CN104937086A

CN104937086A - O/W microemulsion composition

Info

Publication number: CN104937086A
Application number: CN201380052291.2A
Authority: CN
Inventors: 松下高大; 菅原祥太
Original assignee: V Mane Fils SAS
Current assignee: V Mane Fils SAS
Priority date: 2012-10-26
Filing date: 2013-10-24
Publication date: 2015-09-23
Also published as: MX2015002829A; MX364687B; JPWO2014065346A1; BR112015007567B1; WO2014065346A1; JP6411216B2; BR112015007567A2; CL2015001051A1

Abstract

The purpose of the present invention is to provide technology for stably emulsifying a liquid composition containing a terpenoid while said liquid composition is in a transparent state. Provided is an O/W microemulsion that comprises (A) an essential oil containing a terpenoid, (B) ethanol, (C) a polyglycerin fatty acid ester, and (D) a polyoxyethylene sorbitan fatty acid ester, and in which (A):(B) = 1:2.5-40 in terms of mass.

Description

O/W micro emulsion composition

Technical field

The present invention relates to O/W micro emulsion composition.

Background technology

Usually by being mixed with tensio-active agent by lipid-soluble substance in advance, interpolation water or warm water, and emulsifying mixt equably, make lipid-soluble substance be dissolved in aqueous solvent.But, the emulsion that a lot of oil-soluble substance is stable and transparent in formation is had any problem, even if when use has the tensio-active agent of emulsifying capacity.Devise the combination of numerous emulsifiers to address this problem and to improve emulsifying stability.

Such as, patent documentation (PTL) 1 proposes O/W emulsifying composition, and wherein lipid-soluble substance such as salad oil is dissolved by the combination of Quillaia saponaria (Quillaja) saponin(e, polyoxyethylene sorbitan fatty acid ester and ethanol.And PTL 2 discloses and comprises fat-soluble medicine (such as, VITAMIN), polyglycerol fatty acid ester, emulsifying composition based on polyoxyethylated nonionic surface active agent, water-soluble polyol and water.

But even if by technology disclosed in PTL 1 and PTL 2, stably emulsification is difficult with the composition comprised containing the essential oil of terpenes of transparent state.And quillaja-saponin required in technology disclosed in PTL 1 is relatively expensive; Therefore, under nearest economic situation, expect the use reducing this type of material.In addition, required in technology disclosed in PTL 2 polyvalent alcohol causes the taste of wondering when using in foodstuff applications.For these reasons, expect the exploitation of alternative technology.

Reference listing

Patent documentation

PTL 1:JP2010-142205A

PTL 2:JP2004-277375A

Summary of the invention

Technical problem

Based on present situation, target of the present invention is to provide for stably emulsification with the technology comprising the liquid composition of terpenes of transparent state, and provides the novelty product utilizing this technology.

The solution of problem

Present inventor has performed further investigation to reach above target, and therefore find, by making with specific essential oil and alcohol ratio can obtain the micro emulsion composition with excellent transparency and stability containing the combination of the essential oil of terpenes, ethanol, polyglycerol fatty acid ester and polyoxyethylene sorbitan fatty acid ester, and do not need to use quillaja-saponin or polyvalent alcohol.Present inventor has performed further research and the further improvement carried out based on these discoveries.As a result, complete the present invention.

Typical pattern of the present invention is shown following.

1st. a kind of O/W micro emulsion composition, comprises:

(A) containing the essential oil of terpenes,

(B) ethanol,

(C) polyglycerol fatty acid ester, and

(D) polyoxyethylene sorbitan fatty acid ester;

Described O/W micro emulsion composition has (A) of 1:2.5 to 40 in mass than (B) ratio.

2nd. according to the O/W micro emulsion composition of the 1st, wherein said O/W micro emulsion composition has (A) of 1:3 to 20 in mass than (C) ratio.

3rd. according to the 1st or the O/W micro emulsion composition of 2, wherein said O/W micro emulsion composition has (A) of 1:0.1 to 3 in mass than (D) ratio.

