CN104857099A - Oral medicine for treating raynaud's syndrome and preparation method of oral medicine - Google Patents

Abstract

The invention provides an oral medicine for treating raynaud's syndrome and a preparation method of the oral medicine. The oral medicine comprises components in parts by mass as follows: 1-3 parts of astragalus membranaceus, 1-3 parts of Chinese angelica, 1-3 parts of prepared lateral roots of aconite, 1-3 parts of cassia barks, 1-3 parts of danshen roots, 1-3 parts of mulberry twigs, 1-3 parts of suberect spatholobus stem, 1-3 parts of manchurian wildginger, 1-3 parts of red paeony roots and 1-3 parts of cassia twigs. The preparation method of the oral medicine comprises steps as follows: high-quality and first-grade astragalus membranaceus, Chinese angelica, prepared lateral root of aconite, cassia barks, danshen roots, mulberry twigs, suberect spatholobus stem, manchurian wildginger, red paeony roots and cassia twigs are purchased in parts by mass; impurities and dust in the raw materials are removed and then put into a medicine bag, and an opening of the medicine bag is tied for standby; the medicines are put into cooled boiled water to be soaked for about half an hour until the medicine tissue is thoroughly soaked, then the soaked medicines and clear liquor for soaking the medicines are put into a medicine decoction machine, cooled boiled water is added until the water level is 33 mm higher than the medicines, the medicines are decocted twice and decocted for 30 minutes for the first time, after liquid medicine is filtered, medium-temperature boiled water is added until the water level is 30 mm higher than the medicines, the medicines are decocted for 25 minutes for the second time, then the clear liquor is mixed and condensed to form 1800 mm of a 50% traditional Chinese medicine liquid, and the 50% traditional Chinese medicine liquid is put into a refrigerator for standby after bagged and sealed.

Description

A kind of endo-medicine for the treatment of Raynaud's syndrome and preparation method thereof

Technical field

The present invention relates to technical field of Chinese medicines, be specifically related to a kind of endo-medicine for the treatment of Raynaud's syndrome, particularly for the field of the endo-medicine and preparation method thereof of Raynaud's syndrome patient.

Background technology

Show according to medical literature: Raynaud's syndrome be due to cold or excited cause the finger of outbreak (toes) pale, blue after transfer one group of syndrome of flushing to, special reason person is not had to be called idiopathic Raynaud syndrome, the person that is secondary to other diseases, be then called Secondary cases Raynaud syndrome.This disease mostly occurs at 20 ~ 40 years old, and women is more than male, and onset is slow, and start as winter attack, the time is shorter, shows effect when engendering and meet cold or excited, and mostly generally be the outbreak of symmetry both hands finger, toes also can occur.During outbreak, brothers are cold, numbness, occasionally has pain, during Typical onset, take metacarpophalangeal joints as boundary, finger is sent out cool, pale, blue, flushing then, the terminal stage of a disease, engenders that dorsal surfaces of fingers fine hair disappears, nail growth is slack-off, coarse, distortion, atrophoderma is thinning and feel nervous (scleroderma refers to), forms ulcer around finger tip or nail matrix, and can cause infection.

So, just how finding a kind of medicine effectively can treating above-mentioned Raynaud's syndrome, is our current problem in urgent need to solve.

Summary of the invention

The object of this invention is to provide a kind of endo-medicine for the treatment of Raynaud's syndrome and preparation method thereof, to solve Raynaud's syndrome patient restorative problem early.This medicine is that have compatibility reasonable, the efficacy of a drug is powerful, hit pathogenesis, has fully demonstrated benefiting QI for activating blood circulation, relieving spasm to stop pain, helps the Therapeutic Principle with warming kidney for dispelling cold with common Chinese herbal medicine for raw material.

For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of endo-medicine for the treatment of Raynaud's syndrome and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Astragali 1-3 part;

Radix Angelicae Sinensis 1-3 part;

Radix Aconiti Lateralis Preparata sheet 1-3 part;

Cortex Cinnamomi 1-3 part;

Radix Salviae Miltiorrhizae 1-3 part;

Ramulus Mori 1-3 part;

Caulis Spatholobi 1-3 part;

Herba Asari 1-3 part;

Radix Paeoniae Rubra 1-3 part;

Ramulus Cinnamomi 1-3 part.

