CN104906658B - A kind of continuous injecting systems of large capacity and its control method - Google Patents

A kind of continuous injecting systems of large capacity and its control method Download PDF

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Publication number
CN104906658B
CN104906658B CN201510296776.7A CN201510296776A CN104906658B CN 104906658 B CN104906658 B CN 104906658B CN 201510296776 A CN201510296776 A CN 201510296776A CN 104906658 B CN104906658 B CN 104906658B
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Prior art keywords
flow
syringe pump
electrically
controlled valve
woven hose
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CN104906658A (en
Inventor
宋维业
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Changchun Micro Era Technology Co Ltd
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Changchun Micro Era Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic

Abstract

The invention discloses a kind of continuous injecting systems of large capacity, including fluid reservoir, woven hose, the first syringe pump, the second syringe pump, the first electrically-controlled valve, the second electrically-controlled valve and controller.Woven hose is provided with inlet end and an outlet end, and the port of export of woven hose is connected in the fluid reservoir.First electrically-controlled valve, the first syringe pump, the second electrically-controlled valve and the second syringe pump are consecutively connected on woven hose, pass through the co-ordination of the two syringe pumps, it can realize and continuously be injected with constant target flow, the injection of large capacity can be carried out, and take full advantage of the high-precision advantage of syringe pump.

Description

A kind of continuous injecting systems of large capacity and its control method
Technical field
The present invention relates to injection pump technical field, more particularly to it is a kind of can the injecting systems continuously injected of large capacity and its Control method.
Background technology
Syringe pump is made of stepper motor and its driver, screw and stent etc., has the screw moved back and forth, nut, Therefore also referred to as screw pumps.Nut is connected with the piston of syringe, and liquid is held in syringe, realizes high-precision, steady acrotism Dynamic liquid transmission.
Peristaltic pump is a kind of device that can continuously carry out liquid feed, but its precision is not high, can be produced during feeding intake Raw larger pulsation, so as to influence the process to feed intake.Although syringe pump precision is very high, general syringe pump can only inject fixation The liquid of capacity, some syringe pumps with extract function are extracted, could be noted next time after the completion of injection It penetrates, when extraction, injection will suspend, and influence general injection process.Conventional solution is using the larger note of capacity Pump is penetrated, but the bigger precision of capacity can also reduce accordingly.Therefore being badly in need of offer one kind had both made injection pump capacity smaller to meet essence The device that degree requirement can be injected continuously again.
Invention content
The present invention has designed and developed a kind of continuous injecting systems of large capacity, overcome in the prior art peristaltic pump low precision and The defects of general syringe pump is unable to continuous work, employing the mode of two injection series connections of pumps realizes continuous work and ensures height Precision.
Technical solution provided by the invention is：
A kind of continuous injecting systems of large capacity, including：
Fluid reservoir is used to store liquid to be injected；
Woven hose is provided with inlet end and an outlet end, and the port of export of the woven hose is connected in the fluid reservoir, with The input end of liquid storage pot liquid from the woven hose is transported to the port of export of the woven hose, the woven hose enters Mouth end is inserted into the bottom of the fluid reservoir；
First syringe pump has the function of inwardly to draw and inject outward, first syringe pump and the woven hose Connection, and between the inlet end and an outlet end of the woven hose；
Second syringe pump, identical with first injecting pump structure, second syringe pump is connect with the woven hose, And between first syringe pump and the woven hose port of export；
First electrically-controlled valve is set to the input end on the woven hose and positioned at the woven hose and the described first injection Between pump；
Second electrically-controlled valve is set on the woven hose and is injected between first syringe pump with described second Between pump；
Controller is connect with first syringe pump, the second syringe pump, the first electrically-controlled valve, the second electrically-controlled valve, with control First electrically-controlled valve and the second electrically-controlled valve are turned on and off and control first syringe pump, the second syringe pump to draw Or injection.
Preferably, first syringe pump includes
Pump barrel is arranged to hollow cylinder, and the pump barrel front end is provided with pump mouth, and the pump mouth connects with the woven hose It connects；
Piston core pin is matched with the pump barrel, and the piston core pin realizes the absorption of the syringe pump by pushing and pulling Or injection；
Piston driver is connect with the piston core pin, can drive the front and rear push-and-pull movement of the piston core pin.
