CN104799923A - Strutting bone grafting instrument for compression fracture of vertebral body - Google Patents
Strutting bone grafting instrument for compression fracture of vertebral body Download PDFInfo
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- CN104799923A CN104799923A CN201510216018.XA CN201510216018A CN104799923A CN 104799923 A CN104799923 A CN 104799923A CN 201510216018 A CN201510216018 A CN 201510216018A CN 104799923 A CN104799923 A CN 104799923A
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- bone grafting
- grafting instrument
- bone
- screw body
- strutting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7061—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant for stabilising vertebrae or discs by improving the condition of their tissues, e.g. using implanted medication or fluid exchange
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B2017/564—Methods for bone or joint treatment
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- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
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- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
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- General Health & Medical Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
The invention relates to a strutting bone grafting instrument for compression fracture of a vertebral body. The strutting bone grafting instrument is made from nanometer bionic bone; the strutting bone grafting instrument comprises a nail main body and external threads; the external threads cover the nail main body; the nail main body is of a hollow structure; a nail channel is arranged at the center of the nail main body; exudation holes are formed in the nail main body; the exudation holes are communicated with the outside; the exudation holes are distributed in the circumferential surface of the nail main body at 90-degree intervals. The strutting bone grafting instrument has the advantages that close cancellous bone can grow along the front edge on the surface, the 360-degree fusion of the cancellous bones around the nail channel is realized, the strength of the vertebral body is enhanced, the external fixing is not required, the wound of a patient is relieved, segment motion is remained, the cervical spondylosis is avoided and a huge economic cost is saved for the patient. The strutting bone grafting instrument is unique in design, the purpose of more effective fusing is achieved and the market application prospect is wide.
Description
Technical field
The present invention relates to technical field of medical instruments, specifically, be a kind of for cone compresses fracture strut bone grafting instrument.
Background technology
Osteoporosis reduces with bone amount, osseous tissue microstructure destruction or risk of bone fracture increase to the bone metabolism disturbance disease of feature, compression fracture of vertabral body is that perception is loosened modal complication, can cause deformity after vertebral body, chronic low back pain, then have and cause respiratory function to decline, dyspepsia, pain, loses self-care ability, spirit personality changes etc., make prevalence and mortality rate obviously increase.
Current treatment osteoporosis centrum compression fracture comprises following two types: one, the additional connecting rod of pedicle screw and horizontal connection, i.e. nail-stick system; Two, percutaneous puncture bone cement vertebroplasty or balloon kyphoplasty.
The additional connecting rod of existing pedicle screw and horizontal connection, i.e. nail-stick system, following problem is mainly there is: 1, osteoporosis causes sclerotin worsening condition, has a strong impact on the hold of screw: 2, screw loosening often occurs, exits when treating osteoporosis centrum compression fracture; 3, multi-segmental is fixing also can sacrifice segmentation movement, can cause cervical spondylosis; 4, huge financial burden is brought to patient.
Mainly there is following problem when treating osteoporosis centrum compression fracture in percutaneous puncture bone cement vertebroplasty or balloon kyphoplasty: 1, bone cement leakage loss hinders adjacent tissue, especially very careful when treating bursting fracture of vertebral body Cement; 2, when vertebral body posterior wall fractures is broken easily there is seepage in bone cement, enters canalis spinalis Spinal Cord, injected vertebral body front blood vessel and nerve when vertebral body antetheca breaks, and during soleplate fracture, bone cement infiltrates interbody space, the severe complication such as cause that adjacent vertebral bodies is subsided.
Chinese patent literature CN201410513728.4, on 09 29th, 2014 applying date, patent name is " compression fracture of vertabral body struts and puts bone device ", discloses a kind of compression fracture of vertabral body and struts and put bone device.It comprises the sleeve that can arrange inner core, a cylindrical shell is movably set with in described sleeve, the plunger that can move axially along this cylindrical shell is provided with at the inner chamber of cylindrical shell one end, this plunger promotes to be arranged on two in cylindrical shell and struts arm and stretch out this cylindrical shell other end, each external part strutting arm constrains in the inwall of the other end described in cylindrical shell, and described external part end face is fixed with and struts block.The present invention adopts cylindrical shell, plunger and struts arm and coordinates, and when plunger moves along cylindrical shell, struts arm by strutting block by pyramidal support, thus anterior longitudinal ligament, posterior longitudinal ligament and fibrous ring are not stretched, avoid injured nerve.But yet there are no report about a kind of bone grafting instrument that struts for the treatment of compression fracture of vertabral body of implantable artificial bone.
