CN104816884A - Aluminum foil packing bag provided with air inflation device inside - Google Patents
Aluminum foil packing bag provided with air inflation device inside Download PDFInfo
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- CN104816884A CN104816884A CN201510159547.0A CN201510159547A CN104816884A CN 104816884 A CN104816884 A CN 104816884A CN 201510159547 A CN201510159547 A CN 201510159547A CN 104816884 A CN104816884 A CN 104816884A
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Abstract
The invention relates to an aluminum foil packing bag provided with an air inflation device inside. The aluminum foil packing bag comprises an aluminum foil bag body and an upper seal, and further comprises the air inflation device arranged in the aluminum foil bag body, wherein a lower seal is arranged at the bottom of the aluminum foil bag body, and is connected with the air inflation device; the air inflation device comprises an outer wall, multiple projections, a sealing plug and a sealing plate; the outer wall is opened, and is connected with the lower seal; the middle of the bottom of the outer wall is opened, and is communicated with an inner cavity of the aluminum foil bag body; the multiple projections are fixed at the bottom of the outer wall; the sealing plug comprises a lower hard plastic piece and an upper circular soft rubber block connected as a whole; a groove I for clamping the multiple projections therein is formed in the bottom of the hard plastic piece; a groove II is formed in the connected place of the soft rubber block and the hard plastic piece; a gap is formed between the sealing plate and the sealing plug; the sealing plate is arranged between the lower seal and the sealing plug; a circular gap is formed in the middle of the sealing plate; the hard plastic piece is larger than the gap; the sealing plate is matched with the groove II in thickness; and the diameter of the circular gap is larger than the diameter of the inner wall ring of the groove II and smaller than the diameter of the soft rubber block.
Description
Technical field
The present invention relates to a kind of aluminum foil sack, particularly a kind of aluminum foil sack being subject to radiation effect or the easy oxidized article such as rotten for packed products pharmaceutical preparation, bulk drug and tealeaves etc. of built-in gas filled device.
Background technology
The packaging of medicine, bulk drug is selected with the stability of medicine, quality closely bound up.When selecting Key works Drug packing, the character according to medicine itself, formulation etc. are needed to select suitable Key works Drug packing, to ensure that medicine is in circulation and the stability in storing.It is improper that Key works Drug packing is selected, and makes medicine be subject to the impact of external factor, and after medicine degraded, drug content declines, and impurity content increases, and the occurrence probability of adverse drug reaction is increased, and even major concentration drops to below the mark, becomes substandard drug.
Photosensitive medicine, as phenol, adrenaline, vitamin A, D etc., needs material and the container of selecting effective shading.Easily oxidized medicine containing reduction groups such as phenolic group, enol base, aryl amines; and the medicine to humidity sensitive such as beta-lactam; need the packing selecting high-barrier; to reduce penetrating of moisture in air and oxygen; easily oxidized medicine, also can adopt the packaging increasing oxidizer or nitrogen protection.
A good packaging, can make medicine from the impact of external environment, in for a long time, keep drug effectiveness.The various aspects of performance such as photophobism, barrier of Aluminum Drum, In Aluminium Foil Packing is excellent, and quality is light, withstanding corrosion, anti-crushing, but Aluminum Drum packaging is expensive, In Aluminium Foil Packing pack with Aluminum Drum compared with more economical environmental protection.
In addition, except temperature, humidity, illumination, oxygen, impurity metal ion etc., the various electromagenetic wave radiations in environment can cause drug degradation equally, but the impact of electromagenetic wave radiation on medicine not yet draws attention.Radiant in external environment has broadcast television transmitter, mobile phone signal base station, electrified railway, power plant, voltage transformer and multiple common household electrical appliance as micro-wave oven, vision receiver etc., electromagnetic radiation is inevitably present in each place of drug delivery and storage, and it is remarkable to the degradation of some medicines, for the degraded preventing the electromagenetic wave radiation in surrounding environment from causing, the product that easily need be degraded to medicine etc. adopts actv. radiation resistant packaging.
Secondly, final drug preparation is packed, as cillin bottle packaging, in transportation, because temperature sharply changes, plug expand with heat and contract with cold cause fitting with cillin bottle not tight, outside air enters in cillin bottle, oxygen in air is by oxidation of drug, and cause the decline of medicine drug content, impurity increases, bad reaction increases, some also metachromatism can occur.If add anti-oxidation design in the external packing of this series products, this type of phenomenon can be avoided.
In addition, vacuumize yielding final drug preparation for some, as the medicinal tablet, injection etc. of carton package, be not suitable for adopting vacuum nitrogen filling sealing, what need to adopt other fills nitrogen sealing mode.
