CN104822880B - 用于医疗灭菌包装的在线处理的可密封和可剥离的医疗纸 - Google Patents
用于医疗灭菌包装的在线处理的可密封和可剥离的医疗纸 Download PDFInfo
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Abstract
公开了一种用于医疗灭菌包装的医疗纸的制造方法与装置,医疗纸和医疗灭菌包装。由含纤维素纤维的纤维基底和任选地合成纤维形成具有相对的第一面和第二面的纸幅。在在线形成纸幅的情况下,在第一面上施加增强材料,并挤压到纸幅的结构内部,以便增加该结构的抗脱层性性能。在在线形成纸幅的情况下,在纸幅的第二面上施加密封材料。
Description
技术领域
本发明一般地涉及用于医疗灭菌包装的在线处理的可密封和可剥 离的医疗纸。
背景技术
需要医疗灭菌包装储存和运输各种灭菌的医疗器件。2006年7月 的NF EN ISO 11607-1在附录A中描述了使用这一标准术语,影响医 疗灭菌包装设计或医疗包装系统的各种因素。通过环氧乙烷气体 (EO),γ辐射线(γ),电子束(e-束),蒸汽高压釜,或低温氧化灭菌工艺, 进行典型的灭菌处理。若通过EO,蒸汽或氧化工艺进行灭菌,则包 装提供有无菌阻挡系统,所述无菌阻挡系统具有可渗透组分,以允许 灭菌气体进入,杀灭微生物,并在没有显著残留浓度情况下逃逸。在 大多数情况下,该无菌阻挡系统具有“顶部网幅(top-web)”,“底部网 幅”,以及将网幅连接在一起的机构。在其中要求可剥离密封的情况下, 采用密封层,允许将两层密封在一起。密封层(它典型地通过离线涂布 生产)常规地施加到可渗透的网幅上。当今,许多薄膜掺入密封层作为 (a)薄膜结构内的层。在要求焊接密封的情况下,要求网幅的相容性, 以允许通过加热或压力连接。
无菌阻挡系统多孔网幅常常由医疗纸制成,所述医疗纸被制造为 不含污染物或微生物,且被加工以闭合微生物可能穿过的大的孔隙, 同时留下灭菌剂,例如EO气体的充足的渗透性。医疗纸应当满足预 定的最小物理要求,例如空气渗透,拉伸强度,抗撕裂性,和爆破强 度。在前面提及的ISO标准的5.1.7和5.1.9段落中还列出了各种其 他要求。后一段落列出了密封的要求(若形成任何密封的话)和剥离-开 放特征。剥离-开放应当是连续并均匀的且没有可能影响消毒口和外观 的脱层或撕裂材料。还通过所讨论的ISO标准,定义其他要求,例如 微生物阻挡性能。使用离线或在线处理,生产用于医疗灭菌包装的可 密封和可剥离医疗纸。在线处理省去了对随后工艺步骤的需求,且节 能,同时增加复杂度和处理可靠度的特定要求,以避免产生废物和耗 能。例如,WO0231248(A2)公开了通过在纸浆内混合含可悬垂的饱和 剂组分和额外的饱和剂聚合物的组合物,浸渍或饱和纸幅,生产这种 纸张的方法。该组合物应当在纤维网幅和基础组分聚合物材料之间提 供加强的密封强度。通过饱和纸张,期望能直接密封到在纸幅中的基 础组分内所使用的材料上,结果不需要独立的离线涂布。然而,与正 常来源的纸张材料相比,用这种组合物饱和纸张消耗更加昂贵的相对 大量的技术化学品。而且,这种聚合物可由油生产,且妨碍了纸张的 回收以供采用可商购的纸张循环技术,生产其他等级的纸张或者纸板。
离线的涂布基方法可提供再生天然材料的更加有效的用途。在一 种技术中,首先在造纸机内形成纸幅,干燥,并通过用施胶压机,在 纸幅的两面上施加某种粘合剂,在线施胶替代纸浆添加剂基浸渍,当 在操作中施胶压机在网幅的两面上形成粘合剂材料的池塘(pond)和这 些池塘在网幅的两个边缘处自由地混合时。然后干燥纸幅并收卷到机 械卷内。随后,在纸幅上离线涂布热密封层。在线施加粘合剂有助于 避免撕裂,结果释放可能影响包装医疗物品的消毒口和外观的纤维, 特别地纤维素材料,当在增强材料层上形成热密封层时。在热密封层 内和/或在热密封层和增强材料层之间的界面上发生剥离。然而期望避 免作为相对昂贵工序的离线涂布。
