CN104817652A - Method for producing high-purity inulin by using chromatographic separation technology - Google Patents
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- 229920001202 Inulin Polymers 0.000 title claims abstract description 44
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 title claims abstract description 44
- 229940029339 inulin Drugs 0.000 title claims abstract description 44
- 238000005516 engineering process Methods 0.000 title claims abstract description 15
- 238000013375 chromatographic separation Methods 0.000 title claims abstract description 12
- 238000004519 manufacturing process Methods 0.000 title abstract description 5
- 238000000034 method Methods 0.000 claims abstract description 20
- 230000008569 process Effects 0.000 claims abstract description 8
- 238000004140 cleaning Methods 0.000 claims abstract description 4
- 238000005406 washing Methods 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 33
- 238000000926 separation method Methods 0.000 claims description 15
- 240000008892 Helianthus tuberosus Species 0.000 claims description 14
- 235000003230 Helianthus tuberosus Nutrition 0.000 claims description 14
- 239000011347 resin Substances 0.000 claims description 11
- 229920005989 resin Polymers 0.000 claims description 11
- 238000010612 desalination reaction Methods 0.000 claims description 9
- 238000009792 diffusion process Methods 0.000 claims description 9
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 9
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
- 238000004587 chromatography analysis Methods 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 6
- 238000001694 spray drying Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 150000001768 cations Chemical class 0.000 claims description 5
- 239000000049 pigment Substances 0.000 claims description 5
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 3
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 3
- 238000010521 absorption reaction Methods 0.000 claims description 3
- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 150000001450 anions Chemical class 0.000 claims description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
- 235000011089 carbon dioxide Nutrition 0.000 claims description 3
- 239000003729 cation exchange resin Substances 0.000 claims description 3
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 238000005354 coacervation Methods 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 239000012634 fragment Substances 0.000 claims description 3
- 239000011591 potassium Substances 0.000 claims description 3
- 229910052700 potassium Inorganic materials 0.000 claims description 3
- 238000001556 precipitation Methods 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 238000000746 purification Methods 0.000 claims description 3
- 238000004088 simulation Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000006200 vaporizer Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract description 5
- 239000005715 Fructose Substances 0.000 abstract description 4
- 229930091371 Fructose Natural products 0.000 abstract description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 4
- 229930006000 Sucrose Natural products 0.000 abstract description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 229960004793 sucrose Drugs 0.000 abstract description 4
- 150000002016 disaccharides Chemical class 0.000 abstract description 3
- 238000005265 energy consumption Methods 0.000 abstract description 2
- 239000008103 glucose Substances 0.000 abstract description 2
- 238000011033 desalting Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000002386 leaching Methods 0.000 abstract 1
- 239000000835 fiber Substances 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000003463 adsorbent Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000004440 column chromatography Methods 0.000 description 2
- 239000008121 dextrose Substances 0.000 description 2
- 235000013681 dietary sucrose Nutrition 0.000 description 2
- 239000011552 falling film Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000005342 ion exchange Methods 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- 238000001728 nano-filtration Methods 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 230000035790 physiological processes and functions Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 244000298479 Cichorium intybus Species 0.000 description 1
- 235000007542 Cichorium intybus Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- ORXJMBXYSGGCHG-UHFFFAOYSA-N dimethyl 2-methoxypropanedioate Chemical compound COC(=O)C(OC)C(=O)OC ORXJMBXYSGGCHG-UHFFFAOYSA-N 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The invention relates to a method for producing high-purity inulin by using a chromatographic separation technology. The method comprises the concrete processes of (1) washing; (2) shredding; (3) leaching; (4) cleaning; (5) decoloring; (6) desalting; (7) chromatographic separation; (8) concentrating; and (9) drying. The inulin is separated and purified by using a three-component six-column SSMB (sequential simulated moving bed) chromatographic technology, so that the contents of effective components in the inulin can be up to more than 95%, and the recover rate of the inulin can be up to more than 95%. The contents of glucose, fructose and disaccharide (cane sugar) are greatly reduced, the functions of the high-purity inulin are increased, and meanwhile, the application range of the high-purity inulin is also widened. The method is good in separating effect, low in energy consumption and free of environment pollution.
Description
Technical field
The present invention relates to biomedicine field, especially a kind of production method of inulin.
