CN104857381A - Traditional Chinese medicine preparation for treating obsessive-compulsive disorder - Google Patents

Abstract

The invention relates to a traditional Chinese medicine preparation for treating obsessive-compulsive disorder. The traditional Chinese medicine preparation is good in treatment effect and small in side effect. The traditional Chinese medicine preparation comprises, by weight, 30-80 parts of lily, 60-90 parts of dogwood, 80-120 parts of rhizoma curculiginis, 10-50 parts of radix rehmanniae, 10-50 parts of ossa draconis, 10-50 parts of oyster, 10-40 parts of polygala tenuifolia, 10-35 parts of radix ophiopogonis, 5-30 parts of schisandra chinensis, 10-50 parts of poria cocos, 10-30 parts of pericarpium citri reticulatae, 60-85 parts of yam rhizome, 60-90 parts of sesamum indicum, 60-90 parts of cynomorium songaricum, 5-30 parts of liquorice, 10-35 parts of caulis bambusae in taeniam, 100-200 parts of the root of red-rooted salvia and 5-20 parts of bamboo juice; and raw materials are mixed into powder.

Description

Treat compulsive Chinese medicine preparation

(1), technical field

What the present invention relates to is a kind of traditional Chinese medicine product, and one is used for the treatment of compulsive Chinese medicine preparation specifically.

(2), background technology

Obsession is a kind of mental maladjustment of cause of disease more complicated, and compulsive clinical manifestation has:

One, obsessive idea

1. force suspection: the correctness of patient to oneself words and deeds throws doubt upon repeatedly, produce compulsive checking behavior afterwards.As suspected whether shut door and window after going out, writing letter and whether misdirect, check for this reason and repeatedly.

2. obsessive rumination: patient thinks repeatedly to some things in daily life or natural phenomena, trace to its source, know perfectly well meaningless, but it is uncontrollable, its thinking is often tangled in the problem that some lack practical significance and can not break away from, this symptom just can be seen in teenager, as thought " why not being chair desk on desk ", " why one-plus-one equals two is but not equal to three ".

3. force association: occur in patient's brain hearing or see a certain idea or certain a word, just recall another idea or words and phrases in spite of oneself.

4. force memory: patient, to the event lived through, repeatedly occurs in spite of oneself in consciousness, though know without this necessary, cannot automatic control.Sometimes force and recall and force suspection to occur simultaneously, patient suspects that when forcing memory from the beginning oneself recall wrong having to again remembers, increases the weight of that it is uneasy and painful; Sometimes patients is stupefied, is actually and is thinking, if interrupted or think " think not to " time, from the beginning must remember again, show agitation because of frightening bothering, hide the retractility performances such as people.

5. force numeration: patient carries out mandatory numeration to the article of definite shape, can not automatic control without this necessity though know.

6. phobia: refer to that patient worries some things or feels sick, it is not right to know perfectly well, unablely extricates oneself.As worried can do by myself harm people, can make a slip of the tongue or make reasonless behavior or worrying that oneself is subject to germ contamination etc.

7. obsessive intentions: patient experiences repeatedly, feels like doing the strong interior cardiac impulse of certain action of running counter to oneself wish or behavior.Although patient knows that this is absurd ideas perfectly well, oneself also can not so do, and cannot break away from this interior cardiac impulse.Walking by the river as having child in arms, occurring the purpose etc. child thrown in river.

8. force opposites viewpoint: the opposed idea with reality often appears in patient's brain back warp, this is often the content of the bad usual moral code of violation, for this reason patient nervous, fear uneasiness but wilfully can not get rid of sometimes even have the impulsion of escaping one's lips, as scolding coarse language etc.

9. force presentation: the content repeatedly presenting iconicity in finger brain, as the image such as genitals, pornographic.

10. obsessive intentions: have another name called and force impulsion is that a kind of strong inherence is ordered about, and is idea is committed to enforcement by a kind of meeting impulsion sense by action.This kind of impulsion is usually injury also property, and as uxoricide goes out son, smash up article, jump the automobile speeded along, or produce appropriate to the occasion impulsion of extremely getting along well, and as at trousers taking off oneself and so in public, this is often with strong fear and uneasiness.