4th. the O/W micro emulsion composition any one of the 1 to 3, the wherein said essential oil containing terpenes is for being selected from the one or more of plants essential oils of the group be made up of tangerine oil, essential oils of herbs (herbal essential oil) and tree essential oil.

5th. the O/W micro emulsion composition any one of the 1 to 4, the wherein said essential oil containing terpenes is involved with the amount of 0.1 quality % to 4 quality %.

6th. a kind of product, described product comprises the O/W micro emulsion composition any one of the 1 to 5, and is selected from the group be made up of food and drink product, makeup, dental care products and perfume products (fragrance product).

The beneficial effect of the invention

O/W micro emulsion composition of the present invention has excellent stability in time, transparency and the dispersiveness in water.And micro emulsion composition of the present invention, does not need polyvalent alcohol such as isomerized liquid sugar, the strange taste do not caused by this class material, and be therefore applicable to being used in food and drink product etc.In addition, O/W micro emulsion composition of the present invention, relatively cheaply and do not need the special device or the operating process that utilize high pressure, vacuum or jet, has excellent treatment characteristic and is suitable for producing in enormous quantities.

Accompanying drawing is sketched

Fig. 1 shows and checks the result of the mixture ratio of component (A) and (B) on the impact of emulsified state and transparency.

Fig. 2 shows and checks the result of the mixture ratio of component (A) and (B) on the impact of emulsified state and transparency.

Fig. 3 shows and checks the result of the mixture ratio of component (A) and (C) on the impact of emulsified state and transparency.

Fig. 4 shows and checks the result of the mixture ratio of component (A) and (D) on the impact of emulsified state and transparency.

Fig. 5 shows and checks the result of the mixture ratio of component (A) and (D) on the impact of emulsified state and transparency.

Fig. 6 shows and checks the result of the amount of component (A) on the impact of emulsified state and transparency.

Embodiment describes

The present invention is described in detail following.

The term " micro emulsion " used in this manual refers to the emulsion sample dispersion system comprising two kinds of liquid, wherein micelle has about 100 nanometers or less diameter, and stable, the less visible ray of scattering on dispersion system thermodynamics, and seem transparent or semitransparent.

(A) containing the essential oil of terpenes

Micro emulsion composition of the present invention comprises the essential oil containing terpenes.Terpenes is not particularly limited, as long as it is recognized in perfume area is terpenes.The example comprises monoterpenes, sesquiterpenoids, diterpenes, sesterterpenoids, triterpenes, tetraterpenes and analogue.

The specific examples of monoterpenes comprises Geraniol, vernol, phantol, citral, geraniol, menthol, peppermint, myrcene, firpene, limonene, Terpineol 350, Karvon, ionone, camphor, isopropyltoluene (cymene), 2-baras camphor and analogue.The specific examples of sesquiterpenoids comprises Elemenum, cadinol, cadinene, farnesol, nerolidol, humulone (cloves), xantholine, cedrene, caryophyllene and analogue.The specific examples of diterpenes comprises Geraniol, phytol, sylvic acid, taxol and analogue.The specific examples of triterpenes comprises obacalactone, Tsubaki-saponin unit, lanosterol, Oleanolic Acid (livid purple Soviet Union, ginseng, Japanese Herba Swertiae bimaculatae (Swertia japonica), Portugal etc.), ursonic acid, MF59, what handkerchief alkane, betulinic acid and analogue.The specific examples of tetraterpenes comprises carotenoid, Lyeopene and analogue.

In these terpenes, monoterpenes and sesquiterpenoids are preferred; And firpene, limonene, peppermint etc. (monoterpenes), and nerolidol (sesquiterpene) is preferred.