Background technology
Inulin, also known as synanthrin, is water-soluble dietary fibre, and food fibre is one of human body seven major nutrient.Inulin is a kind of biological polyoses, is natural plant extracts, generally extracts from witloof or jerusalem artichoke.Molecular formula is (C6H10O5) n.Inulin to be connected with-(2,1) glycosidic link by multiple D-fructofuranose molecule and generates, each synanthrin molecule end with a-(1,2) glycosidic link connects a glucosyl residue, the polymerization degree is generally 2 ~ 60, and mean polymerisation degree is 10-30.Its chain length and molecular size range relevant with harvest season, crop maturity degree, plant origin, weather, soil and process of manufacture.Inulin not only has the physiological function of oligofructose, also has the physiological effect of food fibre.So inulin is bifidus factor and food fibre.In deep processing, domesticly to start late, current domestic main Nanofiltration Membrane Separation Technology produces inulin, the states such as its quality product and Europe, the U.S. differ greatly, purity is mostly below 80%, and the rate of recovery of inulin is also very low, the content requirement of high-purity inulin, more than 95%, uses nanofiltration separation technology to be difficult to reach this standard.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, provide a kind of chromatographic separation technology to produce the method for high-purity inulin, the high-purity inulin of production, there is the physiological function of functional Polylevulosan, also have the physiological effect of food fibre.
For achieving the above object, the technical scheme that the present invention takes is: a kind of chromatographic separation technology produces the method for high-purity inulin, and its concrete steps are as follows:
(1) clean: the silt washing away jerusalem artichoke surface with the clear water of 10-20 DEG C, removing impurity;
(2) chopping: utilize square position filament cutter to be cut into thread by cleaned jerusalem artichoke, jerusalem artichoke is cut into silk and is conducive to
In the shortest time, extracted as much as possible by inulin with less moisture from jerusalem artichoke cell, dish slice length is at more than 8m/100g, and fragment is less than 5%, not containing connection sheet;
(3) lixiviate: dish slice delivered in continuous diffuser, the hot water stop 80-120 adding 45-75 DEG C divides
Clock, obtains diffusion juice;
(4) peace and quiet: to adopt carbonatation process cleaning technique, in diffusion juice, add the CaCO of jerusalem artichoke weight 0.15-0.35%
3solution, regulates diffusion juice pH value to 11.2, reacts 15 minutes, then pass into carbonic acid gas, regulate pH to be 10.8, react 10 minutes to protein coacervation point, cohesion albumen; Remove impurity further by the precipitation of calcium carbonate, obtain just feed liquid;
(5) decolour: the craboraffin adding just feed liquid quality 3% in first feed liquid, stirs, be heated to 78-83 DEG C, reaction 30min, the pigment in absorption feed liquid;
(6) desalination: utilize macroporous type weak base anion resins to decolour the first feed liquid after decolouring, cloudy from
Sub-exchange resin decolouring realizes mainly through adsorption with to the exchange interaction of charged pigment molecule, then carry out desalination with gel-type strong-acid cation-exchange resin, Zeo-karb is used to the softening ion exchange process namely removing divalence and polyvalent cation;
(7) chromatographic separation: adopt continous way chromatography processes, enters SSMB order by the first feed liquid after desalination
Formula is simulation moving-bed, carries out the separation and purification of inulin and monose, obtains fine fodder liquid; By the mechanism of action of macroporous adsorbent resin in industrial chromatography system, inulin is separated with the component such as fructose, dextrose plus saccharose;
(8) concentrated: fine fodder liquid to be entered triple effect falling-film evaporator and carries out evaporation concentration, after concentrated, feed liquid brix is 35-40;
(9) dry: to utilize press spray drying tower by the fine fodder liquid after concentrated by high pressure homogenizer mist
Change, fully contact with the high temperature air of 140-200 DEG C in spray-drying tower, flash evapn falls excessive moisture, obtains finished product inulin.
Described sequential simulated moving bed employing SSMB tri-component six column chromatography separation technology, six chromatographic columns are had in three component six post patterns, 6 recycle pumps, because its chromatographic column overall length is longer, release travel is long, and separated component can be separated fully, and it is larger that this pattern is applicable to separating difficulty, or separation purity requires the separation of higher inulin feed liquid, and select potassium type gelling cations inulin chromatogram dedicated separation resin according to the characteristic of inulin.
The invention has the beneficial effects as follows: adopt SSMB tri-component six post sequential type simulated moving bed chromatography technology separation purifying inulin, with this understanding, inulin feed liquid is divided into monosaccharide and disaccharide and inulin three kinds of components, wherein the active principle content of inulin can reach more than 95%, and the inulin rate of recovery can reach more than 95%.Glucose, fructose and disaccharide (sucrose) content reduce greatly, while improve product functionality, have also been enlarged product application scope.Its good separating effect of this technique, energy consumption are low, and environmentally safe.
