CN104800249A - Ganoderma lucidum spore powder with artificially reconstructed spore wall and preparation method thereof - Google Patents
Ganoderma lucidum spore powder with artificially reconstructed spore wall and preparation method thereof Download PDFInfo
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Abstract
The invention discloses ganoderma lucidum spore powder with artificially reconstructed spore wall and a preparation method thereof. The product adopts artificial technology to construct a complete new sporoderm again for the ganoderma lucidum spore powder with broken wall, and the method comprises the following steps: selecting soluble natural plant polysaccharide or a composition of plant polysaccharide and plant protein as an outer wall material, adding an auxiliary agent to prepare a sol solution, dispersing and mixing wall-broken ganoderma spore powder in the sol solution, uniformly coating and packing each wall-broken ganoderma spore particle under the turbulence and cavitation action of a homogenizer, carrying out atomization granulation and drying setting procedures to quickly solidify the outer wall material to form a new artificial spore wall, drying, collecting a product, sieving, packaging and storing. The preparation technology of the ganoderma lucidum spore powder for artificially reconstructing spore wall is deepening and extending the processing technology of ganoderma lucidum spore wall breaking, effectively solves the problems of stability, taste masking, dispersibility and the like of the wall-broken ganoderma lucidum spore powder, and particularly has the characteristic of quick disintegration of artificial spore wall and the same bioavailability as the wall-broken spore powder.
Description
Technical field
The present invention relates to a kind of lucid ganoderma spore essence deep process technology field, specifically, relate to Ganoderma spore powder of a kind of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre and preparation method thereof.
Background technology
Ganoderma is described as since ancient times " Herba mesonae chinensis ", tool strengthening the body resistance effect.Ganoderma basidiospore be Ganoderma in the growth and maturity phase, the extremely small avette sexual cell ejected from lamella.Containing protein and amino acids, glycopeptide class, vitamins, carotene, sterols, triterpenes, alkaloids, fatty acid, lactone and inorganic ions etc. in Ganoderma basidiospore.Ganoderma basidiospore is the elite of Ganoderma, and its bioactive ingredients content is more than 70 times of Ganoderma sporophore.Ganoderma basidiospore has prevention and therapy tumor, blood pressure lowering blood glucose cholesterol, metabolism promoting, anti-cell senescence, suppresses the effects such as platelet aggregation, and its health-care effect and medical value obtain extensive accreditation.
Naturally the Ganoderma basidiospore collected is Powdered, is commonly called as Ganoderma spore powder, each spore size about 4.9 μm-9.5 μm.Ganoderma basidiospore has complicated spore ancient piece of jade, round, flat and with a hole in its centre structure, and connected by an inside and outside spore ancient piece of jade, round, flat and with a hole in its centre and pillar, its chemical component is based on chitin (52.08%-57.64%), and a large amount of depositions of Si, Ca, and spore ancient piece of jade, round, flat and with a hole in its centre rugged construction is hard.Clear up chitinous enzyme because human body lacks, chitin be not easily again gastric acid degradation, takes in a Ganoderma spore ancient piece of jade, round, flat and with a hole in its centre after human body not digested, and hard spore ancient piece of jade, round, flat and with a hole in its centre structural limitations spore inherent bioactive ingredients discharges and efficacy exertion, and in body, availability is low.
For overcoming spore ancient piece of jade, round, flat and with a hole in its centre obstacle, lot of documents reports the achievement in research of orcible entry Ganoderma spore sporoderm, multiple technologies method as wall enzymolysis, spore germination, cal rolling, ultrasonic, microwave, freezing etc. to be employed, wall breaking technology constantly improve the sporoderm-broken rate substantially increasing Ganoderma spore powder.At present, the Ganoderma spore powder of the high sporoderm-broken rate of a large amount of circulation on market, its sporoderm-broken rate reaches more than 95%, and even 99%, breaking trachytectum technology has played important function in lifting value utilitarian.
