CN104856008A - Non-full-nutrition formula food for atrophic gastritis - Google Patents
Non-full-nutrition formula food for atrophic gastritis Download PDFInfo
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Abstract
Description
技术领域 technical field
本发明属于药食同源类配方与新资源食品技术领域,具体是将 “药食同源之中药”的传统中医精髓理论和新资源食品有机结合起来,添加以短肽、益生元、氨基酸、碳水化合物、有保健功能的油脂、复合维生素、复合矿物质为辅料制成的萎缩性胃炎的全营养配方食品、特定全营养配方食品或非特定全营养配方食品。 The invention belongs to the technical field of medicine and food homologous formula and new resource food, and specifically combines the traditional Chinese medicine essence theory of "medicine and food homologous Chinese medicine" with new resource food, and adds short peptides, prebiotics, amino acids, Carbohydrates, fats with health functions, multivitamins, and multiminerals are complete nutritional formula foods for atrophic gastritis, specific complete nutritional formula foods or non-specific complete nutritional formula foods.
背景技术 Background technique
萎缩性胃炎也称慢性萎缩性胃炎,以胃黏膜上皮和腺体萎缩,数目减少,胃黏膜变薄,黏膜基层增厚,或伴幽门腺化生和肠腺化生,或有不典型增生为特征的慢性消化系统疾病,常表现为上腹部隐痛、胀满、嗳气,食欲不振,或消瘦、贫血等,无特异性,是一种多致病因素性疾病及癌前病变,萎缩性胃炎的病因:1、幽门螺杆菌(Hp)感染,在60%~90%的慢性胃炎患者的胃黏膜中可培养出Hp,1986年世界胃肠病学会第八届会议上便提出了Hp感染是慢性胃炎的重要病因之一;2、饮食习惯,吸烟,饮酒,食物刺激,损坏胃黏膜的药物等;3、免疫因素,在萎缩性胃炎,特别是胃体胃炎患者的血液、胃液或在萎缩黏膜的浆细胞内,常可找到壁细胞抗体或内因子抗体,故认为自身免疫反应是萎缩性胃炎的有关病因;4、胆汁或十二指肠液反流;5、体质因素,临床统计结果显示本病的发生与年龄呈显著的正相关,年龄愈大,胃黏膜机能“抵抗力”也愈差,容易受外界不利因素的影响而造成损伤;6、遗传因素,在A型萎缩性胃炎发病中的地位已被证实,在恶性贫血家庭成员中PCA、IFA阳性率高,萎缩性胃炎常见;7、金属接触,铅作业工作者胃溃疡发病率高,胃黏膜活组织检查发现萎缩性胃炎发病率也增高,除铅外很多重金属如汞、铜及锌等对胃黏膜都有一定的损伤作用;8、放射,放射治疗溃疡病或其他肿瘤,可使胃黏膜损伤甚至萎缩;9、缺铁性贫血,很多事实说明缺铁性贫血与萎缩性胃炎关系密切;10、慢性浅表性胃炎的继续等;“药食同源”是中华原创医学之中对人类最有价值的贡献之一;中医历来强调“药疗不如食疗”,食疗成为现代人追求返璞归真、健康饮食的最佳选择;让人们在享受美食的过程中祛除病痛,避免了打针、吃药,甚至手术之苦; Atrophic gastritis, also known as chronic atrophic gastritis, is characterized by atrophy of gastric mucosal epithelium and glands, reduced number, thinning of gastric mucosa, thickening of the submucosal layer, or accompanied by pyloric gland metaplasia and intestinal gland metaplasia, or atypical hyperplasia. Characteristic chronic digestive system diseases, often manifested as dull pain in the upper abdomen, fullness, belching, loss of appetite, or weight loss, anemia, etc., non-specific, is a disease with multiple pathogenic factors and precancerous lesions Etiology: 1. Helicobacter pylori (Hp) infection. Hp can be cultured in the gastric mucosa of 60% to 90% of patients with chronic gastritis. In 1986, it was proposed that Hp infection is chronic One of the important causes of gastritis; 2. Eating habits, smoking, drinking, food stimulation, drugs that damage gastric mucosa, etc.; Parietal cell antibodies or intrinsic factor antibodies can often be found in the plasma cells of atrophic gastritis, so autoimmune reactions are considered to be the cause of atrophic gastritis; 4. Bile or duodenal fluid reflux; 5. Physical factors, clinical statistics show that this The occurrence of the disease is significantly positively correlated with age. The older the gastric mucosa is, the worse the "resistance" of gastric mucosal function is, and it is easy to be damaged by external unfavorable factors; 6. Genetic factors, in the onset of type A atrophic gastritis It has been confirmed that the positive rate of PCA and IFA is high in pernicious anemia family members, and atrophic gastritis is common; 7. Metal exposure, lead workers have a high incidence of gastric ulcer, and the incidence of atrophic gastritis found in gastric mucosal biopsy In addition to lead, many heavy metals such as mercury, copper and zinc have certain damage to the gastric mucosa; 8. Radiation, radiation therapy for ulcer disease or other tumors can damage or even shrink the gastric mucosa; 9. Iron deficiency Anemia, many facts show that iron deficiency anemia is closely related to atrophic gastritis; 10, the continuation of chronic superficial gastritis, etc.; It has always been emphasized that "medicine therapy is not as good as diet therapy", and diet therapy has become the best choice for modern people to pursue a return to nature and a healthy diet; it allows people to get rid of pain in the process of enjoying delicious food, and avoids the pain of injections, medicine, and even surgery;
对于特殊营养食品,在美国、欧盟等发达国家都有相应的规定和开发应用;而我国GB29922-2013《特殊医学用途配方食品通则》食品安全国家标准中全营养食品明确规定:2.1.1全营养配方食品:可作为单一营养来源满足目标人群营养需求的特殊医学用途配方食品;2.1.2特定全营养配方食品:可作为单一营养来源满足目标人群在特定疾病或医学状况下营养需求的特殊医学用途配方食品; For special nutritional food, there are corresponding regulations and development and application in the United States, the European Union and other developed countries; while my country's GB29922-2013 "General Rules for Formulated Foods for Special Medical Purposes" in the national food safety standard for complete nutritional food clearly stipulates: 2.1.1 Complete nutrition Formula food: Formula food for special medical purposes that can be used as a single source of nutrition to meet the nutritional needs of the target population; 2.1.2 Specific complete nutritional formula: food for special medical purposes that can be used as a single source of nutrition to meet the nutritional needs of the target population under specific diseases or medical conditions formula food;
目前市场上有利用以食源性短肽为主要原料,添加药食两用的香菇、陈皮、枸杞、山药、茯苓、黄精等的提取物、复合维生素和矿物质组成复合配方,还有利用新资源食品为主要原料的产品,但还没有发现结合萎缩性胃炎的患者的体质特征,依据传统中医的精髓理论,因人而异,黄金配伍以多种药食两用的中药提取物精华、短肽为主要原料,以益生元、碳水化合物、有保健功能的油脂、氨基酸、多种维生素、多种矿物质为辅料制成的全营养配方食品、特定全营养配方食品、非全营养配方食品或类似产品。 At present, there are compound formulas in the market that use food-derived short peptides as the main raw materials, add extracts of shiitake mushrooms, tangerine peel, wolfberry, yam, poria cocos, sealwort, etc., multivitamins and minerals for both medicinal and edible purposes. Resource food is the main raw material of the product, but the physical characteristics of patients combined with atrophic gastritis have not been found. According to the essence theory of traditional Chinese medicine, it varies from person to person. Peptide as the main raw material, complete nutritional formula food, specific complete nutritional formula food, non-complete nutritional formula food or similar product.