Preferably, the piston driver includes：
Motor；
Leading screw is connect with the motor, is rotated under motor driving；
Guide rail, the guide rail are set as 2, respectively at left and right sides of the leading screw, and are arranged in parallel with the leading screw；
Mobile base, is provided with leading screw matching hole and guide rail matching hole, and the leading screw matching hole matches with the leading screw It closes, the guide rail matching hole is matched with the guide rail, and the Mobile base can be moved forward and backward under the driving of the motor；
Wherein, clamping part is additionally provided on the Mobile base, the clamping part can be with the tail end phase of the piston core pin It is fixed.
Preferably, the piston driver further includes linear displacement transducer, the linear displacement transducer and institute It states Mobile base to be connected, to detect the displacement of the Mobile base movement.
Preferably, it is provided between second syringe pump and the woven hose port of export on the woven hose Third electrically-controlled valve.
Preferably, liquid level sensor is provided in the fluid reservoir, to detect the height of the liquid storage pot liquid.
Preferably, flow sensor is provided at the port of export of the woven hose, to detect the outlet of the woven hose Hold the flow of trickle.
A kind of control method of the continuous injecting systems of large capacity, the continuous injecting systems of above-mentioned large capacity, and including following Step：
Step 1: the first electrically-controlled valve is opened, the second electrically-controlled valve is closed, control the first syringe pump liquid draw from fluid reservoir Body medicament is until the first syringe pump is filled；
Step 2: the first electrically-controlled valve is closed, the second electrically-controlled valve opening, the first syringe pump of control is with flow Q1Injection outward Liquid preparation, while the second syringe pump is controlled with flow Q2Draw liquid preparation, and flow Q1Gradually increase, flow Q2Also gradually Increase, and make flow Q1With flow Q2Difference be equal to target flow Qobj；
Step 3: the injection flow Q by the first syringe pump1Flow Q is drawn with the second syringe pump2It continuously decreases, ensures simultaneously Flow Q1With flow Q2Difference be equal to target flow Qobj, until flow Q2It is reduced to 0；
Step 4: make the second syringe pump with flow Q3Outside injecting fluid, and the flow Q3The gradually increase since 0, Make the injection flow Q of the first syringe pump simultaneously1It is gradually reduced, and ensures flow Q3With flow Q1The sum of be equal to target flow Qobj, Until flow Q1It is reduced to 0；
Step 5: the first electrically-controlled valve is opened, the closing of the second electrically-controlled valve, the first syringe pump of control is quickly inhaled from fluid reservoir Liquid preparation is taken, while controls the second syringe pump with constant target flow QobjOutside injecting fluid medicament, until the first syringe pump 130 are filled；
Step 6: the first electrically-controlled valve is closed, the second electrically-controlled valve is opened, and makes the first syringe pump with flow Q1Injection outward Liquid, and the flow Q1The gradually increase since 0, while the flow Q that the second syringe pump 140 is controlled to inject outward3From Qobj Start to be gradually reduced, and ensure flow Q1With flow Q3The sum of be equal to target flow Qobj, until flow Q3Equal to 0；
Step 7: repeating step 2 to step 6, injection process is made constantly to recycle, to realize the port of export with constant target Flow QobjContinuous injection, when the total measurement (volume) of the liquid preparation flowed out from the port of export meets sets requirement, makes the first syringe pump It is stopped with the second syringe pump, completes injection process.
Preferably, in from step 2 to step 6, each step duration is t0；
The flow Q that first syringe pump is injected outward1Meet
The flow Q that second syringe pump is inwardly drawn2Meet
The flow Q that second syringe pump is injected outward3Meet
Wherein, A1For first flow increment, A2For second flow increment, the first flow increment A1Increase with second flow Measure A2It is constant value, t is any time；
First flow increment A1With second flow increment A2Meet following relationship：
Preferably, in step 7, as object time tobjMeet
When, even if the first syringe pump and the second syringe pump are stopped, so as to complete entire injection process；Wherein, VobjFor The totality of the liquid preparation of demand.
