CN104997905A - Traditional Chinese medicine lotion for external use for treating skin pruritus and preparation method thereof - Google Patents
Traditional Chinese medicine lotion for external use for treating skin pruritus and preparation method thereof Download PDFInfo
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- CN104997905A CN104997905A CN201510433459.5A CN201510433459A CN104997905A CN 104997905 A CN104997905 A CN 104997905A CN 201510433459 A CN201510433459 A CN 201510433459A CN 104997905 A CN104997905 A CN 104997905A
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- 208000003251 Pruritus Diseases 0.000 title claims abstract description 28
- 239000003814 drug Substances 0.000 title claims abstract description 25
- 239000006210 lotion Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 17
- 239000000706 filtrate Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000000227 grinding Methods 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 239000008280 blood Substances 0.000 abstract description 7
- 210000004369 blood Anatomy 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract description 7
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 230000007803 itching Effects 0.000 abstract description 2
- 244000052769 pathogen Species 0.000 abstract description 2
- 241000123589 Dipsacus Species 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 235000001855 Portulaca oleracea Nutrition 0.000 abstract 1
- 241000219304 Portulacaceae Species 0.000 abstract 1
- 241000246044 Sophora flavescens Species 0.000 abstract 1
- 239000006286 aqueous extract Substances 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 16
- 230000000694 effects Effects 0.000 description 14
- 210000004185 liver Anatomy 0.000 description 8
- 210000003734 kidney Anatomy 0.000 description 6
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000001139 anti-pruritic effect Effects 0.000 description 3
- 239000003908 antipruritic agent Substances 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 210000002429 large intestine Anatomy 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 210000003932 urinary bladder Anatomy 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
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- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
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- 206010023126 Jaundice Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940125715 antihistaminic agent Drugs 0.000 description 1
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- 210000000988 bone and bone Anatomy 0.000 description 1
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- 229940126678 chinese medicines Drugs 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
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- 206010037844 rash Diseases 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
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- 230000008961 swelling Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
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- 231100000397 ulcer Toxicity 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
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- 239000011718 vitamin C Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
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Abstract
The invention discloses traditional Chinese medicine lotion for external use for treating skin pruritus and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine lotion is prepared by, by weight, the aqueous extracts of the following raw materials of 10-30 parts of purslane, 10-30 parts of fructus kochiae, 5-15 parts of herba artemisiae scopariae, 5-15 parts of mint, 10-20 parts of cortex phellodendri, 10-20 parts of sophora flavescens, 10-20 parts of teasel roots, 10-20 parts of fructus cnidii and 10-20 parts of red peony roots. According to the traditional Chinese medicine lotion for external use for treating the skin pruritus and the preparation method thereof, the location has the efficacy of dispelling wind, clearing damp, clearing heat, removing toxicity, nourishing blood, moistening dryness, promoting blood circulation, dispersing blood stasis, eliminating pathogens, strengthening the body resistance and relieving itching, and the skin pruritus can be effectively prevented and treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine external use lotion for the treatment of skin pruritus and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Skin pruritus is in rising trend in recent years, the mainly application of a large amount of chemical article, and environmental pollution, or the reaction of the epidermis of intrinsic disease.Skin pruritus causes spiritual injury to patient, even affects working and learning.If scratched with hands during skin pruritus, usually can be hemorrhage, easily cause infection.
In current treatment skin pruritus, Western medicine is more, as the oral antihistamines in Western medicine, calcium preparation, vitamin A, vitamin C and compound vitamin B.The medicine of existing treatment skin pruritus, some side effect are too large, poor effect, and having of having uses taboo.The traditional Chinese medical science then thinks that primary disease belongs to blood-deficiency and wind-dry, and the suitable blood-nourishing skin-moisturizing for the treatment of, dispelling wind is antipruritic.
Summary of the invention
The object of the invention is to make up the deficiencies in the prior art, a kind of Chinese medicine external use lotion for the treatment of skin pruritus and preparation method thereof is provided.Lotion of the present invention, has dispelling wind damp eliminating, heat-clearing and toxic substances removing, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, effect that righting of getting rid of evils is antipruritic, can effectively treat and prevent and treat skin pruritus.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of Chinese medicine external use lotion for the treatment of skin pruritus, is made up of the water extract of the raw material of following parts by weight: Herba Portulacae 10 ~ 30 parts, the Fructus Kochiae 10 ~ 30 parts, Herba Artemisiae Scopariae 5 ~ 15 parts, Herba Menthae 5 ~ 15 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts and Radix Paeoniae Rubra 10 ~ 20 parts.
