CN104840632A - Lotion for external use for treating dermatophytosis and preparation method for lotion - Google Patents

Abstract

The invention discloses lotion for external use for treating dermatophytosis. The lotion is prepared from the following raw materials in parts by weight: 12-15 parts of sambucus chinensis, 12-15 parts of elsholtzia, 15-17 parts of common achyranthes herb, 15-17 parts of phryma leptostachya, 23-27 parts of arcangelisia loureiri, 17-19 parts of sansevieria, 23-27 parts of sabia japonica, 19-21 parts of herba orostachyos and 12-14 parts of medical stones. The method for preparing the lotion for external use for treating dermatophytosis comprises the following steps: a, smashing and mixing sambucus chinensis, elsholtzia, common achyranthes herb, phryma leptostachya, arcangelisia loureiri, sansevieria, sabia japonica and herba orostachyos to obtain a mixture, adding 70 percent of ethyl alcohol into the mixture according to the material-to-liquid ratio of 1 to 8, performing backflow extraction for three times, each time for 2 hours, and combining backflow liquid; concentrating into extract with the relative density of 1.28-1.32 (25 DEG C); b, preparing the medical stones into powder of 100 meshes, and uniformly mixing the powder and the extract in the step a. When the lotion is used, 15 grams are used each time; 1,500 grams of warm water is added, uniform stirring is performed, immersion is performed for 30-40 minutes, and one course of treatment includes 7 days.

Description

A kind of external-use lotion for the treatment of beriberi and preparation method thereof

Technical field

The invention belongs to Chinese medicine external agent field, be specially a kind of external-use lotion for the treatment of beriberi and preparation method thereof.

Background technology

Beriberi clinical manifestation is play vesicle, decortication or skin whitening between toe to wet soft, and also can occur erosion or pachyderma, coarse, cracking, and can spread to the sufficient sole of the foot and edge, play is itched.Can accompany local suppuration, red and swollen, pain, inguinal lymphadenopathy, even forms shank erysipelasand the secondary infection such as cellulitis.Due to the place that scratches with hands, normal infection occurs to hands the tinea manuum(fungal infection of hand and foot).Fungus grows in finger (toe) first, then become tinea unguium( tinea unguium).Fungus likes the environment of damp warm, and summer, sky overabundant heat antiperspirant, wore rubber overshoes, nylon sock person especially for fungus provides hotbed; The many improvements of the state of an illness in winter, show as skin cracks.

Western medical treatment generally uses imidazoles solution or cream, also can with Salicylic Acid Formulations etc., every day 1 ~ 2 time.Chinese traditional treatment is of a great variety, and comprise (1) dried Alumen, Cortex Phellodendri, Galla Chinensis, Os Sepiae, choosing any one kind of them, it is for subsequent use to grind into powder, is spread on affected part after cleaning foot.Be applicable to erosive type.(2) Radix Sophorae Flavescentis, Cortex Dictamni ` Herba Portulacae, each 30 grams of Herba Plantaginis, each 15 grams of Rhizoma Atractylodis, Cortex Phellodendri, decocts and wash 1-2 time every day.Apply to vesicle or when having infection and have good result.(3) white Flos Impatientis 30 grams, Fructus Gleditsia 30 grams, 15 grams, Pericarpium Zanthoxyli, optional-kind, put into half jin of vinegar, soak after one day, in foot bath 20 minutes just before going to bed every night.Continuous treatment 7 days, diagonalization type has good effect.(4) Fructus Chaenomelis 30 grams, 30 grams, Radix Glycyrrhizae.To add medicine to decocting extracting juice, foot bath 5 ~ 10 minutes after Hou Wen, every day 2 times, every day 1 dose, the method such as continuous 5 ~ 10 days.

Summary of the invention

The object of this invention is to provide a kind of external-use lotion for the treatment of beriberi and preparation method thereof.

The present invention treats the external-use lotion of beriberi, is made up of the raw material of following parts by weight: Herba Sambuci Chiensis 12 ~ 15 parts, Herba Moslae 12 ~ 15 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 15 ~ 17 parts, Herba speranskiae tuberculatae 15 ~ 17 parts, Caulis Arcangelisiae 23 ~ 27 parts, Folium Sansevieriae Trifasclatae 17 ~ 19 parts, Caulis Sinomenii 23 ~ 27 parts, Herba Orostachyos 19 ~ 21 parts, Maifanitum 12 ~ 14 parts.

As optimization, the external-use lotion of this treatment beriberi; Be made up of the raw material of following parts by weight: Herba Sambuci Chiensis 13 parts, Herba Moslae 14 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 16 parts, Herba speranskiae tuberculatae 16 parts, Caulis Arcangelisiae 25 parts, Folium Sansevieriae Trifasclatae 18 parts, Caulis Sinomenii 26 parts, Herba Orostachyos 20 parts, Maifanitum 13 parts.