The beneficial effects of the invention are as follows：The continuous injecting systems of large capacity provided by the invention inject series connection of pumps using two Technical solution by the co-ordination of the two syringe pumps, can realize and just continuously be injected with constant target flow, can It realizes the injection process of large capacity, and takes full advantage of the high-precision advantage of syringe pump.
Description of the drawings
Fig. 1 is the general structure schematic diagram of the continuous injecting systems of large capacity of the present invention.
Fig. 2 is injecting pump structure schematic diagram of the present invention.
Fig. 3 is pump barrel of the present invention and piston core pin installation diagram.
Fig. 4 is Mobile base structure diagram of the present invention.
Fig. 5 is the control method flow chart of the continuous injecting systems of large capacity of the present invention.
Fig. 6 is the first syringe pump of the present invention and the second syringe pump working flow functional arrangement.
Specific embodiment
The present invention is described in further detail below in conjunction with the accompanying drawings, to enable those skilled in the art with reference to specification text Word can be implemented according to this.
As shown in Figure 1, the present invention provides a kind of continuous injecting systems of large capacity, including fluid reservoir 110, woven hose 120, First syringe pump 130, the second syringe pump 140, the first electrically-controlled valve 150, the second electrically-controlled valve 160 and controller 170.
Fluid reservoir 110 is arranged to the open hollow cylindrical in top, and the fluid reservoir 110 holds liquid medicine to be injected Agent.120 both ends of woven hose are respectively arranged with input end 121 and the port of export 122, and the input end 121 is inserted into fluid reservoir 110 It is interior, the channel of liquid preparation circulation is formed among woven hose 120, can make liquid preparation out of fluid reservoir 110 through woven hose 120 Input end 121 be passed at the port of export 122.
First syringe pump 130 and the second syringe pump 140 are consecutively connected on woven hose 120, the first syringe pump 130 close into Mouth end 121, the second syringe pump 140 is close to the port of export 122.First syringe pump 130 and the second syringe pump 140 have identical knot Structure, they all have the function of inwardly to draw liquid preparation and outside injecting fluid medicament.
First electrically-controlled valve 150 and the second electrically-controlled valve 160 are arranged on woven hose 120, and the first electrically-controlled valve 150 is located at import End 121 and first is between syringe pump 130, and the second electrically-controlled valve 160 is between the first syringe pump 130 and the second syringe pump 140, and the One electrically-controlled valve 150 and the second electrically-controlled valve 160 can be turned on and off, so as to end woven hose 120 or be connected.
Controller 170 respectively with the first syringe pump 130, the second syringe pump 140, the first electrically-controlled valve 150, the second electrically-controlled valve 160 connections are turned on and off and control first note with control 150 and second electrically-controlled valve 160 of the first electrically-controlled valve Penetrate pump 130, the second syringe pump 140 is drawn or is injected, while control the first syringe pump 130, the second syringe pump 140 draw or The flow of injection.
By this arrangement, the first syringe pump 130, the second syringe pump 140 can be made to cooperate, lasting note It penetrates.Specifically after the first syringe pump 130 draws full liquid preparation, the first electrically-controlled valve 150 is closed, opens the second electrically-controlled valve 160, First syringe pump, 130 outside injecting fluid medicament, while the second syringe pump 140 inwardly draws liquid preparation, makes from the first injection A liquid preparation part for 130 outflow of pump is drawn by the second syringe pump 140, and another part is flowed out from the port of export 122, and when first When liquid injection goes out most or all injects away in syringe pump 130, the first electrically-controlled valve 150 is opened, it is automatically controlled to close second Valve 160 makes the first syringe pump 130 draw liquid preparation from fluid reservoir 110, and 140 outside injecting fluid medicament of the second syringe pump, Be achieved it is lasting at the port of export 122 there is liquid preparation to flow through, realize continuous injection process.
In another embodiment, on the woven hose 120 between second syringe pump 140 and the port of export 122 It is provided with third electrically-controlled valve 180.Third electrically-controlled valve 180 is connect with controller 170, is realized and is opened under the control of controller 170 Or it closes.When the continuous injecting systems normal work of the large capacity, third electrically-controlled valve 180 need to be made to be in opening, so as to Liquid preparation is enable to be flowed out from the port of export 122；When the continuous injecting systems of the large capacity are stopped, third need to be made automatically controlled Valve 180 is closed, so that it is guaranteed that liquid preparation will not be flowed out from the port of export 122, is prevented due to failure or human error Increase injection dosage.
