CN105010393A - Preparation method of copper and zinc combination antiseptic - Google Patents
Preparation method of copper and zinc combination antiseptic Download PDFInfo
- Publication number
- CN105010393A CN105010393A CN201510360772.0A CN201510360772A CN105010393A CN 105010393 A CN105010393 A CN 105010393A CN 201510360772 A CN201510360772 A CN 201510360772A CN 105010393 A CN105010393 A CN 105010393A
- Authority
- CN
- China
- Prior art keywords
- zinc
- copper
- preparation
- antiseptic
- antimicrobial agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a preparation method of a copper and zinc combination antiseptic. The antiseptic is prepared through compounding and complexing water-soluble carboxymethylcellulose sodium and water-soluble metal copper salt and zinc salt according to a certain mass ratio. The water-soluble carboxymethylcellulose sodium with an excellent antibacterial property is selected as a complexing agent, and the copper salt and zinc salt with antifungal ability and with antibacterial ability only smaller less than that of silver are compounded, so the antibacterial property of the copper and zinc combination antiseptic is greatly better than that of a zinc antiseptic. The preparation method of the copper and zinc combination antiseptic has the advantages of simplicity, green and environmentally-friendly process, and low production cost, and the copper and zinc combination antiseptic has good antibiosis and mildew resistance, and can be applied in packaging materials having direct contact with foods, medicines, cosmetics and other products.
Description
Technical field
The invention belongs to antimicrobial composite material preparations and applicatio technical field, be specifically related to a kind of copper zinc combined antimicrobial agent and preparation method thereof.
Background technology
Along with improving constantly and social sustainable development of people's living standard, the requirement of people to assanation and safety is more and more higher.As everyone knows, noxious bacteria causes human health and has a strong impact on, therefore, and one of elimination and effective anti-bacteria emphasis becoming scientists study.Along with the development of science and technology, arise at the historic moment, as antibiotic plastic, anti-bacteria ceramic, anti-bacterial fibre etc. by adding antibacterial agent thus playing the material of antibiotic effect.
At present, market is applied antibacterial agent mainly silver system, copper system and zinc series antibacterial agent more widely.Though silver-series antibacterial agent has higher sterilizing ability, but cause chemical stability poor because it has higher chemical potential (being 0.798V when 25 DEG C), after being subject to Ultraviolet radiation or heating, silver ion is reduced to argent and is converted into silver oxide immediately, goods are made to become ash, blackening, not only reduce its commercial value, also reduce its anti-microbial property; In addition, silver-series antibacterial agent price is higher, and fungal resistance is more weak.The antibacterial ability of copper series antibacterial agent is only lower than silver, and price is comparatively cheap, and has antimycotic effect.Though zinc series antibacterial agent is without discoloration problem, low price, its anti-microbial property is lower, is used alone zinc series antibacterial agent and cannot meets existing antibacterial requirement.
Therefore, copper series antibacterial agent and zinc series antibacterial agent are carried out composite, greatly can make up the inferior position that zinc series antibacterial agent anti-microbial property is low.Through retrieval Patents document, find no the report of similar copper zinc combined antimicrobial agent.
Summary of the invention
For overcoming the deficiencies in the prior art, the invention provides a kind of preparation method of copper zinc combined antimicrobial agent.
A preparation method for copper zinc combined antimicrobial agent, is characterized in that, the concrete steps of the method are as follows:
A, get 0.1-5g sodium carboxymethylcellulose and add 100ml deionized water, dissolve completely after stirring 8-20h, form uniform clear viscous solution;
B, water-soluble antibiotic property slaine and mantoquita and zinc salt are added in above-mentioned clear viscous solution, mol ratio is antibiotic property slaine: sodium carboxymethylcellulose=1:5-2:1, mantoquita: zinc salt mass ratio=1:20-10:1, stirring mantoquita and zinc salt are dissolved and slowly with sodium carboxymethylcellulose generation complexing, finally form uniform floccule in the solution;
C, employing deionized water are repeatedly washed, are filtered above-mentioned floccule, are placed in 60-120 DEG C of baking oven and dry, obtain pulverous copper zinc combined antimicrobial agent after grinding.
