CN104998238A - Therapeutic medicine for Norwalk virus infection - Google Patents

Therapeutic medicine for Norwalk virus infection Download PDF

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Publication number
CN104998238A
CN104998238A CN201510465789.2A CN201510465789A CN104998238A CN 104998238 A CN104998238 A CN 104998238A CN 201510465789 A CN201510465789 A CN 201510465789A CN 104998238 A CN104998238 A CN 104998238A
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parts
norwalk virus
virus infection
medicine
radix
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周振平
李先强
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Abstract

The invention relates to therapeutic medicine for a Norwalk virus infection. According to the theoretical analysis of the traditional Chinese medicine, the phenomena of the Norwalk virus infection comprise that the epidemic disease is strong, the heat toxin is internally closed, the damp and the heat are latent, and the spleen and the kidney are in deficiency of yin. The damp is removed by heat clearing and toxicity removing, blood cooling and qi tonifying are carried out, the fire is discharged, and the lockage is opened. The therapeutic medicine is traditional Chinese medicine which can tonify the spleen and the kidney, induce the astringency and cure the diarrhea. The therapeutic medicine for the Norwalk virus infection comprises 10 parts of coptidis rhizome, 7 parts of fresh ginger, 10 parts of radix scutellariae, 15 parts of sanguisorba officinalis, 10 parts of honeysuckle, 10 parts of moutan bark, 15 parts of dried radix rehmanniae, 10 parts of ginseng, 10 parts of fructus schizandrae, 10 parts of rhubarb, 10 parts of jasmines, 10 parts of puerarin, 10 parts of acorus tatarinowii, 10 parts of fructus psoraleae and 10 parts of evodia. The combining therapy is carried out, the correct theoretical scheme for curing the Norwalk virus infection by the traditional Chinese medicine is created, and the obvious curative effect is achieved.