As shown in Figure 2 and Figure 3, in another embodiment, first syringe pump 130 includes pump barrel 131, piston core pin 132 And piston driver.Pump barrel 131 is arranged to hollow cylinder, and pump mouth 133 is provided in the front end of pump barrel 131, described Pump mouth 133 is connect with the woven hose 120.Piston core pin 132 is matched with the pump barrel 131, they have collectively constituted injection Syringe.Piston core pin 132 realizes the absorption or injection of syringe pump 130 by push-and-pull.Piston driver and piston core pin 132 Connection, piston driver can drive the front and rear push-and-pull movement of piston core pin 132, it is achieved thereby that the absorption of syringe pump 130 or Injection.
Together refering to Fig. 4, in another embodiment, the piston driver includes motor 134, leading screw 135a, guide rail 136a and Mobile base 137.Wherein motor 134 uses stepper motor or servo motor.Leading screw 135a uses trapezoidal screw or rolling Ballscrew, motor 134 are fixedly and coaxially connected with leading screw 135a, and leading screw 135a can revolve under the driving of motor 134 around rotary shaft Turn.Guide rail 136a is arranged to cylindrical optical axis, and guide rail 136a is provided with 2, respectively at left and right sides of leading screw 135a, and with Leading screw 135a is arranged in parallel.Leading screw matching hole 135b and guide rail matching hole 136b, leading screw matching hole are provided on Mobile base 137 135b is matched with the leading screw 135a, and guide rail matching hole 136b is matched with the guide rail 136a, and Mobile base 137 is enable to exist Tandem moves under the driving of motor 134.Clamping part 138 is provided in the top of Mobile base 137, clamping part 138 is arranged to Two U-type grooves, clamping part 138 can mutually be fixed with the tail end of piston core pin 132, it is achieved thereby that passing through the straight of Mobile base 137 Line moves that piston core pin 132 is driven to be drawn or injected.It is preferred as one kind, straight line position is connected on Mobile base 137 Displacement sensor 139, to measure the displacement of the movement of Mobile base 137.Grating scale may be used in linear displacement transducer 139.It will measure The obtained displacement signal of Mobile base 137 as a feedback signal, to control the rotation of motor, realizes a closed-loop Control, the moving displacement for making Mobile base 137 is more accurate.
In another embodiment, liquid level sensor 111 is provided in the fluid reservoir 110, to detect the fluid reservoir The height of liquid in 110 needs warning reminding operating personnel to mend in time when the height of liquid in fluid reservoir 110 is less than warning value Liquid.
In another embodiment, flow sensor 190 is provided at the port of export 122, is flowed out with detection from the port of export 122 Liquid preparation flow, by measuring obtained flow value, can verify liquid preparation from 122 outflow process of the port of export whether There are pulsation and the accuracy of detection flows.
In another embodiment, arrival end 121 is inserted into the bottom of the fluid reservoir 110, so as to make absorption liquid preparation Process reach better effect.
In another embodiment, pressure sensor and air bubble sensor are additionally provided in pump barrel 131.Pass through pressure sensing Device detects the pressure of interior liquid preparation in pump barrel in real time, prevents pump barrel 131 or woven hose 120 caused by pressure is excessive from being pressed It splits.Bladdery presence is detected whether by being arranged on the air bubble sensor in pump barrel 131, in time will be needed if having bubble Bubble is discharged, in order to avoid influence injection precision.
As shown in figure 5, the present invention also provides a kind of control method of the continuous injecting systems of large capacity, including walking as follows Suddenly：
Step 1 S210：First electrically-controlled valve 150 is opened, the second electrically-controlled valve 160 is closed, and controls the first syringe pump 130 Liquid preparation is drawn from fluid reservoir 110 up to the first syringe pump 130 is filled.