Essential oil containing this terpenoid is not particularly limited.Such as, tangerine oil, essential oils of herbs and tree essential oil can be used suitably.The example of tangerine oil comprises grapefruit essential oil, lemon quintessence oil, bitter orange essential oil, orange essential oil, Bergamot, Ka Bosu fragrant citrus (kabosu) essential oil and analogue.The example of essential oils of herbs comprises Mentha arvensis L. syn.M.haplocalyxBrig essential oil, eucalyptus quintessence oil, Peppermint essential oil, Clary Sage (clary sage) essential oil, Rhizoma Alpiniae Officinarum essential oil, Basil Essential, spearmint essential oil, West Indian lemon grass essential oil, lemon verbena essential oil and analogue.The example of tree essential oil comprises Cypress ethereal oil, cdear essential oil, juniper berry essential oil, tea tree ethereal oil, pineapple essential oil, Petitgrain (petit grain) essential oil, eucalyptus quintessence oil and analogue.These essential oils can individually or with two or more combinationally use any according to the object used.Preferably use tangerine oil in one embodiment of the invention.

The terpenes of essential oil usually containing 70 quality % or more.The amount of the terpenes contained in the essential oil used in the present invention is not particularly limited.Such as, the amount of terpenes can be 70 quality % or more, and can be 80 quality % or more or 90 quality % or more.And the upper limit can be, such as 100 quality % or 98 quality %.

Can buy and use commercial available essential oil, maybe can use the essential oil obtained from plant by currently known methods.Such as, obtain from desired part such as leaf, fruit, bark, root, cane, pericarp, flower or the bud of plant by integrated processes suitably such as vapor distillation, oil/fat absorption, organic solvent extraction, supercritical fluid extraction and squeezing, or obtain essential oil from whole plant.Preferably by the essential oil that squeezing obtains, because it is not exposed to heat and is therefore less modified, and do not experience and cause unbalanced Evaporation between component.And it has excellent fragrance.

(B) ethanol

O/W micro emulsion composition of the present invention comprises ethanol.The ethanol that can use in the present invention is not particularly limited, as long as it is the rank usually used in perfume and field of food.Such as, the first step ethanol of 95% or higher, preferably 99% or higher is preferably used.Commercial available ethanol can be used without change.

(C) polyglycerol fatty acid ester

O/W micro emulsion composition of the present invention comprises polyglycerol fatty acid ester.Spendable polyglycerol fatty acid ester is not particularly limited in the present invention, as long as it is known in technical field of the present invention; But the polyglycerol fatty acid ester preferably used is for having by those of the structure represented with following formula (1):

Wherein R is the alkyl with 6 to 22 carbon atoms, preferably 8 to 16 carbon atoms; And n is 2 to 14 and preferably 8 to 12.The specific examples of this type of polyglycerol fatty acid ester comprises ten Tetradecanoic acid, monoester with 1,2,3-propanetriols, six Tetradecanoic acid, monoester with 1,2,3-propanetriols, DECAGLYCERYL MONOLAURATE, six glyceryl monolaurates, ten glycerol monopalmitate, six glycerol monopalmitate, SY-Glyster MSW 750, six Zerols, ten Monooctamoins, SY-Glyster MO 750 and analogue.These polyglycerol fatty acid esters can combinationally using individually or with two or more.Commercial available polyglycerol fatty acid ester can use without change.The polyglycerol fatty acid ester preferably used in the present invention is DECAGLYCERYL MONOLAURATE, SY-Glyster MSW 750 and SY-Glyster MO 750.

