CN1049353C - Chinese medicinal preparation for curing rheumatism and rheumatoid disease and its prepn. method - Google Patents
Chinese medicinal preparation for curing rheumatism and rheumatoid disease and its prepn. method Download PDFInfo
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- CN1049353C CN1049353C CN97114453A CN97114453A CN1049353C CN 1049353 C CN1049353 C CN 1049353C CN 97114453 A CN97114453 A CN 97114453A CN 97114453 A CN97114453 A CN 97114453A CN 1049353 C CN1049353 C CN 1049353C
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Abstract
The present invention relates to Chinese patent medicine for treating rheumatic diseases and rheumatoid diseases and a preparation method thereof. The Chinese patent medicine is prepared from traditional Chinese medicine as raw materials. The present invention is characterized in that the Chinese patent medicine comprises Chinese herbal medicine comprising the following components as raw materials: silky ant, curculigo rhizome, parched white mustard seed, black-tail snake, gastrodia tuber, Chinese ephedra, cinnamon, deglued antler, parched pangolin scale, angelica, notoginseng, keel and dried ginger. The present invention has the advantages of no toxic and side effect, small dosage and short treatment cycle. The effective rate of the present invention can reach 97%. The present invention can make the immunity of patients largely improved, and can be widely applied to treating various kinds of rheumatic diseases and rheumatoid diseases.
Description
The present invention relates to a kind of treatment rheumatism, rheumatoid medicine, is the Chinese patent medicine of raw material system with Chinese medicine specifically, the invention still further relates to the preparation method of this medicine.
Rheumatism, rheumatoid disease are present a kind of common diseases, adopt the medicine of antiinflammatory town disease to treat usually.This class medicine has ibuprofen, chlofenamic acid, cortisone, Radix Tripterygii Wilfordii etc., but the bigger problem of this class medicine ubiquity toxic side effect.With the Radix Tripterygii Wilfordii is example: though it also is a kind of Chinese medicine preparation, and have sure antiinflammatory, analgesia, immunosuppressive action, it all has tangible detrimental effect to patient's gastrointestinal tract, mucocutaneous, conscience, kidney and reproductive system.And common rheumatism or rheumatoid patient's the course of disease is all longer, need take medicine for a long time, and obviously the toxic and side effects of this class medicine is bigger, when taking this class medicine for a long time, can cause new injury to patient again undoubtedly, produce new misery, and can not reach ideal therapeutic effect.Some medicine also contains more hormone composition, if infection such as mycete, virus, tuberculosis very easily take place life-time service, brings new misery to patient.
Also occur employing " ant preparation " treatment rheumatism, rheumatoid in recent years, and obtained some progress and curative effect.Recorded and narrated " spirit of Formica fusca rheumatoid " Chinese medicine preparation as in No. the 93110592.7th, the Chinese patent, it is to be " monarch " medicine with Formica fusca, and insecticide, reptile of being equipped with other etc. are used as medicine, main treatment rheumatoid arthritis, this preparation makes that this medicine price is higher because the raw material of Chinese medicine that adopts is all somewhat expensive.And this medicine is powder, and windage is big when oral, and inconvenient, and this medicine in use requires, and taking dose is big, the cycle of taking is also very long, and therefore general patient is difficult to bear.
With regard to the raw material of Chinese medicine processing of such medicine, in the prior art, for go into medicinal Formica fusca, the Serpentis class all adopts high-temperature oven drying method to carry out dried, and this method makes the wherein active ingredient (albumen, formic acid) of Formica fusca, Serpentis class by considerable damage, finally cause having only heavy dose of medication just can reach therapeutic effect, thereby caused the medication cycle long, problems such as drug cost increase.
One of purpose of the present invention is utilize to change reagent combination, thus provide a kind of nontoxic, have no side effect, medication economy, therapeutic effect better treats rheumatism, rheumatoid Chinese medicine preparation, and makes said preparation have the effect that strengthens the patient immune function.