发明目的purpose of invention
本发明的目的是在继承中医精髓理论治病方法上,开创性将多种改善萎缩性胃炎患者的肠道微生态的新资源食品与“药食同源之中药”复方的提取物有机结合起来, 添加以短肽、氨基酸、碳水化合物、有保健功能的油脂、多种维生素、多种矿物质为辅料,不仅能够补充免疫力低下的萎缩性胃炎的患者所必需营养素,改善机体营养状况,还能并利用药食两用中草药中的功能因子调节机体功能,毒副作用小、安全有效,且人们容易接受的适合感染幽门螺杆菌的患者食用的全营养配方食品、特定全营养配方食品或非特定全营养配方食品。 The purpose of this invention is to creatively combine a variety of new resource foods that can improve the intestinal microecology of patients with atrophic gastritis with the extracts of the "medicine and food homologous traditional Chinese medicine" compound in the method of inheriting the essence of traditional Chinese medicine. , Adding short peptides, amino acids, carbohydrates, oils with health care functions, multivitamins, and multiminerals as auxiliary materials can not only supplement the essential nutrients for patients with atrophic gastritis with low immunity, improve the nutritional status of the body, but also It can also use the functional factors in the dual-purpose Chinese herbal medicine to regulate the function of the body, has little toxic and side effects, is safe and effective, and is easy to accept for patients infected with Helicobacter pylori. Complete nutritional formula food, specific complete nutritional formula food or non-specific nutritional formula food Complete nutritional formula food.
发明内容:Invention content:
本研发团队根据《特殊医学用途配方食品通则》的要求,结合萎缩性胃炎患者的体质特征,综合当今美国哈佛大学的先进生理学、医药、营养学及临床应用等研究成果,依据“消中寓补”、“均衡调养”的传统中医的精髓理论(肝、脾、肾三脏同调为主原则),采用一种或几种药食两用的中药提取物精华及新资源食品、短肽为主要原料,以益生元、碳水化合物、有保健功能的油脂、氨基酸、多种维生素及矿物质辅料,不仅可作为单一营养来源满足萎缩性胃炎的患者的营养需求,还有疏肝理气、和胃止痛、滋阴养胃、清热除湿、行气活血、破瘀散结、疏通经脉及增强免疫力的功效的全营养配方食品、特定全营养配方食品或非特定全营养配方食品(组合成的复合配方); In accordance with the requirements of the "General Rules for Formulated Foods for Special Medical Purposes", combined with the physical characteristics of patients with atrophic gastritis, and comprehensive research results in advanced physiology, medicine, nutrition and clinical application of Harvard University in the United States, the research and development team is based on the principle of "replenishing while eliminating ", "Balanced Nursing Care" is the essence theory of traditional Chinese medicine (the main principle is that the three internal organs of the liver, spleen, and kidney are harmonized), and one or several kinds of Chinese medicine extracts with both medicinal and edible uses, as well as new resource foods and short peptides are used as the main Raw materials, including prebiotics, carbohydrates, oils with health functions, amino acids, multi-vitamins and mineral accessories, can not only meet the nutritional needs of patients with atrophic gastritis as a single source of nutrition, but also soothe the liver, regulate qi, and relieve pain in the stomach , nourishing yin and stomach, clearing heat and dehumidification, promoting qi and blood circulation, removing stasis and stagnation, dredging meridians and enhancing immunity, full-nutrient formula food, specific full-nutrition formula food or non-specific full-nutrition formula food (combined compound formula );
1、本发明配方的主要成分为: 1, the main component of formula of the present invention is:
中药提取物是根据萎缩性胃炎患者的体质特征从中医理论中的肝、脾、肾三脏同调为主原则,利用药食两用中草药中的功能因子调节机体功能增强抵抗力,并选取以下几大类药物进行配伍;其中:冬虫夏草功效主要有调节免疫系统功能、抗肿瘤、抗疲劳、补肺益肾,止血化痰,秘精益气、美白祛黑等多种功效;灵芝孢子粉,铁皮石斛,益胃生津,滋阴清热;白术,除湿益燥,和中益气,温中,去脾胃中湿,除胃热,强脾胃,进饮食,安胎;黄芩,有清热燥湿,凉血安胎,解毒功效;黄芪,其有增强机体免疫功能、保肝、利尿、抗衰老、抗应激、降压和较广泛的抗菌作用;马尾连,清热燥湿,解毒;姜半夏,降逆止呕;党参补中益气、止渴、健脾益肺,养血生津;木香,行气,止痛,健脾,消食;香附,理气解郁;调经止痛;安胎;延胡索,用于行气止痛、活血散瘀、跌打损伤等;川朴,行气消积;燥湿除满;降逆平喘;肉桂,补元阳,暖脾胃,除积冷,通血脉;栀子,清热,泻火,凉血;白背三七,降血糖、清热凉血;活血止痛;止血;蛹虫草,中医认为,虫草入肺肾二经,既能补肺阴,又能补肾阳,主治肾虚,阳痿遗精,腰膝酸痛,病后虚弱,久咳虚弱,劳咳痰血,自汗盗汗等,是唯一的一种能同时平衡、调节阴阳的中药;苏子,降气消痰,止咳平喘,润肠通便;香橼,具有理气宽中,消胀降痰之功效;鸡内金,宽中健脾,消食磨胃;红曲米,活血消食,健脾暖胃,赤白痢下水谷;玫瑰花,柔肝醒胃,舒气活血,美容养颜,令人神爽,对幽门螺杆菌有很强的抑菌作用; According to the physical characteristics of patients with atrophic gastritis, the Chinese medicine extract is based on the principle of the coordination of the liver, spleen and kidney in the theory of traditional Chinese medicine, and uses the functional factors in the dual-purpose Chinese herbal medicine to adjust the body's function and enhance the resistance, and select the following Compatibility of large categories of drugs; Among them: the effects of Cordyceps sinensis mainly include regulating immune system function, anti-tumor, anti-fatigue, nourishing the lungs and kidneys, stopping bleeding and reducing phlegm, secreting lean energy, whitening and removing blackness, etc.; Ganoderma lucidum spore powder, Dendrobium officinale , nourishing the stomach and promoting body fluid, nourishing yin and clearing heat; Atractylodes macrocephala, dehumidifying and benefiting dryness, harmonizing qi, warming the middle, removing dampness in the spleen and stomach, removing stomach heat, strengthening the spleen and stomach, eating and drinking, and preventing miscarriage; Scutellaria baicalensis, clearing heat and dampness, cooling blood Anti-abortion, detoxification effect; Astragalus, which can enhance the immune function of the body, protect the liver, diuresis, anti-aging, anti-stress, lower blood pressure and a wider range of antibacterial effects; Maweilian, clear away heat and dampness, detoxify; Jiang Pinellia, reduce adverse effects Vomiting; Codonopsis tonifying the middle and replenishing Qi, quenching thirst, strengthening the spleen and lungs, nourishing blood and promoting body fluid; woody fragrance, promoting qi, relieving pain, invigorating the spleen, and eliminating food; Rhizoma Cyperi, regulating qi and relieving