(D) polyoxyethylene sorbitan fatty acid ester

O/W micro emulsion composition of the present invention comprises polyoxyethylene sorbitan fatty acid ester.Polyoxyethylene sorbitan fatty acid ester is also referred to as sorbic ester, and has the structure that wherein polyoxyethylene is added into sorbitan-fatty acid ester.Spendable polyoxyethylene sorbitan fatty acid ester is not particularly limited in the present invention.Such as, preferred polyoxyethylene sorbitan fatty acid ester has the lipid acid containing 8 to 22 carbon atoms, preferably 12 to 18 carbon atoms, and have 3-60, preferably 5 to 30 the polyoxyethylene polymerization degree.The example of this type of polyoxyethylene sorbitan fatty acid ester comprises polyoxyethylene sorbitol acid anhydride list octanoate, Tween-20, Tween-60, polyoxyethylene sorbitan monooleate, TWEEN40, polyoxyethylene sorbitol acid anhydride sesquistearate, polyox-yethylene sorbitan tristearate, polyoxyethylene sorbitol acid anhydride isostearate, polyoxyethylene sorbitol acid anhydride sesquialter isostearate, polyoxyethylene sorbitol acid anhydride oleic acid ester, polyoxyethylene sorbitol acid anhydride sesquioleate, polyoxyethylene sorbitan trioleate and analogue.All these polyoxyethylene sorbitan fatty acid esters are all commercial available, and can use commerical prod without change.Preferred polyoxyethylene sorbitan fatty acid ester is Tween-20, Tween-60 and polyoxyethylene sorbitan monooleate.These polyoxyethylene sorbitan fatty acid esters can combinationally using individually or with two or more.

(E) other components

O/W micro emulsion composition of the present invention can only be made up of to (D) and water above component (A), but can comprise other component, if the excellent transparency of composition and stability not suppressed.The example of other component is comprising toner, thickening material, emulsifying agent, stablizer, sequestrant, other ester class, animal and plant extract, other tensio-active agent, polyvalent alcohol, carbohydrate, VITAMIN, amino acid, antioxidant, sanitas, ultraviolet inhibitor, pH adjusting agent and analogue.The present invention also comprises the embodiment that any one wherein do not comprised in these other components or more is planted.These other components are preferably water miscible.In some cases, preferred O/W micro emulsion composition of the present invention does not comprise silicone or triglyceride level, because it has adverse influence to emulsion.

(F) mixture ratio

Stable and in the emulsion of highly transparent in formation, O/W micro emulsion composition of the present invention preferably comprise in mass than the ethanol of the amount of large at least 2.5 times of the amount of component (A) as component (B).And, in further improvement transparency, the amount of ethanol than component (A) large more preferably at least 3 times, more preferably at least 3.5 times of amount, still more preferably at least 4 times, more preferably at least 5 times, more preferably at least 6 times, particularly preferably at least 7 times and most preferably at least 11 times further.When few at least 2.5 times of amount than component (A) of the amount of ethanol, stable emulsion cannot be obtained.And when using tree essential oil or essential oils of herbs, the amount of ethanol is preferably than large at least 3 times of the amount of essential oil.When using tangerine oil, the amount of ethanol is preferably than large at least 4 times of the amount of essential oil.Stable and in the emulsion of highly transparent, the upper limit of the amount of ethanol is not particularly limited in acquisition; But, because transparency and stability are no longer modified, the amount of ethanol can be set as the amount few at least 40 times, at least 30 times or at least 25 times than component (A).

Amount as the polyglycerol fatty acid ester of the component (C) in O/W micro emulsion composition of the present invention is not particularly limited, as long as can obtain stable emulsion; But reaching in high-clarity and excellent emulsified state, in mass the amount of component (C) preferably at least 3 times and more preferably at least 3.5 times larger than the amount of component (A).The upper limit of the amount of component (C) is not particularly limited; But because characteristic is no longer modified, the amount of component (C) is than few at least 20 times of the amount of component (A), preferably at least 15 times and more preferably at least 10 times in mass.

Amount as the polyoxyethylene sorbitan fatty acid ester of the component (D) in O/W micro emulsion composition of the present invention is not particularly limited, as long as can obtain stable emulsion; But reaching in high-clarity and excellent emulsified state, in mass larger than the amount of component (A) preferably at least 0.1 times of the amount of component (D), more preferably at least 0.2 times, more preferably at least 0.3 times and still more preferably at least 0.6 times.The upper limit of the amount of component (D) is not particularly limited; But because characteristic is no longer modified, the amount of component (D) is than few at least 3 times of the amount of component (A), preferably at least 1 times and more preferably at least 0.7 times in mass.