Another object of the present invention provides and a kind ofly guarantees the medicine active ingredient, thereby guarantees the preparation method of the said preparation of therapeutic effect.
The objective of the invention is to realize by following scheme:
A kind of treatment rheumatism, rheumatoid Chinese medicine preparation is characterized in that it is the medicament of being made by the following weight proportion raw material:
Formica fusca 25-37% Rhizoma Curculiginis 5-8% Semen Sinapis Albae (parched) 8-10%
Zaocys 8-15% Rhizoma Gastrodiae 3-8% Herba Ephedrae 3-8%
Cortex Cinnamomi 3-5% Cornu Cervi Degelatinatum 8-15% stir-baked SQUAMA MANITIS 3-8%
Radix Angelicae Sinensis 8-10% Radix Notoginseng 3-8% Os Draconis 8-15%
Rhizoma Zingiberis 3-5%
Method with the medication preparation Chinese medicine preparation of the present invention of above-mentioned each weight composition is:
1, get Rhizoma Gastrodiae, Radix Notoginseng after rinsing, drying, first coarse powder changes 100 mesh sieve fine powders again, and it is standby to collect fine powder.
2, get Os Draconis, Rhizoma Curculiginis, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Zingiberis, Semen Sinapis Albae (parched) mixing back pulverizing, and it is standby to cross 100 mesh sieves.
3, with Formica fusca, Zaocys places in the material disc, puts into vacuum drying oven, and under 80 ℃ temperature dry 10-12 hour, and with Formica fusca powder process, it is standby to cross 100 mesh sieves.
4, Zaocys vacuum drying treatment and cutting, the Cornu Cervi Degelatinatum that smashes, these three kinds of animal drugs of stir-baked SQUAMA MANITIS are mixed the back coarse powder, cross 100 mesh sieve fine powders then, collect standby.
5, will after mixing, all raw materials by weight of above-mentioned PROCESS FOR TREATMENT cross 100 mesh sieve fine powders.
6, get the 5-10% dried starch that weight is above mixed weight raw material in addition,, divide the bag of packing into then with above-mentioned mixed powder mix homogeneously.
7, the medicated powder that will go into bag carries out irradiation sterilization.
8, branch is encapsulated.
Its body of the Formica fusca that is adopted among the present invention contains the acid of high-octane monomer mosquito, full ant body contains protein up to 40-67%, the free amino acid and multivitamin and the trace element that in the ant body, also contain the human body needs, and the fat content of mosquito body is extremely low, but contain profuse zinc, the full ant body of per kilogram contains zinc and can reach the 110-120 milligram.The Rhizoma Gastrodiae that uses among the present invention, Herba Ephedrae have the effect that temperature is separated YIN-cold, timid diffusing rheumatism, and stir-baked SQUAMA MANITIS, Radix Notoginseng can play the effect that the collateral dredging detumescence relieves the pain; Add Cortex Cinnamomi, Rhizoma Zingiberis can disperse wind-cold damp pathogen in middle Jiao, wet in cold expelling fiery supporing yang with benefit guarantor in the gate of vitality, to reach the purpose that promoting the flow of QI-blood by warming the meridian, cold expelling relieve the pain.But with Semen Sinapis Albae, Cornu Cervi Degelatinatum, Rhizoma Curculiginis kidney-replenishing wind-damp dispelling, separate the podomere contracture, the bone and muscle strengthening migratory arthralgia relieves the pain.Radix Angelicae Sinensis, Os Draconis share in order to healthy energy and hold up this, the Zaocys expelling wind and removing dampness, search and pick the network heresy, can clear up swollen painful.By above prescription as can be known, the present invention does not have the taboo of " anti-fear ".