In sum, need a kind of raising cure rate and fractured vertebral body fusion badly, alleviate patient suffering and hospital stays, reduce operation risk, alleviate patient's expense, avoid sacrificing neighbouring section motion, prevent nearly sections from transporting the long term complications such as regression, that fractures for cone compresses struts bone grafting instrument.
Summary of the invention
The object of the invention is for deficiency of the prior art, there is provided a kind of and improve cure rate and fractured vertebral body fusion, alleviate patient suffering and hospital stays, reduce operation risk, alleviate patient's expense, avoid sacrificing neighbouring section motion, prevent nearly sections from transporting the long term complications such as regression, that fractures for cone compresses struts bone grafting instrument.
For achieving the above object, the technical scheme that the present invention takes is:
Strut a bone grafting instrument for compression fracture of vertabral body, the described bone grafting instrument that struts is formed by the anti-bone growth promoting manufacture of nanometer; The described bone grafting instrument that struts comprises screw body, external screw thread; Described external screw thread covers on screw body; Described screw body is hollow-core construction, and its center is provided with nail road; Described screw body is provided with bleeding holes; Described bleeding holes communicates with the external world; Described bleeding holes is spaced apart in 90 degree on screw body periphery.
Before described screw body apparent direction axially have 2 bleeding holes, and the centrage of bleeding holes is parallel to each other.
Described nail road is rounded.
Described nail road runs through screw body.
Described screw body is long is 45-50mm, and screw body diameter is 5.5-6.5mm.
Described screw body tip section is trapezoidal.
Described bleeding holes diameter is 2mm.
The invention has the advantages that:
1, of the present inventionly a kind ofly bone grafting instrument is strutted for compression fracture of vertabral body, evading existing internal fixtion and nail-stick system, to there is wound when treating osteoporosis centrum compression fracture large, screw hold is poor, screw easily loosens, exit, sacrifice segmentation movement, the problem such as cervical spondylosis, financial burden can be caused long term large.In conjunction with modern technologies achievement---nano bionic bone, can allow contiguous spongy bone in its surperficial forward position growth, realize the 360 degree of fusions of nail road surrounding spongy bone, strengthen vertebral body intensity, without the need to extenal fixation, alleviate patient trauma, reservation paragraph moves, and avoids cervical spondylosis, saves the economic cost that patient is huge;
2, percutaneous puncture bone cement vertebroplasty or balloon kyphoplasty easily form bone cement leakage loss when treating osteoporosis centrum compression fracture and hinder adjacent tissue, and cause the severe complications such as paralysis, pulmonary infarction, this research can avoid Cement;
3, this nail road strutting bone grafting instrument is roomy, good pressure environment is provided, utilize pressure that artificial bone solution seepage is entered vertebral fracture gap, promote that fracture gap is merged, the profile design of recycling screw uniqueness inserts powdered artificial's bone, fill up and compacting, realize surrounding by nail road bleeding holes and merge, a series of complication avoiding Cement to bring;
4, this struts bone grafting instrument design uniqueness, and evade prior art pluses and minuses, reach and better merge object, market application scenario is wide;
5, should operation is simple, safety is good, and wound is little, and post-operative recovery is fast, without the need to general anesthesia, appears strut bone grafting instrument at local anaesthesia down going channel.
Accompanying drawing explanation
Accompanying drawing 1 is a kind of front view strutted in bone grafting instrument for compression fracture of vertabral body of the present invention.
Accompanying drawing 2 is a kind of rearviews strutted in bone grafting instrument for cone compresses fracture of the present invention.
Accompanying drawing 3 is a kind of perspective view strutted in bone grafting instrument for cone compresses fracture of the present invention.
Accompanying drawing 4 is a kind of left and right view strutted in bone grafting instrument for compression fracture of vertabral body of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, detailed description of the invention provided by the invention is elaborated.
The Reference numeral related in accompanying drawing and ingredient as follows:
1. screw body 2. external screw thread
3. bleeding holes 4. is followed closely
Embodiment 1
Please refer to Fig. 1, Fig. 1 is a kind of front view strutted in bone grafting instrument for compression fracture of vertabral body of the present invention.Strut a bone grafting instrument for compression fracture of vertabral body, described in strut bone grafting instrument and comprise screw body 1, external screw thread 2; Described external screw thread 2 covers on screw body 1; Described screw body 1 is provided with bleeding holes 3.