According to the endo-medicine for the treatment of Raynaud's syndrome provided by the present invention, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

The Radix Astragali 1 part;

Radix Angelicae Sinensis 1 part;

Radix Aconiti Lateralis Preparata sheet 1 part;

Cortex Cinnamomi 1 part;

Radix Salviae Miltiorrhizae 1 part;

Ramulus Mori 1 part;

Caulis Spatholobi 1 part;

Herba Asari 1 part;

Radix Paeoniae Rubra 1 part;

Ramulus Cinnamomi 1 part.

A kind of endo-medicine for the treatment of Raynaud's syndrome and preparation method thereof, is characterized in that, described method comprises the steps:

A, choose the clean one-level Radix Astragali of high-quality 1 part, Radix Angelicae Sinensis 1 part, Radix Aconiti Lateralis Preparata sheet 1 part, Cortex Cinnamomi 1 part, Radix Salviae Miltiorrhizae 1 part, Ramulus Mori 1 part, Caulis Spatholobi 1 part, Herba Asari 1 part, Radix Paeoniae Rubra 1 part, Ramulus Cinnamomi 1 part, enter tying in medicated bag after picking decontamination and dust respectively stand-by;

B, said medicine put into about cold boiled water soaks half an hour, to soak into drug entities for degree, then again the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, injected fried twice of the cold boiled water of medicine 33mm, fried 30 minutes of first time, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 30mm carries out second time fried 25 minutes, mixing is condensed into the herb liquid 1800 milliliters of 50%, enters fridge freshness retaining for subsequent use after pack sealing.

A kind of endo-medicine for the treatment of Raynaud's syndrome and preparation method thereof, is characterized in that, described instructions of taking is: divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 200 milliliters/time, taking medicine before meal.Take medicine after 230-250 agent, all diseases disappear substantially, can normally go to work.

Medicine provided by the present invention is oral traditional Chinese medicine composition, and it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:

The Radix Astragali, nature and flavor: sweet, warm, there is effect of invigorating QI to consolidate the body surface resistance, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation,, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis weak for the deficiency of vital energy, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty are burst, burst for a long time do not hold back, blood deficiency dull yellowish colored skin, interior-heat quench one's thirst, chronic nephritis, albuminuria, diabetes;

Radix Angelicae Sinensis, nature and flavor:, warm in nature, sweet in the mouth is pungent, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, for blood deficiency, shallow complexion, dizzy cardiopalmus, blood deficiency or have the pain cards such as the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, angina pectoris, rheumatic arthralgia, traumatic injury concurrently;

Radix Aconiti Lateralis Preparata sheet, nature and flavor: pungent, sweet, hot greatly, poisonous, there is recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by effect of wind-cold damp pathogen, for YANG-depletion collapse, the vomiting and diarrhoea of cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes;

Cortex Cinnamomi, nature and flavor: extremely hot in nature, acrid in the mouth, sweet, have and mend that fire is supporing yang, effect of let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, for sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea;

Radix Salviae Miltiorrhizae, nature and flavor: bitter, be slightly cold, there is effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind, swell and ache for menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection, dysphoria and insomnia, hepatosplenomegaly, the disease such as angina pectoris;

Ramulus Mori, nature and flavor: micro-hardship, flat, have effect of wind-damp dispelling, the meridian dredging, row aqueous vapor, for rheumatic arthralgia, apoplexy and hemiplegia, edema beriberi, human body pruritus due to wind pathogen;

Caulis Spatholobi, nature and flavor: bitter in the mouth, micro-sweet, warm in nature, have effect of relaxing muscles and tendons to promote blood circulation, nourishing blood for regulating menstruation, have through uncomfortable, dysmenorrhea, amenorrhea for numb hand and foot, quadriplegia, rheumatic arthralgia, women;

Herba Asari, the property of medicine: pungent, warm, slightly poisonous, have that cold expelling dispels the wind, pain relieving, warming the lung to resolve fluid-retention, sensible, the effect of inducing sweat, for exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia, phlegm retention cough with asthma, nasal obstruction, nasal sinusitis, aphtha;

Radix Paeoniae Rubra, nature and flavor: bitter, be slightly cold, have effect of clearing away heat and cooling blood, eliminating stasis to stop pain, for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection;

Ramulus Cinnamomi, nature and flavor: pungent, sweet, warm in nature, have effect of expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, short yang transforming qi, for exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea, mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria.