depression; regulating menstruation and relieving pain; anti-abortion; corydalis, used for Promoting qi and relieving pain, promoting blood circulation to dissipate blood stasis, bruises, etc.; Chuanpu, promoting qi and eliminating stagnation; Clearing heat, purging fire, cooling blood; white back notoginseng, lowering blood sugar, clearing heat and cooling blood; promoting blood circulation and relieving pain; hemostasis; Kidney deficiency, impotence and nocturnal emission, sore waist and knees, weakness after illness, chronic cough and weakness, coughing up sputum and blood, spontaneous sweating, etc. It is the only traditional Chinese medicine that can balance and regulate yin and yang at the same time; Asthma relief, laxative; citron, has the effect of regulating qi and widening the middle, reducing swelling and reducing phlegm; chicken inner gold, widening the middle and invigorating the spleen, eliminating food and grinding the stomach; red yeast rice, promoting blood circulation and eliminating food, strengthening the spleen and warming the stomach, red and white dysentery Xiashuigu; roses, soften the liver and wake up the stomach, relieve qi and activate blood, beautify the skin, make people feel refreshed, and have a strong antibacterial effect on Helicobacter pylori;
本发明所述的药食两用中药提取物是指冬虫夏草(冬虫夏草菌丝体)、灵芝孢子粉(破壁)、灵芝、铁皮石斛、白术、黄芩、黄芪、马尾连、姜半夏、党参、木香、香附、延胡索、炒川楝子、焦三仙、炒苍术、川朴、桂枝、炒白芍、柴胡、枳壳、元胡、吴茱萸、肉桂、厚朴、莪术、绿梅花、当归、沙参、麦门冬、丹参、太子参、栀子、白背三七、蛹虫草、苏子、香橼、鸡内金、红曲米、玫瑰花、麦芽、薏苡仁、砂仁、猴头菇、肉豆蔻、沙棘、木瓜、莱菔子、山楂、黄精、钝顶螺旋藻、荔枝核、紫苏、蒲公英、金银花、大枣、桔梗、佛手、松花粉、玉竹、乌梅、生姜、丁香、酵母、圆苞车前子壳、布渣叶、耳叶牛皮消、蛋白核小球藻、雪莲培养物、乳矿物盐其中的一种、几种或全部,采用生物酶解或预水解SBE提取并微胶囊化,经喷雾干燥及冷冻干燥的提取物后的混合物; The medicinal and edible Chinese medicine extract of the present invention refers to Cordyceps sinensis (Cordyceps sinensis mycelium), Ganoderma lucidum spore powder (broken wall), Ganoderma lucidum, Dendrobium officinale, Atractylodes macrocephala, Scutellaria baicalensis, Astragalus root, Ponytail, Ginger Pinellia, Codonopsis, Woody , Cyperus, Corydalis, Stir-fried Toosendan, Jiao Sanxian, Stir-fried Atractylodes, Chuanpu, Guizhi, Stir-fried Paeoniae Alba, Bupleurum, Citrus aurantium, Yuanhu, Evodia, Cinnamon, Magnolia officinalis, Curcuma, Green Plum, Angelica, Sand Ginseng, Ophiopogon japonicus, Salvia miltiorrhiza, Radix Pseudostellariae, Gardenia, Panax notoginseng, Cordyceps militaris, perilla, citron, gallinaceae, red yeast rice, rose, malt, coix seed, amomum, Hericium erinaceus , nutmeg, sea buckthorn, papaya, radish, hawthorn, sealwort, spirulina platensis, lychee core, perilla, dandelion, honeysuckle, jujube, bellflower, bergamot, pine pollen, polygonatum, ebony, ginger, clove, yeast One, several or all of them, psyllium husk, cloth slag leaves, auricularia psoriasis, chlorella pyrenoidosa, snow lotus culture, and milk mineral salts are extracted by biological enzymatic or prehydrolyzed SBE and Microencapsulated, spray-dried and freeze-dried extract mixtures;
2、短肽:即为低聚肽,是指利用生物酶工程技术从动物或植物蛋白中分离提取的一类小分子蛋白质,其平均分子量在1000Dalton以下,易溶于水,对酸、热稳定,可以不需经过消化而直接吸收,生物利用率高,在吸收和利用上优于游离的氨基酸和完整的蛋白质,可应用于蛋白质补充食品中,尤其对于消化吸收能力低下的人群,短肽是极佳的氮源,除营养功能外,短肽还具有一系列的生理活性功能:提高小肠的消化吸收功能, 增强机体免疫力,抗氧化, 辅助调节血糖,辅助调节血脂,辅助降血压,抗辐射, 促进矿物质吸收, 增强药食两用中草药中功能因子的作用效果; 2. Short peptides: oligopeptides, which refer to a class of small molecular proteins isolated and extracted from animal or vegetable proteins by bio-enzyme engineering technology. The average molecular weight is below 1000Dalton, easily soluble in water, stable to acid and heat , can be directly absorbed without digestion, has high bioavailability, and is superior to free amino acids and complete proteins in absorption and utilization. It can be used in protein supplement foods, especially for people with low digestion and absorption capabilities. Short peptides are Excellent nitrogen source. In addition to nutritional functions, short peptides also have a series of physiologically active functions: improving digestion and absorption of the small intestine, enhancing immunity, anti-oxidation, assisting in regulating blood sugar, assisting in regulating blood lipids, assisting in lowering blood pressure, and anti-aging. Radiation, to promote mineral absorption, to enhance the effect of functional factors in Chinese herbal medicines;
本发明所述的短肽是指玉米低聚肽、小麦低聚肽、海洋胶原肽、海洋骨原肽、大豆蛋白肽、乳清蛋白肽、卵白蛋白肽其中一种、几种或全部混合; The short peptide in the present invention refers to one, several or all of corn oligopeptides, wheat oligopeptides, marine collagen peptides, marine bone peptides, soybean protein peptides, whey protein peptides, and ovalbumin peptides;
3、益生元: 以促益生菌肠道定植、肠道收敛、降低肠道pH环境,也不被大多数的肠道腐败菌利用,但可以促进人体内有益细菌——乳杆菌、双歧 杆菌的生长繁殖,从而可以抑制腐败菌生长,有助于改善和维持肠道正常功能;长期食用可以延缓衰老、通便、提高免疫力、减轻肝脏负担、提高营养素的吸收率,特别是能够改善机体对钙、铁、锌等金属离子 的吸收;可选择性地促进有益菌(双歧、乳酸)的生长繁殖外,还可代谢为酸性产物如乳酸等有机酸,使结肠内pH值降低,抑制肠道有害细菌的生长;使小肠内水电解质滞留在肠腔,产生高渗效果,刺激肠蠕动引起缓泻,从而促进肠道内毒素及其他毒性物质的排出,乳果糖还可直接灭活肠道中内毒素、降低肠道pH值,已广范应用于增强萎缩性胃炎的抵抗力的治疗; 3. Prebiotics: to promote intestinal colonization of probiotics, intestinal convergence, reduce intestinal pH environment, and not be used by most intestinal spoilage bacteria, but can promote beneficial bacteria in the human body - Lactobacillus, Bifidobacteria growth and reproduction, which can inhibit the growth of spoilage bacteria, and help to improve and maintain the normal function of the intestinal tract; long-term consumption can delay aging, laxative, improve immunity, reduce the burden on the liver, improve the absorption rate of nutrients, especially to improve the body Absorption of calcium, iron, zinc and other metal ions; it can selectively promote the growth and reproduction of beneficial bacteria (bifido, lactic acid), and can also be metabolized into acidic products such as lactic acid and other organic acids, reducing the pH value in the colon and inhibiting The growth of harmful bacteria in the intestinal tract; make the water and electrolyte in the small intestine stay in the intestinal cavity, produce a hypertonic effect, stimulate intestinal peristalsis and cause laxative, thereby promoting the discharge of intestinal toxins and other toxic substances, lactulose can also directly inactivate intestinal Toxins, lower intestinal pH, have been widely used in the treatment of enhancing the resistance of atrophic gastritis;