Two, compulsion

Compulsion often for alleviating the anxiety that obsessive idea causes, some compliance behaviors that patient takes in spite of oneself.As:

1. compulsive checking: force the anxiety caused by suspection and the behavior taked for alleviating.

2. force inquiry: patients with OCD often distrusts oneself, exhaust worry anxiety of bringing to dispel one's misgivings or studying carefully think of, often other people inquired or require that other people make an explanation repeatedly tirelessly or ensure.

3. mandatory cleaning: be subject to worry that antibacterial or booty pollute to eliminate and repeated multiple times wash one's hands, have a bath or wash clothes.Some patients are repeated multiple times to wash one's hands with soap, and unanimously causes skin of dorsum of hand to chap or breakage, but still so repeatedly washes one's hands, otherwise there will be very serious anxiety or worry.

4. mandatory consciousness action: refer to that patient completes a series of compound action behavior or repeats some action, to eliminate or to alleviate the anxiety or uneasiness that are caused by obsessive idea.As two steps of must first advancing when patient gos out, and then backward backward, so repeatedly do and just can go out for several times.Someone is also included into this type of compulsive counting.Some patient causes being slow in action because of mandatory consciousness action, such as morning WA, repeatedly wear off clothes repeatedly, till patient oneself pleases oneself, so just stopped over the time, unanimously to delay work or late.

Many researcheres inquire into the origin cause of formation of this phenomenon respectively from number of ways such as neural biochemistry, hereditism and psychology, have several main hypothesis.

One, psychoanalytic theory: Freud thinks that obsession is further developing of the obsessive-compulsive personality of pathology, is the anxiety formed because defense mechanism can not process obsessive-compulsive personality, so create mandatory symptom.

Two, trained reflex: the pathological inertress focus of excitation that Pavlov isolates with cerebral cortex is to explain the physiological mechanism of this disease.

Three, quality particularly premorbid personality play an important role in the primary disease cause of disease: namely have obsessive-compulsive personality or psychasthenia before the obsession patient disease of about 2/3.Its main manifestations is: the tight control trying hard to keep self and environment, they pay attention to detail, and do anything and all make every effort to accurate, perfect, but even so also still have the sensation of " imperfection ", " dangerous " and " uncertain ".They or show as and follow the beaten track, lack resolution, irresolute, dependence is obedient to; Or show as stubborn stubborn, stick to the established practice, would rather break than bend and short-tempered.

Four, socio-psychological factors is the important risk factor of obsession: such as due to the transition of work, living environment, responsibility increases the weight of, and is in a predicament, and worries unexpected, family's discord or owing to losing relatives, is subject to unexpected scaring etc.Some normal person also has obsessive idea once in a while but does not continue, but can be reinforced and sustainable existence under Thinking of Social Factors Influence, thus forms obsession.

Five, heredity occurs to play a role at primary disease: in the father and mother of such as patient, compulsive prevalence is 5%-7%, more much higher than the sickness rate of colony.The compatriot of patient, father and mother and children, belong to obsessive-compulsive personality person also more.

Six, Biochemical Research: prompting 5-hydroxy tryptamine (5-HT) systemic-function strengthens falls ill relevant with this disease, and therefore 5-HT reuptake inhibitor is as Clomipramine, Fluaxetine and Clovoxamine etc., all has good curative effect to obsession.Linkage relationship is there is in this disease of other research prompting with the morbidity of depression, as this disease patient has 25%-40% not suppress dexamethasone Inhibition test (DST), some patients polysomnogram display rapid-eye-movement sleep (REM) shorter latencies etc.}

Two, Therapeutic Method

1. the treatment of psychodynamics

The treatment of psychological force school is emphasized by insight, is changed emotion experience and strengthen self-method and go to analyze and explain the contradiction between various psychological phenomenon, reaches the object for the treatment of with this.In the process for the treatment of, use explaination in large quantities, analysiss of shifting one's love, self-to associate and self-reconstruction technique.

