CN104856651A - Using method for red-free radiography equipment - Google Patents
Using method for red-free radiography equipment Download PDFInfo
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- CN104856651A CN104856651A CN201510245848.5A CN201510245848A CN104856651A CN 104856651 A CN104856651 A CN 104856651A CN 201510245848 A CN201510245848 A CN 201510245848A CN 104856651 A CN104856651 A CN 104856651A
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Abstract
The invention belongs to the field of medical detection equipment and particularly relates to radiography equipment. The radiography equipment is characterized in that conventional FA examination is carried out on the radiography equipment, the excitation wavelength is 488 nm, the emission wavelength is 500 nm, the image resolution is 768*768 pixels, the coloring agent is fluorescein sodium, the shooting angle of a shooting lens is 30 degrees or 55 degrees, and an optical filter is arranged under the lens; after the FA venous phase, a detection mode is converted into a red-free mode RF fast, at the moment, the optical filter is removed, and the equipment records more reflection light; red-free angiography carried out under the same FA parameters is RFA. By the implementation of the technical scheme, the definition of equipment imaging can be improved, and clearer imaging background information is obtained.
Description
Technical field: the invention belongs to Medical Equipment field, particularly relates to a kind of contrast apparatus.
Background technology: fluorescein angiographic (FA) is based on the blue laser technology of argon, and emission wavelength is 488nm, and optical filter is 500nm, acts on fluorescein sodium dyestuff.This technology can obtain high-quality fundus photography, and display has retinal vascular morphologies and the dyestuff seepage of high-contrast.In radiography testing process before this, all can there is following several situation:
1, in FA, 500nm optical filter have lost part retina background information;
2, unclear to shallow table membranous structure display;
3, owe clear for the display of retinal vessel level.
Summary of the invention:
Goal of the invention: the invention provides a kind of using method without red smooth contrast apparatus, its object is to the definition of raising equipment imaging, obtains imaging background information more clearly, and display has the image of high-contrast.
Technical scheme: the present invention is achieved through the following technical solutions:
Without a using method for red smooth contrast apparatus, it is characterized in that: the method is carried out in accordance with the following steps:
(1). first carry out conventional FA inspection to contrast apparatus, that is: excitation wavelength: 488nm, emission wavelength: 500nm, image resolution ratio 768*768 pixel, stain: fluorescein sodium, pick-up lens shooting angle 30 ° or 55 °, camera lens has optical filter;
(2), after .FA venous phase, be converted to by detecting pattern without red optical mode RF rapidly, now optical filter is removed, and equipment have recorded more reflected light;
(3). carry out under FA identical parameters without red smooth angiography, be RFA.
In step (2), after FA venous phase, be converted to by detecting pattern without red optical mode RF in 2 ~ 3 seconds, optical filter removes.
Described contrast apparatus is retinal vessel radiography and the OCT of the production of Heidelberg, Germany company.
The radiography that the method can be applicable to other organs except eye ground detects detects.
Advantage and effect: by the enforcement of the technical program, can improve the definition of equipment imaging, obtains imaging background information more clearly, and display has the image of high-contrast.
Detailed description of the invention:
Utilize confocal scanning laser ophthalmoscope (CSLO) row blue light namely without red smooth angiography (RFA), fluorescein angiographic (FA) is based on the blue laser technology of argon, emission wavelength is 488nm, and optical filter is 500nm, acts on fluorescein sodium dyestuff.This technology can obtain high-quality fundus photography, and display has retinal vascular morphologies and the dyestuff seepage of high-contrast.And apply optical filter, FA technology can miss many focuses.Contrast with FA, it is the laser of 488nm that blue light (without red light, RF) only needs a Solid State Laser to produce excitation wavelength, does not have optical filter.
The Spectralis retinal vessel radiography that application Heidelberg, Germany company produces and OCT (HRA+OCT), conventional row fluorescence fundus angiography (fluorescein angiography, FA, exciting light 488nm, optical filter 500nm, dyestuff: fluorescein sodium), after venous phase, detecting pattern is converted to without red light (RF by (2 ?3 seconds in) rapidly, exciting light 488nm), (ART>16 frame under FA parameter before, B scanogram quality is more than 16) carry out without red smooth angiographic image collection, be RFA.
After FA venous phase, the detecting pattern of angiographic instrument is converted to without red light (RF) pattern from FA by (2-3 is interior for second) rapidly, carries out angiography, can obtain without red smooth shadowgraph technique (RFA) under the same parameter of FA.It should be noted that and there will be a white bright spot in RFA picture centre portion, is optical reflection artifact.
Compared with traditional F A, RFA can clear display optic disc, sieve plate form, and visible optic disc peripheral retinal tear nerve fibre layer staining conditions.Compared with the highlighted development of retinal vessel in FA, the stereochemical structure of visible retinal vessel in RFA, in addition, RFA can show detached macula scope, and traditional F A can not; See the examination as to substances reference material of the application.