The function of several components that Chinese medicine additive of the present invention adopts is respectively:
Herba Portulacae, sour in the mouth, cold in nature, GUIXIN, liver, spleen, large intestine channel, have clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quench the thirst, effect of diuresis; The Fructus Kochiae, sweet in the mouth, hardship, cold in nature, return kidney, urinary bladder channel, have effect of clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching; Herba Artemisiae Scopariae, bitter in the mouth, pungent, cold nature, returns spleen, stomach, liver, gallbladder meridian, has effect of clearing away damp-heat, jaundice eliminating subcutaneous ulcer; Herba Menthae, acrid in the mouth, cool in nature, return lung, Liver Channel, have effect of dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, soothing the liver circulation of qi promoting; Cortex Phellodendri, bitter in the mouth, cold in nature, return kidney, bladder, large intestine channel, have effect of heat clearing and damp drying, eliminating fire and detoxication; Radix Sophorae Flavescentis, bitter in the mouth, cold in nature, GUIXIN, liver, stomach, large intestine, urinary bladder channel, have effect of heat clearing and damp drying, wind dispelling insecticide; Radix Dipsaci, acrid in the mouth, sweet, bitter, slightly warm in nature, returns liver, kidney channel, has effect of invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating; Fructus Cnidii, acrid in the mouth, hardship, warm in nature, return kidney channel, have warming the kidney to invigorate YANG, dampness, dispel the wind, effect of parasite killing; Radix Paeoniae Rubra, bitter in the mouth, cold nature, returns Liver Channel, has effect of clots absorbing, pain relieving, removing heat from blood, detumescence.
On the basis of technique scheme, the present invention can also do following improvement.
Further, be made up of the water extract of the raw material of following parts by weight: Herba Portulacae 20 parts, the Fructus Kochiae 20 parts, Herba Artemisiae Scopariae 10 parts, Herba Menthae 10 parts, Cortex Phellodendri 15 parts, Radix Sophorae Flavescentis 15 parts, Radix Dipsaci 15 parts, Fructus Cnidii 15 parts and Radix Paeoniae Rubra 15 parts.
Treat a preparation method for the Chinese medicine external use lotion of skin pruritus, comprise the steps:
(1) the following raw material through abundant bake drying is chosen: Herba Portulacae, the Fructus Kochiae, Herba Artemisiae Scopariae, Herba Menthae, Cortex Phellodendri, Radix Sophorae Flavescentis, Radix Dipsaci, Fructus Cnidii and Radix Paeoniae Rubra;
(2) above-mentioned raw materials of following parts by weight is taken respectively: Herba Portulacae 10 ~ 30 parts, the Fructus Kochiae 10 ~ 30 parts, Herba Artemisiae Scopariae 5 ~ 15 parts, Herba Menthae 5 ~ 15 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts and Radix Paeoniae Rubra 10 ~ 20 parts, grinding and sieving, after mix homogeneously, add 8 times of weight water and soak 30 minutes, decoct 2 ~ 3 hours, filter to get filtrate, in filtering residue, add 4 times amount soak by water continue 1 ~ 2 hour, filter to get filtrate, merge twice filtrate, obtain the Chinese medicine external use lotion of described treatment skin pruritus.
On the basis of technique scheme, the present invention can also do following improvement.
Further, the parts by weight of step (2) described raw material are respectively: Herba Portulacae 20 parts, the Fructus Kochiae 20 parts, Herba Artemisiae Scopariae 10 parts, Herba Menthae 10 parts, Cortex Phellodendri 15 parts, Radix Sophorae Flavescentis 15 parts, Radix Dipsaci 15 parts, Fructus Cnidii 15 parts and Radix Paeoniae Rubra 15 parts.
Further, the order number sieved described in step (2) is 100 orders.
The invention has the beneficial effects as follows:
(1) lotion of the present invention, has dispelling wind damp eliminating, heat-clearing and toxic substances removing, blood enriching and dryness moistening, blood circulation promoting and blood stasis dispelling, effect that righting of getting rid of evils is antipruritic, can effectively treat and prevent and treat skin pruritus, and instant effect, short treating period, cure rate is high.
(2) the present invention is pure Chinese medicine formula, has no side effect, can life-time service.
(3) preparation method of the present invention is simple, cost is low, be applicable to large-scale production.
