CN104932087A - Integrated optical coherent detection probe - Google Patents

Integrated optical coherent detection probe Download PDF

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Publication number
CN104932087A
CN104932087A CN201510249903.8A CN201510249903A CN104932087A CN 104932087 A CN104932087 A CN 104932087A CN 201510249903 A CN201510249903 A CN 201510249903A CN 104932087 A CN104932087 A CN 104932087A
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CN
China
Prior art keywords
imaging lens
sleeve pipe
optical fiber
detection probe
light beam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510249903.8A
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Chinese (zh)
Inventor
苏善行
侯捷
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O Puddo Viv (cayman) Holding Ltd
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O Puddo Viv (cayman) Holding Ltd
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Application filed by O Puddo Viv (cayman) Holding Ltd filed Critical O Puddo Viv (cayman) Holding Ltd
Priority to CN201510249903.8A priority Critical patent/CN104932087A/en
Publication of CN104932087A publication Critical patent/CN104932087A/en
Pending legal-status Critical Current

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Abstract

The invention provides an integrated optical coherent detection probe, which comprises a bushing, an imaging lens plated with a reflecting layer, a light beam emitting system, an optical fiber base pin used for fixing the light beam emitting system, and a UV epoxy adhesive filled in gaps between the light beam emitting system and the bushing, and between the optical fiber base pin and the bushing. The imaging lens is in the form of an off-axis concave spherical mirror or an off-axis convex spherical mirror, wherein the central axis of the imaging lens is at an included angle relative to the central axis of the bushing. The light beam emitting system is used for guiding a light beam sent out by a light source. The light beam emitting system comprises a fiber core, an optical fiber coating layer and a light source. The central axis of the fiber core coincides with the central axis of the bushing. The overall internal optical path of the integrated optical coherent detection probe has fewer optical end surfaces, so that the interference of the feedback light on weak detection signals can be avoided entirely. An air layer is arranged between the imaging lens and the fiber core. The fiber core can move within the air layer. Therefore, different investigation depths can be enabled only through changing the distance between the end surface of an optical fiber and the imaging lens.