Description

The medicine that one group of norwalk virus infects
Technical field
The present invention relates to the Chinese medicine that one group of norwalk virus infects, belong to medicine technology field.
Background technology
Nineteen sixty-eight, Cécile Nowak city of the U.S. breaks out an acute diarrhea prevalent condition, and medical researchers is isolated a kind of disease-producing pathogens from the Feces of Patients of diarrhoea, names with place name Cécile Nowak.(Norwalk Viruses, NV) is the prototype representative strains that in mankind's Caliciviridae (Human Calicivirus, HuCV), norovirus (Norovirus, NV) belongs to.The virion that NV is one group of plesiomorphism, antigenicity is slightly different.Norwalk virus is the virus that one group of Calicivirus belongs to, and is also referred to as " norovirus ".Norwalk virus infects and affects harmonization of the stomach intestinal, causes gastroenteritis or " gastrointestinal influenza "." gastrointestinal influenza " is different from the influenza that influenza virus causes respiratory tract disease.Norwalk virus inhabits in the shellfishes such as Concha Ostreae usually, if people eat these contaminated shellfishes raw can be infected, the vomitus of patient and Excreta also can transmitted virus.Norwalk virus can cause diarrhoea, and main clinical manifestation is stomachache, diarrhoea, Nausea and vomiting.It infects mainly through the feces of patient and vomitus, and infectiousness is very strong, and vulnerable old people has the danger that sb.'s illness took a turn for the worse after infection virus.Expert warns, and when giving old man's changing babies' napkin, bank note and scouring vomitus, if only simply cleaned, after dry, norwalk virus can be in atmosphere floating, causes infection, therefore must be noted that sterilization.In addition to notice that duty is washed one's hands.
Norwalk virus cardinal symptom comprises nausea,vomiting,diarrhea and stomachache, part have mild fever, headache, muscular soreness, asthenia, Wry Neck, photophobia, etc. phenomenon.Although infected person can feel serious discomfort, except infant, old man and immunologic function deficiency person, as long as the moisture of supplementary loss that can be suitable, giving supportive treatment symptom can improve within a couple of days.Norwalk virus infects and causes gastroenteritis, and gastroenteritis refers to the inflammation of stomach, small intestinal and large intestine.The symptom of gastroenteritis is Nausea and vomiting, abdominal cramps diarrhoea.Groups of people main suit has headache, heating, shiver with cold, myalgia.Symptom continues 1 ~ 2 day usually.Generally feel to be in a bad way, repeatedly hyperemesis on the one.Within 24 ~ 48 hours, occur after symptom generally takes in virus, but exposing latter 12 hours also may there is symptom.Not evidence suggests that the infected can become long-term virus carrier, but can virus be detected from the feces and vomitus of morbidity 2 weeks the infecteds after rehabilitation.
Norwalk virus does not also have special specific treatment medicine at present, mainly to the symptom symptomatic treatment occurred, receives certain inhibition.
Summary of the invention
Norwalk virus the infected cause of disease is not only the popular of virus, is also the immune resist ability of patient self.Infect with the viewpoint analysis norwalk virus of Chinese medicine, belong to epidemic disease poison stop up contain, close in pyretic toxicity, damp-heat accumulation, nourishing kidney-yin, treatment norwalk virus infects, should with heat-clearing and toxic substances removing removing dampness, removing heat from blood QI invigorating, pathogenic fire purging opening and closing; The Chinese Medicine and Clavicular treatment of warming and recuperating the spleen and kidney, stopping diarrhea with astringents, must receive obvious curative effect.
The medicine that one group of norwalk virus infects combines by each Chinese medicine quality part ratio below: Rhizoma Coptidis 10 parts, 7 parts, Rhizoma Zingiberis Recens, Radix Scutellariae 10 parts, Radix Sanguisorbae 15 parts, Flos Lonicerae 10 parts, Cortex Moutan 10 parts, 15 parts, the Radix Rehmanniae, Radix Ginseng 10 parts, Fructus Schisandrae Chinensis 10 parts, Radix Et Rhizoma Rhei 10 parts, Fructus Gardeniae 10 parts, Radix Puerariae 10 parts, Rhizoma Acori Graminei 10 parts, Fructus Psoraleae 10 parts, Fructus Evodiae 10 parts.
Property of medicine effect of each Chinese medicine ingredients in the medicine that lower surface analysis one group of norwalk virus infects.Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication, for damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire heat in blood tells nosebleed.Rhizoma Zingiberis Recens nature and flavor are pungent, temperature compensation, have the multiple efficacies such as cold expelling diaphoresis, preventing phlegm from forming and stopping coughing, stomach function regulating, preventing or arresting vomiting.Radix Scutellariae has the effect such as heat clearing and damp drying, eliminating fire and detoxication.DIYU SHENGBAI PIAN has effect of benefiting QI and nourishing blood, strengthening spleen, tonifying kidney, blood circulation promoting and blood stasis dispelling.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times, its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, and fragrance thoroughly reaches and can be eliminating evil, and Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis.Cortex Moutan heat clearing away, removing heat from blood and blood, repercussive.The Radix Rehmanniae have clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, matter profit the effect of letting out is fallen.Radix Ginseng effect: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, and Fructus Alpiniae Oxyphyllae of calming the nerves, cures mainly: the deficient syndromes such as impairment caused by overstrain is deficient, food is told in lack of appetite, asthenia, regurgitation, stool lingering diarrhea, empty cough with asthma are urged, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence.Effect of Fructus Schisandrae Chinensis: astringe the lung, nourishing kidney, promotes the production of body fluid, and receive antiperspirant, arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Radix Et Rhizoma Rhei major function is stasis removing, relieving constipation by purgation, stagnates for Gastrointestinal excess heat, constipation.Fructus Gardeniae clearing away heat-fire, removing heat from blood.Fructus Gardeniae resolving heat and reducing pathogenic fire, relieving restlessness diuresis, removing pathogenic heat from blood and toxic substance from the body, cures mainly: calentura is vexed, jaundice, stranguria with blood, dysuria, tells nosebleed hematochezia, heat-virulence in a sore.Radix Puerariae apart from expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, the merit of yang invigorating antidiarrheal.Rhizoma Acori Graminei is had one's ideas straightened out, eliminating phlegm, regulates the flow of vital energy, and invigorates blood circulation, and loose wind, dries, control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, and ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug.Fructus Psoraleae reinforcing the kidney and supporting YANG, controls cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, and deficiency and coldness is breathed heavily and coughed.Fructus Evodiae warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, and stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
The medicine beneficial effect of the invention that one group of norwalk virus infects is: inventor with the theory analysis norwalk virus of Chinese medicine infect belong to epidemic disease poison stop up contain, close in pyretic toxicity, damp-heat accumulation, nourishing kidney-yin, with heat-clearing and toxic substances removing removing dampness, removing heat from blood QI invigorating, pathogenic fire purging opening and closing; The Chinese Medicine and Clavicular treatment of warming and recuperating the spleen and kidney, stopping diarrhea with astringents, has started the correct theory scheme infected with Chinese medicine treatment norwalk virus, and has received obvious curative effect.
Detailed description of the invention
It is combine by each Chinese medicine quality below that the medicine that one group of norwalk virus infects is suitable for a dose drug that a norwalk virus infected patient takes: Rhizoma Coptidis 10 grams, 7 grams, Rhizoma Zingiberis Recens, Radix Scutellariae 10 grams, Radix Sanguisorbae 15 grams, Flos Lonicerae 10 grams of parts, Cortex Moutan 10 grams, 15 grams, the Radix Rehmanniae, Radix Ginseng 10 grams, Fructus Schisandrae Chinensis 10 grams, Radix Et Rhizoma Rhei 10 grams, Fructus Gardeniae 10 grams, Radix Puerariae 10 grams, Rhizoma Acori Graminei 10 grams, Fructus Psoraleae 10 grams, Fructus Evodiae 10 grams.
The medicine using method that one group of norwalk virus infects: decoct soup and take orally, patient with severe symptoms takes a dosage day, and patient with slight symptoms takes a dosage on the 2nd, serve on and can cure with five to ten days.2014, Wuming County Wuming, Guangxi Zhuang Autonomous Region senior middle school outburst norwalk virus infected, and cause a large amount of student and occur diarrhea and vomiting and heating paresthesia, therefore school determines to have a holiday or vacation one week.Reporter recognizes from Wuming County health and Family Planning Bureau, after expert investigation process, assert that teachers and students have infected GII type norwalk virus, accumulative reported cases 213 example.Take rear follow-up investigation by the patient infected 20 many cases norwalk viruses, slow down symptom effective percentage 100% after taking the medicine of this group of norwalk virus infection, coordinate Western medicine cure rate 100%.