The present invention shows that through clinical practice following advantage is arranged:
The present invention has no side effect, and has adopted the combination of animal drugs and plant amedica, makes the various composition mutual-assistances in the patent medicine, and reaches the therapeutic purposes of eliminating pathogenic factor for supporting vital QI.The present invention also has antiinflammatory, calmness, wide spectrum immunopotentiation.Dosage of the present invention is suitable, treatment cycle short, and can reach the positive effect of treatment in the short period, and makes patient's immunity that bigger enhancing be arranged.
Treatment effect of the present invention is:
Clinical use patient stochastic sampling 30 examples.20 of wherein women surnames, 10 of male, at minimum 22 years old of age, maximum 76 years old, the patient who is diagnosed as rheumatoid arthritis was 23 examples, 4 examples of rheumatic arthritis, other rheumatism 3 examples.Three months is a treatment stage, 30 days the course of treatment, in middle drug withdrawal 1-2 week, begins second course of treatment again, prove through medication: reaching recent control has 8 examples, accounts for 26.6%, and 16 examples that have of remarkable result are arranged, and accounts for 53.3%, resultful 5 examples account for 16.7%, and invalid have 1 example, accounts for 3%.Its total effective rate reaches 97%.
Embodiment:
Take by weighing raw material by following proportioning: Formica fusca is selected Polyhachis vicina Roger for use.
Polyhachis vicina Roger: 25 kilograms, 5 kilograms of Rhizoma Curculiginises, 8 kilograms of Semen Sinapis Albae (parched), 8 kilograms of Zaocyss, 3 kilograms in Rhizoma Gastrodiae, 3 kilograms in Herba Ephedrae, 3 kilograms of Cortex Cinnamomis, 8 kilograms of Cornu Cervi Degelatinatums, 3 kilograms of Radix Notoginseng, 8 kilograms of Os Draconis, 3 kilograms of stir-baked SQUAMA MANITISs, 8 kilograms of Radix Angelicae Sinensis, 3 kilograms of Rhizoma Zingiberiss.
At first Polyhachis vicina Roger and Zaocys being placed thing is dish, puts into vacuum drier, under 80 ℃ temperature dry 10 hours; With Rhizoma Gastrodiae, Radix Notoginseng is after rinsing, drying, and first coarse powder after 100 mesh sieve fine powders, is collected standby; Get Os Draconis, Rhizoma Curculiginis, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Zingiberis, Semen Sinapis Albae (parched) mixing back pulverizing, and cross 100 mesh sieves, standby.Zaocys, stir-baked SQUAMA MANITIS, Cornu Cervi Degelatinatum mix the back to be pulverized, and crosses 100 mesh sieves, standby.Polyhachis vicina Roger is made powdery, and fully mix,, and in mixed medicated powder, add 5 kilograms dried starch, in the bag of packing into, and carry out irradiation sterilization after 100 mesh sieves with the above-mentioned various Chinese medicinal ingredients of handling well.With the loading amount of medicated powder of the present invention, make capsule at last by 0.25 gram/grain.Be mixed into dried starch in medicated powder, purpose has two, and the one, contained animal oil in the adsorbable medicated powder, two ratios of technology can guarantee the glue capsule time are easier to carry out.
Usage of the present utility model:
When the traditional Chinese medical science is diagnosed as " anemofrigid-damp arthralgia ", " cold Sheng type ", oral three times of every day, each 4-6 grain, every capsules explosive payload is 0.3 gram, and 30 days is a course of treatment, and 1-2 week is withdrawn in the centre, begins to obey second course of treatment again, and taking three months is a stage.After stage finishes, can reduce dosage according to patient's recovery situation, general every day oral secondary, each three get final product.