The viscosity of described sodium carboxymethylcellulose is 300-800 mPas or 800-1200 mPas.
Described water-soluble mantoquita is the one in copper nitrate, copper sulphate, copper chloride.
Described water-soluble zinc salt is the one in zinc nitrate, zinc sulphate, zinc chloride.
Copper zinc combined antimicrobial agent of the present invention has following advantage:
1. employing of the present invention itself has the water-soluble carboxymethyl sodium cellulosate of excellent anti-bacterium capability as complexing agent, and anti-microbial property is only second to silver and has the mantoquita of fungal resistance and zinc salt carries out composite, further increase the anti-microbial property of combined antimicrobial agent, compensate for the shortcoming that copper system and zinc series antibacterial agent are used alone, widen the range of application of copper system and zinc series antibacterial agent.
2. copper zinc combined antimicrobial agent of the present invention has that preparation method is simple, technique environmental protection, low production cost, antibacterial and mouldproof are good, can carry out the advantages such as continuity large-scale industrial production.
The present invention be develop a kind ofly prepare simple, technique environmental protection, with low cost, anti-microbial property is only second to silver and has the copper zinc combined antimicrobial agent of fungal resistance, can be applicable to the packaging material of the products such as direct contact food, medicine, cosmetics.
Embodiment
The present invention is described in detail by instantiation below, but protection scope of the present invention is not limited to these embodiments.
Embodiment 1:
Get 1g sodium carboxymethylcellulose and add 100mL deionized water, leave standstill after stirring 12h and form uniform clear viscous solution; Again 0.242g copper nitrate and 0.371g zinc nitrate are joined in above-mentioned clear viscous solution, with sodium carboxymethylcellulose complexing after stirring and dissolving, finally form uniform floccule in the solution; Adopt deionized water repeatedly to wash, filter above-mentioned floccule, be placed in 80 DEG C of baking ovens and dry, after grinding, obtain pulverous copper zinc combined antimicrobial agent.Embodiment 1 synthesize copper zinc combined antimicrobial agent to the anti-microbial property of Escherichia coli, staphylococcus aureus respectively as shown in table 1, table 2.
Embodiment 2:
Get 0.5g sodium carboxymethylcellulose and add 100mL deionized water, leave standstill after stirring 9h and form uniform clear viscous solution; Again 0.065g copper chloride and 0.116g zinc sulphate are joined in above-mentioned clear viscous solution, with sodium carboxymethylcellulose complexing after stirring and dissolving, finally form uniform floccule in the solution; Adopt deionized water repeatedly to wash, filter above-mentioned floccule, be placed in 90 DEG C of baking ovens and dry, after grinding, obtain pulverous copper zinc combined antimicrobial agent.The copper zinc combined antimicrobial agent of the 2-in-1 one-tenth of embodiment to the anti-microbial property of Escherichia coli, staphylococcus aureus respectively as shown in table 1, table 2.
Embodiment 3:
Get 2g sodium carboxymethylcellulose and add 100mL deionized water, leave standstill after stirring 15h and form uniform clear viscous solution; Again 0.308g copper sulphate and 0.261g zinc chloride are joined in above-mentioned clear viscous solution, with sodium carboxymethylcellulose complexing after stirring and dissolving, finally form uniform floccule in the solution; Adopt deionized water repeatedly to wash, filter above-mentioned floccule, be placed in 100 DEG C of baking ovens and dry, after grinding, obtain pulverous copper zinc combined antimicrobial agent.Embodiment 3 synthesize copper zinc combined antimicrobial agent to the anti-microbial property of Escherichia coli, staphylococcus aureus respectively as shown in table 1, table 2.
Embodiment 4:
Get 5g sodium carboxymethylcellulose and add 100mL deionized water, leave standstill after stirring 18h and form uniform clear viscous solution; Again 0.727g copper chloride and 0.326g zinc nitrate are joined in above-mentioned clear viscous solution, with sodium carboxymethylcellulose complexing after stirring and dissolving, finally form uniform floccule in the solution; Adopt deionized water repeatedly to wash, filter above-mentioned floccule, be placed in 60 DEG C of baking ovens and dry, after grinding, obtain pulverous copper zinc combined antimicrobial agent.Embodiment 4 synthesize copper zinc combined antimicrobial agent to the anti-microbial property of Escherichia coli, staphylococcus aureus respectively as shown in table 1, table 2.