Therefore, develop and a kind of there is radiation proof, anti-oxidation effect and the packaging bag that can be used for vacuumizing the products such as yielding final drug preparation becomes particularly important.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, provides a kind of aluminum foil sack of built-in gas filled device.
The present invention is achieved by the following technical solutions:
The aluminum foil sack of this kind of built-in gas filled device, comprises aluminium foil bag body and upper sealing, also comprises and is located at the intrinsic gas filled device of aluminium foil bag, and described aluminium foil bag body bottom portion is provided with lower sealing, and described lower sealing connects gas filled device.
As optimization, described gas filled device comprises:
Outer wall, connects aluminium foil bag body, this outer wall upper shed and connect lower sealing, bottom middle opening and being connected with aluminium foil bag chamber body;
Several are protruding, are fixed on bottom described outer wall;
Sealing plug, it comprises and connecting for holistic bottom hard plastic sheet and upper circular soft rubber block, and the bottom of described hard plastic sheet has the groove I for snapping in several projections, and the junction of described soft rubber block and hard plastic sheet is provided with groove II;
Closing plate, and leave gap between sealing plug, to be located between lower sealing and sealing plug and to have circumferential notch in the middle of it;
The size of described hard plastic sheet is greater than breach, and the thickness of described closing plate and the thickness of groove II match, and the diameter of described circumferential notch is greater than the diameter of described groove II inwall ring and is less than the diameter of described soft rubber block.
As optimization, described outer wall comprises connected conical section and cylindrical part, described conical section upper shed and connect lower sealing, middle opening bottom described cylindrical part and being connected with aluminium foil bag chamber body, described projection is positioned at bottom the cylindrical part of described outer wall.
As optimization, described closing plate is located at the junction of conical section and cylindrical part.
As optimization, described hard plastic sheet is circular, and its diameter is 2-5 times of described soft rubber block diameter.
As optimization, described soft rubber block is positioned in the middle of the top of hard plastic sheet.
As optimization, described closing plate is plastic flagstone.
As optimization, described lower sealing place is provided with screw cap or rubber plug.
As optimization, the bottom of described aluminium foil bag body is circular or polygon.
As optimization, the material of described aluminium foil bag body is aluminium foil or clad aluminum foil.
The beneficial effect of the aluminum foil sack of a kind of built-in gas filled device of the present invention is:
The aluminum foil sack of this kind of built-in gas filled device, effectively can prevent the oxidation deterioration of content in transport and storage process, the inner packing that the phenomenon that particularly can prevent from expanding with heat and contract with cold when the temperature difference is larger in transportation causes impaired thus the medicine oxidation caused and contamination and deterioration, be particularly useful for the product such as yielding final drug reagent under negative pressure, effectively can prevent extraneous various radiation, maintain content stability, improve product quality.There is good actual application value and promotional value.
Accompanying drawing explanation
Be described further below in conjunction with the aluminum foil sack of accompanying drawing to this kind of built-in gas filled device:
Fig. 1 is the structural representation of the aluminum foil sack of this kind of built-in gas filled device;
Fig. 2 is the structural representation of the gas filled device of the aluminum foil sack of this kind of built-in gas filled device;
Fig. 3 is the vancomycin radiation contrast test result figure adopting British Pharmacopoeia liquid phase process gained.
In figure: 1 be aluminium foil bag body, 2 be upper sealing, 3 be lower sealing, 4 be gas filled device, 4.1 be outer wall, 4.2 for protruding, 4.3 be sealing plug, 4.3.1 is hard plastic sheet, 4.3.2 is groove I, 4.3.3 is soft rubber block, 4.3.4 be groove II, 4.4 is closing plate, 4.5 be breach.
Detailed description of the invention
For making object of the present invention, technical scheme and advantage clearly understand, to develop simultaneously embodiment referring to accompanying drawing, the present invention is described in more detail.
As Figure 1-Figure 2, the aluminum foil sack of this kind of built-in gas filled device, comprises bottom for the aluminium foil bag body 1 square, material is aluminium foil and upper sealing 2, also comprises the gas filled device 4 be located in aluminium foil bag body 1, be provided with lower sealing 3 bottom aluminium foil bag body 1, lower sealing 3 connects gas filled device 4.