Description

Integrated optical coherence detection probe
Technical field
The present invention relates to technical field of medical instruments, particularly relate to one and can be used for the integrated optical coherence detection probe that optical coherence detects (OCT).
Background technology
Along with the reach of science, in medical science and biology, successively there is various Image-forming instrument, optical image technology becomes the comparatively ideal technology that compares, wherein topmost representative is Optical coherence tomography (optical coherence tomography), hereinafter referred to as OCT.Its advantage is: to utilize the infrared light of human zero damage as light source (being generally 830nm or 1310nm), utilize the principle of door coherence time to realize chromatography, can realize noncontact, radiationless, high resolving power real time imagery and in body biopsy.It is mainly used in ophthalmology, skin, dentistry, cardiovascular, respiratory tract and intestines and stomach, early-stage cancer detection etc.In recent years, OCT is not only widely used in the medical domains such as artery, vein, lung airway due to the microminiaturization of interior pry head, can also be used for the micropore of the detection such as femto-second laser processing of various narrow space.
Single-mode fiber, coreless fiber, self-focusing optical fiber and 90 ° of catoptrons need be combined for spying upon head in OCT in prior art.General optical system return loss is about 60dB, but the signal to noise ratio (S/N ratio) of OCT system can reach more than 100dB, and the reflected light that each end face therefore in light path produces still can be interfered mutually, forms interference ring, has a strong impact on the quality of image.And due to optics end face many, when connecting multiple end face, technique is more complicated, and manufacture difficulty is large, and production cost is high.
In order to solve the technical matters of interference ring, interior pry head is also had to use the combination of single-mode fiber and globe lens.But shortcoming is that the diameter of globe lens is comparatively large, and the blood vessel less to some diameter can not be suitable for, and generally only can be applicable to external skin detection.In addition, the interior pry head operating distance of this combination is less than 1mm, only can detect along shaft axis of optic fibre direction signal, cannot blood vessel, natural cavity in detection imaging body.
Summary of the invention
The object of the present invention is to provide simple, easy for installation can the avoiding interference ring, obtain high resolving power pattern and be applicable to the integrated optical coherence detection probe of different investigation depth of a kind of structure.
A kind of integrated optical coherence detection probe, comprises: a sleeve pipe; One imaging lens being coated with reflection horizon; One beam delivery system; One optical fiber contact pins being used for fixing beam delivery system; And for filling between beam delivery system and sleeve pipe, the ultraviolet epoxy glue in the gap of optical fiber contact pins and sleeve pipe;
Described sleeve pipe has a relative front end, rear end;
Described imaging lens is arranged on the front end of sleeve pipe, and select from axle concave spherical mirror or from crown of roll spherical mirror, its radius-of-curvature is 0.2 ~ 3mm; The scope that the central shaft of imaging lens and the central shaft of sleeve pipe form angle is 25 ~ 65 degree;
Described beam delivery system is arranged on the rear end of sleeve pipe, is used for guiding the light beam that sends of light source, and it comprises fibre core, optical fiber coating and light source, and wherein the central shaft of fibre core overlaps with the central shaft of sleeve pipe; Optical fiber coating is coated in the outside surface of fibre core, is used for protecting fibre core;
Described optical fiber contact pins is arranged on the position of inside pipe casing near rear end, and core segment stretches in optical fiber contact pins.
Integrated optical coherence detection probe provided by the invention, has following beneficial effect:
1, whole probe only has two, the reflection horizon optics end face of fiber end face, imaging lens, and return light can be avoided completely to the interference of small and weak detectable signal.
2, operating distance is longer, and to visible ray, the low scattering of near infrared light, little spherical aberration, realize focused light spot and be less than 15 microns, desirable securing satisfactory grades distinguishes rate interference pattern.
3, only need to change the distance between fiber end face to imaging lens, different investigation depths can be realized.
Accompanying drawing explanation
The structural representation of integrated optical coherence detection probe in Fig. 1 embodiment of the present invention 1.
The structural representation of integrated optical coherence detection probe in Fig. 2 embodiment of the present invention 2.
The schematic diagram of the imaging lens in Fig. 3 embodiment of the present invention 2.
The fundamental diagram of Fig. 4 integrated optical coherence detection probe of the present invention.
Embodiment
A kind of integrated optical coherence detection probe, comprises: a sleeve pipe 10; One imaging lens 20; One beam delivery system 30; One optical fiber contact pins 40 being used for fixing beam delivery system; Ultraviolet epoxy glue 50 for filling between beam delivery system 30 and sleeve pipe 10, optical fiber contact pins 40 and the gap of sleeve pipe 10, play the effect of fixed beam emission coefficient 30, optical fiber contact pins 40 and sleeve pipe 10.
Described sleeve pipe 10 has a central shaft AO axle and relative front end 11, rear end 12, and sleeve pipe 10 can select the optical material consistent with imaging lens 20 refractive index, as quartz; Or the lighttight material such as metal.
Near the place of front end 11 on the central shaft AO axle that described imaging lens 20 is arranged on sleeve pipe 10, the central shaft AO axle of its central axis AC axle and sleeve pipe 10 forms an angle theta, and angle theta gets 25 ~ 65 degree.Imaging lens 20 can be selected from axle concave spherical mirror or from crown of roll spherical mirror, and the surface of imaging lens 20 is coated with reflection horizon 21S.Optional 0.2 ~ the 3mm of radius of curvature R of imaging lens 20.
Described beam delivery system 30 is arranged on the rear end 12 of sleeve pipe 10, it comprises fibre core 31, optical fiber coating 32 and light source 33, wherein the central shaft of fibre core 31 overlaps with the central shaft AO axle of sleeve, is used for guiding the light beam that sends of light source 33, and there is a fiber end face 31S its one end near imaging lens 20; Optical fiber coating 32 is coated in the outside surface of fibre core 31, is used for protecting fibre core 31.
Described optical fiber contact pins 40 is arranged on the inner place near rear end 12 of sleeve pipe 10, and fibre core 31 part in described beam delivery system 30 extend in optical fiber contact pins 40.The effect of optical fiber contact pins 40 is fixed by fibre core 31, and the central shaft of fibre core 31 is overlapped with the central shaft AO axle of sleeve, keeps the stable of beam emissions.
Can also have an air layer 60 between described imaging lens 20 and beam delivery system 30, fibre core 31 can move, to meet different investigation depths in this air layer 60.
Below in conjunction with embodiment, the present invention is described further.
Integrated optical coherence detection probe as shown in Figure 1, the lighttight materials such as metal selected by described sleeve pipe 10; An aperture 13 is opened in the side that sleeve 10 converges near front end 11 and imaging lens 20 reflected light, is used for printing opacity.Described imaging lens 20 is selected from axle concave spherical mirror, and have an air layer 60 between described imaging lens 20 and fibre core 31, fibre core 31 can move in this air layer 60, to change the distance S1 of fiber end face 31S to imaging lens 20 axle center, and then changes the distance S2 of convergent point C to the first central shaft AO axle.When the radius of curvature R of imaging lens 20 selects 0.2 ~ 2.8mm, by the distance S1 of adjustment fiber end face 31S to imaging lens 20 axle center, the operating distance S2 of integrated optical coherence detection probe can change between 1 ~ 5mm.Such as, when the radius of curvature R of imaging lens 20 is 0.6mm, adjustment S1 is that 0.9mm, S2 can be greater than 2mm.Namely not only operating distance is long for integrated optical coherence detection probe, can also meet different investigation depths.
Integrated optical coherence detection probe as shown in Figures 2 and 3, the integrated optics of described imaging lens 20 is from crown of roll spherical mirror, and it has a radius of curvature R to be imaging lens front end 21 and a columniform imaging lens rear end 22 of the convex spherical of 0.2 ~ 3mm.The convex spherical of described imaging lens front end 21 is coated with reflection horizon 21S.Described imaging lens rear end 22 part stretches into sleeve 10.The optical material consistent with imaging lens 20 refractive index selected by described sleeve pipe 10, as quartz.Integrated optical coherence detection probe now only has reflection horizon 21S two optics end faces of fiber end face 31S and imaging lens 20, return light can be avoided completely to the interference of small and weak detectable signal, simultaneously to visible ray, the low scattering of near infrared light, little spherical aberration, realize focused light spot and be less than 15 microns, desirable securing satisfactory grades distinguishes rate interference pattern.Also can have an air layer 60 between described imaging lens rear end 22 and fibre core 31, fibre core 31 can move, to meet different investigation depths in this air layer 60.
As shown in Figure 4, the principle of work of this integrated optical coherence detection probe is as follows:
Light source 33 sends visible light beam or infrared beam is input in fibre core 31, and light beam radiate with the form of Gaussian beam from the fiber end face 31S of fibre core 31.When on the reflection horizon 21S that radiant light is injected into imaging lens 20, light beam can by turnover 90 degree, and again converges on a very little some C.Fiber end face 31S is S1 to the distance in imaging lens 20 axle center, and the distance of convergent point C to AO axle is S2.S2 is the operating distance of integrated optical coherence detection probe.When fiber end face 31S to imaging lens 20 axle center distance S1 change time, the distance S2 of convergent point C to AO axle also can change thereupon.Different investigation depths can be realized thus.
Integrated optical coherence detection probe provided by the invention, structure is simple, be easy to produce and install.Only there are reflection horizon 21S two optics end faces of fiber end face 31S, imaging lens 20 in the light path of whole probe, return light can be avoided completely to the interference of small and weak detectable signal; Operating distance is long, and to visible ray, the low scattering of near infrared light, little spherical aberration, realize focused light spot and be less than 15 microns, convenient operation person obtains high resolving power interference pattern; Air layer 60 is set between imaging lens 20 and fibre core 31, the distance between fiber end face 31S to imaging lens 20 can be changed easily, different investigation depths can be realized.
The foregoing is only embodiments of the invention, not thereby limit the scope of the claims of the present invention.Every utilize description of the present invention to do equivalent structure or the conversion of equivalent flow process, or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.