本发明所述的益生元为:山药、茯苓、薏仁、鸡内金、芡实、菊粉的提取物、棉子低聚糖、水苏糖、酵母、低聚异麦芽糖、海藻糖、低聚果糖、大豆低聚糖、低聚木糖其中的一种、几种或全部混合; The prebiotics described in the present invention are: Chinese yam, poria cocos, coix seed, gallinacea, Gorgon fruit, extract of inulin, cottonseed oligosaccharide, stachyose, yeast, isomaltooligosaccharide, trehalose, fructooligosaccharide , soybean oligosaccharides, xylooligosaccharides, one, several or all mixed;
4、碳水化合物:碳水化合物是由碳、氢和氧三种元素组成,它是为人体提供热能的三种主要的营养素中最廉价的营养素,摄入充足时,在体内可迅速氧化及时提供能量,避免将宝贵的蛋白质用来提供能量,碳水化合物也是细胞膜的糖蛋白、神经组织的糖脂以及传递遗传信息的脱氧核糖核酸(DNA)的重要组成成分,而且碳水化合物中含有的糖原,当其在肝内储备充足时,肝细胞对某些有毒的化学物质和各种致病微生物产生的毒素有较强的解毒能力; 4. Carbohydrates: Carbohydrates are composed of three elements: carbon, hydrogen and oxygen. It is the cheapest nutrient among the three main nutrients that provide heat energy for the human body. When ingested sufficiently, it can be rapidly oxidized in the body to provide energy in a timely manner , avoid using precious protein to provide energy, carbohydrates are also important components of glycoproteins in cell membranes, glycolipids in nerve tissues, and deoxyribonucleic acid (DNA) that transmit genetic information, and glycogen contained in carbohydrates, when When its reserves in the liver are sufficient, the liver cells have a strong ability to detoxify certain toxic chemicals and toxins produced by various pathogenic microorganisms;
本发明所述的碳水化合物是指L-阿拉伯糖、果糖、蚌肉多糖、抗性糊精、壳寡糖、酵母β-葡聚糖、多聚果糖、半乳糖、乳糖、葡萄糖、麦芽糖、碳水化合物、有保健功能的油脂、、淀粉、糖元其中的一种、几种或全部混合; The carbohydrates described in the present invention refer to L-arabinose, fructose, mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast β-glucan, polyfructose, galactose, lactose, glucose, maltose, carbohydrate One, several or all of compounds, fats with health functions, starch, and glycogen are mixed;
5.有保健功能的油酯是指对人身体有保健作用,并能增加终产品能量,使本发明的终产品每100g所含有的能量应不低于295kJ(70kcal);如鱼油是人体血管的清道夫,还能预防动脉硬化、中风和心脏病。鱼油是高血压、冠心病、脑中风、糖尿病、风湿性关节炎、癌症等疾病;亚麻籽油有减肥、降低胆固醇、改善肾功能等作用;牡丹籽油有降血脂和降血压,增强自身免疫,预防糖尿病,防治癌症的功效;翅果油有防止和治疗高血压,高血脂,血管硬化等病症的功效; 5. The oil and ester with health care function means that it has a health care effect on the human body and can increase the energy of the final product, so that the energy contained in every 100g of the final product of the present invention should not be less than 295kJ (70kcal); It can also prevent arteriosclerosis, stroke and heart disease. Fish oil is effective for hypertension, coronary heart disease, stroke, diabetes, rheumatoid arthritis, cancer and other diseases; linseed oil has the effects of losing weight, lowering cholesterol, and improving kidney function; peony seed oil can lower blood fat and blood pressure, and enhance autoimmunity , prevent diabetes and prevent cancer; samara oil has the effect of preventing and treating hypertension, hyperlipidemia, vascular sclerosis and other diseases;
本发明所述的有保健功能的油脂是指亚麻籽油、牡丹籽油、翅果油、水飞蓟籽油、植物甾醇酯、御米油、茶叶籽油、鱼油、鱼油提取物、花生四烯酸油脂、蔗糖聚酯、DHA藻油、磷虾油、盐地碱蓬籽油、美藤果油、盐肤木果油、中链甘油三酯、黄明胶、光皮梾木果油、长柄扁桃油、中长链脂肪酸食用油、元宝枫籽油、表没食子儿茶素没食子酸酯、甘油二酯油、叶黄素酯其中的一种、几种或全部混合; The fats and oils with health care function described in the present invention refer to linseed oil, peony seed oil, samara oil, milk thistle seed oil, phytosterol ester, royal rice oil, tea seed oil, fish oil, fish oil extract, peanut four Alkenic acid oil, sucrose polyester, DHA algae oil, krill oil, Suaeda salsa seed oil, saponica fruit oil, salina fruit oil, medium-chain triglycerides, yellow gelatin, eucalyptus fruit oil, Long handle almond oil, medium and long chain fatty acid edible oil, ingot maple seed oil, epigallocatechin gallate, diglyceride oil, lutein ester, one, several or all mixed;
6.氨基酸:分为必需氨基酸与非必需氨基酸,是构成蛋白质的基本单位,赋予蛋白质特定的分子结构形态,使其具有生化活性;摄取适量的蛋氨酸有助于人体内各种含硫化合物的代谢并且其所含的甲基对有毒物或药物进行甲基化而起到解毒的作用;亮氨酸能够修复肌肉,控制血糖,并给身体组织提供能量,必需氨基酸苯丙氨酸可以抑制癌瘤生长,又可以降低药物的毒副作用,赖氨酸可提高食物蛋白质的吸收和利用,达到均衡营养,促进生长发育;精氨酸有助于将血液中的氨转变为尿素而排泄出去;对于高氨血症,肝脏机能障碍等均有功效;组氨酸降低胃液酸度,缓和胃肠手术的疼痛,减轻妊娠期呕吐及胃部灼热感,抑制由植物神经紧张而引起的消化道溃烂,对过敏性疾病,如哮喘等也有功效;色氨酸可以预防糙皮病、抑郁症,改善睡眠和调节情绪; 6. Amino acid: divided into essential amino acid and non-essential amino acid, which is the basic unit of protein, endows protein with specific molecular structure and form, and makes it biochemically active; intake of appropriate amount of methionine is helpful for the metabolism of various sulfur-containing compounds in the human body And the methyl group contained in it can detoxify toxic substances or drugs through methylation; leucine can repair muscles, control blood sugar, and provide energy to body tissues; the essential amino acid phenylalanine can inhibit cancer growth, and can reduce the toxic and side effects of drugs, lysine can improve the absorption and utilization of food protein, achieve balanced nutrition, and promote growth and development; arginine helps to convert ammonia in the blood into urea and excrete it; for high Ammoniaemia, liver dysfunction, etc. are effective; histidine reduces the acidity of gastric juice, relieves the pain of gastrointestinal surgery, relieves vomiting during pregnancy and stomach burning sensation, inhibits digestive tract ulcers caused by autonomic nervous tension, and is effective for allergies Diseases, such as asthma, are also effective; tryptophan can prevent pellagra, depression, improve sleep and regulate mood;