Step 2 S220：After the first syringe pump 130 is filled, the first electrically-controlled valve 150 is closed, the second electrically-controlled valve 160 is beaten It opens, and controls the first syringe pump 130 with flow Q1Outside injecting fluid medicament, while the second syringe pump 140 is controlled with flow Q2It inhales Take liquid preparation, and flow Q1Gradually increase, flow Q2Also gradually increase, i.e., the liquid preparation one flowed out from the first syringe pump 130 Part is drawn by the second syringe pump 140, and another part port of export 122 flows out, and realizes as 140 filling liquid of the second syringe pump.First The flow Q that syringe pump 130 is injected1Gradually increase, the absorption flow Q of the second syringe pump 1402Also gradually increase, but need to ensure flow Q1With flow Q2Difference be equal to target flow Qobj, i.e., the port of export 122 is with constant target flow value QobjCarry out feed flow.
Step 3 S230：After the second syringe pump 140 draws the liquid preparation of certain capacity, by the first syringe pump 130 Inject flow Q1Flow Q is drawn with the second syringe pump 1402It continuously decreases, while ensures flow Q1With flow Q2Difference be equal to target Flow Qobj, until flow Q20 is reduced to, i.e. the second syringe pump 140 no longer draws liquid preparation.
Step 4 S240：Second syringe pump 140 switchs to injection state, i.e., the second syringe pump 140 is with flow Q3Injection outward Liquid, and the flow Q3The gradually increase, while make the injection flow Q of the first syringe pump since 01It is gradually reduced, and ensures Flow Q3With flow Q1The sum of be equal to target flow Qobj, until flow Q10 is reduced to, i.e. the first syringe pump 130 is no longer noted outward Liquid preparation is penetrated, the flow Q that the second syringe pump 140 is injected outward at this time3Equal to target flow Qobj。
Step 5 S250：First electrically-controlled valve 150 is opened, the second electrically-controlled valve 160 is closed, the first syringe pump 130 of control is fast Speed draws liquid preparation up to the first syringe pump 130 is filled, while controls the second syringe pump 140 with constant from fluid reservoir 110 Target flow QobjOutside injecting fluid medicament, until the first syringe pump 130 is filled.
Step 6 S260：After the first syringe pump 130 is filled, the first electrically-controlled valve 150 is closed, the second electrically-controlled valve 160 is beaten It opens, and makes the first syringe pump 130 with flow Q1Outside injecting fluid, and the flow Q1Gradually increase, same time control since 0 Make the flow Q that the second syringe pump 140 is injected outward3From QobjStart to be gradually reduced, and ensure flow Q1With flow Q3The sum of be equal to Target flow Qobj, until flow Q3Equal to 0, i.e., the second syringe pump 140 completes outside injection process.
Step 7：Step 2 S220 to step 6 S260 is repeated, injection process is made constantly to recycle, to realize the port of export 122 With constant target flow QobjContinuous injection, until the total measurement (volume) of the liquid preparation flowed out from the port of export 122 meets sets requirement When, the first syringe pump 130 and the second syringe pump 140 is made to be stopped, completes injection process.It simultaneously need to be by third electrically-controlled valve 180 It closes, the liquid preparation caused by failure and other reasons is avoided accidentally to be flowed at the port of export 122.
In another embodiment, in step 7, can be judged according to the time from 122 trickle medicament of the port of export Total volume has reached setting value, was 0 moment at the time of step 2 S220 is enabled to start for the first time, i.e., starts in the 0 moment port of export 122 With constant target flow QobjOutside injecting fluid medicament, sets the total volume of liquid preparation as Vobj, then as object time tobj Meet
When, the first syringe pump 130 and the second syringe pump 140 is made to be stopped immediately, so as to complete entire injection process.
In another embodiment, from step 2 S220 to step 6 S260, each step duration is t0, such as Shown in Fig. 6, solid line lines represent the working flow of the first syringe pump 130, and dashed lines represent the workflow of the second syringe pump 140 Amount.
Step 2 S220 is since 0 moment, and in step 2 S220, flow that the first syringe pump 130 is injected outward Q1Meet
Q1=Qobj+A1T, t ∈ [0, t0]
Wherein, A1For first flow increment, it is expressed as the value added of flow in the unit interval, the first flow increment A1 For constant value；T is any time.