The copper zinc combined antimicrobial agent of table 1 embodiment 1, example 2, example 3 and example 4 preparation is to colibacillary anti-microbial property.
Note: detect according to QB/T 21510-2008 detection method and standard.
The copper zinc combined antimicrobial agent of table 2 embodiment 1, example 2, example 3 and example 4 preparation is to the anti-microbial property of staphylococcus aureus
Note: detect according to QB/T 21510-2008 detection method and standard.
Claims (4)
1. a preparation method for copper zinc combined antimicrobial agent, is characterized in that, the concrete steps of the method are as follows:
A, get 0.1-5g sodium carboxymethylcellulose and add 100ml deionized water, dissolve completely after stirring 8-20h, form uniform clear viscous solution;
B, water-soluble antibiotic property slaine and mantoquita and zinc salt are added in above-mentioned clear viscous solution, mol ratio is antibiotic property slaine: sodium carboxymethylcellulose=1:5-2:1, mantoquita: zinc salt mass ratio=1:20-10:1, stirring mantoquita and zinc salt are dissolved and slowly with sodium carboxymethylcellulose generation complexing, finally form uniform floccule in the solution;
C, employing deionized water are repeatedly washed, are filtered above-mentioned floccule, are placed in 60-120 DEG C of baking oven and dry, obtain pulverous copper zinc combined antimicrobial agent after grinding.
2. the preparation method of a kind of copper zinc combined antimicrobial agent according to claim 1, is characterized in that, the viscosity of described sodium carboxymethylcellulose is 300-800 mPas or 800-1200 mPas.
3. the preparation method of copper zinc combined antimicrobial agent according to claim 1, is characterized in that, described water-soluble mantoquita is the one in copper nitrate, copper sulphate, copper chloride.
4. the preparation method of copper zinc combined antimicrobial agent according to claim 1, is characterized in that, described water-soluble zinc salt is the one in zinc nitrate, zinc sulphate, zinc chloride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510360772.0A CN105010393A (en) | 2015-06-26 | 2015-06-26 | Preparation method of copper and zinc combination antiseptic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510360772.0A CN105010393A (en) | 2015-06-26 | 2015-06-26 | Preparation method of copper and zinc combination antiseptic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105010393A true CN105010393A (en) | 2015-11-04 |
Family
ID=54401045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510360772.0A Pending CN105010393A (en) | 2015-06-26 | 2015-06-26 | Preparation method of copper and zinc combination antiseptic |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105010393A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106222718A (en) * | 2016-08-30 | 2016-12-14 | 武汉理工大学 | A kind of electro-deposition method of carboxymethyl cellulose |
| CN106751394A (en) * | 2016-12-07 | 2017-05-31 | 佛山市飞时达新材料科技有限公司 | A kind of antibacterial ABS material and preparation method |
| CN111748422A (en) * | 2020-07-24 | 2020-10-09 | 汪红兵 | Washing machine door seal rubber ring mildew spot remover and preparation method thereof |
| CN114291837A (en) * | 2021-12-30 | 2022-04-08 | 宁夏京成天宝科技有限公司 | Preparation method of antibiotic substitute |
| CN115262020A (en) * | 2022-07-18 | 2022-11-01 | 湖州草本源新材料有限公司 | Nano copper-zinc composite antibacterial fiber and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1048786A (en) * | 1989-07-21 | 1991-01-30 | 天津师范专科学校 | Synthetic and the application of multifunctional agricultural element |
| CN102076911A (en) * | 2008-06-20 | 2011-05-25 | 国际纸业公司 | Composition and recording sheet with improved optical properties |
-
2015
- 2015-06-26 CN CN201510360772.0A patent/CN105010393A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1048786A (en) * | 1989-07-21 | 1991-01-30 | 天津师范专科学校 | Synthetic and the application of multifunctional agricultural element |