本发明所述的氨基酸是指L-谷氨酰胺、γ-氨基丁酸、珠肽粉、蛋氨酸、异亮氨酸、酪氨酸、苯丙氨酸、赖氨酸、精氨酸、组氨酸、色氨酸、瓜氨酸、鸟氨酸、牛磺酸其中的一种、几种或全部混合; Amino acid in the present invention refers to L-glutamine, γ-aminobutyric acid, pearl peptide powder, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histamine Acid, tryptophan, citrulline, ornithine, taurine, one, several or all mixed;
7.维生素和矿物质:维生素和矿物质是人体必需的营养素,本发明中添加的维生素为维生素和矿物质是人体必需的营养素; 7. Vitamins and minerals: vitamins and minerals are essential nutrients for the human body, and the vitamins added in the present invention are vitamins and minerals are essential nutrients for the human body;
本发明中添加的维生素为维生素A、维生素D、维生素E、维生素K、维生素K1、维生素C、维生素B1、维生素B2、维生素B6、维生素B12、维生素Be、维生素Bu、烟酸、叶酸、泛酸、胆碱、生物素其中的 一种、几种或全部混合; The vitamins added in the present invention are vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin Be, vitamin Bu, niacin, folic acid, pantothenic acid, One, several or all of choline and biotin are mixed;
本发明中添加的矿物质为钙、磷、钾、钠、镁、氯、铁、锌、硒、铜、锰、碘、氟、铬、钼其中的一种、几种或全部混合,本发明所述的矿物质添加为该矿物质的有机或无机化合物; The minerals added in the present invention are calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, one, several or all of them mixed. The mineral is added as an organic or inorganic compound of the mineral;
本发明中维生素矿物质的添加量参照《特殊医学用途配方食品通则》执行,现以1000g成品为例,添加量为维生素A0.01g、维生素D0.000015g、维生素E0.12g、维生素K0.0075g、维生素K10.00001g、维生素C10.625g、维生素B10.016g、维生素B20.016g、维生素B60.015g、维生素B0.0023g、维生素Be 、维生素Bu、烟酸0.2g、叶酸0.003g、泛酸0.051g、胆碱2.5g、生物素0.000057g、钙6.2g、磷4.5g、钾10g、钠16.17g、镁1.7g、氯、铁0.15g、锌6.2g、硒0.00012g、铜0.007g、锰0.018g、碘0.00001g、氟0.00001g、铬0.00001g、钼0.00001g; The amount of added vitamins and minerals in the present invention is implemented with reference to the "General Rules for Formulated Foods for Special Medical Purposes". Now taking 1000g of finished products as an example, the added amounts are 0.01g of vitamin A, 0.000015g of vitamin D, 0.12g of vitamin E, 0.0075g of vitamin K, Vitamin K10.00001g, vitamin C10.625g, vitamin B10.016g, vitamin B20.016g, vitamin B60.015g, vitamin B0.0023g, vitamin Be, vitamin Bu, niacin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, bile Alkali 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, Iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g;
8.采用上述集成创新工艺将各种配料混合均匀制成粉状的固体饮料、颗粒剂,并分装成10g/包,用约150ml开水溶解后,直接饮用或经鼻饲摄入;也可以加入适量附料制成胶囊、片剂或加入甜味剂和黑芝麻粉制成饼干等快速、方便食品便于外出携带食用,若做成饮料则省去经喷雾干燥,少添加辅料等,分装成10-65ml/瓶,每日早、中、晚饭后0.5小时各饮1瓶,所有操作均在符合《特殊医学用途配方食品良好生产规范》要求的洁净干燥环境内进行; 8. Use the above-mentioned integrated innovative process to mix various ingredients evenly to make powdered solid beverages and granules, and pack them into 10g/bags, dissolve them in about 150ml of boiling water, drink them directly or take them through nasal feeding; you can also add Appropriate amount of additives are made into capsules, tablets, or sweeteners and black sesame powder are added to make quick and convenient foods such as biscuits, which are convenient to carry and eat when going out. 10-65ml/bottle, drink one bottle every morning, noon, and 0.5 hours after dinner, all operations are carried out in a clean and dry environment that meets the requirements of "Good Manufacturing Practice for Formula Foods for Special Medical Purposes";
本非全营养配方食品的特性及其对机体的作用主要表现在以下几个方面: The characteristics of this non-complete nutritional formula food and its effects on the body are mainly manifested in the following aspects:
1.本发明是根据《特殊医学用途配方食品通则》的要求,结合萎缩性胃炎的患者的体质特征,综合当今美国哈佛大学的先进生理学、医药、营养学及临床应用等研究成果研制的,因人而异,黄金配伍; 1. The present invention is developed according to the requirements of "General Rules for Formulated Foods for Special Medical Purposes", combined with the physical characteristics of patients with atrophic gastritis, and the research results of advanced physiology, medicine, nutrition and clinical application of Harvard University in the United States. Different people, golden combination;
2.本发明依据“消中寓补”、“均衡调养”的传统中医的精髓理论(肝、脾、肾三脏同调为主原则),采用多种药食两用的中药提取物精华、短肽为主要原料,以益生元、碳水化合物、有保健功能的油脂、氨基酸、多种维生素及矿物质为辅料,各种配料的有机组合,将各种功能进行融合,并通过有效成分之间的协同作用,增强作用效果; 2. The present invention is based on the quintessence theory of traditional Chinese medicine (liver, spleen, and kidney are the main principle of the same coordination of the liver, spleen, and kidney) based on the essence theory of "dispelling the middle and nourishing" and "balanced recuperation", and adopts a variety of medicinal and edible Chinese medicine extract essences, short-term Peptide is the main raw material, with prebiotics, carbohydrates, oils with health care functions, amino acids, multi-vitamins and minerals as auxiliary materials, the organic combination of various ingredients, the integration of various functions, and the combination of active ingredients Synergistic effect, enhance the effect;
3. 具有高效吸收性,利用本发明配方,各种组分采用适宜的比例搭配制备的食品,经一定量水溶解后呈等渗状态,能快速通过胃到达小肠,吸收快速、完全,可以迅速补充萎缩性胃炎患者所需营养; 3. It has high absorbability. Using the formula of the present invention, the food prepared with appropriate ratios of various components will be in an isotonic state after being dissolved in a certain amount of water, and can quickly pass through the stomach to the small intestine, absorbing quickly and completely, and can quickly Supplement the nutrition needed by patients with atrophic gastritis;