形成用于医疗灭菌包装的可剥离医疗纸的一种已知的技术通过使 用离线挤出聚乙烯,在纸幅上施加热密封层。
本发明的目的是提供医疗灭菌包装用的生态和经济的可密封且可 剥离的医疗纸,和包含它们的包装,以消除或减少涉及在先已知的这 种纸张与包装的一些缺点和生产它的方法,或者提供新的技术替代。
发明概述
根据本发明的第一例举的方面,提供制造用于医疗灭菌包装的医 疗纸的制造方法,该方法包括:
形成含纤维素纤维的纤维基底的纸幅,该纸幅包括相对的第一面 和第二面;
形成纸幅的情况下,在线施加增强材料在第一面上,并将增强材 料压入该纸幅的结构内,以便增加该结构的抗脱层性能;和
形成纸幅的情况下,在线施加密封材料到纸幅的第二面上。
在这一文献中,术语“纸张”是指在结构内含纤维素纤维和任选地 最多30wt%合成纤维的湿法成网材料的片材,其中纤维键合到彼此 上,形成纸张状结构。合成纤维可以是合成的短切纤维。
纸幅可由纤维基底的单层组成。
可使用成形部分进行成形。成形部分可包括长网成形器的成形网; 间隙式成形器;吸水箱;和脱水箔中的至少一个。
根据本发明的第二例举的方面,提供一种造纸装置,该装置包括:
为形成含纤维素纤维的纤维基底的纸幅而构造的成形部分,该纸 幅包括相对的第一面和第二面;
为施加增强材料到第一面上而构造的在线增强材料施涂器;
为挤压增强材料到纸幅结构内部而构造的在线压机,以便在纸幅 结构当中增加抗脱层性能;和
为施加密封材料到纸幅的第二面上而构造的在线密封材料施涂 器。
在线增强材料施涂器,在线密封材料施涂器和在线压机可以是相 同表面处理站的一部分。
根据本发明的第三例举的方面,提供用于医疗灭菌包装的含纤维 素纤维的纤维基底的医疗纸,该纸张具有相对的第一面和第二面且包 括:
通过第一面施加增强材料到纸张结构内部,以便通过从第一面施 加,在该纸幅的结构当中增加抗脱层性性能能,和导致纸张具有不均 匀的增强材料的z-方向分布;和
在纸张的第二面上的密封材料。
根据第四例举的方面,提供一种医疗灭菌包装,它包括:
第三例举方面的医疗纸;和
通过施加到纸张的第二面上的密封材料密封医疗纸,为覆盖医疗 器件而构造的包装元件。
根据第五例举的方面,提供一种系统,它包括:
第四例举方面的医疗灭菌包装;和
通过施加到纸张的第二面上的密封材料,在包装内密封的医疗器 件。
在下述详细说明中和在所附的独立权利要求中列出了本发明的不 同的非限制性例举方面和实施方案。应当理解,相应的实施方案可自 由地应用到其他实施方案和实施例的方面上。
附图简述
参考附图描述本发明的一些例举实施方案,其中:
图1示出了根据本发明的一个实施方案中的造纸机的一些基本元 件的示意图;
图2示出了作为截面观察的在其内具有医疗装置的医疗灭菌包 装,且为了阐述目的,所述截面具有大大地放大的厚度;和
图3示出了从底部观察的图2的医疗灭菌包装。
详细说明
在下述说明中,相同的参考标记表示相同的元件。
图1示出了根据本发明的一个实施方案的造纸机100的一些基本 元件的示意图。造纸机100包括具有网前箱112和线网部分114的成 形部分110。成形部分112接收纸浆,所述纸浆是纤维和任选的填料 和其他材料的水悬浮液,并通过纸浆内纤维的湿法成网,形成纸幅 120。纸幅具有第一面120a和第二面120b。在这一实例中,第一面 120a被称为功能面。注意第一面不需要在如图1所示的顶部上,仅仅 为了阐述的目的。
造纸机100进一步包括第一干燥部分130,其中通过使用,例如 通过挤压(例如压机辊隙),和通过蒸发(例如,炽热圆筒,红外干燥器), 从纸幅120中除去水。
在第一干燥部分的下游,造纸机100包括表面处理站140,所述 表面处理站140包括第一表面处理单元142和第二表面处理单元144 以供通过它的各自的第一面和第二面,处理纸幅120,将纸幅120转 化成加工过或表面处理过的纸幅120'。