(G) measure

The amount of the essential oil containing terpenes as the component (A) in O/W micro emulsion composition of the present invention can be determined suitably, as long as stable emulsion can be obtained according to object; But the amount of component (A) is normally 0.01 quality % to 4 quality %, preferably 0.1 quality % to 2 quality % and more preferably 0.5 quality % to 2 quality %.

The amount of the component (B) in O/W micro emulsion composition of the present invention can be determined suitably according to the mixture ratio of the amount of component (A) and component (A).Such as, the lower limit of the amount of component (B) is 0.025 quality % or more, 0.03 quality % or more, 0.04 quality % or more, 0.05 quality % or more, 0.06 quality % or more, 0.07 quality % or more, 0.08 quality % or more, 0.1 quality % or more, 0.11 quality % or more, 0.45 quality % or more, 0.5 quality % or more, 0.6 quality % or more, 0.7 quality % or more, 0.8 quality % or more, 1 quality % or more, 1.1 quality % or more, 2.25 quality % or more, 2.5 quality % or more, 3 quality % or more, 3.5 quality % or more, 4 quality % or more, 5.5 quality % or more, 7.5 quality % or more, 10 quality % or more, or 12.5 quality % or more.The upper limit of the amount of component (B) is such as 60 quality % or less, 50 quality % or less, 40 quality % or less, 30 quality % or less, 25 quality % or less or 20 quality % or less.

Can according to the amount of component (A) and the amount determining the component (C) in O/W micro emulsion composition of the present invention about the mixture ratio of component (A) suitably.Such as, the lower limit of the amount of component (C) is 0.03 quality % or more, 0.035 quality % or more, 0.3 quality % or more, 0.35 quality % or more, 0.5 quality % or more, 1 quality % or more, 1.75 quality % or more, 3 quality % or more, 6 quality % or more or 7 quality % or more.The upper limit of the amount of component (C) is such as 40 quality % or less, 30 quality % or less, 20 quality % or less, 10 quality % or less or 9 quality % or less.

Can according to the amount of component (A) and the amount determining the component (D) in O/W micro emulsion composition of the present invention about the mixture ratio of component (A) suitably.Such as, the lower limit of the amount of component (D) is 0.001 quality % or more, 0.002 quality % or more, 0.003 quality % or more, 0.006 quality % or more, 0.01 quality % or more, 0.02 quality % or more, 0.03 quality % or more, 0.05 quality % or more, 0.06 quality % or more, 0.1 quality % or more, 0.15 quality % or more, 0.3 quality % or more, 0.4 quality % or more, 0.5 quality % or more or 1 quality % or more.The upper limit of the amount of component (D) is such as 12 quality % or less, 10 quality % or less, 8 quality % or less, 5 quality % or less, 4 quality % or less, 3.5 quality % or less, 2 quality % or less, 1.6 quality % or less, 1.4 quality % or less or 1.2 quality % or less.

O/W micro emulsion composition of the present invention preferably comprises component (A) to (D) with above-mentioned mixture ratio and/or amount.Remaining is water substantially, but if necessary, composition can comprise as other component as shown in above item (E).

Be not bound by theory, be thought as follows for the principle obtained owing to the excellent micro emulsion of structure of the present invention.Particularly, have have the polyoxyethylene sorbitan fatty acid ester of the hydrophilic segment of large radius skeleton central authorities there is hydrophobic chamber.When this type of polyoxyethylene sorbitan fatty acid ester being added into the solution of oil (solution of described oil is amphipathic make that it is dispersed by adding ethanol and polyglycerol fatty acid ester to make this solution), oil is wrapped in the central authorities of polyoxyethylene sorbitan fatty acid ester, thus forms stable micro emulsion.