4.本发明配方中采用各种药食两用中草药的提取物,含有多种功能活性成分,不仅提高了功能因子的浓度,减少各种杂质的摄入,有助于减轻肝肾负担,具有增强人体抵抗力的作用,还有疏肝理气、和胃止痛、滋阴养胃、清热除湿、行气活血、破瘀散结、疏通经脉及增强免疫力的功效; 4. The formula of the present invention adopts the extracts of various medicinal and edible Chinese herbal medicines, and contains a variety of functional active ingredients, which not only increases the concentration of functional factors, reduces the intake of various impurities, helps to reduce the burden on the liver and kidney, and has the function of strengthening the human body. The role of immunity also has the effects of soothing the liver and regulating qi, harmonizing the stomach and relieving pain, nourishing yin and nourishing the stomach, clearing heat and dehumidification, promoting qi and blood circulation, breaking stasis and dispelling stagnation, dredging meridians and enhancing immunity;
5.本发明配方食品以多种来源的食源性生物活性短肽为氮源,因为短肽不需消化即可吸收,更有利于机体的利用,可以有效改善萎缩性胃炎患者负氮平衡,而且食源性短肽能够改善肠粘膜上皮细胞的结构和功能,提高肠粘膜的吸收能力; 5. The formula food of the present invention uses food-derived bioactive short peptides from various sources as the nitrogen source, because short peptides can be absorbed without digestion, which is more conducive to the utilization of the body, and can effectively improve the negative nitrogen balance of patients with atrophic gastritis. Moreover, food-derived short peptides can improve the structure and function of intestinal mucosal epithelial cells, and improve the absorption capacity of intestinal mucosa;
6.本发明配方中所含的益生元,通过促进肠内益生菌的生长繁殖,抑制腐败菌的生长,同时在肠粘膜表面形成一道保护屏障,可以抵御肠道腐败菌对肠粘膜的损伤,减少肠内有害物质的吸收,还可以促进肠道蠕动,加速肠内残留物质的排出,可以防止便秘,而且通过促进肠道益生菌的生长繁殖也可以增强机体免疫力,短肽、碳水化合物与活性多糖等生物活性物质具有协同作用; 6. The prebiotics contained in the formula of the present invention can inhibit the growth of spoilage bacteria by promoting the growth and reproduction of probiotics in the intestine, and at the same time form a protective barrier on the surface of the intestinal mucosa, which can resist the damage of intestinal spoilage bacteria to the intestinal mucosa. Reducing the absorption of harmful substances in the intestines can also promote intestinal peristalsis, accelerate the discharge of residual substances in the intestines, prevent constipation, and enhance the body's immunity by promoting the growth and reproduction of intestinal probiotics. Short peptides, carbohydrates and Biologically active substances such as active polysaccharides have synergistic effects;
7.本发明配方中所含的碳水化合物是为人体提供热能的三种主要的营养素,在体内可迅速氧化及时提供能量,避免将宝贵的蛋白质用来提供能量,碳水化合物也是细胞膜的糖蛋白、神经组织的糖脂以及传递遗传信息的脱氧核糖核酸(DNA)的重要组成成分,而且碳水化合物中含有的糖原,当其在肝内储备充足时,肝细胞对某些有毒的化学物质和各种致病微生物产生的毒素有较强的解毒能力; 7. The carbohydrates contained in the formula of the present invention are three main nutrients that provide heat energy for the human body. They can be oxidized rapidly in the body to provide energy in time, and avoid using valuable protein to provide energy. Carbohydrates are also glycoproteins of cell membranes, Glycolipids in nervous tissue and important components of deoxyribonucleic acid (DNA) that transmit genetic information, and glycogen contained in carbohydrates, when it is fully stored in the liver, liver cells are resistant to certain toxic chemicals and various The toxin produced by a pathogenic microorganism has a strong detoxification ability;
8.本发明配方中所含的有保健功能的油脂不仅对人身体有保健作用,并为人体提供正常生活所需的能量,使本发明的终产品每100g所含有的能量应不低于295kJ(70kcal); 8. The oil with health-care function contained in the formula of the present invention not only has a health-care effect on the human body, but also provides the human body with the energy required for normal life, so that the energy contained in every 100g of the final product of the present invention should not be less than 295kJ (70kcal);
9.本发明配方中所含的氨基酸,是构成蛋白质的基本单位,赋予蛋白质特定的分子结构形态,使其具有生化活性,有助于人体内各种含硫化合物的代谢并且其所含的甲基对有毒物或药物进行甲基化而起到解毒的作用,能够修复肌肉,控制血糖,并给身体组织提供能量,还可提高食物蛋白质的吸收和利用,达到均衡营养,促进生长发育; 9. The amino acid contained in the formula of the present invention is the basic unit of protein, endows protein with specific molecular structure, makes it have biochemical activity, helps the metabolism of various sulfur-containing compounds in the human body and the formazan contained in it The base can detoxify toxic substances or drugs by methylating them. It can repair muscles, control blood sugar, and provide energy to body tissues. It can also improve the absorption and utilization of food protein, achieve balanced nutrition, and promote growth and development;
10.本发明配方食品含多种维生素和矿物质,可迅速补充萎缩性胃炎患者所需的微量营养素,短肽通过与钙、铁、锌等的螯合后,更增加了矿物质元素的吸收率; 10. The formula food of the present invention contains a variety of vitamins and minerals, which can quickly supplement the micronutrients needed by patients with atrophic gastritis. After the short peptide is chelated with calcium, iron, zinc, etc., the absorption of mineral elements is increased Rate;
11.本发明配方中不含脂肪和胆固醇,能够在补充蛋白质、微量营养素的同时,不会增加脂肪、胆固醇的摄入,避免了肉、蛋等髙蛋白食物的不利影响。 11. The formula of the present invention does not contain fat and cholesterol, and can not increase the intake of fat and cholesterol while supplementing protein and micronutrients, and avoids the adverse effects of high-protein foods such as meat and eggs.
具体实施方式 Detailed ways
下面通过以下实施案例对本发明作进一步说明,它将有助于理解本发明。 The present invention will be further described below through the following examples, which will help to understand the present invention.
