CN104873673A - Plaster for treating osteoarthritis and preparation method - Google Patents

Abstract

The invention discloses plaster for treating osteoarthritis and a preparation method. The plaster is composed of the following bulk drugs of rhizoma curculiginis, trigonella foenum-graecum, black chicken bones, deer bones, oxhide gelatin, cinnamomum pauciflorum skin, cinnamomum camphora roots, aristolochia fordiana, prettyleaf silkvine stems, resina liquidamberis, martianus dermestoides, cosymbotus platyurus and Chinese gall. The paste is made of the oxhide gelatin serving as excipient. The plaster for treating osteoarthritis overcomes the defects that plaster components for treating osteoarthritis are mostly used for dredging and less use a reinforcing method, dredging and reinforcing are both implemented, and the treatment mechanism is more reasonable. Clinical application proves that the curative effect for treating osteoarthritis is positive, the oxhide gelatin serves as the excipient, the toxic and side effects of shot medicine are eliminated, and medicine use is safer.

Description

A kind of plaster and preparation method for the treatment of osteoarthritis

Technical field

The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of plaster and preparation method for the treatment of osteoarthritis.

Background technology

Osteoarthritis is one of common rheumatism, and be more common in old people, according to Epidemiological study, in the crowd of 55 ~ 64 years old, sickness rate reaches 40%.China enters aging society, and the sickness rate of osteoarthritis presents ascendant trend.Though anti-inflammation and analgesic drugs energy relief of symptoms, the development of the uncontrollable state of an illness, and side effect is more.Plaster use safety, having no side effect, meet compatriots' medication custom, is the common formulations for the treatment of osteoarthritis.Osteoarthritis belongs to Chinese medicine " rheumatism involving the bone " category, and pathogenesis is vital QI being weakened and pathogen being violent.According to the Therapeutic Principle of " actually clear profit, void is tonification then ", the treatment for this disease should adopt " logical method " and " reinforcement ".But plaster formula is main mainly with " leading to " in clinical practice, few with " reinforcement ", therapy mechanism is not comprehensive, affects the treatment.The present inventor, by long-term clinical practice, develops a kind of Chinese medicine composition for the treatment of osteoarthritis, satisfactory effect.

Summary of the invention

The object of the invention is to overcome the deficiency without the rational plaster for the treatment of osteoarthritis compatibility in prior art, namely a kind of plaster and preparation method for the treatment of osteoarthritis are provided.

In order to realize foregoing invention object, the invention provides following technical scheme: a kind of plaster for the treatment of osteoarthritis, be made up of the crude drug of following mass ratio: Rhizoma Curculiginis 15 ~ 25 parts, Semen Trigonellae 15 ~ 25 parts, Os Gallus Domesticus 30 ~ 50 parts, Os Cervi 30 ~ 50 parts, gelatinum oxhide 80 ~ 120 parts, 10 ~ 20 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 10 ~ 20 parts, Radix Aristolochiae Tagalae 10 ~ 20 parts, Caulis Periplocae Calophyllae 10 ~ 20 parts, Resina Liquidambaris 9 ~ 15 parts, Martianus dermestoides Chevr. 6 ~ 10 parts, lizard tiger 6 ~ 10 parts, Galla Chinensis 9 ~ 15 parts.

Preferably, the plaster of described treatment osteoarthritis, is made up of the crude drug of following mass ratio: Rhizoma Curculiginis 20 parts, Semen Trigonellae 20 parts, Os Gallus Domesticus 40 parts, Os Cervi 40 parts, gelatinum oxhide 100 parts, 15 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 15 parts, Radix Aristolochiae Tagalae 15 parts, Caulis Periplocae Calophyllae 15 parts, Resina Liquidambaris 12 parts, Martianus dermestoides Chevr. 8 parts, lizard tiger 8 parts, Galla Chinensis 12 parts.

The preparation method of the plaster for the treatment of osteoarthritis:

Get each crude drug in proportion, Rhizoma Curculiginis, Semen Trigonellae, Os Gallus Domesticus, Os Cervi, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae, Radix Aristolochiae Tagalae, Caulis Periplocae Calophyllae, Resina Liquidambaris, Martianus dermestoides Chevr., lizard tiger, Galla Chinensis are pulverized, it is for subsequent use that mistake 100 mesh sieves make medicated powder; Get and medicated powder equal quality water soaking gelatinum oxhide, be heated to melt completely, add medicated powder and stir, then stick.