(H) production method

Method by using routinely in technical field of the present invention utilizes above component to produce O/W micro emulsion composition of the present invention.Such as, by blending ingredients (A) to (D) and water, and obtain O/W micro emulsion composition of the present invention with homo-mixer suitable time that stirs the mixture.Do not limit the order of blending ingredients (A) to (D) especially.Such as, blending ingredients (A) and (B) are to prepare solution (1).Respectively, water is added into emulsifying agent (component (C) and (D)), and mixture is heated to fully dissolved emulsifier.When with homo-mixer stirring and circulation resultant, add solution (1).Stir speed (S.S.) is such as 500 to 5,000rpm.Easily can produce O/W micro emulsion of the present invention and not need to utilize high pressure homogenisers or other instruments.By the O/W micro emulsion composition of production being placed and being sealed in the O/W micro emulsion composition storing production in suitable container (such as tank or bottle).

(I) product

O/W micro emulsion composition of the present invention can be used for multiple product.The type of product is not particularly limited.The example of product comprises food and drink product, makeup, dental care products, perfume products and analogue.

The example of food and drink product comprises beverage such as iso-osmotic drink, nectar, soda pop, tea drink (such as black tea, oolong tea and green tea), fermented drink, coffee drinks, functional beverage, ardent spirits (liquor) (grape wine, whisky, brandy, Rum, gin, Liquor etc.), pure mellow wine, Sparkling wine, beer and other low-alcoholic beverage; And food, such as condiment, seasonings, retort food (retort food) and frozen confection.

The example of makeup comprises skin care cosmetics, such as skin cream, essence, emulsion and face cream; Lipstick, sun care preparations, cosmetic makeup, hair washing makeup, perfume makeup, UV nurse makeup, mouth care makeup, deodorization makeup, clean body makeup and analogue.

Product of the present invention (such as food and drink product) comprises emulsion composition of the present invention described above; But, if necessary, can add suitably normally with other component of often kind of Product mix.The amount of the emulsion composition of the present invention being added into often kind of product can be determined suitably according to the type of product, object etc.Such as, the amount of emulsion composition of the present invention can be 0.001 quality % to 10 quality % and preferably 0.01 quality % to 2 quality %.

Embodiment

Embodiment 1

By (A) containing the mixing of the essential oil of terpenes, (B) ethanol, (C) polyglycerol fatty acid ester, (D) polyoxyethylene sorbitan fatty acid ester and water, and mixture by homo-mixer with 5,000rpm stirs 20 minutes, thus generates O/W micro emulsion composition.The essential oil used is Mentha arvensis L. syn.M.haplocalyxBrig essential oil (PEPPERMINT DF 5%CUT) or Cypress ethereal oil (CYPRESS E_1016560).The polyglycerol fatty acid ester used is Poem J-0021 (being produced by Riken Vitamin Co., Ltd.).The polyoxyethylene sorbitol acid anhydride used is Emasol O-120V (polysorbate80 is produced by Kao Corporation).The amount of component (A), (C) and (D) is decided to be 2 quality %, 7 quality % and 1 quality % respectively.The amount of component (B) changes (table 1 and 2) in the scope of 1.5 to 6 times of the amount of component (A).Remaining is water.Allow the composition obtained at room temperature to leave standstill after one day, evaluate emulsified state and transparency according to judgement criteria shown in following table 3.

Table 1 uses the preparation of Mentha arvensis L. syn.M.haplocalyxBrig essential oil

(A)	(B)	(C)	(D)
				2.0	10.0	7.0	1.0
2.0	9.0	7.0	1.0
				2.0	8.0	7.0	1.0
2.0	7.0	7.0	1.0
				2.0	6.0	7.0	1.0
2.0	5.0	7.0	1.0
				2.0	4.0	7.0	1.0
2.0	3.0	7.0	1.0

(unit: quality %)

Table 2 uses the preparation of Cypress ethereal oil

(A)	(B)	(C)	(D)
				2.0	12.0	7.0	1.0
2.0	11.0	7.0	1.0
				2.0	10.0	7.0	1.0
2.0	9.0	7.0	1.0
				2.0	8.0	7.0	1.0
2.0	7.0	7.0	1.0
				2.0	6.0	7.0	1.0
2.0	5.0	7.0	1.0
				2.0	4.0	7.0	1.0

(unit: quality %)

Table 3

Mark	Transparency and emulsified state
		0	Non-emulsification, opaque and circularize at fluid surface
1	Emulsification but translucent and muddy
		2	Translucent, but not muddy
3	Opaque slightly, but almost limpid and transparent
		4	Limpid and transparent, and emulsification well

Fig. 1 shows evaluation result.The result of Fig. 1 discloses, and when large at least 2.5 times of amount than essential oil (A) of the amount of ethanol (B), the transparency of composition and emulsified state are increased significantly.