实施案例一 Implementation Case 1
实现本发明目的萎缩性胃炎非全营养配方食品是以结合萎缩性胃炎患者的体质特征,依据传统中医的精髓理论,因人而异,黄金配伍以一种、几种或全部的药食两用中药提取物精华及新资源食品、益生元为主要原料,以一种、几种或全部的短肽、碳水化合物、氨基酸、有保健功能的油脂、多种维生素、多种矿物质为辅料制成的全营养配方,或制成特定全营养配方食品和非全营养配方食品; To realize the purpose of the present invention, atrophic gastritis non-complete nutritional formula food is based on the physical characteristics of patients with atrophic gastritis, according to the essence theory of traditional Chinese medicine, and varies from person to person, and the golden compatibility is one, several or all of the medicine and food dual-purpose The essence of traditional Chinese medicine extracts, new resource foods, and prebiotics are the main raw materials, and one, several or all short peptides, carbohydrates, amino acids, oils with health functions, multivitamins, and multiminerals are used as auxiliary materials. full nutritional formula, or made into specific full nutritional formula food and non-full nutritional formula food;
按下列原料及其用量进行配方,药食两用的提取物及新资源食品: 冬虫夏草(冬虫夏草菌丝体)12g、灵芝孢子粉(破壁)11g、灵芝10g、铁皮石斛10g、白术9g、黄芩9g、黄芪8g、马尾连8g、姜半夏8g、党参7g、木香7g、香附7g、延胡索7g、炒川楝子7g、焦三仙6g、炒苍术6g、川朴6g、桂枝6g、炒白芍6g、柴胡6g、枳壳6g、当归6g、元胡5g、吴茱萸5g、肉桂5g、厚朴5g、莪术5g、绿梅花5g、沙参5g、麦门冬5g、丹参5g、太子参5g、栀子5g、白背三七5g、蛹虫草5g、苏子4g、香橼4g、鸡内金4g、红曲米4g、玫瑰花4g、麦芽4g、薏苡仁4g、砂仁4g、猴头菇4g、肉豆蔻4g、沙棘4g、木瓜4g、莱菔子4g、山楂3g、黄精3g、钝顶螺旋藻3g、荔枝核3g、紫苏3g、蒲公英3g、金银花2g、大枣2g、桔梗2g、佛手2g、松花粉2g、玉竹2g、乌梅2g、生姜2g、丁香2g、酵母2g、圆苞车前子壳1g、布渣叶1g、耳叶牛皮消1g、蛋白核小球藻1g、雪莲培养物1g、乳矿物盐1g、短肽200g、益生元100g、多种氨基酸100g、碳水化合物100g、有保健功能的油酯100g、维生素A0.01g、维生素D0.000015g、维生素E0.12g、维生素K0.0075g、维生素K10.00001g、维生素C10.625g、维生素B10.016g、维生素B20.016g、维生素B60.015g、维生素B0.0023g、维生素Be、维生素Bu、烟酸0.2g、叶酸0.003g、泛酸0.051g、胆碱2.5g、生物素0.000057g、钙6.2g、磷4.5g、钾10g、钠16.17g、镁1.7g、氯、铁0.15g、锌6.2g、硒0.00012g、铜0.007g、锰0.018g、碘0.00001g、氟0.00001g、铬0.00001g、钼0.00001g; Formulated according to the following raw materials and their dosage, medicinal and edible extracts and new resource foods: Cordyceps sinensis (Cordyceps sinensis mycelium) 12g, Ganoderma lucidum spore powder (broken wall) 11g, Ganoderma lucidum 10g, Dendrobium officinale 10g, Atractylodes macrocephala 9g, Scutellaria baicalensis 9g, Astragalus 8g, Ponytail 8g, Ginger pinellia 8g, Codonopsis 7g, Woody 7g, Rhizoma Cyperi 7g, Corydalis 7g, Stir-fried Toosendan 7g, Jiao Sanxian 6g, Stir-fried Atractylodes 6g, Chuanpu 6g, Guizhi 6g, Stir-fried white peony 6g, Bupleurum 6g, Citrus aurantium 6g, Angelica 6g, Yuanhu 5g, Evodia 5g, Cinnamon 5g, Magnolia officinalis 5g, Curcuma 5g, Lvmeihua 5g, Radix Ginseng 5g, Ophiopogon japonicus 5g, Salvia miltiorrhiza 5g, Pseudostellaria 5g, 5g Gardenia, 5g Panax notoginseng, 5g Cordyceps militaris, 4g perilla, 4g citron, 4g gallinaceous gold, 4g red yeast rice, 4g rose, 4g malt, 4g coix seed, 4g amomum, Hericium erinaceus 4g, nutmeg 4g, seabuckthorn 4g, papaya 4g, radish seed 4g, hawthorn 3g, Polygonatum 3g, spirulina platensis 3g, litchi core 3g, perilla 3g, dandelion 3g, honeysuckle 2g, jujube 2g, bellflower 2g, bergamot 2g, pine pollen 2g, Polygonatum 2g, ebony plum 2g, ginger 2g, clove 2g, yeast 2g, psyllium husk 1g , cloth dregs leaf 1g , auricularia auricularia 1g , chlorella pyrenoidosa 1g , snow lotus culture 1g of food, 1g of milk mineral salt , 200g of short peptide, 100g of prebiotic, 100g of various amino acids, 100g of carbohydrate, 100g of oil and ester with health care function, 0.01g of vitamin A, 0.000015g of vitamin D, 0.12g of vitamin E, vitamin K0 .0075g, Vitamin K10.00001g, Vitamin C10.625g, Vitamin B10.016g, Vitamin B20.016g, Vitamin B60.015g, Vitamin B0.0023g, Vitamin Be, Vitamin Bu, Niacin 0.2g, Folic Acid 0.003g, Pantothenic Acid 0.051 g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g;
制作时先将以是灵芝、铁皮石斛、白术、黄芩、黄芪、马尾连、姜半夏、党参、木香、香附、延胡索、炒川楝子、焦三仙、炒苍术、川朴、桂枝、炒白芍、柴胡、枳壳、元胡、吴茱萸、肉桂、厚朴、莪术、绿梅花、当归、沙参、麦门冬、丹参、太子参、栀子、白背三七、苏子、香橼、鸡内金、红曲米、玫瑰花、麦芽、薏苡仁、砂仁、猴头菇、肉豆蔻、沙棘、木瓜、莱菔子、山楂、黄精、钝顶螺旋藻、荔枝核、紫苏、蒲公英、金银花、大枣、桔梗、佛手、松花粉、玉竹、乌梅、生姜、丁香、酵母、圆苞车前子壳、布渣叶、耳叶牛皮消浸泡后加入β-环状糊精,用预水解SBE技术提取后,经喷雾干燥而制备的粉状物质,再添加生物酶解提取的冬虫夏草(冬虫夏草菌丝体)、灵芝孢子粉(破壁)、蛹虫草、蛋白核小球藻、雪莲培养物、乳矿物盐、短肽、益生元、氨基酸、碳水化合物、有保健功能的油脂、多种维生素及矿物质一起粉碎混合后进行120摄氏度高温灭菌1小时,然后混合均匀制成粉状的固体饮料、颗粒剂,并分装成10g/包,用约150ml开水溶解后,直接饮用或经鼻饲摄入;也可以加入适量附料制成胶囊、片剂或加入甜味剂和黑芝麻粉制成饼干等快速、方便食品便于外出携带食用,若做成饮料则省去经喷雾干燥,少添加辅料等,分装成10-65ml/瓶,每日早、中、晚饭后0.5小时各饮1瓶,所有操作均在符合《特殊医学用途配方食品良好生产规范》要求的洁净干燥环境内进行。 When making it, first use Ganoderma lucidum, Dendrobium officinale, Atractylodes macrocephala, Scutellaria baicalensis, Astragalus root, Horsetail, Ginger pinellia, Codonopsis pilosula, Woody incense, Rhizoma Cyperi, Corydalis, Stir-fried Toosendan, Jiao Sanxian, Stir-fried Atractylodes, Chuanpu, Guizhi, Stir-fried white Peony, Bupleurum, Citrus aurantium, Yuanhu, Evodia, Cinnamon, Magnolia officinalis, Curcuma, Green Plum Blossom, Angelica, Radix Ginseng, Ophiopogon japonicus, Salvia, Radix Pseudostellaria, Gardenia, Panax notoginseng, Perilla, Citron , gallinacea, red yeast rice, rose, malt, coix seed, amomum, Hericium erinaceus, nutmeg, sea buckthorn, papaya, radish seed, hawthorn, sealwort, spirulina platensis, lychee kernel, perilla, dandelion , honeysuckle, jujube, bellflower, bergamot, pine pollen, Polygonatum odoratum, dark plum, ginger, clove, yeast, round bract plantago husk, cloth dregs leaf, ear leaf cowhide , add β-cyclodextrin after soaking, and use After the pre-hydrolysis SBE technology extraction, the powdery substance prepared by spray drying, then add the Cordyceps sinensis (Cordyceps sinensis mycelium), Ganoderma lucidum spore powder (broken wall), Cordyceps militaris, Chlorella pyrenoidosa, Saussurea sinensis extracted by biological enzymolysis Culture, milk mineral salts, short peptides, prebiotics, amino acids, carbohydrates, fats with health functions, multivitamins and minerals are pulverized and mixed together, then sterilized at 120 degrees Celsius for 1 hour, and then mixed evenly to make a powder The solid beverages and granules are divided into 10g/packages, dissolved in about 150ml of boiling water, and then drunk directly or ingested through nasal feeding; it can also be made into capsules, tablets, or sweeteners and black sesame seeds by adding appropriate amount of additives Powder is made into biscuits and other quick and convenient food, which is convenient to carry and eat when going out. If it is made into beverage, spray drying is omitted, and auxiliary materials are added less. Drink 1 bottle, and all operations are carried out in a clean and dry environment that meets the requirements of "Good Manufacturing Practice for Formula Foods for Special Medical Purposes".