Prepare the method for this treatment beriberi external-use lotion, comprise the following steps:

A, by the Herba Sambuci Chiensis of described parts by weight, Herba Moslae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba speranskiae tuberculatae, Caulis Arcangelisiae, Folium Sansevieriae Trifasclatae, Caulis Sinomenii, Herba Orostachyos pulverize after mixing, by solid-liquid ratio 1:8, add 70% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (25 DEG C);

B, the Maifanitum of described parts by weight is made 100 object powder, with the extractum mix homogeneously in step a.During use each 15 grams, add 1500 grams of warm water and stir, soak 30 ~ 40 minutes, 7 days courses for the treatment of.

In the external-use lotion component of this treatment beriberi, Herba Sambuci Chiensis promoting blood circulation to remove blood stasis, soothing liver and strengthening spleen, dispelling, collateral-activating, diaphoresis diuresis; For traumatic injury, for acute viral hepatitis, rheumatalgia, dislocation, fracture, oedema due to nephritis, beriberi edema, urticaria.Herba Moslae energy relieving the exterior syndrome by diaphoresis, removing dampness for regulating stomach, inducing diuresis to remove edema; Cure mainly Xia Yue sense cold fluid-retention cold, have a headache and fever, aversion to cold is lossless, and the feeling of stuffiness in chest is suffered from abdominal pain, vomiting and diarrhoea, edema, beriberi.Radix achyranthis asperae (Herba Achyranthis Asperae) heat clearing away, induces sweat, and diuretic is invigorated blood circulation; Cure cold heating, dysentery, malaria, laryngalgia, beriberi, gonorrhea, edema, traumatic injury.Herba speranskiae tuberculatae expelling wind and removing dampness, removing toxic substances pain relieving; For rheumatic arthritis; Sore swollen toxin is controlled in external.Caulis Arcangelisiae clearing away heat-damp and promoting diuresis, removing toxic substances pain relieving; For preventing influenza, leptospirosis, control acute gastroenteritis, bacillary dysentery, tonsillitis, bronchitis, malaria; Eye conjunctivitis is controlled in external, skin eczema, impetigo, vaginitis.Folium Sansevieriae Trifasclatae heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation; For cold cough, bronchitis, traumatic injury; Carbuncle pyogenic infections from tumour or sore is controlled in external, venom.Caulis Sinomenii expelling wind and removing dampness; Promoting blood circulation and detoxication; Main air pain of dampness syndrome; The arthroncus of knee; Edema; Foot gas; Treating swelling and pain by traumatic injury; Fracture; Deep abscess; Osteomyelitis; Suppurative arthritis; Spondylitis; Sore swollen toxin; Skin pruritus.Herba Orostachyos heat-clearing and toxic substances removing, hemostasis, dampness removing, detumescence; Control haematemesis, epistaxis, dysentery, hepatitis, malaria, pyretic stranguria, hemorrhoid, eczema, carbuncle poison, furuncle, soup fire is burnt.Maifanitum is a kind of special nonmetal mineral resource, its likeness in form plaque-like yellow or in vain, quite like wheat grain; Medical stone powder enters Chinese medicine, and the water soaked can be drunk, and also for taking a shower, can have the drug effect of body-building and life lengthening.

The present invention treats the external-use lotion of beriberi, all components compatibilities, and synergism is remarkable, there is effect of dispelling, collateral-activating, inducing diuresis to remove edema, clearing away heat-damp and promoting diuresis, disinfecting detoxifying, very outstanding as external-use lotion treatment beriberi effect, without anaphylaxis, effective percentage reaches 97.83%.

Detailed description of the invention

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.

Embodiment 1:a, by Herba Sambuci Chiensis 130 grams, Herba Moslae 140 grams, Radix achyranthis asperae (Herba Achyranthis Asperae) 160 grams, Herba speranskiae tuberculatae 160 grams, Caulis Arcangelisiae 250 grams, Folium Sansevieriae Trifasclatae 180 grams, Caulis Sinomenii 260 grams, Herba Orostachyos 200 grams pulverize after mixing, by solid-liquid ratio 1:8, add 70% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (25 DEG C);

B, Maifanitum 130 is restrained into 100 object powder, with the extractum mix homogeneously in step a.During use each 15 grams, add 1500 grams of warm water and stir, soak 30 ~ 40 minutes, twice on the one, 7 days courses for the treatment of.