Although Ganoderma spore powder with cellular wall broken improves bioavailability, but, there is following problem in actual applications: the first, after breaking cellular wall, Ganoderma spore structure is subject to heavy damage, owing to lacking external protection, easily there is oxidation reaction in the contents such as terpenes, fatty acid, glycopeptide class, vitamins, causes spore powder to go bad, reduced shelf-life; The second, Ganoderma spore powder inherently slightly bitterness, breaking cellular wall artifact alkaloids etc. causes bitter taste to increase the weight of, taste bad; Three, after breaking cellular wall, the specific surface area of spore powder increases, and surface energy also significantly increases, and particle is in unsteady state, thus occurs agglomeration, and dispersibility is poor.Dispersibility is bad, the application of links such as being unfavorable for compatibility, packing, brew.This illustrates that wall breaking technology can't solve Problems existing in Ganoderma spore completely, and high Ganoderma spore powder with cellular wall broken obviously also exists deficiency to a certain degree.
The present invention is based on spore ultrastructure and the characteristic of Ganoderma spore, with the Ganoderma spore powder of breaking cellular wall for raw material, natural plant polyose, vegetable protein etc. is selected to be outer wall materials, with principles such as Biotechnology, structure biology, biochemistry, pharmaceutic adjuvant, galenic pharmacies for instructing, employing artificial technology is that the Ganoderma spore of breaking cellular wall rebuilds new outer wall, obtains the glossy ganoderma spore product with artificial outer wall.Owing to establishing new sporoderm external protection; solve the aspect existing problems such as the stability of sporoderm-broken Ganoderma spore, taste masking, dispersibility; simultaneously; because outer wall selection is that natural soluble is in the biomacromolecule of water; be easy to disintegrate, guarantee that the Ganoderma spore reconstructing a spore ancient piece of jade, round, flat and with a hole in its centre has same high bioavailability with exosporium-broken spore.
At present, there is not yet related documents or the report of artificial reconstruction Ganoderma sporoderm spore powder.
Summary of the invention
The object of this invention is to provide a kind of Ganoderma spore powder deep processed product and preparation method thereof; specifically to the Ganoderma spore of breaking cellular wall; artificial technology is taked to rebuild complete sporoderm; obtain the Ganoderma spore powder of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre; exactly, described artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre refers in particular to the outer artificial constructed film like protective layer of exosporium-broken spore.
The object of the present invention is achieved like this: with a remaining spore ancient piece of jade, round, flat and with a hole in its centre for sporoderm-broken Ganoderma spore for set accole, hang under collosol state and wrap up in transparent exterior material, by the even extension of homogenizing, atomization pelletize, dry setting program, outer wall materials is made to be solidified to form a new artificial spore ancient piece of jade, round, flat and with a hole in its centre, thus prepare Ganoderma spore powder processing new product, the i.e. Ganoderma spore powder of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre.
The present invention is achieved by the following technical solutions:
Natural for solubility outer wall materials is dissolved under the thermal condition of 50 DEG C-60 DEG C, add auxiliary agent and be mixed with the sol solutions that total concentration is 1%-5%, Ganoderma spore powder with cellular wall broken is added by glue quality 10%-20%, after dispersion mixing, the even extension of homogenizing 2 times-4 times under 20MPa-60MPa condition, pelletize, dry setting is atomized in spray dryer, nebulizer frequency 45Hz-55Hz, sample size 0.1mL/min-0.8mL/min, inlet temperature 180 DEG C-220 DEG C, leaving air temp 80 DEG C-120 DEG C, product is collected after drying, sieve, packaging, storage.
Described Ganoderma spore powder with cellular wall broken is sporoderm-broken rate more than 99%, by screening, obtains particle size range 5.0 μm of-9.0 μm of high-purity powders.
Described outer wall materials is mainly natural biological macromole, comprises the compositions of soluble polysaccharide or derivatives thereof, soluble protein or derivatives thereof or the polysaccharide mixed by a certain percentage and albumen.
Described soluble polysaccharide is the macromole of plant source, comprise starch, cellulose ether, pectin, arabic gum, sodium alginate, gellan gum, mannan, carrageenan, guar gum and there is film property other plant polysaccharide, or at least one of the derivant of above-mentioned polysaccharide or more than one.
