CN104997925A - Burn ointment capable of moistening, removing necrotic tissue and promoting granulation, and preparation method thereof - Google Patents

Burn ointment capable of moistening, removing necrotic tissue and promoting granulation, and preparation method thereof Download PDF

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Publication number
CN104997925A
CN104997925A CN201510503120.8A CN201510503120A CN104997925A CN 104997925 A CN104997925 A CN 104997925A CN 201510503120 A CN201510503120 A CN 201510503120A CN 104997925 A CN104997925 A CN 104997925A
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radix
parts
burn
necrotic tissue
promoting granulation
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CN201510503120.8A
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宋宽新
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Abstract

The invention discloses burn ointment capable of moistening, removing necrotic tissue and promoting granulation, and a preparation method thereof. The preparation method includes the following steps: placing coptis chinensis, rheum palmatum, scutellaria baicalensis, phellodendron amurense, sanguisorba officinalis, angelicae sinensis, dried radix rehmanniae, lithospermum erythrorhizon , radix glycyrrhizae and folium artemisiae argyi into sesame oil and soaking for three days, then decocting the materials with slow fire until the materials are charred, filtering, adding beeswax into the filtrate, then adding borneol after the beeswax is melt, and cooling to obtain the reddish brown burn ointment. The burn ointment provided by the invention has the efficacies of removing necrotic tissue, promoting granulation and killing pain effectively, can be used for treating large-area deep burns caused by hot liquid, fire, electric shock, electric arc, strong base, strong acid and oil, and has the advantage of not requiring skin grafting.