Detailed description of the invention
Be described principle of the present invention and feature below in conjunction with specific embodiment, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1:
(1) the following raw material through abundant bake drying is chosen: Herba Portulacae, the Fructus Kochiae, Herba Artemisiae Scopariae, Herba Menthae, Cortex Phellodendri, Radix Sophorae Flavescentis, Radix Dipsaci, Fructus Cnidii and Radix Paeoniae Rubra;
(2) above-mentioned raw materials of following weight is taken respectively: Herba Portulacae 10kg, Fructus Kochiae 30kg, Herba Artemisiae Scopariae 5kg, Herba Menthae 15kg, Cortex Phellodendri 10kg, Radix Sophorae Flavescentis 20kg, Radix Dipsaci 10kg, Fructus Cnidii 20kg and Radix Paeoniae Rubra 10kg, 100 mesh sieves are crossed after pulverizing, after mix homogeneously, add 8 times amount water soaking 30 minutes, decoct 2 hours, filter to get filtrate, in filtering residue, add 4 times amount soak by water continue 1 hour, filter to get filtrate, merge twice filtrate, obtain the Chinese medicine external use lotion of described treatment skin pruritus.
Embodiment 2:
(1) the following raw material through abundant bake drying is chosen: Herba Portulacae, the Fructus Kochiae, Herba Artemisiae Scopariae, Herba Menthae, Cortex Phellodendri, Radix Sophorae Flavescentis, Radix Dipsaci, Fructus Cnidii and Radix Paeoniae Rubra;
(2) above-mentioned raw materials of following weight is taken respectively: Herba Portulacae 20kg, Fructus Kochiae 20kg, Herba Artemisiae Scopariae 10kg, Herba Menthae 10kg, Cortex Phellodendri 15kg, Radix Sophorae Flavescentis 15kg, Radix Dipsaci 15kg, Fructus Cnidii 15kg and Radix Paeoniae Rubra 15kg, 100 mesh sieves are crossed after pulverizing, after mix homogeneously, add 8 times amount water soaking 30 minutes, decoct 2.5 hours, filter to get filtrate, in filtering residue, add 4 times amount soak by water continue 1.5 hours, filter to get filtrate, merge twice filtrate, obtain the Chinese medicine external use lotion of described treatment skin pruritus.
Embodiment 3:
(1) the following raw material through abundant bake drying is chosen: Herba Portulacae, the Fructus Kochiae, Herba Artemisiae Scopariae, Herba Menthae, Cortex Phellodendri, Radix Sophorae Flavescentis, Radix Dipsaci, Fructus Cnidii and Radix Paeoniae Rubra;
(2) above-mentioned raw materials of following weight is taken respectively: Herba Portulacae 30kg, Fructus Kochiae 10kg, Herba Artemisiae Scopariae 15kg, Herba Menthae 5kg, Cortex Phellodendri 20kg, Radix Sophorae Flavescentis 10kg, Radix Dipsaci 20kg, Fructus Cnidii 10kg and Radix Paeoniae Rubra 20kg, 100 mesh sieves are crossed after pulverizing, after mix homogeneously, add 8 times amount water soaking 30 minutes, decoct 3 hours, filter to get filtrate, in filtering residue, add 4 times amount soak by water continue 2 hours, filter to get filtrate, merge twice filtrate, obtain the Chinese medicine external use lotion of described treatment skin pruritus.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (5)
1. treat the Chinese medicine external use lotion of skin pruritus for one kind, it is characterized in that, be made up of the water extract of the raw material of following parts by weight: Herba Portulacae 10 ~ 30 parts, the Fructus Kochiae 10 ~ 30 parts, Herba Artemisiae Scopariae 5 ~ 15 parts, Herba Menthae 5 ~ 15 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts and Radix Paeoniae Rubra 10 ~ 20 parts.
2. a kind of Chinese medicine external use lotion for the treatment of skin pruritus according to claim 1, it is characterized in that, be made up of the water extract of the raw material of following parts by weight: Herba Portulacae 20 parts, the Fructus Kochiae 20 parts, Herba Artemisiae Scopariae 10 parts, Herba Menthae 10 parts, Cortex Phellodendri 15 parts, Radix Sophorae Flavescentis 15 parts, Radix Dipsaci 15 parts, Fructus Cnidii 15 parts and Radix Paeoniae Rubra 15 parts.