The flow Q that second syringe pump 140 is drawn2Meet
Q2=A1T, t ∈ [0, t0]。
In Fig. 6, flow Q2In the negative sense of the longitudinal axis, flow Q is represented2For the flow inwardly drawn.From the above equation, we can see that due to One flow increment A1The flow Q injected outward for constant, the first syringe pump 1301The flow inwardly drawn with the second syringe pump 140 Q2It is smoothly to increase, the pulsation during liquid flowing can be reduced in this way, is conducive to the smooth flow of liquid.And the The flow Q that one syringe pump 130 is injected outward1The flow Q inwardly drawn with the second syringe pump 1402Difference be equal to target flow Qobj。
Step 3 S230 is from t=t0Moment, and in step 3 S230, what the first syringe pump 130 was injected outward Flow Q1Meet
Q1=Qobj+2A1t0-A1T, t ∈ [t0,2t0]
The flow Q that second syringe pump 140 is drawn2Meet
Q2=2A1t0-A1T, t ∈ [t0,2t0]。
From the above equation, we can see that the flow Q that the first syringe pump 130 is injected outward1The flow inwardly drawn with the second syringe pump 140 Q2It is smoothly to reduce, the pulsation during liquid flowing can be reduced in this way, is conducive to the smooth flow of liquid.Simultaneously again It ensure that the flow Q that the first syringe pump 130 is injected outward1The flow Q inwardly drawn with the second syringe pump 1402Difference be equal to target Flow Qobj。
Step 4 S240 is from t=2t0Moment, and in step 4 S240, what the first syringe pump 130 was injected outward Flow Q1Meet
Q1=Qobj-A2(t-2t0), t ∈ [2t0,3t0],
Wherein A2For second flow increment, it is expressed as the value added of flow in the unit interval, the second flow increment A2For Constant value；Due in t=3t0At the time of, flow Q that the first syringe pump 130 is injected outward1It is 0, thus it is available
The flow Q that second syringe pump 140 is injected outward3Meet
Q3=A2(t-2t0), t ∈ [2t0,3t0]。
From the above equation, we can see that in step 4 S240, the first syringe pump 130 and the second syringe pump 140 outside parenteral solution simultaneously Body medicament, due to second flow increment A2For constant, so the flow Q that the first syringe pump 130 is injected outward1It is smoothly to reduce, The flow Q that second syringe pump 140 is injected outward3It is smoothly to increase, the pulsation during liquid flowing can be reduced in this way, had Conducive to the smooth flow of liquid.In turn ensure the flow Q that the first syringe pump 130 is injected outward simultaneously1With the second syringe pump 140 to The flow Q of outer injection3The sum of be equal to target flow Qobj。
Step 5 S250 is from t=3t0Moment, in step 5 S250 from t=3t0To t=4t0Period in, second Syringe pump 140 is always with flow Q3=QobjOutside injecting fluid medicament, and the first syringe pump 130 within this end time from liquid storage Liquid preparation is drawn in tank 110.
Step 6 S260 is from t=4t0Moment, and in step 6 S260, what the first syringe pump 130 was injected outward Flow Q1Meet
Q1=A2(t-4t0), t ∈ [4t0,5t0],
The flow Q that second syringe pump 140 is injected outward3Meet
Q3=Qobj-A2(t-4t0), t ∈ [4t0,5t0]。
From the above equation, we can see that in step 6 S260, the first syringe pump 130 has been filled with liquid preparation, the first syringe pump 130 from t=4t0Moment starts flow Q1The gradually increase since 0, due to second flow increment A2For constant, so the first injection The flow Q that pump 130 is injected outward1It is smoothly to increase, the flow Q that the second syringe pump 140 is injected outward3It is smoothly to reduce, this Sample can reduce the pulsation during liquid flowing, be conducive to the smooth flow of liquid.In turn ensure the first syringe pump 130 simultaneously The flow Q injected outward1The flow Q injected outward with the second syringe pump 1403The sum of be equal to target flow Qobj。
In another embodiment, the first flow increment A1Meet following relationship：
By making first flow increment A1Meet above-mentioned relation formula, can be calculated in step 2 S220 and step 3 In S230, the total measurement (volume) V for the liquid preparation that the second syringe pump 140 is inwardly drawn1For
In step 4 S240 to step 6 S260, the total measurement (volume) V for the liquid preparation that the second syringe pump 140 is injected outward2 For
By the V being calculated1And V2It is found that the second syringe pump 140 is inwardly drawn in step 2 S220 and step 3 S230 Liquid preparation total measurement (volume) V1, with the liquid that the second syringe pump 140 is injected outward in step 4 S240 to step 6 S260 The total measurement (volume) V of medicament2It is equal.