| CN102076911A (en) * | 2008-06-20 | 2011-05-25 | 国际纸业公司 | Composition and recording sheet with improved optical properties |
Non-Patent Citations (4)
| Title |
|---|
| ATEF A.IBRAHIM，ABEER M. ADEL，ZEINAB H.ABD EL-WAHAB，等: "《Utilization of carboxymethyl cellulose based on bean hulls as chelating agent. Synthesis, characterization and biological activity》", 《CARBOHYDRATE POLYMERS》 * |
| 李家宁，段新芳，王新爱，等: "《木材防腐剂壳聚糖金属配位聚合物合成条件的优化》", 《西北农林科技大学学报(自然科学版)》 * |
| 王国建: "《功能高分子材料》", 30 June 2014, 同济大学出版社 * |
| 袁艳丽: "《基于糠醛渣的羧甲基纤维素铜配合物的合成与抗菌性研究》", 《河南工业大学硕士学位论文》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106222718A (en) * | 2016-08-30 | 2016-12-14 | 武汉理工大学 | A kind of electro-deposition method of carboxymethyl cellulose |
| CN106751394A (en) * | 2016-12-07 | 2017-05-31 | 佛山市飞时达新材料科技有限公司 | A kind of antibacterial ABS material and preparation method |
| CN106751394B (en) * | 2016-12-07 | 2019-04-23 | 汕头市格派环保科技有限公司 | A kind of antibacterial ABS material and preparation method |
| CN111748422A (en) * | 2020-07-24 | 2020-10-09 | 汪红兵 | Washing machine door seal rubber ring mildew spot remover and preparation method thereof |
| CN114291837A (en) * | 2021-12-30 | 2022-04-08 | 宁夏京成天宝科技有限公司 | Preparation method of antibiotic substitute |
| CN115262020A (en) * | 2022-07-18 | 2022-11-01 | 湖州草本源新材料有限公司 | Nano copper-zinc composite antibacterial fiber and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105010393A (en) | Preparation method of copper and zinc combination antiseptic | |
| CN103783079A (en) | Preparation method of silver-loaded mesoporous inorganic antibacterial agent | |
| CN103981591B (en) | Antibacterial polyester fibre of a kind of copper modification and preparation method thereof | |
| CN103756155B (en) | A kind of Antibacterial PPR pipe | |
| MX2017006335A (en) | Chelated metal oxide gel compositions. | |
| CN104045853A (en) | Ag, Cu and Zn doped nanometer titanium dioxide composite antibacterial agent and preparation method thereof | |
| CN105670092A (en) | LDPE (low-density polyethylene) antibacterial plastic and preparation method therefor | |
| CN103798289A (en) | Preparation method of silver-loaded mesoporous silicon dioxide antibacterial agent | |
| CN108102152A (en) | A kind of food packaging hectorite immobilization nano silver/chitosan anti-bacteria composite membrane and preparation method and application | |
| CN104151796B (en) | A kind of antibacterial anti-oil stains PET plastic packing box | |
| CN105017730A (en) | PET nano-antibacterial composite material | |
| WO2008087845A1 (en) | Aqueous solution composition | |
| CN103589095A (en) | Antibacterial plastic containing natural antibacterial agent | |
| CN107459802A (en) | A kind of polycarbonate plastic of antibacterial | |
| CN105694229A (en) | PP antibacterial plastic and preparation method thereof | |
| CN105801976B (en) | A kind of HDPE antibiotic plastics and preparation method thereof | |
| CN107400282A (en) | A kind of vinyon of antibacterial | |
| CN107459685B (en) | Latex with precipitation-free sterilization function, preparation method and application | |
| CN105647099A (en) | Preparation method of antibacterial ABS resin | |
| CN105670238A (en) | Sterilizing polyester resin | |
| CN103571104A (en) | PVC (poly vinyl chloride) tube material containing glass-based inorganic antibacterial agent | |
| CN105749293A (en) | Oxygen-containing xanthene ketone modified polymer drug as well as preparation method and application thereof in preparation of antibacterial drugs | |
| CN105131336A (en) | Antibacterial agent, preparation method and application thereof | |
| CN105670202A (en) | Antibacterial ABS resin | |
| CN104628008A (en) | Preparation method of antibacterial nano SiO powder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20151104 |
|
| RJ01 | Rejection of invention patent application after publication |