Accompanying drawing explanation
Fig. 1 is schema of the present invention.
Embodiment
Embodiment 1, a kind of chromatographic separation technology produces the method for high-purity inulin, and its concrete steps are as follows:
(1) clean: the silt washing away jerusalem artichoke surface with the clear water of 10-20 DEG C, removing impurity;
(2) chopping: utilize square position filament cutter to be cut into thread by cleaned jerusalem artichoke, jerusalem artichoke is cut into silk and is conducive to
In the shortest time, extracted as much as possible by inulin with less moisture from jerusalem artichoke cell, dish slice length is at more than 8m/100g, and fragment is less than 5%, not containing connection sheet;
(3) lixiviate: dish slice delivered in continuous diffuser, the hot water stop 80-120 adding 45-75 DEG C divides
Clock, obtains diffusion juice;
(4) peace and quiet: to adopt carbonatation process cleaning technique, in diffusion juice, add the CaCO of jerusalem artichoke weight 0.15-0.35%
3solution, regulates diffusion juice pH value to 11.2, reacts 15 minutes, then pass into carbonic acid gas, regulate pH to be 10.8, react 10 minutes to protein coacervation point, cohesion albumen; Remove impurity further by the precipitation of calcium carbonate, obtain just feed liquid;
(5) decolour: the craboraffin adding just feed liquid quality 3% in first feed liquid, stirs, be heated to 78-83 DEG C, reaction 30min, the pigment in absorption feed liquid;
(6) desalination: utilize macroporous type weak base anion resins to decolour the first feed liquid after decolouring, cloudy from
Sub-exchange resin decolouring realizes mainly through adsorption with to the exchange interaction of charged pigment molecule, then carry out desalination with gel-type strong-acid cation-exchange resin, Zeo-karb is used to the softening ion exchange process namely removing divalence and polyvalent cation;
(7) chromatographic separation: adopt continous way chromatography processes, enters SSMB order by the first feed liquid after desalination
Formula is simulation moving-bed, carries out the separation and purification of inulin and monose, obtains fine fodder liquid; By the mechanism of action of macroporous adsorbent resin in industrial chromatography system, inulin is separated with the component such as fructose, dextrose plus saccharose;
(8) concentrated: fine fodder liquid to be entered triple effect falling-film evaporator and carries out evaporation concentration, after concentrated, feed liquid brix is 35-40;
(9) dry: to utilize press spray drying tower by the fine fodder liquid after concentrated by high pressure homogenizer mist
Change, fully contact with the high temperature air of 140-200 DEG C in spray-drying tower, flash evapn falls excessive moisture, obtains finished product inulin.
Described sequential simulated moving bed employing SSMB tri-component six column chromatography separation technology, six chromatographic columns are had in three component six post patterns, 6 recycle pumps, because its chromatographic column overall length is longer, release travel is long, and separated component can be separated fully, and it is larger that this pattern is applicable to separating difficulty, or separation purity requires the separation of higher inulin feed liquid, and select potassium type gelling cations dedicated separation resin according to the characteristic of inulin.
Claims (2)
1. chromatographic separation technology produces a method for high-purity inulin, it is characterized in that concrete steps are as follows:
(1) clean: the silt washing away jerusalem artichoke surface with the clear water of 10-20 DEG C, removing impurity;
(2) chopping: utilize square position filament cutter to be cut into thread by cleaned jerusalem artichoke, dish slice length is at more than 8m/100g, and fragment is less than 5%, not containing connection sheet;
(3) lixiviate: dish slice is delivered in continuous diffuser, the hot water adding 45-75 DEG C stops 80-120 minute, obtains diffusion juice;
(4) peace and quiet: to adopt carbonatation process cleaning technique, in diffusion juice, add the CaCO of jerusalem artichoke weight 0.15-0.35%
3solution, regulates diffusion juice pH value to 11.2, reacts 15 minutes, then pass into carbonic acid gas, regulate pH to be 10.8, react 10 minutes to protein coacervation point, cohesion albumen; Remove impurity further by the precipitation of calcium carbonate, obtain just feed liquid;
(5) decolour: the craboraffin adding just feed liquid quality 3% in first feed liquid, stirs, be heated to 78-83 DEG C, reaction 30min, the pigment in absorption feed liquid;
(6) desalination: utilize macroporous type weak base anion resins to decolour the first feed liquid after decolouring, then carry out desalination with gel-type strong-acid cation-exchange resin;
(7) chromatographic separation: adopt continous way chromatography processes, by simulation moving-bed for the first feed liquid entering order formula after desalination, carry out the separation and purification of inulin and monose, obtain fine fodder liquid;
(8) concentrated: fine fodder liquid to be entered vaporizer and carries out evaporation concentration, after concentrated, feed liquid brix is 35-40;
(9) dry: be atomized by high pressure homogenizer by the fine fodder liquid after concentrating with press spray drying tower, fully contact with the high temperature air of 140-200 DEG C in spray-drying tower, flash evapn falls excessive moisture, obtains finished product inulin.