Embodiment 2:a, by Herba Sambuci Chiensis 120 grams, Herba Moslae 120 grams, Radix achyranthis asperae (Herba Achyranthis Asperae) 150 grams, Herba speranskiae tuberculatae 150 grams, Caulis Arcangelisiae 230 grams, Folium Sansevieriae Trifasclatae 170 grams, Caulis Sinomenii 230 grams, Herba Orostachyos 190 grams pulverize after mixing, by solid-liquid ratio 1:8, add 70% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (25 DEG C);

B, Maifanitum 120 is restrained into 100 object powder, with the extractum mix homogeneously in step a.During use each 15 grams, add 1500 grams of warm water and stir, soak 30 ~ 40 minutes, twice on the one, 7 days courses for the treatment of.

Embodiment 3:a, by Herba Sambuci Chiensis 150 grams, Herba Moslae 150 grams, Radix achyranthis asperae (Herba Achyranthis Asperae) 170 grams, Herba speranskiae tuberculatae 170 grams, Caulis Arcangelisiae 270 grams, Folium Sansevieriae Trifasclatae 190 grams, Caulis Sinomenii 270 grams, Herba Orostachyos 210 grams pulverize after mixing, by solid-liquid ratio 1:8, add 70% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (25 DEG C);

B, Maifanitum 140 is restrained into 100 object powder, with the extractum mix homogeneously in step a.During use each 15 grams, add 1500 grams of warm water and stir, soak 30 ~ 40 minutes, twice on the one, 7 days courses for the treatment of.

Pertinent clinical data is as follows: physical data: totally 368 routine beriberi patients, male 238 example, women 130 example, 17 ~ 61 years old age, 36.7 years old mean age, the course of disease 2 days ~ 3 years; Be divided into two groups at random, treatment group 184 example: matched group 184 example: two groups of patient profiles are basically identical, without significant difference (P>O.05), have comparability.

Diagnostic criteria: all patients all meet diagnostic criteria in " Chinese medical disease Standardization of diagnosis and curative effect ", symptom is between toe, grain of rice size appears in sufficient edge, vola, and deeply in property vesicle, evacuate or distribute in groups, kitchen wall is thicker, and content is limpid, not easily breaks.Dry desquamation after a few days, mutually merges and forms kerionic vesicle, tear kitchen wall off, visible honeycomb substrate and the rotten to the corn face of cerise, violent pruritus.

Therapeutic Method: treatment group accepts the external-use lotion clinical treatment for the treatment of beriberi in embodiment 1, each 15 grams of used time, adds 1500 grams of warm water and stirs, soak 30 ~ 40 minutes, every day twice, 7 days courses for the treatment of.Matched group accepts clotrimazole cream clinical treatment, is coated onto affected part after foot bath, every day twice, within 7 days, is a course for the treatment of, observe the curative effect after the course for the treatment of.

Curative effect determinate standard: recovery from illness: skin lesion disappears, subjective symptoms disappears, selective examination negative fungal examination.Effective: skin lesion disappears more than 40%, and subjective symptoms obviously alleviates.Invalid: skin lesion disappears and is less than 40%, subjective symptoms is without being clearly better, and fungus microscope examination is positive.Two groups of relevant efficacy results of patient are in table 1.

Claims (3)

1. treat an external-use lotion for beriberi, it is characterized in that being made up of the raw material of following parts by weight: Herba Sambuci Chiensis 12 ~ 15 parts, Herba Moslae 12 ~ 15 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 15 ~ 17 parts, Herba speranskiae tuberculatae 15 ~ 17 parts, Caulis Arcangelisiae 23 ~ 27 parts, Folium Sansevieriae Trifasclatae 17 ~ 19 parts, Caulis Sinomenii 23 ~ 27 parts, Herba Orostachyos 19 ~ 21 parts, Maifanitum 12 ~ 14 parts.

2. require the external-use lotion for the treatment of beriberi described in 1 according to power; It is characterized in that; Be made up of the raw material of following weight fraction: Herba Sambuci Chiensis 13 parts, Herba Moslae 14 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 16 parts, Herba speranskiae tuberculatae 16 parts, Caulis Arcangelisiae 25 parts, Folium Sansevieriae Trifasclatae 18 parts, Caulis Sinomenii 26 parts, Herba Orostachyos 20 parts, Maifanitum 13 parts.

3. prepare a method for the treatment of beriberi external-use lotion described in claim 1, it is characterized in that comprising the following steps:

A, by the Herba Sambuci Chiensis of described parts by weight, Herba Moslae, Radix achyranthis asperae (Herba Achyranthis Asperae), Herba speranskiae tuberculatae, Caulis Arcangelisiae, Folium Sansevieriae Trifasclatae, Caulis Sinomenii, Herba Orostachyos pulverize after mixing, by solid-liquid ratio 1:8, add 70% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (25 DEG C);

B, the Maifanitum of described parts by weight is made 100 object powder, with the extractum mix homogeneously in step a.