Concrete, this gas filled device 4 comprises:
Connect the outer wall 4.1 of aluminium foil bag body 1, it comprises connected conical section and cylindrical part, conical section upper shed and connect lower sealing 3, middle opening bottom cylindrical part and with aluminium foil bag body 1 intracavity inter-connection;
3 projections 4.2, bottom the cylindrical part being fixed on outer wall 4.1;
Sealing plug 4.3, it comprises and connecting is holistic bottom hard plastic sheet 4.3.1 and upper circular soft rubber block 4.3.3, the bottom of hard plastic sheet 4.3.1 has the groove I 4.3.2 for snapping in several projections 4.2, design like this, the position of sealing plug 4.3 can be fixed, the junction of described soft rubber block 4.3.3 and hard plastic sheet 4.3.1 is provided with groove II 4.3.4,3 times that hard plastic sheet 4.3.1 is circle, its diameter is soft rubber block 4.3.3 diameter, soft rubber block 4.3.3 is positioned in the middle of the top of hard plastic sheet 4.3.1;
Closing plate 4.4, it is plastic flagstone, be located at and leave gap between the junction of conical section and cylindrical part and sealing plug 4.3 and have circumferential notch 4.5 in the middle of it;
The size of hard plastic sheet 4.3.1 is greater than breach 4.5, the described thickness of closing plate 4.4 and the thickness of groove II 4.3.4 match, and the diameter of described circumferential notch 4.5 is greater than the diameter of described groove II 4.3.4 inwall ring and is less than the diameter of described soft rubber block 4.3.3.
Design like this, during inflated with nitrogen, sealing plug 4.3 is pressed on protruding 4.2 by air pressure, and leave gap between sealing plug 4.3 and closing plate 4.4, nitrogen can be entered by the circumferential notch 4.5 on closing plate 4.4, and air flow line is shown in Fig. 2; Fill after nitrogen terminates, give this device mouth certain negative pressure by gas filled device, sealing plug 4.3 is picked up, the top seal of closing plate 4.4 is snapped in after circular soft rubber block 4.3.3 slight deformation, hard plastic sheet 4.3.1 stays closing plate 4.4 bottom, groove II 4.3.4 is concordant with closing plate 4.4, and now, the circumferential notch 4.5 on closing plate 4.4 seals by circular soft rubber block 4.3.3.
Concrete, lower sealing 3 place is provided with rubber plug, and so design, secondary strictly seals, better effects if.
Using method:
Load easily oxidized, easily degraded by electromagenetic wave radiation, vacuumize rear yielding content (the cillin bottle injection of such as carton package, ampoule injection stage etc.) front, square aluminum foil sack leaves sealing, after loading content, when top, two sides of minor face inwardly fold along center line, and two of long limit sides are fitted tightly on the top of aluminium foil bag, the bottom of aluminum foil sack is with the lower sealing of a built-in gas filled device, in bag, nitrogen is led to by gas filled device from this lower sealing during sealing, air in bag is discharged from the sealing of bag top, after in bag, air drains completely, vacuum nitrogen filling heat sealing machine or simple heat sealing machine is adopted to close upper sealing, stop inflated with nitrogen simultaneously, a negative pressure is executed to this lower sealing, the gas filled device mouth connecting lower sealing is salable closed, lower sealing strictly seals by further employing rubber plug.Square package Package gaps when storing is little, effectively can save storage space.
The charge of nitrogen should be the 10-80% of aluminum foil sack remaining space, and the volume after sealing is 0.01L-50L, both can available protecting content, can prevent breaking of aluminium foil bag self again.
This aluminum foil sack makes content be in nitrogen protection state; there is good shielding property; effectively can prevent the oxidation deterioration of content in transport and storage process; the inner packing that the phenomenon that particularly can prevent from expanding with heat and contract with cold when the temperature difference is larger in transportation causes impaired thus the medicine oxidation caused and contamination and deterioration, be particularly useful for the product such as yielding final drug reagent under negative pressure.
Concrete test:
The antibacterial efficacy of a drug of vancomycin is strong, can be used when other microbiotic are invalid to germ.Be mainly used in the caused system infections such as staphylococcus, clostridium difficile and enteric infection, as endocarditis, blood poisoning etc.Due in its structure containing some hydroxyl structures, unstable, easily oxidized and degraded by microwave.In addition, for investigating the radiation-proof effect of aluminum foil sack of the present invention, this test take vancomycin as trial drug.
Get certain pharmaceutical factory of China compared with the some white pigmented samples of new lot.Sample aliquot is become 3 parts, be placed in three same sealed vials.Wherein two protect with packaging of aluminium foil bag especially; the sample of a copy of it overcoat packaging of aluminium foil bag and portion are not placed in low frequency microwave radiation environment with the sample of packaging of aluminium foil bag simultaneously, and (radiation frequency is 10Hz; intensity is 10 μ T) 3 days, another overlaps the sample normal shelf of packaging of aluminium foil bag in contrast especially.After 3 days, three bottles of medicines are made into the identical liquid of concentration, are undertaken measuring and comparison by high performance liquid chromatography.