In the above-mentioned technical solutions, in step 2 S220 and step 3 S230, the liquid medicine of the second syringe pump 140 absorption The total measurement (volume) V of agent1, equal to the total measurement (volume) of the liquid preparation that the second syringe pump 140 is injected in step 2 S240- step 6 S260 V2.If the total volume of liquid preparation that the second syringe pump 140 is drawn in step 2 S220 and step 3 S230, less than in step The total volume for the liquid preparation that the second syringe pump 140 is injected, then make in step 2 S240- steps in two S240- step 6 S260 The second syringe pump 140 has not been completed injection process in six S260, and the liquid preparation in the second syringe pump 140 has been used up, it is impossible to Continue to inject, entire injection circulation can be prevented from continuing.If the second syringe pump 140 is in step 2 S220 and step 3 S230 The total volume of the liquid preparation of middle absorption, more than the liquid that the second syringe pump 140 is injected in step 2 S240- step 6 S260 The total volume of medicament then after the absorption injection circulation of second syringe pump 140, can remain in the second syringe pump 140 Some liquid preparations, after multiple cycles, residual liquid medicament will continue to accumulate in the second syringe pump 140, until being more than After the total measurement (volume) of second syringe pump 140, above-mentioned technical proposal can not continue.
As pump barrel a kind of preferred, that selection volume is 25ml, setting target flow Qobj=2ml/s, from step 2 In S220 to step 6 S260, each step duration t0=2s, first flow increment A1=2ml/s2, second flow increasing Measure A2=1ml/s2。
Although the embodiments of the present invention have been disclosed as above, but its be not restricted in specification and embodiment it is listed With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily Realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, it is of the invention and unlimited In specific details and legend shown and described herein.

Claims (8)

1. a kind of continuous injecting systems of large capacity, which is characterized in that including：
Fluid reservoir is used to store liquid to be injected；
Woven hose is provided with inlet end and an outlet end, and the port of export of the woven hose is connected in the fluid reservoir, by institute The input end for stating liquid storage pot liquid from the woven hose is transported to the port of export of the woven hose, the arrival end of the woven hose It is inserted into the bottom of the fluid reservoir；
First syringe pump has the function of inwardly to draw and inject outward, and first syringe pump is connect with the woven hose, And between the inlet end and an outlet end of the woven hose；
Second syringe pump has the function of inwardly to draw and inject outward, and second syringe pump is connect with the woven hose, And between first syringe pump and the woven hose port of export；
First electrically-controlled valve, be set on the woven hose and the input end positioned at the woven hose and first syringe pump it Between；
Second electrically-controlled valve, be set on the woven hose and between first syringe pump with second syringe pump it Between；
Controller is connect with first syringe pump, the second syringe pump, the first electrically-controlled valve, the second electrically-controlled valve, with described in control Be turned on and off and control first syringe pump, the second syringe pump of first electrically-controlled valve and the second electrically-controlled valve are drawn or note It penetrates；
First syringe pump includes:
Pump barrel is arranged to hollow cylinder, and the pump barrel front end is provided with pump mouth, and the pump mouth is connect with the woven hose；
Piston core pin is matched with the pump barrel, and the piston core pin realizes absorption or the note of the syringe pump by pushing and pulling It penetrates；
Piston driver is connect with the piston core pin, can drive the front and rear push-and-pull movement of the piston core pin；
The piston driver includes:
Motor；
Leading screw is connect with the motor, is rotated under motor driving；
Guide rail, the guide rail are set as 2, respectively at left and right sides of the leading screw, and are arranged in parallel with the leading screw；
Mobile base is provided with leading screw matching hole and guide rail matching hole, and the leading screw matching hole is matched with the leading screw, institute It states guide rail matching hole to match with the guide rail, the Mobile base can be moved forward and backward under the driving of the motor；
Wherein, clamping part is additionally provided on the Mobile base, is two U-type groove structures, the clamping part can be with the work The tail end of plug core bar is mutually fixed.