2. behavior therapy

For in compulsive understanding, behavior therapy is divided into two basic schools.The first viewpoint think have compulsive people be by means of various actions and ceremonial to alleviate anxiety, be called " drive reduces model ".According to this model, therapist mainly concentrates on by exciting the situation that can reduce anxiety to eliminate improper department and ceremonial.The second viewpoint is set up based on operation model, emphasizes to regulate compulsive consequence, and therefore a large amount of utilization is punished and demonstration study in this model.

3, western modern medicine treatment

Western modern medicine treatment obsession mainly adopts 5-hydroxy tryptamine (5-HT) class medicine in the world at present.5-HT reuptake inhibitor, as Clomipramine, Fluaxetine and fluvoxamine etc., all has good curative effect to obsession.But side effect is comparatively large, and long-term taking has a lot of impact to the function such as liver, kidney.

4, treatment by Chinese herbs

Compulsive treatment by Chinese herbs has no side effect to health, and rehabilitation efficacy is obvious.Treatment by Chinese herbs, compared with western medicine obsession, has the advantage of oneself uniqueness.Determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is emphasized in Chinese traditional treatment, and first the traditional Chinese medical science will distinguish deficiency and excess to obsession, then selects different square medicines to treat respectively.The traditional Chinese medical science is mainly according to its clinical manifestation, and determination of cause of disease according to differentiation of symptoms and signs, examine because opinion is controlled, the present invention is pure compound Chinese medicinal preparation, and long-term use and have small side effects, and drug effect is rapid, dosage is accurate, reliable effect.The batch production of this product has good market potential, the market demand.And this product is in my institute's clinical practice for many years, evident in efficacy, the dark welcome by patient.Through the relevant further investigation of the systems such as clinical pharmacology, after condition maturity, new Chinese medicine will be declared, for this sick increase new force is treated by China.

The present invention is mainly for treatment obsession hepatic depression combined symptoms type.

(3), summary of the invention

It is good that the object of the invention is to provide a kind of therapeutic effect, the compulsive Chinese medicine preparation for the treatment of that side effect is little.

The object of the present invention is achieved like this: according to weight portion be: Bulbus Lilii 30-80 part, Fructus Corni 60-90 part, Rhizoma Curculiginis 80-120 part, Radix Rehmanniae 10-50 part, Os Draconis 10-50 part, Concha Ostreae 10-50 part, Radix Polygalae 10-40 part, Radix Ophiopogonis 10-35 part, Fructus Schisandrae Chinensis 5-30 part, Poria 10-50 part, Pericarpium Citri Reticulatae 10-30 part, Chuan Bi Collettii 60-85 part, Semen sesami Niger 60-90 part, Herba Cynomorii 60-90 part, Radix Glycyrrhizae 5-30 part, Caulis Bambusae In Taenia 10-35 part, Radix Salviae Miltiorrhizae 100-200 part, Succus Bambusae 5-20 part ratio, each raw material is mixed into powder and makes.

Adopt the present invention to carry out clinical observation test in the neural section hospital of Heilungkiang Kang Yuan, now model case be described below:

Case 1, Zhu, man, 15 years old, Daqing Middle School Students.Teacher arranges operation, his always verification repeatedly, and seen and also worried again and again, in fact oneself also know it is that these exercise questions are quite right, can be exactly do not stop, that loses control of checks.After finishing operation, also will inspection repeatedly, the inspection of a word word, it is no problem in fact oneself also to know.He says that in life, there is such a case, does not always believe oneself ready-made thing, checked ability is relieved repeatedly, to oneself bringing great misery.But what this custom that he hates oneself especially, because this wastes his too many time, does all inefficent, he attempts to make great efforts to control, but controls more painful uneasiness.Patient came my institute and went to a doctor in April, 2009.After diagnosing, these middle school student suffer from obsession, take Chinese medicine of the present invention and treat, and the obsessive symptoms that after two courses for the treatment of, these middle school student are all obviously alleviates.Continuous treatment six months, symptom disappears substantially.