Claims (1)

1. the medicine that infects of one group of norwalk virus, is characterized in that combining by each Chinese medicine quality part ratio below: Rhizoma Coptidis 10 parts, 7 parts, Rhizoma Zingiberis Recens, Radix Scutellariae 10 parts, Radix Sanguisorbae 15 parts, Flos Lonicerae 10 parts, Cortex Moutan 10 parts, 15 parts, the Radix Rehmanniae, Radix Ginseng 10 parts, Fructus Schisandrae Chinensis 10 parts, Radix Et Rhizoma Rhei 10 parts, Fructus Gardeniae 10 parts, Radix Puerariae 10 parts, Rhizoma Acori Graminei 10 parts, Fructus Psoraleae 10 parts, Fructus Evodiae 10 parts.
CN201510465789.2A 2015-07-31 2015-07-31 Therapeutic medicine for Norwalk virus infection Pending CN104998238A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103211906A (en) * 2013-05-16 2013-07-24 黎秋萍 Medicinal food used for viral diarrhea

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103211906A (en) * 2013-05-16 2013-07-24 黎秋萍 Medicinal food used for viral diarrhea

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张绪富: "抗诺如病毒药物筛选的相关基础及其有效方药的文献研究", 《医药卫生科技辑》 *
李苑: "《病毒性腹泻防治手册》", 31 October 2011 *

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