When plaster provided by the invention uses by plaster to sore place, within every three days, change once.

The pharmacological action of raw material of Chinese medicine medicine of the present invention is as follows:

Rhizoma Curculiginis: pungent, hot, poisonous, returns kidney, Liver Channel.Warming the kidney to invigorate YANG, dispelling cold and dehumidification.Cure mainly insufficiency of kidney-YANG, the sexual impotence cold sperm of decline of the fire from the gate of life, frequent micturition; Chills and pain of the waist and kness, muscles and bones flaccidity is soft unable.

Semen Trigonellae: bitter, warm, returns kidney channel.Warming the kidney to activate YANG, dispersing cold for relieving pain.Cure mainly colic of cold type stomachache, abdomen side of body distending pain; Foot knee joint cold type of pain, the disturbance of lower legs due to pathogenic cold and dampness; Sexual impotence lingering diarrhea, cold sperm capsule wets.

Gallus Domesticus: sweet, flat, returns liver, kidney, lung meridian.Invigorating the liver and kidney, replenishing QI and blood, reducing the asthenic fever.Curing mainly asthenia wins thin, and hectic fever due to YIN-deficiency consumptive disease heat, quenches one's thirst, seminal emission, spermatorrhea, chronic diarrhea, chronic dysentery, metrorrhagia, leukorrhagia.

Os Cervi: sweet, warm, returns kidney channel.Tonify deficiency is won, bone and muscle strengthening, promoting tissue regeneration and ulcer healing.Cure mainly asthenia weak bone, rheumatic ostalgia, scrofula, sore.

Gelatinum oxhide: sweet, flat, returns lung, large intestine channel.Nourshing Yin and drynsessmoistening prescription, nourishing blood and hemoslasis, promoting blood circulation and detumescence, removing toxic substances.Cure mainly asthenia consumptive lung disease, cough spitting of blood, tell nosebleed, metrorrhagia, dysentery is had blood in stool, traumatic injury, skin sore, burn and scald.

Fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi): pungent, warm, nontoxic.Warming spleen and stomach for dispelling cold, regulates the flow of vital energy, and promotes blood circulation.Cure mainly cold syndrome of the stomach pain, fullness in the chest is suffered from abdominal pain, and vomiting is had loose bowels, hernia pain, traumatic injury, rheumatic arthralgia, dysentery hemorrhoidal hamorrhage.

Radix Cinnamomi Camphorae: pungent, warm, returns liver, spleen channel.Warming middle-JIAO to relieve pain, and in, damp eliminating.Cure mainly gastralgia, cholera is vomited and diarrhoea, rheumatic arthralgia, skin pruritus etc.

Radix Aristolochiae Tagalae: bitter, pungent, warm, slightly poisonous.Wind-expelling pain-stopping, subduing swelling and detoxicating.Cure mainly heart peratodynia, rheumatic ostalgia, traumatic injury, infantile convulsion, venom.

Caulis Periplocae Calophyllae: pungent, micro-hardship, temperature, mild toxicity.Expelling wind and removing dampness, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, numb limbs and tense tendons, lumbago, traumatic injury.

Resina Liquidambaris: pungent, micro-hardship, flat, returns lung, spleen channel.Promoting blood circulation and stopping pain, hemostasis, removing toxic substances, granulation promoting.Cure mainly rheumatic arthralgia, traumatic injury, heat in blood tells nosebleed, and scrofula, ulcer sore pain, ecthyma does not heal.

Martianus dermestoides Chevr.: warming middle-JIAO is regulated the flow of vital energy, promoting blood circulation and stopping pain.Cure mainly heart peratodynia, abdominal distention is vomited and diarrhoea, traumatic injury, hemiplegia, limbs flaccidity syndrome and arthralgia syndrome, strain cough, menoxenia, leucorrhea with red and white discharge.