Claims (2)
1, a kind of treatment rheumatism, rheumatoid Chinese medicine preparation is characterized in that it is the medicament of being made by following materials of weight proportions:
Formica fusca 25-37% Rhizoma Curculiginis 5-8% Semen Sinapis Albae (parched) 8-10%
Zaocys 8-15% Rhizoma Gastrodiae 3-8% Herba Ephedrae 3-8%
Cortex Cinnamomi 3-5% Cornu Cervi Degelatinatum 8-15% stir-baked SQUAMA MANITIS 3-8%
Radix Angelicae Sinensis 8-10% Radix Notoginseng 3-8% Os Draconis 8-15%
Rhizoma Zingiberis 3-5%
2, the treatment rheumatism described in claim 1, rheumatoid Chinese medicine preparation is characterized in that it is the medicament that is prepared from by following method:
A, get Rhizoma Gastrodiae, Radix Notoginseng after rinsing, drying, first coarse powder changes 100 mesh sieve fine powders again, and it is standby to collect fine powder.
B, get Os Draconis, Rhizoma Curculiginis, Cortex Cinnamomi, Radix Angelicae Sinensis, Rhizoma Zingiberis, Semen Sinapis Albae (parched) and mix the back by described percentage by weight and pulverize, and it is standby to cross 100 mesh sieves.
C, with Formica fusca, Zaocys places in the material disc, puts into vacuum drying oven, under 80 ℃ temperature dry 10-12 hour, and with Formica fusca powder process.
D, Zaocys will be vacuum drying treatment and cutting, the Cornu Cervi Degelatinatum that smashes, these three kinds of animal drugs of stir-baked SQUAMA MANITIS are mixed back coarse powder, cross 100 mesh sieve fine powders then, collect standby.
E, will after mixing, all raw materials by weight of above-mentioned PROCESS FOR TREATMENT cross 100 mesh sieve fine powders.
F, in the described fine powder behind the mix homogeneously, add the dried starch of 5-10% of institute's mixed powder of weight,, divide the bag of packing into then with above-mentioned mixed powder mix homogeneously.
G, will go into the bag medicated powder carry out irradiation sterilization.
B, divide encapsulated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97114453A CN1049353C (en) | 1997-07-30 | 1997-07-30 | Chinese medicinal preparation for curing rheumatism and rheumatoid disease and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97114453A CN1049353C (en) | 1997-07-30 | 1997-07-30 | Chinese medicinal preparation for curing rheumatism and rheumatoid disease and its prepn. method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1173365A CN1173365A (en) | 1998-02-18 |
| CN1049353C true CN1049353C (en) | 2000-02-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN97114453A Expired - Fee Related CN1049353C (en) | 1997-07-30 | 1997-07-30 | Chinese medicinal preparation for curing rheumatism and rheumatoid disease and its prepn. method |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0983766A1 (en) * | 1999-01-20 | 2000-03-08 | Norbert A. Gschwend | A pharmaceutical composition for the treatment of rheumatoid disorders comprising sulphur, mustard seeds and a copper salt |
| CN100355441C (en) * | 2005-08-15 | 2007-12-19 | 潘忠清 | Medicine for treating rheumatic and rheumatoid diseases |
| CN101406688B (en) * | 2008-11-28 | 2010-12-22 | 魏玉玲 | Compound formulation for treating rheumatic arthritis and rheumatoid arthritis |
| CN101804098B (en) * | 2010-05-24 | 2014-04-16 | 三峡大学第一临床医学院 | Compound cornu cervi degelatinatum preparation as well as preparation method and application thereof |
-
1997
- 1997-07-30 CN CN97114453A patent/CN1049353C/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 《江苏中医》1989,10(2) 1989.2.28 郑春雷等，顽痹合剂治疗类风湿性关节炎96例临床观察-附对照组3 * |
| 《江苏中医》1989,10(2) 1989.2.28 郑春雷等，顽痹合剂治疗类风湿性关节炎96例临床观察-附对照组3;《辽宁中医杂志》1995,22(7) 1995.7.30 聂志伟等，蚂蚁制剂治疗类风湿性关节炎的疗效对比观察 * |
| 《辽宁中医杂志》1995,22(7) 1995.7.30 聂志伟等，蚂蚁制剂治疗类风湿性关节炎的疗效对比观察 * |
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| Publication number | Publication date |
|---|---|
| CN1173365A (en) | 1998-02-18 |
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