Case 2, Lee, man, 30 years old, Han nationality, Harbin City university student.Patient because the large appearance of learning pressure checks a certain thing repeatedly, knew perfectly well and settles before 2 years, but worried, repeatedly checked, until relieved.Know obviously that these ideas derive from oneself, but oneself effectively can not control, want to control just to lose control of, therefore feel very painful.Many the hospital admissions in Harbin, are diagnosed as obsession subsequently.And take the western medicines such as alprazolam, symptom slightly alleviates.Recent patient's symptom increases the weight of again, and in July, 2008 comes my institute and seeks medical advice.Sign on inspection, after the psychiatric department specialties such as row DNR check, clarifies a diagnosis as " obsession ".Treatment gives therapy of combining Chinese and Western medicine, gives our hospital Chinese medicine preparation of the present invention oral simultaneously.And coordinate the psychology such as work and recreational therapy auxiliary.Through a course for the treatment of of above-mentioned treatment, patients symptomatic improves obviously, continues the above-mentioned treatment of row, and after 3 courses for the treatment of of treatment, obsessive symptoms disappears substantially.Now complete university's school work.

Case 3, Cai so-and-so, female, 22 years old.Daqing, Heilongjiang Province university student.Be conscientious in one's work from little, sense of personal worth is strong, introverted, and school grade is also good, and occurred the thing always repeatedly checked in school bag the year before, repeatedly check after finishing operation, be deeply afraid to do sth wrong, walking also looks back at repeatedly, is afraid of that what has fallen.Father and mother deliberately say her, these symptoms are more obvious, always lose control of oneself.Become at leisure and feel bad, very anxiety, sometimes gratuitous and others noisy frame, classmate's strained relations, school grade declines obviously.Certain hospital diagnosis is obsession, takes western medicine, because side effect is very large, always sleepy, and brains all day unsuspectingly unclear, have impact on study, just stopped Western medicine.In JIUYUE, 2008 carrys out my institute's treatment, and my institute is to taking Chinese medicine of the present invention, and after the course for the treatment of, symptom alleviates.After three courses for the treatment of, symptom alleviates more than 90 percent.Treat three months again, symptom disappears substantially, and anxiety is alleviated a lot, and sleep have also been obtained very large improvement.Follow up a case by regular visits to so far, the mental status is fine, and school grade improves.

Case 4, Bing so-and-so, male, 48 years old, Harbin City company car driver.The unsociable and eccentric introversion of patient, certain camera lens occurred inside TV play repeatedly will be thought during children, along with growing up slowly, just have following morbid psychology as: know that electric light contact is easily leaked electricity danger close perfectly well, also go to touch with hands, handle burns terribly sometimes, but also wants next time to get an electric shock, be difficult to control, load is feared again very much.Very contradiction is painful at heart.Insomnia is serious, sentimentality, be reluctant to contact with people, in July, 2008, household was with it to carry out institute's medication treatment, reflected that this type of symptom obviously alleviates after taking Chinese medicine two weeks of the present invention, electricity is touched in after treatment idea after 3 courses for the treatment of is improved greatly, treat after six months, do not want to touch electricity, misery at heart also alleviates many, normal working, does not recur again now.