Lizard tiger: cold, salty, slightly poisonous, GUIXIN, Liver Channel.Suppressing liver-wind to relieve spasm, promoting blood circulation and detumescence, detoxicating and resolving stagnation of pathogens.Cure mainly infantile convulsion, tetanus, severe and migratory arthralgia pain, paralysis due to windstroke, brothers' erectile problem, infantile malnutrition, furuncle swelling toxin, scrofula goiter, scorpin sting.

Galla Chinensis: sour, puckery, cold, returns lung, large intestine, kidney channel.Astringe the lung pathogenic fire reducing, cough-relieving hidroschesis, relieving diarrhea with astringents, controlling nocturnal emission with astringent drugs is only lost, astringing to arrest bleeding, removing dampness sore.External has local anesthesia effect.

The present invention adopts Rhizoma Curculiginis, Semen Trigonellae warming the kidney to invigorate YANG, dispelling cold and dehumidification; Os Gallus Domesticus, Os Cervi are with bone Psoralen; Gelatinum oxhide promoting blood circulation and detumescence, and as excipient; Fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae warming spleen and stomach for dispelling cold, regulate the flow of vital energy and promote blood circulation; Radix Aristolochiae Tagalae, Caulis Periplocae Calophyllae expelling wind and removing dampness; Resina Liquidambaris promoting blood circulation and stopping pain; Martianus dermestoides Chevr., lizard tiger search the heresy of picking into network; Five times of removing dampness sores, external has local anesthesia effect.All medicines share, through-supplementation, and cure mechanism is more reasonable, therefore receives good effect.

compared with prior art, beneficial effect of the present invention

The plaster for the treatment of osteoarthritis provided by the invention, the plaster formula overcoming treatment osteoarthritis is main mainly with " leading to ", and few abuses with " reinforcement ", through-supplementation, cure mechanism is more reasonable.Clinical confirmation treatment osteoarthritis curative effect certainly, and is excipient with gelatinum oxhide, and eliminate the toxic and side effects of red class medicine, medication is safer.

treat a plaster for osteoarthritis, clinical efficacy is summed up

1 physical data

Man 50 example in 83 examples, female 33 example; Year mean age (54.1 ± 8.7); The course of disease 4.1 ± 1.7) year; Wherein lumbar vertebra osteoarthritis 21 example, Hip osteoarthritis 10 example, knee joint osseous arthritis 45 example, ankle joint osteoarthritis 7 example.

2 Therapeutic Method

The plaster made by the crude drug of Rhizoma Curculiginis 20 parts, Semen Trigonellae 20 parts, Os Gallus Domesticus 40 parts, Os Cervi 40 parts, gelatinum oxhide 100 parts, 15 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 15 parts, Radix Aristolochiae Tagalae 15 parts, Caulis Periplocae Calophyllae 15 parts, Resina Liquidambaris 12 parts, Martianus dermestoides Chevr. 8 parts, lizard tiger 8 parts, Galla Chinensis 12 parts of mass ratios, to sore place, is changed once for every three days.

3 therapeutic outcomes

3.1 criterions of therapeutical effect: formulate with reference to the criterion of therapeutical effect in " Chinese medical disease Standardization of diagnosis and curative effect ".Cure: transference cure, joint function recovery is normal; Effective: arthralgia obviously alleviates, swelling disappears substantially, and function of joint is obviously improved; Effective: pain, swelling, function of joint take a turn for the better; Invalid: after treatment, symptom, sign and function of joint are unchanged.

3.2 results: through treatment in 2 ~ 4 weeks, cure 30 examples, effective 41 examples, effective 9 examples, invalid 3 examples, total effective rate 96.4%.

4 model cases

Zhang, man, 56 years old, double knee joint pain 3 years, increased the weight of 1 month, and X-ray film shows double knee joint degeneration, was diagnosed as two knee osteoarthritis.Use plaster external application provided by the invention, 4 doses and heal.Follow up a case by regular visits to and do not recur for 1 year.

Detailed description of the invention

Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.

Embodiment 1

Treat a plaster for osteoarthritis, be made up of the crude drug of following quality:

Rhizoma Curculiginis 25 grams, Semen Trigonellae 25 grams, Os Gallus Domesticus 50 grams, Os Cervi 50 grams, gelatinum oxhide 120 grams, 20 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 20 grams, Radix Aristolochiae Tagalae 20 grams, Caulis Periplocae Calophyllae 20 grams, Resina Liquidambaris 15 grams, Martianus dermestoides Chevr. 10 grams, lizard tiger 10 grams, Galla Chinensis 15 grams.