2. chromatographic separation technology produces the method for high-purity inulin as claimed in claim 1, it is characterized in that: described sequential simulated moving bed be three component six post patterns, have six chromatographic columns, 6 recycle pumps, resin is potassium type gelling cations inulin dedicated separation resin.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105950684A (en) * | 2016-07-01 | 2016-09-21 | 白银熙瑞生物工程有限公司 | Method for producing fructooligosaccharides by using jerusalem artichoke as raw material |
| CN106343543A (en) * | 2015-11-13 | 2017-01-25 | 翟丹云 | Inulin rose chewable tablets |
| CN106831893A (en) * | 2017-02-10 | 2017-06-13 | 广西轻工业科学技术研究院 | A kind of method that utilization molecular sieve Simulation moving bed prepares high-purity fructo oligosaccharides |
| CN107245116A (en) * | 2017-07-31 | 2017-10-13 | 寰龙特种糖业有限公司 | A kind of method that utilization SMBC technology prepares high-purity polyfructosan |
| CN107279236A (en) * | 2017-06-30 | 2017-10-24 | 武汉轻工大学 | A kind of low AGEs inulin cookies and preparation method thereof |
| CN110025983A (en) * | 2019-05-17 | 2019-07-19 | 山东兆光色谱分离技术有限公司 | A kind of chromatographic fractionation system and its separation method |
| CN111057166A (en) * | 2019-12-05 | 2020-04-24 | 晨光生物科技集团股份有限公司 | Method for preparing inulin |
| CN114540554A (en) * | 2020-11-26 | 2022-05-27 | 赛普特环保技术(厦门)有限公司 | Device and process for producing inulin by using inulin or jerusalem artichoke |
| CN115838390A (en) * | 2022-12-30 | 2023-03-24 | 保龄宝生物股份有限公司 | Method for preparing high-content 2' -fucosyllactose by utilizing three-component chromatographic separation technology |
-
2015
- 2015-05-22 CN CN201510265063.4A patent/CN104817652A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 刘宗利等: ""模拟移动床色谱分离技术在功能糖生产中的应用"", 《中国食品添加剂》 * |
| 李明: "《果蔬花卉深加工技术丛书 提取技术与实例》", 30 September 2006 * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106343543A (en) * | 2015-11-13 | 2017-01-25 | 翟丹云 | Inulin rose chewable tablets |
| CN105950684A (en) * | 2016-07-01 | 2016-09-21 | 白银熙瑞生物工程有限公司 | Method for producing fructooligosaccharides by using jerusalem artichoke as raw material |
| CN106831893A (en) * | 2017-02-10 | 2017-06-13 | 广西轻工业科学技术研究院 | A kind of method that utilization molecular sieve Simulation moving bed prepares high-purity fructo oligosaccharides |
| CN107279236A (en) * | 2017-06-30 | 2017-10-24 | 武汉轻工大学 | A kind of low AGEs inulin cookies and preparation method thereof |
| CN107245116A (en) * | 2017-07-31 | 2017-10-13 | 寰龙特种糖业有限公司 | A kind of method that utilization SMBC technology prepares high-purity polyfructosan |
| CN110025983A (en) * | 2019-05-17 | 2019-07-19 | 山东兆光色谱分离技术有限公司 | A kind of chromatographic fractionation system and its separation method |
| CN111057166A (en) * | 2019-12-05 | 2020-04-24 | 晨光生物科技集团股份有限公司 | Method for preparing inulin |
| CN111057166B (en) * | 2019-12-05 | 2021-10-08 | 晨光生物科技集团股份有限公司 | Method for preparing inulin |
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