Case 5, the Meng so-and-so, female, 45 years old, Harbin City's Cadres of Enterprises.Whether, have a hunch hands clean, at every turn go out all can verification repeatedly lock a door, sometimes walked far also will return check, but each result is all door locks if there is washing one's hands repeatedly before 5 years in patient.At home, coal gas has been closed in checking whether repeatedly, sometimes coal gas is reopened and shuts, and patient obviously knows that these all there is no need but are difficult to control at heart.Over nearly 5 months, symptom obviously increases the weight of, and almost washes one's hands every day tens times, has a bath more than 4 hours at every turn, again and again will check that Men Caike is relieved several times when going out.Go out to go home by bus all clothes to be changed, oneself also will be washed hair, have a bath a few hours, worries to have soil, and worrying can do by myself is gone down with.Meanwhile, also often require that household washes repeatedly, do anything and all want a left side to see that the right side is seen, action is obviously slow, and repeatedly checks that multipass just can be relieved.Patient feels very painful.Patient once treated at certain large hospital, DeGrain.Again and again, patient almost will be desperate for symptom.In JIUYUE, 2008, by website, patient learns that my institute's treatment obsession curative effect is very good, and be pure treatment by Chinese herbs, and have no side effect, prognosis is not recurred, and patient comes my institute's treatment.Be diagnosed as obsession.Use treatment by Chinese herbs of the present invention three weeks, patient's obsessive idea alleviates to some extent, and number of times of washing one's hands also reduces gradually, and therapeutic effect clearly.After disease amelioration, adjustment therapeutic regimen, treated with patients ' psychological, symptom alleviates further simultaneously.After consolidating treatment in four months, patient's obsession is cured completely, and patient has gone up again the life of normal person excessively.

Case 6, ancestor so-and-so, male, 34 years old, Harbin City laid-off worker.Personality just compares and seeks to prevail over others at an early age, requires harsh to oneself.Over one year, after going out every day, total worry does not lock door and returns and checks, always think do-it-yourself what all do not carry out, repeatedly do same thing, to oneself self-distrust, worry that self-made thing can be made mistakes or hurt others, walk that always feel on road will on road limit, want to draw oneself up, but lose control of, be sorely distressed at heart.Check at Harbin Medical University's department of neurology, do Cranial Computed Tomography no abnormality seen.Department of neurology checks also no abnormality seen pathologic sign.In February, 2009, my institute sought medical advice.My institute is diagnosed as obsession.Take treatment by Chinese herbs of the present invention.After the course for the treatment of, symptom improves 40 about percent.Worry that the number of times of locking a door decreases, after taking two courses for the treatment of, symptom disappears substantially.Take 1 year, substantially no longer include now inspection and lock a door, close the thing of window, also normal when walking.

(4), detailed description of the invention

The present invention is that one treats compulsive Chinese medicine preparation, for a more detailed description to the present invention below, according to weight portion be: Bulbus Lilii 30-80 part, Fructus Corni 60-90 part, Rhizoma Curculiginis 80-120 part, Radix Rehmanniae 10-50 part, Os Draconis 10-50 part, Concha Ostreae 10-50 part, Radix Polygalae 10-40 part, Radix Ophiopogonis 10-35 part, Fructus Schisandrae Chinensis 5-30 part, Poria 10-50 part, Pericarpium Citri Reticulatae 10-30 part, Chuan Bi Collettii 60-85 part, Semen sesami Niger 60-90 part, Herba Cynomorii 60-90 part, Radix Glycyrrhizae 5-30 part, Caulis Bambusae In Taenia 10-35 part, Radix Salviae Miltiorrhizae 100-200 part, Succus Bambusae 5-20 part ratio, each raw material is mixed into powder and makes.

Claims (1)

1. treat a compulsive Chinese medicine preparation, it is characterized in that: according to weight portion be: Bulbus Lilii 30-80 part, Fructus Corni 60-90 part, Rhizoma Curculiginis 80-120 part, Radix Rehmanniae 10-50 part, Os Draconis 10-50 part, Concha Ostreae 10-50 part, Radix Polygalae 10-40 part, Radix Ophiopogonis 10-35 part, Fructus Schisandrae Chinensis 5-30 part, Poria 10-50 part, Pericarpium Citri Reticulatae 10-30 part, river numbness Collettii 60-85 part, Semen sesami Niger 60-90 part, Herba Cynomorii 60-90 part, Radix Glycyrrhizae 5-30 part, Caulis Bambusae In Taenia 10-35 part, Radix Salviae Miltiorrhizae 100-200 part, Succus Bambusae 5-20 part ratio each raw material be mixed into powder make.。