Preferably, soluble polysaccharide is starch or hydroxypropyl emthylcellulose.
Described soluble protein is the macromole of plant source, comprises zein, wheat protein, soybean protein, cottonseed protein and has film property other plant Seed Storage Protein, or at least one of above-mentioned protein derivatives or more than one.
Preferably, solubility egg is soybean protein isolate.
Described encapsulated auxiliary agent refers to have the micromolecule strengthening film property or improve interface interaction, mainly comprise Span, Tween, sucrose fatty acid ester, glycerol, sorbitol, propylene glycol ester, gluconolactone, at least one of calcium gluconate or more than one.
Preferably, encapsulated auxiliary agent is Span or sucrose fatty acid ester, or combines by a certain percentage.
The even extension of described homogenizing adopts high pressure homogenizer.
Described atomization pelletize, dry setting adopt spray dryer.
Advantage of the present invention is:
The Ganoderma spore powder technology of preparing of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre of the present invention, the in-depth to breaking trachytectum of glossy ganoderma process technology and extension, the problems such as the stability of effective solution Ganoderma spore powder with cellular wall broken, taste masking, dispersibility, especially artificial sporoderm has fater disintegration characteristic, has identical bioavailability with spore powder with crushed sporoderm.At present, on market, Ganoderma spore product is a lot, and many products have tested recipe, processing technique and consumption market.Utilize reconstruct spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore of the present invention to make raw material, the composition and engineering of existing various product need not be adjusted, be easy to market and accept.The present invention is that Ganoderma spore utilization provides intensive processing technology, and equipment is simple, simple operation, and outer wall materials wide material sources are cheap.
Accompanying drawing explanation
Fig. 1 is the Ganoderma spore powder figure of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre of the present invention;
Fig. 2 is the Ganoderma spore scanning electron microscope (SEM) photograph of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre of the present invention.
Detailed description of the invention
Embodiment 1:
The formula (by mass percentage) of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore powder: Ganoderma spore powder with cellular wall broken 10%-20%, is advisable with 15%; Hydroxypropyl emthylcellulose 1%-3%, is advisable with 2%; Soybean protein isolate 1%-2%, is advisable with 1.5%; Span 0.01%-0.3%, is advisable with 0.2%; Sucrose fatty acid ester 0.01%-0.3%, is advisable with 0.1%; Surplus is pure water.
After first hydroxypropyl emthylcellulose and soybean protein isolate being dissolved respectively under 50 DEG C of-60 DEG C of stirring conditions, mixing, add Span and sucrose fatty acid ester, be mixed with the sol solutions that total concentration is 3% ~ 4%, Ganoderma spore powder with cellular wall broken is dispersed in glue, homogenizing 3 times-4 times under 30MPa-40MPa condition, open spray dryer, nebulizer frequency 45Hz-55Hz is set, sample size 0.2mL/min-0.3mL/min, inlet temperature 190 DEG C-210 DEG C, leaving air temp 90 DEG C-100 DEG C, collects product after drying, sieves, packaging, storage.
Embodiment 2:
The formula (by mass percentage) of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore powder: Ganoderma spore powder with cellular wall broken 10%-20%, is advisable with 15%; Carrageenan 1%-2%, is advisable with 1.5%; Zein 1%-2%, is advisable with 1.5%; Span 0.01%-0.3%, is advisable with 0.2%; Sorbitol 0.01%-0.3%, is advisable with 0.1%; Surplus is pure water.
After first carrageenan and zein being dissolved respectively under 50 DEG C of-60 DEG C of stirring conditions, mixing, add Span and sorbitol, be mixed with the sol solutions that total concentration is 3%-4%, Ganoderma spore powder with cellular wall broken is dispersed in glue, homogenizing 3 times-4 times under 30MPa-40MPa condition, open spray dryer, nebulizer frequency 45Hz-55Hz is set, sample size 0.2mL/min-0.3mL/min, inlet temperature 190 DEG C-210 DEG C, leaving air temp 90 DEG C-100 DEG C, collects product after drying, sieves, packaging, storage.