要理解,例如通过对纸幅表示不同的参考标记,同时自然地连续 改变结构和特别地水含量,说明不了通过干燥和压延引起的纸幅内的 常见变化。而且,在本发明的上下文中,术语“面”可理解为“表面”。 进一步地,应当理解,各种元件,例如表面处理站的取向和位置在每 一技术的已知范围内可自由地调节。例如,表面处理站140以便纸幅 垂直,水平或倾斜地穿过它,和纸幅也可转向进入到表面处理站140 内和/或离开表面处理站140。
第一表面处理单元142和第二表面处理单元144在纸幅120的第 一面和第二面120a,120b上施加各自的增强材料143和密封材料145。 纸幅120然后经过压机辊隙,其中增强材料143被挤压到纸幅120 内。令人惊奇地,已经意识到,在纸幅120内部,增强材料143可在 纸幅当中增加抗脱层性性能,甚至当仅仅通过纸幅的一面施加时。认 为这由下述机理引起:其中增强材料在压机辊隙诱导的压力下渗透到 纸幅的结构内部的孔隙中,且在没有任何游离水(即在纤维和纸幅120 的其他颗粒之间驻留的水)的情况下部分扩散。
表面处理站140例如是薄膜转移站。在备选的其他例举的实施方 案中,表面处理站140包括选自下述中的一个或多个单元:喷雾涂布 单元;气刀式涂布单元;和幕涂单元;和将增强材料143挤压到纸幅 120内的挤压单元。
在表面处理站之后,即在其下游,造纸机100包括第二干燥部分 150和在表面处理过的纸幅120'内缠绕的卷线机150。
在优选的例举实施方案中,纸幅仅仅用表面处理站140表面处理 一次,结果一个压机辊隙同时挤压增强材料143和密封材料145。按 照这一方式,造纸机不需要包含大于两个干燥部分。
要理解,每一个所描述的部分是在线单元。换句话说,这些单元 在纸张上操作,同时它在造纸机内成形,或者纸张没有转移到例如机 械辊或卷绕辊上离线加工。
考虑所讨论的纸张等级和可获得的来源,使用普通的造纸知识, 构造成形部分110以及造纸机的其他主要部件。
在图1所示的例举实施方案中,提供一个表面处理站140。在另 一例举的实施方案中,提供两个或更多个表面处理站,每一个接着下 游的干燥部分。表面处理站可以具有相同或不同的类型。在多站式实 施方案中,可在一个或多个表面处理站处,可能地在每一个表面处理 站处,表面处理纸幅120的仅仅一面。
在具有两个或更多个表面处理站的进一步的例举的实施方案中, 首先在一个或多个步骤中进行两面增强处理,且强调在第一面120a 具有例如80-20或70-30的分布,以便通过第一面挤压的增强材料 143可在纸幅120的结构当中增加抗脱层性能,同时进一步的增强材 料从第二面进入到纸幅120的结构内部。随后用密封材料145表面处 理纸幅120的第二面。
在一个例举的实施方案中,造纸机100还包括在一个或多个施胶 或涂布站之前的一个或多个机器压延机。
构造造纸机100,生产用于医疗包装的可热密封的纸张,以允许 灭菌并维持包装的医疗器件(MD)无菌直到最终使用。必须提供合适的 密封强度,以避免在灭菌、储存和运输期间任何偶尔的打开包装,和 清洁的可剥离性,以允许就在MD的使用之前,无菌打开。可以便纸 张符合用于国际应用的ISO 11607-1并符合用于欧洲应用的互补的垂 直部件EN868。
通过施加密封材料145,采用在线加工,生产纸幅120,当打开 密封件以便能目测检查包装保持其完整性时,产生篡改证据,以便可 检验MD的无菌性,直到包装的最终使用。篡改证据可以例如是指一 些密封材料从密封层转移到相对的材料,例如PE薄膜或纤维网上。 密封材料的转移在密封件的大多数或全部长度上可以是连续的。
造纸机100能在线双面处理纸幅120。以便所生产的纸张在一面 上(例如热)可密封和可剥离。
在这一文献中,表面处理和涂布可互换使用,除非另有说明,因 为该差别常常有点不确定。
熟练的纸张制造者知道如何执行本领域技术人员所已知操作的造 纸机的正常部件。因此,接下来将进一步详细地描述涉及纸幅120的 表面处理的结构和操作。在图1中所示的例举实施方案用于阐述一些 执行操作。
