brain-refreshing the water extracted immersing paste moisture value=X × microwave moisture measured value+Y, wherein X=0.4884, Y=15.465.
6. method according to claim 1, is characterized in that, described medicinal extract is blood-nourishing and brain-refreshing alcohol-extracted extract, and data model is: blood-nourishing and brain-refreshing alcohol-extracted extract moisture value=X × microwave moisture measured value+Y, wherein X=0.488, Y=15.367.
7. method according to claim 1, is characterized in that, described medicinal extract is root of herbaceous peony medicinal extract, and data model is: root of herbaceous peony medicinal extract moisture value=X × actual microwave moisture measured value+Y, wherein X=0.6926, Y=10.23.
8. method according to claim 1, is characterized in that, step 1 method is as follows:
Setting microwave moisture meter parameter
After setting parameter, get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, record measured value.
9. method according to claim 1, is characterized in that, the method for building up of described assay method is as follows:
Adopt microwave method and the sample of these two kinds of methods of traditional furnace drying method to the multiple batches of preparation of a certain Chinese medical concrete to carry out determination of moisture respectively, set up following mathematical model according to the correlativity of the two: medicinal extract moisture value=X × microwave moisture measured value+Y.
10. method according to claim 9, is characterized in that, wherein microwave moisture assay method can be adopted with the following method:
Setting microwave moisture meter parameter:
Sample determination: get two all-glass papers, the balance being placed in microwave moisture meter is weighed, gets test sample 0.1-0.14g, put on an all-glass paper, cover another all-glass paper, pressing, put back to balance, cover detection cell, start to detect, record measured value;
Wherein oven drying method determination of moisture method can be adopted with the following method:
Get test sample 2 ~ 5g, be laid in and be dried in the flat measuring cup of weight, thickness is no more than 5mm, accurately weighed, open bottle cap 100 ~ 105 DEG C of dryings 5 hours, bottle cap is built, in dislocation exsiccator, cool 30 minutes, accurately weighed, again said temperature drying 1 hour, cooling, weighs, to double difference of weighing is no more than 5mg, according to the weight of less loss, calculate water cut in test sample.
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| CN106018685A (en) * | 2016-05-13 | 2016-10-12 | 福建森宝食品集团股份有限公司 | Feed moisture quick measuring method |
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| CN112650320A (en) * | 2020-11-30 | 2021-04-13 | 太极集团重庆涪陵制药厂有限公司 | Alcohol precipitation control method |
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| CN105866185A (en) * | 2016-05-03 | 2016-08-17 | 中国水产科学研究院黄海水产研究所 | Method for detecting content of ciprofloxacin hydrochloride |
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| CN106290405A (en) * | 2016-07-29 | 2017-01-04 | 梧州市自动化技术研究开发院 | A kind of Measuring Moisture Content of Tea data processing method improving certainty of measurement |
| CN111681798A (en) * | 2020-04-30 | 2020-09-18 | 中国辐射防护研究院 | Small-size nuclear facility field radioactivity effluent treatment plant that retires |
| CN111681798B (en) * | 2020-04-30 | 2022-09-27 | 中国辐射防护研究院 | Small-size nuclear facility field radioactivity effluent treatment plant that retires |
| CN112650320A (en) * | 2020-11-30 | 2021-04-13 | 太极集团重庆涪陵制药厂有限公司 | Alcohol precipitation control method |
| CN112650320B (en) * | 2020-11-30 | 2022-05-31 | 太极集团重庆涪陵制药厂有限公司 | Alcohol precipitation control method |
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