实施案例二 Implementation Case 2
上述萎缩性胃炎非全营养配方食品还包括以重量计的下列组分: 药食两用的提取物: 栀子5g、白背三七5g、蛹虫草5g、苏子4g、香橼4g、鸡内金4g、红曲米4g、玫瑰花4g、麦芽4g、薏苡仁4g、砂仁4g、猴头菇4g、肉豆蔻4g、沙棘4g、木瓜4g、莱菔子4g、山楂3g、黄精3g、钝顶螺旋藻3g、荔枝核3g、紫苏3g、蒲公英3g、金银花2g、大枣2g、桔梗2g、佛手2g、松花粉2g、玉竹2g、乌梅2g、生姜2g、丁香2g、酵母2g、圆苞车前子壳1g、布渣叶1g、耳叶牛皮消1g、蛋白核小球藻1g、雪莲培养物1g、乳矿物盐1g、益生元350g、短肽150g、多种氨基酸100g、碳水化合物100g、有保健功能的油酯100g、碳水化合物、有保健功能的油脂、50g、维生素和矿物质25g。 The above-mentioned atrophic gastritis non-complete nutritional formula food also includes the following components by weight: extracts for both medicine and food: 5g of gardenia, 5g of Radix Notoginseng, 5g of Cordyceps militaris, 4g of perilla, 4g of citron, chicken Neijin 4g, red yeast rice 4g, rose 4g, malt 4g, coix seed 4g, Amomum 4g, Hericium erinaceus 4g, nutmeg 4g, seabuckthorn 4g, papaya 4g, radish seed 4g, hawthorn 3g, sealwort 3g, blunt 3g spirulina, 3g lychee core, 3g perilla, 3g dandelion, 2g honeysuckle, 2g jujube, 2g bellflower, 2g bergamot, 2g pine pollen, 2g polygonatum, 2g dark plum, 2g ginger, 2g clove, 2g yeast, round 1g psyllium husk , 1g cloth slag leaf , 1g auricularia psoriasis , 1g pyrenoid chlorella , 1g snow lotus culture, 1g milk mineral salt , 350g prebiotics, 150g short peptide, 100g various amino acids, carbohydrates 100g, 100g of oil with health function, carbohydrates, 50g of oil with health function, 25g of vitamins and minerals.
实施案例三 Implementation Case Three
上述萎缩性胃炎非全营养配方食品,还包括以重量计的下列组分:几种药食两用的中药提取物精华及新资源食品500g、益生元450g、短肽200g、有保健功能的油脂150g、氨基酸150g、多种维生素25g、多种矿物质25g;每100g所含有的能量应不低于295kJ(70kcal)。 The above-mentioned atrophic gastritis is not a complete nutritional formula food, but also includes the following components by weight: several medicinal and edible Chinese medicine extract essences and new resource foods 500g, prebiotics 450g, short peptides 200g, oils and fats with health care functions 150g, amino acid 150g, multivitamin 25g, multimineral 25g; the energy contained in every 100g should not be less than 295kJ (70kcal).
实施案例四 Implementation Case 4
上述萎缩性胃炎非全营养配方食品,还包括以重量计的下列组分:药食两用中药提取物精华及新资源食品500g、益生元450g,碳水化合物300g、短肽250g、氨基酸150g、多种维生素25g、多种矿物质25g;每100g所含有的能量应不低于295kJ(70kcal)。 The above-mentioned atrophic gastritis is not a complete nutritional formula food, but also includes the following components by weight: medicinal and edible traditional Chinese medicine extract essence and new resource food 500g, prebiotics 450g, carbohydrates 300g, short peptides 250g, amino acids 150g, polysaccharides 25g of vitamins and 25g of various minerals; the energy contained in each 100g should not be less than 295kJ (70kcal).
实施案例五 Implementation Case Five
上述萎缩性胃炎非全营养配方食品,还包括以重量计的下列组分:药食两用中药提取物精华及新资源食品500g、益生元480g,短肽250g、碳水化合物250g、有保健功能的油脂150g、多种维生素25g、多种矿物质25g;每100g所含有的能量应不低于295kJ(70kcal)。 The above-mentioned atrophic gastritis is not a complete nutritional formula food, but also includes the following components by weight: medicinal and edible Chinese medicine extract essence and new resource food 500g, prebiotics 480g, short peptides 250g, carbohydrates 250g, 150g of oil, 25g of multivitamins, and 25g of multiminerals; the energy contained in each 100g should not be less than 295kJ (70kcal).
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| CN105361149A (en) * | 2015-11-11 | 2016-03-02 | 成都圣弘源生物科技有限公司 | Highland barley-Chinese caterpillar fungus nutrition powder and preparation method thereof |
| CN105596901A (en) * | 2016-01-04 | 2016-05-25 | 成都富豪斯生物科技有限公司 | Orally-administered drug for treating stomach-yin insufficiency symptom and preparation method thereof |
| CN109497268A (en) * | 2019-01-03 | 2019-03-22 | 王中华 | A kind of shrimpfish Gly-His-Lys and its preparation and method of comprehensive utilization |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105361149A (en) * | 2015-11-11 | 2016-03-02 | 成都圣弘源生物科技有限公司 | Highland barley-Chinese caterpillar fungus nutrition powder and preparation method thereof |
| CN105596901A (en) * | 2016-01-04 | 2016-05-25 | 成都富豪斯生物科技有限公司 | Orally-administered drug for treating stomach-yin insufficiency symptom and preparation method thereof |
| CN109497268A (en) * | 2019-01-03 | 2019-03-22 | 王中华 | A kind of shrimpfish Gly-His-Lys and its preparation and method of comprehensive utilization |
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