图2示出了在其内具有医疗器件220的原料灭菌包装200,且为 了阐述目的,所述截面具有大大地放大的厚度。图2还示出了增强材 料143从第一面120a穿透纸幅到达第二面。图2进一步示出了可剥离 的密封层145和包装元件210,此处所述包装元件210是挠性PE薄膜, 它通过密封区域230,经其边缘连接到密封层145上。
在健康护理设施中医疗包装的密封强度的最小值,对于蒸汽灭菌 来说,应当是1.5N/15mm,和对于其他类型的灭菌来说,应当是1.2 N/15mm,当根据EN 868-5(2009)附录D测试时。因此优选生产该医 疗灭菌包装。
图3示出了从底部观察的图2的医疗灭菌包装。图3清楚地示出 了围绕包装的医疗器件220的密封区域230。一旦剥离开包装,则一 些密封层145将分开或者从医疗纸转移到第二网幅上,结果即使再胶 合该包装元件(在这一实例中,PE薄膜),将留下连续可视的痕迹作为 篡改证据。
另一方面,与当通过剥离掉纸张,打开包装时纸张经历的相比, 增强材料143提供具有较大抗脱层性能的纸张结构。
在例举的实施方案中,在纸幅120的第一面120a上施加的增强 材料的用量和干物质含量是变化的,这取决于所讨论的材料。例如, 干燥量范围可以是0.2wt%-8wt%和干物质含量可以是4wt%-20 wt%。符号wt%是指重量百分比或质量分数,即给定组分的重量对总 质量(包括所讨论的组分,当针对干燥纸张,即处于平衡湿度的纸张计 算时)之比。
在例举的实施方案中,所生产的纸张的基重为40g/m2-120g/m2, 例如63,5g/m2,当在平衡湿度下测量时。
测量平衡湿度是指正常的纸张测试条件,即23℃,50%相对湿度, 标准大气压力。
在例举的实施方案中,施加密封材料到干物质含量为35wt%-40 wt%的纸幅上。
纸浆
采用纤维素纤维和任选地采用最多30wt%合成纤维,例如合成短 切纤维,制造纸浆。应当注意,纤维素并不指代仅仅化学制浆,而且 也可例如通过机械制浆形成的纤维素和/或半纤维素纤维。在例举的实 施方案中,采用非循环,即未加工的漂白纸浆,制造纸浆。纸浆的主 要成分是100wt%-0wt%vs 0wt%-100wt%的软木(例如,松木或 云杉)和硬木(例如,桦树和桉树),优选20/80-50/50分布的混合物,这 分别在软木和硬木的干重下测量。这一分布是指纤维素纤维的分布。
湿端考虑因素(WET END CONSIDERATIONS)
可通过下述,加工纸幅或纸浆:
-例如采用松香或烷基烯酮二聚体(AKD)和/或链烯基琥珀酸酐 (ASA)施胶
-通过在纸浆内添加例如聚丙烯酸类酯(PAE)或聚丙烯酸酯(PAAE) 的湿强支持剂
-例如通过在纸浆内添加淀粉;羧甲基纤维素(CMC);和/或合成 粘合剂的增强。
表面处理材料
可选择增强材料,以便考虑密封强度,纸张获得充足的抗脱层性 性能,结果当剥离开含该纸张的医疗包装时,该纸张不脱层,以便包 装的内容物可能被撕裂的纤维污染。影响增强材料选择的因素一般地 是纸浆的组成,湿端施胶剂含量,挤压到纸幅的结构内部的增强材料 量,在施加增强材料时纸幅的光滑度和孔隙率,增强材料的粘度,和 挤压条件。可例如从淀粉;聚乙烯醇(PVOH);合成粘合剂,例如丙烯 酸丙烯酸类粘合剂;丙烯酸,苯乙烯丁二烯(SB),丙烯酸酯苯乙烯丁 二烯,丙烯酸丁酯乙酸乙烯酯,羧化SB,乙酸乙烯酯(VA),乙酸乙 烯酯丙烯腈丙烯酸类,乙酸乙烯酯丙烯酸酯,氯乙烯(VC),聚氯乙烯 (PVC),聚氨酯粘合剂;和它们的任何共聚物或组合中选择增强材料。
根据将生产的医疗纸的应用,选择热密封材料。在例举的实施方 案中,可例如从乙烯乙酸乙烯酯共聚物;乙烯丙烯酸共聚物;聚乙烯 共聚物蜡;聚丙烯蜡;或其任何组合中选择热密封材料。在例举的实 施方案中,热密封材料还包括增稠剂以供增加粘度到150-300cps并 保持处理剂在片材(CMC,淀粉,PVOH,合成增稠剂)顶部上,即避免热 密封材料渗透到纸幅120的结构内部。
在一个特别的例举实施方案中,如下所述制造医疗包装:
·备用纸:
οISO 536每平方米克重=63,5g/m2