Please refer to Fig. 2, Fig. 2 is a kind of rearview strutted in bone grafting instrument for cone compresses fracture of the present invention.Described bleeding holes 3 communicates with the external world; The tip section of described screw body 1 is trapezoidal.
Please refer to Fig. 3, Fig. 3 is a kind of perspective view strutted in bone grafting instrument for cone compresses fracture of the present invention.Described screw body 1 is long is 45-50mm, and screw body 1 diameter is 5.5-6.5mm; Described bleeding holes 3 diameter is 2mm; Described screw body 1 center is provided with nail road 4; Described bleeding holes 3 is spaced apart in 90 degree in screw body 1 radial direction; Before screw body 1 apparent direction axially have 2 bleeding holes 3, and the centrage of bleeding holes 3 is parallel to each other.
Please refer to Fig. 4, Fig. 4 is a kind of left and right view strutted in bone grafting instrument for compression fracture of vertabral body of the present invention.Described screw body 1 is hollow-core construction; Described nail road 4 is rounded; Described nail road 4 runs through screw body 1.
It should be noted that: described screw body 1 diameter is according to diverse location, and its screw body 1 diameter is different, and according to clinical experience, screw body 1 diameter is preferably 5.5-6.5mm; Described screw body 1 tip section is trapezoidal, contributes to screw body 1 and passes between vertebral body; Described bleeding holes 3 is spaced apart in 90 degree on screw body 1 periphery, makes surrounding spongy bone 360 degree fusion; Can artificial bone be filled in the thread groove of described external screw thread 2, make the artificial bone outside the artificial bone in screw body 1 and screw body 1 and screw body 1 connect into an entirety, enhance constant intensity and the degree of stability of screw body 1, reduce the generation of broken nail; The described bone grafting instrument that struts is formed by the anti-bone growth promoting manufacture of nanometer, and the anti-bone growth promoting of nanometer is a kind of new type bone material, and new bone also can realize well merging in its superficial growth, and has good intensity.Strutting bone grafting instrument contiguous spongy bone can be allowed to grow in its surperficial forward position by the manufacture of nano bionic bone, strengthens vertebral body intensity.Described struts bone grafting instrument in a state of use, strut after bone grafting instrument enters cone and extrude vertebral cancellous bone, indirect increase unit are bone density, artificial bone solution infiltrates vertebral fracture gap at certain pressure by the nail road 4 strutting bone grafting instrument, damages adjacent tissue, finally artificial bone is filled up passage and compacting when avoiding bone cement seeping at high temperature to leak outside, artificial bone merges with periphery spongy bone by the bleeding holes 3 of wall, interlayer inside and outside " H " type that formed, stablizes screw, increases vertebral body intensity.
Of the present inventionly a kind ofly strut bone grafting instrument for compression fracture of vertabral body, evading existing internal fixtion and nail-stick system, to there is wound when treating osteoporosis centrum compression fracture large, screw hold is poor, screw easily loosens, exit, sacrifice segmentation movement, the problem such as cervical spondylosis, financial burden can be caused long term large.In conjunction with modern technologies achievement---nano bionic bone, can allow contiguous spongy bone in its surperficial forward position growth, realize the 360 degree of fusions of nail road 4 surrounding spongy bone, strengthen vertebral body intensity, without the need to extenal fixation, alleviate patient trauma, reservation paragraph moves, and avoids cervical spondylosis, saves the economic cost that patient is huge; Percutaneous puncture bone cement vertebroplasty or balloon kyphoplasty easily form bone cement leakage loss when treating osteoporosis centrum compression fracture and hinder adjacent tissue, and cause the severe complications such as paralysis, pulmonary infarction, this research can avoid Cement; This nail road 4 strutting bone grafting instrument is roomy, good pressure environment is provided, utilize pressure that artificial bone solution seepage is entered vertebral fracture gap, promote that fracture gap is merged, the profile design of recycling screw uniqueness inserts powdered artificial's bone, fill up and compacting, realize surrounding by nail road 4 bleeding holes 3 and merge, a series of complication avoiding Cement to bring; It is unique that this struts bone grafting instrument design, and evade prior art pluses and minuses, reach and better merge object, market application scenario is wide; Operation is simple for this, and safety is good, and wound is little, and post-operative recovery is fast, without the need to general anesthesia, appears strut bone grafting instrument at local anaesthesia down going channel.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be considered as protection scope of the present invention.