In addition, due to the Absorption of retina trunk, RFA can the border of clear display retina trunk.In addition due to hemoglobin, retina coloured groups, the absorptance of retinal pigment and other retinal tissues is different, is all RFA high definition reason.This research can be used as the strong of traditional F A and supplements.
RFA utilizes stable, solid laser to produce single wavelength scanning laser (488nm), provides the high quality graphic more stablizing wide area.By contrast, the specific narrow image (exciting light 488nm, optical filter 500nm) that FA produces, causes parts of images information loss.Compared with FA, RFA is more clear demonstrates optic disc and sieve-plate structure, and dyestuff can be utilized clearly to detect retinal nerve fibre layer structure.Retinal vessel is clearly middle-level at RFA, has more third dimension.In BEST sufferer eye, RFA clearly can demonstrate macula area and depart from scope, and does not show in FA.In addition due to the Absorption of retina trunk, RFA more can the border of clear display retina trunk.Because optical fundus hemoglobin, retina coloured groups, retinal pigment calmness and other retinal tissues all likely cause high quality graphic in RFA.
The present invention is also applicable to other mutually isostructural similar contrast apparatus, as Japanese Nidex (Maimonides gram) and TOPCON (opening up Pu Kang) etc. should be passable.
Say abbreviation: FA, fluorescein angiographic; RFA: without red smooth radiography; RF: noinvasive light; SD-OCT: coherence in frequency domain optical tomograph; Confocal scanning laser ophthalmoscope (CSLO).
Claims (3)
1. without a using method for red smooth contrast apparatus, it is characterized in that: the method is carried out in accordance with the following steps:
(1). first carry out conventional FA inspection to contrast apparatus, that is: excitation wavelength: 488nm, emission wavelength: 500nm, image resolution ratio 768*768 pixel, stain: fluorescein sodium, pick-up lens shooting angle 30 ° or 55 °, camera lens has optical filter;
(2), after .FA venous phase, be converted to by detecting pattern without red optical mode RF rapidly, now optical filter is removed, and equipment have recorded more reflected light;
(3). carry out under FA identical parameters without red smooth angiography, be RFA.
2. the using method without red smooth contrast apparatus according to claim 1, it is characterized in that: in step (2), after FA venous phase, be converted to by detecting pattern without red optical mode RF in 2 ~ 3 seconds, optical filter removes.
3. the using method without red smooth contrast apparatus according to claim 1, is characterized in that: described contrast apparatus is retinal vessel radiography and the OCT of the production of Heidelberg, Germany company.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510245848.5A CN104856651B (en) | 2015-05-13 | 2015-05-13 | A kind of application method without red smooth contrast apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510245848.5A CN104856651B (en) | 2015-05-13 | 2015-05-13 | A kind of application method without red smooth contrast apparatus |
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| CN104856651A true CN104856651A (en) | 2015-08-26 |
| CN104856651B CN104856651B (en) | 2018-10-16 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201431446Y (en) * | 2009-04-24 | 2010-03-31 | 陈平怀 | Fundus observation and recording device utilizing LED light source |
| CN201624637U (en) * | 2009-08-21 | 2010-11-10 | 上海市第一人民医院 | Tunable laser combination confocal laser synchronous fundus fluoresceince angiography system |
| CN102014732A (en) * | 2008-02-28 | 2011-04-13 | 卡尔蔡司医疗技术股份公司 | Ophthalmologic apparatus and method for the observation, examination, diagnosis, and/or treatment of an eye |
| CN103750814A (en) * | 2013-12-31 | 2014-04-30 | 苏州微清医疗器械有限公司 | Fundus scanning imaging device |
| US20140228681A1 (en) * | 2012-02-03 | 2014-08-14 | Oregon Health & Science University | In vivo optical flow imaging |
| CN104168818A (en) * | 2012-03-21 | 2014-11-26 | 欧视博公司 | Examination instrument |
-
2015
- 2015-05-13 CN CN201510245848.5A patent/CN104856651B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102014732A (en) * | 2008-02-28 | 2011-04-13 | 卡尔蔡司医疗技术股份公司 | Ophthalmologic apparatus and method for the observation, examination, diagnosis, and/or treatment of an eye |
| CN201431446Y (en) * | 2009-04-24 | 2010-03-31 | 陈平怀 | Fundus observation and recording device utilizing LED light source |
| CN201624637U (en) * | 2009-08-21 | 2010-11-10 | 上海市第一人民医院 | Tunable laser combination confocal laser synchronous fundus fluoresceince angiography system |
| US20140228681A1 (en) * | 2012-02-03 | 2014-08-14 | Oregon Health & Science University | In vivo optical flow imaging |
| CN104168818A (en) * | 2012-03-21 | 2014-11-26 | 欧视博公司 | Examination instrument |
| CN103750814A (en) * | 2013-12-31 | 2014-04-30 | 苏州微清医疗器械有限公司 | Fundus scanning imaging device |
Non-Patent Citations (1)
| Title |
|---|
| 杨金昭: "共焦激光眼底造影及其在眼科的应用", 《现代仪器》 * |
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