Claims (4)

1. an integrated optical coherence detection probe, comprises: a sleeve pipe; One imaging lens being coated with reflection horizon; One beam delivery system; One optical fiber contact pins being used for fixing beam delivery system; And for filling between beam delivery system and sleeve pipe, the ultraviolet epoxy glue in the gap of optical fiber contact pins and sleeve pipe;
Described sleeve pipe has a relative front end, rear end;
Described imaging lens is arranged on the front end of sleeve pipe, and select from axle concave spherical mirror or from crown of roll spherical mirror, its radius-of-curvature is 0.2 ~ 3mm; The scope that the central shaft of imaging lens and the central shaft of sleeve pipe form angle is 25 ~ 65 degree;
Described beam delivery system is arranged on the rear end of sleeve pipe, is used for guiding the light beam that sends of light source, and it comprises fibre core, optical fiber coating and light source, and wherein the central shaft of fibre core overlaps with the central shaft of sleeve pipe; Optical fiber coating is coated in the outside surface of fibre core, is used for protecting fibre core;
Described optical fiber contact pins is arranged on the position of inside pipe casing near rear end, and core segment stretches in optical fiber contact pins.
2. integrated optical coherence detection probe as claimed in claim 1, it is characterized in that: have an air layer between described imaging lens and beam delivery system, fibre core can move in this air layer.
3. integrated optical coherence detection probe as claimed in claim 1 or 2, is characterized in that: the optical material consistent with imaging lens refractive index selected by described sleeve pipe, or selects lighttight material; When lighttight material selected by sleeve pipe, an aperture is opened in the side need converged near front end and imaging lens reflected light on sleeve pipe.
4. integrated optical coherence detection probe as claimed in claim 1 or 2, it is characterized in that: the integrated optics of described imaging lens is from crown of roll spherical mirror, and it has imaging lens front end and a columniform imaging lens rear end that a radius-of-curvature is the convex spherical of 0.2 ~ 3mm; Described imaging lens rear end part stretches into sleeve.
CN201510249903.8A 2015-05-15 2015-05-15 Integrated optical coherent detection probe Pending CN104932087A (en)

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CN106691373A (en) * 2016-09-28 2017-05-24 天津恒宇医疗科技有限公司 OCT (optical coherence tomography) probe for small cavity and blood vessel endoscope imaging
CN107692969A (en) * 2017-10-11 2018-02-16 深圳英美达医疗技术有限公司 Type optical coherence tomography probe and its imaging system are peeped in one kind

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691373A (en) * 2016-09-28 2017-05-24 天津恒宇医疗科技有限公司 OCT (optical coherence tomography) probe for small cavity and blood vessel endoscope imaging
CN107692969A (en) * 2017-10-11 2018-02-16 深圳英美达医疗技术有限公司 Type optical coherence tomography probe and its imaging system are peeped in one kind

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