Embodiment 2

To produce O/W micro emulsion composition with identical mode in embodiment 1, except using grapefruit essential oil (Grapefruit E_0020345, by V.MANE FILS Co., Ltd. produce) as component (A), and the amount of ethanol (B) is in the range (table 4) of 0 to 10 times of the amount of component (A).As a comparison, use the grapefruit essential oil (N.1999M_0050991 Grapefruit cristalia, is produced by V.MANE FILS Co., Ltd.) without terpenes to carry out identical test.With the composition obtained with each self-evaluation of identical mode in embodiment 1.Fig. 2 shows result.The result of Fig. 2 confirms even when using grapefruit essential oil, by the micro emulsion composition utilizing preparation of the present invention to obtain highly transparent.

Table 4 uses the preparation of grapefruit essential oil

(A)	(B)	(C)	(D)
				2.0	0.0	7.0	1.0
2.0	2.5	7.0	1.0
				2.0	8.0	7.0	1.0
2.0	8.5	7.0	1.0
				2.0	9.0	7.0	1.0
2.0	9.5	7.0	1.0
				2.0	17.5	7.0	1.0
2.0	20.0	7.0	1.0

(unit: quality %)

Embodiment 3

To produce with identical mode in embodiment 1 and to evaluate O/W micro emulsion composition, except using Ka Bosu fragrant citrus essential oil, Bergamot (BERGAMOTE REGGIO EDIBLEE_MFJ1038) or orange essential oil (ORANGE BLOOD OIL F_O15259) as component (A).By using Ka Bosu fragrant citrus essential oil, Bergamot and the result of orange essential oil acquisition and coming to the same thing in embodiment 1.That is, the O/W micro emulsion composition by utilizing preparation of the present invention to obtain highly transparent.

Embodiment 4

To produce O/W micro emulsion composition with identical mode in embodiment 1, except the amount of component (A), (B) and (D) is determined respectively to 2 quality %, 10 quality % and 1 quality %, and the amount of component (C) changes (table 5) in the scope of 0 to 10 times of the amount of component (A).Use without the grapefruit essential oil of terpenes to be used as comparison object with the composition that identical mode is in embodiment 1 produced.Fig. 3 shows to evaluate the result of the composition of acquisition with identical mode in embodiment 1.The result of Fig. 3 discloses, and by adding the polyglycerol fatty acid ester (C) of the amount of large at least 3 times of the amount than the essential oil (A) containing terpenes, obtains micro emulsion composition transparent more to heavens.

Table 5 uses grapefruit essential oil and changes the preparation of the mixture ratio of component (C)

(A)	(B)	(C)	(D)
				2.0	10.0	0.0	1.0
2.0	10.0	1.0	1.0
				2.0	10.0	2.0	1.0
2.0	10.0	3.0	1.0
				2.0	10.0	4.0	1.0
2.0	10.0	5.0	1.0
				2.0	10.0	6.0	1.0
2.0	10.0	7.0	1.0
				2.0	10.0	8.0	1.0
2.0	10.0	9.0	1.0
				2.0	10.0	10.0	1.0

(unit: quality %)

Embodiment 5

To produce O/W micro emulsion composition with identical mode in embodiment 1, except the amount of component (A), (B) and (C) is determined respectively to 2 quality %, 10 quality % and 7 quality %, and the amount of component (D) changes (table 6) in the scope of 0 to 1 times of the amount of component (A).Use without the grapefruit essential oil of terpenes to be used as comparison object with the composition that identical mode is in embodiment 1 produced.Fig. 4 shows to evaluate the result of the composition of acquisition with identical mode in embodiment 1.The result of Fig. 4 discloses, and by adding the polyoxyethylene sorbitan fatty acid ester (D) of the amount of large at least 0.1 times of the amount than the essential oil (A) containing terpenes, obtains micro emulsion composition transparent more to heavens.