Result is as follows:
As can be seen from above-mentioned test and Fig. 3, by vancomycin, in middle intensity low frequency microwave radiation environment, (radiation frequency is 10Hz, and intensity is 10 μ T) places 3 days, and the drug content of vancomycin obviously declines.From result, the degradation of microwave to some medicines is remarkable, for the degraded preventing the electromagenetic wave radiation in surrounding environment from causing, the product that easily need be degraded to medicine etc. adopts actv. radiation resistant packaging, and the drug degradation that can effectively prevent electromagenetic wave radiation from causing after this packaging of aluminium foil bag of sample jacket.
In addition, the bottom of aluminium foil bag body also can be the polygon such as circle and triangle, packaging model uniqueness attractive in appearance, and can adapt to the needs of some special shape contents.
In addition, whether packaging of aluminium foil bag adds after in the end sealing that nitrogen protection determines by the character of content.For not easily oxidized but easily by the bulk drug that electromagenetic wave radiation is degraded, as hyaluronic acid, chondroitin sulfate etc., only can adopt vacuum-pumping and sealing.The molecular weight and molecular weight that this packaging of aluminium foil bag can effectively prevent the large molecule of hyaluronic acid from causing due to radiation, contributes to the quality improving product.In addition, vacuumize process and not only excessive gas is extracted, prevent contamination of products, can also packaging volume be reduced, reduce storage cost.
For easily oxidized bulk drug or easy oxidized rotten and frangible article, such as green tea, then adopt and fill nitrogen sealing.Nitrogen can effectively prevent green tea to be oxidized, and improves the mouthfeel of green tea and extends the shelf life, also playing actv. buffer action, prevents green tea broken.
For the final drug of cillin bottle, eye-drop liquid bottle, ampoule bottle, plastics or glass medicine bottle, aluminium foil plastic flagstone packaging, adopt and fill nitrogen sealing.In transportation, often run into destination and the larger situation of the departure place temperature difference, the effect of expanding with heat and contract with cold of the packing of product is obvious, easily produces poorly sealed phenomenon of even breaking.Such as, the plug of cillin bottle can because effect of expanding with heat and contract with cold causes cillin bottle poorly sealed, and the outer gas of cillin bottle enters in bottle, makes medicine oxidation deterioration in bottle.As increased this aluminium foil bag external packing in cillin bottle outside, and fill nitrogen sealing, when cillin bottle is poorly sealed, nitrogen can substitute air and enters in cillin bottle, effectively prevent medicine oxidation, and plays the effect of anti-medicine radiation degradation.The sample mailing to same user is unified, in loading aluminium foil bag of the present invention, also can ensure that residing for each independent formulations, environment is completely the same, strengthen Consumer's Experience.
Above-mentioned detailed description of the invention is only concrete case of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent implementations of equivalent variations.But every do not depart from the prerequisite of the technology of the present invention principle under, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, all should fall into scope of patent protection of the present invention.
Claims (10)
1. an aluminum foil sack for built-in gas filled device, comprises aluminium foil bag body and upper sealing, it is characterized in that: comprise and be located at the intrinsic gas filled device of aluminium foil bag, and described aluminium foil bag body bottom portion is provided with lower sealing, and described lower sealing connects gas filled device.
2. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 1, is characterized in that: described gas filled device comprises:
Outer wall, connects aluminium foil bag body, this outer wall upper shed and connect lower sealing, bottom middle opening and being connected with aluminium foil bag chamber body;
Several are protruding, are fixed on bottom described outer wall;
Sealing plug, it comprises and connecting for holistic bottom hard plastic sheet and upper circular soft rubber block, and the bottom of described hard plastic sheet has the groove I for snapping in several projections, and the junction of described soft rubber block and hard plastic sheet is provided with groove II;
Closing plate, and leave gap between sealing plug, to be located between lower sealing and sealing plug and to have circumferential notch in the middle of it;
The size of described hard plastic sheet is greater than breach, and the thickness of described closing plate and the thickness of groove II match, and the diameter of described circumferential notch is greater than the diameter of described groove II inwall ring and is less than the diameter of described soft rubber block.
3. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 2, it is characterized in that: described outer wall comprises connected conical section and cylindrical part, described conical section upper shed and connect lower sealing, middle opening bottom described cylindrical part and being connected with aluminium foil bag chamber body, described projection is positioned at bottom the cylindrical part of described outer wall.
4. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 3, is characterized in that: described closing plate is located at the junction of conical section and cylindrical part.
5. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 2, is characterized in that: described hard plastic sheet is for circular, and its diameter is 2-5 times of described soft rubber block diameter.
6. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 5, is characterized in that: described soft rubber block is positioned in the middle of the top of hard plastic sheet.
7. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 2, is characterized in that: described closing plate is plastic flagstone.
8. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 1, is characterized in that: described lower sealing place is provided with screw cap or rubber plug.
9. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 1, is characterized in that: the bottom of described aluminium foil bag body is circular or polygon.
10. the aluminum foil sack of a kind of built-in gas filled device as claimed in claim 1, is characterized in that: the material of described aluminium foil bag body is aluminium foil or clad aluminum foil.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510159547.0A CN104816884B (en) | 2015-04-07 | 2015-04-07 | Aluminum foil packing bag provided with air inflation device inside |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510159547.0A CN104816884B (en) | 2015-04-07 | 2015-04-07 | Aluminum foil packing bag provided with air inflation device inside |
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| CN104816884A true CN104816884A (en) | 2015-08-05 |
| CN104816884B CN104816884B (en) | 2017-04-26 |
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| WO2009031018A2 (en) * | 2007-09-05 | 2009-03-12 | Haemotronic Advanced Medical Technologies S.P.A. | Check valve for a medical device |
| CN101482104A (en) * | 2009-01-07 | 2009-07-15 | 陈仁多 | Multi-functional inflator |
| CN201816889U (en) * | 2010-09-20 | 2011-05-04 | 广东省农业科学院兽医研究所 | Extraction-free vacuum bag |
| CN202657409U (en) * | 2012-06-20 | 2013-01-09 | 刘同益 | Unidirectional mechanical exhaust valve special for free vacuum package |
| CN103097717A (en) * | 2010-09-13 | 2013-05-08 | 罗伯特·博世有限公司 | Valve, in particular of a hydraulic piston pump |
| CN204587691U (en) * | 2015-04-07 | 2015-08-26 | 北京泰克美高新技术有限公司 | A kind of aluminum foil sack of built-in gas filled device |
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2015
- 2015-04-07 CN CN201510159547.0A patent/CN104816884B/en active Active
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2037418U (en) * | 1988-08-26 | 1989-05-10 | 崔世成 | Multipurpose gas charging mouth for motorcycle |
| DE29903432U1 (en) * | 1999-02-25 | 1999-06-10 | Kress Karl Peter Dr | Packaging for perishable food |
| CN2706602Y (en) * | 2004-06-03 | 2005-06-29 | 巫新财 | Inflator for inflatable article |
| CN2859140Y (en) * | 2005-11-24 | 2007-01-17 | 南京沪江复合材料有限公司 | Compound plastic aluminum bag dedicated unidirectional air outlet valve |
| CN2872017Y (en) * | 2006-01-17 | 2007-02-21 | 伟泓丞实业股份有限公司 | Gas valve |
| CN2929392Y (en) * | 2006-07-07 | 2007-08-01 | 汪玉华 | Air valve of inflating product |
| CN201058688Y (en) * | 2007-07-09 | 2008-05-14 | 章澄 | Plastic-aluminum composite vacuum gas packing bag |
| WO2009031018A2 (en) * | 2007-09-05 | 2009-03-12 | Haemotronic Advanced Medical Technologies S.P.A. | Check valve for a medical device |
| CN101482104A (en) * | 2009-01-07 | 2009-07-15 | 陈仁多 | Multi-functional inflator |
| CN103097717A (en) * | 2010-09-13 | 2013-05-08 | 罗伯特·博世有限公司 | Valve, in particular of a hydraulic piston pump |
| CN201816889U (en) * | 2010-09-20 | 2011-05-04 | 广东省农业科学院兽医研究所 | Extraction-free vacuum bag |
| CN202657409U (en) * | 2012-06-20 | 2013-01-09 | 刘同益 | Unidirectional mechanical exhaust valve special for free vacuum package |
| CN204587691U (en) * | 2015-04-07 | 2015-08-26 | 北京泰克美高新技术有限公司 | A kind of aluminum foil sack of built-in gas filled device |
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| CN104816884B (en) | 2017-04-26 |
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Address after: Room 152, Building 1, 10 Xinghuo Road, Science City, Fengtai District, Beijing 100070 Co-patentee after: Huaxi Biotechnology Co., Ltd. Patentee after: Beijing Taikemei Hi-Tech Co., Ltd. Address before: Room 152, Building 1, 10 Xinghuo Road, Science City, Fengtai District, Beijing 100070 Co-patentee before: Bloomage Freda Biopharm Co., Ltd. Patentee before: Beijing Taikemei Hi-Tech Co., Ltd. |