2. according to the continuous injecting systems of large capacity described in claim 1, which is characterized in that the piston driver further includes directly Linear movement pick-up, the linear displacement transducer are connected with the Mobile base, to detect the displacement of the Mobile base movement.
3. the continuous injecting systems of large capacity according to claim 1, which is characterized in that be located on the woven hose described Third electrically-controlled valve is provided between second syringe pump and the woven hose port of export.
4. the continuous injecting systems of large capacity according to claim 1, which is characterized in that be provided with liquid level in the fluid reservoir Sensor, to detect the height of the liquid storage pot liquid.
5. the continuous injecting systems of large capacity according to claim 1, which is characterized in that set at the port of export of the woven hose Flow sensor is equipped with, to detect the flow of the port of export trickle of the woven hose.
6. a kind of control method of the continuous injecting systems of large capacity, which is characterized in that using described in any one of claim 1-5 The continuous injecting systems of large capacity, and include the following steps：
Step 1: the first electrically-controlled valve is opened, the closing of the second electrically-controlled valve, the first syringe pump of control draws liquid medicine from fluid reservoir Agent is until the first syringe pump is filled；
Step 2: the first electrically-controlled valve is closed, the second electrically-controlled valve opening, the first syringe pump of control is with flow Q1Outside injecting fluid Medicament, while the second syringe pump is controlled with flow Q2Draw liquid preparation, and flow Q1Gradually increase, flow Q2Also gradually increase, And make flow Q1With flow Q2Difference be equal to target flow Qobj；
Step 3: the injection flow Q by the first syringe pump1Flow Q is drawn with the second syringe pump2It continuously decreases, while ensures flow Q1With flow Q2Difference be equal to target flow Qobj, until flow Q2It is reduced to 0；
Step 4: make the second syringe pump with flow Q3Outside injecting fluid, and the flow Q3The gradually increase since 0, simultaneously Make the injection flow Q of the first syringe pump1It is gradually reduced, and ensures flow Q3With flow Q1The sum of be equal to target flow Qobj, until Flow Q1It is reduced to 0；
Step 5: the first electrically-controlled valve is opened, the closing of the second electrically-controlled valve, the first syringe pump quickly liquid draw from fluid reservoir is controlled Body medicament, while the second syringe pump is controlled with constant target flow QobjOutside injecting fluid medicament, until the first injection pumping It is full；
Step 6: the first electrically-controlled valve is closed, the second electrically-controlled valve is opened, and makes the first syringe pump with flow Q1Outside injecting fluid, And the flow Q1The gradually increase since 0, while the flow Q that the second syringe pump is controlled to inject outward3From QobjStart gradual Reduce, and ensure flow Q1With flow Q3The sum of be equal to target flow Qobj, until flow Q3Equal to 0；
Step 7: repeating step 2 to step 6, injection process is made constantly to recycle, to realize the port of export with constant target flow QobjContinuous injection when the total measurement (volume) of the liquid preparation flowed out from the port of export meets sets requirement, makes the first syringe pump and the Two syringe pumps are stopped, and complete injection process.
7. the control method of the continuous injecting systems of large capacity according to claim 6, which is characterized in that
In from step 2 to step 6, each step duration is t0；
The flow Q that first syringe pump is injected outward1Meet
The flow Q that second syringe pump is inwardly drawn2Meet
The flow Q that second syringe pump is injected outward3Meet
Wherein, A1For first flow increment, A2For second flow increment, the first flow increment A1With second flow increment A2 For constant value, t is any time；
First flow increment A1With second flow increment A2Meet following relationship：
8. the control method of the continuous injecting systems of large capacity according to claim 7, which is characterized in that in step 7, As object time tobjMeet
When, even if the first syringe pump and the second syringe pump are stopped, so as to complete entire injection process；Wherein, VobjFor demand Liquid preparation totality.
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