Description

A kind of moistening removing the necrotic tissue and promoting granulation burn cream and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to one can removing the necrotic tissue and promoting granulation, potent pain relieving, remove scar hyperplasia, skin-grafting and pain, and cure moistening removing the necrotic tissue and promoting granulation burn cream of the extensive deep burn caused because of reasons such as hydrothermal solution, flame, electric shock, highly basic, strong acid and oils and preparation method thereof.
Background technology
The treatment of present large hospital treatment large area burn and scald is complicated, and costly, patient's misery is many, healing is comparatively slow, and comparatively scar contracture appears in severe one, and causes functional disorder, external-applied ointment general burn medicine generally can only treat either shallow small size burn and scald, helpless to extensive deep burn.Because of the extensive deep burn that the reasons such as hydrothermal solution, flame, electric shock, electric arc, highly basic strong acid cause, the generally last probability having skin-grafting, or leave serious cicatrix and pigment alteration, what have even leaves the sequela such as dysfunction, long for the healing time cycle, bring unnecessary misery to patient, the patient for deep burn occurs that wound surface slough is to the hidden danger causing cicatrix later.
Summary of the invention
In order to part takes above-mentioned the deficiencies in the prior art, the object of this invention is to provide a kind of moistening removing the necrotic tissue and promoting granulation burn cream and preparation method thereof, there is the effect such as removing the necrotic tissue and promoting granulation, potent pain relieving, cure the extensive deep burn because the reasons such as hydrothermal solution, flame, electric shock, electric arc, highly basic strong acid and oils cause, without the need to the feature of making skin graft.
To achieve these goals, the technical solution used in the present invention is:
A kind of moistening removing the necrotic tissue and promoting granulation burn cream, is characterized in that, comprise following number proportioning:
Rhizoma Coptidis 8 ~ 10 parts; Radix Et Rhizoma Rhei 10 ~ 15 parts; Radix Scutellariae 10 ~ 12 parts; Cortex Phellodendri 10 ~ 12 parts; Radix Sanguisorbae 12 ~ 15 parts; Radix Angelicae Sinensis 10 ~ 12 parts; 10 ~ 12 parts, the Radix Rehmanniae; Radix Arnebiae (Radix Lithospermi) 5 ~ 8 parts; 3 ~ 6 parts, Radix Glycyrrhizae; Borneolum Syntheticum 0.5 ~ 1 part; 30 ~ 60 parts, Cera Flava; Folium Artemisiae Argyi 3 ~ 5 parts; Oleum sesami 500 ~ 1000 parts.
A preparation method for moistening removing the necrotic tissue and promoting granulation burn cream, is characterized in that, comprise the following steps:
Rhizoma Coptidis, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Radix Sanguisorbae, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae, Folium Artemisiae Argyi are placed in Oleum sesami and soak 3 days, then slow fire boils when Jiao sent out by medicine and filters, in filtrate, place Cera Flava, after Cera Flava dissolves, put into Borneolum Syntheticum, after cooling both burn cream russet.
In above-described 11, the property of medicine of Chinese medicinal components is as follows:
1, Rhizoma Coptidis
Cure mainly: pyretic toxicity, the burning hot wound of soup;
2, Radix Et Rhizoma Rhei
Cure mainly: purge heat poison, and removing mass is stagnant, clots absorbing blood, edema furuncle, burn;
3, Radix Scutellariae
Cure mainly: clearing away heat-fire, dampness is detoxified, hemostasis;
4, Cortex Phellodendri
Cure mainly: heat clearing away, dampness, pathogenic fire purging, removing toxic substances.
5, Radix Sanguisorbae
Cure mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore, burn due to hot liquid or fire, carbuncle sore tumefacting virus;
6, Radix Angelicae Sinensis
Cure mainly: enrich blood, invigorate blood circulation;
7, the Radix Rehmanniae
Cure mainly: clearing away heat and cooling blood, promote the production of body fluid and moisturize, traumatic pain, carbuncle;
8, Radix Arnebiae (Radix Lithospermi)
Cure mainly: removing heat from blood, invigorate blood circulation, removing toxic substances, scald;
9, Radix Glycyrrhizae
Cure mainly: QI invigorating invigorating middle warmer, relieving spasm to stop pain;
10, Borneolum Syntheticum
Cure mainly: logical all keys, loose stagnated fire, reducing swelling and alleviating pain.
11, Folium Artemisiae Argyi
Cure mainly: blood of regulating the flow of vital energy, by cold-damp; Hemostasis.
The invention has the beneficial effects as follows:
1) healing speed shortens half than like product, and I degree of burn can be fully recovered for 2 days, within Superficial bums 4-6 days, can fully recover, and within about deepⅱdegreeburn 9-12 days, can fully recover, the recovery from illness in about 25 ~ 35 days of III degree of burn, and can reach without scar healing or thin scar.
2) within one day, only need change dressings once, simple debridement must be done to wound surface, wound surface dressing after coating, the wet treatment of forefront can make the automatic Liquefaction of wound surface, and keep wound surface moistening, slough is got rid of in liquefaction, make remaining tissue bring back to life regeneration, epithelial tissue reaches reparation fast.
3) the safest painless pure Chinese medicine formula, Chinese medicine pain relieving, Patients with Big Area Burn, after smearing ointment, gets final product pain relieving in about 15 minutes.
4) always for clinical trial, successful, without obvious pain after patient's drug of topical application, can wound healing as early as possible; prevent and reduce the generation of cicatrix, there is removing the necrotic tissue and promoting granulation, cooling blood for hemostasis; the effects such as potent pain relieving, non-stimulated to injury region, pain sensation peripheral nerve can be protected in moist environment.
5) can treat extensive deep burn (, two, three degree), current domestic general burn cream can only treat one, two degree of small size burn and scald, has without the advantage in analogy.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further, but this programme is not limited to following examples:
A kind of moistening removing the necrotic tissue and promoting granulation burn cream, gets Rhizoma Coptidis 8 grams, Radix Et Rhizoma Rhei 10 grams, Radix Scutellariae 10 grams, Cortex Phellodendri 10 grams, Radix Sanguisorbae 12 grams, Radix Angelicae Sinensis 10 grams, 10 grams, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi) 5 grams; 3 grams, Radix Glycyrrhizae; Folium Artemisiae Argyi 3 grams is placed in 500 grams of Oleum sesami and soaks 3 days, and then slow fire boils when Jiao sent out by medicine and filters, and places 30 grams of Cera Flavas, put into 0.5 Borneolum Syntheticum after Cera Flava dissolves in filtrate, after cooling both burn cream russet.
Be below clinical implementation case:
1, one-year-old half people from Lintong of Lv man
Thorax abdomen scalded by boiled water, right lower extremity thigh calf and right foot 1 day, skin injury at that time, and wound surface substrate is red and white, and sepage is few, and touch a tender spot slightly responsive, deep second degree burn, area 18%, through treating recovery from illness in 15 days, without cicatrix.
2, Chen man 63 years old Yan my good man
Boiled water scalds right foot 17 days, skin injury when seeking medical advice, and wound surface substrate white, without sepage, touches a tender spot blunt., there is slough in traumatic infection, tentative diagnosis three degree scald, area 2%, and through a treatment in month, wound surface substrate pale red, had slight thin scar.
3, so-and-so female of model 49 years old people from Lintong
Right lower extremity thigh calf boiled water scalds 1 hour, skin injury at that time, and wound surface substrate is red and white, and sepage is few, touches a tender spot slightly responsive, the treatment recovery from illness in 8%, 17 days of dark two degree of scalding areas, without cicatrix, and local skin pigment alteration.
4, marquis man 2 years old people from Weinan
Right lower extremity boiled water is scalded, and within one day, treats afterwards, skin injury at that time, and wound surface bubbles, and wound surface substrate is red, and sepage is few, touches a tender spot responsive, two degree of scalds, and area 3%, cured after five days, and without cicatrix, non-pigment changes.
5, Liu man 30 years old people from Weinan
Diesel oil burn face one day, skin injury at that time, wound surface substrate peony, sepage is few, slightly responsive deep second degree burn of touching a tender spot, area 3%, cures through seven days, and without cicatrix, non-pigment changes.
6, Mr. Zou man 42 years old Xi'an
The electric burn right upper extremity forearm right hand one hour, skin was burned black at that time, smell of burning weight, and wound surface substrate is red and white, touched a tender spot slightly responsive, and without sepage, deep second degree burn, area 4%, through treatment recovery from illness in 10 days, without cicatrix.
7, Mr. Gao man 23 people from Fuping
The right hand and right lower extremity petrol burn, accept treatment after one week, traumatic infection, skin injury, and wound surface substrate is red and white, touches a tender spot slightly responsive, deep second degree burn, area 4%, and through treatment recovery from illness in 25 days, without cicatrix, non-pigment changed.
8, certain man tall 14 years old people from Xi'an
Left knee joint fire burn, accepts treatment after 13 days, traumatic infection, wound surface substrate pale asphyxia, without sepage, touches a tender spot blunt, third degree burn, area 2%, cures, have mild scar through 30 days.