When taking, divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 200 milliliters/time, taking medicine before meal.Take medicine after 230-250 agent, all diseases disappear substantially, can normally go to work.This medicine is that have compatibility reasonable, the efficacy of a drug is powerful, hit pathogenesis, has fully demonstrated benefiting QI for activating blood circulation, relieving spasm to stop pain, helps the Therapeutic Principle with warming kidney for dispelling cold with common Chinese herbal medicine for raw material.

Detailed description of the invention

Below embodiments of the present invention are described in detail

Raynaud's syndrome be due to cold or excited cause the finger of outbreak (toes) pale, blue after transfer one group of syndrome of flushing to, special reason person is not had to be called idiopathic Raynaud syndrome, the person that is secondary to other diseases, be then called Secondary cases Raynaud syndrome.This disease mostly occurs at 20 ~ 40 years old, and women is more than male, and onset is slow, and start as winter attack, the time is shorter, shows effect when engendering and meet cold or excited, and mostly generally be the outbreak of symmetry both hands finger, toes also can occur.During outbreak, brothers are cold, numbness, occasionally has pain, during Typical onset, take metacarpophalangeal joints as boundary, finger is sent out cool, pale, blue, flushing then, the terminal stage of a disease, engenders that dorsal surfaces of fingers fine hair disappears, nail growth is slack-off, coarse, distortion, atrophoderma is thinning and feel nervous (scleroderma refers to), forms ulcer around finger tip or nail matrix, and can cause infection.

The present invention is exactly treatment for above-mentioned Raynaud's syndrome and a kind of Chinese herbal medicine formula proposed, and the herb liquid adopting this formula to prepare or powder, good drug efficacy, instant effect, toxic and side effects is little, effectively can treat Raynaud's syndrome.Below specific embodiment provided by the present invention is described in detail.

Embodiment 1:

Choose the clean one-level Radix Astragali of high-quality 30 grams, Radix Angelicae Sinensis 10 grams, Radix Aconiti Lateralis Preparata sheet 9 grams, Cortex Cinnamomi 9 grams, Radix Salviae Miltiorrhizae 15 grams, Ramulus Mori 30 grams, Caulis Spatholobi 10 grams, Herba Asari 9 grams, Radix Paeoniae Rubra 10 grams, Ramulus Cinnamomi 9 grams, enter tying in medicated bag after picking decontamination and dust respectively stand-by; Said medicine is put into about cold boiled water soaks half an hour, to soak into drug entities for degree, then again the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, injected fried twice of the cold boiled water of medicine 33mm, fried 30 minutes of first time, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 30mm carries out second time fried 25 minutes, mixing is condensed into the herb liquid 1800 milliliters of 50%, enters fridge freshness retaining for subsequent use after pack sealing.When taking, divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 200 milliliters/time, taking medicine before meal.Take medicine after 230-250 agent, all diseases disappear substantially, can normally go to work.

Embodiment 2:

Choose the clean one-level Radix Astragali of high-quality 33 grams, Radix Angelicae Sinensis 11 grams, Radix Aconiti Lateralis Preparata sheet 9 grams, Cortex Cinnamomi 10 grams, Radix Salviae Miltiorrhizae 17 grams, Ramulus Mori 33 grams, Caulis Spatholobi 11 grams, Herba Asari 9 grams, Radix Paeoniae Rubra 11 grams, Ramulus Cinnamomi 10 grams, enter tying in medicated bag after picking decontamination and dust respectively stand-by; Said medicine is put into about cold boiled water soaks half an hour, to soak into drug entities for degree, then again the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, injected fried twice of the cold boiled water of medicine 33mm, fried 30 minutes of first time, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 30mm carries out second time fried 25 minutes, mixing is condensed into the herb liquid 1800 milliliters of 50%, enters fridge freshness retaining for subsequent use after pack sealing.When taking, divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 200 milliliters/time, taking medicine before meal.Take medicine after 230-235 agent, all diseases disappear substantially, can normally go to work.