Claims (7)
1. strut a bone grafting instrument for compression fracture of vertabral body, it is characterized in that, the described bone grafting instrument that struts is formed by the anti-bone growth promoting manufacture of nanometer; The described bone grafting instrument that struts comprises screw body, external screw thread; Described external screw thread covers on screw body; Described screw body is hollow-core construction, and its center is provided with nail road; Described screw body is provided with bleeding holes; Described bleeding holes communicates with the external world; Described bleeding holes is spaced apart in 90 degree on screw body periphery.
2. according to claim 1ly strut bone grafting instrument, it is characterized in that, before described screw body apparent direction axially have 2 bleeding holes, and the centrage of bleeding holes is parallel to each other.
3. according to claim 1ly strut bone grafting instrument, it is characterized in that, described nail road is rounded.
4. according to claim 1ly strut bone grafting instrument, it is characterized in that, described nail road runs through screw body.
5. according to claim 1ly strut bone grafting instrument, it is characterized in that, described screw body is long is 45-50mm, and screw body diameter is 5.5-6.5mm.
6. according to claim 1ly strut bone grafting instrument, it is characterized in that, described screw body tip section is trapezoidal.
7. according to claim 1ly strut bone grafting instrument, it is characterized in that, described bleeding holes diameter is 2mm.
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CN201510216018.XA CN104799923A (en) | 2015-04-30 | 2015-04-30 | Strutting bone grafting instrument for compression fracture of vertebral body |
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CN201510216018.XA CN104799923A (en) | 2015-04-30 | 2015-04-30 | Strutting bone grafting instrument for compression fracture of vertebral body |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106073952A (en) * | 2016-07-18 | 2016-11-09 | 中国人民解放军第二军医大学第二附属医院 | A kind of vertebral body booster treating compression fracture of vertabral body |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2636843Y (en) * | 2003-08-14 | 2004-09-01 | 四川国纳科技有限公司 | Artificial intervertebral fusion body |
US20040225292A1 (en) * | 2003-05-05 | 2004-11-11 | Sasso Ricardo C. | Bone anchor and methods of using the same |
US20040243130A1 (en) * | 2002-10-11 | 2004-12-02 | Spineco, Inc., An Ohio Corporation | Electro-stimulation and medical delivery device |
WO2006031397A1 (en) * | 2004-09-14 | 2006-03-23 | Spineco, Inc. | Implant device |
CN101426445A (en) * | 2006-04-21 | 2009-05-06 | 华沙整形外科股份有限公司 | Surgical fasteners with mechanical and osteogenic fixation means |
CN203677230U (en) * | 2013-12-02 | 2014-07-02 | 浙江康慈医疗科技有限公司 | Minimally invasive hollow multi-side hole spinal pedicle screw |
CN204683740U (en) * | 2015-04-30 | 2015-10-07 | 中国人民解放军第二军医大学 | A kind ofly strut bone grafting instrument for compression fracture of vertabral body |
-
2015
- 2015-04-30 CN CN201510216018.XA patent/CN104799923A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040243130A1 (en) * | 2002-10-11 | 2004-12-02 | Spineco, Inc., An Ohio Corporation | Electro-stimulation and medical delivery device |
US20040225292A1 (en) * | 2003-05-05 | 2004-11-11 | Sasso Ricardo C. | Bone anchor and methods of using the same |
CN2636843Y (en) * | 2003-08-14 | 2004-09-01 | 四川国纳科技有限公司 | Artificial intervertebral fusion body |
WO2006031397A1 (en) * | 2004-09-14 | 2006-03-23 | Spineco, Inc. | Implant device |
CN101426445A (en) * | 2006-04-21 | 2009-05-06 | 华沙整形外科股份有限公司 | Surgical fasteners with mechanical and osteogenic fixation means |
CN203677230U (en) * | 2013-12-02 | 2014-07-02 | 浙江康慈医疗科技有限公司 | Minimally invasive hollow multi-side hole spinal pedicle screw |
CN204683740U (en) * | 2015-04-30 | 2015-10-07 | 中国人民解放军第二军医大学 | A kind ofly strut bone grafting instrument for compression fracture of vertabral body |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106073952A (en) * | 2016-07-18 | 2016-11-09 | 中国人民解放军第二军医大学第二附属医院 | A kind of vertebral body booster treating compression fracture of vertabral body |
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Application publication date: 20150729 |