Claims (2)

1. a moistening removing the necrotic tissue and promoting granulation burn cream, is characterized in that, comprises following number proportioning:
Rhizoma Coptidis 8 ~ 10 parts; Radix Et Rhizoma Rhei 10 ~ 15 parts; Radix Scutellariae 10 ~ 12 parts; Cortex Phellodendri 10 ~ 12 parts; Radix Sanguisorbae 12 ~ 15 parts; Radix Angelicae Sinensis 10 ~ 12 parts; 10 ~ 12 parts, the Radix Rehmanniae; Radix Arnebiae (Radix Lithospermi) 5 ~ 8 parts; 3 ~ 6 parts, Radix Glycyrrhizae; Borneolum Syntheticum 0.5 ~ 1 part; 30 ~ 60 parts, Cera Flava; Folium Artemisiae Argyi 3 ~ 5 parts; Oleum sesami 500 ~ 1000 parts.
2. a preparation method for moistening removing the necrotic tissue and promoting granulation burn cream, is characterized in that, comprise the following steps:
Rhizoma Coptidis, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri, Radix Sanguisorbae, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae, Folium Artemisiae Argyi are placed in Oleum sesami and soak 3 days, then slow fire boils when Jiao sent out by medicine and filters, in filtrate, place Cera Flava, after Cera Flava dissolves, put into Borneolum Syntheticum, after cooling both burn cream russet.
CN201510503120.8A 2015-08-17 2015-08-17 Burn ointment capable of moistening, removing necrotic tissue and promoting granulation, and preparation method thereof Pending CN104997925A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686027A (en) * 2018-08-03 2018-10-23 邓怀展 The antibacterial ointment of scalds and burns putrefaction-removing granulation-promoting and preparation method
CN113181265A (en) * 2021-03-18 2021-07-30 宋坤 Five-red ointment for treating burn and its preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011487A (en) * 2007-02-09 2007-08-08 李笑银 Externally used Chinese patent drug for treating burn and scald and its preparation
CN103800591A (en) * 2012-11-09 2014-05-21 张润渊 Burn ointment

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011487A (en) * 2007-02-09 2007-08-08 李笑银 Externally used Chinese patent drug for treating burn and scald and its preparation
CN103800591A (en) * 2012-11-09 2014-05-21 张润渊 Burn ointment

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
何素玲等: "中药及其外用制剂治疗烧伤的研究进展", 《2014年中国药学大会暨第十四届中国药师周论文集》 *
刘本俊等: "黄连解毒膏的制备及临床应用研究", 《基层中药杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686027A (en) * 2018-08-03 2018-10-23 邓怀展 The antibacterial ointment of scalds and burns putrefaction-removing granulation-promoting and preparation method
CN113181265A (en) * 2021-03-18 2021-07-30 宋坤 Five-red ointment for treating burn and its preparation

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Application publication date: 20151028