Embodiment 3:

Choose the clean one-level Radix Astragali of high-quality 30 grams, Radix Angelicae Sinensis 10 grams, Radix Aconiti Lateralis Preparata sheet 9 grams, Cortex Cinnamomi 9 grams, Radix Salviae Miltiorrhizae 15 grams, Ramulus Mori 30 grams, Caulis Spatholobi 10 grams, Herba Asari 9 grams, Radix Paeoniae Rubra 10 grams, Ramulus Cinnamomi 9 grams, enter tying in medicated bag after picking decontamination and dust respectively stand-by; Said medicine is put into about cold boiled water soaks half an hour, to soak into drug entities for degree, then again the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, injected fried twice of the cold boiled water of medicine 33mm, fried 30 minutes of first time, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 30mm carries out second time fried 25 minutes, mixing is condensed into the herb liquid 1800 milliliters of 50%, enters fridge freshness retaining for subsequent use after pack sealing.When taking, divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 200 milliliters/time, taking medicine before meal.Take medicine after 230-240 agent, all diseases disappear substantially, can normally go to work.

The present invention is through the treatment to nearly one hundred routine patient, and therapeutic effect is remarkable, and toxic and side effects is little, and part allusion quotation shape case is as follows.

1, patient: clock XX, female, 40 years old, address: Zhongjiang County, Sichuan Province

Illness symptom: patient is in JIUYUE in 1992 first visit on the 20th.After within its 1988, suffering from " hyperthyroidism " and artificial abortion, Mental fatigue body is stranded, and press treatment for anemia invalid always, and within 1989, namely feeling two upper arm to finger end, to send out cool hardening, bad during fashion, facial and two hands edema yellow skin during outbreak, pain.In county's hospitalize, make a definite diagnosis.Annual autumn and winter, cold water is washed one's hands and after fatigue, exacerbation of symptoms, and feel numb, summer is alleviated, and meets warm alleviating, since the several years, through Chinese and western medical and acupuncture and moxibustion therapy invalid.Day is seriously ashamed, affects work.Go to work half an hour, feel fatigue and can't bear, point underaction when writing, frequent dizzy Mental fatigue, eats poor appetite less, and menstruation is rare light, irascible temperament, and pulse condition is heavy thin, and the tip of the tongue limit is red, yellow and thin fur.Card belongs to deficiency of spleen-YANG and kidneyYANG, blood deficiency cold coagulation.The rule for the treatment of: warming kidney for dispelling cold, nourishing blood and promoting blood circulation.

Treatment: throw top " herb liquid or powder " plus-minus and control it, every day potion, and by FUFANG DANSHEN ZHUSHEYE, once a day, each intramuscular injection.After taking medicine, upper and lower extremities muscle comparatively before soft, action is slightly flexible, and finger yellow disappears, and meets cold still acroanesthesia and pain.Arteries and veins tongue is the same, and former side adds Pheretima 9 grams, takes medicine 10 doses.Skin is limbered up by coarse, and face and hands Huang disappear, and the whole body is dispersed in blue patch and takes a turn for the better.Take medicine 39 doses altogether, greatly, pain obviously alleviates for existing forearm and finger flexibility ratio, but still sense upper limb feels cold, poor appetite, body is stranded, and arteries and veins tongue is the same, and because medicine difficulty is purchased in mountain area, decoction is not too convenient, after by top altogether levigation agent, every day 3 times, take after mixing it with water for each 2 grams, and advise and adhere to long-term taking.Through nearly 8 months adhere to medication, except change in weather, slightly outside discomfort, all symptoms disappear substantially, can normally go to work.