Embodiment 2

Treat a plaster for osteoarthritis, be made up of the crude drug of following quality:

Rhizoma Curculiginis 20 grams, Semen Trigonellae 20 grams, Os Gallus Domesticus 40 grams, Os Cervi 40 grams, gelatinum oxhide 100 grams, 15 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 15 grams, Radix Aristolochiae Tagalae 15 grams, Caulis Periplocae Calophyllae 15 grams, Resina Liquidambaris 12 grams, Martianus dermestoides Chevr. 8 grams, lizard tiger 8 grams, Galla Chinensis 12 grams.

Embodiment 3

Treat a plaster for osteoarthritis, be made up of the crude drug of following quality:

Rhizoma Curculiginis 15 grams, Semen Trigonellae 15 grams, Os Gallus Domesticus 30 grams, Os Cervi 30 grams, gelatinum oxhide 80 grams, 10 grams, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 10 grams, Radix Aristolochiae Tagalae 10 grams, Caulis Periplocae Calophyllae 10 grams, Resina Liquidambaris 9 grams, Martianus dermestoides Chevr. 6 grams, lizard tiger 6 grams, Galla Chinensis 9 grams.

The preparation method of the plaster of the treatment osteoarthritis of embodiment 1 ~ 3 is as follows:

Get each crude drug in proportion, Rhizoma Curculiginis, Semen Trigonellae, Os Gallus Domesticus, Os Cervi, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae, Radix Aristolochiae Tagalae, Caulis Periplocae Calophyllae, Resina Liquidambaris, Martianus dermestoides Chevr., lizard tiger, Galla Chinensis are pulverized, it is for subsequent use that mistake 100 mesh sieves make medicated powder; Get and medicated powder equal quality water soaking gelatinum oxhide, be heated to melt completely, add medicated powder and stir, then stick.

Claims (3)

1. treat a plaster for osteoarthritis, it is characterized in that being made up of the crude drug of following mass ratio:

Rhizoma Curculiginis 15 ~ 25 parts, Semen Trigonellae 15 ~ 25 parts, Os Gallus Domesticus 30 ~ 50 parts, Os Cervi 30 ~ 50 parts, gelatinum oxhide 80 ~ 120 parts, 10 ~ 20 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 10 ~ 20 parts, Radix Aristolochiae Tagalae 10 ~ 20 parts, Caulis Periplocae Calophyllae 10 ~ 20 parts, Resina Liquidambaris 9 ~ 15 parts, Martianus dermestoides Chevr. 6 ~ 10 parts, lizard tiger 6 ~ 10 parts, Galla Chinensis 9 ~ 15 parts.

2. the plaster for the treatment of osteoarthritis as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:

Rhizoma Curculiginis 20 parts, Semen Trigonellae 20 parts, Os Gallus Domesticus 40 parts, Os Cervi 40 parts, gelatinum oxhide 100 parts, 15 parts, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae 15 parts, Radix Aristolochiae Tagalae 15 parts, Caulis Periplocae Calophyllae 15 parts, Resina Liquidambaris 12 parts, Martianus dermestoides Chevr. 8 parts, lizard tiger 8 parts, Galla Chinensis 12 parts.

3. the preparation method of the plaster of the treatment osteoarthritis as described in claim 1 ~ 2, is characterized in that:

Get each crude drug in proportion, Rhizoma Curculiginis, Semen Trigonellae, Os Gallus Domesticus, Os Cervi, fragrant Cortex cinnamomi japonici (Ramulus Cinnamomi), Radix Cinnamomi Camphorae, Radix Aristolochiae Tagalae, Caulis Periplocae Calophyllae, Resina Liquidambaris, Martianus dermestoides Chevr., lizard tiger, Galla Chinensis are pulverized, it is for subsequent use that mistake 100 mesh sieves make medicated powder; Get and medicated powder equal quality water soaking gelatinum oxhide, be heated to melt completely, add medicated powder and stir, then stick.