οISO 1924-2:拉伸强度MD=6kN/m
οISO 1924-2:拉伸强度CD=2.8kN/m
οISO 2758:爆破强度=330kPa
οISO 1974:撕裂强度MD=455mN
οISO 1974:撕裂强度CD=540mN
·原纸
ο60g/m2精制到27°SR
ο47.7g/m2未加工的漂白硬木:桦树
ο11.9g/m2未加工的漂白硬木:松树
ο0.3g/m2在基础成分内的助剂以供内部施胶,湿强度和纤维粘结
·面1:增强处理
ο干物质含量=5%
ο化学品:淀粉+AKD 0.1g/m2
ο粘度:采用Brookfield 100T,调节到20cps
ο干燥涂层重量=0.5g/m2
ο施加和挤压:例如采用在线Sym-sizer站的薄膜转移工艺。
■光滑棒和聚氨酯(PU)覆盖的辊隙
·面2:热密封处理:
ο干物质含量=38%
ο化学品:EVAc+助增稠剂CMC的分散体
ο粘度:采用Brookfield 100T,调节到180cps
ο总的干燥涂层重量=3g/m2
ο工艺:薄膜转移与用增强材料处理面1基本上同时
■开槽棒和PU覆盖的辊隙
·包装:
ο贴着用于医疗包装,例如ESE 12/50的 医疗聚乙烯(PE)可热密封薄膜,密封纸张的可热密封的一面
ο密封条件:150℃,500N/10cm2,1秒
ο密封强度:2N/15mm
ο剥离量:清洁剥离和篡改证据
在另一特别的例举实施方案中,如下所述制造医疗包装:
·备用纸:
οISO 536每平方米克重=88g/m2
οISO 1924-2:拉伸强度MD=7.0kN/m
οISO 1924-2:拉伸强度CD=3.6kN/m
οISO 2758:爆破强度=370kPa
οISO 1974:撕裂强度MD=560mN
οISO 1974:撕裂强度CD=630mN
·原纸=80g/m2,精制到25°SR
ο28g/m2未加工的漂白硬木:桦树
ο28g/m2未加工的漂白硬木:松树
ο14g/m2PET合成纤维5mm
ο0.3g/m2在基础成分内的助剂以供内部施胶,湿强度和纤维粘结
·面1:增强处理
ο干物质含量=45%
ο化学品:丙烯酸类胶乳(Tg=-13℃)
ο粘度:采用Brookfield 100T,20cps
ο干燥涂层重量=10g/m2
ο施加和挤压:例如采用在线双HSM站的薄膜转移工艺。
■光滑棒和聚氨酯(PU)覆盖的辊隙
·面2:热密封处理:
ο干物质含量=38%
ο化学品:EVAc+增稠剂的分散体:采用Brookfield 100T,调 节到180cps
ο总的干燥涂层重量=8g/m2
ο工艺:薄膜转移与用增强材料处理面1基本上同时
■开槽棒和PU覆盖的辊隙
·包装:
ο密封/剥离:贴着用于医疗包装,例如ESE 12/50 的医疗聚乙烯(PE)可热密封薄膜,密封纸张的可热密封面。
ο密封条件:150℃,500N/10cm2,1秒
ο密封强度:3.5N/15mm
ο剥离量:清洁剥离和篡改证据
在一个例举的实施方案中,使用冷密封材料而不是热密封材料, 在包装内密封纸张。压力-密封材料例如是天然橡胶。
列出了各种实施方案。应当理解,在这一文献中,措辞包括,包 含和含有各自用作开放式表达,且不意欲排除。
通过本发明特定实施方式和实施方案的非限制性实施例,发明人 实施发明目前考虑的最佳方式的全面和信息性说明,从而提供前述说 明。然而,对于本领域技术人员来说,清楚的是本发明没有限制到前 面列出的实施方案的细节上,而是在没有偏离本发明特征情况下,本 发明可在使用相当方式的其他实施方案中,或者在不同实施方案的组 合中实施。
此外,可利用本发明前面公开的实施方案的一些特征,在没有相 应使用其他特征的情况下突出优势。正因为如此,前述说明应当被视 为仅仅阐述本发明的原理,而不是对本发明限制。因此,本发明的范 围仅仅通过所附的专利权利要求来限制。
Claims (17)
1.一种用于医疗灭菌包装的医疗纸的制造方法,该方法包括:
形成含纤维素纤维的纤维基底的纸幅,该纸幅包括相对的第一面和第二面;