2, patient: Du XX, female, 35 years old, address: Xinjin County, Sichuan Province

Illness symptom: patient once suffered from hyperthyroidism and artificial abortion, Mental fatigue body is stranded, and it is invalid once press the treatment for anemia a few days, and namely feeling both arms to finger end afterwards, to send out cool hardening, bad during fashion, facial and two hands edema yellow skin during outbreak, pain.In city's hospitalize, make a definite diagnosis.Annual autumn and winter, cold water is washed one's hands and after fatigue, exacerbation of symptoms, and feel numb, summer is alleviated, and meets warm alleviating, since the several years, through Chinese and western medical and acupuncture and moxibustion therapy invalid.Day is seriously ashamed, affects work.Go to work half an hour, feel fatigue and can't bear, frequent dizzy Mental fatigue, food of receiving is poor, and menstruation is rare light, irascible temperament, and pulse condition is heavy thin, and the tip of the tongue limit is red, yellow and thin fur.

Treat: throw top " herb liquid or powder " plus-minus and control it, every day, potion, also used FUFANG DANSHEN ZHUSHEYE simultaneously, once a day, and each intramuscular injection.After taking medicine, upper and lower extremities muscle comparatively before soft, action is slightly flexible, and finger yellow disappears, and meets cold still acroanesthesia and pain.Arteries and veins tongue is the same, and former side adds Pheretima 8 grams, takes medicine 12 doses.Skin is limbered up by coarse, and face and hands yellow showing disappear, and the whole body is dispersed in blue patch and takes a turn for the better.Take medicine 42 doses altogether, forearm and finger flexibility ratio large, pain obviously alleviates, but still sense upper limb feels cold, poor appetite, and body is stranded, and arteries and veins tongue is the same, and owing to purchasing medicine difficulty, decoction is not too convenient, after by top levigation agent altogether, every day 3 times, take after mixing it with water for each 2 grams, and advise and adhere to long-term taking.Through more than 8 months adhere to medication, all diseases disappear substantially, can adhere to working.

Claims (3)

1. treat an endo-medicine for Raynaud's syndrome, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Astragali 1-3 part;

Radix Angelicae Sinensis 1-3 part;

Radix Aconiti Lateralis Preparata sheet 1-3 part;

Cortex Cinnamomi 1-3 part;

Radix Salviae Miltiorrhizae 1-3 part;

Ramulus Mori 1-3 part;

Caulis Spatholobi 1-3 part;

Herba Asari 1-3 part;

Radix Paeoniae Rubra 1-3 part;

Ramulus Cinnamomi 1-3 part.

2. the endo-medicine for the treatment of Raynaud's syndrome according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

The Radix Astragali 1 part;

Radix Angelicae Sinensis 1 part;

Radix Aconiti Lateralis Preparata sheet 1 part;

Cortex Cinnamomi 1 part;

Radix Salviae Miltiorrhizae 1 part;

Ramulus Mori 1 part;

Caulis Spatholobi 1 part;

Herba Asari 1 part;

Radix Paeoniae Rubra 1 part;

Ramulus Cinnamomi 1 part.

3. endo-medicine of the treatment Raynaud's syndrome described in a claim 1 or 2 and preparation method thereof, is characterized in that, described method comprises the steps:

According to mass parts than choosing the clean one-level Radix Astragali of high-quality, Radix Angelicae Sinensis, Radix Aconiti Lateralis Preparata sheet, Cortex Cinnamomi, Radix Salviae Miltiorrhizae, Ramulus Mori, Caulis Spatholobi, Herba Asari, Radix Paeoniae Rubra, Ramulus Cinnamomi, enter tying in medicated bag after picking decontamination and dust respectively stand-by;

B, said medicine put into about cold boiled water soaks half an hour, to soak into drug entities for degree, then again the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, injected fried twice of the cold boiled water of medicine 33mm, fried 30 minutes of first time, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 30mm carries out second time fried 25 minutes, mixing is condensed into the herb liquid 1800 milliliters of 50%, enters fridge freshness retaining for subsequent use after pack sealing.