Embodiment 3:
The formula (by mass percentage) of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore powder: Ganoderma spore powder with cellular wall broken 10-20%, is advisable with 15%; Hydroxypropyl emthylcellulose 1-3%, is advisable with 2%; Potato starch 0.5-1.5%, is advisable with 1%; Soybean protein isolate 0.1-1%, is advisable with 0.5%; Tween 0.01%-0.3%, is advisable with 0.2%; Glycerol 0.01%-0.3%, is advisable with 0.1%; Surplus is pure water.
After first hydroxypropyl emthylcellulose, potato starch and soybean protein isolate being dissolved respectively under 50 DEG C of-60 DEG C of stirring conditions, mixing, add Tween and glycerol, be mixed with the sol solutions that total concentration is 3%-4%, Ganoderma spore powder with cellular wall broken is dispersed in glue, homogenizing even extension 3-4 time under 30MPa-40MPa condition, open spray dryer, nebulizer frequency 45Hz-55Hz is set, sample size 0.2mL/min-0.3mL/min, inlet temperature 190 DEG C-210 DEG C, leaving air temp 90 DEG C-100 DEG C, collects product after drying, sieves, packaging, storage.
Embodiment 4:
The formula (by mass percentage) of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore powder: Ganoderma spore powder with cellular wall broken 10-20%, is advisable with 15%; Sodium alginate 1-3%, is advisable with 2%; Tapioca 0.5%-1.5%, is advisable with 1%; Zein 0.1%-1%, is advisable with 0.5%; Tween0.01%-0.3%, is advisable with 0.2%; Calcium gluconate 0.01%-0.3%, is advisable with 0.1%; Surplus is pure water.
After first sodium alginate, tapioca and zein being dissolved respectively under 50 DEG C of-60 DEG C of stirring conditions, mixing, add Tween and calcium gluconate, be mixed with the sol solutions that total concentration is 3%-4%, Ganoderma spore powder with cellular wall broken is dispersed in glue, homogenizing 2 times-3 times under 30MPa-40MPa condition, open spray dryer, nebulizer frequency 45Hz-55Hz is set, sample size 0.2mL/min-0.3mL/min, inlet temperature 190 DEG C-210 DEG C, leaving air temp 90 DEG C-100 DEG C, collects product after drying, sieves, packaging, storage.
Embodiment 5:
The formula (by mass percentage) of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre Ganoderma spore powder: Ganoderma spore powder with cellular wall broken 10-20%, is advisable with 15%; Gellan gum 1-2%, is advisable with 1.5%; Hydroxypropyl emthylcellulose 1-2%, is advisable with 1.5%; Soybean protein isolate 0.1-1%, is advisable with 0.5%; Span 0.01%-0.3%, is advisable with 0.2%; Gluconolactone 0.01%-0.3%, is advisable with 0.1%; Surplus is pure water.
After first gellan gum, hydroxypropyl emthylcellulose and soybean protein isolate being dissolved respectively under 50 DEG C of-60 DEG C of stirring conditions, mixing, add Span and gluconolactone, be mixed with the sol solutions that total concentration is 3%-4%, Ganoderma spore powder with cellular wall broken is dispersed in glue, homogenizing 2 times-3 times under 30MPa-40MPa condition, open spray dryer, nebulizer frequency 45Hz-55Hz is set, sample size 0.2mL/min-0.3mL/min, inlet temperature 190 DEG C-210 DEG C, leaving air temp 90 DEG C-100 DEG C, collects product after drying, sieves, packaging, storage.
The Ganoderma spore powder of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre of the present invention has following characteristics:
Ganoderma spore powder (see Fig. 1) color of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre is dark brown, free from extraneous odour, without caking, good dispersion, even particle size, measure through laser particle size analyzer (Microtrac company of U.S. S-3500), its granularity is normal distribution, 5.3 μm-9.8 μm, particle size distribution region, is similar to the spore powder of natural collection.