3. treat a preparation method for the Chinese medicine external use lotion of skin pruritus, it is characterized in that, comprise the steps:
(1) the following raw material through abundant bake drying is chosen: Herba Portulacae, the Fructus Kochiae, Herba Artemisiae Scopariae, Herba Menthae, Cortex Phellodendri, Radix Sophorae Flavescentis, Radix Dipsaci, Fructus Cnidii and Radix Paeoniae Rubra;
(2) above-mentioned raw materials of following parts by weight is taken respectively: Herba Portulacae 10 ~ 30 parts, the Fructus Kochiae 10 ~ 30 parts, Herba Artemisiae Scopariae 5 ~ 15 parts, Herba Menthae 5 ~ 15 parts, Cortex Phellodendri 10 ~ 20 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Fructus Cnidii 10 ~ 20 parts and Radix Paeoniae Rubra 10 ~ 20 parts, grinding and sieving, after mix homogeneously, add 8 times of weight water and soak 30 minutes, decoct 2 ~ 3 hours, filter to get filtrate, in filtering residue, add 4 times amount soak by water continue 1 ~ 2 hour, filter to get filtrate, merge twice filtrate, obtain the Chinese medicine external use lotion of described treatment skin pruritus.
4. a kind of preparation method for the treatment of the Chinese medicine external use lotion of skin pruritus according to claim 3, it is characterized in that, the parts by weight of step (2) described raw material are respectively: Herba Portulacae 20 parts, the Fructus Kochiae 20 parts, Herba Artemisiae Scopariae 10 parts, Herba Menthae 10 parts, Cortex Phellodendri 15 parts, Radix Sophorae Flavescentis 15 parts, Radix Dipsaci 15 parts, Fructus Cnidii 15 parts and Radix Paeoniae Rubra 15 parts.
5. a kind of preparation method for the treatment of the Chinese medicine external use lotion of skin pruritus according to claim 3, is characterized in that, the order number sieved described in step (2) is 100 orders.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560601A (en) * | 2016-01-28 | 2016-05-11 | 湖南中医药大学第一附属医院（中医临床研究所） | Traditional Chinese medicine composition and preparation for relieving skin itching and preparation method and application thereof |
| CN106215058A (en) * | 2016-08-23 | 2016-12-14 | 彭友莲 | A kind of lotion treating skin pruritus and preparation method thereof |
| CN106389987A (en) * | 2016-11-30 | 2017-02-15 | 卢广成 | Traditional Chinese medicine lotion for treating skin itch and preparation method thereof |
| CN107233406A (en) * | 2017-07-10 | 2017-10-10 | 陈永山 | A kind of traditional Chinese medicine for outer use for treating hormone face |
| CN107669730A (en) * | 2017-11-14 | 2018-02-09 | 大姚县回春堂彝族医药研究所 | A kind of Yi nationality's medicine gynecological lotion and preparation method thereof |
| CN109045280A (en) * | 2018-09-10 | 2018-12-21 | 因之彩生物科技（武汉）有限公司 | A kind of topical composition and its application and remedy for external use |
| CN109771615A (en) * | 2019-03-28 | 2019-05-21 | 昆明医科大学第一附属医院 | A kind of dermatitis and eczema external fumigation and washing Chinese medicinal formulae |
| CN111759910A (en) * | 2020-08-07 | 2020-10-13 | 孙俊杰 | Gardenia cream capable of effectively improving skin |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560601A (en) * | 2016-01-28 | 2016-05-11 | 湖南中医药大学第一附属医院（中医临床研究所） | Traditional Chinese medicine composition and preparation for relieving skin itching and preparation method and application thereof |
| CN106215058A (en) * | 2016-08-23 | 2016-12-14 | 彭友莲 | A kind of lotion treating skin pruritus and preparation method thereof |
| CN106389987A (en) * | 2016-11-30 | 2017-02-15 | 卢广成 | Traditional Chinese medicine lotion for treating skin itch and preparation method thereof |
| CN107233406A (en) * | 2017-07-10 | 2017-10-10 | 陈永山 | A kind of traditional Chinese medicine for outer use for treating hormone face |
| CN107669730A (en) * | 2017-11-14 | 2018-02-09 | 大姚县回春堂彝族医药研究所 | A kind of Yi nationality's medicine gynecological lotion and preparation method thereof |
| CN109045280A (en) * | 2018-09-10 | 2018-12-21 | 因之彩生物科技（武汉）有限公司 | A kind of topical composition and its application and remedy for external use |
| CN109771615A (en) * | 2019-03-28 | 2019-05-21 | 昆明医科大学第一附属医院 | A kind of dermatitis and eczema external fumigation and washing Chinese medicinal formulae |
| CN111759910A (en) * | 2020-08-07 | 2020-10-13 | 孙俊杰 | Gardenia cream capable of effectively improving skin |
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| CN104997905B (en) | 2018-03-23 |
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