Table 6 uses grapefruit essential oil and changes the preparation of the mixture ratio of component (D)

(A)	(B)	(C)	(D)
				2.0	10.0	7.0	0.0
2.0	10.0	7.0	0.2
				2.0	10.0	7.0	0.4
2.0	10.0	7.0	0.6
				2.0	10.0	7.0	0.8
2.0	10.0	7.0	1.0
				2.0	10.0	7.0	1.2
2.0	10.0	7.0	1.4
				2.0	10.0	7.0	1.6
2.0	10.0	7.0	1.8
				2.0	10.0	7.0	2.0

(unit: quality %)

Embodiment 6

Carry out the test identical with embodiment 5, except using polysorbate60 or polysorbate20 as polyoxyethylene sorbitan fatty acid ester (D).Fig. 5 shows result.The result shown in Figure 5 discloses, even when using polysorbate60 or polysorbate20, by adding the polyglycerol fatty acid ester (C) of the amount of large at least 0.1 times of the amount than the essential oil (A) containing terpenes, obtain micro emulsion composition transparent more to heavens.

Embodiment 7

To produce O/W micro emulsion composition with identical mode in embodiment 1, except the amount of component (B), (C) and (D) is determined respectively to 10 quality %, 7 quality % and 1 quality %, and the amount of component (A) changes (table 7) in the scope of 0.5 quality % to 4 quality %.Use without the grapefruit essential oil of terpenes to be used as comparison object with the composition that identical mode is in embodiment 1 produced.Fig. 6 shows to evaluate the result of the composition of acquisition with identical mode in embodiment 1.The result of Fig. 6 discloses, and when the amount of component (A) reaches 2 quality %, obtains micro emulsion composition transparent to heavens by the preparation of this embodiment.

Table 7 changes the preparation of the amount of component (A)

(A)	(B)	(C)	(D)
				0.5	10.0	7.0	1.0
1.0	10.0	7.0	1.0
				1.5	10.0	7.0	1.0
2.0	10.0	7.0	1.0
				2.5	10.0	7.0	1.0
3.0	10.0	7.0	1.0
				3.5	10.0	7.0	1.0
4.0	10.0	7.0	1.0

(unit: quality %)

Embodiment 8

To produce O/W micro emulsion composition with identical mode in embodiment 1, except using blood orange essential oil as component (A).Result confirms, by the micro emulsion composition utilizing preparation of the present invention to obtain highly transparent.

Claims

1. an O/W micro emulsion composition, comprises:

(A) containing the essential oil of terpenes,

(B) ethanol,

(C) polyglycerol fatty acid ester, and

(D) polyoxyethylene sorbitan fatty acid ester;

2. O/W micro emulsion composition according to claim 1, wherein said O/W micro emulsion composition has (A) of 1:3 to 20 in mass than (C) ratio.

3. O/W micro emulsion composition according to claim 1 and 2, wherein said O/W micro emulsion composition has (A) of 1:0.1 to 3 in mass than (D) ratio.

4. O/W micro emulsion composition according to any one of claim 1 to 3, the wherein said essential oil containing terpenes is the one or more of plants essential oils being selected from the group be made up of tangerine oil, essential oils of herbs and tree essential oil.

5. O/W micro emulsion composition according to any one of claim 1 to 4, the wherein said essential oil containing terpenes is involved with the amount of 0.1 quality % to 4 quality %.

6. a product, described product comprises O/W micro emulsion composition according to any one of claim 1 to 5, and is selected from the group be made up of food and drink product, makeup, dental care products and perfume products.