Adopt scanning electron microscope (Hitachi S-4800) to scan artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre spore profile (see Fig. 2,7000 times), it is ellipsoidal particle shape thing that Fig. 2 shows artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre spore.The depressed area of the obvious visible larger area in this figure upper right corner is breaking cellular wall mouth once, through sporoderm reconstruct, forms complete Ganoderma spore.
The acidity of simulated gastric fluid, preparation pH is the HCl solution of 1.5, and get the Ganoderma spore powder sample of 5 artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centres, its wall film disintegrate situation is in table 1.The Ganoderma spore powder gastric juice disintegration time of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre is 2min-4min as shown in Table 1, and disintegration time is short, can discharge content fast in human body.
The Ganoderma spore powder outer wall disintegration time of a table 1 artificial reconstruction spore ancient piece of jade, round, flat and with a hole in its centre
。
Claims (9)
1. the Ganoderma spore powder of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre, it is characterized in that: based on ganoderma lucidium spore powder wall breaking technology, deep processing becomes to have the technical products of artificial new sporoderm, this product is powder, dark brown, even particle size, particle size distribution range 5.3 μm-9.8 μm, the Ganoderma spore powder collected with naturalness is similar to.
2. prepare the method for the Ganoderma spore powder of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre as claimed in claim 1 for one kind, it is characterized in that: first prepare outer wall materials sol solutions, by Ganoderma spore powder with cellular wall broken dispersion wherein, the even extension of homogenizing 2 times-4 times under 20MPa-60MPa condition, adopt spray dryer atomization pelletize, dry setting, nebulizer frequency 45Hz-55Hz, sample size 0.1mL/min-0.8mL/min, inlet temperature 180 DEG C-220 DEG C, leaving air temp 80 DEG C-120 DEG C, collects product after drying, sieves, packaging, storage.
3. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to claim 1,2 and preparation method thereof, is characterized in that: described Ganoderma spore powder with cellular wall broken is sporoderm-broken rate more than 99%, and Sieving and casing scope is high-purity powder of 5.0 μm-9.0 μm.
4. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to claim 1,2 and preparation method thereof, it is characterized in that: described outer wall materials is mainly natural biological macromole, comprise soluble polysaccharide or derivatives thereof, soluble protein or derivatives thereof or the polysaccharide allocated by a certain percentage and protein composition; Auxiliary agent preparation sol solutions is added during use.
5. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to claim 1,2,4 and preparation method thereof, it is characterized in that: described soluble polysaccharide is the natural macromolecular of plant source, comprise starch, cellulose ether, pectin, arabic gum, sodium alginate, gellan gum, mannan, carrageenan, guar gum and there is film property other plant polysaccharide, or at least one of above-mentioned polysaccharide derivates or more than one.
6. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to claim 1,2,4 and preparation method thereof, it is characterized in that: described soluble protein is the natural macromolecular of plant source, comprise soybean protein, zein, wheat protein, cottonseed protein and there is film property other plant Seed Storage Protein, or at least one of above-mentioned protein derivatives or more than one.
7. the Ganoderma spore powder and preparation method thereof of artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to claim 1,2,4, it is characterized in that: described auxiliary agent refers to have the micromolecule strengthening film property or improve interface interaction, mainly comprise Span, Tween, sucrose fatty acid ester, glycerol, sorbitol, propylene glycol ester, gluconolactone, at least one of calcium gluconate or more than one.
8. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to any one of claim 1-7 and preparation method thereof, it is characterized in that: described outer wall materials sol solutions is be dissolved in pure water by outer wall materials under the condition of 50 DEG C-60 DEG C, add 0.1%-1% auxiliary agent and be mixed with the solution that total concentration is 1%-5%.
9. Ganoderma spore powder of the artificial reconstruction's spore ancient piece of jade, round, flat and with a hole in its centre according to any one of claim 1-8 and preparation method thereof, is characterized in that: add in the 10%-20% ratio of outer wall materials sol solutions quality and disperse Ganoderma spore powder with cellular wall broken.
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| CN108065395A (en) * | 2017-12-21 | 2018-05-25 | 浙江健智元生物科技有限公司 | A kind of brain tonic and intelligence development body-building health food and preparation method thereof |
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