在形成纸幅的情况下,在线施加增强材料在第一面上,并将增强材料压入该纸幅的结构内,以便在该纸幅的结构当中增加该结构的抗脱层性能;和
在形成纸幅的情况下,在线施加密封材料到纸幅的第二面上;其中基本上同时施加增强材料和施加密封材料。
2.根据权利要求1的方法,其中在施加增强材料之后和施加密封材料之后和在用任何干燥机对第一面和第二面之一进行干燥之前进行挤压。
3.根据权利要求1或2的方法,其中通过两个滚筒的间隙进行挤出。
4.根据权利要求1或2的方法,其中通过在挤压增强材料之前在第一面上施加0.3干重%至8干重%的增强材料施加增强材料。
5.根据权利要求1或2的方法,其中通过施加2.5wt%-10wt%的密封材料,将密封材料施加到纸幅的第二面上。
6.根据权利要求1或2的方法,其中密封材料是热密封材料,包括下述中的任何一种或多种:乙烯乙酸乙烯酯共聚物;乙烯丙烯酸共聚物;聚乙烯蜡和共聚物;和聚丙烯蜡和共聚物。
7.根据权利要求6的方法,其中在纸幅的第二面上施加之前将热密封材料的粘性调节到150cps-400cps,以便防止热密封材料渗透到纸幅的结构内。
8.根据权利要求1或2的方法,其中通过薄膜转移、喷涂、气刀式涂布或幕涂,在纸幅上施加密封材料。
9.根据权利要求1或2的方法,其中形成纸幅,以包含内部施胶剂以供降低吸水。
10.根据权利要求9的方法,其中内部施胶剂包括松香;烷基烯酮二聚体;和链烯基琥珀酸酐中的至少一种。
11.根据权利要求1或2的方法,其中形成纸幅,以包含湿强剂以供增加纸幅的湿强特征。
12.根据权利要求11的方法,其中湿强剂包括聚丙烯酸类酯或聚丙烯酸酯中至少一种。
13.一种医疗纸制造装置,该装置包括:
为形成含纤维素纤维的纤维基底的纸幅而构造的成形部分,该纸幅包括相对的第一面和第二面;
为施加增强材料到第一面上而构造的在线增强材料施涂器;
为挤压增强材料到纸幅结构内部而构造的在线压机,以便在纸幅结构当中增加抗脱层性能;和
为施加密封材料到纸幅的第二面上而构造的在线密封材料施涂器。
14.一种用于医疗灭菌包装的含纤维素纤维的纤维基底的医疗纸,该纸张具有相对的第一面和第二面且包括:
通过第一面施加到纸张结构内部的增强材料,使得通过从第一面施加,在该纸幅的结构当中增加抗脱层性能,和导致纸张具有不均匀的增强材料的z-方向分布;和
在纸张的第二面上的密封材料。
15.根据权利要求14的医疗纸,其中构造密封材料,当打开由所施加的密封材料随后形成的密封时,产生篡改证据。
16.一种医疗灭菌包装,它包括:
权利要求14或15的医疗纸;和
为覆盖医疗器件而构造的包装元件,该医疗器件,通过施加到纸张的第二面上的密封材料而与医疗纸隔绝。
17.一种系统,它包括:
权利要求16的医疗灭菌包装;和
通过施加到纸张的第二面上的密封材料,在包装内密封的医疗器件。
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CN106012688B (zh) * | 2016-07-26 | 2017-07-04 | 浙江恒达新材料股份有限公司 | 一种医疗阻菌包装用纸制备工艺 |
CN106436431B (zh) * | 2016-10-21 | 2018-08-07 | 陕西科技大学 | 一种高透气性无菌包装用纸的制备方法 |
JP6975613B2 (ja) * | 2017-10-26 | 2021-12-01 | 株式会社巴川製紙所 | 滅菌袋用原紙および滅菌袋 |
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CN109602450B (zh) * | 2019-01-29 | 2021-04-30 | 北京大学第三医院(北京大学第三临床医学院) | 一种超声腔内探头隔离及导声一体化装置 |
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